MTMR4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)4.95288306
2layer formation in cerebral cortex (GO:0021819)4.89374010
3establishment of mitochondrion localization (GO:0051654)4.60252420
4establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.52250077
5mitochondrion transport along microtubule (GO:0047497)4.52250077
6nucleobase catabolic process (GO:0046113)4.44947720
7axonal fasciculation (GO:0007413)4.42516439
8synaptic vesicle maturation (GO:0016188)4.19197751
9neuron recognition (GO:0008038)4.03486239
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.02792499
11response to pheromone (GO:0019236)4.02124049
12regulation of NFAT protein import into nucleus (GO:0051532)3.94546499
13regulation of short-term neuronal synaptic plasticity (GO:0048172)3.88294964
14sodium ion export (GO:0071436)3.86081257
15spliceosomal tri-snRNP complex assembly (GO:0000244)3.81426029
16cell migration in hindbrain (GO:0021535)3.79252303
17positive regulation of dendritic spine morphogenesis (GO:0061003)3.75843252
18locomotory exploration behavior (GO:0035641)3.52390663
19establishment of nucleus localization (GO:0040023)3.51103416
20neurotransmitter-gated ion channel clustering (GO:0072578)3.44815483
21histone H3-K4 trimethylation (GO:0080182)3.34990653
22neuronal ion channel clustering (GO:0045161)3.32968300
23pre-miRNA processing (GO:0031054)3.32669286
24glutamate secretion (GO:0014047)3.32354102
25dendritic spine morphogenesis (GO:0060997)3.30568313
26phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.29161291
27central nervous system neuron axonogenesis (GO:0021955)3.16385344
28synaptic vesicle exocytosis (GO:0016079)3.16376161
29neurotransmitter secretion (GO:0007269)3.16202494
30vocalization behavior (GO:0071625)3.14594506
31macroautophagy (GO:0016236)3.14483814
32dicarboxylic acid biosynthetic process (GO:0043650)3.14079344
33cerebral cortex radially oriented cell migration (GO:0021799)3.13898924
34substrate-independent telencephalic tangential migration (GO:0021826)3.13163043
35substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.13163043
36dendrite morphogenesis (GO:0048813)3.12496403
37nuclear pore complex assembly (GO:0051292)3.11899591
38regulation of nucleobase-containing compound transport (GO:0032239)3.07679870
39regulation of RNA export from nucleus (GO:0046831)3.06397413
40positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.06213114
41urea metabolic process (GO:0019627)3.06111125
42urea cycle (GO:0000050)3.06111125
43cerebellar Purkinje cell differentiation (GO:0021702)3.05313046
44regulation of neuronal synaptic plasticity (GO:0048168)3.01804778
45cytoskeletal anchoring at plasma membrane (GO:0007016)3.01727817
46regulation of synaptic vesicle exocytosis (GO:2000300)3.01162100
47synaptic vesicle docking involved in exocytosis (GO:0016081)3.01130061
48glucocorticoid receptor signaling pathway (GO:0042921)2.96645806
49regulation of synapse maturation (GO:0090128)2.95889178
50positive regulation of synapse maturation (GO:0090129)2.94135966
51semaphorin-plexin signaling pathway (GO:0071526)2.93901086
52L-phenylalanine catabolic process (GO:0006559)2.91363492
53erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.91363492
54regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.88531556
55activation of protein kinase A activity (GO:0034199)2.87222312
56histone H3-K36 demethylation (GO:0070544)2.87035798
57gamma-aminobutyric acid transport (GO:0015812)2.85369502
58RNA localization (GO:0006403)2.85285240
59peptidyl-lysine dimethylation (GO:0018027)2.84916079
60regulation of glutamate receptor signaling pathway (GO:1900449)2.83676098
61positive regulation of dendrite morphogenesis (GO:0050775)2.83672337
62negative regulation of dendrite morphogenesis (GO:0050774)2.83474188
63alpha-linolenic acid metabolic process (GO:0036109)2.82259019
64G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.81575387
65regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.78996004
66peptidyl-threonine phosphorylation (GO:0018107)2.78341635
67regulation of ARF protein signal transduction (GO:0032012)2.76740216
68exploration behavior (GO:0035640)2.73978807
69cerebellar granule cell differentiation (GO:0021707)2.72012408
70nuclear pore organization (GO:0006999)2.72001206
71mitochondrion localization (GO:0051646)2.71695390
72erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.68775241
73L-phenylalanine metabolic process (GO:0006558)2.68775241
74insulin-like growth factor receptor signaling pathway (GO:0048009)2.68741535
75protein localization to synapse (GO:0035418)2.68694236
76embryonic retina morphogenesis in camera-type eye (GO:0060059)2.68312538
77negative regulation of microtubule polymerization (GO:0031115)2.68283904
78pore complex assembly (GO:0046931)2.67664578
79histone H3-K9 demethylation (GO:0033169)2.67119428
80glutamate metabolic process (GO:0006536)2.66214357
81nitrogen cycle metabolic process (GO:0071941)2.65484291
82cerebellar Purkinje cell layer development (GO:0021680)2.65312455
83cell communication by electrical coupling (GO:0010644)2.64564915
84sympathetic nervous system development (GO:0048485)2.61604894
85presynaptic membrane organization (GO:0097090)2.61252815
