MORN5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule catabolic process (GO:0016998)9.67338530
2cell wall macromolecule metabolic process (GO:0044036)9.67338530
3sperm-egg recognition (GO:0035036)9.45807691
4multicellular organism reproduction (GO:0032504)9.23712802
5acrosome reaction (GO:0007340)8.70560927
6regulation of cilium movement (GO:0003352)8.63660229
7ventricular system development (GO:0021591)8.60439409
8binding of sperm to zona pellucida (GO:0007339)8.51552930
9cell-cell recognition (GO:0009988)8.45910689
10axoneme assembly (GO:0035082)8.44920427
11spermatid development (GO:0007286)8.21055532
12plasma membrane fusion (GO:0045026)8.19098982
13reproduction (GO:0000003)7.58200061
14piRNA metabolic process (GO:0034587)7.52410006
15male meiosis (GO:0007140)7.43860223
16negative regulation of inclusion body assembly (GO:0090084)6.98187612
17synaptonemal complex organization (GO:0070193)6.88810656
18single fertilization (GO:0007338)6.75760680
19primary alcohol catabolic process (GO:0034310)6.52613559
20sperm capacitation (GO:0048240)6.49467416
21nucleoside diphosphate phosphorylation (GO:0006165)6.32858259
22synaptonemal complex assembly (GO:0007130)6.23013995
23vitamin transmembrane transport (GO:0035461)5.86296331
24fertilization (GO:0009566)5.70012861
25regulation of inclusion body assembly (GO:0090083)5.66099873
26ethanol metabolic process (GO:0006067)5.60260038
27GTP biosynthetic process (GO:0006183)5.58783495
28male meiosis I (GO:0007141)5.51967783
29spermatid nucleus differentiation (GO:0007289)5.47136035
30left/right axis specification (GO:0070986)5.45743247
31diterpenoid biosynthetic process (GO:0016102)5.43601141
32spermatogenesis (GO:0007283)5.36672966
33regulation of microtubule-based movement (GO:0060632)5.34657002
34male gamete generation (GO:0048232)5.34433861
35intraciliary transport (GO:0042073)5.29019091
36one-carbon compound transport (GO:0019755)5.06351096
37UTP biosynthetic process (GO:0006228)4.96073013
38gamete generation (GO:0007276)4.93687261
39microtubule severing (GO:0051013)4.85248598
40DNA methylation involved in gamete generation (GO:0043046)4.76658319
41cilium organization (GO:0044782)4.75849271
42pyrimidine-containing compound transmembrane transport (GO:0072531)4.70761030
43lung epithelium development (GO:0060428)4.68637403
44tolerance induction (GO:0002507)4.67427493
45organic cation transport (GO:0015695)4.65688595
46germ cell development (GO:0007281)4.61670106
47cellular process involved in reproduction in multicellular organism (GO:0022412)4.58669581
48UTP metabolic process (GO:0046051)4.50272291
49protein polyglutamylation (GO:0018095)4.43053334
50microtubule-based movement (GO:0007018)4.43050064
51cilium assembly (GO:0042384)4.41866497
52ethanol oxidation (GO:0006069)4.39016455
53chromosome organization involved in meiosis (GO:0070192)4.35947182
54meiosis I (GO:0007127)4.32533244
55negative regulation of T cell differentiation in thymus (GO:0033085)4.29295873
56cell recognition (GO:0008037)4.27873868
57meiotic nuclear division (GO:0007126)4.21579884
58cellular component assembly involved in morphogenesis (GO:0010927)4.17914525
59negative regulation of immunoglobulin mediated immune response (GO:0002890)4.16921199
60negative regulation of B cell mediated immunity (GO:0002713)4.16921199
61glomerular epithelial cell development (GO:0072310)4.11656774
62protein localization to cilium (GO:0061512)4.06898471
63left/right pattern formation (GO:0060972)4.05420948
64calcium ion-dependent exocytosis (GO:0017156)4.04710422
65meiotic cell cycle (GO:0051321)4.03488262
66establishment of apical/basal cell polarity (GO:0035089)4.03307327
67microtubule bundle formation (GO:0001578)4.01821827
68response to xenobiotic stimulus (GO:0009410)3.98601623
69retinoic acid metabolic process (GO:0042573)3.94140883
70cilium morphogenesis (GO:0060271)3.92495976
71microtubule depolymerization (GO:0007019)3.90179343
72multicellular organismal reproductive process (GO:0048609)3.88147633
73guanosine-containing compound biosynthetic process (GO:1901070)3.82250611
74protein refolding (GO:0042026)3.80802908
75terpenoid biosynthetic process (GO:0016114)3.78893016
76regulation of interleukin-5 production (GO:0032674)3.75199824
77negative regulation of humoral immune response (GO:0002921)3.69733974
78positive regulation of tolerance induction (GO:0002645)3.69561729
79negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.61696253
80establishment of monopolar cell polarity (GO:0061162)3.60817604
81establishment or maintenance of monopolar cell polarity (GO:0061339)3.60817604
82CTP metabolic process (GO:0046036)3.60430767
83CTP biosynthetic process (GO:0006241)3.60430767
84establishment of tissue polarity (GO:0007164)3.54309640
85establishment of planar polarity (GO:0001736)3.54309640
86nucleotide phosphorylation (GO:0046939)3.48743483
87regulation of germinal center formation (GO:0002634)3.44129375
88cytoplasmic microtubule organization (GO:0031122)3.39167858
89smoothened signaling pathway (GO:0007224)3.29301264
90retinal rod cell development (GO:0046548)3.28967448
91pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.27666596
92seminiferous tubule development (GO:0072520)3.25545403
93glutathione derivative metabolic process (GO:1901685)3.23102673
94glutathione derivative biosynthetic process (GO:1901687)3.23102673
95nucleoside diphosphate metabolic process (GO:0009132)3.18374463
96pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.17990440
97retinol metabolic process (GO:0042572)3.17224109
98regulation of interleukin-13 production (GO:0032656)3.15778467
99lateral sprouting from an epithelium (GO:0060601)3.15747959
