MORF4L2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)7.01779774
2Golgi transport vesicle coating (GO:0048200)7.01779774
3protein maturation by protein folding (GO:0022417)4.23817821
4cullin deneddylation (GO:0010388)4.18127483
5maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.17182717
6protein deneddylation (GO:0000338)3.68624296
7retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.67107940
8proteasome assembly (GO:0043248)3.64774154
9protein retention in ER lumen (GO:0006621)3.51535439
10ER overload response (GO:0006983)3.35276924
11COPII vesicle coating (GO:0048208)3.27289877
12vesicle coating (GO:0006901)3.23957855
13DNA double-strand break processing (GO:0000729)3.11290615
14protein localization to kinetochore (GO:0034501)3.00697629
15DNA damage response, detection of DNA damage (GO:0042769)3.00135258
16histone H2A acetylation (GO:0043968)2.87223234
17metaphase plate congression (GO:0051310)2.85226106
18DNA ligation (GO:0006266)2.81601780
19cholesterol biosynthetic process (GO:0006695)2.75186671
20mitotic metaphase plate congression (GO:0007080)2.75088650
21de novo protein folding (GO:0006458)2.73321600
22signal peptide processing (GO:0006465)2.71887196
23establishment of integrated proviral latency (GO:0075713)2.64225684
24establishment of protein localization to mitochondrial membrane (GO:0090151)2.63900246
25chromatin remodeling at centromere (GO:0031055)2.61654858
26CENP-A containing nucleosome assembly (GO:0034080)2.58792223
27activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.57807169
28mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.56709887
29protein neddylation (GO:0045116)2.55921817
30sterol biosynthetic process (GO:0016126)2.55346584
31ventricular cardiac muscle cell development (GO:0055015)2.54028415
32spindle checkpoint (GO:0031577)2.53676891
33positive regulation of nuclease activity (GO:0032075)2.52786416
34de novo posttranslational protein folding (GO:0051084)2.52577959
35protein peptidyl-prolyl isomerization (GO:0000413)2.50971923
36nuclear pore organization (GO:0006999)2.50005124
37peptidyl-arginine omega-N-methylation (GO:0035247)2.49543962
38chaperone-mediated protein folding (GO:0061077)2.49089152
39non-recombinational repair (GO:0000726)2.48560733
40double-strand break repair via nonhomologous end joining (GO:0006303)2.48560733
41peptide hormone processing (GO:0016486)2.46344917
42positive regulation of cellular response to oxidative stress (GO:1900409)2.45718001
43positive regulation of response to oxidative stress (GO:1902884)2.45718001
44mitotic sister chromatid segregation (GO:0000070)2.44100897
45organelle disassembly (GO:1903008)2.43709120
46positive regulation of mitochondrial fission (GO:0090141)2.43196039
47sister chromatid segregation (GO:0000819)2.42614960
48folic acid-containing compound biosynthetic process (GO:0009396)2.42446918
49peptidyl-proline modification (GO:0018208)2.41198142
50chondrocyte development (GO:0002063)2.40570268
51mitotic spindle checkpoint (GO:0071174)2.40386876
52histone arginine methylation (GO:0034969)2.40318502
53negative regulation of microtubule polymerization (GO:0031115)2.37719561
54ER to Golgi vesicle-mediated transport (GO:0006888)2.36785013
55regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.36274986
56negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.34526354
57lipid particle organization (GO:0034389)2.34118801
58regulation of coenzyme metabolic process (GO:0051196)2.33215347
59regulation of cofactor metabolic process (GO:0051193)2.33215347
60negative regulation of DNA recombination (GO:0045910)2.32990285
61apical protein localization (GO:0045176)2.31247983
62histone exchange (GO:0043486)2.30664240
63regulation of nuclease activity (GO:0032069)2.30405573
64positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.29863250
65regulation of centriole replication (GO:0046599)2.28746726
66formation of translation preinitiation complex (GO:0001731)2.28676795
67establishment of viral latency (GO:0019043)2.28672402
68kinetochore organization (GO:0051383)2.28468174
69nuclear pore complex assembly (GO:0051292)2.28381068
70body morphogenesis (GO:0010171)2.28357132
71peptidyl-arginine methylation (GO:0018216)2.28040459
72peptidyl-arginine N-methylation (GO:0035246)2.28040459
73mitotic spindle organization (GO:0007052)2.26840984
74protein localization to chromosome, centromeric region (GO:0071459)2.26054464
75protein K11-linked ubiquitination (GO:0070979)2.25329616
