MSANTD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.77349176
2protein localization to synapse (GO:0035418)5.11239753
3synaptic vesicle exocytosis (GO:0016079)5.08499166
4vocalization behavior (GO:0071625)5.07147346
5regulation of short-term neuronal synaptic plasticity (GO:0048172)5.00547211
6neuron cell-cell adhesion (GO:0007158)4.58199419
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.23138560
8positive regulation of synapse maturation (GO:0090129)4.19688330
9ionotropic glutamate receptor signaling pathway (GO:0035235)4.12144909
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.11506754
11regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.09636948
12glutamate receptor signaling pathway (GO:0007215)4.09171040
13response to histamine (GO:0034776)4.08102655
14neurotransmitter secretion (GO:0007269)3.99881106
15regulation of glutamate receptor signaling pathway (GO:1900449)3.99156294
16positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.98011483
17fucose catabolic process (GO:0019317)3.94388051
18L-fucose metabolic process (GO:0042354)3.94388051
19L-fucose catabolic process (GO:0042355)3.94388051
20innervation (GO:0060384)3.93130583
21DNA deamination (GO:0045006)3.90204188
22regulation of synaptic vesicle exocytosis (GO:2000300)3.85764630
23positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.82062528
24gamma-aminobutyric acid signaling pathway (GO:0007214)3.77826339
25neurotransmitter-gated ion channel clustering (GO:0072578)3.66655532
26regulation of long-term neuronal synaptic plasticity (GO:0048169)3.65707072
27proline transport (GO:0015824)3.65511558
28long-term synaptic potentiation (GO:0060291)3.63543190
29epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.62610725
30synaptic vesicle endocytosis (GO:0048488)3.57834352
31detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.55916684
32exploration behavior (GO:0035640)3.54932909
33synaptic transmission, glutamatergic (GO:0035249)3.53723148
34neuron-neuron synaptic transmission (GO:0007270)3.53273579
35locomotory exploration behavior (GO:0035641)3.52443969
36neuron recognition (GO:0008038)3.51455622
37prepulse inhibition (GO:0060134)3.51066542
38response to pheromone (GO:0019236)3.50813359
39piRNA metabolic process (GO:0034587)3.49942711
40regulation of synaptic vesicle transport (GO:1902803)3.49704007
41regulation of synapse structural plasticity (GO:0051823)3.46593500
42regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.46328989
43regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.46328989
44platelet dense granule organization (GO:0060155)3.45649157
45gamma-aminobutyric acid transport (GO:0015812)3.45430665
46regulation of vesicle fusion (GO:0031338)3.45393771
47detection of calcium ion (GO:0005513)3.43918186
48long-term memory (GO:0007616)3.43353050
49G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.43263542
50indolalkylamine metabolic process (GO:0006586)3.41874261
51striatum development (GO:0021756)3.40991357
52regulation of glutamate secretion (GO:0014048)3.40794439
53postsynaptic membrane organization (GO:0001941)3.40615055
54negative regulation of synaptic transmission, GABAergic (GO:0032229)3.39923693
55layer formation in cerebral cortex (GO:0021819)3.39123284
56glutamate secretion (GO:0014047)3.38036872
57regulation of synapse maturation (GO:0090128)3.37633645
58positive regulation of synaptic transmission, GABAergic (GO:0032230)3.37506449
59neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.37197751
60kynurenine metabolic process (GO:0070189)3.37173173
61positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.35869383
62tryptophan catabolic process (GO:0006569)3.35075853
63indole-containing compound catabolic process (GO:0042436)3.35075853
64indolalkylamine catabolic process (GO:0046218)3.35075853
65pyrimidine nucleobase catabolic process (GO:0006208)3.32747546
66cell migration in hindbrain (GO:0021535)3.32624117
67detection of light stimulus involved in sensory perception (GO:0050962)3.31872891
68detection of light stimulus involved in visual perception (GO:0050908)3.31872891
69positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.31861571
70positive regulation of action potential (GO:0045760)3.31032559
71neurotransmitter transport (GO:0006836)3.29361596
72regulation of excitatory postsynaptic membrane potential (GO:0060079)3.29191981
73neuronal action potential (GO:0019228)3.28602835
74regulation of neuronal synaptic plasticity (GO:0048168)3.28076206
75regulation of synaptic transmission, glutamatergic (GO:0051966)3.26781184
76cellular ketone body metabolic process (GO:0046950)3.24984946
77protein-cofactor linkage (GO:0018065)3.20554109
78learning (GO:0007612)3.16914474
79negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.14928725
80negative regulation of cell killing (GO:0031342)3.14928725
81behavioral response to cocaine (GO:0048148)3.14324297
82synaptic vesicle maturation (GO:0016188)3.11359136
83regulation of synaptic transmission, GABAergic (GO:0032228)3.11145933
84cerebellar Purkinje cell differentiation (GO:0021702)3.10910712
85positive regulation of CREB transcription factor activity (GO:0032793)3.09794026
86regulation of synaptic plasticity (GO:0048167)3.09734806
87somatic diversification of immune receptors via somatic mutation (GO:0002566)3.09523354
88somatic hypermutation of immunoglobulin genes (GO:0016446)3.09523354
89respiratory chain complex IV assembly (GO:0008535)3.09118661
90epithelial cilium movement (GO:0003351)3.08279328
91nucleobase catabolic process (GO:0046113)3.07971452
92vesicle transport along microtubule (GO:0047496)3.07304722
93behavioral fear response (GO:0001662)3.07116042
94behavioral defense response (GO:0002209)3.07116042
95nephron tubule morphogenesis (GO:0072078)3.06824135
96nephron epithelium morphogenesis (GO:0072088)3.06824135
97synapse assembly (GO:0007416)3.06814997
98regulation of action potential (GO:0098900)3.06749454
