MS4A18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vitamin A metabolic process (GO:0006776)6.92560882
2regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)6.75316390
3flavonoid metabolic process (GO:0009812)5.96736041
4actin filament depolymerization (GO:0030042)5.87765808
5sulfate transmembrane transport (GO:1902358)5.77788737
6drug catabolic process (GO:0042737)5.73242382
7adhesion of symbiont to host cell (GO:0044650)5.69040475
8virion attachment to host cell (GO:0019062)5.69040475
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.53632551
10phospholipid efflux (GO:0033700)5.28612608
11digestive system process (GO:0022600)5.27995060
12protein-lipid complex subunit organization (GO:0071825)5.25997236
13positive regulation of triglyceride lipase activity (GO:0061365)5.23236601
14positive regulation of lipoprotein lipase activity (GO:0051006)5.23236601
15regulation of triglyceride catabolic process (GO:0010896)5.20397320
16regulation of cholesterol esterification (GO:0010872)5.16915727
17regulation of guanylate cyclase activity (GO:0031282)5.11779878
18lipoprotein metabolic process (GO:0042157)5.10321326
19bundle of His cell to Purkinje myocyte communication (GO:0086069)4.99819844
20plasma lipoprotein particle assembly (GO:0034377)4.97184442
21sulfate transport (GO:0008272)4.81034231
22purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.80985536
233-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.80985536
24cytidine deamination (GO:0009972)4.77060948
25cytidine metabolic process (GO:0046087)4.77060948
26cytidine catabolic process (GO:0006216)4.77060948
27adhesion of symbiont to host (GO:0044406)4.72138334
28modified amino acid transport (GO:0072337)4.71157939
29protein-lipid complex assembly (GO:0065005)4.69954432
30regulation of cellular extravasation (GO:0002691)4.58915946
31hormone catabolic process (GO:0042447)4.52440107
32glucose 6-phosphate metabolic process (GO:0051156)4.42502775
33regulation of lipoprotein metabolic process (GO:0050746)4.36211419
34sulfur compound transport (GO:0072348)4.36056386
35cholesterol efflux (GO:0033344)4.34687505
36very-low-density lipoprotein particle assembly (GO:0034379)4.32177254
37cellular response to hepatocyte growth factor stimulus (GO:0035729)4.28401459
38response to hepatocyte growth factor (GO:0035728)4.28401459
39bile acid and bile salt transport (GO:0015721)4.22841281
40regulation of bile acid biosynthetic process (GO:0070857)4.22519430
41diacylglycerol metabolic process (GO:0046339)4.18545654
42vitamin transmembrane transport (GO:0035461)4.18076768
43fructose metabolic process (GO:0006000)4.16924953
44digestion (GO:0007586)4.05913702
45transepithelial transport (GO:0070633)4.04861499
46NADH metabolic process (GO:0006734)4.02642622
47epoxygenase P450 pathway (GO:0019373)4.01408025
48UDP-N-acetylglucosamine metabolic process (GO:0006047)4.01145740
49intestinal epithelial cell development (GO:0060576)3.97861666
50desmosome organization (GO:0002934)3.94875303
51cholesterol homeostasis (GO:0042632)3.94418212
52drug metabolic process (GO:0017144)3.93370471
53negative regulation of lipase activity (GO:0060192)3.92578193
54glutamine family amino acid biosynthetic process (GO:0009084)3.91734292
55sterol homeostasis (GO:0055092)3.91039081
56peptide hormone processing (GO:0016486)3.90134966
57positive regulation of glycoprotein biosynthetic process (GO:0010560)3.88960243
58homocysteine metabolic process (GO:0050667)3.85921191
59cholesterol transport (GO:0030301)3.85352920
60sterol transport (GO:0015918)3.85352920
61lipoprotein transport (GO:0042953)3.77848788
62membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.77744317
63transcytosis (GO:0045056)3.77696067
64L-ascorbic acid metabolic process (GO:0019852)3.76691045
65drinking behavior (GO:0042756)3.75332375
66sperm capacitation (GO:0048240)3.70331177
67regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.69836999
68positive regulation of guanylate cyclase activity (GO:0031284)3.68557956
69fat-soluble vitamin biosynthetic process (GO:0042362)3.68302181
70negative regulation of cholesterol transport (GO:0032375)3.68287322
71negative regulation of sterol transport (GO:0032372)3.68287322
72negative regulation of fatty acid biosynthetic process (GO:0045717)3.68195851
73peptide catabolic process (GO:0043171)3.65969029
74regulation of triglyceride metabolic process (GO:0090207)3.63433750
75positive regulation of respiratory burst (GO:0060267)3.62990390
76phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.61595097
77reverse cholesterol transport (GO:0043691)3.58801004
78antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.55831539
79bicarbonate transport (GO:0015701)3.54206141
80response to hydroperoxide (GO:0033194)3.53651423
81positive regulation of fatty acid biosynthetic process (GO:0045723)3.51913575
82calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.51319749
83low-density lipoprotein particle remodeling (GO:0034374)3.51037326
84urea cycle (GO:0000050)3.48112230
85urea metabolic process (GO:0019627)3.48112230
86exogenous drug catabolic process (GO:0042738)3.46976145
87positive regulation of triglyceride metabolic process (GO:0090208)3.45500065
