MRPS15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.47129079
2viral transcription (GO:0019083)6.42690552
3translational termination (GO:0006415)6.26951617
4DNA deamination (GO:0045006)6.00815526
5ribosomal small subunit biogenesis (GO:0042274)5.82944121
6ribosomal large subunit biogenesis (GO:0042273)5.68888349
7translational elongation (GO:0006414)5.68045750
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.50809924
9cotranslational protein targeting to membrane (GO:0006613)5.38212679
10protein targeting to ER (GO:0045047)5.36795926
11maturation of SSU-rRNA (GO:0030490)5.23731170
12chaperone-mediated protein transport (GO:0072321)5.23302982
13translational initiation (GO:0006413)5.10387766
14protein localization to endoplasmic reticulum (GO:0070972)5.09524527
15establishment of protein localization to endoplasmic reticulum (GO:0072599)5.08925016
16nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.89772333
17cellular protein complex disassembly (GO:0043624)4.89589265
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.87177127
19viral life cycle (GO:0019058)4.86372123
20ATP synthesis coupled proton transport (GO:0015986)4.62490633
21energy coupled proton transport, down electrochemical gradient (GO:0015985)4.62490633
22proteasome assembly (GO:0043248)4.50928645
23* translation (GO:0006412)4.42583786
24formation of translation preinitiation complex (GO:0001731)4.42520487
25ribonucleoprotein complex biogenesis (GO:0022613)4.40421273
26mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.38988649
27DNA strand elongation involved in DNA replication (GO:0006271)4.34684518
28protein complex disassembly (GO:0043241)4.28301385
29telomere maintenance via semi-conservative replication (GO:0032201)4.27861828
30DNA strand elongation (GO:0022616)4.12038858
31negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.10214532
32macromolecular complex disassembly (GO:0032984)4.09376815
33deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.01253305
34positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.75057077
35cellular component biogenesis (GO:0044085)3.72965135
36protein complex biogenesis (GO:0070271)3.71365419
37regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.70923883
38rRNA processing (GO:0006364)3.70580259
39negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.70533544
40negative regulation of ligase activity (GO:0051352)3.70533544
41mitochondrial respiratory chain complex assembly (GO:0033108)3.68433894
42telomere maintenance via recombination (GO:0000722)3.66581600
43oxidative phosphorylation (GO:0006119)3.66428271
44nuclear-transcribed mRNA catabolic process (GO:0000956)3.66033417
45anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.65439296
46protein localization to mitochondrion (GO:0070585)3.64981283
47mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.63255401
48mitochondrial respiratory chain complex I assembly (GO:0032981)3.63255401
49NADH dehydrogenase complex assembly (GO:0010257)3.63255401
50rRNA metabolic process (GO:0016072)3.61043088
51DNA replication initiation (GO:0006270)3.60177465
52protein targeting to membrane (GO:0006612)3.57755968
53pseudouridine synthesis (GO:0001522)3.56962224
54antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.56013764
55regulation of mitochondrial translation (GO:0070129)3.53892266
56respiratory chain complex IV assembly (GO:0008535)3.52972036
57regulation of cellular amino acid metabolic process (GO:0006521)3.51255441
58protein neddylation (GO:0045116)3.50763470
59DNA replication checkpoint (GO:0000076)3.48598878
60spliceosomal snRNP assembly (GO:0000387)3.46866577
61DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.46388507
62ribosome biogenesis (GO:0042254)3.45472736
63mRNA catabolic process (GO:0006402)3.45443734
64intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.39839561
65signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.39839561
66antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.39079015
67signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.36561415
68signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.36561415
69signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.36561415
70signal transduction involved in DNA integrity checkpoint (GO:0072401)3.32670102
71signal transduction involved in DNA damage checkpoint (GO:0072422)3.32670102
72inner mitochondrial membrane organization (GO:0007007)3.31901870
73telomere maintenance via telomere lengthening (GO:0010833)3.31249159
74mitotic recombination (GO:0006312)3.30751810
75DNA unwinding involved in DNA replication (GO:0006268)3.30751338
76RNA catabolic process (GO:0006401)3.30023361
77signal transduction involved in cell cycle checkpoint (GO:0072395)3.26873156
78positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.26504864
