MSH2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.77049689
2DNA replication initiation (GO:0006270)5.02560371
3DNA strand elongation involved in DNA replication (GO:0006271)5.01407285
4DNA strand elongation (GO:0022616)4.75942053
5nuclear pore organization (GO:0006999)4.73921951
6DNA replication-dependent nucleosome assembly (GO:0006335)4.62980404
7DNA replication-dependent nucleosome organization (GO:0034723)4.62980404
8protein localization to kinetochore (GO:0034501)4.54926883
9telomere maintenance via semi-conservative replication (GO:0032201)4.47032239
10nuclear pore complex assembly (GO:0051292)4.46805592
11IMP biosynthetic process (GO:0006188)4.25396077
12nucleobase biosynthetic process (GO:0046112)4.25076926
13formation of translation preinitiation complex (GO:0001731)4.16723080
14mitotic nuclear envelope disassembly (GO:0007077)4.15054118
15DNA replication checkpoint (GO:0000076)4.07178238
16DNA duplex unwinding (GO:0032508)4.02544675
17DNA geometric change (GO:0032392)4.01987877
18regulation of gene silencing by miRNA (GO:0060964)4.01676300
19regulation of gene silencing by RNA (GO:0060966)4.01676300
20regulation of posttranscriptional gene silencing (GO:0060147)4.01676300
21telomere maintenance via recombination (GO:0000722)3.98570612
22mitotic recombination (GO:0006312)3.98416550
23mitotic metaphase plate congression (GO:0007080)3.98271795
24folic acid-containing compound biosynthetic process (GO:0009396)3.97014109
25establishment of viral latency (GO:0019043)3.96334672
26maturation of SSU-rRNA (GO:0030490)3.90097123
27membrane disassembly (GO:0030397)3.87147600
28nuclear envelope disassembly (GO:0051081)3.87147600
29DNA double-strand break processing (GO:0000729)3.86032929
30purine nucleobase biosynthetic process (GO:0009113)3.85246419
31double-strand break repair via nonhomologous end joining (GO:0006303)3.85219171
32non-recombinational repair (GO:0000726)3.85219171
33protein localization to chromosome, centromeric region (GO:0071459)3.80167839
34DNA ligation (GO:0006266)3.73748346
35IMP metabolic process (GO:0046040)3.73064686
36telomere maintenance via telomere lengthening (GO:0010833)3.71953643
37mitotic chromosome condensation (GO:0007076)3.68780175
38metaphase plate congression (GO:0051310)3.67348412
39L-serine metabolic process (GO:0006563)3.66814570
40mitotic sister chromatid segregation (GO:0000070)3.65505373
41negative regulation of DNA-dependent DNA replication (GO:2000104)3.61958473
42regulation of histone H3-K9 methylation (GO:0051570)3.61518387
43nucleotide-excision repair, DNA gap filling (GO:0006297)3.59812549
44chromatin remodeling at centromere (GO:0031055)3.59369830
45ribosomal small subunit assembly (GO:0000028)3.56805288
46regulation of centriole replication (GO:0046599)3.50134164
47ATP-dependent chromatin remodeling (GO:0043044)3.48679437
48negative regulation of histone methylation (GO:0031061)3.48630065
49kinetochore organization (GO:0051383)3.48483160
50ribosome assembly (GO:0042255)3.48010805
51pore complex assembly (GO:0046931)3.47945841
52sister chromatid segregation (GO:0000819)3.46985822
53CENP-A containing nucleosome assembly (GO:0034080)3.45680784
54regulation of mitotic sister chromatid separation (GO:0010965)3.44420294
55regulation of mitotic sister chromatid segregation (GO:0033047)3.44420294
56regulation of sister chromatid segregation (GO:0033045)3.44420294
57DNA replication-independent nucleosome assembly (GO:0006336)3.43151317
58DNA replication-independent nucleosome organization (GO:0034724)3.43151317
59heterochromatin organization (GO:0070828)3.42247111
60regulation of mitotic spindle checkpoint (GO:1903504)3.42221906
61regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.42221906
62ribosome biogenesis (GO:0042254)3.41747327
63attachment of spindle microtubules to kinetochore (GO:0008608)3.40173596
64regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.36326344
65pre-miRNA processing (GO:0031054)3.32737709
66* somatic diversification of immune receptors via somatic mutation (GO:0002566)3.32040260
67* somatic hypermutation of immunoglobulin genes (GO:0016446)3.32040260
68regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.31888335
69protein complex localization (GO:0031503)3.31404547
70establishment of chromosome localization (GO:0051303)3.27474872
71establishment of integrated proviral latency (GO:0075713)3.26493692
72DNA topological change (GO:0006265)3.26379023
73mitotic sister chromatid cohesion (GO:0007064)3.24125735
74DNA conformation change (GO:0071103)3.23264381
75negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.22686897
76negative regulation of chromosome segregation (GO:0051985)3.22286945
77ribonucleoprotein complex biogenesis (GO:0022613)3.19185308
78DNA catabolic process, exonucleolytic (GO:0000738)3.18916432
79protein K6-linked ubiquitination (GO:0085020)3.18627666
80regulation of spindle organization (GO:0090224)3.18574256