88phenylpropanoid metabolic process (GO:0009698)3.44930121
89regulation of digestive system process (GO:0044058)3.42153249
90pyrimidine ribonucleoside catabolic process (GO:0046133)3.41021023
91positive regulation of glycoprotein metabolic process (GO:1903020)3.40251956
92sulfation (GO:0051923)3.37972009
93antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.37932380
94oligosaccharide catabolic process (GO:0009313)3.37541271
95maintenance of gastrointestinal epithelium (GO:0030277)3.37531270
96disruption of cells of other organism (GO:0044364)3.37310116
97killing of cells of other organism (GO:0031640)3.37310116
98regulation of systemic arterial blood pressure (GO:0003073)3.34816132
99cellular response to nitric oxide (GO:0071732)3.34671688
100cellular response to zinc ion (GO:0071294)3.33674065
101glomerular filtration (GO:0003094)3.33647222
102antibacterial humoral response (GO:0019731)3.33627930
103membrane repolarization during action potential (GO:0086011)3.32148626
104activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO3.32033007
105antimicrobial humoral response (GO:0019730)3.30677332
106auditory receptor cell differentiation (GO:0042491)3.29491379
107innate immune response in mucosa (GO:0002227)3.29124737
108primary alcohol catabolic process (GO:0034310)3.28475810
109regulation of systemic arterial blood pressure by hormone (GO:0001990)3.28332332
110regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.28332332
111endocrine process (GO:0050886)3.28332332
112defense response to fungus (GO:0050832)3.26910058
113cellular glucuronidation (GO:0052695)3.26591166
114phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.25122841
115high-density lipoprotein particle remodeling (GO:0034375)3.24461974
116ethanol metabolic process (GO:0006067)3.21279922
117plasma lipoprotein particle clearance (GO:0034381)3.20895090
118receptor guanylyl cyclase signaling pathway (GO:0007168)3.19975661
119regulation of cholesterol homeostasis (GO:2000188)3.18919712
120antigen processing and presentation of endogenous antigen (GO:0019883)3.18892768
121acylglycerol homeostasis (GO:0055090)3.18825428
122triglyceride homeostasis (GO:0070328)3.18825428
123protein-lipid complex remodeling (GO:0034368)3.16412139
124macromolecular complex remodeling (GO:0034367)3.16412139
125plasma lipoprotein particle remodeling (GO:0034369)3.16412139
126ventricular cardiac muscle cell action potential (GO:0086005)3.12027513
127hepatocyte apoptotic process (GO:0097284)3.11542729
128positive regulation of lipid catabolic process (GO:0050996)3.11062246
129plasma lipoprotein particle organization (GO:0071827)3.10972349
130polyol transport (GO:0015791)3.10613664
131regulation of cGMP biosynthetic process (GO:0030826)3.08320818
132removal of superoxide radicals (GO:0019430)3.07810209
133cellular response to superoxide (GO:0071451)3.07810209
134cellular response to oxygen radical (GO:0071450)3.07810209
135fat-soluble vitamin metabolic process (GO:0006775)3.07117386
136cellular response to reactive nitrogen species (GO:1902170)3.05270570
137response to nitric oxide (GO:0071731)3.01643023
138vitamin transport (GO:0051180)3.01290029
139arginine metabolic process (GO:0006525)2.99833997
140regulation of fatty acid biosynthetic process (GO:0042304)2.98366816
141regulation of sterol transport (GO:0032371)2.97026890
142regulation of cholesterol transport (GO:0032374)2.97026890
143renal filtration (GO:0097205)2.95525458
144intestinal absorption (GO:0050892)12.0255908
145intestinal cholesterol absorption (GO:0030299)11.4179487
146angiotensin maturation (GO:0002003)10.4490865

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.30961707
2CDX2_20551321_ChIP-Seq_CACO-2_Human6.11584823
3HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.95291415
4SOX2_27498859_Chip-Seq_STOMACH_Mouse3.88609329
5ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.41126914
6GATA4_25053715_ChIP-Seq_YYC3_Human3.31235535
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.19616530
8PPARA_22158963_ChIP-Seq_LIVER_Mouse3.18510235
9TRIM28_21343339_ChIP-Seq_HEK293_Human3.03474819
10SOX2_20726797_ChIP-Seq_SW620_Human3.02141343
11GATA6_25053715_ChIP-Seq_YYC3_Human2.90316997
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.87629017
13RXR_22158963_ChIP-Seq_LIVER_Mouse2.66512761
14IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.66030315
15LXR_22158963_ChIP-Seq_LIVER_Mouse2.55916683
16SRY_22984422_ChIP-ChIP_TESTIS_Rat2.41650406
17CDX2_19796622_ChIP-Seq_MESCs_Mouse2.41029450
18PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.40617999
19STAT6_21828071_ChIP-Seq_BEAS2B_Human2.17106070
20SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.10733512
21EGR1_23403033_ChIP-Seq_LIVER_Mouse1.84230421
22STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.83607817
23BP1_19119308_ChIP-ChIP_Hs578T_Human1.83421717
24PPAR_26484153_Chip-Seq_NCI-H1993_Human1.83324479
25KLF5_25053715_ChIP-Seq_YYC3_Human1.77117550
26NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.76125811
27TCF4_18268006_ChIP-ChIP_LS174T_Human1.68922803
28VDR_22108803_ChIP-Seq_LS180_Human1.63973166
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.63599733
30CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.61838854
31KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.55000160
32NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.51601353
33KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.50762960
34CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.50512290
35RACK7_27058665_Chip-Seq_MCF-7_Human1.48349765
36SA1_27219007_Chip-Seq_Bcells_Human1.46399183
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.43692505
38HNF4A_19822575_ChIP-Seq_HepG2_Human1.42611307
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.42538636
40RUNX1_27514584_Chip-Seq_MCF-7_Human1.39393889
41GATA2_19941826_ChIP-Seq_K562_Human1.36456492
42FOXA1_25552417_ChIP-Seq_VCAP_Human1.35639178
43FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.35464417
44ATF3_27146783_Chip-Seq_COLON_Human1.32016422
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25824919
46RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25441831
47IRF8_21731497_ChIP-ChIP_J774_Mouse1.23906347
48BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.23264222
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.22860830
50FOXO3_23340844_ChIP-Seq_DLD1_Human1.22848524
51GATA1_26923725_Chip-Seq_HPCs_Mouse1.21616101
52ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.20665170
53DROSHA_22980978_ChIP-Seq_HELA_Human1.20274183
54CTCF_27219007_Chip-Seq_Bcells_Human1.19531451
55JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.18105518
56EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.16402810
57ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.14414752
58FOXA2_19822575_ChIP-Seq_HepG2_Human1.13979798
59CDX2_22108803_ChIP-Seq_LS180_Human1.13573732
60PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13368709
61BCAT_22108803_ChIP-Seq_LS180_Human1.12674553
62AR_21909140_ChIP-Seq_LNCAP_Human1.11937767
63MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.10161953
64TAF2_19829295_ChIP-Seq_ESCs_Human1.09017280
65NANOG_20526341_ChIP-Seq_ESCs_Human1.07913634
66KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07490874
67CEBPB_22108803_ChIP-Seq_LS180_Human1.07316076
68HIF1A_21447827_ChIP-Seq_MCF-7_Human1.06656331
69FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.06465074
70CREB1_26743006_Chip-Seq_LNCaP_Human1.06410997
71SALL4_18804426_ChIP-ChIP_XEN_Mouse1.05219910
72PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.04877744
73BCOR_27268052_Chip-Seq_Bcells_Human1.04593274
74EZH2_22144423_ChIP-Seq_EOC_Human1.03084881
75ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.02151431
76FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.00992351
77RXR_22108803_ChIP-Seq_LS180_Human0.99357606
78GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.99040152
79EGR1_19032775_ChIP-ChIP_M12_Human0.98851259
80RAD21_21589869_ChIP-Seq_MESCs_Mouse0.98712266
81P300_27268052_Chip-Seq_Bcells_Human0.98640506
82TCF3_18692474_ChIP-Seq_MEFs_Mouse0.98187285
83LXR_22292898_ChIP-Seq_THP-1_Human0.97800145
84FOXA1_21572438_ChIP-Seq_LNCaP_Human0.97679999
85CLOCK_20551151_ChIP-Seq_293T_Human0.97521104
86ETV2_25802403_ChIP-Seq_MESCs_Mouse0.95520990
87CTCF_20526341_ChIP-Seq_ESCs_Human0.95380469
88NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94987199
89SOX2_22085726_ChIP-Seq_NPCs_Mouse0.94342004
90SMAD3_21741376_ChIP-Seq_HESCs_Human0.93697164
91ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93535888
92SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.93414346
93SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.93414346
94FOXA1_27270436_Chip-Seq_PROSTATE_Human0.92639559
95FOXA1_25329375_ChIP-Seq_VCAP_Human0.92639559
96GATA1_22025678_ChIP-Seq_K562_Human0.92318091
97CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92102056
98E2F1_20622854_ChIP-Seq_HELA_Human0.91854212
99THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91087650
100ESR1_21235772_ChIP-Seq_MCF-7_Human0.90160989
101HNFA_21074721_ChIP-Seq_CACO-2_Human0.88713814
102FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.88305368
103RARG_19884340_ChIP-ChIP_MEFs_Mouse0.88142203
104ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.87444224
105CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.86507772
106NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85879020
107SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.85551141
108FOXH1_21741376_ChIP-Seq_ESCs_Human0.84625208
109SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84433172
110P68_20966046_ChIP-Seq_HELA_Human0.84157541
111PHF8_20622853_ChIP-Seq_HELA_Human0.83496488
112CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.82939326
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.82022305
114AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.81967193
115PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.81895673
116FOXM1_26456572_ChIP-Seq_MCF-7_Human0.81739659
117SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.81705648
118TP63_22573176_ChIP-Seq_HFKS_Human0.81627895
119WDR5_24793694_ChIP-Seq_LNCAP_Human0.81384654
120TET1_21451524_ChIP-Seq_MESCs_Mouse0.80991098
121BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.80847177
122POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.80546193
123NFYA_21822215_ChIP-Seq_K562_Human0.80544377