99regulation of postsynaptic membrane potential (GO:0060078)3.06013819
100regulation of cilium movement (GO:0003352)3.05678992
101dopamine receptor signaling pathway (GO:0007212)3.04217356
102axoneme assembly (GO:0035082)3.01342482
103ketone body metabolic process (GO:1902224)2.98496067
104DNA methylation involved in gamete generation (GO:0043046)2.97861792
105positive regulation of fibroblast migration (GO:0010763)2.96832803
106preassembly of GPI anchor in ER membrane (GO:0016254)2.96625835
107negative regulation of amino acid transport (GO:0051956)2.94577508
108fear response (GO:0042596)2.94457154
109activation of protein kinase A activity (GO:0034199)2.94299615
110membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.94074696
111L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.92912869
112regulation of glucokinase activity (GO:0033131)2.91795839
113regulation of hexokinase activity (GO:1903299)2.91795839
114transmission of nerve impulse (GO:0019226)2.90768461
115adaptation of signaling pathway (GO:0023058)2.90724527
116negative regulation of amine transport (GO:0051953)2.90594057
117water-soluble vitamin biosynthetic process (GO:0042364)2.90367325
118positive regulation of synaptic transmission (GO:0050806)2.89583555
119regulation of neurotransmitter levels (GO:0001505)2.89446222
120ATP hydrolysis coupled proton transport (GO:0015991)2.88270876
121energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.88270876
122adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.88175632
123glycerophospholipid catabolic process (GO:0046475)2.87475145
124positive regulation of membrane potential (GO:0045838)2.87192078
125tryptophan metabolic process (GO:0006568)2.86289155
126detection of temperature stimulus involved in sensory perception (GO:0050961)2.86132888
127detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.86132888
128associative learning (GO:0008306)2.85370920
129cilium or flagellum-dependent cell motility (GO:0001539)2.85333537
130regulation of neurotransmitter secretion (GO:0046928)2.85206982
131positive regulation of dendritic spine morphogenesis (GO:0061003)2.85004644
132startle response (GO:0001964)2.84704079
133positive regulation of neurotransmitter transport (GO:0051590)2.84692801
134cAMP catabolic process (GO:0006198)2.84328986
135synaptic transmission, cholinergic (GO:0007271)2.84230463
136synaptic transmission (GO:0007268)2.84151591
137negative regulation of telomere maintenance (GO:0032205)2.83202562
138clathrin coat assembly (GO:0048268)2.82818148
139suckling behavior (GO:0001967)2.82522209
140axonal fasciculation (GO:0007413)2.80903351
141kidney morphogenesis (GO:0060993)2.80811786
142response to amphetamine (GO:0001975)2.80613382
143regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.80523276
144regulation of dopamine secretion (GO:0014059)2.80283086
145catecholamine transport (GO:0051937)2.79954982
146regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.79578410
147negative regulation of homotypic cell-cell adhesion (GO:0034111)2.79446447
148membrane depolarization during action potential (GO:0086010)2.79362123
149amine catabolic process (GO:0009310)2.79250852
150cellular biogenic amine catabolic process (GO:0042402)2.79250852
151mannosylation (GO:0097502)2.75004277
152cytochrome complex assembly (GO:0017004)2.72974154
153protein polyglutamylation (GO:0018095)2.72833802
154indole-containing compound metabolic process (GO:0042430)2.72435851
155dopamine transport (GO:0015872)2.71900113
156protein complex biogenesis (GO:0070271)2.71191003
157nonmotile primary cilium assembly (GO:0035058)2.70023431
158amino acid salvage (GO:0043102)2.69301257
159L-methionine salvage (GO:0071267)2.69301257
160L-methionine biosynthetic process (GO:0071265)2.69301257
161cytidine catabolic process (GO:0006216)2.68314338
162cytidine deamination (GO:0009972)2.68314338
163cytidine metabolic process (GO:0046087)2.68314338
164reflex (GO:0060004)2.67607860
165cilium movement (GO:0003341)2.65675352
166sulfation (GO:0051923)2.64878111
167cellular response to ATP (GO:0071318)2.62638342
168mitochondrial respiratory chain complex I assembly (GO:0032981)2.58428305
169NADH dehydrogenase complex assembly (GO:0010257)2.58428305
170mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.58428305
171somite rostral/caudal axis specification (GO:0032525)2.57916077
172behavioral response to ethanol (GO:0048149)2.57588068
173primary amino compound metabolic process (GO:1901160)2.57381167
174negative regulation of mast cell activation (GO:0033004)2.56897307
175cyclic nucleotide catabolic process (GO:0009214)2.55920753
176neural tube formation (GO:0001841)2.55539581
177mitochondrial respiratory chain complex assembly (GO:0033108)2.52976623
178protein import into peroxisome matrix (GO:0016558)2.52879939
179renal tubule morphogenesis (GO:0061333)2.48472649
180cornea development in camera-type eye (GO:0061303)2.47918815
181sperm motility (GO:0030317)2.46679425
182reciprocal meiotic recombination (GO:0007131)2.43993551
183reciprocal DNA recombination (GO:0035825)2.43993551
184regulation of nuclear cell cycle DNA replication (GO:0033262)2.43847281
185negative regulation of cytosolic calcium ion concentration (GO:0051481)2.42928307
186rhodopsin mediated signaling pathway (GO:0016056)2.38629273
187photoreceptor cell maintenance (GO:0045494)2.38201377
188alanine transport (GO:0032328)2.38099844
189positive regulation of meiosis (GO:0045836)2.37915815
190pyrimidine ribonucleoside catabolic process (GO:0046133)2.37182032

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.17904218
2GBX2_23144817_ChIP-Seq_PC3_Human4.12678477
3VDR_22108803_ChIP-Seq_LS180_Human3.14746686
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.12035313
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.06550260
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.98783472
7IKZF1_21737484_ChIP-ChIP_HCT116_Human2.82208351
8REST_21632747_ChIP-Seq_MESCs_Mouse2.78081811