79respiratory electron transport chain (GO:0022904)3.25454597
80exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.25337355
81folic acid-containing compound biosynthetic process (GO:0009396)3.24786930
82cullin deneddylation (GO:0010388)3.23610587
83cytochrome complex assembly (GO:0017004)3.23215261
84protein deneddylation (GO:0000338)3.22534628
85mitochondrial transport (GO:0006839)3.20527012
86electron transport chain (GO:0022900)3.17099637
87positive regulation of ligase activity (GO:0051351)3.16174259
88L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.14752534
89rRNA methylation (GO:0031167)3.11546315
90mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.11538993
91L-serine metabolic process (GO:0006563)3.10781716
92nucleobase biosynthetic process (GO:0046112)3.10189456
93aerobic respiration (GO:0009060)3.10005873
94histone exchange (GO:0043486)3.09809163
95rRNA modification (GO:0000154)3.09544479
96tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.08947446
97RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.08947446
98nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.08933529
99establishment of integrated proviral latency (GO:0075713)3.08867070
100transcription from mitochondrial promoter (GO:0006390)3.08611056
101nucleobase-containing small molecule interconversion (GO:0015949)3.08104103
102transcription elongation from RNA polymerase III promoter (GO:0006385)3.06483686
103termination of RNA polymerase III transcription (GO:0006386)3.06483686
104spliceosomal complex assembly (GO:0000245)3.06045583
105ATP biosynthetic process (GO:0006754)3.05107992
106DNA damage response, detection of DNA damage (GO:0042769)3.04725562
107regulation of ligase activity (GO:0051340)3.04487005
108establishment of viral latency (GO:0019043)3.03332130
109nucleotide-excision repair, DNA gap filling (GO:0006297)3.02034334
110CENP-A containing nucleosome assembly (GO:0034080)3.01947135
111chromatin remodeling at centromere (GO:0031055)3.01002166
112purine nucleoside triphosphate biosynthetic process (GO:0009145)2.98900383
113ribosome assembly (GO:0042255)2.96687831
114cell cycle G1/S phase transition (GO:0044843)2.96001248
115G1/S transition of mitotic cell cycle (GO:0000082)2.96001248
116pteridine-containing compound biosynthetic process (GO:0042559)2.94662680
117regulation of protein heterodimerization activity (GO:0043497)2.94526795
118IMP biosynthetic process (GO:0006188)2.91746259
119purine nucleobase biosynthetic process (GO:0009113)2.89104893
120positive regulation of cell cycle arrest (GO:0071158)2.88929919
121pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.88476365
122regulation of ubiquitin-protein transferase activity (GO:0051438)2.88373310
123transcription-coupled nucleotide-excision repair (GO:0006283)2.86259251
124protein targeting to mitochondrion (GO:0006626)2.84912068
125regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.83484084
126mitotic metaphase plate congression (GO:0007080)2.83044369
127establishment of protein localization to mitochondrion (GO:0072655)2.82525172

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.22283400
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.50976811
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.48481377
4* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.48749913
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.41278077
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.36878937
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.34790085
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.23454245
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.12693576
10* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.93568276
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89723041
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.76103838
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.68492030
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.60601111
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.53189917
16XRN2_22483619_ChIP-Seq_HELA_Human2.53082396
17E2F4_17652178_ChIP-ChIP_JURKAT_Human2.50143354
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.46078305
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.36297196
20DCP1A_22483619_ChIP-Seq_HELA_Human2.34368276
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.31718641
22VDR_23849224_ChIP-Seq_CD4+_Human2.29722170
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23650512
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.22502383
25* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.17207779
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13764387
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.13129888
28* FOXP3_21729870_ChIP-Seq_TREG_Human2.03592802