86regulation of dendritic spine morphogenesis (GO:0061001)2.61021910
87triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.60532761
88lysine metabolic process (GO:0006553)2.60439906
89lysine catabolic process (GO:0006554)2.60439906
90neuromuscular process controlling balance (GO:0050885)2.60206780
91negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.59690036
92high-density lipoprotein particle remodeling (GO:0034375)2.59579076
93kynurenine metabolic process (GO:0070189)2.59129391
94presynaptic membrane assembly (GO:0097105)2.58748103
95mitotic sister chromatid cohesion (GO:0007064)2.58166941
96postsynaptic membrane organization (GO:0001941)2.56123545
97histone lysine demethylation (GO:0070076)2.55586379
98peptidyl-threonine modification (GO:0018210)2.55102530
99epoxygenase P450 pathway (GO:0019373)2.55018900
100intracellular estrogen receptor signaling pathway (GO:0030520)2.54761479
101negative regulation of neurotransmitter secretion (GO:0046929)2.54727489
102regulation of synapse structural plasticity (GO:0051823)2.53005408
103cellular ketone body metabolic process (GO:0046950)2.52478333
104nucleosome disassembly (GO:0006337)2.52203473
105protein-DNA complex disassembly (GO:0032986)2.52203473
106synaptic vesicle endocytosis (GO:0048488)2.51202100
107regulation of histone H3-K27 methylation (GO:0061085)2.51151878
108limb bud formation (GO:0060174)2.51054212
109dosage compensation (GO:0007549)2.50487315
110cellular response to nerve growth factor stimulus (GO:1990090)2.50484053
111response to nerve growth factor (GO:1990089)2.50484053
112midgut development (GO:0007494)2.50230301
113aromatic amino acid family catabolic process (GO:0009074)2.50064158
114regulation of synaptic vesicle transport (GO:1902803)2.49263995
115organelle transport along microtubule (GO:0072384)2.48944606
116negative regulation of sterol transport (GO:0032372)2.48837580
117negative regulation of cholesterol transport (GO:0032375)2.48837580
118negative regulation of fibrinolysis (GO:0051918)2.48799458
119regulation of dendrite morphogenesis (GO:0048814)2.48791498
120peptidyl-lysine trimethylation (GO:0018023)2.48143601
121proline transport (GO:0015824)2.47037325
122mating behavior (GO:0007617)2.46682236
123clathrin coat assembly (GO:0048268)2.45174467
124drug catabolic process (GO:0042737)2.45100599
125intestinal cholesterol absorption (GO:0030299)2.45049608
126regulation of long-term neuronal synaptic plasticity (GO:0048169)2.44105003
127corticosteroid receptor signaling pathway (GO:0031958)2.44075133
128histone demethylation (GO:0016577)2.43918909
129histone H3-K9 methylation (GO:0051567)2.43509012
130neuron cell-cell adhesion (GO:0007158)2.42709582
131phosphatidylinositol phosphorylation (GO:0046854)2.42600887
132central nervous system projection neuron axonogenesis (GO:0021952)2.41598017
133negative regulation of dendrite development (GO:2000171)2.41011761
134cell differentiation in hindbrain (GO:0021533)2.40048522
135vesicle transport along microtubule (GO:0047496)2.39424914
136peptidyl-lysine methylation (GO:0018022)2.39254437
137cellular response to prostaglandin stimulus (GO:0071379)2.39197893
138axon extension (GO:0048675)2.38992502
139stress granule assembly (GO:0034063)2.38720457
140cerebral cortex neuron differentiation (GO:0021895)2.38317259
141growth hormone receptor signaling pathway (GO:0060396)2.38092821
142amino acid import (GO:0043090)2.37658272
143cellular potassium ion homeostasis (GO:0030007)2.35586582
144negative regulation of catenin import into nucleus (GO:0035414)2.35463108
145intestinal absorption (GO:0050892)2.34872887
146regulation of clathrin-mediated endocytosis (GO:2000369)2.33030877
147positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.32122495
148auditory behavior (GO:0031223)2.31587441
149nerve growth factor signaling pathway (GO:0038180)2.31275373
150prepulse inhibition (GO:0060134)2.29922208
151regulation of cholesterol homeostasis (GO:2000188)2.29532239
152cytoplasmic mRNA processing body assembly (GO:0033962)2.28218703
153reverse cholesterol transport (GO:0043691)2.27266030
154cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.26107047
155cholesterol efflux (GO:0033344)2.26080422
156neurotransmitter transport (GO:0006836)2.25583681
157regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.24449827
158cell junction maintenance (GO:0034331)2.23720383
159ionotropic glutamate receptor signaling pathway (GO:0035235)2.22458864
160ketone body metabolic process (GO:1902224)2.21200694

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse4.99260728
2EZH2_22144423_ChIP-Seq_EOC_Human3.50543685
3* MYC_22102868_ChIP-Seq_BL_Human3.23481448
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.59692404
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.49929522
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.31542250
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.30513857
8E2F7_22180533_ChIP-Seq_HELA_Human2.23290433
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.21461138
10DROSHA_22980978_ChIP-Seq_HELA_Human2.10788915
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.04497891
12* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat2.00780940