100primary alcohol metabolic process (GO:0034308)3.13619469
101centriole assembly (GO:0098534)3.11339981
102chaperone-mediated protein complex assembly (GO:0051131)3.10598628
103phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.10370043
104exogenous drug catabolic process (GO:0042738)3.10236760
105microtubule polymerization or depolymerization (GO:0031109)3.07913889
106genitalia morphogenesis (GO:0035112)3.05828568
107pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.03841455
108lateral ventricle development (GO:0021670)3.02435006
109cell projection assembly (GO:0030031)3.02163869
110centriole replication (GO:0007099)3.01215679
111positive regulation of smoothened signaling pathway (GO:0045880)2.99855463
112multicellular organismal development (GO:0007275)2.97858730
113carnitine metabolic process (GO:0009437)2.92747403
114deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.83891512
115glycerol ether metabolic process (GO:0006662)2.77168117
116apical protein localization (GO:0045176)2.76992144
117nonmotile primary cilium assembly (GO:0035058)2.76641041
118hydrogen peroxide biosynthetic process (GO:0050665)2.76640926
119negative regulation of organelle assembly (GO:1902116)2.75918893
120pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.73794292
121determination of left/right symmetry (GO:0007368)2.72711224
122synapsis (GO:0007129)2.72028268
123O-glycan processing (GO:0016266)2.68082364
124regulation of autophagic vacuole assembly (GO:2000785)2.67874954
125regulation of tolerance induction (GO:0002643)2.67267959
126regulation of centriole replication (GO:0046599)2.65769066
127multicellular organismal water homeostasis (GO:0050891)2.64643287
128determination of bilateral symmetry (GO:0009855)2.62369360
129carnitine transport (GO:0015879)2.59019950
130amino-acid betaine transport (GO:0015838)2.59019950
131regulation of microtubule depolymerization (GO:0031114)2.57561867
132ether metabolic process (GO:0018904)2.57514138
133carnitine transmembrane transport (GO:1902603)2.57344175
134ADP metabolic process (GO:0046031)2.56221170
135specification of symmetry (GO:0009799)2.55836586
136chromosome condensation (GO:0030261)2.55496269
137meiotic cell cycle process (GO:1903046)2.53077464
138intra-S DNA damage checkpoint (GO:0031573)2.52809017
139asymmetric protein localization (GO:0008105)2.52764260
140phosphatidylcholine biosynthetic process (GO:0006656)2.50800360
141establishment of nucleus localization (GO:0040023)2.50761914
142aldehyde catabolic process (GO:0046185)2.49887718
143cellular response to gamma radiation (GO:0071480)2.49276074
144organelle assembly (GO:0070925)2.47641704
145hydrogen peroxide catabolic process (GO:0042744)2.46409221
146microtubule-based process (GO:0007017)2.45423781
147reactive oxygen species biosynthetic process (GO:1903409)2.44785516
148oligosaccharide biosynthetic process (GO:0009312)2.39137932
149sodium ion homeostasis (GO:0055078)2.38651081
150heart looping (GO:0001947)2.36995430
151regulation of collateral sprouting (GO:0048670)2.35854570
152regulation of smoothened signaling pathway (GO:0008589)2.35109219
153regulation of vacuole organization (GO:0044088)2.34933220
154excretion (GO:0007588)2.34360993
155water homeostasis (GO:0030104)2.31502986
156drug catabolic process (GO:0042737)2.30846515
157cilium or flagellum-dependent cell motility (GO:0001539)16.0116995
158axonemal dynein complex assembly (GO:0070286)14.5363738
159cilium movement (GO:0003341)13.9091668
160epithelial cilium movement (GO:0003351)12.2669494
161fusion of sperm to egg plasma membrane (GO:0007342)10.7599755
162sperm motility (GO:0030317)10.5510940
163acrosome assembly (GO:0001675)10.5449967
164motile cilium assembly (GO:0044458)10.1698493
165epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.0704780

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse7.71432107
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.19735997
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.50038598
4EZH2_22144423_ChIP-Seq_EOC_Human4.15335311
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.58648261
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.26001647
7DROSHA_22980978_ChIP-Seq_HELA_Human3.23730782
8FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.95767854
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.67797470
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.65638084
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.39338655
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.38575501
13VDR_22108803_ChIP-Seq_LS180_Human2.35003083
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.25365252
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.24702669
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.22440369
17EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.13560537
18PIAS1_25552417_ChIP-Seq_VCAP_Human2.10713356
19PCGF2_27294783_Chip-Seq_ESCs_Mouse2.04958707
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02725440
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.01388918
22ESR1_20079471_ChIP-ChIP_T-47D_Human2.00666770
23RBPJ_22232070_ChIP-Seq_NCS_Mouse1.88207307
24AHR_22903824_ChIP-Seq_MCF-7_Human1.80325540
25TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.80247339
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.78966912
27RNF2_27304074_Chip-Seq_NSC_Mouse1.73930580
28NR3C1_21868756_ChIP-Seq_MCF10A_Human1.71428715
29ELK4_26923725_Chip-Seq_MESODERM_Mouse1.71214957
30KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.64888349
31FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.63812555
32ARNT_22903824_ChIP-Seq_MCF-7_Human1.62728490
33TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.61264155
34ZNF274_21170338_ChIP-Seq_K562_Hela1.60187701
35FOXM1_26456572_ChIP-Seq_MCF-7_Human1.60168928
36* RUNX1_27514584_Chip-Seq_MCF-7_Human1.56696753
37IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.55713721
38CBP_20019798_ChIP-Seq_JUKART_Human1.55713721
39RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.54935924
40ESR2_21235772_ChIP-Seq_MCF-7_Human1.54842395
41STAT1_17558387_ChIP-Seq_HELA_Human1.53610729
42KAP1_22055183_ChIP-Seq_ESCs_Mouse1.53492874
43CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52882414
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.51081037
45FLI1_21867929_ChIP-Seq_TH2_Mouse1.50191901
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.48375597
47PCGF2_27294783_Chip-Seq_NPCs_Mouse1.47831288
48SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47800640
49SMC4_20622854_ChIP-Seq_HELA_Human1.47795462
50TAL1_26923725_Chip-Seq_HPCs_Mouse1.47636181
51ESR1_21235772_ChIP-Seq_MCF-7_Human1.47373853
52NFE2_27457419_Chip-Seq_LIVER_Mouse1.47130352
53STAT6_21828071_ChIP-Seq_BEAS2B_Human1.46951940
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.46807273
55TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.46735523
56STAT1_20625510_ChIP-Seq_HELA_Human1.45763178
57* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.45687621
58WDR5_24793694_ChIP-Seq_LNCAP_Human1.45617559
59TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44452644
60TP63_23658742_ChIP-Seq_EP156T_Human1.43886818
61TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41835348
62POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.41835348
63TP53_18474530_ChIP-ChIP_U2OS_Human1.37913927
64GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.37839040
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.36661436
66MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36292997
67EZH2_27294783_Chip-Seq_ESCs_Mouse1.35276555
68CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.35074914
69KDM2B_26808549_Chip-Seq_REH_Human1.35000335
70CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.34374063
71ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33909954
72EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.33150593
73AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.29919135
74AR_21572438_ChIP-Seq_LNCaP_Human1.29652115
75SOX2_27498859_Chip-Seq_STOMACH_Mouse1.29339260
76CTNNB1_20460455_ChIP-Seq_HCT116_Human1.28763144
77SOX2_22085726_ChIP-Seq_NPCs_Mouse1.28196641
78TP63_22573176_ChIP-Seq_HFKS_Human1.27533304
79CDX2_20551321_ChIP-Seq_CACO-2_Human1.26619594
80NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.26360665
81GF1_26923725_Chip-Seq_HPCs_Mouse1.25959412
82ETV1_20927104_ChIP-Seq_GIST48_Human1.25387965
83PHF8_20622853_ChIP-Seq_HELA_Human1.24957745
84REST_21632747_ChIP-Seq_MESCs_Mouse1.24439115
85CRX_20693478_ChIP-Seq_RETINA_Mouse1.23557817
86KLF5_25053715_ChIP-Seq_YYC3_Human1.23090744
87RAD21_21589869_ChIP-Seq_MESCs_Mouse1.23003902
88OCT4_18555785_Chip-Seq_ESCs_Mouse1.22302095
89ER_23166858_ChIP-Seq_MCF-7_Human1.21613924
90SOX2_20726797_ChIP-Seq_SW620_Human1.20241399
91PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19513518
92GATA3_21867929_ChIP-Seq_CD8_Mouse1.18861637
93HNFA_21074721_ChIP-Seq_CACO-2_Human1.18740619
94PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.18343377
95FOXA1_25552417_ChIP-Seq_VCAP_Human1.18287185
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18096452
97P53_22387025_ChIP-Seq_ESCs_Mouse1.17891049
98PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.16329662
99SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15927533
100CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.14999977
101LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.14678746
102SOX9_24532713_ChIP-Seq_HFSC_Mouse1.14000985
103* SMAD4_21799915_ChIP-Seq_A2780_Human1.13807674
104TBL1_22424771_ChIP-Seq_293T_Human1.13737576
105P300_18555785_Chip-Seq_ESCs_Mouse1.13471186
106TDRD3_21172665_ChIP-Seq_MCF-7_Human1.12505255
107CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.12292077
108KLF4_18555785_Chip-Seq_ESCs_Mouse1.11581769
109CMYC_18555785_Chip-Seq_ESCs_Mouse1.11402872
110ESRRB_18555785_Chip-Seq_ESCs_Mouse1.11307722
111EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.11202197
112ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11126032
113OCT4_21477851_ChIP-Seq_ESCs_Mouse1.10995139
114CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.10982463
115CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10546400
116MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09833515
117TAF15_26573619_Chip-Seq_HEK293_Human1.09831201
118EZH2_27294783_Chip-Seq_NPCs_Mouse1.09222469
119* SMRT_27268052_Chip-Seq_Bcells_Human1.08995110
120SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08676771
121* STAT3_18555785_Chip-Seq_ESCs_Mouse1.07102864
122CTCF_27219007_Chip-Seq_Bcells_Human1.07022626
123CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.04963301
124P53_21459846_ChIP-Seq_SAOS-2_Human1.04614356
125CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03576149
126GF1B_26923725_Chip-Seq_HPCs_Mouse1.03474115
127NFYB_21822215_ChIP-Seq_K562_Human1.02953467
128P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02718949
129SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.02049011
130GATA3_21867929_ChIP-Seq_TH1_Mouse1.01942949
131NFYA_21822215_ChIP-Seq_K562_Human1.01917300
132FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01801644
133CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.01423992
134SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.01411265
135MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00616821
136CTBP1_25329375_ChIP-Seq_LNCAP_Human1.00570271
137SMAD3_21741376_ChIP-Seq_EPCs_Human1.00544420
138E2F1_18555785_Chip-Seq_ESCs_Mouse1.00538479
139RUNX1_27457419_Chip-Seq_LIVER_Mouse0.99306353
140SMAD4_21741376_ChIP-Seq_EPCs_Human0.99279727
141BCAT_22108803_ChIP-Seq_LS180_Human0.99184884
142YY1_22570637_ChIP-Seq_MALME-3M_Human0.98870405
143SMAD3_21741376_ChIP-Seq_HESCs_Human0.98821094
144TCF4_22108803_ChIP-Seq_LS180_Human0.98728808
145SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.98217493
146* SOX2_18555785_Chip-Seq_ESCs_Mouse0.98093537
147PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97065379
148CBX2_22325352_ChIP-Seq_293T-Rex_Human0.96648578
149RBPJ_21746931_ChIP-Seq_IB4_Human0.96644693
150GATA6_21074721_ChIP-Seq_CACO-2_Human0.96168397
151ZFX_18555785_Chip-Seq_ESCs_Mouse0.96103568
152FOXA1_27270436_Chip-Seq_PROSTATE_Human0.95770201
153FOXA1_25329375_ChIP-Seq_VCAP_Human0.95770201
154POU3F2_20337985_ChIP-ChIP_501MEL_Human0.95170101
155TCF4_23295773_ChIP-Seq_U87_Human0.94814672
156JARID2_20075857_ChIP-Seq_MESCs_Mouse0.94661738
157EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94640835
158BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94208400
159CTCF_18555785_Chip-Seq_ESCs_Mouse0.94085225
160SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.93532469
161GATA1_19941826_ChIP-Seq_K562_Human0.93183745
162SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.93166080
163RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.92317722
164ERG_20517297_ChIP-Seq_VCAP_Human0.92115741
165STAT3_23295773_ChIP-Seq_U87_Human0.91720562
166GATA4_25053715_ChIP-Seq_YYC3_Human0.91457407
167SUZ12_27294783_Chip-Seq_ESCs_Mouse0.91304182
168* PU1_27457419_Chip-Seq_LIVER_Mouse0.91178093
169LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91093644
170GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.89925238
171EED_16625203_ChIP-ChIP_MESCs_Mouse0.88259602
172STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.87907643
173RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.87770741
174CTCF_20526341_ChIP-Seq_ESCs_Human0.87537740
175ELF1_20517297_ChIP-Seq_JURKAT_Human0.87106638
176SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.86839282
177CBP_21632823_ChIP-Seq_H3396_Human0.86467211
178CEBPB_22108803_ChIP-Seq_LS180_Human0.86018367
179GATA3_24758297_ChIP-Seq_MCF-7_Human0.85320301
180SOX2_21211035_ChIP-Seq_LN229_Human0.84430091
181PPAR_26484153_Chip-Seq_NCI-H1993_Human0.84302276

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.49770578
2MP0001929_abnormal_gametogenesis4.98291367
3MP0002653_abnormal_ependyma_morphology4.51484700
4MP0008877_abnormal_DNA_methylation4.47187366
5MP0002132_abnormal_respiratory_system4.01657554
6MP0004043_abnormal_pH_regulation3.60745584
7MP0002277_abnormal_respiratory_mucosa3.56287843
8MP0005623_abnormal_meninges_morphology3.53407482
9MP0002210_abnormal_sex_determination3.37799729
10MP0008789_abnormal_olfactory_epithelium3.13216955
11MP0000566_synostosis3.10107242
12MP0003136_yellow_coat_color3.09580032
13MP0002161_abnormal_fertility/fecundity2.92733884
14MP0001145_abnormal_male_reproductive2.79913380
15MP0009780_abnormal_chondrocyte_physiolo2.74846530
16MP0002160_abnormal_reproductive_system2.53274252
17MP0000653_abnormal_sex_gland2.47116155
18MP0000383_abnormal_hair_follicle2.25661027
19MP0009046_muscle_twitch2.19864141
20MP0005394_taste/olfaction_phenotype2.17331603
21MP0005499_abnormal_olfactory_system2.17331603
22MP0001984_abnormal_olfaction2.16198174
23MP0002638_abnormal_pupillary_reflex2.15452607
24MP0005410_abnormal_fertilization13.2821030
25MP0004133_heterotaxia1.81650878
26MP0010678_abnormal_skin_adnexa1.75517547
27MP0002282_abnormal_trachea_morphology1.74851626
28MP0002822_catalepsy1.73852592
29MP0001485_abnormal_pinna_reflex1.65501706
30MP0009379_abnormal_foot_pigmentation1.59355836
31MP0001346_abnormal_lacrimal_gland1.59046801
32MP0003950_abnormal_plasma_membrane1.50345775
33MP0003656_abnormal_erythrocyte_physiolo1.39444272
34MP0010030_abnormal_orbit_morphology1.38192301
35MP0005083_abnormal_biliary_tract1.37865390
36MP0003646_muscle_fatigue1.34097849
37MP0005389_reproductive_system_phenotype1.32151022
38MP0008995_early_reproductive_senescence1.31127507
39MP0000026_abnormal_inner_ear1.30627481
40MP0005670_abnormal_white_adipose1.25426387
41MP0002168_other_aberrant_phenotype1.22416306
42MP0001986_abnormal_taste_sensitivity1.20762066
43MP0002233_abnormal_nose_morphology1.20380713
44MP0001765_abnormal_ion_homeostasis1.17236266
45MP0003880_abnormal_central_pattern1.16697168
46MP0008057_abnormal_DNA_replication1.12072849
47MP0002735_abnormal_chemical_nociception1.01670326
48MP0005646_abnormal_pituitary_gland0.98818434
49MP0002928_abnormal_bile_duct0.98700032
50MP0008004_abnormal_stomach_pH0.95885836
51MP0000467_abnormal_esophagus_morphology0.95174596
52MP0005423_abnormal_somatic_nervous0.94751983
53MP0005551_abnormal_eye_electrophysiolog0.92550036
54MP0001440_abnormal_grooming_behavior0.91029694
55MP0004885_abnormal_endolymph0.89401632
56MP0001502_abnormal_circadian_rhythm0.88689078
57MP0004233_abnormal_muscle_weight0.86277285
58MP0004858_abnormal_nervous_system0.86141894
59MP0002876_abnormal_thyroid_physiology0.85104258
60MP0005248_abnormal_Harderian_gland0.84430641
61MP0000678_abnormal_parathyroid_gland0.83330208
62MP0003879_abnormal_hair_cell0.82842371
63MP0001963_abnormal_hearing_physiology0.82416994
64MP0005165_increased_susceptibility_to0.82354511
65MP0003011_delayed_dark_adaptation0.82000496
66MP0000955_abnormal_spinal_cord0.79663656
67MP0005365_abnormal_bile_salt0.78828528