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.01646562
30GABP_19822575_ChIP-Seq_HepG2_Human1.98939907
31* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.95928942
32* TTF2_22483619_ChIP-Seq_HELA_Human1.84899894
33FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.79871238
34* SRF_21415370_ChIP-Seq_HL-1_Mouse1.74796835
35* YY1_21170310_ChIP-Seq_MESCs_Mouse1.72872292
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67326390
37* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.65476204
38CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64130518
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.62948596
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.57951368
41CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.56548624
42ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56063623
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.54484137
44PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53075487
45* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.52993823
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49104065
47* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.48261720
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.47783536
49* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.46108512
50ELK1_19687146_ChIP-ChIP_HELA_Human1.44780402
51MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.44191742
52KDM5A_27292631_Chip-Seq_BREAST_Human1.42750229
53MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.42119782
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41196480
55PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.38750730
56BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.34937629
57* CIITA_25753668_ChIP-Seq_RAJI_Human1.34562203
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.33394605
59AR_21909140_ChIP-Seq_LNCAP_Human1.28407537
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.27943951
61VDR_21846776_ChIP-Seq_THP-1_Human1.26748760
62MYC_22102868_ChIP-Seq_BL_Human1.25595360
63ELK1_22589737_ChIP-Seq_MCF10A_Human1.22413727
64* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21449922
65TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19775042
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18913016
67SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.18650601
68SPI1_23547873_ChIP-Seq_NB4_Human1.14910134
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.14423227
70STAT3_1855785_ChIP-Seq_MESCs_Mouse1.14293867
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13930416
72* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13223445
73* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.11471561
74* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11087236
75POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09830581
76E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09692695
77HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.09569571
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.08736080
79POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08554663
80CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04810805
81CTCF_18555785_ChIP-Seq_MESCs_Mouse1.01903549
82* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.00886063
83* TFEB_21752829_ChIP-Seq_HELA_Human0.99715751
84SOX2_18555785_ChIP-Seq_MESCs_Mouse0.99405746
85RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.98309299
86MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.96468752
87SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96461852
88HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.95877720
89KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.95429571
90GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95378226
91CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.95332528
92MYC_18940864_ChIP-ChIP_HL60_Human0.95140009
93KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.94645387
94DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94151819
95TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94149263
96KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94027835
97HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.93608326
98SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.93123335
99ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.91811703
100SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91438876
101SOX17_20123909_ChIP-Seq_XEN_Mouse0.88683006
102ZNF263_19887448_ChIP-Seq_K562_Human0.88506652
103IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.86003271
104TBX5_21415370_ChIP-Seq_HL-1_Mouse0.85871584
105NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.85677598
106* FOXP1_21924763_ChIP-Seq_HESCs_Human0.85483784
107* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.84848097
108PADI4_21655091_ChIP-ChIP_MCF-7_Human0.83841027