81positive regulation of chromosome segregation (GO:0051984)3.18185747
82replication fork processing (GO:0031297)3.18049060
83regulation of nuclear cell cycle DNA replication (GO:0033262)3.16325507
84chromatin assembly or disassembly (GO:0006333)3.16115087
85negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.15676022
86negative regulation of sister chromatid segregation (GO:0033046)3.15676022
87negative regulation of mitotic sister chromatid separation (GO:2000816)3.15676022
88negative regulation of mitotic sister chromatid segregation (GO:0033048)3.15676022
89DNA strand renaturation (GO:0000733)3.15067706
90regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.14444307
91spindle assembly checkpoint (GO:0071173)3.14125920
92regulation of chromosome segregation (GO:0051983)3.12666926
93viral transcription (GO:0019083)3.12475481
94translational termination (GO:0006415)3.11530394
95regulation of centrosome cycle (GO:0046605)3.11477302
96ribosomal large subunit biogenesis (GO:0042273)3.11060572
97negative regulation of mitosis (GO:0045839)3.10966581
98mitotic spindle assembly checkpoint (GO:0007094)3.10948730
99spindle checkpoint (GO:0031577)3.09300534
100base-excision repair (GO:0006284)3.09060200
101translesion synthesis (GO:0019985)3.09050973
102kinetochore assembly (GO:0051382)3.08825671
103mitotic G2/M transition checkpoint (GO:0044818)3.08723316
104chromatin assembly (GO:0031497)3.08376263
105regulation of sister chromatid cohesion (GO:0007063)3.07383691
106histone exchange (GO:0043486)3.07326894
107negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.06316945
108negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.06230429
109regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.05873366
110telomere maintenance (GO:0000723)3.04426304
111regulation of translational fidelity (GO:0006450)3.04062799
112mitotic spindle checkpoint (GO:0071174)3.03852858
113telomere organization (GO:0032200)3.03618661
114proteasome assembly (GO:0043248)3.03167553
115regulation of mitotic metaphase/anaphase transition (GO:0030071)3.03164032
116translational initiation (GO:0006413)3.01316434
117anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.98537756
118meiotic chromosome segregation (GO:0045132)2.98504855
119maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.98355520
120dosage compensation (GO:0007549)2.97530021
121nuclear envelope organization (GO:0006998)2.97443723
122regulation of DNA endoreduplication (GO:0032875)2.96949477
123* mismatch repair (GO:0006298)2.96592846
124peptidyl-arginine omega-N-methylation (GO:0035247)2.96405107
125regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.96149528
126regulation of double-strand break repair via homologous recombination (GO:0010569)2.95799170
127histone arginine methylation (GO:0034969)2.95123279
128DNA damage response, detection of DNA damage (GO:0042769)2.94613382
129negative regulation of mRNA processing (GO:0050686)2.94095044

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* E2F7_22180533_ChIP-Seq_HELA_Human9.94734802
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.32295818
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.19000805
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.90823649
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.26349947
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.14009211
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.12324055
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.79753886
9MYC_18358816_ChIP-ChIP_MESCs_Mouse2.58834367
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.39631404
11* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35475152
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.30826576
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.29664627
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.24134782
15* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.22911777
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.18913593
17XRN2_22483619_ChIP-Seq_HELA_Human2.17756343
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17325292
19MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.10690300
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.10195570
21JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.09433708
22* E2F1_21310950_ChIP-Seq_MCF-7_Human2.08166606
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.07348624
24SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.03723158
25GABP_17652178_ChIP-ChIP_JURKAT_Human2.02999538
26AR_21909140_ChIP-Seq_LNCAP_Human2.02163010
27POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.00284208
28NANOG_18555785_ChIP-Seq_MESCs_Mouse1.99669736
29* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.93580761
30* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.88631354
31* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.87592959