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.72909728
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56368081
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.53585462
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.47481021
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46310615
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.44526434
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.41254959
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.32549130
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.26739906
18RNF2_18974828_ChIP-Seq_MESCs_Mouse2.26739906
19AR_21572438_ChIP-Seq_LNCaP_Human2.23861821
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.23337089
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.22524917
22CTBP2_25329375_ChIP-Seq_LNCAP_Human2.19348772
23DROSHA_22980978_ChIP-Seq_HELA_Human2.16278910
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.13527436
25CTBP1_25329375_ChIP-Seq_LNCAP_Human2.13390322
26SUZ12_27294783_Chip-Seq_ESCs_Mouse2.08162140
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.05945420
28EED_16625203_ChIP-ChIP_MESCs_Mouse2.04983603
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.99992985
30FLI1_27457419_Chip-Seq_LIVER_Mouse1.96464226
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.96429641
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.87931898
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.86644956
34SMAD4_21799915_ChIP-Seq_A2780_Human1.86284918
35VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.85391470
36EWS_26573619_Chip-Seq_HEK293_Human1.82064279
37P300_19829295_ChIP-Seq_ESCs_Human1.81314338
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.80582187
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79602867
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73473973
41IRF1_19129219_ChIP-ChIP_H3396_Human1.66655267
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.64627082
43EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.64466311
44ZNF274_21170338_ChIP-Seq_K562_Hela1.64124065
45FUS_26573619_Chip-Seq_HEK293_Human1.63657761
46PCGF2_27294783_Chip-Seq_ESCs_Mouse1.63209557
47BMI1_23680149_ChIP-Seq_NPCS_Mouse1.58711309
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.54480398
49SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53820458
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52703828
51NR3C1_23031785_ChIP-Seq_PC12_Mouse1.50955745
52TP53_22573176_ChIP-Seq_HFKS_Human1.50580773
53TAF15_26573619_Chip-Seq_HEK293_Human1.49337792
54AR_25329375_ChIP-Seq_VCAP_Human1.49332423
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.48630624
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.46106336
57MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44668305
58GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.43635070
59IGF1R_20145208_ChIP-Seq_DFB_Human1.42558291
60NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.41665994
61PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.41169334
62POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39337339
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39337339
64CDX2_19796622_ChIP-Seq_MESCs_Mouse1.39145366
65ERG_21242973_ChIP-ChIP_JURKAT_Human1.38855625
66SOX2_21211035_ChIP-Seq_LN229_Gbm1.36480551
67NCOR_22424771_ChIP-Seq_293T_Human1.35179921
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33642442
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.33582936
70GATA3_21878914_ChIP-Seq_MCF-7_Human1.32214982
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.31610582
72FOXA1_27270436_Chip-Seq_PROSTATE_Human1.30843814
73FOXA1_25329375_ChIP-Seq_VCAP_Human1.30843814
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.30488076
75EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.30279793
76E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.29132329
77P53_22127205_ChIP-Seq_FIBROBLAST_Human1.28416778
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28319738
79NANOG_19829295_ChIP-Seq_ESCs_Human1.28039840
80SOX2_19829295_ChIP-Seq_ESCs_Human1.28039840
81SMAD_19615063_ChIP-ChIP_OVARY_Human1.27761359
82FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.26584544
83ETV2_25802403_ChIP-Seq_MESCs_Mouse1.24389473
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.24268132
85PRDM14_20953172_ChIP-Seq_ESCs_Human1.24108301
86STAT3_23295773_ChIP-Seq_U87_Human1.22911485
87GABP_17652178_ChIP-ChIP_JURKAT_Human1.21361883
88CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21016009
89SUZ12_27294783_Chip-Seq_NPCs_Mouse1.18986502
90DNAJC2_21179169_ChIP-ChIP_NT2_Human1.18937021
91BCAT_22108803_ChIP-Seq_LS180_Human1.15975187
92OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14491653
93RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14095351
94SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13115862
95SMAD4_21741376_ChIP-Seq_EPCs_Human1.13074689
96NFE2_27457419_Chip-Seq_LIVER_Mouse1.12873322
97MYC_18940864_ChIP-ChIP_HL60_Human1.12647564
98JUN_21703547_ChIP-Seq_K562_Human1.12123890
99SMAD3_21741376_ChIP-Seq_ESCs_Human1.11931941
100TCF4_23295773_ChIP-Seq_U87_Human1.11699058
101RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11530240
102KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09998175
103FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09809358
104UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09269182
105YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08604494
106HOXB7_26014856_ChIP-Seq_BT474_Human1.07916714
107EZH2_27294783_Chip-Seq_NPCs_Mouse1.07644905
108AR_19668381_ChIP-Seq_PC3_Human1.07574391
109NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06681529
110CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.06603951
111RNF2_27304074_Chip-Seq_NSC_Mouse1.06330072
112NANOG_18555785_Chip-Seq_ESCs_Mouse1.05515159
113AR_20517297_ChIP-Seq_VCAP_Human1.05466469
114ERA_21632823_ChIP-Seq_H3396_Human1.04009643