109SOX2_18692474_ChIP-Seq_MEFs_Mouse0.79932358
110CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.79304405
111NANOG_16153702_ChIP-ChIP_HESCs_Human0.77439583
112ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.76705837
113TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.75412696
114CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.72033548

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.20776409
2MP0004957_abnormal_blastocyst_morpholog4.31604392
3MP0003111_abnormal_nucleus_morphology3.49813683
4MP0010094_abnormal_chromosome_stability3.26304689
5MP0003077_abnormal_cell_cycle3.24472141
6MP0003806_abnormal_nucleotide_metabolis3.09667157
7MP0006036_abnormal_mitochondrial_physio2.78823535
8MP0008932_abnormal_embryonic_tissue2.68140507
9MP0009379_abnormal_foot_pigmentation2.46448836
10MP0003186_abnormal_redox_activity2.38367500
11MP0008058_abnormal_DNA_repair2.34114913
12MP0002837_dystrophic_cardiac_calcinosis2.29212150
13MP0002396_abnormal_hematopoietic_system2.28355517
14MP0003941_abnormal_skin_development2.28216001
15MP0008057_abnormal_DNA_replication2.28016997
16MP0010352_gastrointestinal_tract_polyps2.18874328
17MP0006292_abnormal_olfactory_placode2.18552988
18MP0006035_abnormal_mitochondrial_morpho2.17623142
19MP0000490_abnormal_crypts_of2.13552869
20MP0009697_abnormal_copulation2.10135334
21MP0009333_abnormal_splenocyte_physiolog2.08904205
22MP0008007_abnormal_cellular_replicative2.05344995
23MP0000372_irregular_coat_pigmentation1.95313517
24MP0000358_abnormal_cell_content/1.79774059
25MP0001730_embryonic_growth_arrest1.72734262
26MP0001853_heart_inflammation1.69412415
27MP0004145_abnormal_muscle_electrophysio1.67643484
28MP0004147_increased_porphyrin_level1.61485186
29MP0009785_altered_susceptibility_to1.60903450
30MP0010030_abnormal_orbit_morphology1.59722183
31MP0001835_abnormal_antigen_presentation1.58107318
32MP0001661_extended_life_span1.56571833
33MP0000350_abnormal_cell_proliferation1.55282034
34MP0005670_abnormal_white_adipose1.54075781
35MP0003656_abnormal_erythrocyte_physiolo1.53378600
36MP0002938_white_spotting1.52647197
37MP0000313_abnormal_cell_death1.49907836
38MP0000858_altered_metastatic_potential1.49441886
39MP0003436_decreased_susceptibility_to1.49119207
40MP0005397_hematopoietic_system_phenotyp1.48305869
41MP0001545_abnormal_hematopoietic_system1.48305869
42MP0003221_abnormal_cardiomyocyte_apopto1.42888260
43MP0002163_abnormal_gland_morphology1.41167765
44MP0000750_abnormal_muscle_regeneration1.40940977
45MP0002019_abnormal_tumor_incidence1.40545955
46MP0004233_abnormal_muscle_weight1.37463611
47MP0005408_hypopigmentation1.36314585
48MP0003123_paternal_imprinting1.35756718
49MP0002398_abnormal_bone_marrow1.35614271
50MP0002722_abnormal_immune_system1.35042349
51MP0003763_abnormal_thymus_physiology1.34054049
52MP0002160_abnormal_reproductive_system1.33091209
53MP0000689_abnormal_spleen_morphology1.32961423
54MP0001529_abnormal_vocalization1.32289877
55MP0000685_abnormal_immune_system1.30713615
56MP0005332_abnormal_amino_acid1.30267874
57MP0003567_abnormal_fetal_cardiomyocyte1.29893365
58MP0003786_premature_aging1.29026182
59MP0003646_muscle_fatigue1.28680453
60MP0002080_prenatal_lethality1.26991543
61MP0001697_abnormal_embryo_size1.24893292
62MP0005671_abnormal_response_to1.23340397
63MP0002429_abnormal_blood_cell1.18980417
64MP0000749_muscle_degeneration1.18121742
65MP0000703_abnormal_thymus_morphology1.17022325
66MP0005025_abnormal_response_to1.16885728
67MP0009840_abnormal_foam_cell1.12686424
68MP0005330_cardiomyopathy1.12420842
69MP0003718_maternal_effect1.10899608
70MP0004808_abnormal_hematopoietic_stem1.09703840
71MP0001764_abnormal_homeostasis1.07544222
72MP0000343_altered_response_to1.05281364
73MP0002405_respiratory_system_inflammati1.04456892
74MP0002210_abnormal_sex_determination1.04191814
75MP0001293_anophthalmia1.04125145
76MP0000716_abnormal_immune_system1.03782197
77MP0004036_abnormal_muscle_relaxation1.03491947
78MP0008789_abnormal_olfactory_epithelium1.02270446
79MP0008995_early_reproductive_senescence1.01040207
80MP0001800_abnormal_humoral_immune0.98793854
81MP0001672_abnormal_embryogenesis/_devel0.98692132
82MP0005380_embryogenesis_phenotype0.98692132
83MP0003984_embryonic_growth_retardation0.98238760
84MP0005319_abnormal_enzyme/_coenzyme0.98198067
85MP0002420_abnormal_adaptive_immunity0.97640562
86MP0001819_abnormal_immune_cell0.97429759
87MP0005075_abnormal_melanosome_morpholog0.96992376
88MP0009672_abnormal_birth_weight0.96763375
89MP0002148_abnormal_hypersensitivity_rea0.96623502
90MP0005000_abnormal_immune_tolerance0.95315063
91MP0002088_abnormal_embryonic_growth/wei0.94514296
92MP0001881_abnormal_mammary_gland0.94415593
93MP0002452_abnormal_antigen_presenting0.93581974
94MP0005389_reproductive_system_phenotype0.93293083