68MP0005647_abnormal_sex_gland0.78321564
69MP0000465_gastrointestinal_hemorrhage0.78034251
70MP0003634_abnormal_glial_cell0.77427395
71MP0005085_abnormal_gallbladder_physiolo0.75790063
72MP0005395_other_phenotype0.74033715
73MP0001970_abnormal_pain_threshold0.69439140
74MP0001968_abnormal_touch/_nociception0.69043376
75MP0005391_vision/eye_phenotype0.68873705
76MP0005503_abnormal_tendon_morphology0.67701431
77MP0002234_abnormal_pharynx_morphology0.67376832
78MP0003786_premature_aging0.66149467
79MP0003942_abnormal_urinary_system0.65262515
80MP0004883_abnormal_blood_vessel0.64690176
81MP0005253_abnormal_eye_physiology0.64535842
82MP0002133_abnormal_respiratory_system0.64175508
83MP0005388_respiratory_system_phenotype0.64175508
84MP0005377_hearing/vestibular/ear_phenot0.63942789
85MP0003878_abnormal_ear_physiology0.63942789
86MP0002098_abnormal_vibrissa_morphology0.63576617
87MP0002152_abnormal_brain_morphology0.61436000
88MP0001529_abnormal_vocalization0.61258287
89MP0003943_abnormal_hepatobiliary_system0.61082429
90MP0005636_abnormal_mineral_homeostasis0.60807721
91MP0002249_abnormal_larynx_morphology0.60398163
92MP0000778_abnormal_nervous_system0.59961946
93MP0004145_abnormal_muscle_electrophysio0.59369549
94MP0002092_abnormal_eye_morphology0.59150473
95MP0002736_abnormal_nociception_after0.58976008
96MP0001851_eye_inflammation0.58191054
97MP0008058_abnormal_DNA_repair0.57683895
98MP0005164_abnormal_response_to0.57503910
99MP0003861_abnormal_nervous_system0.57376908
100MP0002064_seizures0.56640929
101MP0002572_abnormal_emotion/affect_behav0.56466502
102MP0003690_abnormal_glial_cell0.55653128
103MP0009765_abnormal_xenobiotic_induced0.55576825
104MP0009703_decreased_birth_body0.55108833
105MP0002896_abnormal_bone_mineralization0.54776108
106MP0002136_abnormal_kidney_physiology0.54714798
107MP0009745_abnormal_behavioral_response0.53895336
108MP0005408_hypopigmentation0.53391733
109MP0001324_abnormal_eye_pigmentation0.53373188
110MP0003283_abnormal_digestive_organ0.53192883
111MP0009643_abnormal_urine_homeostasis0.50640740
112MP0000762_abnormal_tongue_morphology0.50137912
113MP0001663_abnormal_digestive_system0.49712150
114MP0010155_abnormal_intestine_physiology0.49638552
115MP0001293_anophthalmia0.49588540
116MP0005220_abnormal_exocrine_pancreas0.49075553
117MP0006072_abnormal_retinal_apoptosis0.48944596
118MP0001299_abnormal_eye_distance/0.48923447
119MP0000534_abnormal_ureter_morphology0.48105067
120MP0002557_abnormal_social/conspecific_i0.47734472
121MP0003937_abnormal_limbs/digits/tail_de0.47341614
122MP0002272_abnormal_nervous_system0.47285453
123MP0004270_analgesia0.46931985
124MP0002405_respiratory_system_inflammati0.46923967
125MP0004036_abnormal_muscle_relaxation0.46429279
126MP0004134_abnormal_chest_morphology0.45847480
127MP0003329_amyloid_beta_deposits0.45826462
128MP0000428_abnormal_craniofacial_morphol0.45437910
129MP0004381_abnormal_hair_follicle0.44627716
130MP0001270_distended_abdomen0.44334885
131MP0004019_abnormal_vitamin_homeostasis0.44306855
132MP0002909_abnormal_adrenal_gland0.43333424
133MP0005195_abnormal_posterior_eye0.42071236
134MP0008875_abnormal_xenobiotic_pharmacok0.41611534
135MP0003633_abnormal_nervous_system0.40950668
136MP0009250_abnormal_appendicular_skeleto0.40923786
137MP0003115_abnormal_respiratory_system0.40040743
138MP0003635_abnormal_synaptic_transmissio0.39819984
139MP0002102_abnormal_ear_morphology0.37771172
140MP0002734_abnormal_mechanical_nocicepti0.37699610
141MP0000432_abnormal_head_morphology0.37450649
142MP0003699_abnormal_female_reproductive0.36421162
143MP0000049_abnormal_middle_ear0.34595355
144MP0003938_abnormal_ear_development0.33354519
145MP0002063_abnormal_learning/memory/cond0.33287522
146MP0001545_abnormal_hematopoietic_system0.32924595
147MP0005397_hematopoietic_system_phenotyp0.32924595
148MP0002752_abnormal_somatic_nervous0.32662443
149MP0001727_abnormal_embryo_implantation0.32282494
150MP0000631_abnormal_neuroendocrine_gland0.31113555
151MP0001486_abnormal_startle_reflex0.30846823
152MP0002295_abnormal_pulmonary_circulatio0.30514042
153MP0001119_abnormal_female_reproductive0.30469990
154MP0002882_abnormal_neuron_morphology0.30458605
155MP0009115_abnormal_fat_cell0.30387446
156MP0002116_abnormal_craniofacial_bone0.30335220

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.46125164
2Abnormal respiratory epithelium morphology (HP:0012253)9.46125164
3Chronic bronchitis (HP:0004469)7.66685332
4Bronchiectasis (HP:0002110)5.77260739
5Nasal polyposis (HP:0100582)5.75803825
6Infertility (HP:0000789)5.07483278
7Abnormality of the nasal mucosa (HP:0000433)4.70787273
8Bronchitis (HP:0012387)4.39057574
9Nephronophthisis (HP:0000090)3.86443920
10Recurrent sinusitis (HP:0011108)3.73930074
11Pancreatic fibrosis (HP:0100732)3.41214946
12Recurrent otitis media (HP:0000403)3.16557069
13Abnormality of midbrain morphology (HP:0002418)3.12260061
14Molar tooth sign on MRI (HP:0002419)3.12260061
15Median cleft lip (HP:0000161)3.06695118
16Chronic sinusitis (HP:0011109)3.02623681
17Medial flaring of the eyebrow (HP:0010747)2.99550438
18Chronic otitis media (HP:0000389)2.91955067
19Abnormality of the renal medulla (HP:0100957)2.89590722
20Supernumerary spleens (HP:0009799)2.88786301
21Hyperactive renin-angiotensin system (HP:0000841)2.73032573
22Male infertility (HP:0003251)2.59110001
23Congenital hepatic fibrosis (HP:0002612)2.57010922
24True hermaphroditism (HP:0010459)2.55615104
25Postaxial foot polydactyly (HP:0001830)2.49783516
26Tubulointerstitial nephritis (HP:0001970)2.41129418
27Fibular hypoplasia (HP:0003038)2.37105554
28Facial cleft (HP:0002006)2.36042822
29Recurrent bronchitis (HP:0002837)2.20639068
