MRPS18B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.48796279
2chaperone-mediated protein transport (GO:0072321)5.25217305
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.16927344
4ATP synthesis coupled proton transport (GO:0015986)5.16927344
5DNA deamination (GO:0045006)4.99927305
6nucleobase biosynthetic process (GO:0046112)4.86702239
7proteasome assembly (GO:0043248)4.84902591
8purine nucleobase biosynthetic process (GO:0009113)4.83075183
9ribosome assembly (GO:0042255)4.65221146
10formation of translation preinitiation complex (GO:0001731)4.61083864
11maturation of SSU-rRNA (GO:0030490)4.42274508
12respiratory electron transport chain (GO:0022904)4.31540889
13mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.30153125
14ribosome biogenesis (GO:0042254)4.26769487
15rRNA modification (GO:0000154)4.25914237
16electron transport chain (GO:0022900)4.23127234
17protein complex biogenesis (GO:0070271)4.20122961
18oxidative phosphorylation (GO:0006119)4.16493092
19DNA replication checkpoint (GO:0000076)4.15172217
20DNA strand elongation involved in DNA replication (GO:0006271)4.11319033
21folic acid metabolic process (GO:0046655)4.08996058
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.06432999
23NADH dehydrogenase complex assembly (GO:0010257)4.06432999
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.06432999
25mitochondrial respiratory chain complex assembly (GO:0033108)4.06350010
26negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.03866112
27telomere maintenance via semi-conservative replication (GO:0032201)3.98049077
28DNA replication initiation (GO:0006270)3.97970212
29DNA strand elongation (GO:0022616)3.92656961
30positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.91981300
31ribonucleoprotein complex biogenesis (GO:0022613)3.89350090
32anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.87616495
33regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.87540530
34transcription elongation from RNA polymerase III promoter (GO:0006385)3.84071132
35termination of RNA polymerase III transcription (GO:0006386)3.84071132
36ribosomal large subunit biogenesis (GO:0042273)3.79247479
37ribosomal small subunit assembly (GO:0000028)3.78393424
38protein targeting to mitochondrion (GO:0006626)3.73649613
39GDP-mannose metabolic process (GO:0019673)3.69696450
40regulation of cellular amino acid metabolic process (GO:0006521)3.66149934
41negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.64556844
42negative regulation of ligase activity (GO:0051352)3.64556844
43pseudouridine synthesis (GO:0001522)3.63349154
44mitotic metaphase plate congression (GO:0007080)3.63226725
45rRNA processing (GO:0006364)3.60957271
46respiratory chain complex IV assembly (GO:0008535)3.58541650
47spliceosomal snRNP assembly (GO:0000387)3.55687018
48IMP biosynthetic process (GO:0006188)3.55248644
49establishment of integrated proviral latency (GO:0075713)3.54753604
50telomere maintenance via recombination (GO:0000722)3.54236612
51exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.54040426
52DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.51676580
537-methylguanosine mRNA capping (GO:0006370)3.51621285
54nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.51150621
55RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.49041334
56tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.49041334
57signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.48130178
58signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.48130178
59signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.48130178
60rRNA metabolic process (GO:0016072)3.48080650
61intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.46707891
62signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.46707891
63cytochrome complex assembly (GO:0017004)3.46536589
64positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.46310951
65signal transduction involved in DNA damage checkpoint (GO:0072422)3.43291237
66signal transduction involved in DNA integrity checkpoint (GO:0072401)3.43291237
67RNA capping (GO:0036260)3.42548636
687-methylguanosine RNA capping (GO:0009452)3.42548636
69establishment of protein localization to mitochondrion (GO:0072655)3.41661657
70termination of RNA polymerase I transcription (GO:0006363)3.38456309
71L-methionine salvage (GO:0071267)3.37085988
72L-methionine biosynthetic process (GO:0071265)3.37085988
73amino acid salvage (GO:0043102)3.37085988
74signal transduction involved in cell cycle checkpoint (GO:0072395)3.37015978
75regulation of mitochondrial translation (GO:0070129)3.36842536
76folic acid-containing compound biosynthetic process (GO:0009396)3.36719752
77rRNA methylation (GO:0031167)3.35286278
78protein localization to mitochondrion (GO:0070585)3.35071562
