MROH7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.87213534
2binding of sperm to zona pellucida (GO:0007339)9.71094629
3reproduction (GO:0000003)9.54907726
4axonemal dynein complex assembly (GO:0070286)9.34729545
5epithelial cilium movement (GO:0003351)8.99593183
6regulation of cilium movement (GO:0003352)8.83231120
7spermatid development (GO:0007286)8.73042814
8motile cilium assembly (GO:0044458)8.20830010
9sperm capacitation (GO:0048240)8.18587064
10cilium movement (GO:0003341)7.97563941
11male meiosis (GO:0007140)7.56436632
12single fertilization (GO:0007338)7.33282262
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.26281306
14synaptonemal complex organization (GO:0070193)6.85366523
15synaptonemal complex assembly (GO:0007130)6.78772012
16piRNA metabolic process (GO:0034587)6.45456647
17organic cation transport (GO:0015695)6.33141538
18negative regulation of inclusion body assembly (GO:0090084)6.03107742
19fertilization (GO:0009566)5.99475691
20ventricular system development (GO:0021591)5.82737627
21spermatogenesis (GO:0007283)5.77492930
22male gamete generation (GO:0048232)5.74977632
23microtubule severing (GO:0051013)5.73725362
24calcium ion-dependent exocytosis (GO:0017156)5.71417443
25regulation of microtubule-based movement (GO:0060632)5.42213035
26regulation of inclusion body assembly (GO:0090083)5.33888313
27gamete generation (GO:0007276)5.29604450
28cell recognition (GO:0008037)5.20132802
29regulation of female gonad development (GO:2000194)5.13079285
30cellular process involved in reproduction in multicellular organism (GO:0022412)5.06244769
31cellular ketone body metabolic process (GO:0046950)4.91729098
32regulation of sarcomere organization (GO:0060297)4.87763003
33germ cell development (GO:0007281)4.82404728
34microtubule depolymerization (GO:0007019)4.69156108
35protein polyglutamylation (GO:0018095)4.61563292
36response to pheromone (GO:0019236)4.54520660
37negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.54512777
38negative regulation of translation, ncRNA-mediated (GO:0040033)4.54512777
39regulation of translation, ncRNA-mediated (GO:0045974)4.54512777
40spermatid nucleus differentiation (GO:0007289)4.53711552
41male meiosis I (GO:0007141)4.45645506
42chromosome organization involved in meiosis (GO:0070192)4.44920531
43ketone body metabolic process (GO:1902224)4.31222820
44multicellular organismal reproductive process (GO:0048609)4.17941557
45left/right pattern formation (GO:0060972)4.17629375
46establishment of protein localization to Golgi (GO:0072600)4.11836796
47musculoskeletal movement (GO:0050881)4.11037319
48multicellular organismal movement (GO:0050879)4.11037319
49NAD biosynthetic process (GO:0009435)4.00487679
50DNA methylation involved in gamete generation (GO:0043046)3.99003788
51meiotic nuclear division (GO:0007126)3.98213501
52behavioral response to nicotine (GO:0035095)3.78100556
53glycerol ether metabolic process (GO:0006662)3.77625442
54G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.74778471
55phosphatidylethanolamine biosynthetic process (GO:0006646)3.74452332
56seminiferous tubule development (GO:0072520)3.61941856
57protein localization to cilium (GO:0061512)3.51683887
58protein K48-linked deubiquitination (GO:0071108)3.51363707
59ether metabolic process (GO:0018904)3.47155745
60phosphatidylethanolamine metabolic process (GO:0046337)3.46347296
61meiosis I (GO:0007127)3.44852922
62amino-acid betaine transport (GO:0015838)3.44543969
63carnitine transport (GO:0015879)3.44543969
64response to misfolded protein (GO:0051788)3.42563727
65protein targeting to Golgi (GO:0000042)3.40110821
66multicellular organismal development (GO:0007275)3.34835767
67peptidyl-threonine dephosphorylation (GO:0035970)3.33735371
68calcium ion import (GO:0070509)3.33396853
69chromosome condensation (GO:0030261)3.31370518
70primary amino compound metabolic process (GO:1901160)3.30005955
71genitalia morphogenesis (GO:0035112)3.28688173
72tryptophan catabolic process (GO:0006569)3.27999673
73indole-containing compound catabolic process (GO:0042436)3.27999673
74indolalkylamine catabolic process (GO:0046218)3.27999673
75monoubiquitinated protein deubiquitination (GO:0035520)3.26740475
76regulation of Rab GTPase activity (GO:0032313)3.24529008
77positive regulation of Rab GTPase activity (GO:0032851)3.24529008
78reflex (GO:0060004)3.24314724
79carnitine transmembrane transport (GO:1902603)3.23928545
80chaperone-mediated protein complex assembly (GO:0051131)3.23411330
81membrane depolarization during action potential (GO:0086010)3.19737723
82retrograde transport, vesicle recycling within Golgi (GO:0000301)3.18182104
83DNA packaging (GO:0006323)3.16557984
84spinal cord motor neuron differentiation (GO:0021522)3.14374428
85intraciliary transport (GO:0042073)3.13489687
86kynurenine metabolic process (GO:0070189)3.11730143
87negative regulation of organelle assembly (GO:1902116)3.10716950
88indolalkylamine metabolic process (GO:0006586)3.09483230
89positive regulation of action potential (GO:0045760)3.06076141
90cilium organization (GO:0044782)3.04648065
91alanine transport (GO:0032328)3.04490292
92microtubule-based movement (GO:0007018)3.03700464
93detection of light stimulus involved in sensory perception (GO:0050962)3.02513043
94detection of light stimulus involved in visual perception (GO:0050908)3.02513043
95centriole replication (GO:0007099)3.02015461
96regulation of transcription involved in cell fate commitment (GO:0060850)2.97782731
97peptidyl-lysine dimethylation (GO:0018027)2.96612628
98membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.95575507
99pyridine nucleotide biosynthetic process (GO:0019363)2.93895414
100nicotinamide nucleotide biosynthetic process (GO:0019359)2.93895414
101cilium assembly (GO:0042384)2.92021382
102gamma-aminobutyric acid transport (GO:0015812)2.89799509
103glycolytic process (GO:0006096)2.85866384
104cellular component assembly involved in morphogenesis (GO:0010927)2.85009197
105chromatin silencing (GO:0006342)2.82240180
106positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.80747788
107RNA destabilization (GO:0050779)2.80380221
108lactate metabolic process (GO:0006089)2.78787066
109positive regulation of CREB transcription factor activity (GO:0032793)2.78446756
110protein localization to Golgi apparatus (GO:0034067)2.77209138
111peptidyl-glutamic acid modification (GO:0018200)2.76665419
112positive regulation of macrophage activation (GO:0043032)2.74623037
113cellular response to pH (GO:0071467)2.74279034
114sexual reproduction (GO:0019953)2.73686850
115negative regulation of sodium ion transport (GO:0010766)2.73178188
116cAMP catabolic process (GO:0006198)2.72545869
117protein K63-linked deubiquitination (GO:0070536)2.71842062
118cilium morphogenesis (GO:0060271)2.71527580
119serotonin metabolic process (GO:0042428)2.70832514
120tryptophan metabolic process (GO:0006568)2.69683161
121protein K11-linked deubiquitination (GO:0035871)2.68254281
122axoneme assembly (GO:0035082)2.68147558
123regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.67587688
124positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.67587688
125indole-containing compound metabolic process (GO:0042430)2.65558329
126interkinetic nuclear migration (GO:0022027)2.65523136
127regulation of spindle checkpoint (GO:0090231)2.61720827
128appendage development (GO:0048736)2.61494462
129limb development (GO:0060173)2.61494462
130cranial nerve morphogenesis (GO:0021602)2.59668092
131regulation of response to osmotic stress (GO:0047484)2.59136559
132quaternary ammonium group transport (GO:0015697)2.57852723
133synapsis (GO:0007129)2.54407145
134neuronal action potential (GO:0019228)2.53488187
135positive regulation of guanylate cyclase activity (GO:0031284)2.53400917
136protein refolding (GO:0042026)2.52808814
137polyol catabolic process (GO:0046174)2.52284086
138meiotic cell cycle (GO:0051321)2.45715641
139phosphatidylglycerol biosynthetic process (GO:0006655)2.41469198
140CDP-diacylglycerol biosynthetic process (GO:0016024)2.41269463
141RNA localization (GO:0006403)2.40605212
142single strand break repair (GO:0000012)2.38617079
143regulation of cilium assembly (GO:1902017)2.36858594
144alditol metabolic process (GO:0019400)2.36306167
145meiotic cell cycle process (GO:1903046)2.33910947
146regulation of inositol phosphate biosynthetic process (GO:0010919)2.33069795
147microtubule polymerization or depolymerization (GO:0031109)2.31664929
148nucleoside diphosphate phosphorylation (GO:0006165)2.24007610
149nucleus organization (GO:0006997)2.22737548
150regulation of protein kinase A signaling (GO:0010738)2.15666792
151cell wall macromolecule catabolic process (GO:0016998)12.8609906
152cell wall macromolecule metabolic process (GO:0044036)12.8609906
153fusion of sperm to egg plasma membrane (GO:0007342)12.8127604
154sperm motility (GO:0030317)12.5614291
155acrosome assembly (GO:0001675)12.1668871
156multicellular organism reproduction (GO:0032504)11.4954226
157sperm-egg recognition (GO:0035036)11.3768810
158acrosome reaction (GO:0007340)11.1661781
159cilium or flagellum-dependent cell motility (GO:0001539)10.6867644
160cell-cell recognition (GO:0009988)10.1835355

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.62327530
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.05154274
3EZH2_22144423_ChIP-Seq_EOC_Human4.42011376
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.93086637
5PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.78605871
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.78017647
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.68714401
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.63184887
9GBX2_23144817_ChIP-Seq_PC3_Human2.13314513
10ZNF274_21170338_ChIP-Seq_K562_Hela2.05873558
11CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04126980
12VDR_22108803_ChIP-Seq_LS180_Human1.99380786
13CBX2_27304074_Chip-Seq_ESCs_Mouse1.89223996
14GATA1_26923725_Chip-Seq_HPCs_Mouse1.81827633
15PCGF2_27294783_Chip-Seq_ESCs_Mouse1.79817365
16REST_21632747_ChIP-Seq_MESCs_Mouse1.78958139
17KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.76409149
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.74644135
19STAT6_21828071_ChIP-Seq_BEAS2B_Human1.74444181
20TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.73128688
21AR_21572438_ChIP-Seq_LNCaP_Human1.69496794
22JARID2_20075857_ChIP-Seq_MESCs_Mouse1.69312847
23EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.69014466
24CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.60837937
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.59812238
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.58829144
27EZH2_27304074_Chip-Seq_ESCs_Mouse1.54614424
28MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.53135515
29PCGF2_27294783_Chip-Seq_NPCs_Mouse1.52725728
30JARID2_20064375_ChIP-Seq_MESCs_Mouse1.52177340
31STAT3_23295773_ChIP-Seq_U87_Human1.52166641
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52136537
33CBP_20019798_ChIP-Seq_JUKART_Human1.52136537