124CBP_21632823_ChIP-Seq_H3396_Human0.80510990
125RAC3_21632823_ChIP-Seq_H3396_Human0.80479652
126CTCF_27219007_Chip-Seq_ERYTHROID_Human0.80447365
127ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.80134384
128CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.80017490
129TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.79783608
130PRDM14_20953172_ChIP-Seq_ESCs_Human0.79606372
131NR3C1_21868756_ChIP-Seq_MCF10A_Human0.78983353
132PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.78905289
133UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.78706872
134LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.78500330
135ERA_21632823_ChIP-Seq_H3396_Human0.78493185
136OCT4_18692474_ChIP-Seq_MEFs_Mouse0.78122919
137EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.77202171
138JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.76613624
139P63_26484246_Chip-Seq_KERATINOCYTES_Human0.75944557
140SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.75921860
141KAP1_22055183_ChIP-Seq_ESCs_Mouse0.75741143
142PHF8_20622854_ChIP-Seq_HELA_Human0.75457202
143BCL6_27268052_Chip-Seq_Bcells_Human0.75226669
144MYC_19829295_ChIP-Seq_ESCs_Human0.75126589
145SOX9_24532713_ChIP-Seq_HFSC_Mouse0.74646453
146SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.73298579
147PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.73288544
148JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.73279053
149GATA3_24758297_ChIP-Seq_MCF-7_Human0.73130092
150RARA_24833708_ChIP-Seq_LIVER_Mouse0.72997945

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis9.63312437
2MP0001666_abnormal_nutrient_absorption5.61931475
3MP0010234_abnormal_vibrissa_follicle5.18195796
4MP0002139_abnormal_hepatobiliary_system3.89076754
5MP0009840_abnormal_foam_cell3.80134210
6MP0000462_abnormal_digestive_system3.49131908
7MP0004264_abnormal_extraembryonic_tissu3.26433320
8MP0005085_abnormal_gallbladder_physiolo3.22917328
9MP0003252_abnormal_bile_duct2.93658255
10MP0003866_abnormal_defecation2.79553913
11MP0009379_abnormal_foot_pigmentation2.75448424
12MP0003183_abnormal_peptide_metabolism2.74883539
13MP0008875_abnormal_xenobiotic_pharmacok2.62902598
14MP0010329_abnormal_lipoprotein_level2.54863730
15MP0002822_catalepsy2.17244260
16MP0001873_stomach_inflammation2.16838383
17MP0001663_abnormal_digestive_system2.12768139
18MP0005381_digestive/alimentary_phenotyp2.03995360
19MP0004019_abnormal_vitamin_homeostasis2.03446691
20MP0004147_increased_porphyrin_level2.01755726
21MP0010155_abnormal_intestine_physiology1.92251464
22MP0000490_abnormal_crypts_of1.92049012
23MP0001664_abnormal_digestion1.91604627
24MP0003300_gastrointestinal_ulcer1.88745301
25MP0005365_abnormal_bile_salt1.81647662
26MP0005084_abnormal_gallbladder_morpholo1.77778319
27MP0000537_abnormal_urethra_morphology1.72036220
28MP0004858_abnormal_nervous_system1.71857605
29MP0000477_abnormal_intestine_morphology1.70616327
30MP0008004_abnormal_stomach_pH1.66557865
31MP0002254_reproductive_system_inflammat1.66293178
32MP0005377_hearing/vestibular/ear_phenot1.61952665
33MP0003878_abnormal_ear_physiology1.61952665
34MP0010352_gastrointestinal_tract_polyps1.61865565
35MP0003879_abnormal_hair_cell1.57353900
36MP0000538_abnormal_urinary_bladder1.54148271
37MP0002089_abnormal_postnatal_growth/wei1.39383643
38MP0005448_abnormal_energy_balance1.37299950
39MP0003705_abnormal_hypodermis_morpholog1.32940556
40MP0002277_abnormal_respiratory_mucosa1.29284709
41MP0006054_spinal_hemorrhage1.25922104
42MP0005670_abnormal_white_adipose1.21743951
43MP0004043_abnormal_pH_regulation1.20848286
44MP0002796_impaired_skin_barrier1.20713852
45MP0002971_abnormal_brown_adipose1.18674661
46MP0003191_abnormal_cellular_cholesterol1.17411836
47MP0001501_abnormal_sleep_pattern1.15912094
48MP0005174_abnormal_tail_pigmentation1.15340760
49MP0005332_abnormal_amino_acid1.13619412
50MP0003806_abnormal_nucleotide_metabolis1.11027583
51MP0004782_abnormal_surfactant_physiolog1.06614853
52MP0009643_abnormal_urine_homeostasis1.05511682
53MP0000604_amyloidosis1.03399491
54MP0001958_emphysema1.02728342
55MP0010678_abnormal_skin_adnexa0.99313410
56MP0000249_abnormal_blood_vessel0.98813449
57MP0001485_abnormal_pinna_reflex0.98598584
58MP0001756_abnormal_urination0.94952448
59MP0002118_abnormal_lipid_homeostasis0.94421519
60MP0008872_abnormal_physiological_respon0.93002953
61MP0005535_abnormal_body_temperature0.92145634
62MP0002734_abnormal_mechanical_nocicepti0.91165039
63MP0003718_maternal_effect0.86665131
64MP0004145_abnormal_muscle_electrophysio0.86294380
65MP0005451_abnormal_body_composition0.84185077
66MP0000566_synostosis0.84136090
67MP0003453_abnormal_keratinocyte_physiol0.83579665
68MP0002876_abnormal_thyroid_physiology0.83094631
69MP0009115_abnormal_fat_cell0.82780430
70MP0003329_amyloid_beta_deposits0.82335610
71MP0003868_abnormal_feces_composition0.81743517
72MP0004947_skin_inflammation0.81119582
73MP0000609_abnormal_liver_physiology0.80960247
74MP0009697_abnormal_copulation0.80178649
75MP0001845_abnormal_inflammatory_respons0.79851898
76MP0001835_abnormal_antigen_presentation0.79093947
77MP0004270_analgesia0.77432516
78MP0000467_abnormal_esophagus_morphology0.75784029