79transcription from RNA polymerase I promoter (GO:0006360)3.34690114
80L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.34252571
81deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.33083803
82positive regulation of ligase activity (GO:0051351)3.30624768
83aerobic respiration (GO:0009060)3.29991545
84transcription elongation from RNA polymerase I promoter (GO:0006362)3.29897482
85ribosomal small subunit biogenesis (GO:0042274)3.29001995
86regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.28587909
87cullin deneddylation (GO:0010388)3.26717512
88antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.26183782
89CENP-A containing nucleosome assembly (GO:0034080)3.25873240
90transcription-coupled nucleotide-excision repair (GO:0006283)3.24669250
91cellular component biogenesis (GO:0044085)3.23807248
92cell cycle G1/S phase transition (GO:0044843)3.23575074
93G1/S transition of mitotic cell cycle (GO:0000082)3.23575074
94mitotic recombination (GO:0006312)3.22079207
95translational initiation (GO:0006413)3.21432282
96cotranslational protein targeting to membrane (GO:0006613)3.20873213
97chromatin remodeling at centromere (GO:0031055)3.17460851
98ATP biosynthetic process (GO:0006754)3.17385895
99telomere maintenance via telomere lengthening (GO:0010833)3.17311308
100protein targeting to ER (GO:0045047)3.16833516
101pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.15749492
102peptidyl-histidine modification (GO:0018202)3.15729807
103translational termination (GO:0006415)3.15356800
104viral transcription (GO:0019083)3.14517622
105protein deneddylation (GO:0000338)3.14390903
106* translation (GO:0006412)3.14296932
107IMP metabolic process (GO:0046040)3.12538934
108protein localization to endoplasmic reticulum (GO:0070972)3.06836753
109antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.06636144
110mitotic nuclear envelope disassembly (GO:0007077)3.05207571
111regulation of ubiquitin-protein transferase activity (GO:0051438)3.04998368
112purine nucleoside triphosphate biosynthetic process (GO:0009145)3.04062880
113tRNA aminoacylation for protein translation (GO:0006418)3.03823477
114establishment of protein localization to endoplasmic reticulum (GO:0072599)3.03778758
115establishment of protein localization to mitochondrial membrane (GO:0090151)3.03380005
116protein localization to kinetochore (GO:0034501)3.02371087
117translational elongation (GO:0006414)3.00673664
118maturation of 5.8S rRNA (GO:0000460)3.00379420
119purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.00145243
120amino acid activation (GO:0043038)2.98251297
121tRNA aminoacylation (GO:0043039)2.98251297
122glycine metabolic process (GO:0006544)2.98094737
123nucleoside transmembrane transport (GO:1901642)2.98016951
124deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.97030336
125transcription initiation from RNA polymerase I promoter (GO:0006361)2.96221021
126tricarboxylic acid cycle (GO:0006099)2.96117106
127purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.95295048
128purine nucleoside monophosphate biosynthetic process (GO:0009127)2.95295048
129metaphase plate congression (GO:0051310)2.95258193
130protein-cofactor linkage (GO:0018065)2.94127315
131methionine biosynthetic process (GO:0009086)2.93870446
132viral mRNA export from host cell nucleus (GO:0046784)2.93816094
133regulation of ligase activity (GO:0051340)2.93628618
134DNA replication-dependent nucleosome assembly (GO:0006335)2.93179855
135DNA replication-dependent nucleosome organization (GO:0034723)2.93179855
136SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.91127246
137folic acid transport (GO:0015884)2.89878119
138nucleobase-containing small molecule interconversion (GO:0015949)2.88844620
139nucleotide-excision repair, DNA gap filling (GO:0006297)2.87353597
140positive regulation of cell cycle arrest (GO:0071158)2.86111658
141spliceosomal complex assembly (GO:0000245)2.85712955
142DNA replication-independent nucleosome assembly (GO:0006336)2.85692366
143DNA replication-independent nucleosome organization (GO:0034724)2.85692366

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.96113438
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.30480341
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.95519983
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.81951311
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.63716924
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.49275887
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.46734058
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.33618698
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.09300563
10* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.07907892
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.96365942
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.91822479
13* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.90974883
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.88888832
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.70160870
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.57885110
17VDR_23849224_ChIP-Seq_CD4+_Human2.41415454
18* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.41057491
19* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.32676065
20* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.29430505
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.28545910
22* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.25191938
23DCP1A_22483619_ChIP-Seq_HELA_Human2.23895753
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.20215905
25* XRN2_22483619_ChIP-Seq_HELA_Human2.20196294
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.18881618
27GABP_19822575_ChIP-Seq_HepG2_Human2.08871115
28FOXP3_21729870_ChIP-Seq_TREG_Human2.04330512
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.03750981
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.01320020
31YY1_21170310_ChIP-Seq_MESCs_Mouse1.97795135
32CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.95418720
33SRF_21415370_ChIP-Seq_HL-1_Mouse1.92038226
34* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.85320513
35NANOG_18555785_ChIP-Seq_MESCs_Mouse1.84794189
36* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.81910233
37AR_21909140_ChIP-Seq_LNCAP_Human1.80192137
38* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78469350
39SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75466944
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.72444661
41TTF2_22483619_ChIP-Seq_HELA_Human1.71757718
42* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70752604
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68974623
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.63827630
45* ELK1_19687146_ChIP-ChIP_HELA_Human1.58082451
46* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56162134
47* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50070754
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48089617
49E2F1_21310950_ChIP-Seq_MCF-7_Human1.45864467
50STAT3_1855785_ChIP-Seq_MESCs_Mouse1.45526573
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41852094
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41825755
53KDM5A_27292631_Chip-Seq_BREAST_Human1.41210822
54CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.41136372
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.40465724
56FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37633626
57POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.36626007
58CIITA_25753668_ChIP-Seq_RAJI_Human1.33293023
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30338673
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26283054
61ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24416361
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23088117
63* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.21537276
64MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19777353
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.17551378
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15547991
67KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.14812550
68TFEB_21752829_ChIP-Seq_HELA_Human1.14426307
69* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14303783
70PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13826037
71* ELK1_22589737_ChIP-Seq_MCF10A_Human1.12932203
72* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11130078
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07029528
74SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.06531082
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01968993
76CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.00072189
77HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.98838983
78* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97218414
79ZNF263_19887448_ChIP-Seq_K562_Human0.95151789
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94965310
81* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.93636580
82ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.93480299
83FOXP1_21924763_ChIP-Seq_HESCs_Human0.93430014
84CTCF_18555785_ChIP-Seq_MESCs_Mouse0.92245782
85SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91747880
86SRY_22984422_ChIP-ChIP_TESTIS_Rat0.88325951
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88322773
88HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88255672
89CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.88116999
90* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.87781834
91ESR1_15608294_ChIP-ChIP_MCF-7_Human0.86594743
92* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86368129
93* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.85537553
94FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.84869456
95MYC_18940864_ChIP-ChIP_HL60_Human0.84630327
96MYC_22102868_ChIP-Seq_BL_Human0.83786690
97* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.83365441
98NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.82292117
99* SPI1_23547873_ChIP-Seq_NB4_Human0.82204613
100NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.81258828
101PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.81150103
102SOX2_18555785_ChIP-Seq_MESCs_Mouse0.80538682
103NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.78779889
104PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.78092944
105GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77291150
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.77060392
107TBX5_21415370_ChIP-Seq_HL-1_Mouse0.76363358
108CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.75495017
109TCF3_18692474_ChIP-Seq_MEFs_Mouse0.75369791
110SOX17_20123909_ChIP-Seq_XEN_Mouse0.73346478
111YY1_22570637_ChIP-Seq_MALME-3M_Human0.73290363
112IRF1_19129219_ChIP-ChIP_H3396_Human0.70898490
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69861996
114TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.69661733

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.07715365
2MP0004957_abnormal_blastocyst_morpholog4.47998879
3MP0003111_abnormal_nucleus_morphology4.41233303
4MP0003806_abnormal_nucleotide_metabolis4.33658639
5MP0010094_abnormal_chromosome_stability4.06277601
6MP0003077_abnormal_cell_cycle3.61456506
7MP0008058_abnormal_DNA_repair3.41444866
8MP0008057_abnormal_DNA_replication3.29998303
9MP0000372_irregular_coat_pigmentation3.09771808
10MP0003718_maternal_effect2.69749666
11MP0008932_abnormal_embryonic_tissue2.56715725
12MP0008007_abnormal_cellular_replicative2.55339216
13MP0003186_abnormal_redox_activity2.38534410
14MP0003786_premature_aging2.38174586
15MP0002396_abnormal_hematopoietic_system2.10316670
16MP0001730_embryonic_growth_arrest2.08187077
17MP0006036_abnormal_mitochondrial_physio2.02708672
18MP0009840_abnormal_foam_cell1.95662360
19MP0002837_dystrophic_cardiac_calcinosis1.87688783
20MP0008995_early_reproductive_senescence1.84150647
21MP0001529_abnormal_vocalization1.79043063
22MP0000350_abnormal_cell_proliferation1.74444564
23MP0006035_abnormal_mitochondrial_morpho1.74053524
24MP0009333_abnormal_splenocyte_physiolog1.72418262
25MP0001764_abnormal_homeostasis1.68486795
26MP0008260_abnormal_autophagy1.64151224
27MP0004145_abnormal_muscle_electrophysio1.61242795
28MP0003123_paternal_imprinting1.61037875
29MP0000490_abnormal_crypts_of1.51597495
30MP0005408_hypopigmentation1.48436117
31MP0000358_abnormal_cell_content/1.45132238
32MP0002163_abnormal_gland_morphology1.44347153
33MP0009379_abnormal_foot_pigmentation1.43967690
34MP0005380_embryogenesis_phenotype1.43555797
35MP0001672_abnormal_embryogenesis/_devel1.43555797
36MP0006072_abnormal_retinal_apoptosis1.42078439
37MP0010307_abnormal_tumor_latency1.41201750
38MP0010352_gastrointestinal_tract_polyps1.40101041
39MP0000749_muscle_degeneration1.39937378
40MP0001697_abnormal_embryo_size1.39460993
41MP0002938_white_spotting1.39297622
42MP0002080_prenatal_lethality1.37751879
43MP0006292_abnormal_olfactory_placode1.36113562
44MP0000751_myopathy1.32098352
45MP0000313_abnormal_cell_death1.31661533
46MP0002139_abnormal_hepatobiliary_system1.30485615
47MP0003984_embryonic_growth_retardation1.29270404
48MP0002019_abnormal_tumor_incidence1.29081491
49MP0008877_abnormal_DNA_methylation1.26813250
50MP0002132_abnormal_respiratory_system1.26630624
51MP0002088_abnormal_embryonic_growth/wei1.25404891
52MP0005330_cardiomyopathy1.23583043
53MP0003656_abnormal_erythrocyte_physiolo1.22293557
54MP0001853_heart_inflammation1.22110103
55MP0002234_abnormal_pharynx_morphology1.21447277
56MP0005332_abnormal_amino_acid1.20215199
57MP0005075_abnormal_melanosome_morpholog1.19604958
58MP0001545_abnormal_hematopoietic_system1.18307585
59MP0005397_hematopoietic_system_phenotyp1.18307585
60MP0005085_abnormal_gallbladder_physiolo1.13500458
61MP0008789_abnormal_olfactory_epithelium1.11590718
62MP0009697_abnormal_copulation1.10793146
63MP0003315_abnormal_perineum_morphology1.10612615
64MP0005379_endocrine/exocrine_gland_phen1.08731952
65MP0005266_abnormal_metabolism1.05814192
66MP0002210_abnormal_sex_determination1.05410208
67MP0005360_urolithiasis1.04619783
68MP0003567_abnormal_fetal_cardiomyocyte1.04439096
69MP0005645_abnormal_hypothalamus_physiol1.03759541
70MP0005319_abnormal_enzyme/_coenzyme1.02247800
71MP0005365_abnormal_bile_salt1.01489141
72MP0001145_abnormal_male_reproductive1.00634158
73MP0000678_abnormal_parathyroid_gland0.99382169
74MP0002638_abnormal_pupillary_reflex0.99340494
75MP0005389_reproductive_system_phenotype0.98754252
76MP0002160_abnormal_reproductive_system0.98520545