95MP0005266_abnormal_metabolism0.92778025
96MP0001727_abnormal_embryo_implantation0.92257519
97MP0005501_abnormal_skin_physiology0.91478614
98MP0008469_abnormal_protein_level0.91168407
99MP0002132_abnormal_respiratory_system0.90967199
100MP0002723_abnormal_immune_serum0.89816282
101MP0004185_abnormal_adipocyte_glucose0.89578584
102MP0005451_abnormal_body_composition0.87777630
103MP0002269_muscular_atrophy0.87011896
104MP0005084_abnormal_gallbladder_morpholo0.85795179
105MP0003315_abnormal_perineum_morphology0.84490820
106MP0001929_abnormal_gametogenesis0.83304216
107MP0000049_abnormal_middle_ear0.80890935
108MP0005636_abnormal_mineral_homeostasis0.79949776
109MP0001145_abnormal_male_reproductive0.79300369
110MP0003937_abnormal_limbs/digits/tail_de0.78044209
111MP0001919_abnormal_reproductive_system0.77583293
112MP0004084_abnormal_cardiac_muscle0.76564573
113MP0002084_abnormal_developmental_patter0.75988880
114MP0005083_abnormal_biliary_tract0.75041314
115MP0002102_abnormal_ear_morphology0.74475461
116MP0003724_increased_susceptibility_to0.74097276
117MP0003136_yellow_coat_color0.74053653
118MP0002086_abnormal_extraembryonic_tissu0.73567239
119MP0001845_abnormal_inflammatory_respons0.73475227
120MP0005379_endocrine/exocrine_gland_phen0.73273271
121MP0000747_muscle_weakness0.73149886
122MP0006054_spinal_hemorrhage0.72447799
123MP0000598_abnormal_liver_morphology0.72433477
124MP0000477_abnormal_intestine_morphology0.72009053
125MP0000653_abnormal_sex_gland0.71378485
126MP0006072_abnormal_retinal_apoptosis0.70639705
127MP0002106_abnormal_muscle_physiology0.70526020
128MP0010155_abnormal_intestine_physiology0.70306663
129MP0005464_abnormal_platelet_physiology0.69789590
130MP0002796_impaired_skin_barrier0.68758332
131MP0005384_cellular_phenotype0.68102357
132MP0002085_abnormal_embryonic_tissue0.67505841
133MP0002876_abnormal_thyroid_physiology0.66974944
134MP0003866_abnormal_defecation0.66811969
135MP0010307_abnormal_tumor_latency0.66664972
136MP0004197_abnormal_fetal_growth/weight/0.66580646
137MP0005376_homeostasis/metabolism_phenot0.66025784
138MP0002419_abnormal_innate_immunity0.65983962
139MP0004215_abnormal_myocardial_fiber0.65150056
140MP0002138_abnormal_hepatobiliary_system0.64955979
141MP0003137_abnormal_impulse_conducting0.64344812
142MP0008875_abnormal_xenobiotic_pharmacok0.63115514
143MP0004087_abnormal_muscle_fiber0.62758934
144MP0000678_abnormal_parathyroid_gland0.62453181
145MP0003011_delayed_dark_adaptation0.61713208
146MP0000759_abnormal_skeletal_muscle0.60022012
147MP0005395_other_phenotype0.59940818
148MP0002090_abnormal_vision0.59143705

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)7.13212763
2Abnormal number of erythroid precursors (HP:0012131)5.84167539
3Decreased activity of mitochondrial respiratory chain (HP:0008972)4.90138281
4Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.90138281
5Reticulocytopenia (HP:0001896)4.57560027
6Microvesicular hepatic steatosis (HP:0001414)4.41800932
7Macrocytic anemia (HP:0001972)4.35698965
8Hepatocellular necrosis (HP:0001404)4.30790704
9Pallor (HP:0000980)4.16879649
10Hepatic necrosis (HP:0002605)4.16348327
11Mitochondrial inheritance (HP:0001427)4.08610124
12Increased CSF lactate (HP:0002490)3.90912537
13Acute necrotizing encephalopathy (HP:0006965)3.90319720
14Abnormal mitochondria in muscle tissue (HP:0008316)3.85236244
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.83534708
16Increased hepatocellular lipid droplets (HP:0006565)3.64804265
17Increased serum lactate (HP:0002151)3.62399142
18Oral leukoplakia (HP:0002745)3.53268823
19Lipid accumulation in hepatocytes (HP:0006561)3.52724573
20Increased intramyocellular lipid droplets (HP:0012240)3.48127369
21Acute encephalopathy (HP:0006846)3.41562367
22Increased muscle lipid content (HP:0009058)3.34564324
23Lactic acidosis (HP:0003128)3.31569992
24Aplastic anemia (HP:0001915)3.30367565
25Exercise intolerance (HP:0003546)3.21487892
26Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.13751846
27Poor head control (HP:0002421)3.10852573
28Cerebral edema (HP:0002181)3.01907248
29Exertional dyspnea (HP:0002875)3.01512557
30Progressive macrocephaly (HP:0004481)2.97765034
31Progressive muscle weakness (HP:0003323)2.97661876
32Birth length less than 3rd percentile (HP:0003561)2.94530688
33Multiple enchondromatosis (HP:0005701)2.86200950
34Aplasia/Hypoplasia of the sacrum (HP:0008517)2.85005327
35Respiratory failure (HP:0002878)2.81986659
36Microretrognathia (HP:0000308)2.80102095
37Renal Fanconi syndrome (HP:0001994)2.70299204
38Rhabdomyolysis (HP:0003201)2.68639773
39Rough bone trabeculation (HP:0100670)2.64953579
40Increased serum pyruvate (HP:0003542)2.61332805
41Abnormality of glycolysis (HP:0004366)2.61332805
42Abnormality of dicarboxylic acid metabolism (HP:0010995)2.60656891
