MRPS36

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)9.59493313
2energy coupled proton transport, down electrochemical gradient (GO:0015985)9.11483146
3ATP synthesis coupled proton transport (GO:0015986)9.11483146
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)8.55906034
5respiratory electron transport chain (GO:0022904)7.86027786
6electron transport chain (GO:0022900)7.66885051
7mitochondrial respiratory chain complex I assembly (GO:0032981)5.92303455
8NADH dehydrogenase complex assembly (GO:0010257)5.92303455
9mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.92303455
10protein complex biogenesis (GO:0070271)5.72180890
11protein neddylation (GO:0045116)5.51334352
12chaperone-mediated protein transport (GO:0072321)5.33195574
13mitochondrial respiratory chain complex assembly (GO:0033108)5.25792757
14oxidative phosphorylation (GO:0006119)5.09980619
15ATP biosynthetic process (GO:0006754)4.86580849
16hydrogen ion transmembrane transport (GO:1902600)4.77419920
17establishment of protein localization to mitochondrial membrane (GO:0090151)4.73844362
18purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.70197566
19purine nucleoside triphosphate biosynthetic process (GO:0009145)4.62731961
20ribosomal small subunit biogenesis (GO:0042274)4.60726093
21proteasome assembly (GO:0043248)4.55374962
22viral transcription (GO:0019083)4.52727941
23translational termination (GO:0006415)4.32594347
24inner mitochondrial membrane organization (GO:0007007)4.32064283
25proton transport (GO:0015992)4.24582568
26cotranslational protein targeting to membrane (GO:0006613)4.20619885
27hydrogen transport (GO:0006818)4.14801215
28SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.14678675
29ribonucleoside triphosphate biosynthetic process (GO:0009201)4.14470903
30GTP biosynthetic process (GO:0006183)4.12856076
31protein targeting to ER (GO:0045047)4.12271401
32establishment of protein localization to endoplasmic reticulum (GO:0072599)3.95620390
33aerobic respiration (GO:0009060)3.94998937
34protein localization to endoplasmic reticulum (GO:0070972)3.94989433
35ribosomal small subunit assembly (GO:0000028)3.92902064
36cullin deneddylation (GO:0010388)3.90983627
37transcription elongation from RNA polymerase III promoter (GO:0006385)3.86053095
38termination of RNA polymerase III transcription (GO:0006386)3.86053095
39nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.84376520
40rRNA modification (GO:0000154)3.83316150
41exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.82998143
42regulation of mitochondrial translation (GO:0070129)3.79792211
43water-soluble vitamin biosynthetic process (GO:0042364)3.76735048
44protein targeting to mitochondrion (GO:0006626)3.76626529
45translational elongation (GO:0006414)3.72274168
46L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.71986690
47respiratory chain complex IV assembly (GO:0008535)3.71912092
48regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.68014169
49protein deneddylation (GO:0000338)3.66002598
50establishment of protein localization to mitochondrion (GO:0072655)3.64704551
51nucleoside triphosphate biosynthetic process (GO:0009142)3.64442892
52cytochrome complex assembly (GO:0017004)3.58267627
53quinone biosynthetic process (GO:1901663)3.56103240
54ubiquinone biosynthetic process (GO:0006744)3.56103240
55viral life cycle (GO:0019058)3.55211369
56cellular protein complex disassembly (GO:0043624)3.52323684
57regulation of cellular amino acid metabolic process (GO:0006521)3.51285291
58* translation (GO:0006412)3.49153257
59intracellular protein transmembrane import (GO:0044743)3.44765218
60protein localization to mitochondrion (GO:0070585)3.43936965
61tricarboxylic acid cycle (GO:0006099)3.43477669
62mitochondrial transport (GO:0006839)3.43344535
63UTP biosynthetic process (GO:0006228)3.43162016
64negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.42768365
65tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.41993074
66RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.41993074
67anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.39178557
68ubiquinone metabolic process (GO:0006743)3.37812323
69heart process (GO:0003015)3.36284799
70heart contraction (GO:0060047)3.36284799
71protein-cofactor linkage (GO:0018065)3.33588962
72guanosine-containing compound biosynthetic process (GO:1901070)3.33581749
73positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.29504416
74antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.28469882
75CENP-A containing nucleosome assembly (GO:0034080)3.25251418
76DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.23920022
77ribosomal large subunit biogenesis (GO:0042273)3.22240932
78chromatin remodeling at centromere (GO:0031055)3.22206179
79negative regulation of ligase activity (GO:0051352)3.21804384
80negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.21804384