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.00183799
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.00183799
15FOXM1_23109430_ChIP-Seq_U2OS_Human1.99965491
16* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.98368664
17SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.97924869
18* RARB_27405468_Chip-Seq_BRAIN_Mouse1.94331962
19REST_21632747_ChIP-Seq_MESCs_Mouse1.91647906
20* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.91121760
21JARID2_20064375_ChIP-Seq_MESCs_Mouse1.88342353
22TCF7_22412390_ChIP-Seq_EML_Mouse1.88205196
23SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.87399642
24* RXR_22158963_ChIP-Seq_LIVER_Mouse1.82995252
25KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.79543680
26RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.79293464
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.79144487
28RNF2_27304074_Chip-Seq_ESCs_Mouse1.79098627
29JARID2_20075857_ChIP-Seq_MESCs_Mouse1.77703589
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.77336096
31KDM2B_26808549_Chip-Seq_K562_Human1.74876277
32LXR_22158963_ChIP-Seq_LIVER_Mouse1.74835494
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.74521617
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.74516188
35SUZ12_27294783_Chip-Seq_ESCs_Mouse1.70344422
36* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.70259235
37ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.69619693
38WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.68967135
39SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.68023916
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.67688411
41SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.65739054
42CTNNB1_20460455_ChIP-Seq_HCT116_Human1.65206025
43REST_18959480_ChIP-ChIP_MESCs_Mouse1.64732139
44SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.64529880
45ZFP281_27345836_Chip-Seq_ESCs_Mouse1.59605777
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.56934410
47TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.55361296
48* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.53654167
49STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.51636035
50NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.50890099
51EED_16625203_ChIP-ChIP_MESCs_Mouse1.50711929
52BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.49881994
53CIITA_25753668_ChIP-Seq_RAJI_Human1.46865002
54NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.42637320
55EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.41004219
56TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.39947980
57DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.38297876
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.34612047
59DNAJC2_21179169_ChIP-ChIP_NT2_Human1.34231030
60SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.34200278
61GATA1_22025678_ChIP-Seq_K562_Human1.33086577
62GBX2_23144817_ChIP-Seq_PC3_Human1.33036326
63SALL1_21062744_ChIP-ChIP_HESCs_Human1.32682028
64WT1_25993318_ChIP-Seq_PODOCYTE_Human1.30287294
65AR_21572438_ChIP-Seq_LNCaP_Human1.29143265
66RING1B_27294783_Chip-Seq_ESCs_Mouse1.28978072
67TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.27902830
68* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.26456061
69ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26139350
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.25959492
71KDM2B_26808549_Chip-Seq_SUP-B15_Human1.25767913
72* AR_19668381_ChIP-Seq_PC3_Human1.24169628
73FOXA2_19822575_ChIP-Seq_HepG2_Human1.24110610
74CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.22885375
75YAP1_20516196_ChIP-Seq_MESCs_Mouse1.21355195
76KDM2B_26808549_Chip-Seq_DND41_Human1.19384456
77AHR_22903824_ChIP-Seq_MCF-7_Human1.19216535
78FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.18632879
79ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.16611801
80ARNT_22903824_ChIP-Seq_MCF-7_Human1.16164582
81SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14979806
82SOX2_21211035_ChIP-Seq_LN229_Gbm1.14719305
83NR3C1_23031785_ChIP-Seq_PC12_Mouse1.13824460
84CLOCK_20551151_ChIP-Seq_293T_Human1.13568049
85ZNF274_21170338_ChIP-Seq_K562_Hela1.10222999
86IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08352257
87ZNF263_19887448_ChIP-Seq_K562_Human1.07915375
88ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.07745462
89ELK4_26923725_Chip-Seq_MESODERM_Mouse1.07360106
90P300_27058665_Chip-Seq_ZR-75-30cells_Human1.06754340
91TP63_19390658_ChIP-ChIP_HaCaT_Human1.06598140
92RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.05635105
93* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05574085
94CTBP2_25329375_ChIP-Seq_LNCAP_Human1.05100258
95ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04556425
96GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04333446
97SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.04092161
98VDR_21846776_ChIP-Seq_THP-1_Human1.03900600
99SMAD4_21741376_ChIP-Seq_HESCs_Human1.03039497
100OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02303893
101ISL1_27105846_Chip-Seq_CPCs_Mouse1.02264312
102KDM2B_26808549_Chip-Seq_JURKAT_Human1.01506373
103CREB1_26743006_Chip-Seq_LNCaP_Human1.01398316
104RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.00871247
105TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97961819
106THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.97240377
107RXR_22108803_ChIP-Seq_LS180_Human0.97167221
108VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.95611696
109PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.95207513
110TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.94715550
111SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94320170
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94312269
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94312269
114SMAD4_21799915_ChIP-Seq_A2780_Human0.94284997
115* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93739068
116ESR2_21235772_ChIP-Seq_MCF-7_Human0.93517478
117FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.93035271
118KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.92848109
119TCF4_18268006_ChIP-ChIP_LS174T_Human0.92508974
120PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.91856280
121CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.91537760
122BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91232198
123TAF15_26573619_Chip-Seq_HEK293_Human0.90703479
124PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.90693884
125GATA1_19941827_ChIP-Seq_MEL_Mouse0.90406169
126IRF1_19129219_ChIP-ChIP_H3396_Human0.89337066
127* LXR_22292898_ChIP-Seq_THP-1_Human0.88900646
128* RUNX1_27514584_Chip-Seq_MCF-7_Human0.88544777
129POU5F1_16518401_ChIP-PET_MESCs_Mouse0.87669925
130IGF1R_20145208_ChIP-Seq_DFB_Human0.87652529
131E2F1_21310950_ChIP-Seq_MCF-7_Human0.86883169
132ESR1_15608294_ChIP-ChIP_MCF-7_Human0.86498648
133P53_22127205_ChIP-Seq_FIBROBLAST_Human0.85979353
134AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85384234
135POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.85086399
136CDX2_19796622_ChIP-Seq_MESCs_Mouse0.84526941
137CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84173678
138* SOX9_26525672_Chip-Seq_HEART_Mouse0.83524391

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.92385280
2MP0005360_urolithiasis4.15392786
3MP0005423_abnormal_somatic_nervous3.64520823
4MP0002139_abnormal_hepatobiliary_system3.62386641
5MP0008057_abnormal_DNA_replication2.99422972
6MP0002009_preneoplasia2.93574962
7MP0004270_analgesia2.82904517
8MP0003635_abnormal_synaptic_transmissio2.71957728
9MP0000778_abnormal_nervous_system2.70524647
10MP0003122_maternal_imprinting2.54985175
11MP0005085_abnormal_gallbladder_physiolo2.51958260
12MP0003880_abnormal_central_pattern2.47595426
13MP0002063_abnormal_learning/memory/cond2.32894290
14MP0003252_abnormal_bile_duct2.32127210
15MP0010234_abnormal_vibrissa_follicle2.29753014
16MP0000569_abnormal_digit_pigmentation2.23082918
17MP0005365_abnormal_bile_salt2.22065399
18MP0001348_abnormal_lacrimal_gland2.12601739
19MP0001346_abnormal_lacrimal_gland2.05042965
20MP0003329_amyloid_beta_deposits1.96120302
21MP0003705_abnormal_hypodermis_morpholog1.92339168
22MP0002064_seizures1.88139612
23MP0002138_abnormal_hepatobiliary_system1.87841876
24MP0009046_muscle_twitch1.82600628
25MP0005187_abnormal_penis_morphology1.80864628
26MP0009745_abnormal_behavioral_response1.80716884
27MP0004811_abnormal_neuron_physiology1.79656338
28MP0008961_abnormal_basal_metabolism1.78265504
29MP0000537_abnormal_urethra_morphology1.71757215
30MP0001666_abnormal_nutrient_absorption1.67018055
31MP0002653_abnormal_ependyma_morphology1.64162910
32MP0002184_abnormal_innervation1.62804723
33MP0000955_abnormal_spinal_cord1.62455423
34MP0009780_abnormal_chondrocyte_physiolo1.60607348
35MP0010329_abnormal_lipoprotein_level1.58061242
36MP0003123_paternal_imprinting1.57627711
37MP0003183_abnormal_peptide_metabolism1.57601021
38MP0008875_abnormal_xenobiotic_pharmacok1.53383770
39MP0002733_abnormal_thermal_nociception1.53058902
40MP0001486_abnormal_startle_reflex1.52611584
41MP0004858_abnormal_nervous_system1.51265382
42MP0002734_abnormal_mechanical_nocicepti1.50964911
43MP0002572_abnormal_emotion/affect_behav1.48592448
44MP0004885_abnormal_endolymph1.44662722
45MP0002909_abnormal_adrenal_gland1.42151999
46MP0003121_genomic_imprinting1.41036583
47MP0000604_amyloidosis1.36816570
48MP0005248_abnormal_Harderian_gland1.34389745
49MP0000566_synostosis1.33227556
50MP0005623_abnormal_meninges_morphology1.32499326
51MP0002166_altered_tumor_susceptibility1.31738616
52MP0006276_abnormal_autonomic_nervous1.28749196
53MP0001968_abnormal_touch/_nociception1.26191260
54MP0004742_abnormal_vestibular_system1.23272288
55MP0001440_abnormal_grooming_behavior1.22821821
56MP0002254_reproductive_system_inflammat1.20520766
57MP0002751_abnormal_autonomic_nervous1.18086568
58MP0003283_abnormal_digestive_organ1.17591334
59MP0002882_abnormal_neuron_morphology1.15406746
60MP0002152_abnormal_brain_morphology1.15379353
61MP0005409_darkened_coat_color1.13961592
62MP0003221_abnormal_cardiomyocyte_apopto1.13256991
63MP0005083_abnormal_biliary_tract1.13102853
64MP0002272_abnormal_nervous_system1.11268500
65MP0003787_abnormal_imprinting1.10140461
66MP0002822_catalepsy1.09374414
67MP0005386_behavior/neurological_phenoty1.08137163
68MP0004924_abnormal_behavior1.08137163
69MP0003632_abnormal_nervous_system1.08042874
70MP0009115_abnormal_fat_cell1.07748253