43Dicarboxylic aciduria (HP:0003215)2.60656891
44Abnormality of methionine metabolism (HP:0010901)2.55688562
45Leukodystrophy (HP:0002415)2.49865343
46Respiratory difficulties (HP:0002880)2.48801546
47Nausea (HP:0002018)2.44540349
48Breast hypoplasia (HP:0003187)2.44155071
49Thrombocytosis (HP:0001894)2.40685363
50Type I transferrin isoform profile (HP:0003642)2.38128523
51Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.35522527
52Abnormality of alanine metabolism (HP:0010916)2.35522527
53Hyperalaninemia (HP:0003348)2.35522527
54Abnormal hemoglobin (HP:0011902)2.34866393
55Abnormality of serum amino acid levels (HP:0003112)2.34809684
56Optic disc pallor (HP:0000543)2.34330702
57Trismus (HP:0000211)2.33881752
58Abnormality of the anterior horn cell (HP:0006802)2.32907679
59Degeneration of anterior horn cells (HP:0002398)2.32907679
60Abnormality of reticulocytes (HP:0004312)2.31842609
61Chromosomal breakage induced by crosslinking agents (HP:0003221)2.31093939
62CNS demyelination (HP:0007305)2.29555199
63Absent thumb (HP:0009777)2.29256163
64Pancytopenia (HP:0001876)2.29091995
65Nemaline bodies (HP:0003798)2.27176106
66Increased serum ferritin (HP:0003281)2.25925935
67Emotional lability (HP:0000712)2.25632472
68Cerebral hypomyelination (HP:0006808)2.25453750
69Petechiae (HP:0000967)2.18578549
703-Methylglutaconic aciduria (HP:0003535)2.18053722
71Ragged-red muscle fibers (HP:0003200)2.15419300
72Elevated erythrocyte sedimentation rate (HP:0003565)2.15023382
73Hyperglycinemia (HP:0002154)2.13644826
74Muscle fiber inclusion bodies (HP:0100299)2.10407598
75Premature graying of hair (HP:0002216)2.09711003
76Chromsome breakage (HP:0040012)2.09305082
77Abnormality of the heme biosynthetic pathway (HP:0010472)2.08949730
78Sparse eyelashes (HP:0000653)2.08775262
79Selective tooth agenesis (HP:0001592)2.07239079
80Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.07157679
81Reduced antithrombin III activity (HP:0001976)2.04936507
82Meckel diverticulum (HP:0002245)2.04933374
83Methylmalonic aciduria (HP:0012120)1.99665507
84Abnormality of aspartate family amino acid metabolism (HP:0010899)1.94835200
85Abnormality of the preputium (HP:0100587)1.94281661
86Glycosuria (HP:0003076)1.92658292
87Abnormality of urine glucose concentration (HP:0011016)1.92658292
88Abnormality of the ileum (HP:0001549)1.92599522
89Cellular immunodeficiency (HP:0005374)1.91786201
90Stenosis of the external auditory canal (HP:0000402)1.91672549
91Gout (HP:0001997)1.89172828
92X-linked dominant inheritance (HP:0001423)1.88390876
93Muscle fiber atrophy (HP:0100295)1.88042693
94Lethargy (HP:0001254)1.87746516
95Horseshoe kidney (HP:0000085)1.87468919
96IgM deficiency (HP:0002850)1.87160553
97Angiofibromas (HP:0010615)1.86314904
98Adenoma sebaceum (HP:0009720)1.86314904
9911 pairs of ribs (HP:0000878)1.85699403
100Abnormality of renal resorption (HP:0011038)1.84513720
101Testicular atrophy (HP:0000029)1.83060322
102Hyperphosphaturia (HP:0003109)1.82807729
103Hyperglycinuria (HP:0003108)1.82185033
104Exercise-induced muscle cramps (HP:0003710)1.81636967
105Abnormal trabecular bone morphology (HP:0100671)1.80516331
106Patellar aplasia (HP:0006443)1.78906231
107Carpal bone hypoplasia (HP:0001498)1.78594035
108Colon cancer (HP:0003003)1.77914794
109Aplasia/Hypoplasia of the uvula (HP:0010293)1.77255030
110Generalized aminoaciduria (HP:0002909)1.76065141
111Abnormality of iron homeostasis (HP:0011031)1.75932838
112Abnormal protein glycosylation (HP:0012346)1.75256750
113Abnormal glycosylation (HP:0012345)1.75256750
114Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.75256750
115Abnormal protein N-linked glycosylation (HP:0012347)1.75256750
116Methylmalonic acidemia (HP:0002912)1.73503972
117Abnormal lung lobation (HP:0002101)1.72431586
118Gliosis (HP:0002171)1.72376281
119Type 2 muscle fiber atrophy (HP:0003554)1.71628627
120Aplasia/Hypoplasia of the patella (HP:0006498)1.71540116
121Abnormality of sulfur amino acid metabolism (HP:0004339)1.71183951
122Cleft eyelid (HP:0000625)1.71137159
123Neoplasm of the pancreas (HP:0002894)1.66567718
124Abnormal number of incisors (HP:0011064)1.65651820
125Basal cell carcinoma (HP:0002671)1.65557272
126Amniotic constriction ring (HP:0009775)1.65427154
127Abnormality of placental membranes (HP:0011409)1.65427154
128Neoplasm of head and neck (HP:0012288)1.64802781
129Esophageal neoplasm (HP:0100751)1.64802781

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK14.81806577
2BUB14.80776615
3VRK24.55801197
4NME24.48222952
5WEE13.19278489
6PDK22.65703721
7EIF2AK32.65298946
8STK162.62146009
9TESK22.48636013
10PIM22.34056487
11TLK12.25524762
12CDC72.14029029
13MAP3K112.11176650
14ACVR1B2.06525901
15KDR1.97754235
16BCKDK1.91682458
17RPS6KB21.83364725
18VRK11.80793101
19SRPK11.76320261