34ELK4_26923725_Chip-Seq_MESODERM_Mouse1.52086316
35FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48973966
36RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.48502492
37GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.48499915
38BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48218414
39KDM2B_26808549_Chip-Seq_REH_Human1.46215233
40SMAD4_21799915_ChIP-Seq_A2780_Human1.40788385
41FLI1_21867929_ChIP-Seq_TH2_Mouse1.40520456
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40159878
43STAT1_17558387_ChIP-Seq_HELA_Human1.40073786
44WDR5_24793694_ChIP-Seq_LNCAP_Human1.38873346
45ER_23166858_ChIP-Seq_MCF-7_Human1.38810338
46P300_19829295_ChIP-Seq_ESCs_Human1.37577767
47ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.36772788
48AR_25329375_ChIP-Seq_VCAP_Human1.36551670
49TAL1_26923725_Chip-Seq_HPCs_Mouse1.36228045
50TCF4_23295773_ChIP-Seq_U87_Human1.35674365
51EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.34135038
52SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.33920824
53ARNT_22903824_ChIP-Seq_MCF-7_Human1.33844902
54GATA3_21867929_ChIP-Seq_CD8_Mouse1.33574520
55TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32737998
56TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.32138867
57NFE2_27457419_Chip-Seq_LIVER_Mouse1.30443963
58SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.29426249
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28259492
60RNF2_27304074_Chip-Seq_NSC_Mouse1.27952829
61PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.27820030
62ZFP57_27257070_Chip-Seq_ESCs_Mouse1.27737202
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.27342406
64RNF2_27304074_Chip-Seq_ESCs_Mouse1.25707171
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.25380643
66PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.25104576
67KAP1_22055183_ChIP-Seq_ESCs_Mouse1.24782818
68SMAD4_21741376_ChIP-Seq_EPCs_Human1.23467099
69RUNX1_26923725_Chip-Seq_HPCs_Mouse1.21449907
70LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.21444440
71SMAD3_21741376_ChIP-Seq_ESCs_Human1.21311899
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.20877902
73RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.20575210
74SOX2_22085726_ChIP-Seq_NPCs_Mouse1.20180265
75OCT4_18555785_Chip-Seq_ESCs_Mouse1.19575198
76PIAS1_25552417_ChIP-Seq_VCAP_Human1.19497642
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19327061
78PRDM14_20953172_ChIP-Seq_ESCs_Human1.18949787
79SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.18666654
80GATA3_21867929_ChIP-Seq_TH1_Mouse1.17998206
81NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17905682
82SMAD4_21741376_ChIP-Seq_HESCs_Human1.16711479
83TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16310892
84DROSHA_22980978_ChIP-Seq_HELA_Human1.15398660
85RNF2_18974828_ChIP-Seq_MESCs_Mouse1.15024711
86EZH2_18974828_ChIP-Seq_MESCs_Mouse1.15024711
87TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15004440
88GF1_26923725_Chip-Seq_HPCs_Mouse1.15000351
89ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.14977597
90OCT4_20526341_ChIP-Seq_ESCs_Human1.14953306
91RUNX2_22187159_ChIP-Seq_PCA_Human1.13647272
92FUS_26573619_Chip-Seq_HEK293_Human1.13327870
93CMYC_18555785_Chip-Seq_ESCs_Mouse1.13117479
94TDRD3_21172665_ChIP-Seq_MCF-7_Human1.12775753
95ESRRB_18555785_Chip-Seq_ESCs_Mouse1.12124845
96ERA_21632823_ChIP-Seq_H3396_Human1.12121692
97BCAT_22108803_ChIP-Seq_LS180_Human1.11916273
98SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.11700682
99P53_22387025_ChIP-Seq_ESCs_Mouse1.11397865
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.11081528
101MTF2_20144788_ChIP-Seq_MESCs_Mouse1.09879943
102CTCF_27219007_Chip-Seq_Bcells_Human1.09407934
103KLF4_18555785_Chip-Seq_ESCs_Mouse1.08903423
104P300_18555785_Chip-Seq_ESCs_Mouse1.08602018
105EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.08433971
106TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08250172
107FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07846908
108GATA3_21878914_ChIP-Seq_MCF-7_Human1.07606938
109SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.06949702
110CRX_20693478_ChIP-Seq_RETINA_Mouse1.06783852
111SUZ12_27294783_Chip-Seq_ESCs_Mouse1.06774244
112CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05835184
113SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.05702802
114VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.04944982
115EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.04527827
116AHR_22903824_ChIP-Seq_MCF-7_Human1.04231343
117SUZ12_18555785_Chip-Seq_ESCs_Mouse1.03875257
118OCT1_27270436_Chip-Seq_PROSTATE_Human1.03651644
119P53_21459846_ChIP-Seq_SAOS-2_Human1.03214919
120POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03024972
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03024972
122SPI1_26923725_Chip-Seq_HPCs_Mouse1.02504056
123OCT4_21477851_ChIP-Seq_ESCs_Mouse1.02469003
124IKZF1_21737484_ChIP-ChIP_HCT116_Human1.02406091
125AR_19668381_ChIP-Seq_PC3_Human1.02340718
126EZH2_27294783_Chip-Seq_NPCs_Mouse1.01708952
127STAT3_18555785_Chip-Seq_ESCs_Mouse1.01190671
128CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01045939
129CTCF_18555785_Chip-Seq_ESCs_Mouse1.00675651
130SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00205712
131RAD21_21589869_ChIP-Seq_MESCs_Mouse0.99679003
132PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99445408
133SOX2_21211035_ChIP-Seq_LN229_Gbm0.99401611
134RXR_22108803_ChIP-Seq_LS180_Human0.99385179
135EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.99310521
136SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99299610
137ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99241003
138REST_18959480_ChIP-ChIP_MESCs_Mouse0.98980144
139NANOG_20526341_ChIP-Seq_ESCs_Human0.98825240
140BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98739531
141MYC_19829295_ChIP-Seq_ESCs_Human0.98631839
142SOX2_18555785_Chip-Seq_ESCs_Mouse0.98058370
143SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.97348591
144MYC_27129775_Chip-Seq_CORNEA_Mouse0.97265141
145CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96218360
146MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95330322
147TAF2_19829295_ChIP-Seq_ESCs_Human0.95313788
148E2F1_18555785_Chip-Seq_ESCs_Mouse0.95297545
149NANOG_19829295_ChIP-Seq_ESCs_Human0.94933511
150SOX2_19829295_ChIP-Seq_ESCs_Human0.94933511
151SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.94667606
152RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.94158359
153EZH2_27294783_Chip-Seq_ESCs_Mouse0.93675896
154TBL1_22424771_ChIP-Seq_293T_Human0.93675874
155RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93595798
156CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.91706777
157RUNX1_27457419_Chip-Seq_LIVER_Mouse0.91704582
158PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.91597603
159RARA_24833708_ChIP-Seq_LIVER_Mouse0.91230635
160GATA1_19941827_ChIP-Seq_MEL86_Mouse0.90849876
161ESET_19884257_ChIP-Seq_ESCs_Mouse0.90359200
162PU1_27457419_Chip-Seq_LIVER_Mouse0.90301483
163TAF15_26573619_Chip-Seq_HEK293_Human0.89699628
164NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.88891195
165ELF1_20517297_ChIP-Seq_JURKAT_Human0.88248805
166SMAD1_18555785_Chip-Seq_ESCs_Mouse0.87778730
167MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.87725020
168ERG_20517297_ChIP-Seq_VCAP_Human0.87684468

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.47134785
2MP0001929_abnormal_gametogenesis4.75638056
3MP0008877_abnormal_DNA_methylation3.67287103
4MP0002653_abnormal_ependyma_morphology3.44563931
5MP0002210_abnormal_sex_determination2.93191190
6MP0002161_abnormal_fertility/fecundity2.92362544
7MP0002735_abnormal_chemical_nociception2.62453631
8MP0009046_muscle_twitch2.59402856
9MP0005623_abnormal_meninges_morphology2.56034241
10MP0001145_abnormal_male_reproductive2.51500031
11MP0005670_abnormal_white_adipose2.45038994
12MP0001485_abnormal_pinna_reflex2.23898135
13MP0000653_abnormal_sex_gland2.20886508
14MP0001348_abnormal_lacrimal_gland2.15634052
15MP0005410_abnormal_fertilization14.3863800
16MP0003646_muscle_fatigue1.87261189
17MP0006276_abnormal_autonomic_nervous1.86664905
18MP0003195_calcinosis1.82247603
19MP0001970_abnormal_pain_threshold1.69200389
20MP0004142_abnormal_muscle_tone1.67608224
21MP0001905_abnormal_dopamine_level1.67551961
22MP0004145_abnormal_muscle_electrophysio1.66492044
23MP0004859_abnormal_synaptic_plasticity1.66414917
24MP0003878_abnormal_ear_physiology1.57872380
25MP0005377_hearing/vestibular/ear_phenot1.57872380
26MP0002822_catalepsy1.55721971
27MP0005645_abnormal_hypothalamus_physiol1.48384256
28MP0001984_abnormal_olfaction1.48227793
29MP0001765_abnormal_ion_homeostasis1.43786347
30MP0001963_abnormal_hearing_physiology1.41375081
31MP0000026_abnormal_inner_ear1.39348421
32MP0006292_abnormal_olfactory_placode1.34000217
33MP0004233_abnormal_muscle_weight1.32621462
34MP0003635_abnormal_synaptic_transmissio1.28569253
35MP0002249_abnormal_larynx_morphology1.24508076
36MP0003329_amyloid_beta_deposits1.22520088
37MP0004270_analgesia1.22386127
38MP0004742_abnormal_vestibular_system1.20998360
39MP0002282_abnormal_trachea_morphology1.12873906
40MP0003119_abnormal_digestive_system1.10540920
41MP0002572_abnormal_emotion/affect_behav1.08158287
42MP0009745_abnormal_behavioral_response1.05733627
43MP0005646_abnormal_pituitary_gland1.04828990
44MP0000678_abnormal_parathyroid_gland1.04766242
45MP0003718_maternal_effect1.04302618
46MP0004085_abnormal_heartbeat1.03302010
47MP0009053_abnormal_anal_canal1.02789779
48MP0002909_abnormal_adrenal_gland1.01318929
49MP0003137_abnormal_impulse_conducting0.98398640
50MP0002063_abnormal_learning/memory/cond0.97902206
51MP0002184_abnormal_innervation0.97581282
52MP0001486_abnormal_startle_reflex0.95245401
53MP0002160_abnormal_reproductive_system0.94437455
54MP0003633_abnormal_nervous_system0.93803824
55MP0000230_abnormal_systemic_arterial0.93685789
56MP0000470_abnormal_stomach_morphology0.92792002
57MP0002064_seizures0.91113549
58MP0004043_abnormal_pH_regulation0.90664016
59MP0008995_early_reproductive_senescence0.88405736
60MP0008004_abnormal_stomach_pH0.88109396
61MP0005423_abnormal_somatic_nervous0.87669332
62MP0010386_abnormal_urinary_bladder0.87424673
63MP0002752_abnormal_somatic_nervous0.86989006
64MP0002876_abnormal_thyroid_physiology0.86494072
65MP0004885_abnormal_endolymph0.84207027
66MP0003045_fibrosis0.84065667
67MP0008961_abnormal_basal_metabolism0.81776411
68MP0001440_abnormal_grooming_behavior0.79595826
69MP0003136_yellow_coat_color0.79219478
70MP0002638_abnormal_pupillary_reflex0.78919158
71MP0002272_abnormal_nervous_system0.78064961
72MP0003632_abnormal_nervous_system0.77969988
73MP0000778_abnormal_nervous_system0.77962719
74MP0005647_abnormal_sex_gland0.77220005
75MP0000049_abnormal_middle_ear0.75122162
76MP0005448_abnormal_energy_balance0.74208220
77MP0004036_abnormal_muscle_relaxation0.73225308
78MP0004019_abnormal_vitamin_homeostasis0.72459193
79MP0005386_behavior/neurological_phenoty0.71654060
80MP0004924_abnormal_behavior0.71654060
81MP0005195_abnormal_posterior_eye0.70646014