71MP0010030_abnormal_orbit_morphology1.07215676
72MP0002735_abnormal_chemical_nociception1.05678930
73MP0002557_abnormal_social/conspecific_i1.05245604
74MP0002066_abnormal_motor_capabilities/c1.03384556
75MP0001970_abnormal_pain_threshold1.01150008
76MP0005076_abnormal_cell_differentiation1.00312583
77MP0004264_abnormal_extraembryonic_tissu0.99401820
78MP0008569_lethality_at_weaning0.98596822
79MP0004185_abnormal_adipocyte_glucose0.98535870
80MP0003861_abnormal_nervous_system0.98030678
81MP0002736_abnormal_nociception_after0.97475381
82MP0003690_abnormal_glial_cell0.96717846
83MP0005645_abnormal_hypothalamus_physiol0.95878199
84MP0003634_abnormal_glial_cell0.92606515
85MP0003091_abnormal_cell_migration0.90844869
86MP0010770_preweaning_lethality0.90036564
87MP0002082_postnatal_lethality0.90036564
88MP0002069_abnormal_eating/drinking_beha0.90020828
89MP0002067_abnormal_sensory_capabilities0.89852202
90MP0002081_perinatal_lethality0.89736612
91MP0009840_abnormal_foam_cell0.89297585
92MP0002638_abnormal_pupillary_reflex0.88112673
93MP0001529_abnormal_vocalization0.87262464
94MP0009053_abnormal_anal_canal0.87144075
95MP0003119_abnormal_digestive_system0.87049758
96MP0001849_ear_inflammation0.86868850
97MP0000534_abnormal_ureter_morphology0.86759153
98MP0009672_abnormal_birth_weight0.84445421
99MP0003172_abnormal_lysosome_physiology0.83690128
100MP0010769_abnormal_survival0.83428326
101MP0010768_mortality/aging0.80286974
102MP0000631_abnormal_neuroendocrine_gland0.79878199
103MP0003631_nervous_system_phenotype0.79834472
104MP0005332_abnormal_amino_acid0.79255825
105MP0003890_abnormal_embryonic-extraembry0.78081340
106MP0001943_abnormal_respiration0.77296074
107MP0001986_abnormal_taste_sensitivity0.77013159
108MP0001299_abnormal_eye_distance/0.76820096
109MP0001502_abnormal_circadian_rhythm0.76742908
110MP0001177_atelectasis0.76644141
111MP0004130_abnormal_muscle_cell0.76607237
112MP0002118_abnormal_lipid_homeostasis0.75153130
113MP0003938_abnormal_ear_development0.74810094
114MP0003868_abnormal_feces_composition0.71873045
115MP0004142_abnormal_muscle_tone0.71572934
116MP0000003_abnormal_adipose_tissue0.70804458
117MP0000920_abnormal_myelination0.68525626
118MP0005499_abnormal_olfactory_system0.68366008
119MP0005394_taste/olfaction_phenotype0.68366008
120MP0000371_diluted_coat_color0.68206639
121MP0002089_abnormal_postnatal_growth/wei0.67809801
122MP0001984_abnormal_olfaction0.67605368
123MP0005448_abnormal_energy_balance0.67274366
124MP0003866_abnormal_defecation0.65907722
125MP0005646_abnormal_pituitary_gland0.65540198
126MP0002234_abnormal_pharynx_morphology0.65479581
127MP0001270_distended_abdomen0.64773757
128MP0003633_abnormal_nervous_system0.64714561
129MP0005666_abnormal_adipose_tissue0.64441116
130MP0003656_abnormal_erythrocyte_physiolo0.64057764
131MP0003942_abnormal_urinary_system0.63569412
132MP0000462_abnormal_digestive_system0.63275965
133MP0003115_abnormal_respiratory_system0.63264332
134MP0000609_abnormal_liver_physiology0.63051165
135MP0008874_decreased_physiological_sensi0.62689188
136MP0001501_abnormal_sleep_pattern0.61719734

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)3.64616549
2Abnormality of the lower motor neuron (HP:0002366)3.39749316
3Deep venous thrombosis (HP:0002625)3.25463997
4Hyperventilation (HP:0002883)3.11813366
5Focal seizures (HP:0007359)3.07755696
6Insidious onset (HP:0003587)3.06201318
7Termporal pattern (HP:0011008)3.06201318
8Asymmetry of the thorax (HP:0001555)2.93458747
9Urinary urgency (HP:0000012)2.88700767
10Supranuclear gaze palsy (HP:0000605)2.86109361
11Abnormality of the corticospinal tract (HP:0002492)2.85442774
12Focal motor seizures (HP:0011153)2.83555833
13Hyperacusis (HP:0010780)2.77026412
14Abnormal eating behavior (HP:0100738)2.73566893
15Impaired vibration sensation in the lower limbs (HP:0002166)2.72299625
16Insomnia (HP:0100785)2.72165629
17Spastic gait (HP:0002064)2.72115944
18Ankle clonus (HP:0011448)2.68786332
19Cerebral inclusion bodies (HP:0100314)2.63644526
20Deep palmar crease (HP:0006191)2.60324754
21Elfin facies (HP:0004428)2.58635811
22Abnormality of glutamine family amino acid metabolism (HP:0010902)2.57349285
23Flat acetabular roof (HP:0003180)2.54010486
24Macroorchidism (HP:0000053)2.53450111
25Renovascular hypertension (HP:0100817)2.52823923
26Urinary bladder sphincter dysfunction (HP:0002839)2.51719823
27Action tremor (HP:0002345)2.51451074
28Abnormal social behavior (HP:0012433)2.51270002
29Impaired social interactions (HP:0000735)2.51270002
30Hypobetalipoproteinemia (HP:0003563)2.50320155
31Cortical dysplasia (HP:0002539)2.49007043
32Turricephaly (HP:0000262)2.46969334
33Amyotrophic lateral sclerosis (HP:0007354)2.43327154
34Failure to thrive in infancy (HP:0001531)2.42306856
35Intrahepatic cholestasis (HP:0001406)2.41350142
36Visual hallucinations (HP:0002367)2.40844842
37Hypoplasia of the brainstem (HP:0002365)2.38212122
38Aplasia/Hypoplasia of the brainstem (HP:0007362)2.38212122
39High anterior hairline (HP:0009890)2.27346106
40Germ cell neoplasia (HP:0100728)2.27203433
41Poor eye contact (HP:0000817)2.26378594
42Xanthomatosis (HP:0000991)2.26161218
43Epidermoid cyst (HP:0200040)2.23905917
44Drooling (HP:0002307)2.23263913