79MP0005166_decreased_susceptibility_to0.73348496
80MP0003950_abnormal_plasma_membrane0.71998087
81MP0000516_abnormal_urinary_system0.71319196
82MP0005367_renal/urinary_system_phenotyp0.71319196
83MP0000470_abnormal_stomach_morphology0.70932230
84MP0005501_abnormal_skin_physiology0.70509171
85MP0001765_abnormal_ion_homeostasis0.69539411
86MP0002098_abnormal_vibrissa_morphology0.68844380
87MP0005167_abnormal_blood-brain_barrier0.67486439
88MP0002998_abnormal_bone_remodeling0.65562418
89MP0001188_hyperpigmentation0.65204257
90MP0000681_abnormal_thyroid_gland0.64660691
91MP0005395_other_phenotype0.64050580
92MP0001849_ear_inflammation0.63027971
93MP0000613_abnormal_salivary_gland0.62571406
94MP0005666_abnormal_adipose_tissue0.61962471
95MP0000427_abnormal_hair_cycle0.61676090
96MP0005025_abnormal_response_to0.61257725
97MP0002078_abnormal_glucose_homeostasis0.60607256
98MP0009053_abnormal_anal_canal0.60551664
99MP0005319_abnormal_enzyme/_coenzyme0.59521235
100MP0005387_immune_system_phenotype0.58481719
101MP0001790_abnormal_immune_system0.58481719
102MP0008469_abnormal_protein_level0.58233408
103MP0009333_abnormal_splenocyte_physiolog0.57858299
104MP0002136_abnormal_kidney_physiology0.56864534
105MP0003953_abnormal_hormone_level0.55966655
106MP0005334_abnormal_fat_pad0.54852884
107MP0000230_abnormal_systemic_arterial0.54031289
108MP0001216_abnormal_epidermal_layer0.53831755
109MP0005409_darkened_coat_color0.53426640
110MP0002138_abnormal_hepatobiliary_system0.53341980
111MP0002896_abnormal_bone_mineralization0.52018543
112MP0003436_decreased_susceptibility_to0.51629626
113MP0002638_abnormal_pupillary_reflex0.51476993
114MP0000015_abnormal_ear_pigmentation0.51114662
115MP0005636_abnormal_mineral_homeostasis0.50905599
116MP0001533_abnormal_skeleton_physiology0.50255813
117MP0003724_increased_susceptibility_to0.48497774
118MP0005058_abnormal_lysosome_morphology0.48492175
119MP0009384_cardiac_valve_regurgitation0.47722848
120MP0009642_abnormal_blood_homeostasis0.47687153
121MP0000678_abnormal_parathyroid_gland0.46158326
122MP0009765_abnormal_xenobiotic_induced0.45445967
123MP0009780_abnormal_chondrocyte_physiolo0.44695340
124MP0001764_abnormal_homeostasis0.44415649
125MP0005266_abnormal_metabolism0.42565174
126MP0001191_abnormal_skin_condition0.40766751
127MP0010386_abnormal_urinary_bladder0.40354867
128MP0005310_abnormal_salivary_gland0.40331349
129MP0009785_altered_susceptibility_to0.40199842
130MP0003938_abnormal_ear_development0.40095541
131MP0005584_abnormal_enzyme/coenzyme_acti0.39791334
132MP0006082_CNS_inflammation0.39471198
133MP0003638_abnormal_response/metabolism_0.39083506
134MP0003693_abnormal_embryo_hatching0.38958841
135MP0002060_abnormal_skin_morphology0.37555454
136MP0000377_abnormal_hair_follicle0.36321104
137MP0003283_abnormal_digestive_organ0.35751881
138MP0010771_integument_phenotype0.35344267
139MP0005464_abnormal_platelet_physiology0.33841052

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)8.54350075
2Acanthocytosis (HP:0001927)6.67563006
3Abnormality of glutamine family amino acid metabolism (HP:0010902)6.66311363
4Malnutrition (HP:0004395)6.22182918
5Hypobetalipoproteinemia (HP:0003563)6.16179627
6Right ventricular cardiomyopathy (HP:0011663)5.44446634
7Systemic lupus erythematosus (HP:0002725)5.24484911
8Hyperlipoproteinemia (HP:0010980)5.04575333
9Conjugated hyperbilirubinemia (HP:0002908)4.84156605
10Hydroxyprolinuria (HP:0003080)4.57319206
11Abnormality of proline metabolism (HP:0010907)4.57319206
12Congenital sensorineural hearing impairment (HP:0008527)4.25910609
13Autoimmune thrombocytopenia (HP:0001973)4.16806679
14Abnormality of pyrimidine metabolism (HP:0004353)4.03563477
15Ventricular fibrillation (HP:0001663)3.93627084
16Cupped ribs (HP:0000887)3.91117607
17Poikilocytosis (HP:0004447)3.88350442
18Fat malabsorption (HP:0002630)3.86719760
19Pigmentary retinal degeneration (HP:0001146)3.83463269
20Abdominal distention (HP:0003270)3.73660888
21Vascular calcification (HP:0004934)3.70678715
22Chronic diarrhea (HP:0002028)3.52342014
23Hypolipoproteinemia (HP:0010981)3.42196323
24Syncope (HP:0001279)3.38880610
25Cardiovascular calcification (HP:0011915)3.24043753
26Glycosuria (HP:0003076)3.18688342
27Abnormality of urine glucose concentration (HP:0011016)3.18688342
28Abnormality of magnesium homeostasis (HP:0004921)3.17764506
29Gastrointestinal dysmotility (HP:0002579)3.16043687
30Widely patent fontanelles and sutures (HP:0004492)3.15233308
31Abnormality of the vitamin B12 metabolism (HP:0004341)3.14862103
32Autoimmune hemolytic anemia (HP:0001890)3.08083521
33Abnormality of small intestinal villus morphology (HP:0011472)3.06165300
34Villous atrophy (HP:0011473)3.06165300
35Facial shape deformation (HP:0011334)3.03987743
36Potter facies (HP:0002009)3.03987743
37Flat acetabular roof (HP:0003180)3.01053666
38Vacuolated lymphocytes (HP:0001922)3.00431295
39Hyperphosphatemia (HP:0002905)2.98838499
40Abnormality of monocarboxylic acid metabolism (HP:0010996)2.97968843
41Woolly hair (HP:0002224)2.95321316
42Glomerulonephritis (HP:0000099)2.95036859
43Abnormality of nucleobase metabolism (HP:0010932)2.93028400
44Dehydration (HP:0001944)2.92554963
45Abnormality of vitamin B metabolism (HP:0004340)2.92394908