115RUNX2_22187159_ChIP-Seq_PCA_Human1.03737132
116CBP_20019798_ChIP-Seq_JUKART_Human1.02856677
117IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.02856677
118MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.02218924
119CBX2_27304074_Chip-Seq_ESCs_Mouse1.01804333
120TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01610280
121AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01196140
122ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00294320
123EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99022567
124P53_22387025_ChIP-Seq_ESCs_Mouse0.98631166
125HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.98156729
126PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97650539
127TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97167468
128RING1B_27294783_Chip-Seq_ESCs_Mouse0.96829337
129MYC_19829295_ChIP-Seq_ESCs_Human0.95914979
130ELK4_26923725_Chip-Seq_MESODERM_Mouse0.95847800
131KDM2B_26808549_Chip-Seq_REH_Human0.95677566
132ER_23166858_ChIP-Seq_MCF-7_Human0.95435744
133MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94807622
134WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92022485
135TP53_18474530_ChIP-ChIP_U2OS_Human0.91271853
136RING1B_27294783_Chip-Seq_NPCs_Mouse0.90217427
137ARNT_22903824_ChIP-Seq_MCF-7_Human0.90206836
138FLI1_21867929_ChIP-Seq_TH2_Mouse0.88806686
139CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86986080
140TCF4_22108803_ChIP-Seq_LS180_Human0.82889587
141EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.81837305
142RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.81746434
143MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.80991579
144AHR_22903824_ChIP-Seq_MCF-7_Human0.79876232
145GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79140886
146GATA1_22025678_ChIP-Seq_K562_Human0.78350865

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy5.29478084
2MP0004859_abnormal_synaptic_plasticity5.18397831
3MP0003635_abnormal_synaptic_transmissio3.76151940
4MP0009745_abnormal_behavioral_response3.50449343
5MP0001968_abnormal_touch/_nociception3.35915927
6MP0004270_analgesia3.16960118
7MP0008877_abnormal_DNA_methylation3.16514645
8MP0002063_abnormal_learning/memory/cond3.15067435
9MP0002064_seizures3.04643919
10MP0002735_abnormal_chemical_nociception2.96848857
11MP0002572_abnormal_emotion/affect_behav2.86226023
12MP0002736_abnormal_nociception_after2.86041662
13MP0003195_calcinosis2.66598801
14MP0003880_abnormal_central_pattern2.54143391
15MP0002102_abnormal_ear_morphology2.46019604
16MP0009046_muscle_twitch2.44229880
17MP0006276_abnormal_autonomic_nervous2.40987618
18MP0002734_abnormal_mechanical_nocicepti2.36138954
19MP0004147_increased_porphyrin_level2.25128353
20MP0002272_abnormal_nervous_system2.24440293
21MP0002733_abnormal_thermal_nociception2.22635035
22MP0003787_abnormal_imprinting2.20875136
23MP0001970_abnormal_pain_threshold2.09117402
24MP0001440_abnormal_grooming_behavior2.09034885
25MP0001486_abnormal_startle_reflex2.02881733
26MP0002876_abnormal_thyroid_physiology2.02652702
27MP0002184_abnormal_innervation2.01778264
28MP0005423_abnormal_somatic_nervous2.00793762
29MP0008875_abnormal_xenobiotic_pharmacok1.90354219
30MP0002067_abnormal_sensory_capabilities1.89160917
31MP0001984_abnormal_olfaction1.86782361
32MP0005409_darkened_coat_color1.84112929
33MP0004043_abnormal_pH_regulation1.79983164
34MP0001529_abnormal_vocalization1.79689548
35MP0003122_maternal_imprinting1.78743299
36MP0001986_abnormal_taste_sensitivity1.78281637
37MP0010386_abnormal_urinary_bladder1.76313699
38MP0001188_hyperpigmentation1.74015542
39MP0002653_abnormal_ependyma_morphology1.73215834
40MP0004858_abnormal_nervous_system1.72532306
41MP0003283_abnormal_digestive_organ1.71866853
42MP0003183_abnormal_peptide_metabolism1.70072556
43MP0002837_dystrophic_cardiac_calcinosis1.67522535
44MP0005386_behavior/neurological_phenoty1.67244187
45MP0004924_abnormal_behavior1.67244187
46MP0003136_yellow_coat_color1.65630369
47MP0002557_abnormal_social/conspecific_i1.64438491
48MP0004811_abnormal_neuron_physiology1.64403263
49MP0001905_abnormal_dopamine_level1.63021889
50MP0001501_abnormal_sleep_pattern1.59839913
51MP0008569_lethality_at_weaning1.57725246
52MP0000569_abnormal_digit_pigmentation1.57087859
53MP0003011_delayed_dark_adaptation1.56602245
54MP0000427_abnormal_hair_cycle1.55091519
55MP0004133_heterotaxia1.53821508
56MP0003329_amyloid_beta_deposits1.52635268
57MP0005253_abnormal_eye_physiology1.51365273
58MP0003172_abnormal_lysosome_physiology1.50578039
59MP0000372_irregular_coat_pigmentation1.49832547
60MP0002909_abnormal_adrenal_gland1.45836068
61MP0001502_abnormal_circadian_rhythm1.41332627
62MP0008961_abnormal_basal_metabolism1.40847099
63MP0000778_abnormal_nervous_system1.40649864
64MP0003646_muscle_fatigue1.38242201
65MP0005551_abnormal_eye_electrophysiolog1.37533121
66MP0001485_abnormal_pinna_reflex1.34737957
67MP0005646_abnormal_pituitary_gland1.26826559
68MP0003879_abnormal_hair_cell1.26600180
69MP0000013_abnormal_adipose_tissue1.25501738
70MP0002882_abnormal_neuron_morphology1.25159847
71MP0005084_abnormal_gallbladder_morpholo1.23113836
72MP0002638_abnormal_pupillary_reflex1.21287827
73MP0002090_abnormal_vision1.20212393
74MP0002066_abnormal_motor_capabilities/c1.17756156
75MP0000955_abnormal_spinal_cord1.16436006
76MP0000751_myopathy1.13911889
77MP0002938_white_spotting1.12747406
78MP0003633_abnormal_nervous_system1.12366576
79MP0004142_abnormal_muscle_tone1.12222550
80MP0003121_genomic_imprinting1.11805535
81MP0000015_abnormal_ear_pigmentation1.11285144
82MP0005645_abnormal_hypothalamus_physiol1.09700723
83MP0003878_abnormal_ear_physiology1.08891625
84MP0005377_hearing/vestibular/ear_phenot1.08891625
85MP0004885_abnormal_endolymph1.01369639
86MP0002751_abnormal_autonomic_nervous1.00930177
87MP0002928_abnormal_bile_duct1.00248913
88MP0003631_nervous_system_phenotype0.99493622
89MP0004145_abnormal_muscle_electrophysio0.99207117