32VDR_23849224_ChIP-Seq_CD4+_Human1.85042047
33KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.82204915
34KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.82204915
35KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.82204915
36MYC_22102868_ChIP-Seq_BL_Human1.75237447
37FOXP3_21729870_ChIP-Seq_TREG_Human1.73316351
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.68440091
39TTF2_22483619_ChIP-Seq_HELA_Human1.65539146
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.64471622
41CIITA_25753668_ChIP-Seq_RAJI_Human1.63485168
42SOX2_18555785_ChIP-Seq_MESCs_Mouse1.62285999
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62036025
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60620893
45POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.58051713
46GABP_19822575_ChIP-Seq_HepG2_Human1.56656284
47DCP1A_22483619_ChIP-Seq_HELA_Human1.56507727
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53250937
49NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53014868
50POU5F1_16153702_ChIP-ChIP_HESCs_Human1.51068413
51STAT3_1855785_ChIP-Seq_MESCs_Mouse1.50978783
52* NANOG_16153702_ChIP-ChIP_HESCs_Human1.49904352
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.48580600
54SOX2_16153702_ChIP-ChIP_HESCs_Human1.48282433
55ELF1_17652178_ChIP-ChIP_JURKAT_Human1.46261262
56NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.41623431
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.41366102
58* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.38957667
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38593497
60MYC_18940864_ChIP-ChIP_HL60_Human1.37888436
61KDM5A_27292631_Chip-Seq_BREAST_Human1.37425897
62YY1_21170310_ChIP-Seq_MESCs_Mouse1.36172279
63SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.35293068
64* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.34957856
65ELK1_19687146_ChIP-ChIP_HELA_Human1.33373392
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32610240
67NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.32591962
68ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.30950334
69E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.29716686
70PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.29713688
71HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.28648690
72RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25688085
73* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25677710
74ESR1_15608294_ChIP-ChIP_MCF-7_Human1.25504901
75KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.24431927
76HOXB4_20404135_ChIP-ChIP_EML_Mouse1.22443796
77FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20925534
78EWS_26573619_Chip-Seq_HEK293_Human1.19925384
79* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.18157076
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.18006998
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13931916
82FUS_26573619_Chip-Seq_HEK293_Human1.12067341
83NANOG_21062744_ChIP-ChIP_HESCs_Human1.11781641
84TFEB_21752829_ChIP-Seq_HELA_Human1.11200380
85SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.10400086
86CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07193689
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06665352
88E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06619456
89* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.06050528
90ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05488424
91PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05146960
92NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.04569760
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02752253
94ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98543312
95* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.98223069
96SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.97733366
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96585723
98* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.96250827
99* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95454201
100SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94826157
101HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.94376282
102ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93933516
103* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.92880402
104* SOX17_20123909_ChIP-Seq_XEN_Mouse0.91949129
105SRF_21415370_ChIP-Seq_HL-1_Mouse0.91051327
106IRF1_19129219_ChIP-ChIP_H3396_Human0.90620355
107SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.89243068
108HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.88298084
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.84291787
110* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.84058326
111* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.83626468
112ZNF274_21170338_ChIP-Seq_K562_Hela0.82470348
113ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.80794088
114DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.78943359
115TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.74483152
116CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74091568
117NOTCH1_21737748_ChIP-Seq_TLL_Human0.71111161
118FLI1_27457419_Chip-Seq_LIVER_Mouse0.69944957
119IGF1R_20145208_ChIP-Seq_DFB_Human0.69525094
120CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.68023925

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.09988135
2MP0003693_abnormal_embryo_hatching5.03754865
3MP0003111_abnormal_nucleus_morphology4.59565619
4MP0004957_abnormal_blastocyst_morpholog4.43734164
5MP0008057_abnormal_DNA_replication4.32972063
6* MP0003077_abnormal_cell_cycle4.00787018
7* MP0008058_abnormal_DNA_repair3.17082529
8MP0008007_abnormal_cellular_replicative2.78071781
9MP0003123_paternal_imprinting2.72869164
10MP0001730_embryonic_growth_arrest2.59172508
11MP0008932_abnormal_embryonic_tissue2.56665267
12MP0000350_abnormal_cell_proliferation2.48532626
13MP0008877_abnormal_DNA_methylation2.47975491
14MP0002396_abnormal_hematopoietic_system2.12508280
15MP0009697_abnormal_copulation2.10518791
16MP0005380_embryogenesis_phenotype2.00185861
17MP0001672_abnormal_embryogenesis/_devel2.00185861
18MP0003786_premature_aging1.93610367
19MP0003890_abnormal_embryonic-extraembry1.93128194
20MP0001697_abnormal_embryo_size1.93053134
21MP0003121_genomic_imprinting1.91310991
22MP0002084_abnormal_developmental_patter1.90562576
23MP0002085_abnormal_embryonic_tissue1.89221662
24* MP0010352_gastrointestinal_tract_polyps1.78503250
25MP0004197_abnormal_fetal_growth/weight/1.77586424
26MP0003984_embryonic_growth_retardation1.75283342
27MP0002080_prenatal_lethality1.74854691
28MP0002088_abnormal_embryonic_growth/wei1.72612891
29MP0002086_abnormal_extraembryonic_tissu1.69244748
30MP0004133_heterotaxia1.67675138
31* MP0010307_abnormal_tumor_latency1.65121255
32MP0000490_abnormal_crypts_of1.62950296
33MP0001293_anophthalmia1.57310671
34MP0005076_abnormal_cell_differentiation1.52077822
35MP0003806_abnormal_nucleotide_metabolis1.49768331
36MP0002653_abnormal_ependyma_morphology1.47518370
37MP0010030_abnormal_orbit_morphology1.47191748
38* MP0000313_abnormal_cell_death1.46032935
39MP0003567_abnormal_fetal_cardiomyocyte1.43809607
40MP0004808_abnormal_hematopoietic_stem1.42253424
41MP0006035_abnormal_mitochondrial_morpho1.41905900
42MP0000537_abnormal_urethra_morphology1.40116411
43MP0001188_hyperpigmentation1.37623927
44* MP0002019_abnormal_tumor_incidence1.37423066
45MP0003119_abnormal_digestive_system1.35546962
46MP0006292_abnormal_olfactory_placode1.32200431
47MP0002210_abnormal_sex_determination1.31417638
48MP0002254_reproductive_system_inflammat1.27759021
49MP0001529_abnormal_vocalization1.25996824
50MP0003315_abnormal_perineum_morphology1.25674728
51MP0002938_white_spotting1.23158226
52MP0001145_abnormal_male_reproductive1.20191388
53MP0003718_maternal_effect1.18891280
54MP0002233_abnormal_nose_morphology1.15912076
55MP0008789_abnormal_olfactory_epithelium1.08989197
56MP0004264_abnormal_extraembryonic_tissu1.08118228
57MP0000703_abnormal_thymus_morphology1.07459059
58MP0000579_abnormal_nail_morphology1.06206333
59MP0002102_abnormal_ear_morphology1.05438486
60MP0003283_abnormal_digestive_organ1.02648035
61MP0003136_yellow_coat_color1.01524648
62MP0001177_atelectasis0.99828342
63MP0005499_abnormal_olfactory_system0.99199729
64MP0005394_taste/olfaction_phenotype0.99199729
65MP0003941_abnormal_skin_development0.98977197
66MP0002160_abnormal_reproductive_system0.98557702
67MP0001929_abnormal_gametogenesis0.98174673
68MP0000653_abnormal_sex_gland0.97068187
69MP0009672_abnormal_birth_weight0.96829145
70MP0001849_ear_inflammation0.96217659
71MP0009703_decreased_birth_body0.95225426
72MP0000049_abnormal_middle_ear0.94514195
73MP0002111_abnormal_tail_morphology0.94192879
74MP0009053_abnormal_anal_canal0.93464233
75MP0000566_synostosis0.91559135
76MP0003763_abnormal_thymus_physiology0.89927748
77MP0005397_hematopoietic_system_phenotyp0.89592818
78MP0001545_abnormal_hematopoietic_system0.89592818
79MP0003937_abnormal_limbs/digits/tail_de0.88670591
80MP0008995_early_reproductive_senescence0.87030575
81MP0002751_abnormal_autonomic_nervous0.86833787
82MP0003787_abnormal_imprinting0.83556828
83MP0000358_abnormal_cell_content/0.83474272
84MP0002092_abnormal_eye_morphology0.83085152
85MP0001286_abnormal_eye_development0.82489145
86MP0009278_abnormal_bone_marrow0.82124861
87* MP0005384_cellular_phenotype0.81705358
88MP0004147_increased_porphyrin_level0.81235194
89MP0005389_reproductive_system_phenotype0.80781877
90MP0002722_abnormal_immune_system0.80404630
91MP0001299_abnormal_eye_distance/0.79583585
92MP0003566_abnormal_cell_adhesion0.77205618
93MP0003122_maternal_imprinting0.76729546
94MP0000647_abnormal_sebaceous_gland0.76199404
95MP0003705_abnormal_hypodermis_morpholog0.75845418
96* MP0002398_abnormal_bone_marrow0.75573426