46Hyperglycinuria (HP:0003108)2.89022760
47Increased purine levels (HP:0004368)2.86650729
48Hyperuricemia (HP:0002149)2.86650729
49Palpitations (HP:0001962)2.85963962
50Intrahepatic cholestasis (HP:0001406)2.85330168
51Abnormality of macrophages (HP:0004311)2.83371655
52Complement deficiency (HP:0004431)2.82268655
53Abnormal biliary tract morphology (HP:0012440)2.79265731
54Abnormality of complement system (HP:0005339)2.72711521
55Xanthomatosis (HP:0000991)2.67148190
56Periodontitis (HP:0000704)2.65993842
57Micronodular cirrhosis (HP:0001413)2.65896019
58Abnormal tarsal ossification (HP:0008369)2.63270083
59Hyperphosphaturia (HP:0003109)2.60291355
60Hypercholesterolemia (HP:0003124)2.59482472
61Nephrolithiasis (HP:0000787)2.58218867
62Pancreatitis (HP:0001733)2.58180676
63Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.57463739
64Pustule (HP:0200039)2.54570300
65Hyperglycinemia (HP:0002154)2.53666259
66Severe combined immunodeficiency (HP:0004430)2.51651390
67Increased mean platelet volume (HP:0011877)2.50613454
68Alkalosis (HP:0001948)2.50182440
69Rectal prolapse (HP:0002035)2.49952906
70Abnormality of vitamin metabolism (HP:0100508)2.49650213
71Prolonged QT interval (HP:0001657)2.45339789
72Decreased circulating renin level (HP:0003351)2.44039373
73Abnormal urine phosphate concentration (HP:0012599)2.43220712
74Mesangial abnormality (HP:0001966)2.41732418
75Nausea (HP:0002018)2.41535652
76Nephritis (HP:0000123)2.40494353
77Abnormality of aspartate family amino acid metabolism (HP:0010899)2.40331579
78Reticulocytosis (HP:0001923)2.37028526
79Metabolic alkalosis (HP:0200114)2.34383367
80Combined immunodeficiency (HP:0005387)2.32970708
81Increased IgE level (HP:0003212)2.28958352
82Tetany (HP:0001281)2.28521710
83Wide cranial sutures (HP:0010537)2.27618225
84Confusion (HP:0001289)2.27289728
85Premature loss of primary teeth (HP:0006323)2.26817856
86Abnormality of purine metabolism (HP:0004352)2.25187502
87Abnormality of the gastric mucosa (HP:0004295)2.24228774
88Posterior subcapsular cataract (HP:0007787)2.23047675
89Abnormal platelet volume (HP:0011876)2.22379803
90Hyperbilirubinemia (HP:0002904)2.21780547
91Pili torti (HP:0003777)2.20650645
92Delayed CNS myelination (HP:0002188)2.15659169
93Mildly elevated creatine phosphokinase (HP:0008180)2.15538537
94Abnormality of sulfur amino acid metabolism (HP:0004339)2.14570008
95Gout (HP:0001997)2.13731660
96Polycythemia (HP:0001901)2.11890799
97Abnormality of chloride homeostasis (HP:0011422)2.09310075
98Myopathic facies (HP:0002058)2.08097049
99Steatorrhea (HP:0002570)2.07805262
100Hypomagnesemia (HP:0002917)2.07724612
101Late onset (HP:0003584)2.07453161
102Hyperparathyroidism (HP:0000843)2.05442625
103Biliary tract neoplasm (HP:0100574)2.04301211
104Hypoalbuminemia (HP:0003073)2.02448231
105Abnormal albumin level (HP:0012116)2.02448231
106Amyloidosis (HP:0011034)2.01723640
107Abnormality of the 1st metacarpal (HP:0010009)2.01152941
108Cholecystitis (HP:0001082)2.00693606
109Abnormal gallbladder physiology (HP:0012438)2.00693606
110Male infertility (HP:0003251)1.99808379
111Abnormality of glycine metabolism (HP:0010895)1.99654977
112Abnormality of serine family amino acid metabolism (HP:0010894)1.99654977
113Cheilitis (HP:0100825)1.99180037
114Proximal tubulopathy (HP:0000114)1.97298268
115Gingival bleeding (HP:0000225)1.96517378
116Epidermoid cyst (HP:0200040)1.96478413
117Goiter (HP:0000853)1.96310794
118Hypotension (HP:0002615)1.95114906
119Hyperammonemia (HP:0001987)1.94584287
120Eczematoid dermatitis (HP:0000976)1.94475135
121Fragile skin (HP:0001030)1.92628926
122Neoplasm of the rectum (HP:0100743)1.91195961
123Chronic otitis media (HP:0000389)1.90090199
124Ventricular arrhythmia (HP:0004308)1.89079247
125Abnormality of renal excretion (HP:0011036)1.88781834
126Abnormal glucose tolerance (HP:0001952)1.88539273
127Abnormality of carpal bone ossification (HP:0006257)1.87204550
128Bundle branch block (HP:0011710)1.87101940
129Protuberant abdomen (HP:0001538)1.86907377
130Dysostosis multiplex (HP:0000943)1.84756764
131Thin bony cortex (HP:0002753)1.83751879
132Hemorrhage of the eye (HP:0011885)1.83095034
133Fragile nails (HP:0001808)1.82054901
134Hypophosphatemia (HP:0002148)1.81190404
135Metabolic acidosis (HP:0001942)1.81152043
136Abnormality of renin-angiotensin system (HP:0000847)1.80476271
137Progressive sensorineural hearing impairment (HP:0000408)1.80244966
138Mitral stenosis (HP:0001718)1.76551849
139Subcapsular cataract (HP:0000523)1.74637487
140Dicarboxylic aciduria (HP:0003215)1.71985773
141Abnormality of dicarboxylic acid metabolism (HP:0010995)1.71985773
142Peripheral demyelination (HP:0011096)1.70832059
143Hyperactive renin-angiotensin system (HP:0000841)1.68188821
144Abnormality of transition element cation homeostasis (HP:0011030)1.65329748
145Ulnar claw (HP:0001178)1.64381853
146Stomach cancer (HP:0012126)1.64154062
147Severe visual impairment (HP:0001141)1.64093738
148Renal tubular acidosis (HP:0001947)1.61925404
149Hypocalcemia (HP:0002901)1.61820837
150Segmental peripheral demyelination/remyelination (HP:0003481)1.60830590
151Loss of speech (HP:0002371)1.60388780