81positive regulation of ligase activity (GO:0051351)3.17228546
82fatty acid elongation (GO:0030497)3.16339319
83signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.15559252
84intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.15559252
85rRNA methylation (GO:0031167)3.14919006
86pseudouridine synthesis (GO:0001522)3.14195582
87energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.11593997
88ATP hydrolysis coupled proton transport (GO:0015991)3.11593997
89antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.10906623
90signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.10577401
91signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.10577401
92signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.10577401
93translational initiation (GO:0006413)3.09798685
94cellular respiration (GO:0045333)3.06116644
95purine nucleoside monophosphate biosynthetic process (GO:0009127)3.05762083
96purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.05762083
977-methylguanosine RNA capping (GO:0009452)3.05106611
98RNA capping (GO:0036260)3.05106611
99maturation of SSU-rRNA (GO:0030490)3.04496850
100positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.03797698
101DNA double-strand break processing (GO:0000729)3.02799636
1027-methylguanosine mRNA capping (GO:0006370)3.02526377
103cellular component biogenesis (GO:0044085)3.00279295
104nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.99547470
105sequestering of actin monomers (GO:0042989)2.99170523
106signal transduction involved in DNA damage checkpoint (GO:0072422)2.98626019
107signal transduction involved in DNA integrity checkpoint (GO:0072401)2.98626019
108establishment of integrated proviral latency (GO:0075713)2.98174509
109UTP metabolic process (GO:0046051)2.97655293
110signal transduction involved in cell cycle checkpoint (GO:0072395)2.94747020
111DNA damage response, detection of DNA damage (GO:0042769)2.94248108
112regulation of cellular respiration (GO:0043457)2.92933645
113regulation of oxidative phosphorylation (GO:0002082)2.91999828
114platelet dense granule organization (GO:0060155)2.89991445
115iron-sulfur cluster assembly (GO:0016226)2.89146676
116metallo-sulfur cluster assembly (GO:0031163)2.89146676
117CTP biosynthetic process (GO:0006241)2.89071003
118CTP metabolic process (GO:0046036)2.89071003
119mitochondrion morphogenesis (GO:0070584)2.87808992
120regulation of ubiquitin-protein transferase activity (GO:0051438)2.86480895
121DNA deamination (GO:0045006)2.85213354
122spliceosomal snRNP assembly (GO:0000387)2.81897674
123protein targeting to membrane (GO:0006612)2.81883681
124organelle disassembly (GO:1903008)2.80724341
125regulation of ligase activity (GO:0051340)2.78051114
126rRNA processing (GO:0006364)2.76032625
127signal peptide processing (GO:0006465)2.71882415

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.23847767
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.05590422
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.57668448
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.19768809
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.97061179
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.89526138
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.79043949
8CREB1_15753290_ChIP-ChIP_HEK293T_Human3.56112253
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.41583623
10* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.32089129
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.31035598
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.25986691
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.17085487
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.95196358
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.94585921
16SRF_21415370_ChIP-Seq_HL-1_Mouse2.81900147
17PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.69329701
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.62846047
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.42192113
20VDR_23849224_ChIP-Seq_CD4+_Human2.28484268
21DCP1A_22483619_ChIP-Seq_HELA_Human2.26030184
22THAP11_20581084_ChIP-Seq_MESCs_Mouse2.19373110
23YY1_21170310_ChIP-Seq_MESCs_Mouse2.15453181
24CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.12944614
25ELK1_19687146_ChIP-ChIP_HELA_Human2.11470117
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.05713397
27* ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.04709248
28VDR_22108803_ChIP-Seq_LS180_Human1.97981561
29* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.96179563
30ZNF274_21170338_ChIP-Seq_K562_Hela1.95305973
31MYC_19030024_ChIP-ChIP_MESCs_Mouse1.93470963
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.78717494
33TTF2_22483619_ChIP-Seq_HELA_Human1.75229386
34ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.74338756
35* FOXP3_21729870_ChIP-Seq_TREG_Human1.73053310
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.66096048