97MP0000428_abnormal_craniofacial_morphol0.75377439
98MP0003861_abnormal_nervous_system0.75206270
99MP0001119_abnormal_female_reproductive0.73773847
100MP0001915_intracranial_hemorrhage0.73477835
101* MP0005621_abnormal_cell_physiology0.72875314
102MP0005023_abnormal_wound_healing0.72587440
103MP0000689_abnormal_spleen_morphology0.71218286
104MP0009333_abnormal_splenocyte_physiolog0.71211643
105MP0002075_abnormal_coat/hair_pigmentati0.71038642
106MP0003755_abnormal_palate_morphology0.70316284
107MP0002796_impaired_skin_barrier0.69608629
108MP0002697_abnormal_eye_size0.68969790
109MP0005395_other_phenotype0.68875357
110MP0001346_abnormal_lacrimal_gland0.68479076
111MP0003698_abnormal_male_reproductive0.68410587
112* MP0000477_abnormal_intestine_morphology0.66875819
113MP0005391_vision/eye_phenotype0.66263295
114MP0006072_abnormal_retinal_apoptosis0.66065367
115MP0000432_abnormal_head_morphology0.65111129
116MP0006036_abnormal_mitochondrial_physio0.64227212
117MP0005075_abnormal_melanosome_morpholog0.63392634
118MP0000631_abnormal_neuroendocrine_gland0.63079045
119MP0003935_abnormal_craniofacial_develop0.63000545
120MP0000858_altered_metastatic_potential0.62936394
121MP0002161_abnormal_fertility/fecundity0.62302038
122MP0004233_abnormal_muscle_weight0.61410814
123MP0002081_perinatal_lethality0.61267761
124MP0005367_renal/urinary_system_phenotyp0.60792853
125MP0000516_abnormal_urinary_system0.60792853
126MP0002234_abnormal_pharynx_morphology0.60497016
127MP0003699_abnormal_female_reproductive0.60428476
128MP0000371_diluted_coat_color0.59898759
129MP0005266_abnormal_metabolism0.59826331
130MP0002090_abnormal_vision0.59019697
131MP0002925_abnormal_cardiovascular_devel0.58742632
132MP0005501_abnormal_skin_physiology0.58638435
133MP0003186_abnormal_redox_activity0.57390299
134MP0003115_abnormal_respiratory_system0.57001653
135MP0001919_abnormal_reproductive_system0.56702423
136MP0002114_abnormal_axial_skeleton0.55833056
137MP0003221_abnormal_cardiomyocyte_apopto0.55632415

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.52433212
2Chromsome breakage (HP:0040012)4.39893420
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.20239523
4* Ependymoma (HP:0002888)4.01019844
5* Medulloblastoma (HP:0002885)3.89317186
6Selective tooth agenesis (HP:0001592)3.69350202
7Reticulocytopenia (HP:0001896)3.66128457
8Abnormality of chromosome stability (HP:0003220)3.60675948
9Abnormality of the labia minora (HP:0012880)3.54768177
10Breast hypoplasia (HP:0003187)3.49143399
11Meckel diverticulum (HP:0002245)3.41131753
12Abnormality of the ileum (HP:0001549)3.30182923
13Aplasia/Hypoplasia of the uvula (HP:0010293)3.28525688
14Cortical dysplasia (HP:0002539)3.28184198
15Abnormality of the preputium (HP:0100587)3.24185259
16Patellar aplasia (HP:0006443)3.18075317
17Supernumerary spleens (HP:0009799)3.06408659
18Absent thumb (HP:0009777)3.02082757
19Oral leukoplakia (HP:0002745)3.01414487
20Absent radius (HP:0003974)2.96076262
21Abnormal number of incisors (HP:0011064)2.94514104
22Aplasia/Hypoplasia of the patella (HP:0006498)2.93842774
23Myelodysplasia (HP:0002863)2.87450550
24Small intestinal stenosis (HP:0012848)2.84743129
25Duodenal stenosis (HP:0100867)2.84743129
26Aplastic anemia (HP:0001915)2.81868934
27Multiple enchondromatosis (HP:0005701)2.79983413
28Degeneration of anterior horn cells (HP:0002398)2.78017737
29Abnormality of the anterior horn cell (HP:0006802)2.78017737
30Absent forearm bone (HP:0003953)2.76363444
31Aplasia involving forearm bones (HP:0009822)2.76363444
32Increased nuchal translucency (HP:0010880)2.74313626
33Carpal bone hypoplasia (HP:0001498)2.73621404
34Volvulus (HP:0002580)2.72689577
35Impulsivity (HP:0100710)2.71790863
36Proximal placement of thumb (HP:0009623)2.70327799
37Abnormality of cells of the erythroid lineage (HP:0012130)2.62589330
38Missing ribs (HP:0000921)2.58320358
39* Astrocytoma (HP:0009592)2.56695026
40* Abnormality of the astrocytes (HP:0100707)2.56695026
41Deviation of the thumb (HP:0009603)2.56225904
42* Colon cancer (HP:0003003)2.55686239
43Spastic diplegia (HP:0001264)2.55464071
44* Rhabdomyosarcoma (HP:0002859)2.51925829
45* Neoplasm of the oral cavity (HP:0100649)2.50282982
46Abnormality of the duodenum (HP:0002246)2.47292784
47Sloping forehead (HP:0000340)2.46198502
48Bone marrow hypocellularity (HP:0005528)2.43732843
49Abnormality of abdominal situs (HP:0011620)2.41667740
50Abdominal situs inversus (HP:0003363)2.41667740
51* Neoplasm of the pancreas (HP:0002894)2.41117377
52Abnormality of the carotid arteries (HP:0005344)2.39952431
5311 pairs of ribs (HP:0000878)2.38485466
54Abnormal lung lobation (HP:0002101)2.38154104
55Ectopic kidney (HP:0000086)2.37893471
56Tracheoesophageal fistula (HP:0002575)2.37697021
57Rough bone trabeculation (HP:0100670)2.36888710
58Rib fusion (HP:0000902)2.33768890
59Abnormal number of erythroid precursors (HP:0012131)2.31983090