90MP0002069_abnormal_eating/drinking_beha0.99188241
91MP0005389_reproductive_system_phenotype0.98561325
92MP0009780_abnormal_chondrocyte_physiolo0.97556468
93MP0008995_early_reproductive_senescence0.97247781
94MP0005174_abnormal_tail_pigmentation0.97148033
95MP0002138_abnormal_hepatobiliary_system0.96464635
96MP0002277_abnormal_respiratory_mucosa0.96282638
97MP0004510_myositis0.96060206
98MP0001919_abnormal_reproductive_system0.95917554
99MP0010329_abnormal_lipoprotein_level0.94073883
100MP0002229_neurodegeneration0.93998410
101MP0003866_abnormal_defecation0.93789380
102MP0010234_abnormal_vibrissa_follicle0.93172248
103MP0002693_abnormal_pancreas_physiology0.92018780
104MP0005195_abnormal_posterior_eye0.91545691
105MP0005410_abnormal_fertilization0.90783899
106MP0005671_abnormal_response_to0.90615280
107MP0002152_abnormal_brain_morphology0.90098474
108MP0000026_abnormal_inner_ear0.88229983
109MP0008874_decreased_physiological_sensi0.87312812
110MP0000604_amyloidosis0.85355309
111MP0005332_abnormal_amino_acid0.84382723
112MP0003890_abnormal_embryonic-extraembry0.83762572
113MP0002160_abnormal_reproductive_system0.83426940
114MP0005310_abnormal_salivary_gland0.83419620
115MP0006292_abnormal_olfactory_placode0.82992417
116MP0005535_abnormal_body_temperature0.81667154
117MP0005379_endocrine/exocrine_gland_phen0.81664109
118MP0003252_abnormal_bile_duct0.80757319
119MP0003123_paternal_imprinting0.80588052
120MP0003698_abnormal_male_reproductive0.80016799
121MP0003634_abnormal_glial_cell0.78283761
122MP0001944_abnormal_pancreas_morphology0.75282022
123MP0005187_abnormal_penis_morphology0.74241637
124MP0008789_abnormal_olfactory_epithelium0.73438121
125MP0009764_decreased_sensitivity_to0.72133194
126MP0004085_abnormal_heartbeat0.70666659
127MP0004742_abnormal_vestibular_system0.68417067
128MP0006072_abnormal_retinal_apoptosis0.66420246
129MP0002009_preneoplasia0.66195501
130MP0003632_abnormal_nervous_system0.63588104
131MP0002752_abnormal_somatic_nervous0.63035891
132MP0005448_abnormal_energy_balance0.60331360
133MP0009697_abnormal_copulation0.59825892
134MP0002877_abnormal_melanocyte_morpholog0.59669614
135MP0004215_abnormal_myocardial_fiber0.59577669
136MP0000631_abnormal_neuroendocrine_gland0.57814727
137MP0001963_abnormal_hearing_physiology0.56998071
138MP0002078_abnormal_glucose_homeostasis0.55921301
139MP0008872_abnormal_physiological_respon0.55907992
140MP0004233_abnormal_muscle_weight0.54590772
141MP0002163_abnormal_gland_morphology0.53006670
142MP0003953_abnormal_hormone_level0.52027673
143MP0000230_abnormal_systemic_arterial0.48915150

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.87042116
2Visual hallucinations (HP:0002367)4.93986300
3Focal seizures (HP:0007359)4.85348824
4Myokymia (HP:0002411)4.83423182
5Atonic seizures (HP:0010819)4.80163263
6Febrile seizures (HP:0002373)4.73487120
7Pancreatic cysts (HP:0001737)4.20566205
8Absence seizures (HP:0002121)4.13464300
9Epileptic encephalopathy (HP:0200134)3.95405754
10Pancreatic fibrosis (HP:0100732)3.91854257
11Progressive cerebellar ataxia (HP:0002073)3.89110325
12Dialeptic seizures (HP:0011146)3.88855600
13Hyperventilation (HP:0002883)3.85151271
14True hermaphroditism (HP:0010459)3.76107998
15Abnormality of midbrain morphology (HP:0002418)3.66163516
16Molar tooth sign on MRI (HP:0002419)3.66163516
17Epileptiform EEG discharges (HP:0011182)3.49728572
18Mutism (HP:0002300)3.49465032
19Generalized tonic-clonic seizures (HP:0002069)3.37574681
20Type II lissencephaly (HP:0007260)3.36690428
21EEG with generalized epileptiform discharges (HP:0011198)3.34472540
22Nephronophthisis (HP:0000090)3.33425957
23Abnormality of the renal cortex (HP:0011035)3.33296870
24Abnormal hair whorl (HP:0010721)3.29540691
25Abnormal rod and cone electroretinograms (HP:0008323)3.26007591
26Hypsarrhythmia (HP:0002521)3.15135382
27Depression (HP:0000716)3.08462203
28Abnormality of binocular vision (HP:0011514)3.03679528
29Diplopia (HP:0000651)3.03679528
30Drooling (HP:0002307)2.96587925
31Excessive salivation (HP:0003781)2.96587925
32Anxiety (HP:0000739)2.95454931
33Attenuation of retinal blood vessels (HP:0007843)2.94878387
34Abnormality of the renal medulla (HP:0100957)2.91990508
35Broad-based gait (HP:0002136)2.83382854
36Pheochromocytoma (HP:0002666)2.82061105
37Action tremor (HP:0002345)2.78203992
38Pendular nystagmus (HP:0012043)2.71086889
39Truncal ataxia (HP:0002078)2.67008237
40Chronic hepatic failure (HP:0100626)2.66154266
41Renal cortical cysts (HP:0000803)2.65997474
42Status epilepticus (HP:0002133)2.64464661
43Congenital stationary night blindness (HP:0007642)2.62456044
44Abnormality of alanine metabolism (HP:0010916)2.62341248
45Hyperalaninemia (HP:0003348)2.62341248
46Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.62341248
47Abnormal social behavior (HP:0012433)2.61876965
48Impaired social interactions (HP:0000735)2.61876965
49Genetic anticipation (HP:0003743)2.59929525
50Protruding tongue (HP:0010808)2.56303118
51Progressive inability to walk (HP:0002505)2.54895647
52Polyphagia (HP:0002591)2.54200415
53Lissencephaly (HP:0001339)2.54054025
54Supranuclear gaze palsy (HP:0000605)2.49375992
55Hypoventilation (HP:0002791)2.46631637
56Neuroendocrine neoplasm (HP:0100634)2.45511211
57Dysmetric saccades (HP:0000641)2.45171322
58Exercise-induced myalgia (HP:0003738)2.44921071
59Hemiparesis (HP:0001269)2.44340594
60Tubular atrophy (HP:0000092)2.44315632
61Blue irides (HP:0000635)2.43645299
62Absent rod-and cone-mediated responses on ERG (HP:0007688)2.43489084
63Cystic liver disease (HP:0006706)2.43130681
64Polydipsia (HP:0001959)2.43039739
65Abnormal drinking behavior (HP:0030082)2.43039739
66Generalized myoclonic seizures (HP:0002123)2.42046067
67Gait imbalance (HP:0002141)2.39832568
68Decreased central vision (HP:0007663)2.39468165
69Dynein arm defect of respiratory motile cilia (HP:0012255)2.39148759
70Absent/shortened dynein arms (HP:0200106)2.39148759
71Dysmetria (HP:0001310)2.36389872