20NME11.72868899
21NEK11.57785729
22ILK1.56081277
23ARAF1.53630157
24PLK41.51358862
25NEK21.46710731
26MAP4K11.45582862
27SCYL21.36377301
28BLK1.35117173
29LRRK21.28007261
30TESK11.25643937
31BRSK21.25287995
32RPS6KA41.23857843
33PLK11.23554432
34BMPR1B1.21477087
35MAP3K121.20734507
36MAPKAPK31.20204246
37DYRK31.18068610
38PKN21.17515588
39CDK71.13238826
40AURKA1.12935150
41NUAK11.11260719
42BRSK11.10141996
43AURKB1.09826848
44TTK1.02721928
45ABL21.00570677
46ERN10.99466154
47IRAK30.99210291
48MAP3K80.98614621
49FLT30.95978794
50MAP2K30.94600097
51BRAF0.91477965
52PAK10.89910516
53TGFBR10.88858671
54PAK40.87873537
55LIMK10.84615397
56ATR0.83459399
57CDK40.81315749
58CDK190.80416843
59ZAP700.80088832
60DYRK20.76625746
61EIF2AK20.76546140
62TAF10.73583003
63DAPK30.72743980
64TBK10.72115076
65CCNB10.70040142
66IRAK40.69881559
67CSNK1G30.69853415
68CSNK2A10.69518484
69PBK0.68397897
70PIM10.67494111
71TEC0.67229071
72RAF10.65924510
73EEF2K0.64949992
74DAPK10.63381583
75CSNK2A20.63209292
76TRIB30.63020354
77MAP2K60.62103404
78BTK0.61114246
79TRIM280.60435847
80STK100.59555544
81CDK80.57932479
82CHEK20.57917834
83MAP3K100.57610758
84GRK60.57358203
85CSNK1G10.56997029
86TYK20.56498385
87PASK0.54435810
88STK40.53266815
89MYLK0.52461816
90ATM0.48965703
91PHKG10.48595949
92PHKG20.48595949
93KIT0.47896104
94TAOK20.47731223
95ALK0.46845350
96MKNK10.46141744
97AKT20.45712715
98MUSK0.44878952
99CSNK1G20.43530621
100CSNK1A1L0.42015944
101TSSK60.40202988
102PLK30.39746528
103CSNK1E0.39545818
104GRK70.38950723
105ZAK0.38737549
106CDK10.38693268
107MKNK20.38667198
108ERBB40.38592295
109MAP2K20.37258873
110CDK20.35886856
111PRKCI0.35816632
112MST40.34966288
113RPS6KA60.33589533
114RPS6KC10.33364542
115RPS6KL10.33364542
116MAP3K50.32627917
117MAPK110.32402401
118PRKG20.31622682
119EPHA20.31547121
120CAMK2G0.30641970
121OBSCN0.30569238
122CHEK10.30155373
123RPS6KA50.30082463
124NEK90.29650455
125SMG10.29471499
126MOS0.28545537
127GRK10.27109084
128MST1R0.26371054
129MAP4K20.25749740
130CLK10.25131891

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030105.68592108
2Proteasome_Homo sapiens_hsa030504.42142171
3DNA replication_Homo sapiens_hsa030304.27827426
4Mismatch repair_Homo sapiens_hsa034303.34821088
5RNA polymerase_Homo sapiens_hsa030203.02479371
6Parkinsons disease_Homo sapiens_hsa050122.82049486
7Oxidative phosphorylation_Homo sapiens_hsa001902.76129729
8Spliceosome_Homo sapiens_hsa030402.71335245
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.69333216
10Pyrimidine metabolism_Homo sapiens_hsa002402.52779369
11Homologous recombination_Homo sapiens_hsa034402.39024367
12Base excision repair_Homo sapiens_hsa034102.31664556
13Nucleotide excision repair_Homo sapiens_hsa034202.25080392
14Huntingtons disease_Homo sapiens_hsa050162.05759381
15RNA transport_Homo sapiens_hsa030132.02594511
16One carbon pool by folate_Homo sapiens_hsa006701.96671655
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.81237496
18Sulfur relay system_Homo sapiens_hsa041221.73392586
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.72947522
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.71843142
21Alzheimers disease_Homo sapiens_hsa050101.71767483
22Protein export_Homo sapiens_hsa030601.62314990
23Cell cycle_Homo sapiens_hsa041101.55734202
24Fatty acid elongation_Homo sapiens_hsa000621.55615581
25Folate biosynthesis_Homo sapiens_hsa007901.47960298
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.43973269
27Pentose phosphate pathway_Homo sapiens_hsa000301.39453352
28RNA degradation_Homo sapiens_hsa030181.35418050
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.35167184
30Carbon metabolism_Homo sapiens_hsa012001.33910751
31Biosynthesis of amino acids_Homo sapiens_hsa012301.27960025
32Purine metabolism_Homo sapiens_hsa002301.20969398
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.16991751
34Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.15756041
35Vitamin B6 metabolism_Homo sapiens_hsa007501.10782727
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.10322448
37Fanconi anemia pathway_Homo sapiens_hsa034601.09851972
38Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.06626075
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.00436014
40Cardiac muscle contraction_Homo sapiens_hsa042600.99677570
41Non-homologous end-joining_Homo sapiens_hsa034500.99526958
42p53 signaling pathway_Homo sapiens_hsa041150.98755123
43Basal transcription factors_Homo sapiens_hsa030220.97509191
44Fructose and mannose metabolism_Homo sapiens_hsa000510.94009297
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89884532
46Sulfur metabolism_Homo sapiens_hsa009200.89091866
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85370922
48Glutathione metabolism_Homo sapiens_hsa004800.81660688
49Epstein-Barr virus infection_Homo sapiens_hsa051690.80422519