60Asplenia (HP:0001746)2.31376171
61* Agnosia (HP:0010524)2.31347959
62Esophageal atresia (HP:0002032)2.30965845
63Microvesicular hepatic steatosis (HP:0001414)2.30550560
64Aplasia/hypoplasia of the humerus (HP:0006507)2.29347957
65* Glioma (HP:0009733)2.28279694
66Septo-optic dysplasia (HP:0100842)2.27819879
67Atresia of the external auditory canal (HP:0000413)2.27312780
68Premature graying of hair (HP:0002216)2.26346377
69Nephroblastoma (Wilms tumor) (HP:0002667)2.25397746
70Aplasia/Hypoplasia of the sternum (HP:0006714)2.24416831
71* Basal cell carcinoma (HP:0002671)2.23969922
72Cerebral hypomyelination (HP:0006808)2.23693704
73Hyperglycinemia (HP:0002154)2.22886166
74* Cafe-au-lait spot (HP:0000957)2.18915564
75Horseshoe kidney (HP:0000085)2.13607826
76Pancreatic islet-cell hyperplasia (HP:0004510)2.12919537
77Prominent nose (HP:0000448)2.11947619
78Aplasia/Hypoplasia of the spleen (HP:0010451)2.11868746
79* Neoplasm of striated muscle (HP:0009728)2.11718720
80Cellular immunodeficiency (HP:0005374)2.08584862
81Abnormality of cochlea (HP:0000375)2.07693876
82Embryonal neoplasm (HP:0002898)2.07507008
83High anterior hairline (HP:0009890)2.07428361
84Embryonal renal neoplasm (HP:0011794)2.06897100
85Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.05206801
86Short thumb (HP:0009778)2.04827866
87Triphalangeal thumb (HP:0001199)2.03762635
88Abnormality of serum amino acid levels (HP:0003112)2.03724242
89Aplasia/Hypoplasia of the sacrum (HP:0008517)2.02520573
90Short humerus (HP:0005792)2.02411603
91High pitched voice (HP:0001620)1.98783926
92Duplicated collecting system (HP:0000081)1.98436164
93Abnormality of the septum pellucidum (HP:0007375)1.97480129
94Neoplasm of the adrenal cortex (HP:0100641)1.94360570
95* Neoplasm of the colon (HP:0100273)1.93755063
96Trismus (HP:0000211)1.93717832
97Choanal atresia (HP:0000453)1.93656033
98Neoplasm of the adrenal gland (HP:0100631)1.93631047
99Stenosis of the external auditory canal (HP:0000402)1.93586151
100Bifid tongue (HP:0010297)1.93388128
101Supernumerary bones of the axial skeleton (HP:0009144)1.93278103
102* Ovarian neoplasm (HP:0100615)1.92051019
103Clubbing of toes (HP:0100760)1.91881502
104Pallor (HP:0000980)1.91678166
105* Biliary tract neoplasm (HP:0100574)1.91367439
106Abnormality of methionine metabolism (HP:0010901)1.91134141
107Squamous cell carcinoma (HP:0002860)1.90905735
108Microretrognathia (HP:0000308)1.90004005
109Shawl scrotum (HP:0000049)1.89608253
110Atrophy/Degeneration involving motor neurons (HP:0007373)1.89119422
111Premature ovarian failure (HP:0008209)1.88069818
112Facial cleft (HP:0002006)1.87917322
113Macrocytic anemia (HP:0001972)1.87854653
114Spinal muscular atrophy (HP:0007269)1.87137517
115Absent septum pellucidum (HP:0001331)1.87048385
116Gastrointestinal atresia (HP:0002589)1.86295652
117Facial hemangioma (HP:0000329)1.86179156
118Abnormality of glycolysis (HP:0004366)1.85178401
119Short 4th metacarpal (HP:0010044)1.84459893
120Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.84459893
121Abnormality of serine family amino acid metabolism (HP:0010894)1.83618686
122Abnormality of glycine metabolism (HP:0010895)1.83618686
123Increased serum pyruvate (HP:0003542)1.82431002
124Abnormality of DNA repair (HP:0003254)1.81850126
125Clitoromegaly (HP:0000057)1.79563045
126Abnormality of the clitoris (HP:0000056)1.79205995
127Progressive external ophthalmoplegia (HP:0000590)1.77522671
128Duplication of thumb phalanx (HP:0009942)1.75398892
129Postnatal microcephaly (HP:0005484)1.74946735
130Intestinal atresia (HP:0011100)1.73558401
131Bilateral microphthalmos (HP:0007633)1.73076176
132Hyperglycinuria (HP:0003108)1.72678923
133Gonadotropin excess (HP:0000837)1.72095850
134Acute encephalopathy (HP:0006846)1.70135351
135Arteriovenous malformation (HP:0100026)1.66566295
136Hepatoblastoma (HP:0002884)1.66175024
137Abnormality of aspartate family amino acid metabolism (HP:0010899)1.65418749
138Increased hepatocellular lipid droplets (HP:0006565)1.65234287
139Abnormal hair whorl (HP:0010721)1.64463978
140Shoulder girdle muscle weakness (HP:0003547)1.59112990
141Aqueductal stenosis (HP:0002410)1.59059642
142Aplasia/Hypoplasia of the breasts (HP:0010311)1.56379653
143Hypoplastic female external genitalia (HP:0012815)1.54694467
144Breast aplasia (HP:0100783)1.54666050
145Megaloblastic anemia (HP:0001889)1.54321855
146Hypoglycemic seizures (HP:0002173)1.53819436
147Acute necrotizing encephalopathy (HP:0006965)1.53737763
148Abnormality of homocysteine metabolism (HP:0010919)1.53276591

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.90783501
2WEE14.42248574
3BUB13.70694679
4CDK123.06552912
5NEK22.79341174
6PBK2.78571977
7TTK2.77903917
8NEK12.75756364
9TSSK62.74568067
10EEF2K2.65431959
11RPS6KB22.46521698
12VRK22.45652816
13PASK2.35452721
14SRPK12.31280098
15ACVR1B2.23709301
16PLK12.10071479
17CDK72.08673279
18TRIM282.06272348
19TAF12.02969650