77MP0005410_abnormal_fertilization0.97311695
78MP0001542_abnormal_bone_strength0.96165473
79MP0003221_abnormal_cardiomyocyte_apopto0.95903448
80MP0002086_abnormal_extraembryonic_tissu0.95740391
81MP0008872_abnormal_physiological_respon0.95714030
82MP0003011_delayed_dark_adaptation0.95610378
83MP0002085_abnormal_embryonic_tissue0.94539842
84MP0004019_abnormal_vitamin_homeostasis0.91937837
85MP0008775_abnormal_heart_ventricle0.91823158
86MP0001881_abnormal_mammary_gland0.91792618
87MP0005395_other_phenotype0.91418443
88MP0001905_abnormal_dopamine_level0.89663205
89MP0000747_muscle_weakness0.89540755
90MP0003646_muscle_fatigue0.89456253
91MP0001929_abnormal_gametogenesis0.87675851
92MP0000689_abnormal_spleen_morphology0.86827181
93MP0002095_abnormal_skin_pigmentation0.85746323
94MP0004147_increased_porphyrin_level0.84650195
95MP0002722_abnormal_immune_system0.84567517
96MP0001661_extended_life_span0.83917911
97MP0002102_abnormal_ear_morphology0.83285635
98MP0000653_abnormal_sex_gland0.83113239
99MP0000598_abnormal_liver_morphology0.82028557
100MP0002106_abnormal_muscle_physiology0.80471642
101MP0005384_cellular_phenotype0.80266075
102MP0003698_abnormal_male_reproductive0.80263822
103MP0005376_homeostasis/metabolism_phenot0.78062449
104MP0002269_muscular_atrophy0.76605816
105MP0001727_abnormal_embryo_implantation0.75147064
106MP0004197_abnormal_fetal_growth/weight/0.75084955
107MP0004215_abnormal_myocardial_fiber0.75077074
108MP0005646_abnormal_pituitary_gland0.74801333
109MP0000750_abnormal_muscle_regeneration0.74704633
110MP0003763_abnormal_thymus_physiology0.73218709
111MP0001119_abnormal_female_reproductive0.73155390
112MP0005451_abnormal_body_composition0.72633210
113MP0000609_abnormal_liver_physiology0.72122659
114MP0000858_altered_metastatic_potential0.71960930
115MP0008875_abnormal_xenobiotic_pharmacok0.70093163
116MP0002429_abnormal_blood_cell0.69515533
117MP0002084_abnormal_developmental_patter0.69421992
118MP0002398_abnormal_bone_marrow0.69406443
119MP0005253_abnormal_eye_physiology0.69405601
120MP0001919_abnormal_reproductive_system0.68254733
121MP0003195_calcinosis0.67963646
122MP0005083_abnormal_biliary_tract0.67409553
123MP0002090_abnormal_vision0.67103759
124MP0004233_abnormal_muscle_weight0.66442334
125MP0005621_abnormal_cell_physiology0.66007944
126MP0005670_abnormal_white_adipose0.65688366
127MP0008469_abnormal_protein_level0.64874864
128MP0003137_abnormal_impulse_conducting0.64511114
129MP0005551_abnormal_eye_electrophysiolog0.64433195
130MP0004808_abnormal_hematopoietic_stem0.63173429
131MP0005636_abnormal_mineral_homeostasis0.62941921
132MP0000015_abnormal_ear_pigmentation0.62781083
133MP0003890_abnormal_embryonic-extraembry0.61872410
134MP0009643_abnormal_urine_homeostasis0.61773792
135MP0000703_abnormal_thymus_morphology0.61361769
136MP0001756_abnormal_urination0.61176478
137MP0004133_heterotaxia0.61054571
138MP0001293_anophthalmia0.60452588
139MP0002161_abnormal_fertility/fecundity0.60120570
140MP0002736_abnormal_nociception_after0.60009404
141MP0009672_abnormal_birth_weight0.59457670
142MP0009785_altered_susceptibility_to0.58424325
143MP0005584_abnormal_enzyme/coenzyme_acti0.58344736

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.14571128
2Progressive macrocephaly (HP:0004481)4.36648918
3Breast hypoplasia (HP:0003187)4.26889102
4Abnormality of cells of the erythroid lineage (HP:0012130)3.91655636
5Abnormal number of erythroid precursors (HP:0012131)3.88751727
6Increased intramyocellular lipid droplets (HP:0012240)3.76615734
7Rough bone trabeculation (HP:0100670)3.76339805
8Cerebral hypomyelination (HP:0006808)3.70683414
9Reticulocytopenia (HP:0001896)3.57197022
10Oral leukoplakia (HP:0002745)3.53526203
11Carpal bone hypoplasia (HP:0001498)3.46870833
12Renal Fanconi syndrome (HP:0001994)3.43500655
13Increased muscle lipid content (HP:0009058)3.26687861
14Multiple enchondromatosis (HP:0005701)3.25616989
15Degeneration of anterior horn cells (HP:0002398)3.17545916
16Abnormality of the anterior horn cell (HP:0006802)3.17545916
17Increased serum lactate (HP:0002151)3.11250629
18Hyperglycinemia (HP:0002154)3.09409770
193-Methylglutaconic aciduria (HP:0003535)3.03842527
20Decreased activity of mitochondrial respiratory chain (HP:0008972)3.02828226
21Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.02828226
22Microvesicular hepatic steatosis (HP:0001414)3.02466018
23Hepatic necrosis (HP:0002605)3.02380168
24Macrocytic anemia (HP:0001972)2.98103478
25Abnormality of alanine metabolism (HP:0010916)2.96376804
26Hyperalaninemia (HP:0003348)2.96376804
27Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.96376804
28Hepatocellular necrosis (HP:0001404)2.94593053
29Aplastic anemia (HP:0001915)2.93823396
30Secondary amenorrhea (HP:0000869)2.89690228
31Premature ovarian failure (HP:0008209)2.88479838