30Gait imbalance (HP:0002141)2.18033488
31Congenital primary aphakia (HP:0007707)2.17287984
32Tubular atrophy (HP:0000092)2.09489435
33Abnormality of dentin (HP:0010299)2.07246927
34Respiratory insufficiency due to defective ciliary clearance (HP:0200073)14.3680533
35Abnormal respiratory motile cilium physiology (HP:0012261)12.1242716
36Abnormal ciliary motility (HP:0012262)10.9322331
37Dynein arm defect of respiratory motile cilia (HP:0012255)10.5557700
38Absent/shortened dynein arms (HP:0200106)10.5557700
39Rhinitis (HP:0012384)10.0149483
40Aplasia/Hypoplasia of the tongue (HP:0010295)1.98904165
41Dyschromatopsia (HP:0007641)1.95671471
42Postaxial hand polydactyly (HP:0001162)1.94694071
43Abnormal spermatogenesis (HP:0008669)1.93278947
44Occipital encephalocele (HP:0002085)1.93097779
45Genital tract atresia (HP:0001827)1.92413777
46Tubulointerstitial abnormality (HP:0001969)1.91244494
47Chronic hepatic failure (HP:0100626)1.88981050
48Nephrogenic diabetes insipidus (HP:0009806)1.88237244
49Oculomotor apraxia (HP:0000657)1.87366004
50Stage 5 chronic kidney disease (HP:0003774)1.86185768
51Furrowed tongue (HP:0000221)1.85443414
52Cystic liver disease (HP:0006706)1.84162022
53Taurodontia (HP:0000679)1.81543801
54Abnormality of permanent molar morphology (HP:0011071)1.81543801
55Abnormality of the dental root (HP:0006486)1.81543801
56Pancreatic cysts (HP:0001737)1.76856140
57Short ribs (HP:0000773)1.76750403
58Decreased circulating renin level (HP:0003351)1.75523443
59Renal salt wasting (HP:0000127)1.70704742
60Abnormal biliary tract physiology (HP:0012439)1.70036519
61Bile duct proliferation (HP:0001408)1.70036519
62Vaginal atresia (HP:0000148)1.68993997
63Central scotoma (HP:0000603)1.67306841
64Abnormality of molar (HP:0011077)1.67272696
65Abnormality of molar morphology (HP:0011070)1.67272696
66Abnormality of the dental pulp (HP:0006479)1.66745027
67Microglossia (HP:0000171)1.66324071
68Poor coordination (HP:0002370)1.60732089
69Asplenia (HP:0001746)1.58248655
70Azoospermia (HP:0000027)1.57739080
71Aplasia/Hypoplasia of the spleen (HP:0010451)1.57229189
72Absent frontal sinuses (HP:0002688)1.56694862
73Abnormal drinking behavior (HP:0030082)1.52611715
74Polydipsia (HP:0001959)1.52611715
75Aplasia/Hypoplasia of the lens (HP:0008063)1.51788896
76Preaxial hand polydactyly (HP:0001177)1.49181568
77Atelectasis (HP:0100750)1.47592849
78Tubulointerstitial fibrosis (HP:0005576)1.47058939
79Aplasia/Hypoplasia of the fibula (HP:0006492)1.45737803
80Decreased central vision (HP:0007663)1.45160459
81Nephropathy (HP:0000112)1.43473806
82Hyperaldosteronism (HP:0000859)1.38788109
83Anencephaly (HP:0002323)1.38325911
84Renal dysplasia (HP:0000110)1.36869435
85Abnormality of the lower motor neuron (HP:0002366)1.36285631
86Hyperkalemia (HP:0002153)1.36056978
8711 pairs of ribs (HP:0000878)1.33661724
88Polycystic kidney dysplasia (HP:0000113)1.32948765
89Abnormality of renin-angiotensin system (HP:0000847)1.32661645
90Constricted visual fields (HP:0001133)1.32210876
91Short thorax (HP:0010306)1.31213754
92Bifid scrotum (HP:0000048)1.31024040
93Gonadotropin excess (HP:0000837)1.30266357
94Abnormality of the renal cortex (HP:0011035)1.29597462
95Retinal dysplasia (HP:0007973)1.27580132
96Short nail (HP:0001799)1.25804944
97Abdominal situs inversus (HP:0003363)1.25061587
98Abnormality of abdominal situs (HP:0011620)1.25061587
99Bifid tongue (HP:0010297)1.24933698
100Abnormality of saccadic eye movements (HP:0000570)1.24108798
101Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.23875451
102Amyotrophic lateral sclerosis (HP:0007354)1.22990662
103Neoplasm of head and neck (HP:0012288)1.22848415
104Esophageal neoplasm (HP:0100751)1.22848415
105Short tibia (HP:0005736)1.22519634
106Impulsivity (HP:0100710)1.21136091
107Male pseudohermaphroditism (HP:0000037)1.20579084
108Ectopic anus (HP:0004397)1.20018158
109Sclerocornea (HP:0000647)1.19187117
110J-shaped sella turcica (HP:0002680)1.16691372
111Abnormal connection of the cardiac segments (HP:0011545)1.16463672
112Abnormal ventriculo-arterial connection (HP:0011563)1.16463672
113Transposition of the great arteries (HP:0001669)1.16463672
114Bell-shaped thorax (HP:0001591)1.15002979
115Hypokalemic alkalosis (HP:0001949)1.14229003
116Abnormality of chloride homeostasis (HP:0011422)1.12987561
117Narrow forehead (HP:0000341)1.07711623
118Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.05940316
119Abnormality of the frontal sinuses (HP:0002687)1.03661128
120Retinitis pigmentosa (HP:0000510)1.01785776
121Prominent nasal bridge (HP:0000426)1.01224287
122Aganglionic megacolon (HP:0002251)0.99514944
123Cone-rod dystrophy (HP:0000548)0.98096846
124Aplasia/Hypoplasia involving the sinuses (HP:0009120)0.97412684
125Anophthalmia (HP:0000528)0.96610962
126Fetal akinesia sequence (HP:0001989)0.95801447
127Absent rod-and cone-mediated responses on ERG (HP:0007688)0.94725182
128Hyponatremia (HP:0002902)0.93460597
129Short femoral neck (HP:0100864)0.92895480
130Abnormality of the distal phalanges of the toes (HP:0010182)0.92455170

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.63848389
2PDK47.63848389
3MAPK155.90077281
4PNCK5.16301118
5PDK25.00707262
6TESK14.16445367
7EPHA23.44992179
8PRKD33.07567606
9ICK2.73867986
10PTK2B2.63940790
11STK392.21783988
12WNK42.18116950
13MAPKAPK32.09436731
14TSSK62.02324399
15STK241.65239777
16NME11.48571732
17MAP3K21.48409101
18WEE11.42469444
19STK381.17910775
20NTRK21.13832616
21SMG11.08064325
22TLK11.06918460
23MAP3K31.06351318
24EPHA31.05803989
25NEK21.00803644
26PAK20.97105892
27EPHB10.97010180
28LMTK20.94359261
29MAP2K70.93178178
30LRRK20.90731843