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIK3CG7.66488809
2LMTK26.86614533
3MUSK6.40954776
4ACVR1B6.14734127
5FRK4.58731016
6MST44.26978146
7PRKG24.05642426
8MST1R3.74654718
9RIPK13.54971997
10NME13.25939007
11GRK63.24163923
12PBK2.70151516
13MAP2K22.59906027
14MAP3K22.56077703
15EPHB22.44367609
16FGFR42.17122877
17MAP3K102.16152104
18NUAK12.02351893
19TTK1.86417681
20EPHA31.83350082
21AKT31.79581172
22PTK61.77150409
23PIK3CA1.65940440
24TESK11.63128437
25EPHA21.60365590
26MAP3K121.49355963
27MAP2K61.49295078
28MAP3K111.41481375
29ERN11.37360224
30TAOK11.34430678
31MYLK1.34355842
32TYK21.33666866
33KSR21.24470603
34ADRBK21.22063658
35STK241.18449902
36TESK21.17168440
37SCYL21.16721203
38BLK1.14172193
39NLK1.11442077
40BCKDK1.11431623
41MET1.10600242
42MAP3K81.03993682
43FGFR30.95449824
44IRAK30.92476237
45PRKCI0.91403743
46BMX0.84888610
47CDC42BPA0.84583431
48PTK20.84496312
49STK100.84371648
50ERBB20.83992176
51RIPK40.83837349
52MATK0.79717130
53FGFR20.78204998
54STK390.76145098
55DDR20.75245719
56MAP2K10.75198657
57EPHA40.74874387
58PRKAA20.73928538
59CASK0.73339512
60LIMK10.72340424
61JAK10.70103726
62EPHB10.68720388
63IRAK10.65082218
64ABL20.64512877
65FER0.59161703
66TBK10.58821610
67CAMK2D0.57892963
68MAP3K10.57401492
69MELK0.56285942
70IKBKE0.55770060
71MAPK110.53896514
72PAK40.53824966
73PKN20.52139151
74JAK30.52120191
75KIT0.50997369
76LATS10.50766270
77WNK30.50216452
78MAP4K10.48579069
79BRSK20.48336151
80ALK0.46898329
81PRKAA10.46777269
82PDPK10.46713695
83ZAP700.46381379
84NTRK30.44561367
85CAMK2G0.44527241
86MAP3K70.42274990
87PAK10.41689036
88STK30.40988391
89TAOK30.39154992
90CSK0.38394487
91CSF1R0.38101787
92OXSR10.37257118
93AURKB0.37195007
94MAPKAPK20.37105334
95CAMK2B0.37090010
96IRAK20.36967721
97SRC0.36284985
98PRKCA0.36046028
99ERBB40.35411188
100KDR0.34121459
101FGR0.33444666
102LRRK20.32364975
103MAP3K30.31925961
104NEK60.31362217
105CSNK1A10.31303257
106JAK20.31005941
107STK110.30942974
108TXK0.30747306
109PIM20.30547829
110ITK0.30345127
111STK40.28551752
112PRKCD0.27616487
113PRKCQ0.27561764
114PDGFRA0.27527029
115CDK190.27267489
116IRAK40.27208442
117ROCK10.26777387
118CDK60.26156875
119DAPK20.26129230
120MAP3K90.26004297
121INSRR0.25994878
122PDK10.25780735
123PRKCE0.25406538
124PRKACG0.25401898
125GSK3A0.25070577
126RET0.24978291
127MAPKAPK30.24795333
128EIF2AK10.23985241
129GRK10.23501719
130TNIK0.23257456
131LCK0.21570433
132IGF1R0.19111827
133DMPK0.18145097
134PAK20.17410042
135ICK0.17320165
136GRK50.16501261
137EEF2K0.16299076
138WNK40.16160219
139PAK30.15960197
140CSNK1E0.15809505
141PRKCZ0.15515732
142RPS6KA10.14718617
143PDK20.14606502

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049756.03025847
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.84694318
3Renin-angiotensin system_Homo sapiens_hsa046144.14862757
4Vitamin digestion and absorption_Homo sapiens_hsa049773.65329318
5Mineral absorption_Homo sapiens_hsa049783.50256321
6Sulfur metabolism_Homo sapiens_hsa009202.71374906
7Galactose metabolism_Homo sapiens_hsa000522.67965776
8Folate biosynthesis_Homo sapiens_hsa007902.48957752
9Starch and sucrose metabolism_Homo sapiens_hsa005002.47061528
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.42897452
11Carbohydrate digestion and absorption_Homo sapiens_hsa049732.38293207
12Maturity onset diabetes of the young_Homo sapiens_hsa049502.33722977
13Caffeine metabolism_Homo sapiens_hsa002322.32046680
14Histidine metabolism_Homo sapiens_hsa003402.29517933
15Protein digestion and absorption_Homo sapiens_hsa049742.24692597
16Fructose and mannose metabolism_Homo sapiens_hsa000512.18827883
17Bile secretion_Homo sapiens_hsa049762.06043854
18Asthma_Homo sapiens_hsa053101.79406221
19Glutathione metabolism_Homo sapiens_hsa004801.69015423
20Pentose and glucuronate interconversions_Homo sapiens_hsa000401.55666566
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.52910228
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.49940723
23Staphylococcus aureus infection_Homo sapiens_hsa051501.46889377
24Tryptophan metabolism_Homo sapiens_hsa003801.44942071
25Arginine biosynthesis_Homo sapiens_hsa002201.37419429
26Fatty acid degradation_Homo sapiens_hsa000711.34963541
27Allograft rejection_Homo sapiens_hsa053301.29812575
28Glycerolipid metabolism_Homo sapiens_hsa005611.29468216
29Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.29183525
30PPAR signaling pathway_Homo sapiens_hsa033201.28085808
31Arginine and proline metabolism_Homo sapiens_hsa003301.24982760
32Nitrogen metabolism_Homo sapiens_hsa009101.24759834
33Autoimmune thyroid disease_Homo sapiens_hsa053201.22883549
34Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.22402262
35Graft-versus-host disease_Homo sapiens_hsa053321.21156245
36Cyanoamino acid metabolism_Homo sapiens_hsa004601.21082219
37Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.15760201
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.13915038
39Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.13764964
40Sphingolipid metabolism_Homo sapiens_hsa006001.09975862
41Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.07003059
42Type I diabetes mellitus_Homo sapiens_hsa049401.00395611
43Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.97682657