32Increased CSF lactate (HP:0002490)2.81710992
33Progressive muscle weakness (HP:0003323)2.81439155
34Abnormality of pyrimidine metabolism (HP:0004353)2.79239931
35Megaloblastic anemia (HP:0001889)2.78195038
36Methylmalonic acidemia (HP:0002912)2.76881612
37Hyperglycinuria (HP:0003108)2.73921344
38Abnormality of glycolysis (HP:0004366)2.73828133
39Increased serum pyruvate (HP:0003542)2.73828133
40Methylmalonic aciduria (HP:0012120)2.72698251
41Ragged-red muscle fibers (HP:0003200)2.72248401
42Microretrognathia (HP:0000308)2.72057250
43Abnormal trabecular bone morphology (HP:0100671)2.67660886
44Acute necrotizing encephalopathy (HP:0006965)2.65583156
45Type I transferrin isoform profile (HP:0003642)2.65007854
46Patellar aplasia (HP:0006443)2.63406777
47Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.63022475
48Mitochondrial inheritance (HP:0001427)2.62743179
49Abnormality of serum amino acid levels (HP:0003112)2.60093818
50Trismus (HP:0000211)2.58827612
51Emotional lability (HP:0000712)2.58604833
52Impulsivity (HP:0100710)2.55882522
53CNS demyelination (HP:0007305)2.53685070
54Aplasia/Hypoplasia of the patella (HP:0006498)2.50706872
55Respiratory difficulties (HP:0002880)2.50186290
56Abnormal mitochondria in muscle tissue (HP:0008316)2.49910842
57Abnormality of methionine metabolism (HP:0010901)2.45909633
58Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.41703174
59Ureteral duplication (HP:0000073)2.41604902
60Acute encephalopathy (HP:0006846)2.40810649
61Lactic acidosis (HP:0003128)2.40702375
62Bone marrow hypocellularity (HP:0005528)2.40473403
63Generalized aminoaciduria (HP:0002909)2.40448912
64Abnormality of glycine metabolism (HP:0010895)2.39992910
65Abnormality of serine family amino acid metabolism (HP:0010894)2.39992910
66Abnormality of the preputium (HP:0100587)2.39070848
67Pallor (HP:0000980)2.38376488
68Premature graying of hair (HP:0002216)2.38187035
69Abnormality of chromosome stability (HP:0003220)2.37936835
70Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.36184070
71Optic disc pallor (HP:0000543)2.34796168
72Increased hepatocellular lipid droplets (HP:0006565)2.34758321
73Pancytopenia (HP:0001876)2.34651226
74Selective tooth agenesis (HP:0001592)2.32755637
75Nausea (HP:0002018)2.32500480
76Leukodystrophy (HP:0002415)2.31536076
77Abnormal spermatogenesis (HP:0008669)2.29594075
78Lethargy (HP:0001254)2.29054856
79Sparse eyelashes (HP:0000653)2.28935966
80Meckel diverticulum (HP:0002245)2.28584751
81CNS hypomyelination (HP:0003429)2.28316863
82Lipid accumulation in hepatocytes (HP:0006561)2.28276264
83Rhabdomyolysis (HP:0003201)2.28004425
84Chromsome breakage (HP:0040012)2.27566141
85Absent thumb (HP:0009777)2.26575249
86Abnormality of the umbilical cord (HP:0010881)2.22192308
87Chromosomal breakage induced by crosslinking agents (HP:0003221)2.21668568
88Cerebral edema (HP:0002181)2.20881949
89Reduced antithrombin III activity (HP:0001976)2.20546086
90Cellular immunodeficiency (HP:0005374)2.18974287
91Poor head control (HP:0002421)2.18076391
92Abnormality of the heme biosynthetic pathway (HP:0010472)2.15256180
93Abnormality of the ileum (HP:0001549)2.15139480
94Abnormal gallbladder physiology (HP:0012438)2.13612839
95Cholecystitis (HP:0001082)2.13612839
96Absent radius (HP:0003974)2.12061832
97Death in infancy (HP:0001522)2.11888232
98Colon cancer (HP:0003003)2.10534016
99Dicarboxylic aciduria (HP:0003215)2.08798826
100Abnormality of dicarboxylic acid metabolism (HP:0010995)2.08798826
101Prolonged neonatal jaundice (HP:0006579)2.07859051
102Nemaline bodies (HP:0003798)2.06692137
103Abnormality of urine glucose concentration (HP:0011016)2.05071116
104Glycosuria (HP:0003076)2.05071116
105Aplasia/Hypoplasia of the sacrum (HP:0008517)2.04750075
106Abnormal protein glycosylation (HP:0012346)2.01548847
107Abnormal glycosylation (HP:0012345)2.01548847
108Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.01548847
109Abnormal protein N-linked glycosylation (HP:0012347)2.01548847
110Myoglobinuria (HP:0002913)2.00386901
111Hypobetalipoproteinemia (HP:0003563)2.00035783
112Agnosia (HP:0010524)1.99368261
113Muscle fiber inclusion bodies (HP:0100299)1.98521970
114Horseshoe kidney (HP:0000085)1.97613522
115Exercise intolerance (HP:0003546)1.97518707
116Abnormality of aspartate family amino acid metabolism (HP:0010899)1.96601012
117Respiratory failure (HP:0002878)1.95377091
118Ketoacidosis (HP:0001993)1.94039658
119Exertional dyspnea (HP:0002875)1.93885548
120Opisthotonus (HP:0002179)1.93593266
121Hypoglycemic coma (HP:0001325)1.93494627
122Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.93241810
123Aplasia involving forearm bones (HP:0009822)1.92963705
124Absent forearm bone (HP:0003953)1.92963705
125Neoplasm of the pancreas (HP:0002894)1.91057318
126Testicular atrophy (HP:0000029)1.90267501