31VRK10.90334859
32DYRK30.89933467
33BCR0.88365315
34WNK10.81531297
35PIK3CG0.79698891
36PDK10.79682122
37IRAK10.77721905
38ERBB30.74620306
39EEF2K0.69586334
40INSRR0.68360391
41DYRK1B0.67349294
42GRK10.62676776
43PRKCG0.61918088
44MAP3K70.60398371
45TAOK10.60010284
46STK30.59172528
47MUSK0.58408578
48STK160.57915898
49MAPKAPK50.56007864
50PRKCI0.55844223
51MARK20.54046867
52ERBB20.53386176
53CASK0.51329622
54MST1R0.51196176
55TRPM70.50489481
56PINK10.49406884
57STK38L0.48875600
58MAP3K120.48496477
59EPHA40.48434022
60TYRO30.47881366
61CDK30.46126432
62BRSK20.45746843
63TBK10.45463783
64MET0.44261652
65CAMK2G0.43330716
66YES10.43002814
67CCNB10.41330009
68NEK90.40691328
69STK100.38606600
70CHEK20.38364364
71CAMK1G0.37590367
72PRKCD0.37025918
73TESK20.36452002
74MAPK130.36323517
75PASK0.35979152
76MAP2K20.33688047
77MAP2K60.33311162
78GSK3A0.33245187
79GRK60.31955332
80MYLK0.31731245
81RIPK40.31125685
82PDPK10.30729615
83SGK10.30553693
84LATS10.29695913
85MST40.28908589
86MAP3K40.28669363
87RPS6KB20.28510892
88AURKA0.26552188
89CAMKK20.25956856
90PRKG10.25463121
91ATM0.25136827
92GRK50.23414181
93ABL10.22770929
94DYRK1A0.22433707
95ADRBK10.22086959
96RET0.21933357
97PBK0.21786136
98PIM20.21196603
99CAMKK10.20505717
100NEK60.19181859
101PAK10.18747117
102CAMK2A0.18384928
103RPS6KA20.18301536
104PRKCQ0.17983267
105CHEK10.17847756
106DAPK20.16101943
107ROCK10.15528144
108PRKDC0.14518684
109CDC70.14371482
110PRKAA20.13832657
111ROCK20.13691941
112TTK0.13643909
113PRKD10.12974342
114MAP2K40.12731344
115MINK10.12392772
116NLK0.12273519
117PRKD20.12217983
118PRKCZ0.11279436
119PTK60.11198528
120BMPR20.11143335
121PLK30.11125660
122PRKACG0.10856328
123FGFR20.10632317
124MARK10.10361330
125RPS6KA10.10326386
126AKT20.09947925
127PLK10.09860639
128TEC0.09800086
129ITK0.09662158
130CDK80.09660320
131CSNK2A10.09423039
132PRKACA0.09136234
133FGR0.08995439
134ATR0.08853932
135PRKACB0.08775067
136NTRK30.08302213
137SRC0.08214429
138PLK40.08197045
139MAP3K60.08190344
140CSNK2A20.08008015
141CSK0.07830776
142IRAK20.07507854
143MAPK100.07250680
144MAP3K100.07030020
145PRKAA10.05924563
146RPS6KB10.05528348
147PKN10.05520398
148MARK30.05423447
149IGF1R0.04986921
150PRKCA0.04739891
151PAK60.04619668
152CSNK1E0.03572298
153INSR0.02994008
154CDK50.02173852
155MAPKAPK20.02080850
156RPS6KA30.01842436

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.74065490
2Phenylalanine metabolism_Homo sapiens_hsa003604.46355845
3Histidine metabolism_Homo sapiens_hsa003404.34179429
4Tyrosine metabolism_Homo sapiens_hsa003503.64002338
5Pyruvate metabolism_Homo sapiens_hsa006203.28888929
6Huntingtons disease_Homo sapiens_hsa050163.10689780
7Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.04561597
8beta-Alanine metabolism_Homo sapiens_hsa004102.89905118
9Propanoate metabolism_Homo sapiens_hsa006402.68876779
10Fatty acid biosynthesis_Homo sapiens_hsa000612.66443872
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.42747503
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.42343619
13Linoleic acid metabolism_Homo sapiens_hsa005912.38697200
14Glucagon signaling pathway_Homo sapiens_hsa049222.22384749
15Basal transcription factors_Homo sapiens_hsa030222.18768283
16Pentose phosphate pathway_Homo sapiens_hsa000302.18544983
17Amphetamine addiction_Homo sapiens_hsa050312.17540775
18Caffeine metabolism_Homo sapiens_hsa002321.87399513
19Dorso-ventral axis formation_Homo sapiens_hsa043201.84928146
20Carbohydrate digestion and absorption_Homo sapiens_hsa049731.79238904
21PPAR signaling pathway_Homo sapiens_hsa033201.77766113
22Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.76152753
23Ether lipid metabolism_Homo sapiens_hsa005651.70073963
24Glycerolipid metabolism_Homo sapiens_hsa005611.68837541
25Fanconi anemia pathway_Homo sapiens_hsa034601.59957669
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.58671293
27Mineral absorption_Homo sapiens_hsa049781.57000042
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.50586919
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.48307160
30Glycerophospholipid metabolism_Homo sapiens_hsa005641.42813875
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.38568069
32Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.37840264
33Cardiac muscle contraction_Homo sapiens_hsa042601.37829465
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.37652480
35Oocyte meiosis_Homo sapiens_hsa041141.37538685
36Antigen processing and presentation_Homo sapiens_hsa046121.29414954
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.27819544
38Estrogen signaling pathway_Homo sapiens_hsa049151.26930508
39Peroxisome_Homo sapiens_hsa041461.26580374
40Renin secretion_Homo sapiens_hsa049241.25068127
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.24435100
42Fructose and mannose metabolism_Homo sapiens_hsa000511.24132370
43Tight junction_Homo sapiens_hsa045301.17917901
44Olfactory transduction_Homo sapiens_hsa047401.13945219
45ABC transporters_Homo sapiens_hsa020101.12243518
46Selenocompound metabolism_Homo sapiens_hsa004501.11921951
47Notch signaling pathway_Homo sapiens_hsa043301.11436044
48Insulin secretion_Homo sapiens_hsa049111.11233115
49Purine metabolism_Homo sapiens_hsa002301.11181643
50Fatty acid degradation_Homo sapiens_hsa000711.10286436
51Glutathione metabolism_Homo sapiens_hsa004801.04815008
52Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.01708853
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.00476216
54Glycosaminoglycan degradation_Homo sapiens_hsa005310.96515251
55Hedgehog signaling pathway_Homo sapiens_hsa043400.91050252
56Primary bile acid biosynthesis_Homo sapiens_hsa001200.90773146