44Drug metabolism - other enzymes_Homo sapiens_hsa009830.97430298
45Pentose phosphate pathway_Homo sapiens_hsa000300.94402905
46Pyruvate metabolism_Homo sapiens_hsa006200.93569293
47Chemical carcinogenesis_Homo sapiens_hsa052040.92846577
48Complement and coagulation cascades_Homo sapiens_hsa046100.84668221
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.83449613
50Other glycan degradation_Homo sapiens_hsa005110.83171037
51beta-Alanine metabolism_Homo sapiens_hsa004100.79832126
52Intestinal immune network for IgA production_Homo sapiens_hsa046720.75633333
53ABC transporters_Homo sapiens_hsa020100.74197325
54Carbon metabolism_Homo sapiens_hsa012000.73354173
55Antigen processing and presentation_Homo sapiens_hsa046120.68405981
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65722212
57Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64887658
58Thyroid hormone synthesis_Homo sapiens_hsa049180.63144654
59Retinol metabolism_Homo sapiens_hsa008300.61327766
60alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.60704142
61Tight junction_Homo sapiens_hsa045300.59841255
62Steroid biosynthesis_Homo sapiens_hsa001000.57724926
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56256750
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.55849227
65Pancreatic secretion_Homo sapiens_hsa049720.54361556
66Alzheimers disease_Homo sapiens_hsa050100.52915090
67Leishmaniasis_Homo sapiens_hsa051400.52441453
68Oxidative phosphorylation_Homo sapiens_hsa001900.51480933
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49135131
70Parkinsons disease_Homo sapiens_hsa050120.47921157
71Arachidonic acid metabolism_Homo sapiens_hsa005900.47810121
72Primary bile acid biosynthesis_Homo sapiens_hsa001200.45875207
73Leukocyte transendothelial migration_Homo sapiens_hsa046700.41896207
74Gastric acid secretion_Homo sapiens_hsa049710.41151597
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40998638
76Butanoate metabolism_Homo sapiens_hsa006500.39975581
77Biosynthesis of amino acids_Homo sapiens_hsa012300.39082728
78Fatty acid elongation_Homo sapiens_hsa000620.38654143
79Fatty acid metabolism_Homo sapiens_hsa012120.38607092
80Steroid hormone biosynthesis_Homo sapiens_hsa001400.38596306
81Linoleic acid metabolism_Homo sapiens_hsa005910.38310468
82Renin secretion_Homo sapiens_hsa049240.37142473
83Hepatitis C_Homo sapiens_hsa051600.36917887
84Metabolic pathways_Homo sapiens_hsa011000.35553306
85Type II diabetes mellitus_Homo sapiens_hsa049300.31678414
86Viral myocarditis_Homo sapiens_hsa054160.30880478
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30765496
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30657685
89African trypanosomiasis_Homo sapiens_hsa051430.30533795
90Vibrio cholerae infection_Homo sapiens_hsa051100.29966708
91Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.28756714
92Salmonella infection_Homo sapiens_hsa051320.28527101
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.26954138
94Bladder cancer_Homo sapiens_hsa052190.26901807
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.26348886
96Toxoplasmosis_Homo sapiens_hsa051450.25721715
97Insulin resistance_Homo sapiens_hsa049310.25338727
98Thyroid cancer_Homo sapiens_hsa052160.22594994
99Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.22006240
100Ether lipid metabolism_Homo sapiens_hsa005650.21977166
101Vascular smooth muscle contraction_Homo sapiens_hsa042700.20062892
102Inositol phosphate metabolism_Homo sapiens_hsa005620.20044020
103Phenylalanine metabolism_Homo sapiens_hsa003600.19627271
104Fatty acid biosynthesis_Homo sapiens_hsa000610.18490929
105Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.18339636
106Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.17857121
107Huntingtons disease_Homo sapiens_hsa050160.17458179
108Peroxisome_Homo sapiens_hsa041460.17089591
109Tyrosine metabolism_Homo sapiens_hsa003500.16987622
110Cocaine addiction_Homo sapiens_hsa050300.16613347
111Pertussis_Homo sapiens_hsa051330.16431903
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.16183156
113Sulfur relay system_Homo sapiens_hsa041220.15602134
114Glucagon signaling pathway_Homo sapiens_hsa049220.15546570
115NOD-like receptor signaling pathway_Homo sapiens_hsa046210.14887454
116Legionellosis_Homo sapiens_hsa051340.14639237
117Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.14516205
118GnRH signaling pathway_Homo sapiens_hsa049120.11156570
119Lysine degradation_Homo sapiens_hsa003100.10516311
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.09317866
121Insulin secretion_Homo sapiens_hsa049110.08316943
122Salivary secretion_Homo sapiens_hsa049700.07761210
123Tuberculosis_Homo sapiens_hsa051520.07075990
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.07062997
125Adherens junction_Homo sapiens_hsa045200.06738877
126Rheumatoid arthritis_Homo sapiens_hsa053230.06208914
127Phosphatidylinositol signaling system_Homo sapiens_hsa040700.06019963
128Selenocompound metabolism_Homo sapiens_hsa004500.05561213
129Aldosterone synthesis and secretion_Homo sapiens_hsa049250.05132542
130Hematopoietic cell lineage_Homo sapiens_hsa046400.03858813

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