45Excessive salivation (HP:0003781)2.23263913
46Clonus (HP:0002169)2.23037373
47Morphological abnormality of the pyramidal tract (HP:0002062)2.22991042
48Intention tremor (HP:0002080)2.17131666
49Pointed chin (HP:0000307)2.16984172
50Overriding aorta (HP:0002623)2.16310243
51Papilledema (HP:0001085)2.14711013
52Atonic seizures (HP:0010819)2.13582194
53Shawl scrotum (HP:0000049)2.13170355
54Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.12979834
55Absence seizures (HP:0002121)2.11215715
56Menstrual irregularities (HP:0000858)2.08390209
57Renal duplication (HP:0000075)2.07740554
58Neurofibrillary tangles (HP:0002185)2.06903819
59Lower limb muscle weakness (HP:0007340)2.05746331
60Thickened helices (HP:0000391)2.05609301
61Dysmetric saccades (HP:0000641)2.05283614
62Abnormality of monocarboxylic acid metabolism (HP:0010996)2.04978439
63Status epilepticus (HP:0002133)2.03700989
64Neonatal hypoglycemia (HP:0001998)2.03609800
65Skin nodule (HP:0200036)2.02668083
66Megalencephaly (HP:0001355)2.02664486
67Long clavicles (HP:0000890)2.01564242
68Torticollis (HP:0000473)2.00939378
69Abnormality of the fingertips (HP:0001211)1.99717002
70Hepatoblastoma (HP:0002884)1.99501935
71Lower limb asymmetry (HP:0100559)1.99072821
72Buphthalmos (HP:0000557)1.98742600
73Progressive cerebellar ataxia (HP:0002073)1.97273829
74Pseudobulbar signs (HP:0002200)1.97096223
75Truncal ataxia (HP:0002078)1.94728381
76Spastic paraplegia (HP:0001258)1.94716669
77Epileptic encephalopathy (HP:0200134)1.92879612
78Exotropia (HP:0000577)1.91198706
79Smooth philtrum (HP:0000319)1.90439116
80Overlapping toe (HP:0001845)1.90354175
81Open mouth (HP:0000194)1.90155312
82Amblyopia (HP:0000646)1.89438574
83Heterotopia (HP:0002282)1.88971445
84Partial agenesis of the corpus callosum (HP:0001338)1.88725202
85Alacrima (HP:0000522)1.88515082
86Paraplegia (HP:0010550)1.88023872
87Lymphangioma (HP:0100764)1.87869172
88Hypoplasia of the corpus callosum (HP:0002079)1.86820281
89Hydroxyprolinuria (HP:0003080)1.86042314
90Abnormality of proline metabolism (HP:0010907)1.86042314
91Subacute progressive viral hepatitis (HP:0006572)1.84216148
92Broad-based gait (HP:0002136)1.83833922
93Dysmetria (HP:0001310)1.83133717
94Distal upper limb amyotrophy (HP:0007149)1.82481443
95Upper limb amyotrophy (HP:0009129)1.82481443
96Hemiplegia (HP:0002301)1.82231198
97Hypsarrhythmia (HP:0002521)1.81292201
98Protruding tongue (HP:0010808)1.80110367
99Abnormality of aromatic amino acid family metabolism (HP:0004338)1.80092375
100Hand muscle atrophy (HP:0009130)1.79937668
101Disproportionate tall stature (HP:0001519)1.79574889
102Growth hormone excess (HP:0000845)1.78274981
103Uterine leiomyosarcoma (HP:0002891)1.77593159
104Leiomyosarcoma (HP:0100243)1.77593159
105Colitis (HP:0002583)1.77284242
106Megalocornea (HP:0000485)1.76580419
107Generalized tonic-clonic seizures (HP:0002069)1.75719995
108EEG with generalized epileptiform discharges (HP:0011198)1.75189598
109Hammertoe (HP:0001765)1.74728389
110Depression (HP:0000716)1.74600391
111Abnormality of the intervertebral disk (HP:0005108)1.74388960
112Back pain (HP:0003418)1.74253824
113Curly hair (HP:0002212)1.74154104
114Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.73606885
115Degeneration of the lateral corticospinal tracts (HP:0002314)1.73606885
116Genetic anticipation (HP:0003743)1.73334345
117Transitional cell carcinoma of the bladder (HP:0006740)1.73301084
118Papillary thyroid carcinoma (HP:0002895)1.73051435
119Spastic diplegia (HP:0001264)1.72736293
120Complement deficiency (HP:0004431)1.72252393
121Peripheral hypomyelination (HP:0007182)1.72166158
122Abnormality of the distal phalanx of the thumb (HP:0009617)1.71935177
123Scanning speech (HP:0002168)1.71558785
124Sacral dimple (HP:0000960)1.71281837
125Aqueductal stenosis (HP:0002410)1.71159541
126Neonatal onset (HP:0003623)1.71135510
127Impulsivity (HP:0100710)1.70972279
128Spastic tetraplegia (HP:0002510)1.70888857
129Abnormality of the gastric mucosa (HP:0004295)1.70327712
130Ankyloglossia (HP:0010296)1.70058164
131Patellar dislocation (HP:0002999)1.69747158
132Dialeptic seizures (HP:0011146)1.69018795
133Epileptiform EEG discharges (HP:0011182)1.68966786
134Abnormality of the periventricular white matter (HP:0002518)1.68713259
135Gout (HP:0001997)1.68662986
136Obsessive-compulsive behavior (HP:0000722)1.68488713
137Polyphagia (HP:0002591)1.68414424
138Cubitus valgus (HP:0002967)1.67996311
139Focal dystonia (HP:0004373)1.67157574
140Obstructive sleep apnea (HP:0002870)1.67145279
141Long toe (HP:0010511)1.65972793
142Hepatocellular carcinoma (HP:0001402)1.65888385
143Bladder neoplasm (HP:0009725)1.65693709
144Bladder carcinoma (HP:0002862)1.65693709
145Broad palm (HP:0001169)1.65674632
146Abnormality of the sella turcica (HP:0002679)1.65266375
147Blue irides (HP:0000635)1.65206247
148Trigonocephaly (HP:0000243)1.65047099
149Viral hepatitis (HP:0006562)1.64777726
150Vertebral arch anomaly (HP:0008438)1.64060011
151Prominent forehead (HP:0011220)1.63544412
152Abnormality of chromosome segregation (HP:0002916)1.63541339
153Febrile seizures (HP:0002373)1.63412367
154Thick eyebrow (HP:0000574)1.63064663
155Visceral angiomatosis (HP:0100761)1.60884625
156Hemangiomatosis (HP:0007461)1.60606829