57Calcium signaling pathway_Homo sapiens_hsa040200.89930994
58Taste transduction_Homo sapiens_hsa047420.89193451
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.89073230
60Renin-angiotensin system_Homo sapiens_hsa046140.87650258
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85132069
62Fat digestion and absorption_Homo sapiens_hsa049750.84114615
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.82553755
64Cocaine addiction_Homo sapiens_hsa050300.81292437
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80995949
66Gastric acid secretion_Homo sapiens_hsa049710.80284110
67Arachidonic acid metabolism_Homo sapiens_hsa005900.80129823
68Long-term potentiation_Homo sapiens_hsa047200.78494033
69Carbon metabolism_Homo sapiens_hsa012000.78314536
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77428658
71Systemic lupus erythematosus_Homo sapiens_hsa053220.77058058
72Circadian rhythm_Homo sapiens_hsa047100.73195922
73Nicotine addiction_Homo sapiens_hsa050330.72971223
74Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72898938
75Chemical carcinogenesis_Homo sapiens_hsa052040.72233527
76Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.71891929
77Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71597782
78Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.71331850
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.68306252
80Thyroid hormone synthesis_Homo sapiens_hsa049180.68020932
81Sphingolipid metabolism_Homo sapiens_hsa006000.66887066
82Phototransduction_Homo sapiens_hsa047440.66456341
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63979757
84Glutamatergic synapse_Homo sapiens_hsa047240.63896201
85Circadian entrainment_Homo sapiens_hsa047130.61005434
86Inositol phosphate metabolism_Homo sapiens_hsa005620.59305774
87Axon guidance_Homo sapiens_hsa043600.58564420
88Choline metabolism in cancer_Homo sapiens_hsa052310.58268337
89Retinol metabolism_Homo sapiens_hsa008300.58024341
90cAMP signaling pathway_Homo sapiens_hsa040240.57412314
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.57198215
92Wnt signaling pathway_Homo sapiens_hsa043100.56467083
93Starch and sucrose metabolism_Homo sapiens_hsa005000.55580400
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53807818
95Nitrogen metabolism_Homo sapiens_hsa009100.51966392
96Synaptic vesicle cycle_Homo sapiens_hsa047210.50743884
97Butanoate metabolism_Homo sapiens_hsa006500.49987869
98Collecting duct acid secretion_Homo sapiens_hsa049660.48828818
99Hippo signaling pathway_Homo sapiens_hsa043900.48566322
100Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.48278304
101Alzheimers disease_Homo sapiens_hsa050100.47471833
102Salivary secretion_Homo sapiens_hsa049700.46331515
103Central carbon metabolism in cancer_Homo sapiens_hsa052300.45649313
104Vitamin digestion and absorption_Homo sapiens_hsa049770.44503023
105Fatty acid metabolism_Homo sapiens_hsa012120.44442420
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44008461
107Dopaminergic synapse_Homo sapiens_hsa047280.43813736
108Maturity onset diabetes of the young_Homo sapiens_hsa049500.43681828
109Leukocyte transendothelial migration_Homo sapiens_hsa046700.43412875
110Oxidative phosphorylation_Homo sapiens_hsa001900.42836000
111Bile secretion_Homo sapiens_hsa049760.41840316
112Drug metabolism - other enzymes_Homo sapiens_hsa009830.41074943
113Pancreatic secretion_Homo sapiens_hsa049720.40994564
114Alcoholism_Homo sapiens_hsa050340.40728850
115Metabolic pathways_Homo sapiens_hsa011000.39997570
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39330303
117Sulfur metabolism_Homo sapiens_hsa009200.38388613
118B cell receptor signaling pathway_Homo sapiens_hsa046620.38190230
119AMPK signaling pathway_Homo sapiens_hsa041520.37860870
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37060155
121Complement and coagulation cascades_Homo sapiens_hsa046100.36581436
122Arginine and proline metabolism_Homo sapiens_hsa003300.35510827
123Parkinsons disease_Homo sapiens_hsa050120.35174372
124Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35101955
125Adipocytokine signaling pathway_Homo sapiens_hsa049200.34595898
126Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.33876250
127mRNA surveillance pathway_Homo sapiens_hsa030150.32589881
128Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31521896
129Basal cell carcinoma_Homo sapiens_hsa052170.30615187
130Hepatitis C_Homo sapiens_hsa051600.28864026
131Biosynthesis of amino acids_Homo sapiens_hsa012300.28707926
132Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.27522118
133Viral carcinogenesis_Homo sapiens_hsa052030.27078605
134Transcriptional misregulation in cancer_Homo sapiens_hsa052020.24778956
135Serotonergic synapse_Homo sapiens_hsa047260.23671246
136Melanogenesis_Homo sapiens_hsa049160.21371023
137Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.21133425
138Tryptophan metabolism_Homo sapiens_hsa003800.20815640
139Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.20229866
140Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19864980
141Amoebiasis_Homo sapiens_hsa051460.16496176
142Steroid biosynthesis_Homo sapiens_hsa001000.16128946
143Cyanoamino acid metabolism_Homo sapiens_hsa004600.15476267
144Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.11316051
145Prion diseases_Homo sapiens_hsa050200.11283325
146Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.10915595
147Hematopoietic cell lineage_Homo sapiens_hsa046400.10303548
148Adherens junction_Homo sapiens_hsa045200.10118704
149Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.10106505

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