20ATR2.00567184
21EPHA21.90024587
22EIF2AK11.86539217
23NUAK11.78604159
24MKNK11.72069832
25AURKB1.66361940
26BRSK21.64091725
27CHEK21.62775226
28TGFBR11.62238326
29BRD41.61659430
30PLK31.59646732
31CDK41.55914923
32MST41.54093884
33TNIK1.48523054
34MAP3K101.48190138
35DYRK31.48081700
36TLK11.47590201
37CHEK11.47450254
38TESK21.42798509
39PLK41.42788673
40VRK11.39167339
41WNK31.38225458
42SCYL21.34963060
43MAP3K81.34633095
44EIF2AK31.31811053
45FLT31.29430424
46STK101.27900530
47AURKA1.27467246
48PAK41.21762594
49MKNK21.19631568
50RPS6KA41.18112744
51MAPKAPK31.13423639
52ATM1.13154388
53STK41.12470096
54CDK21.07546714
55PKN21.06772375
56PNCK1.06746788
57BRSK11.05826843
58BCR1.03773039
59EIF2AK21.01000058
60NME11.00546335
61ALK1.00073257
62STK160.91195099
63LATS10.90127398
64PIM10.88754180
65NME20.88192047
66CSNK1G10.87765429
67SMG10.87740242
68CDK60.87679788
69BMPR1B0.82934504
70CCNB10.81162934
71CDK10.79751090
72DYRK20.77489461
73ERBB40.75274511
74CSNK2A20.74244350
75PRKCI0.72592975
76CSNK1G30.68226216
77ZAK0.66548644
78CDK80.65614221
79MELK0.64778442
80CSNK1G20.64592650
81MTOR0.64220725
82CSNK2A10.60297560
83AKT30.56626082
84PLK20.55578053
85CSNK1A1L0.53955386
86CSNK1E0.53066516
87MAP3K40.52540560
88PAK10.52212059
89MAP4K10.51619814
90PRKDC0.48768579
91DAPK10.47226325
92CSNK1D0.45609861
93AKT20.44433076
94LRRK20.43630862
95CDK30.42683628
96LATS20.42477565
97PDK20.40832902
98RPS6KA50.39771888
99GRK60.38940774
100CDK180.38793287
101MAPK140.38610672
102CDK190.37574058
103YES10.34856775
104ERBB30.34306199
105FGFR10.33933022
106CDK150.33741903
107STK30.32835667
108MINK10.32694518
109CDK11A0.32668839
110RPS6KB10.32263705
111MAP2K30.31434051
112CDK140.31067184
113CLK10.30385974
114AKT10.30138845
115GSK3B0.28781403
116STK38L0.28250056
117BRAF0.26353535
118OXSR10.26225029
119FGFR20.26210919
120CDK90.25434802
121MAPK10.25426367
122MAPK110.25083120
123MAP4K20.24711904
124TAOK20.23987836
125RPS6KA10.21576963
126MATK0.21488991
127CSF1R0.18536580
128PAK20.18034776
129BTK0.17171529
130PDK30.17068357
131PDK40.17068357
132RPS6KL10.16946026
133RPS6KC10.16946026

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.41961858
2* Mismatch repair_Homo sapiens_hsa034304.72597177
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.72422138
4Spliceosome_Homo sapiens_hsa030403.50183205
5RNA transport_Homo sapiens_hsa030133.32081925
6Homologous recombination_Homo sapiens_hsa034403.24384378
7Base excision repair_Homo sapiens_hsa034103.22449843
8Nucleotide excision repair_Homo sapiens_hsa034203.07103273
9Cell cycle_Homo sapiens_hsa041102.98987055
10One carbon pool by folate_Homo sapiens_hsa006702.98113204
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.90382257
12Ribosome_Homo sapiens_hsa030102.88373926
13RNA polymerase_Homo sapiens_hsa030202.62465782
14Fanconi anemia pathway_Homo sapiens_hsa034602.60514475
15Non-homologous end-joining_Homo sapiens_hsa034502.45205254
16Proteasome_Homo sapiens_hsa030502.40055001
17Pyrimidine metabolism_Homo sapiens_hsa002402.14713167
18mRNA surveillance pathway_Homo sapiens_hsa030152.06980866
19RNA degradation_Homo sapiens_hsa030182.01560650
20Basal transcription factors_Homo sapiens_hsa030221.78353409
21Protein export_Homo sapiens_hsa030601.69166056
22p53 signaling pathway_Homo sapiens_hsa041151.59699190
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.51959227
24Propanoate metabolism_Homo sapiens_hsa006401.45482491
25Pyruvate metabolism_Homo sapiens_hsa006201.43290257
26Vitamin B6 metabolism_Homo sapiens_hsa007501.42511770
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.39625262
28Steroid biosynthesis_Homo sapiens_hsa001001.37880919
29Systemic lupus erythematosus_Homo sapiens_hsa053221.32951817
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.23645105
31Oocyte meiosis_Homo sapiens_hsa041141.15162076
32Epstein-Barr virus infection_Homo sapiens_hsa051691.11553919
33Purine metabolism_Homo sapiens_hsa002301.11367584
34Viral carcinogenesis_Homo sapiens_hsa052031.08581628
35Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.03812848
36Fatty acid elongation_Homo sapiens_hsa000621.00509969
37Biosynthesis of amino acids_Homo sapiens_hsa012300.99468582
38Parkinsons disease_Homo sapiens_hsa050120.92898261
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.92032157
40Antigen processing and presentation_Homo sapiens_hsa046120.89820064
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.88176735
42Herpes simplex infection_Homo sapiens_hsa051680.86455743
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85519885
44Selenocompound metabolism_Homo sapiens_hsa004500.84082005
45HTLV-I infection_Homo sapiens_hsa051660.81459981
46MicroRNAs in cancer_Homo sapiens_hsa052060.80621344
47Thyroid cancer_Homo sapiens_hsa052160.79330259
48Cyanoamino acid metabolism_Homo sapiens_hsa004600.78507613
49Cysteine and methionine metabolism_Homo sapiens_hsa002700.77515330