157Abnormality of salivation (HP:0100755)1.60044446

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K93.98499729
2CASK3.44634852
3MARK13.32924843
4EPHA32.65621172
5NTRK32.42838917
6PAK62.31444578
7KSR12.31040874
8MINK12.20952796
9KSR22.12846280
10ICK2.04653009
11MAP3K42.03697724
12RIPK12.02413794
13FGFR21.77348134
14PRKD31.69061173
15TRIB31.68277736
16MAP3K131.68116834
17BCR1.65781868
18TYRO31.57370448
19SIK21.57114001
20EPHA41.55461793
21MAP2K41.54236643
22LATS21.54045306
23UHMK11.45423329
24DAPK21.45012604
25SGK21.41104196
26SCYL21.39823786
27NTRK11.37959188
28NTRK21.37915892
29PAK31.32919440
30PTK61.29075918
31RET1.28954541
32PDGFRA1.27132532
33SMG11.27108947
34MARK21.25835359
35MAPK111.20942517
36AKT31.18410921
37NEK11.17862687
38ERN11.17808858
39ERBB21.14512216
40CDK51.13929793
41BMX1.13369825
42CAMKK11.06358841
43PRPF4B1.05469393
44SIK31.04126376
45CDK121.02803994
46SIK11.00456396
47FGFR40.99497676
48CAMK1G0.97709537
49MAP3K20.97355261
50PRKCZ0.97039952
51RPS6KA20.93192381
52CLK10.90919392
53DDR20.89784456
54MAP3K100.88590767
55ALK0.87406878
56PTK20.86698926
57PIK3CA0.82504359
58TESK10.82373900
59WNK10.79987320
60MAP3K70.79339852
61RPS6KB10.73851681
62PKN20.73221536
63YES10.73219752
64CAMK40.72805662
65SGK30.72279584
66LIMK10.71549863
67SGK2230.71321937
68SGK4940.71321937
69CSNK1G20.70606468
70MAPK130.69722332
71FRK0.69538209
72MAP3K140.69534491
73SRPK10.68714377
74STK110.68476110
75CDK180.68335295
76EPHB20.68286790
77TNIK0.68184769
78MAP2K20.68093636
79PRKCH0.65994681
80STK380.64761563
81CDK150.62347828
82FGFR10.62251426
83PKN10.61530816
84CDK140.60369098
85MAP3K60.59857077
86CSNK1A1L0.59638842
87PDK10.59523743
88FER0.59485202
89CDC42BPA0.59270490
90EEF2K0.59138467
91BRD40.58906352
92LMTK20.58619745
93MTOR0.58515722
94CAMK1D0.58505711
95JAK20.58400582
96ROCK10.57655345
97RPS6KB20.57383292
98ERBB30.57004507
99JAK10.56583356
100ROCK20.56479424
101MAP2K10.54052220
102FGFR30.53697881
103SGK10.52861125
104MAP2K70.52251733
105PHKG20.50587389
106PHKG10.50587389
107DAPK10.50511080
108IRAK20.50152764
109DYRK1B0.48052254
110DYRK20.47996826
111PDPK10.46991423
112PRKCG0.46767077
113GSK3B0.46336573
114NEK60.46107341
115MAPK80.45417502
116CDK40.44874785
117CDK11A0.44811852
118PDGFRB0.44467195
119FYN0.44308044
120WNK30.43862520
121PRKAA10.43343059
122RPS6KA30.43322561
123RIPK40.42611411
124OXSR10.42607524
125MAPK100.42261623
126CDK20.41636644
127LATS10.41365235
128CSNK1D0.41029053
129CDK60.40665389
130PASK0.40594310
131DYRK1A0.38317022
132CHUK0.36156234
133CDK30.36134112
134MAPK120.35689224
135CDK10.34601236
136MAPK140.34288267
137PRKDC0.34265933
138MAPK90.32909512

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.61839614
2Nitrogen metabolism_Homo sapiens_hsa009103.28609778
3Arginine biosynthesis_Homo sapiens_hsa002202.40464856
4Primary bile acid biosynthesis_Homo sapiens_hsa001202.01970638
5Bile secretion_Homo sapiens_hsa049761.80466148
6Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.74938264
7B cell receptor signaling pathway_Homo sapiens_hsa046621.74658218
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.69798418
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.68923707
10Butanoate metabolism_Homo sapiens_hsa006501.67654569
11Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.63946233
12Synaptic vesicle cycle_Homo sapiens_hsa047211.63391039
13Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.53560177
14Axon guidance_Homo sapiens_hsa043601.52892027
15GABAergic synapse_Homo sapiens_hsa047271.49126234
16Nicotine addiction_Homo sapiens_hsa050331.38794626
17Type II diabetes mellitus_Homo sapiens_hsa049301.36244171
18Long-term potentiation_Homo sapiens_hsa047201.32602649
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.32059395
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.31334830
21Circadian entrainment_Homo sapiens_hsa047131.27443586
22Glutamatergic synapse_Homo sapiens_hsa047241.26008026
23Tryptophan metabolism_Homo sapiens_hsa003801.25432554
24Pancreatic cancer_Homo sapiens_hsa052121.24485267
25Dopaminergic synapse_Homo sapiens_hsa047281.21526826
26Acute myeloid leukemia_Homo sapiens_hsa052211.19869881
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.14833940
28Fat digestion and absorption_Homo sapiens_hsa049751.13451190
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.11917600
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.10479381
31Endometrial cancer_Homo sapiens_hsa052131.06676626
32Alcoholism_Homo sapiens_hsa050341.05742194
33* Inositol phosphate metabolism_Homo sapiens_hsa005621.05243546
34Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.04926936
35Gastric acid secretion_Homo sapiens_hsa049711.04628328
36Cholinergic synapse_Homo sapiens_hsa047251.04148446
37Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.03821464
38Fatty acid biosynthesis_Homo sapiens_hsa000611.02720685
39Morphine addiction_Homo sapiens_hsa050321.02297263
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.01737799
41Glioma_Homo sapiens_hsa052141.00963106
42Estrogen signaling pathway_Homo sapiens_hsa049151.00033177
43Amphetamine addiction_Homo sapiens_hsa050310.99614572
44Prostate cancer_Homo sapiens_hsa052150.99019125
45ErbB signaling pathway_Homo sapiens_hsa040120.98908622