72Severe visual impairment (HP:0001141)2.35454225
73Cerebellar dysplasia (HP:0007033)2.34891823
74Sclerocornea (HP:0000647)2.31784125
75Dysdiadochokinesis (HP:0002075)2.31430157
76Abnormal respiratory epithelium morphology (HP:0012253)2.31393512
77Abnormal respiratory motile cilium morphology (HP:0005938)2.31393512
78Failure to thrive in infancy (HP:0001531)2.31027329
79Urinary bladder sphincter dysfunction (HP:0002839)2.30775115
80Pachygyria (HP:0001302)2.30195682
81Bradykinesia (HP:0002067)2.29138144
82Aplasia/Hypoplasia of the fovea (HP:0008060)2.28673439
83Hypoplasia of the fovea (HP:0007750)2.28673439
84Large for gestational age (HP:0001520)2.27623609
85Thickened helices (HP:0000391)2.27398336
86Poor suck (HP:0002033)2.23988727
87Keratoconus (HP:0000563)2.23674795
88Increased corneal curvature (HP:0100692)2.23674795
89Cerebral inclusion bodies (HP:0100314)2.23360280
90Abnormal eating behavior (HP:0100738)2.23065611
91Sensory axonal neuropathy (HP:0003390)2.20474394
92Postural instability (HP:0002172)2.20469162
93Psychosis (HP:0000709)2.20333792
94Poor eye contact (HP:0000817)2.18332102
95Abolished electroretinogram (ERG) (HP:0000550)2.18179701
96Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.15451353
97Aplasia/Hypoplasia of the tibia (HP:0005772)2.15397022
98Resting tremor (HP:0002322)2.13098069
99Delusions (HP:0000746)2.12986484
100Open mouth (HP:0000194)2.12082615
101Mitochondrial inheritance (HP:0001427)2.11592689
102Hypothermia (HP:0002045)2.10781889
103Concave nail (HP:0001598)2.10418303
104Exotropia (HP:0000577)2.09479110
105Agitation (HP:0000713)2.08712905
106Neuronal loss in central nervous system (HP:0002529)2.07612315
107Abnormal ciliary motility (HP:0012262)2.06787102
108Abnormality of salivation (HP:0100755)2.06589214
109Abnormality of the fovea (HP:0000493)2.05438040
110Lipid accumulation in hepatocytes (HP:0006561)2.05223730
111Generalized hypopigmentation (HP:0007513)2.04620780
112Gaze-evoked nystagmus (HP:0000640)2.04528798
113Decreased circulating renin level (HP:0003351)2.03270295
114Absent speech (HP:0001344)2.02767369
115Aplasia/Hypoplasia of the tongue (HP:0010295)2.00339246
116Orthostatic hypotension (HP:0001278)1.99673308
117Abnormal biliary tract physiology (HP:0012439)1.98356067
118Bile duct proliferation (HP:0001408)1.98356067
119Congenital primary aphakia (HP:0007707)1.97240121
120Optic disc pallor (HP:0000543)1.96793327
121Polyuria (HP:0000103)1.95974978
122Central scotoma (HP:0000603)1.95883332
123Furrowed tongue (HP:0000221)1.95716798
124Inappropriate behavior (HP:0000719)1.94855446
125Postural tremor (HP:0002174)1.94149132
126Anencephaly (HP:0002323)1.94120261
127Methylmalonic acidemia (HP:0002912)1.94021436
128Abnormality of macular pigmentation (HP:0008002)1.93430407
129Hyperthyroidism (HP:0000836)1.91416215
130Acute necrotizing encephalopathy (HP:0006965)1.91196516
131Increased CSF lactate (HP:0002490)1.90720920
132Inability to walk (HP:0002540)1.90667290
133Progressive macrocephaly (HP:0004481)1.90309351
134Male pseudohermaphroditism (HP:0000037)1.89993178
135Severe muscular hypotonia (HP:0006829)1.89861522
136Rapidly progressive (HP:0003678)1.89833343
137Ankle clonus (HP:0011448)1.89765034
138Progressive sensorineural hearing impairment (HP:0000408)1.89351013
139Impaired smooth pursuit (HP:0007772)1.88863407
140Widely spaced teeth (HP:0000687)1.88830987
141Bony spicule pigmentary retinopathy (HP:0007737)1.88337409
142Stomach cancer (HP:0012126)1.87791003
143Optic nerve hypoplasia (HP:0000609)1.87644107
144Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.86052876
145Amblyopia (HP:0000646)1.86000195
146Congenital, generalized hypertrichosis (HP:0004540)1.85756815
147Specific learning disability (HP:0001328)1.85216368
148Acute encephalopathy (HP:0006846)1.85073524
149Akinesia (HP:0002304)1.84362468
150Stereotypic behavior (HP:0000733)1.84012191
151Ketosis (HP:0001946)1.83237915
152Dementia (HP:0000726)1.82848968
153Patellar aplasia (HP:0006443)1.81896902
154Intestinal atresia (HP:0011100)1.81485946
155Aplasia/hypoplasia of the uterus (HP:0008684)1.80441876
156Abnormal mitochondria in muscle tissue (HP:0008316)1.79961226
157Decreased electroretinogram (ERG) amplitude (HP:0000654)1.79069950
158Focal dystonia (HP:0004373)1.79030511
159Medial flaring of the eyebrow (HP:0010747)1.78950506
1603-Methylglutaconic aciduria (HP:0003535)1.78863143
161Limb dystonia (HP:0002451)1.78666682
162Congenital hepatic fibrosis (HP:0002612)1.78622267
163Impaired vibratory sensation (HP:0002495)1.78285335
164Hypoplasia of the pons (HP:0012110)1.78226893
165Abnormality of the pons (HP:0007361)1.78223088
166Dysautonomia (HP:0002459)1.76944053
167Macroorchidism (HP:0000053)1.76647929
168Short tibia (HP:0005736)1.76558479
169Torticollis (HP:0000473)1.76374129
170Abnormal respiratory motile cilium physiology (HP:0012261)1.75599684
171Supernumerary spleens (HP:0009799)1.75450654
172Lower limb amyotrophy (HP:0007210)1.75356483
173Hepatic necrosis (HP:0002605)1.75159962
174Intellectual disability, progressive (HP:0006887)1.73385813
175Nephrogenic diabetes insipidus (HP:0009806)1.73330326
176Aplasia/Hypoplasia of the spleen (HP:0010451)1.73180774
177Impaired vibration sensation in the lower limbs (HP:0002166)1.72903259

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.65488312
2NTRK33.71581623
3MAP3K93.59042406
4MAP3K133.24999412
5RIPK43.12205732
6MAP4K22.96883985
7PINK12.96129904
8MAP3K122.85618963
9MAP3K42.84340833
10ZAK2.57043259
11GRK12.42521589
12MAP2K72.40674476
13BMPR1B2.37593229
14SIK22.36885166
15CASK2.34002736
16WNK42.32934522
17MARK12.30496813
18TLK12.29560658
19MINK12.21830907
20EPHA42.15702713
21NUAK12.14596122
22ACVR1B2.10558449
23INSRR2.09513191
24FES1.93051220
25ARAF1.85088283
26KSR21.79093419
27NTRK21.74555173
28MAPK131.71669209
29PRPF4B1.69691105
30PLK21.65208139
31PRKCH1.58311928
32MAP2K41.57857682
33EPHA31.51866353
34DYRK21.51814641
35TNIK1.50547710
36KSR11.42455468