127Gliosis (HP:0002171)1.89550081
128Gout (HP:0001997)1.88686708
129Abnormality of aromatic amino acid family metabolism (HP:0004338)1.86808923
130Hyperammonemia (HP:0001987)1.85981406
131Abnormality of renal resorption (HP:0011038)1.84723772
132Delayed CNS myelination (HP:0002188)1.80128923
133Exercise-induced muscle cramps (HP:0003710)1.80078304
134Abnormality of sulfur amino acid metabolism (HP:0004339)1.78721941
135Type 2 muscle fiber atrophy (HP:0003554)1.77045253
136Ketosis (HP:0001946)1.76741788
137X-linked dominant inheritance (HP:0001423)1.75458530
138Metabolic acidosis (HP:0001942)1.75448614
139Abnormality of fatty-acid metabolism (HP:0004359)1.72937421

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.26062456
2VRK24.53689671
3WEE14.52934050
4EIF2AK13.67015826
5STK163.20854533
6NME23.16538282
7TSSK62.90776733
8BRSK22.83491202
9EIF2AK32.81378008
10PLK42.51645446
11EPHA22.40371535
12LIMK12.32396053
13CDC72.29183402
14NEK12.21118267
15SRPK12.19288208
16BCKDK1.92048662
17PIM21.89071223
18TTK1.88905541
19PLK11.80779554
20NEK21.80042968
21VRK11.71198730
22BRSK11.66081614
23OBSCN1.61959856
24ACVR1B1.58275216
25TESK21.57837697
26ZAK1.56484448
27PLK31.49885360
28NUAK11.48755814
29IRAK31.45957177
30PDK41.43680783
31PDK31.43680783
32NME11.35350479
33AURKB1.35252691
34AURKA1.34029117
35DYRK31.31679006
36ATR1.26938407
37AKT31.26887993
38TRIM281.24912179
39PHKG21.24618185
40PHKG11.24618185
41MAP4K21.18851731
42CDK71.17208516
43PDK21.15516088
44CHEK21.14958071
45CCNB11.13110064
46RPS6KA41.11760745
47TLK11.09869168
48RPS6KB21.08509303
49PASK1.07773609
50BRAF1.05951217
51MAP3K111.03947767
52FLT31.03083973
53MKNK10.98890049
54CDK40.97953861
55MAP3K80.95866671
56ARAF0.95465403
57TAF10.94594320
58EIF2AK20.93979875
59KDR0.93959007
60CSNK1G30.86883420
61MAP3K30.82002810
62MAP3K120.81238563
63MKNK20.79791316
64ABL20.79220255
65CHEK10.79071979
66PIM10.77719666
67CSNK2A10.76932884
68PINK10.75594299
69MUSK0.74630948
70PBK0.73363853
71SCYL20.72373192
72PRKCI0.71901920
73CSNK2A20.71412463
74IRAK40.71403939
75CLK10.71094093
76WNK30.67607073
77PAK10.67368675
78PNCK0.63743754
79PAK40.63584749
80STK100.63430632
81CSNK1G10.62147863
82CDK80.61914018
83STK40.61389035
84MAP2K70.60709510
85STK38L0.60181881
86MAP2K30.59787346
87MST1R0.59759793
88MST40.59304454
89MAPKAPK30.57225298
90TESK10.56031521
91GRK10.52835112
92TAOK20.50863789
93CSNK1G20.50149081
94* CDK20.49693900
95MAP2K60.48885156
96CSNK1A1L0.48142302
97ATM0.45314634
98DAPK30.45135522
99MARK30.43492523
100MAPKAPK50.43206030
101INSRR0.39116801
102IKBKB0.39083807
103ADRBK20.38010570
104RPS6KA50.36874944
105MAP4K10.36816710
106DYRK20.36486679
107DAPK10.33090402
108LRRK20.32911833
109WNK40.32197130
110CDK10.31868126
111TGFBR10.29696427
112KIT0.29197842
113MAP3K50.27763309
114CSNK1A10.27363726
115ZAP700.26967897
116CAMK2G0.26540189
117ALK0.25580345
118ILK0.22902397
119TIE10.22467369
120STK240.22440538
121MAPK110.22307797
122MELK0.21936361
123TYK20.20828433
124CSNK1E0.20380179
125CDK60.20182993
126MAPKAPK20.19457158
127NEK90.19156921
128RPS6KB10.18577958
129MYLK0.15810281
130AKT20.14005067

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.38635643
2DNA replication_Homo sapiens_hsa030303.85936490
3RNA polymerase_Homo sapiens_hsa030203.73748509
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.48773435
5Ribosome_Homo sapiens_hsa030103.31352400
6Mismatch repair_Homo sapiens_hsa034303.23431833
7Pyrimidine metabolism_Homo sapiens_hsa002402.68232268
8RNA transport_Homo sapiens_hsa030132.60997999
9Spliceosome_Homo sapiens_hsa030402.46600521
10Homologous recombination_Homo sapiens_hsa034402.38848048
11One carbon pool by folate_Homo sapiens_hsa006702.36321344
12Base excision repair_Homo sapiens_hsa034102.31484505
13Nucleotide excision repair_Homo sapiens_hsa034202.30720282
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.27098345
15Vitamin B6 metabolism_Homo sapiens_hsa007502.20265927
16Folate biosynthesis_Homo sapiens_hsa007901.80769812
17Cell cycle_Homo sapiens_hsa041101.70935959
18Basal transcription factors_Homo sapiens_hsa030221.61654469
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.56696608
20Cysteine and methionine metabolism_Homo sapiens_hsa002701.51938966
21Fanconi anemia pathway_Homo sapiens_hsa034601.51146830
22Drug metabolism - other enzymes_Homo sapiens_hsa009831.51094282
23Purine metabolism_Homo sapiens_hsa002301.45928859
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45274207
25Pentose phosphate pathway_Homo sapiens_hsa000301.44890860
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.44613298
27Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.43931228
28Protein export_Homo sapiens_hsa030601.42957925
29Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.39500302
30Biosynthesis of amino acids_Homo sapiens_hsa012301.35144668