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.76106852
51Oxidative phosphorylation_Homo sapiens_hsa001900.71408672
52Basal cell carcinoma_Homo sapiens_hsa052170.70299401
53Hippo signaling pathway_Homo sapiens_hsa043900.69018980
54Pentose phosphate pathway_Homo sapiens_hsa000300.66041888
55Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64083536
562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63717292
57Alcoholism_Homo sapiens_hsa050340.61483032
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60557399
59Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59628281
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.59114695
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.57098850
62Notch signaling pathway_Homo sapiens_hsa043300.57054448
63* Colorectal cancer_Homo sapiens_hsa052100.54648120
64Folate biosynthesis_Homo sapiens_hsa007900.53118486
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52727358
66Small cell lung cancer_Homo sapiens_hsa052220.52237417
67TGF-beta signaling pathway_Homo sapiens_hsa043500.51695295
68Carbon metabolism_Homo sapiens_hsa012000.48655023
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.47486295
70Metabolic pathways_Homo sapiens_hsa011000.46994984
71Hedgehog signaling pathway_Homo sapiens_hsa043400.44282939
72Fructose and mannose metabolism_Homo sapiens_hsa000510.43571941
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.42859340
74mTOR signaling pathway_Homo sapiens_hsa041500.42545518
75Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.41823455
76Primary immunodeficiency_Homo sapiens_hsa053400.41242495
77Fatty acid metabolism_Homo sapiens_hsa012120.40726183
78Legionellosis_Homo sapiens_hsa051340.40456766
79Adherens junction_Homo sapiens_hsa045200.38308643
80Arginine and proline metabolism_Homo sapiens_hsa003300.38260301
81Bladder cancer_Homo sapiens_hsa052190.37623420
82Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.36538366
83Chronic myeloid leukemia_Homo sapiens_hsa052200.36389675
84Lysine degradation_Homo sapiens_hsa003100.34806663
85Alzheimers disease_Homo sapiens_hsa050100.34557655
86* Pathways in cancer_Homo sapiens_hsa052000.34209988
87Apoptosis_Homo sapiens_hsa042100.33952016
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31657827
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.30787107
90HIF-1 signaling pathway_Homo sapiens_hsa040660.29470178
91Hepatitis B_Homo sapiens_hsa051610.28188522
92Wnt signaling pathway_Homo sapiens_hsa043100.28154027
93Vitamin digestion and absorption_Homo sapiens_hsa049770.28060869
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.26770626
95Sulfur relay system_Homo sapiens_hsa041220.26169257
96Galactose metabolism_Homo sapiens_hsa000520.25867002
97Non-small cell lung cancer_Homo sapiens_hsa052230.25280146
98Glutathione metabolism_Homo sapiens_hsa004800.24154576
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23897659
100Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.23466501
101Tight junction_Homo sapiens_hsa045300.23080201
102Shigellosis_Homo sapiens_hsa051310.22527146
103beta-Alanine metabolism_Homo sapiens_hsa004100.19994769
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19618683
105Butanoate metabolism_Homo sapiens_hsa006500.19189000
106Endometrial cancer_Homo sapiens_hsa052130.18742350
107Prostate cancer_Homo sapiens_hsa052150.18719389
108Acute myeloid leukemia_Homo sapiens_hsa052210.18718836
109N-Glycan biosynthesis_Homo sapiens_hsa005100.17872836
110Viral myocarditis_Homo sapiens_hsa054160.17433577
111Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17373185
112Renin-angiotensin system_Homo sapiens_hsa046140.15645642
113Fatty acid degradation_Homo sapiens_hsa000710.15086458
114Melanoma_Homo sapiens_hsa052180.14785218
115Measles_Homo sapiens_hsa051620.12630634
116Influenza A_Homo sapiens_hsa051640.10503365
117Arginine biosynthesis_Homo sapiens_hsa002200.09697490
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.09665155
119Peroxisome_Homo sapiens_hsa041460.09560499
120Pancreatic cancer_Homo sapiens_hsa052120.09547928
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.09435412
122PI3K-Akt signaling pathway_Homo sapiens_hsa041510.07440575
123FoxO signaling pathway_Homo sapiens_hsa040680.06619385
124Proteoglycans in cancer_Homo sapiens_hsa052050.05992736
125Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.04542083
126NF-kappa B signaling pathway_Homo sapiens_hsa040640.04067141
127Huntingtons disease_Homo sapiens_hsa050160.03993772
128Neurotrophin signaling pathway_Homo sapiens_hsa047220.02730775
129Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.02540448
130Taste transduction_Homo sapiens_hsa047420.02059545
131Nicotine addiction_Homo sapiens_hsa050330.01532148
132Phototransduction_Homo sapiens_hsa047440.01312364
133Tryptophan metabolism_Homo sapiens_hsa00380-0.0011854

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