82MP0003631_nervous_system_phenotype0.70339667
83MP0003879_abnormal_hair_cell0.70274618
84MP0001968_abnormal_touch/_nociception0.69202310
85MP0003953_abnormal_hormone_level0.68661903
86MP0003880_abnormal_central_pattern0.67318836
87MP0003183_abnormal_peptide_metabolism0.66788618
88MP0009780_abnormal_chondrocyte_physiolo0.66581702
89MP0005636_abnormal_mineral_homeostasis0.64406424
90MP0008569_lethality_at_weaning0.63105124
91MP0001502_abnormal_circadian_rhythm0.62638877
92MP0003283_abnormal_digestive_organ0.62618369
93MP0004811_abnormal_neuron_physiology0.62225715
94MP0005551_abnormal_eye_electrophysiolog0.61970350
95MP0000604_amyloidosis0.59260211
96MP0002557_abnormal_social/conspecific_i0.58312879
97MP0002736_abnormal_nociception_after0.57557711
98MP0002928_abnormal_bile_duct0.57498913
99MP0002971_abnormal_brown_adipose0.57413875
100MP0003787_abnormal_imprinting0.57387627
101MP0005253_abnormal_eye_physiology0.57312691
102MP0005360_urolithiasis0.56788126
103MP0000751_myopathy0.55131344
104MP0000569_abnormal_digit_pigmentation0.54491635
105MP0002734_abnormal_mechanical_nocicepti0.54250892
106MP0008058_abnormal_DNA_repair0.53895987
107MP0002152_abnormal_brain_morphology0.52852703
108MP0003690_abnormal_glial_cell0.52273607
109MP0002229_neurodegeneration0.51889457
110MP0005666_abnormal_adipose_tissue0.51603123
111MP0005535_abnormal_body_temperature0.51302893
112MP0003699_abnormal_female_reproductive0.50736288
113MP0004133_heterotaxia0.48975219
114MP0003115_abnormal_respiratory_system0.46741790
115MP0000955_abnormal_spinal_cord0.46394076
116MP0001501_abnormal_sleep_pattern0.46223611
117MP0003634_abnormal_glial_cell0.45965377
118MP0002067_abnormal_sensory_capabilities0.45320693
119MP0001324_abnormal_eye_pigmentation0.45207486
120MP0008875_abnormal_xenobiotic_pharmacok0.45171962
121MP0005389_reproductive_system_phenotype0.44782298
122MP0002269_muscular_atrophy0.44097311
123MP0002234_abnormal_pharynx_morphology0.43365939
124MP0002066_abnormal_motor_capabilities/c0.42218270
125MP0000013_abnormal_adipose_tissue0.41779752
126MP0002254_reproductive_system_inflammat0.40925745
127MP0003011_delayed_dark_adaptation0.40342726
128MP0004130_abnormal_muscle_cell0.39804524
129MP0002882_abnormal_neuron_morphology0.39040371
130MP0002139_abnormal_hepatobiliary_system0.38782778
131MP0002837_dystrophic_cardiac_calcinosis0.37584541
132MP0001664_abnormal_digestion0.37003790
133MP0010329_abnormal_lipoprotein_level0.36440683
134MP0009115_abnormal_fat_cell0.36421065
135MP0002733_abnormal_thermal_nociception0.36295411
136MP0000631_abnormal_neuroendocrine_gland0.36225374
137MP0006036_abnormal_mitochondrial_physio0.35551415
138MP0008872_abnormal_physiological_respon0.35175970
139MP0005167_abnormal_blood-brain_barrier0.34527444
140MP0001986_abnormal_taste_sensitivity0.34082608

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.87659432
2Abnormal respiratory motile cilium morphology (HP:0005938)7.82222347
3Abnormal respiratory epithelium morphology (HP:0012253)7.82222347
4Abnormal ciliary motility (HP:0012262)7.38605976
5Rhinitis (HP:0012384)7.14892627
6Genetic anticipation (HP:0003743)7.12125117
7Chronic bronchitis (HP:0004469)6.50884641
8Infertility (HP:0000789)6.06939156
9Nasal polyposis (HP:0100582)5.96899638
10Progressive cerebellar ataxia (HP:0002073)5.84890445
11Abnormality of the nasal mucosa (HP:0000433)4.95631914
12Male infertility (HP:0003251)4.74723537
13Severe visual impairment (HP:0001141)4.44201845
14Nephronophthisis (HP:0000090)4.39426732
15Bronchitis (HP:0012387)4.36498622
16Bronchiectasis (HP:0002110)4.22255234
17Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.96799782
18Hypoplastic ischia (HP:0003175)3.91771217
19Attenuation of retinal blood vessels (HP:0007843)3.82670102
20Gaze-evoked nystagmus (HP:0000640)3.79822690
21Abnormality of binocular vision (HP:0011514)3.75773852
22Diplopia (HP:0000651)3.75773852
23Abnormal spermatogenesis (HP:0008669)3.65033726
24Abnormality of the ischium (HP:0003174)3.50587298
25Bony spicule pigmentary retinopathy (HP:0007737)3.45979102
26Abnormality of the renal medulla (HP:0100957)3.34238364
27Hyperkalemia (HP:0002153)3.32890323
28Pancreatic cysts (HP:0001737)3.25267889
29Hyperventilation (HP:0002883)3.18896305
30Congenital stationary night blindness (HP:0007642)3.11089894
31Abnormality of midbrain morphology (HP:0002418)3.11022720
32Molar tooth sign on MRI (HP:0002419)3.11022720
33Recurrent otitis media (HP:0000403)3.09989705
34Postural instability (HP:0002172)2.97137318
35Recurrent bronchitis (HP:0002837)2.93574609
36Recurrent sinusitis (HP:0011108)2.91227300
37Tubular atrophy (HP:0000092)2.85320369
38Abnormality of the pubic bones (HP:0003172)2.82394078
39Abnormal rod and cone electroretinograms (HP:0008323)2.82230927
40Medial flaring of the eyebrow (HP:0010747)2.79691052
41True hermaphroditism (HP:0010459)2.77582496
42Decreased circulating renin level (HP:0003351)2.77377826
43Protruding tongue (HP:0010808)2.74225480
44Sclerocornea (HP:0000647)2.72097415
45Abnormality of macular pigmentation (HP:0008002)2.71261284
46Dysmetric saccades (HP:0000641)2.66545913
47Polydipsia (HP:0001959)2.62541681
48Abnormal drinking behavior (HP:0030082)2.62541681
49Tubulointerstitial abnormality (HP:0001969)2.60899736
50Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.56848353
51Tubulointerstitial nephritis (HP:0001970)2.50221602
52Azoospermia (HP:0000027)2.48952282
53Congenital sensorineural hearing impairment (HP:0008527)2.48030274
54Clumsiness (HP:0002312)2.47485037