37OXSR11.38094050
38DAPK11.37607457
39CDK51.35100520
40SGK21.35018594
41TXK1.34862759
42PAK31.33447635
43NTRK11.29737089
44GRK51.20904898
45SGK31.11643167
46MAPKAPK31.03794717
47SGK2231.03019376
48SGK4941.03019376
49PRKD21.02530311
50GRK71.02118400
51DAPK21.00917287
52STK38L1.00483925
53NME11.00084369
54CAMKK10.97579361
55PRKCG0.97518494
56PRKD30.97381700
57GRK60.97376991
58SYK0.96587199
59SIK30.95476752
60PNCK0.94709014
61MARK20.94386591
62STK390.93990772
63PIK3CA0.93593941
64PHKG10.90766563
65PHKG20.90766563
66TAOK30.89468461
67BCR0.88903674
68UHMK10.88478063
69MAP2K60.87193914
70CSNK1G10.86654051
71CSNK1G20.86600480
72PIK3CG0.86521725
73PRKCE0.86113283
74BCKDK0.85574176
75CAMK2A0.84950326
76PTK2B0.84642355
77CSNK1G30.83872971
78TRIM280.83866078
79ALK0.83756249
80WNK30.83713508
81HIPK20.76197432
82RAF10.75849073
83TGFBR10.74547710
84MATK0.72660772
85PDK10.72423071
86CAMKK20.72101155
87MAP3K20.70974471
88CAMK2B0.69912129
89SGK10.69640696
90FYN0.66446727
91PDPK10.66313065
92ERBB30.66131604
93VRK10.65077941
94PAK60.64956896
95IKBKB0.64396339
96MAPK150.64155066
97ADRBK20.64137572
98BMPR20.63849086
99CSNK1A1L0.63775077
100HCK0.63603839
101PKN10.62876058
102DYRK1A0.62316210
103RET0.61989132
104TIE10.61007151
105MAP3K70.59540017
106PRKCI0.59346909
107MKNK20.59162759
108SCYL20.57633561
109LMTK20.56737964
110CDK190.56001447
111CSNK1A10.55479774
112MAP3K10.55346180
113PRKACA0.55209378
114RPS6KB10.54698628
115MAPKAPK50.54638022
116FER0.53032548
117MOS0.52860865
118TSSK60.50810625
119CSNK1D0.50505770
120CDK180.50219131
121IRAK10.49941439
122ADRBK10.49514048
123CDK140.49376825
124CAMK2D0.49144038
125FGR0.49016116
126CDK150.48216564
127MAP2K10.46159821
128TNK20.45547325
129PRKCZ0.45334382
130PRKG10.45229785
131RPS6KA30.44497224
132KIT0.44271208
133PRKCB0.44129862
134PRKCQ0.44046492
135TEC0.43880524
136FGFR20.43543520
137STK110.41875276
138VRK20.41414331
139OBSCN0.41148129
140PRKCA0.40833980
141CAMK10.40536388
142CDK11A0.39967697
143BRSK20.39718443
144PRKAA20.38790493
145PRKAA10.38630817
146NLK0.38567654
147ROCK20.38293592
148STK30.37936654
149RPS6KA20.37093871
150MAP3K60.37081797
151CAMK40.36899305
152MST40.36655383
153CAMK1G0.36416438
154MAP4K10.35945468
155RPS6KA50.35305428
156CHUK0.34969467
157ITK0.30698140
158MUSK0.28282124

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.70492421
2Synaptic vesicle cycle_Homo sapiens_hsa047213.09336905
3GABAergic synapse_Homo sapiens_hsa047272.74196729
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.72493595
5Long-term potentiation_Homo sapiens_hsa047202.65780732
6Linoleic acid metabolism_Homo sapiens_hsa005912.54980167
7Circadian entrainment_Homo sapiens_hsa047132.54125614
8Maturity onset diabetes of the young_Homo sapiens_hsa049502.51614961
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.46433928
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.37165489
11Morphine addiction_Homo sapiens_hsa050322.36506621
12Amphetamine addiction_Homo sapiens_hsa050312.26067611
13Glutamatergic synapse_Homo sapiens_hsa047242.25718274
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.25390299
15Dopaminergic synapse_Homo sapiens_hsa047282.22848833
16Collecting duct acid secretion_Homo sapiens_hsa049662.19926054
17Insulin secretion_Homo sapiens_hsa049112.17178530
18Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.16690235
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.02858758
20Renin secretion_Homo sapiens_hsa049241.99715035
21Selenocompound metabolism_Homo sapiens_hsa004501.98646383
22Olfactory transduction_Homo sapiens_hsa047401.93252742
23Long-term depression_Homo sapiens_hsa047301.92187113
24Cholinergic synapse_Homo sapiens_hsa047251.87681372
25Serotonergic synapse_Homo sapiens_hsa047261.87455990
26Nitrogen metabolism_Homo sapiens_hsa009101.86588766
27Protein export_Homo sapiens_hsa030601.85513780
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.83528626
29Salivary secretion_Homo sapiens_hsa049701.80197304
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.73657624
31Ether lipid metabolism_Homo sapiens_hsa005651.68832604
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66416022
33Cocaine addiction_Homo sapiens_hsa050301.65173732
34Caffeine metabolism_Homo sapiens_hsa002321.61405021
35Tryptophan metabolism_Homo sapiens_hsa003801.60204097
36Oxytocin signaling pathway_Homo sapiens_hsa049211.58304500
37Gastric acid secretion_Homo sapiens_hsa049711.54415432
38Intestinal immune network for IgA production_Homo sapiens_hsa046721.51504181
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.50383119
40Vibrio cholerae infection_Homo sapiens_hsa051101.48680315
41Calcium signaling pathway_Homo sapiens_hsa040201.47858226
42Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.47304948
43Taste transduction_Homo sapiens_hsa047421.43689702
44Oxidative phosphorylation_Homo sapiens_hsa001901.41236530
45Alzheimers disease_Homo sapiens_hsa050101.40989545
46RNA polymerase_Homo sapiens_hsa030201.23128986
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.21415217
48Basal transcription factors_Homo sapiens_hsa030221.21150306
49Type II diabetes mellitus_Homo sapiens_hsa049301.20539246
50cAMP signaling pathway_Homo sapiens_hsa040241.20040881
51Estrogen signaling pathway_Homo sapiens_hsa049151.19518334
52GnRH signaling pathway_Homo sapiens_hsa049121.19303005
53Fanconi anemia pathway_Homo sapiens_hsa034601.18017735
54Peroxisome_Homo sapiens_hsa041461.17981684
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.15495830
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.14758253
57Phototransduction_Homo sapiens_hsa047441.14621932
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.11957424
59Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.11949731
60Propanoate metabolism_Homo sapiens_hsa006401.11667595
61Chemical carcinogenesis_Homo sapiens_hsa052041.11277134
62Gap junction_Homo sapiens_hsa045401.09085739
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.08621304