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64505705
38MYC_19079543_ChIP-ChIP_MESCs_Mouse1.64488018
39* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63491567
40XRN2_22483619_ChIP-Seq_HELA_Human1.61879799
41ELK1_22589737_ChIP-Seq_MCF10A_Human1.60687001
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59804759
43GABP_19822575_ChIP-Seq_HepG2_Human1.43931716
44MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.35043995
45P300_19829295_ChIP-Seq_ESCs_Human1.31691464
46NELFA_20434984_ChIP-Seq_ESCs_Mouse1.31045394
47BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.30707664
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24184788
49* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.20742151
50CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.19996056
51TP53_22573176_ChIP-Seq_HFKS_Human1.19506433
52FUS_26573619_Chip-Seq_HEK293_Human1.18721554
53TAF15_26573619_Chip-Seq_HEK293_Human1.18660623
54CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16537921
55HTT_18923047_ChIP-ChIP_STHdh_Human1.16204235
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.15350931
57IRF1_19129219_ChIP-ChIP_H3396_Human1.15153189
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15059835
59ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14838141
60FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.14824219
61CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.13794646
62MYC_18940864_ChIP-ChIP_HL60_Human1.13151565
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11330540
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09329263
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.08874443
66YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08711534
67NANOG_19829295_ChIP-Seq_ESCs_Human1.07741424
68SOX2_19829295_ChIP-Seq_ESCs_Human1.07741424
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.07409621
70EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.04838844
71ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04584453
72NANOG_16153702_ChIP-ChIP_HESCs_Human1.02967269
73FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02876015
74FOXA1_25329375_ChIP-Seq_VCAP_Human1.02876015
75CTCF_18555785_ChIP-Seq_MESCs_Mouse1.02761360
76SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99007626
77PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98661266
78SOX2_16153702_ChIP-ChIP_HESCs_Human0.97463271
79EZH2_27294783_Chip-Seq_NPCs_Mouse0.97165418
80TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96684566
81NFE2_27457419_Chip-Seq_LIVER_Mouse0.95269186
82PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94529127
83ER_23166858_ChIP-Seq_MCF-7_Human0.93816911
84AR_20517297_ChIP-Seq_VCAP_Human0.93511588
85NOTCH1_21737748_ChIP-Seq_TLL_Human0.91804122
86EZH2_22144423_ChIP-Seq_EOC_Human0.90552424
87RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90513822
88PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90320882
89CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.89713223
90PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.88922586
91FLI1_27457419_Chip-Seq_LIVER_Mouse0.87796938
92UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.85782404
93CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85579219
94SALL1_21062744_ChIP-ChIP_HESCs_Human0.84162152
95EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.83511428
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.82405378
97POU3F2_20337985_ChIP-ChIP_501MEL_Human0.82133379
98ERG_20517297_ChIP-Seq_VCAP_Human0.81858382
99CBP_20019798_ChIP-Seq_JUKART_Human0.81779270
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.81779270
101* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.81774522
102STAT1_20625510_ChIP-Seq_HELA_Human0.81675928
103PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.81008465
104POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.80537134
105IGF1R_20145208_ChIP-Seq_DFB_Human0.79948022
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.78814622
107E2F4_17652178_ChIP-ChIP_JURKAT_Human0.77964973
108RBPJ_22232070_ChIP-Seq_NCS_Mouse0.77253170
109RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.75648861
110SRY_22984422_ChIP-ChIP_TESTIS_Rat0.73816096
111* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.72142772
112NANOG_20526341_ChIP-Seq_ESCs_Human0.72111807
113EWS_26573619_Chip-Seq_HEK293_Human0.72105754
114MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.72046176
115CBX2_27304074_Chip-Seq_ESCs_Mouse0.71112729
116LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.70220763
117NANOG_18555785_ChIP-Seq_MESCs_Mouse0.69245646
118GBX2_23144817_ChIP-Seq_PC3_Human0.68924572
119SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.68385300
120MYCN_18555785_ChIP-Seq_MESCs_Mouse0.67711163
121ZFX_18555785_ChIP-Seq_MESCs_Mouse0.67279259
122SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.66440551
123GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.65422706
124* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.65044429
125CTBP1_25329375_ChIP-Seq_LNCAP_Human0.64467082
126YY1_22570637_ChIP-Seq_MALME-3M_Human0.63952707
127ETV2_25802403_ChIP-Seq_MESCs_Mouse0.63138697
128SALL4_22934838_ChIP-ChIP_CD34+_Human0.63024905

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis4.01400120
2MP0003646_muscle_fatigue3.76710362
3MP0001529_abnormal_vocalization3.74137740
4MP0006036_abnormal_mitochondrial_physio3.16980780
5MP0009379_abnormal_foot_pigmentation2.98923595
6MP0004215_abnormal_myocardial_fiber2.79586210
7MP0000749_muscle_degeneration2.75059653
8MP0005084_abnormal_gallbladder_morpholo2.53113267
9MP0008058_abnormal_DNA_repair2.49509007
10MP0001905_abnormal_dopamine_level2.48005321
11MP0000751_myopathy2.44676551
12MP0003011_delayed_dark_adaptation2.43167857
13MP0003880_abnormal_central_pattern2.37553521
14MP0002102_abnormal_ear_morphology2.32971686
15MP0006035_abnormal_mitochondrial_morpho2.29885099
16MP0003136_yellow_coat_color2.28104899
17MP0004084_abnormal_cardiac_muscle2.22981926
18MP0004036_abnormal_muscle_relaxation2.20786063
19MP0004147_increased_porphyrin_level2.11784404
20MP0005330_cardiomyopathy2.04869852
21MP0003186_abnormal_redox_activity1.99000738
22MP0003950_abnormal_plasma_membrane1.96827077
23MP0002736_abnormal_nociception_after1.95292832
24MP0006276_abnormal_autonomic_nervous1.93049930
25MP0004142_abnormal_muscle_tone1.92650438
26MP0003137_abnormal_impulse_conducting1.86229248
27MP0003806_abnormal_nucleotide_metabolis1.79718363
28MP0002163_abnormal_gland_morphology1.72032214
29MP0001764_abnormal_homeostasis1.69216119
30MP0002638_abnormal_pupillary_reflex1.68329882
31MP0002972_abnormal_cardiac_muscle1.67055438
32MP0005253_abnormal_eye_physiology1.66419970
33MP0003195_calcinosis1.62595705
34MP0008875_abnormal_xenobiotic_pharmacok1.61860293
35MP0008775_abnormal_heart_ventricle1.53648256
36MP0005646_abnormal_pituitary_gland1.53583331
37MP0008995_early_reproductive_senescence1.53484617
38MP0001968_abnormal_touch/_nociception1.49965558
39MP0008877_abnormal_DNA_methylation1.49026636
40MP0004145_abnormal_muscle_electrophysio1.47189775
41MP0005171_absent_coat_pigmentation1.43816033
42MP0002332_abnormal_exercise_endurance1.43743207
43MP0003786_premature_aging1.43450493
44MP0009046_muscle_twitch1.42369109
45MP0000920_abnormal_myelination1.41947908
46MP0002272_abnormal_nervous_system1.41571459
47MP0008872_abnormal_physiological_respon1.40987195
48MP0003656_abnormal_erythrocyte_physiolo1.38739029
49MP0001485_abnormal_pinna_reflex1.38499702
50MP0000372_irregular_coat_pigmentation1.38098073
51MP0002106_abnormal_muscle_physiology1.37843365
52MP0005620_abnormal_muscle_contractility1.35727228
53MP0001727_abnormal_embryo_implantation1.32836262
54MP0003718_maternal_effect1.31672565
55MP0005408_hypopigmentation1.31666729
56MP0004484_altered_response_of1.30279336
57MP0005451_abnormal_body_composition1.29779080
58MP0002277_abnormal_respiratory_mucosa1.29302371
59MP0001986_abnormal_taste_sensitivity1.27133906
60MP0008789_abnormal_olfactory_epithelium1.25769122
61MP0010094_abnormal_chromosome_stability1.24811691
62MP0002735_abnormal_chemical_nociception1.24546647
63MP0002132_abnormal_respiratory_system1.24059688
64MP0005075_abnormal_melanosome_morpholog1.20010317
65MP0001984_abnormal_olfaction1.19155035
66MP0005332_abnormal_amino_acid1.18454553
67MP0001544_abnormal_cardiovascular_syste1.17050039
68MP0005385_cardiovascular_system_phenoty1.17050039
69MP0004043_abnormal_pH_regulation1.17024588
70MP0008932_abnormal_embryonic_tissue1.16921893
71MP0003941_abnormal_skin_development1.16062563
72MP0000631_abnormal_neuroendocrine_gland1.15614992
73MP0000750_abnormal_muscle_regeneration1.15428039
74MP0005174_abnormal_tail_pigmentation1.14262796
75MP0002064_seizures1.13890590
76MP0003693_abnormal_embryo_hatching1.13825950
77MP0005409_darkened_coat_color1.13740506
78MP0005369_muscle_phenotype1.12960876
79MP0005266_abnormal_metabolism1.11613488
80MP0004742_abnormal_vestibular_system1.11350339
81MP0004085_abnormal_heartbeat1.11117021
82MP0002095_abnormal_skin_pigmentation1.09954159
83MP0002148_abnormal_hypersensitivity_rea1.09424921
84MP0001293_anophthalmia1.06852038
85MP0009745_abnormal_behavioral_response1.02570810
86MP0002734_abnormal_mechanical_nocicepti1.02075329
87MP0003221_abnormal_cardiomyocyte_apopto1.01996119
88MP0003121_genomic_imprinting1.01661106
89MP0002751_abnormal_autonomic_nervous1.01055294
90MP0005085_abnormal_gallbladder_physiolo1.00565630
91MP0002234_abnormal_pharynx_morphology1.00003322
92MP0002090_abnormal_vision0.99558814
93MP0001970_abnormal_pain_threshold0.99126802
94MP0000569_abnormal_digit_pigmentation0.98911299
95MP0004087_abnormal_muscle_fiber0.98868272
96MP0004133_heterotaxia0.98218623
97MP0004924_abnormal_behavior0.96683758
98MP0005386_behavior/neurological_phenoty0.96683758
99MP0008057_abnormal_DNA_replication0.93134708
100MP0000747_muscle_weakness0.92882880