46Salivary secretion_Homo sapiens_hsa049700.97912834
47Olfactory transduction_Homo sapiens_hsa047400.97662389
48Gap junction_Homo sapiens_hsa045400.97453746
49Insulin secretion_Homo sapiens_hsa049110.97125597
50Dorso-ventral axis formation_Homo sapiens_hsa043200.96356601
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91030143
522-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.90506015
53GnRH signaling pathway_Homo sapiens_hsa049120.88301054
54Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88132715
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.85683513
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84134152
57FoxO signaling pathway_Homo sapiens_hsa040680.83824901
58Renin secretion_Homo sapiens_hsa049240.81885051
59MicroRNAs in cancer_Homo sapiens_hsa052060.81718571
60PPAR signaling pathway_Homo sapiens_hsa033200.81375811
61Cocaine addiction_Homo sapiens_hsa050300.80504067
62Hepatitis B_Homo sapiens_hsa051610.79692228
63Oxytocin signaling pathway_Homo sapiens_hsa049210.79511494
64VEGF signaling pathway_Homo sapiens_hsa043700.79288992
65Lysine degradation_Homo sapiens_hsa003100.78773505
66mTOR signaling pathway_Homo sapiens_hsa041500.77942574
67Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77248671
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.75206562
69Notch signaling pathway_Homo sapiens_hsa043300.73485052
70Thyroid cancer_Homo sapiens_hsa052160.73461321
71Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73062010
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71599275
73Thyroid hormone synthesis_Homo sapiens_hsa049180.71401171
74Steroid hormone biosynthesis_Homo sapiens_hsa001400.70908807
75Caffeine metabolism_Homo sapiens_hsa002320.70589189
76Sphingolipid signaling pathway_Homo sapiens_hsa040710.69926394
77Complement and coagulation cascades_Homo sapiens_hsa046100.69317775
78Long-term depression_Homo sapiens_hsa047300.69014687
79T cell receptor signaling pathway_Homo sapiens_hsa046600.66505781
80Prion diseases_Homo sapiens_hsa050200.66070895
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65892814
82* Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65846625
83mRNA surveillance pathway_Homo sapiens_hsa030150.65694476
84Fatty acid degradation_Homo sapiens_hsa000710.65030963
85Systemic lupus erythematosus_Homo sapiens_hsa053220.64901244
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64638852
87Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64479732
88Non-small cell lung cancer_Homo sapiens_hsa052230.64391439
89Melanogenesis_Homo sapiens_hsa049160.64295096
90HIF-1 signaling pathway_Homo sapiens_hsa040660.64100143
91Viral carcinogenesis_Homo sapiens_hsa052030.63789948
92Renal cell carcinoma_Homo sapiens_hsa052110.63354058
93Vitamin B6 metabolism_Homo sapiens_hsa007500.63102140
94Hepatitis C_Homo sapiens_hsa051600.61131110
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.61060973
96Insulin signaling pathway_Homo sapiens_hsa049100.61043718
97Insulin resistance_Homo sapiens_hsa049310.61024825
98AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59188464
99Glucagon signaling pathway_Homo sapiens_hsa049220.58918013
100Fatty acid metabolism_Homo sapiens_hsa012120.58855405
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58803654
102Hippo signaling pathway_Homo sapiens_hsa043900.57204668
103Phospholipase D signaling pathway_Homo sapiens_hsa040720.55122506
104Prolactin signaling pathway_Homo sapiens_hsa049170.55043945
105ABC transporters_Homo sapiens_hsa020100.54950616
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54474052
107AMPK signaling pathway_Homo sapiens_hsa041520.53743939
108Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.53580498
109Rap1 signaling pathway_Homo sapiens_hsa040150.52828775
110Choline metabolism in cancer_Homo sapiens_hsa052310.52412132
111cAMP signaling pathway_Homo sapiens_hsa040240.51762500
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50740954
113Cyanoamino acid metabolism_Homo sapiens_hsa004600.49623836
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.48830265
115Phenylalanine metabolism_Homo sapiens_hsa003600.48582711
116Proteoglycans in cancer_Homo sapiens_hsa052050.47111263
117Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46224406
118Endocytosis_Homo sapiens_hsa041440.46179916
119cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45580448
120MAPK signaling pathway_Homo sapiens_hsa040100.45432406
121Colorectal cancer_Homo sapiens_hsa052100.45218610
122Adipocytokine signaling pathway_Homo sapiens_hsa049200.44910373
123Chronic myeloid leukemia_Homo sapiens_hsa052200.44852147
124Tight junction_Homo sapiens_hsa045300.43996833
125Oocyte meiosis_Homo sapiens_hsa041140.43486237
126Jak-STAT signaling pathway_Homo sapiens_hsa046300.43068172
127Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42772587
128Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42504630
129Taste transduction_Homo sapiens_hsa047420.41954470
130Serotonergic synapse_Homo sapiens_hsa047260.38708556
131Biosynthesis of amino acids_Homo sapiens_hsa012300.37658172
132Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37644477

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