55Tubulointerstitial fibrosis (HP:0005576)2.43303166
56Facial shape deformation (HP:0011334)2.41940661
57Potter facies (HP:0002009)2.41940661
58Truncal obesity (HP:0001956)2.36872285
59Abolished electroretinogram (ERG) (HP:0000550)2.31517897
60Abnormality of renal excretion (HP:0011036)2.21836167
61Abnormality of potassium homeostasis (HP:0011042)2.19741518
62Febrile seizures (HP:0002373)2.18188027
63Pancreatic fibrosis (HP:0100732)2.17073591
64Renovascular hypertension (HP:0100817)2.14845202
65Congenital hepatic fibrosis (HP:0002612)2.14327411
66Abnormality of saccadic eye movements (HP:0000570)2.12951572
67Inability to walk (HP:0002540)2.09233656
68Postaxial foot polydactyly (HP:0001830)2.08874770
69Cone-rod dystrophy (HP:0000548)2.08562020
70Myokymia (HP:0002411)2.04822694
71Tongue fasciculations (HP:0001308)2.04195997
72Abnormal urine output (HP:0012590)2.03659737
73Neurofibrillary tangles (HP:0002185)2.02412504
74Large for gestational age (HP:0001520)2.01521378
75Impulsivity (HP:0100710)2.01420798
76Decreased central vision (HP:0007663)2.01314049
77Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0510982
78Dynein arm defect of respiratory motile cilia (HP:0012255)11.5973979
79Absent/shortened dynein arms (HP:0200106)11.5973979
80Microglossia (HP:0000171)1.97382033
81Urinary bladder sphincter dysfunction (HP:0002839)1.97167898
82Abnormality of the diencephalon (HP:0010662)1.94891825
83Abnormality of renin-angiotensin system (HP:0000847)1.93783569
84Broad-based gait (HP:0002136)1.90950643
85Amelogenesis imperfecta (HP:0000705)1.90840740
86Macular degeneration (HP:0000608)1.90420608
87Short ribs (HP:0000773)1.90328855
88Abnormal gallbladder physiology (HP:0012438)1.90327298
89Cholecystitis (HP:0001082)1.90327298
90Increased neuronal autofluorescent lipopigment (HP:0002074)1.90072902
91Epileptic encephalopathy (HP:0200134)1.89681713
92Polyuria (HP:0000103)1.89103432
93Median cleft lip (HP:0000161)1.88541099
94Hemiparesis (HP:0001269)1.87384273
95Bile duct proliferation (HP:0001408)1.87242210
96Abnormal biliary tract physiology (HP:0012439)1.87242210
97Focal seizures (HP:0007359)1.87042161
98Pendular nystagmus (HP:0012043)1.86618580
99Abnormality of ocular smooth pursuit (HP:0000617)1.86307567
100Abnormality of the lower motor neuron (HP:0002366)1.85451849
101Anencephaly (HP:0002323)1.85357233
102Bulbous nose (HP:0000414)1.82781512
103Autoimmune thrombocytopenia (HP:0001973)1.82024010
104Type II lissencephaly (HP:0007260)1.81570508
105Stage 5 chronic kidney disease (HP:0003774)1.81130844
106Muscle fibrillation (HP:0010546)1.80944691
107Dialeptic seizures (HP:0011146)1.80441660
108Absence seizures (HP:0002121)1.80298399
109Chorioretinal atrophy (HP:0000533)1.79626624
110Cerebellar dysplasia (HP:0007033)1.79501050
111Cystic liver disease (HP:0006706)1.77218080
112Renal dysplasia (HP:0000110)1.75899261
113Abnormality of the dental root (HP:0006486)1.75291478
114Taurodontia (HP:0000679)1.75291478
115Abnormality of permanent molar morphology (HP:0011071)1.75291478
116Increased corneal curvature (HP:0100692)1.74569877
117Keratoconus (HP:0000563)1.74569877
118Postaxial hand polydactyly (HP:0001162)1.74362872
119Retinal atrophy (HP:0001105)1.74082514
120J-shaped sella turcica (HP:0002680)1.73709835
121Impaired smooth pursuit (HP:0007772)1.73445806
122Dyschromatopsia (HP:0007641)1.72023906
123Spastic tetraparesis (HP:0001285)1.71804071
124Oculomotor apraxia (HP:0000657)1.71440240
125Patellar aplasia (HP:0006443)1.70351057
126Abnormality of the renal cortex (HP:0011035)1.69932541
127Abnormality of the dental pulp (HP:0006479)1.68739975
128Prolonged QT interval (HP:0001657)1.68120530
129Facial cleft (HP:0002006)1.67303951
130Confusion (HP:0001289)1.66962559
131Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.66721512
132Cerebral inclusion bodies (HP:0100314)1.66336529
133Abnormality of the renal collecting system (HP:0004742)1.65326377
134Aplasia/Hypoplasia of the tibia (HP:0005772)1.65319956
135Abnormality of molar (HP:0011077)1.65234343
136Abnormality of molar morphology (HP:0011070)1.65234343
137Stereotypic behavior (HP:0000733)1.65087536
138Ectopic kidney (HP:0000086)1.64970166
139Deformed sella turcica (HP:0002681)1.64025166
140Gait imbalance (HP:0002141)1.64014000
141Aplasia/Hypoplasia of the tongue (HP:0010295)1.62422818
142Chronic hepatic failure (HP:0100626)1.61272651
143Absent frontal sinuses (HP:0002688)1.59895741
144Congenital primary aphakia (HP:0007707)1.59761574
145Heterotopia (HP:0002282)1.59094044
146Limb ataxia (HP:0002070)1.56513728
147Bundle branch block (HP:0011710)1.55411066
148Choroideremia (HP:0001139)1.54449448
149Exercise-induced myalgia (HP:0003738)1.54053810
150Gonadotropin excess (HP:0000837)1.53988004
151Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.51558584
152Fibular hypoplasia (HP:0003038)1.51447239
153Nephropathy (HP:0000112)1.50175659
154Asymmetric septal hypertrophy (HP:0001670)1.46828224
155Genital tract atresia (HP:0001827)1.43336712
156Chronic sinusitis (HP:0011109)1.42088175
157Short thorax (HP:0010306)1.41427633
158Optic nerve hypoplasia (HP:0000609)1.40815483
159Aplasia/Hypoplasia of the lens (HP:0008063)1.40622301
160Pachygyria (HP:0001302)1.39542762
161Nephrogenic diabetes insipidus (HP:0009806)1.37792499
162Amyotrophic lateral sclerosis (HP:0007354)1.37649814
163Bell-shaped thorax (HP:0001591)1.37614678
164Decreased electroretinogram (ERG) amplitude (HP:0000654)1.37509810
165Retinal dysplasia (HP:0007973)1.36918263

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.07924659