101MP0003567_abnormal_fetal_cardiomyocyte0.92287604
102MP0001440_abnormal_grooming_behavior0.92069639
103MP0005379_endocrine/exocrine_gland_phen0.91619196
104MP0002160_abnormal_reproductive_system0.91145815
105MP0008007_abnormal_cellular_replicative0.89627425
106MP0006138_congestive_heart_failure0.89180119
107MP0002127_abnormal_cardiovascular_syste0.88941112
108MP0004957_abnormal_blastocyst_morpholog0.87796824
109MP0000343_altered_response_to0.86306993
110MP0003724_increased_susceptibility_to0.85376697
111MP0002067_abnormal_sensory_capabilities0.84523266
112MP0010386_abnormal_urinary_bladder0.84323894
113MP0000759_abnormal_skeletal_muscle0.84250320
114MP0003122_maternal_imprinting0.84030177
115MP0001188_hyperpigmentation0.83939916
116MP0006072_abnormal_retinal_apoptosis0.83163463
117MP0005423_abnormal_somatic_nervous0.79718596
118MP0005389_reproductive_system_phenotype0.79013171
119MP0003077_abnormal_cell_cycle0.79012792
120MP0005645_abnormal_hypothalamus_physiol0.78681607
121MP0005410_abnormal_fertilization0.78347348
122MP0008260_abnormal_autophagy0.78239296
123MP0002572_abnormal_emotion/affect_behav0.78207842
124MP0000230_abnormal_systemic_arterial0.77981908
125MP0001486_abnormal_startle_reflex0.77171133
126MP0005165_increased_susceptibility_to0.77163750
127MP0005195_abnormal_posterior_eye0.75837259
128MP0004381_abnormal_hair_follicle0.75530245
129MP0002210_abnormal_sex_determination0.74441553
130MP0002876_abnormal_thyroid_physiology0.74148130
131MP0005551_abnormal_eye_electrophysiolog0.73364948
132MP0005636_abnormal_mineral_homeostasis0.73273420
133MP0002229_neurodegeneration0.73191665
134MP0009697_abnormal_copulation0.72793442
135MP0004019_abnormal_vitamin_homeostasis0.71311280
136MP0006292_abnormal_olfactory_placode0.71043577
137MP0002269_muscular_atrophy0.70678059
138MP0000026_abnormal_inner_ear0.68727069
139MP0005376_homeostasis/metabolism_phenot0.68189911
140MP0003828_pulmonary_edema0.67762727
141MP0002282_abnormal_trachea_morphology0.67613869
142MP0001963_abnormal_hearing_physiology0.67019157
143MP0002938_white_spotting0.66798761
144MP0000653_abnormal_sex_gland0.66566368
145MP0002752_abnormal_somatic_nervous0.65984933
146MP0003252_abnormal_bile_duct0.65100101
147MP0005391_vision/eye_phenotype0.64491400
148MP0010030_abnormal_orbit_morphology0.62623723
149MP0001929_abnormal_gametogenesis0.61774976
150MP0002928_abnormal_bile_duct0.61049425
151MP0003937_abnormal_limbs/digits/tail_de0.60232971

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)7.81672409
2Abnormal mitochondria in muscle tissue (HP:0008316)7.19799260
3Mitochondrial inheritance (HP:0001427)6.79954665
4Progressive macrocephaly (HP:0004481)6.48921364
5Acute encephalopathy (HP:0006846)6.36109092
6Hepatocellular necrosis (HP:0001404)6.03273948
7Increased CSF lactate (HP:0002490)5.87294428
8Hepatic necrosis (HP:0002605)5.48436516
9Increased hepatocellular lipid droplets (HP:0006565)5.11485355
10Lipid accumulation in hepatocytes (HP:0006561)4.68557962
11Abnormality of glycolysis (HP:0004366)4.63866317
12Increased serum pyruvate (HP:0003542)4.63866317
13Renal Fanconi syndrome (HP:0001994)4.39972273
14Cerebral edema (HP:0002181)4.39320279
15Increased intramyocellular lipid droplets (HP:0012240)4.33225885
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.32227092
17Exercise intolerance (HP:0003546)4.28463677
18Respiratory failure (HP:0002878)4.28264834
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.14280329
20Decreased activity of mitochondrial respiratory chain (HP:0008972)4.14280329
21Lactic acidosis (HP:0003128)4.02871398
22Optic disc pallor (HP:0000543)3.96793081
23Leukodystrophy (HP:0002415)3.88750806
24Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.88033164
25Increased serum lactate (HP:0002151)3.84571505
26Increased muscle lipid content (HP:0009058)3.82529701
27Exertional dyspnea (HP:0002875)3.66717605
28Abnormality of cells of the erythroid lineage (HP:0012130)3.52890947
293-Methylglutaconic aciduria (HP:0003535)3.42390182
30Abnormal number of erythroid precursors (HP:0012131)3.21193354
31Respiratory difficulties (HP:0002880)3.05528331
32Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.01106075
33Abnormality of renal resorption (HP:0011038)2.95762843
34Congenital, generalized hypertrichosis (HP:0004540)2.95371976
35Neuroendocrine neoplasm (HP:0100634)2.91640827
36Pheochromocytoma (HP:0002666)2.78785017
37CNS demyelination (HP:0007305)2.54557686
38Parakeratosis (HP:0001036)2.52249972
39Aplastic anemia (HP:0001915)2.50142981
40Muscle hypertrophy of the lower extremities (HP:0008968)2.49397435
41X-linked dominant inheritance (HP:0001423)2.48409207
42True hermaphroditism (HP:0010459)2.44279776
43Pancreatic cysts (HP:0001737)2.44078728
44Sudden death (HP:0001699)2.42176593
45Pancreatic fibrosis (HP:0100732)2.40445056
46Abnormality of methionine metabolism (HP:0010901)2.36941252
47Emotional lability (HP:0000712)2.35058394