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76006932
51Steroid biosynthesis_Homo sapiens_hsa001000.75259487
52Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.74536301
53Drug metabolism - other enzymes_Homo sapiens_hsa009830.73746042
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.73091779
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.72585136
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.69309707
57Galactose metabolism_Homo sapiens_hsa000520.69055218
58Fatty acid metabolism_Homo sapiens_hsa012120.60995564
59Metabolic pathways_Homo sapiens_hsa011000.60534664
60Pyruvate metabolism_Homo sapiens_hsa006200.59709974
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59267112
62Antigen processing and presentation_Homo sapiens_hsa046120.59249517
63Legionellosis_Homo sapiens_hsa051340.59166605
64Herpes simplex infection_Homo sapiens_hsa051680.58236910
65Selenocompound metabolism_Homo sapiens_hsa004500.58127366
66Arginine biosynthesis_Homo sapiens_hsa002200.57305532
67Systemic lupus erythematosus_Homo sapiens_hsa053220.56800584
68mRNA surveillance pathway_Homo sapiens_hsa030150.56402636
69Cyanoamino acid metabolism_Homo sapiens_hsa004600.54038390
70Tyrosine metabolism_Homo sapiens_hsa003500.52827323
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44616186
72Thyroid cancer_Homo sapiens_hsa052160.44088113
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43978525
74Propanoate metabolism_Homo sapiens_hsa006400.43770538
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41564685
76N-Glycan biosynthesis_Homo sapiens_hsa005100.41200961
77Shigellosis_Homo sapiens_hsa051310.40897383
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40572784
79Butanoate metabolism_Homo sapiens_hsa006500.38717329
80Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.38493107
81Tryptophan metabolism_Homo sapiens_hsa003800.38421475
82Primary immunodeficiency_Homo sapiens_hsa053400.37754046
83Apoptosis_Homo sapiens_hsa042100.36264372
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.32385946
85Arginine and proline metabolism_Homo sapiens_hsa003300.31166259
86Peroxisome_Homo sapiens_hsa041460.30896651
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.30887052
88Other glycan degradation_Homo sapiens_hsa005110.30350690
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28903184
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.27786860
91Viral carcinogenesis_Homo sapiens_hsa052030.27195479
92Acute myeloid leukemia_Homo sapiens_hsa052210.26259318
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26223217
94Fatty acid degradation_Homo sapiens_hsa000710.25132348
95Leishmaniasis_Homo sapiens_hsa051400.24610232
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.23080310
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.23006980
98Intestinal immune network for IgA production_Homo sapiens_hsa046720.22962076
99HTLV-I infection_Homo sapiens_hsa051660.22623184
100Pentose and glucuronate interconversions_Homo sapiens_hsa000400.22081979
101Oocyte meiosis_Homo sapiens_hsa041140.22038262
102Chemical carcinogenesis_Homo sapiens_hsa052040.21621341
103Arachidonic acid metabolism_Homo sapiens_hsa005900.21229049
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.21124086
105Vitamin digestion and absorption_Homo sapiens_hsa049770.21010060
106Regulation of autophagy_Homo sapiens_hsa041400.20637997
107HIF-1 signaling pathway_Homo sapiens_hsa040660.20600712
108Measles_Homo sapiens_hsa051620.16664770
109Retinol metabolism_Homo sapiens_hsa008300.14805467
110Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.14702504
111Caffeine metabolism_Homo sapiens_hsa002320.14387528
112Fat digestion and absorption_Homo sapiens_hsa049750.12812928
113Bladder cancer_Homo sapiens_hsa052190.11819234
114Phenylalanine metabolism_Homo sapiens_hsa003600.11628272
115Collecting duct acid secretion_Homo sapiens_hsa049660.10535149
116Hepatitis B_Homo sapiens_hsa051610.09941767
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.09790167
118Asthma_Homo sapiens_hsa053100.09780814
119Vibrio cholerae infection_Homo sapiens_hsa051100.09201803
120Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.09096775
121Viral myocarditis_Homo sapiens_hsa054160.08232721
122Steroid hormone biosynthesis_Homo sapiens_hsa001400.08058950
123beta-Alanine metabolism_Homo sapiens_hsa004100.06324183
124Salmonella infection_Homo sapiens_hsa051320.05912144
125Renin-angiotensin system_Homo sapiens_hsa046140.05298746
126Influenza A_Homo sapiens_hsa051640.04989640
127Nitrogen metabolism_Homo sapiens_hsa009100.04390405
128Hematopoietic cell lineage_Homo sapiens_hsa046400.03414703
129SNARE interactions in vesicular transport_Homo sapiens_hsa041300.01263543

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