2PDK47.07924659
3FRK6.80746831
4PRKD35.88758914
5TESK15.40580125
6PDK24.46637037
7ICK3.60263688
8SIK23.19522276
9WNK43.14773378
10PLK43.10751972
11PTK2B3.00934308
12ACVR1B2.56739160
13BMPR1B2.55809958
14STK392.50634809
15STK382.32379962
16DDR22.29080054
17CAMK1D2.27602900
18ADRBK22.10312062
19CASK1.98909287
20PNCK1.89979918
21MAP4K21.80403306
22EPHA41.77626586
23LMTK21.73788338
24GRK11.44140693
25AKT31.43206705
26TNIK1.37467177
27PDK11.31284106
28CDK121.29665718
29TYRO31.26022866
30MUSK1.23098917
31MAP2K71.14488622
32DYRK1B1.12610437
33TNK21.09277952
34WNK11.06653577
35MAPK131.03247429
36RIPK41.02077274
37NTRK21.00580019
38ZAK0.99996595
39PDPK10.95555337
40ADRBK10.95267186
41PLK20.90846696
42PRKAA20.89416905
43PRKCE0.88855355
44TAOK30.87370245
45NEK20.86476928
46BRD40.86082654
47NTRK30.84637231
48MAP3K40.81457967
49PIK3CG0.81072396
50STK38L0.78575552
51PKN10.78221148
52MAPK150.77750010
53PINK10.76384349
54RPS6KA60.76190519
55SGK20.74973379
56TGFBR10.73144366
57CAMK40.69660448
58TLK10.69285223
59KIT0.69060186
60PRKCG0.68872402
61OBSCN0.63208994
62CAMKK10.62756877
63CAMK1G0.61846289
64MAP3K70.61539430
65PHKG20.61263867
66PHKG10.61263867
67MST1R0.60448442
68SGK10.59750448
69MKNK20.59012986
70NUAK10.58661310
71CCNB10.58574053
72MINK10.57965770
73INSRR0.55878374
74MAP3K90.55802278
75RIPK10.54591339
76NEK60.54312511
77DYRK30.51233947
78MAP2K60.49445861
79PASK0.47441880
80RPS6KA20.45618326
81EEF2K0.44046892
82CHUK0.42459650
83TTK0.41220992
84WNK30.41192833
85CHEK20.40672651
86ERBB20.40530914
87OXSR10.40412398
88IRAK10.40098375
89BRSK20.38362730
90CDK50.36880096
91BRSK10.36567176
92RPS6KA10.34793241
93MARK10.34003034
94STK110.33147563
95MAPK10.32935078
96MARK20.32930076
97PAK60.32430652
98PRKAA10.32225741
99MAPK110.31417365
100MAP2K20.31411462
101PRKCH0.31129669
102RPS6KC10.30360972
103RPS6KL10.30360972
104AKT10.29735712
105CAMK2A0.28326145
106PRKG20.28151401
107STK30.27717259
108TAOK10.27407201
109MAP3K10.26852138
110CHEK10.26068716
111NTRK10.26029266
112TRIB30.25832507
113MAP2K40.25732191
114PRKCZ0.25443246
115IRAK20.24468560
116RPS6KB10.23878777
117PAK10.22659579
118ZAP700.20810520
119DAPK20.20702881
120MAPKAPK50.20146386
121CDK150.19596766
122PRKCQ0.16692962
123CAMK10.16149469
124CDK180.16096460
125GSK3B0.15827848
126MAP3K20.15796108
127CDK11A0.14391406
128PRKCA0.14171146
129PRKACG0.13311522
130RPS6KA30.13224460
131MAPK100.13094488
132MTOR0.12656198
133CDK30.12148514
134PRKG10.11325946
135SGK2230.11086582
136SGK4940.11086582
137MAPK80.11049378
138PRKACA0.09549342
139ATM0.09428081
140PDGFRB0.09420367
141PRKCB0.09002768
142TESK20.08760786
143CDK140.08622229
144PAK20.08157525
145WEE10.07709452
146PRKD20.07660566

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.19172504
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.27589966
3Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.18060845
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.17893141
5Pyruvate metabolism_Homo sapiens_hsa006202.68192443
6Butanoate metabolism_Homo sapiens_hsa006502.48693754
7Propanoate metabolism_Homo sapiens_hsa006402.32778702
8Carbohydrate digestion and absorption_Homo sapiens_hsa049732.27140901
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.24527871
10Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.24411293
11Glucagon signaling pathway_Homo sapiens_hsa049222.18338327
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.15038099
13Phototransduction_Homo sapiens_hsa047442.11677718
14Pentose phosphate pathway_Homo sapiens_hsa000302.10164496
15Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.01209095
16Vitamin B6 metabolism_Homo sapiens_hsa007501.93424215
17Amphetamine addiction_Homo sapiens_hsa050311.92594766
18Glycerolipid metabolism_Homo sapiens_hsa005611.85924278
19Linoleic acid metabolism_Homo sapiens_hsa005911.85218750
20Serotonergic synapse_Homo sapiens_hsa047261.80181150
21Insulin secretion_Homo sapiens_hsa049111.72488077
22Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.71850925
23PPAR signaling pathway_Homo sapiens_hsa033201.70426172
24Glycerophospholipid metabolism_Homo sapiens_hsa005641.70077482
25Mineral absorption_Homo sapiens_hsa049781.69420399
26Fatty acid degradation_Homo sapiens_hsa000711.67038512
27Fatty acid metabolism_Homo sapiens_hsa012121.63573534
28Tryptophan metabolism_Homo sapiens_hsa003801.55985445
29Maturity onset diabetes of the young_Homo sapiens_hsa049501.48305724
30Fructose and mannose metabolism_Homo sapiens_hsa000511.48185264
31Renin-angiotensin system_Homo sapiens_hsa046141.48048740
32Long-term potentiation_Homo sapiens_hsa047201.42400489
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.41238818
34Renin secretion_Homo sapiens_hsa049241.40542611
35Dorso-ventral axis formation_Homo sapiens_hsa043201.39296091
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.34721003
37Primary bile acid biosynthesis_Homo sapiens_hsa001201.34320634
38Salivary secretion_Homo sapiens_hsa049701.32135933
39Fat digestion and absorption_Homo sapiens_hsa049751.31127069
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.28932714
41Synaptic vesicle cycle_Homo sapiens_hsa047211.27358127
42Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.26946787
43Carbon metabolism_Homo sapiens_hsa012001.25958726
44Oocyte meiosis_Homo sapiens_hsa041141.24676033
45Circadian entrainment_Homo sapiens_hsa047131.21573332
46Gastric acid secretion_Homo sapiens_hsa049711.21277602
47Olfactory transduction_Homo sapiens_hsa047401.21059429
48Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.20510472