48Abnormality of aspartate family amino acid metabolism (HP:0010899)2.34041306
49Calf muscle hypertrophy (HP:0008981)2.33036075
50Palpitations (HP:0001962)2.32974667
51Abnormality of urine glucose concentration (HP:0011016)2.32304172
52Glycosuria (HP:0003076)2.32304172
53Macrocytic anemia (HP:0001972)2.32208391
54Molar tooth sign on MRI (HP:0002419)2.29914261
55Abnormality of midbrain morphology (HP:0002418)2.29914261
56Abnormality of the anterior horn cell (HP:0006802)2.29290814
57Degeneration of anterior horn cells (HP:0002398)2.29290814
58Hyperphosphaturia (HP:0003109)2.16752929
59Reticulocytopenia (HP:0001896)2.15979922
60Hyperglycinemia (HP:0002154)2.13646016
61Abnormality of serum amino acid levels (HP:0003112)2.13166212
62Lethargy (HP:0001254)2.12040677
63Abnormality of vitamin B metabolism (HP:0004340)2.11316884
64Congenital ichthyosiform erythroderma (HP:0007431)2.09506874
65Conjunctival hamartoma (HP:0100780)2.04690258
66Abnormality of the vitamin B12 metabolism (HP:0004341)2.01400205
67Microvesicular hepatic steatosis (HP:0001414)2.00967795
68Stenosis of the external auditory canal (HP:0000402)1.98648329
69Reduced antithrombin III activity (HP:0001976)1.98302770
70Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.95780679
71Abnormality of alanine metabolism (HP:0010916)1.95780679
72Hyperalaninemia (HP:0003348)1.95780679
73Renal cortical cysts (HP:0000803)1.94537103
74Medial flaring of the eyebrow (HP:0010747)1.92747371
75Gliosis (HP:0002171)1.90440193
76Abnormal urine phosphate concentration (HP:0012599)1.90033265
77Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.89908064
78Abnormal protein N-linked glycosylation (HP:0012347)1.89908064
79Abnormal protein glycosylation (HP:0012346)1.89908064
80Abnormal glycosylation (HP:0012345)1.89908064
81Pallor (HP:0000980)1.87567074
82Blindness (HP:0000618)1.87262888
83Rhabdomyolysis (HP:0003201)1.86538284
84Sensory axonal neuropathy (HP:0003390)1.85591375
85Nephronophthisis (HP:0000090)1.85206139
86Aplasia/Hypoplasia of the sacrum (HP:0008517)1.83444550
87Renal tubular dysfunction (HP:0000124)1.82581037
88Ventricular tachycardia (HP:0004756)1.80366414
89Sclerocornea (HP:0000647)1.79183556
90Exercise-induced muscle cramps (HP:0003710)1.78684964
91Hypothermia (HP:0002045)1.78345749
92Aplasia/hypoplasia of the uterus (HP:0008684)1.77230613
93Cerebral hypomyelination (HP:0006808)1.77040616
94Lipoatrophy (HP:0100578)1.76861947
95Megaloblastic anemia (HP:0001889)1.75440955
96Hypoglycemic coma (HP:0001325)1.74821736
97Abnormality of the labia minora (HP:0012880)1.74343898
98Oral leukoplakia (HP:0002745)1.73361449
99Progressive external ophthalmoplegia (HP:0000590)1.72389369
100Hyperglycinuria (HP:0003108)1.71981510
101Methylmalonic aciduria (HP:0012120)1.71980112
102Type I transferrin isoform profile (HP:0003642)1.69243007
103Pancytopenia (HP:0001876)1.68685271
104Neoplasm of head and neck (HP:0012288)1.68210580
105Esophageal neoplasm (HP:0100751)1.68210580
106Abnormality of the heme biosynthetic pathway (HP:0010472)1.67368625
107Abnormality of dicarboxylic acid metabolism (HP:0010995)1.65907283
108Dicarboxylic aciduria (HP:0003215)1.65907283
109Hypoplastic left heart (HP:0004383)1.65227697
110Abnormality of placental membranes (HP:0011409)1.65154094
111Amniotic constriction ring (HP:0009775)1.65154094
112Male pseudohermaphroditism (HP:0000037)1.64207532
113Myoglobinuria (HP:0002913)1.63971286
114Vomiting (HP:0002013)1.63923557
115Abnormality of the calf musculature (HP:0001430)1.63482194
116Methylmalonic acidemia (HP:0002912)1.63073974
117Congenital stationary night blindness (HP:0007642)1.62334728
118Myotonia (HP:0002486)1.62300742
119Absent thumb (HP:0009777)1.62196087
120Muscle fiber splitting (HP:0003555)1.61063355
121Abnormality of glycine metabolism (HP:0010895)1.60809375
122Abnormality of serine family amino acid metabolism (HP:0010894)1.60809375
123Cerebral hemorrhage (HP:0001342)1.60453510
124Dilated cardiomyopathy (HP:0001644)1.60013027
125Abnormal pupillary function (HP:0007686)1.59719381
126Septo-optic dysplasia (HP:0100842)1.59266705
127Abnormal hair whorl (HP:0010721)1.57952758
128Exercise-induced myalgia (HP:0003738)1.57800731
129Generalized aminoaciduria (HP:0002909)1.57478926
130Genital tract atresia (HP:0001827)1.57203957
131Supraventricular tachycardia (HP:0004755)1.56986147
132Colon cancer (HP:0003003)1.56904570
133Atrial fibrillation (HP:0005110)1.56629590
134Retinal dysplasia (HP:0007973)1.55343023
135Congenital primary aphakia (HP:0007707)1.53499903
136Nephrogenic diabetes insipidus (HP:0009806)1.52352501
137Gait imbalance (HP:0002141)1.50707788
138Ragged-red muscle fibers (HP:0003200)1.49904374
139Supraventricular arrhythmia (HP:0005115)1.47642849

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME23.59666704
2STK163.24498098
3VRK23.13289475
4NME13.02090471
5PBK2.96032380
6MYLK2.85125455
7MST42.77279413
8STK392.46926735
9MAP3K122.28001437