64Cardiac muscle contraction_Homo sapiens_hsa042601.08582953
65Homologous recombination_Homo sapiens_hsa034401.08353820
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.06853083
67Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04814507
68Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.04167378
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.03939226
70cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03314758
71Arachidonic acid metabolism_Homo sapiens_hsa005901.02636339
72Steroid hormone biosynthesis_Homo sapiens_hsa001401.00295152
73Asthma_Homo sapiens_hsa053100.98045005
74Primary immunodeficiency_Homo sapiens_hsa053400.97451066
75Glucagon signaling pathway_Homo sapiens_hsa049220.97072864
76Type I diabetes mellitus_Homo sapiens_hsa049400.96281597
77Parkinsons disease_Homo sapiens_hsa050120.96044884
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.93946476
79ABC transporters_Homo sapiens_hsa020100.93074092
80Glioma_Homo sapiens_hsa052140.92095683
81Regulation of autophagy_Homo sapiens_hsa041400.91986847
82Retinol metabolism_Homo sapiens_hsa008300.90937501
83Fat digestion and absorption_Homo sapiens_hsa049750.86810626
84Melanogenesis_Homo sapiens_hsa049160.86746679
85Sulfur metabolism_Homo sapiens_hsa009200.85596599
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.83778687
87Cyanoamino acid metabolism_Homo sapiens_hsa004600.81591400
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80644248
89Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.76623960
90B cell receptor signaling pathway_Homo sapiens_hsa046620.75653951
91Ovarian steroidogenesis_Homo sapiens_hsa049130.75534293
92Axon guidance_Homo sapiens_hsa043600.73328795
93Circadian rhythm_Homo sapiens_hsa047100.73202071
94ErbB signaling pathway_Homo sapiens_hsa040120.69063399
95Mineral absorption_Homo sapiens_hsa049780.68586047
96Thyroid hormone synthesis_Homo sapiens_hsa049180.67891704
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.67388422
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66749054
99Choline metabolism in cancer_Homo sapiens_hsa052310.65684096
100Non-small cell lung cancer_Homo sapiens_hsa052230.65114786
101Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63671196
102Glycerolipid metabolism_Homo sapiens_hsa005610.63487790
103beta-Alanine metabolism_Homo sapiens_hsa004100.63014484
104Pancreatic secretion_Homo sapiens_hsa049720.62758934
105MAPK signaling pathway_Homo sapiens_hsa040100.61060347
106VEGF signaling pathway_Homo sapiens_hsa043700.60413863
107Huntingtons disease_Homo sapiens_hsa050160.58898520
108Dilated cardiomyopathy_Homo sapiens_hsa054140.58731215
109Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58337916
110Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58292957
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.57428633
112RNA degradation_Homo sapiens_hsa030180.56980626
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.56843265
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.56754947
115Dorso-ventral axis formation_Homo sapiens_hsa043200.56315027
116Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.56166808
117Rheumatoid arthritis_Homo sapiens_hsa053230.56100999
118Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54714874
119Allograft rejection_Homo sapiens_hsa053300.53551091
120Metabolic pathways_Homo sapiens_hsa011000.52765109
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52274672
122Inositol phosphate metabolism_Homo sapiens_hsa005620.51305515
123T cell receptor signaling pathway_Homo sapiens_hsa046600.50336433
124Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49553105
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.49203311
126Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.47894215
127Oocyte meiosis_Homo sapiens_hsa041140.47858102
128Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.47193500
129African trypanosomiasis_Homo sapiens_hsa051430.46560708
130Purine metabolism_Homo sapiens_hsa002300.45578922
131Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45560645
132Autoimmune thyroid disease_Homo sapiens_hsa053200.45444402
133Insulin signaling pathway_Homo sapiens_hsa049100.44919572
134Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43354547
135Central carbon metabolism in cancer_Homo sapiens_hsa052300.42893904
136Steroid biosynthesis_Homo sapiens_hsa001000.42805851
137One carbon pool by folate_Homo sapiens_hsa006700.42706674
138Vitamin digestion and absorption_Homo sapiens_hsa049770.41624709
139Adipocytokine signaling pathway_Homo sapiens_hsa049200.41610213
140Butanoate metabolism_Homo sapiens_hsa006500.41569409
141Phagosome_Homo sapiens_hsa041450.41292190
142Rap1 signaling pathway_Homo sapiens_hsa040150.41134727
143Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40921117
144Endometrial cancer_Homo sapiens_hsa052130.40599632
145Prolactin signaling pathway_Homo sapiens_hsa049170.39481529
146Histidine metabolism_Homo sapiens_hsa003400.39191150
147Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38679794
148SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37483475
149Thyroid hormone signaling pathway_Homo sapiens_hsa049190.36366024
150Glycerophospholipid metabolism_Homo sapiens_hsa005640.36208046
151Alcoholism_Homo sapiens_hsa050340.35735323
152Ras signaling pathway_Homo sapiens_hsa040140.35643374
153Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34812895
154Chemokine signaling pathway_Homo sapiens_hsa040620.33801009
155Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32694382
156Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32182954
157Acute myeloid leukemia_Homo sapiens_hsa052210.31259253
158Platelet activation_Homo sapiens_hsa046110.31101096
159mTOR signaling pathway_Homo sapiens_hsa041500.29206714
160Fatty acid degradation_Homo sapiens_hsa000710.28086359
161Renal cell carcinoma_Homo sapiens_hsa052110.27470677

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