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.34843426
32Non-homologous end-joining_Homo sapiens_hsa034501.34511907
33Sulfur metabolism_Homo sapiens_hsa009201.34321764
34RNA degradation_Homo sapiens_hsa030181.33833713
35Cardiac muscle contraction_Homo sapiens_hsa042601.31668494
36Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.29492248
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.27066506
38Sulfur relay system_Homo sapiens_hsa041221.23277156
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.20844435
40Oxidative phosphorylation_Homo sapiens_hsa001901.20103713
41Carbon metabolism_Homo sapiens_hsa012001.18493094
42Parkinsons disease_Homo sapiens_hsa050121.15714749
43Selenocompound metabolism_Homo sapiens_hsa004501.13715358
44p53 signaling pathway_Homo sapiens_hsa041151.05855518
45Glutathione metabolism_Homo sapiens_hsa004801.03811139
46Huntingtons disease_Homo sapiens_hsa050161.03275490
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01854269
48Regulation of autophagy_Homo sapiens_hsa041400.99623161
49Fructose and mannose metabolism_Homo sapiens_hsa000510.97623113
50Butanoate metabolism_Homo sapiens_hsa006500.93230442
51Epstein-Barr virus infection_Homo sapiens_hsa051690.93079983
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.90231326
53mRNA surveillance pathway_Homo sapiens_hsa030150.79379514
54Arginine and proline metabolism_Homo sapiens_hsa003300.73715379
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.71983316
56Metabolic pathways_Homo sapiens_hsa011000.69943269
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68737533
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65767706
59Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.65463074
60Antigen processing and presentation_Homo sapiens_hsa046120.63780686
61Pyruvate metabolism_Homo sapiens_hsa006200.63541293
62Steroid biosynthesis_Homo sapiens_hsa001000.61071984
63Galactose metabolism_Homo sapiens_hsa000520.60951001
64Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58387882
65beta-Alanine metabolism_Homo sapiens_hsa004100.57640886
66Phenylalanine metabolism_Homo sapiens_hsa003600.54541711
67Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53275361
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52454430
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.51622338
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.51533559
71Propanoate metabolism_Homo sapiens_hsa006400.50793947
72Peroxisome_Homo sapiens_hsa041460.50614881
73Vitamin digestion and absorption_Homo sapiens_hsa049770.50458424
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48982447
75Legionellosis_Homo sapiens_hsa051340.48897083
76Caffeine metabolism_Homo sapiens_hsa002320.46689497
77Alzheimers disease_Homo sapiens_hsa050100.45947893
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42930607
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42228694
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.41061844
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.39736645
82Herpes simplex infection_Homo sapiens_hsa051680.39218283
83Arachidonic acid metabolism_Homo sapiens_hsa005900.38303374
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.37830324
85Chemical carcinogenesis_Homo sapiens_hsa052040.37575382
86Tyrosine metabolism_Homo sapiens_hsa003500.36088710
87Oocyte meiosis_Homo sapiens_hsa041140.34927476
88Systemic lupus erythematosus_Homo sapiens_hsa053220.34478381
89Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.34226129
90Fatty acid degradation_Homo sapiens_hsa000710.34029403
91Retinol metabolism_Homo sapiens_hsa008300.32205687
92N-Glycan biosynthesis_Homo sapiens_hsa005100.30972424
93Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.29194129
94Tryptophan metabolism_Homo sapiens_hsa003800.24632861
95Histidine metabolism_Homo sapiens_hsa003400.24275286
96Starch and sucrose metabolism_Homo sapiens_hsa005000.24241049
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.24150692
98Collecting duct acid secretion_Homo sapiens_hsa049660.23511076
99Linoleic acid metabolism_Homo sapiens_hsa005910.21377644
100Phototransduction_Homo sapiens_hsa047440.20739873
101Fat digestion and absorption_Homo sapiens_hsa049750.19491480
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.18111214
103* Viral carcinogenesis_Homo sapiens_hsa052030.18004296
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.17961817
105Arginine biosynthesis_Homo sapiens_hsa002200.16926228
106Fatty acid elongation_Homo sapiens_hsa000620.16484611
107Renin-angiotensin system_Homo sapiens_hsa046140.15974128
108Steroid hormone biosynthesis_Homo sapiens_hsa001400.15503226
109SNARE interactions in vesicular transport_Homo sapiens_hsa041300.15472320
110Fatty acid metabolism_Homo sapiens_hsa012120.10732136

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