49Bile secretion_Homo sapiens_hsa049761.19027323
50Taste transduction_Homo sapiens_hsa047421.16060845
51Nitrogen metabolism_Homo sapiens_hsa009101.15975868
52Cocaine addiction_Homo sapiens_hsa050301.15418310
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.14983531
54Ether lipid metabolism_Homo sapiens_hsa005651.13526415
55Basal transcription factors_Homo sapiens_hsa030221.11990637
56Caffeine metabolism_Homo sapiens_hsa002321.09557789
57Cardiac muscle contraction_Homo sapiens_hsa042601.09440844
58Nicotine addiction_Homo sapiens_hsa050331.08828489
59Thyroid hormone synthesis_Homo sapiens_hsa049181.07143501
60Calcium signaling pathway_Homo sapiens_hsa040201.06720282
61Glutamatergic synapse_Homo sapiens_hsa047241.06669677
62Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.03676925
63Biosynthesis of amino acids_Homo sapiens_hsa012301.01916869
64Pancreatic secretion_Homo sapiens_hsa049720.97836069
65Steroid hormone biosynthesis_Homo sapiens_hsa001400.97793646
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.97636183
67Retinol metabolism_Homo sapiens_hsa008300.95180461
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.94382498
69Adipocytokine signaling pathway_Homo sapiens_hsa049200.93545004
70Lysine degradation_Homo sapiens_hsa003100.93479165
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.92522269
72Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.85444195
73Selenocompound metabolism_Homo sapiens_hsa004500.83237290
74Morphine addiction_Homo sapiens_hsa050320.82856187
75Estrogen signaling pathway_Homo sapiens_hsa049150.81658189
76Long-term depression_Homo sapiens_hsa047300.81258044
77Aldosterone synthesis and secretion_Homo sapiens_hsa049250.80991385
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80149906
79Sulfur metabolism_Homo sapiens_hsa009200.79731966
80cGMP-PKG signaling pathway_Homo sapiens_hsa040220.78149675
81Collecting duct acid secretion_Homo sapiens_hsa049660.77199646
82ABC transporters_Homo sapiens_hsa020100.76873266
83cAMP signaling pathway_Homo sapiens_hsa040240.76716405
84Chemical carcinogenesis_Homo sapiens_hsa052040.72319128
85Protein digestion and absorption_Homo sapiens_hsa049740.69565143
86Dopaminergic synapse_Homo sapiens_hsa047280.69119633
87Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.67757271
88Ovarian steroidogenesis_Homo sapiens_hsa049130.66974777
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66043740
90Histidine metabolism_Homo sapiens_hsa003400.62909505
91Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60905443
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.59969210
93GABAergic synapse_Homo sapiens_hsa047270.59747051
94Huntingtons disease_Homo sapiens_hsa050160.57749842
95Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56384050
96Hedgehog signaling pathway_Homo sapiens_hsa043400.56128167
97MAPK signaling pathway_Homo sapiens_hsa040100.54111511
98Vascular smooth muscle contraction_Homo sapiens_hsa042700.53947784
99Type II diabetes mellitus_Homo sapiens_hsa049300.52055986
100Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48748725
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47002805
102Endocytosis_Homo sapiens_hsa041440.46389406
103Purine metabolism_Homo sapiens_hsa002300.46092390
104Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.45929860
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.45821555
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.45373896
107AMPK signaling pathway_Homo sapiens_hsa041520.45137381
108beta-Alanine metabolism_Homo sapiens_hsa004100.44939185
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.43940898
110Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43232311
111Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42342791
112Cyanoamino acid metabolism_Homo sapiens_hsa004600.40911362
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38522803
114Inositol phosphate metabolism_Homo sapiens_hsa005620.38382948
115Arginine and proline metabolism_Homo sapiens_hsa003300.37725784
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37526156
117Type I diabetes mellitus_Homo sapiens_hsa049400.36833509
118Glutathione metabolism_Homo sapiens_hsa004800.34443872
119Dilated cardiomyopathy_Homo sapiens_hsa054140.33834604
120Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.33558073
121Graft-versus-host disease_Homo sapiens_hsa053320.32835362
122Oxytocin signaling pathway_Homo sapiens_hsa049210.32805719
123Fanconi anemia pathway_Homo sapiens_hsa034600.32674056
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32307032
125Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.32155205
126Cholinergic synapse_Homo sapiens_hsa047250.31976312
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31974321
128Homologous recombination_Homo sapiens_hsa034400.31330709
129Peroxisome_Homo sapiens_hsa041460.29355640
130Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.28092372
131Basal cell carcinoma_Homo sapiens_hsa052170.26909101
132Arachidonic acid metabolism_Homo sapiens_hsa005900.26896300
133Central carbon metabolism in cancer_Homo sapiens_hsa052300.26626787
134Vitamin digestion and absorption_Homo sapiens_hsa049770.26610034
135Choline metabolism in cancer_Homo sapiens_hsa052310.26404704
136Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.26107539
137Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25483664
138Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.25212286
139mRNA surveillance pathway_Homo sapiens_hsa030150.24432175

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