10LIMK12.22954985
11MUSK2.20639133
12CASK2.19178905
13GRK72.18188600
14EIF2AK12.12799153
15NEK12.11036449
16VRK12.05811306
17OBSCN2.05452874
18MAP4K21.98622750
19TLK11.92304355
20BUB11.89906780
21NUAK11.88305775
22ARAF1.85779710
23TRIM281.84222382
24OXSR11.76401436
25PIM21.70456271
26WNK41.66118702
27PLK31.64514450
28CDK191.62665369
29EIF2AK31.54907128
30FRK1.50947310
31GRK11.45107005
32CDC71.43195502
33ERBB31.42700083
34MAPKAPK51.37412447
35GRK51.34125735
36MKNK21.26620009
37BCR1.23849285
38PDK41.23563136
39PDK31.23563136
40BMPR21.19697020
41ADRBK21.19062759
42BMPR1B1.17712486
43MAP3K41.17619145
44PHKG11.14443065
45PHKG21.14443065
46SRPK11.13256563
47STK241.12686912
48DYRK21.08347225
49TESK21.04214434
50ACVR1B1.03568543
51MAP2K71.03513495
52ZAK1.02329922
53TNIK1.00803635
54BRAF1.00353151
55WEE11.00276699
56CAMK2D0.98678796
57PNCK0.98496593
58ILK0.96114727
59CSNK1G20.96080540
60BCKDK0.95563144
61ABL20.95155623
62TTK0.92974008
63INSRR0.92650681
64TAF10.89624451
65PDK20.89545441
66UHMK10.87885710
67ADRBK10.84279157
68LMTK20.84208551
69PLK10.83724916
70CSNK1G10.82870596
71CAMK2B0.79300980
72MAPK150.78782632
73PLK20.75724588
74CAMK2A0.74411201
75PIK3CA0.74132250
76TESK10.72925404
77DAPK30.72304699
78PINK10.71316475
79TSSK60.70843612
80ROCK20.70496110
81PKN10.69272768
82PLK40.68351295
83PRKCG0.68287970
84AURKA0.65428816
85KDR0.63141314
86DYRK30.62554757
87CAMK2G0.61927508
88AURKB0.61633707
89CCNB10.60413384
90PRKCE0.60210425
91MAPK130.60136901
92IRAK40.59807704
93MKNK10.57650428
94MINK10.55507970
95PASK0.55432532
96CSNK2A10.55363481
97CSNK1A1L0.54960794
98PAK30.53971148
99PRPF4B0.53768774
100PRKACA0.52364224
101RPS6KA50.52252623
102YES10.51275717
103CDK80.50812726
104EIF2AK20.50430363
105BLK0.50252336
106PAK40.48717522
107MAP3K110.47989693
108CDK30.43529959
109TIE10.43459522
110TEC0.43386849
111PAK10.42085658
112CSNK2A20.41759971
113CDK140.41515526
114CSNK1G30.41504143
115TXK0.41072228
116IRAK30.40783883
117ROCK10.40599181
118IRAK20.39456366
119SCYL20.38258223
120BRSK20.37770057
121RPS6KC10.36938535
122RPS6KL10.36938535
123FGFR20.35387056
124PRKCQ0.35368431
125SYK0.34802382
126STK40.34380361
127STK30.34365515
128ATR0.33918707
129CDK180.33516531
130PRKACB0.33234951
131CSNK1A10.32525210
132STK38L0.32491971
133WNK30.32477788
134CDK11A0.32477340
135DAPK10.32189274
136LYN0.31788496
137RPS6KA60.31769255
138ERBB40.31740556
139PRKG10.31536982

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001906.32357850
2Parkinsons disease_Homo sapiens_hsa050125.45897988
3Ribosome_Homo sapiens_hsa030104.06295353
4Alzheimers disease_Homo sapiens_hsa050104.01455811
5Huntingtons disease_Homo sapiens_hsa050163.86345300
6Proteasome_Homo sapiens_hsa030503.73206123
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.41489811
8Cardiac muscle contraction_Homo sapiens_hsa042603.00184486
9RNA polymerase_Homo sapiens_hsa030202.72860548
10Protein export_Homo sapiens_hsa030602.71022333
11Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.50718365
12Fatty acid elongation_Homo sapiens_hsa000622.24536717
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.86333781
14Collecting duct acid secretion_Homo sapiens_hsa049661.78723296
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.61704085
16Pyrimidine metabolism_Homo sapiens_hsa002401.49312931
17DNA replication_Homo sapiens_hsa030301.49064806
18Mismatch repair_Homo sapiens_hsa034301.44880226
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.44811861
20Homologous recombination_Homo sapiens_hsa034401.30651479
21One carbon pool by folate_Homo sapiens_hsa006701.26286340
22Nucleotide excision repair_Homo sapiens_hsa034201.15868518
23Vibrio cholerae infection_Homo sapiens_hsa051101.14237599
24Propanoate metabolism_Homo sapiens_hsa006401.13041479
25Pyruvate metabolism_Homo sapiens_hsa006201.12751913
26Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10985172
27Spliceosome_Homo sapiens_hsa030401.05591890
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.02532544
29Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01222017
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.01060599
31Maturity onset diabetes of the young_Homo sapiens_hsa049501.00371905
32Basal transcription factors_Homo sapiens_hsa030220.99647483
33Steroid biosynthesis_Homo sapiens_hsa001000.96317209
34Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96147257
35Purine metabolism_Homo sapiens_hsa002300.92361292
36Sulfur metabolism_Homo sapiens_hsa009200.91975695
37Metabolic pathways_Homo sapiens_hsa011000.87866749
38Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.87775569
39Rheumatoid arthritis_Homo sapiens_hsa053230.87394089
40Carbon metabolism_Homo sapiens_hsa012000.87219716
41Chemical carcinogenesis_Homo sapiens_hsa052040.85410320
42SNARE interactions in vesicular transport_Homo sapiens_hsa041300.83339864
43Glutathione metabolism_Homo sapiens_hsa004800.82965851
44Pentose and glucuronate interconversions_Homo sapiens_hsa000400.82156452
45Caffeine metabolism_Homo sapiens_hsa002320.81959016
46Tryptophan metabolism_Homo sapiens_hsa003800.81637267
47Nitrogen metabolism_Homo sapiens_hsa009100.80421606
48Primary bile acid biosynthesis_Homo sapiens_hsa001200.74900184
49Base excision repair_Homo sapiens_hsa034100.73895996
50Arachidonic acid metabolism_Homo sapiens_hsa005900.71702179
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71295317
52Ether lipid metabolism_Homo sapiens_hsa005650.70978820
53RNA degradation_Homo sapiens_hsa030180.70534693
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68330002
55Retinol metabolism_Homo sapiens_hsa008300.65224296
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.63228054
57Non-homologous end-joining_Homo sapiens_hsa034500.62164577
58Vitamin digestion and absorption_Homo sapiens_hsa049770.60040186
59Selenocompound metabolism_Homo sapiens_hsa004500.58504382
60Phagosome_Homo sapiens_hsa041450.55420325
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55145392
62Graft-versus-host disease_Homo sapiens_hsa053320.51335304
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.50878886
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.49525008
65Drug metabolism - other enzymes_Homo sapiens_hsa009830.49434058
66Vitamin B6 metabolism_Homo sapiens_hsa007500.48673558
67Linoleic acid metabolism_Homo sapiens_hsa005910.47135554
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.46572852
69Fatty acid metabolism_Homo sapiens_hsa012120.45712022
70RNA transport_Homo sapiens_hsa030130.44724525
71Serotonergic synapse_Homo sapiens_hsa047260.43590220
72Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.42895555
73Fanconi anemia pathway_Homo sapiens_hsa034600.42217219
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42043444
75Butanoate metabolism_Homo sapiens_hsa006500.42026179
76Folate biosynthesis_Homo sapiens_hsa007900.41992347
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41724735
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.41580220
79Arginine and proline metabolism_Homo sapiens_hsa003300.41355514
80Autoimmune thyroid disease_Homo sapiens_hsa053200.40024613
81Synaptic vesicle cycle_Homo sapiens_hsa047210.38856104
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37660636
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36816158
84Cysteine and methionine metabolism_Homo sapiens_hsa002700.36150263
85Sphingolipid metabolism_Homo sapiens_hsa006000.36059638
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.35968939
87Tyrosine metabolism_Homo sapiens_hsa003500.35408596
88Regulation of autophagy_Homo sapiens_hsa041400.35172137
89Allograft rejection_Homo sapiens_hsa053300.34913332
90Peroxisome_Homo sapiens_hsa041460.34192436
91Phenylalanine metabolism_Homo sapiens_hsa003600.34011156
92Fat digestion and absorption_Homo sapiens_hsa049750.33514950
93Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.33029649
94Dilated cardiomyopathy_Homo sapiens_hsa054140.32244593
95Sulfur relay system_Homo sapiens_hsa041220.31821662
96Asthma_Homo sapiens_hsa053100.31816776
97Oocyte meiosis_Homo sapiens_hsa041140.29729906
98Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29495862
99Cell cycle_Homo sapiens_hsa041100.28276897
100Phototransduction_Homo sapiens_hsa047440.28246047
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27691228
102Epstein-Barr virus infection_Homo sapiens_hsa051690.25353908
103Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.24809851
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.23593797
105Nicotine addiction_Homo sapiens_hsa050330.23432463
106Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.22888616
107N-Glycan biosynthesis_Homo sapiens_hsa005100.21727734
108Olfactory transduction_Homo sapiens_hsa047400.21614469
109Pentose phosphate pathway_Homo sapiens_hsa000300.21261176
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.18993046
111Biosynthesis of amino acids_Homo sapiens_hsa012300.18601889
112Fatty acid degradation_Homo sapiens_hsa000710.18271581
113Taste transduction_Homo sapiens_hsa047420.17986273
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.17974111
115Type I diabetes mellitus_Homo sapiens_hsa049400.16072080
116GABAergic synapse_Homo sapiens_hsa047270.09746089
117Morphine addiction_Homo sapiens_hsa050320.07720290
118beta-Alanine metabolism_Homo sapiens_hsa004100.06355155
119Fructose and mannose metabolism_Homo sapiens_hsa000510.06037369
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.05186678
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.04709231
122Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.04151614
123Systemic lupus erythematosus_Homo sapiens_hsa053220.03762470
124Calcium signaling pathway_Homo sapiens_hsa040200.02127542
125Hematopoietic cell lineage_Homo sapiens_hsa046400.01699295
126Mineral absorption_Homo sapiens_hsa049780.01514322

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