76regulation of mitotic spindle organization (GO:0060236)2.23009556
77anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.22843261
78resolution of meiotic recombination intermediates (GO:0000712)2.21986331
79RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.21921003
80tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.21921003
81pyrimidine nucleobase catabolic process (GO:0006208)2.21883336
82protein N-linked glycosylation via asparagine (GO:0018279)2.20653556
83isoprenoid biosynthetic process (GO:0008299)2.20592182
84L-serine metabolic process (GO:0006563)2.19899302
85polarized epithelial cell differentiation (GO:0030859)2.19575479
86negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.19520994
87negative regulation of ligase activity (GO:0051352)2.19520994
88ATP synthesis coupled proton transport (GO:0015986)2.18875947
89energy coupled proton transport, down electrochemical gradient (GO:0015985)2.18875947
90peptidyl-asparagine modification (GO:0018196)2.17970770
91nucleobase biosynthetic process (GO:0046112)2.17843157
92microtubule depolymerization (GO:0007019)2.17833879
93limb bud formation (GO:0060174)2.16873091
94endocrine pancreas development (GO:0031018)2.16774554
95tRNA aminoacylation for protein translation (GO:0006418)2.16773492
96intraciliary transport (GO:0042073)2.16752000
97attachment of spindle microtubules to kinetochore (GO:0008608)2.16661187
98establishment of chromosome localization (GO:0051303)2.16489075
99female gonad development (GO:0008585)2.16041727
100protein localization to chromosome (GO:0034502)2.15823797
101sequestering of metal ion (GO:0051238)2.15663842
102regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.15525182
103peptidyl-cysteine modification (GO:0018198)2.15356679
104mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.13761335
105spindle assembly checkpoint (GO:0071173)2.13720985
106negative regulation of mitotic sister chromatid segregation (GO:0033048)2.13578294
107negative regulation of mitotic sister chromatid separation (GO:2000816)2.13578294
108negative regulation of sister chromatid segregation (GO:0033046)2.13578294
109negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.13578294
110negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.13578294
111endoplasmic reticulum unfolded protein response (GO:0030968)2.12929687
112dopamine biosynthetic process (GO:0042416)2.12075021
113tricarboxylic acid cycle (GO:0006099)2.11189371
114DNA unwinding involved in DNA replication (GO:0006268)2.11090775
115energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.10916811
116ATP hydrolysis coupled proton transport (GO:0015991)2.10916811
117regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.10834052
118mitotic spindle assembly checkpoint (GO:0007094)2.10601275
119cellular response to topologically incorrect protein (GO:0035967)2.10166923
120regulation of acyl-CoA biosynthetic process (GO:0050812)2.10142786
121regulation of gene silencing by RNA (GO:0060966)2.09375270
122regulation of posttranscriptional gene silencing (GO:0060147)2.09375270
123regulation of gene silencing by miRNA (GO:0060964)2.09375270
124regulation of cellular amino acid metabolic process (GO:0006521)2.09178589
125amino acid activation (GO:0043038)2.08719534
126tRNA aminoacylation (GO:0043039)2.08719534
127toxin metabolic process (GO:0009404)2.08621104
128positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.08335738
129regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.08201694
130negative regulation of chromosome segregation (GO:0051985)2.08097769
131presynaptic membrane assembly (GO:0097105)2.07943521
132cellular response to unfolded protein (GO:0034620)2.07618903
133collagen fibril organization (GO:0030199)2.07474046
134mitotic sister chromatid cohesion (GO:0007064)2.07095533
135regulation of chromosome segregation (GO:0051983)2.06501351
136ribosome assembly (GO:0042255)2.06216319
137regulation of spindle organization (GO:0090224)2.05099701
138aldehyde catabolic process (GO:0046185)2.04376438
139protein localization to cilium (GO:0061512)2.02695202
1407-methylguanosine mRNA capping (GO:0006370)2.02317583
141protein N-linked glycosylation (GO:0006487)2.02247958
142DNA catabolic process, exonucleolytic (GO:0000738)2.02218276
143ER-nucleus signaling pathway (GO:0006984)2.02078673
144chaperone-mediated protein transport (GO:0072321)2.01596663
145regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.01574135
146regulation of mitotic spindle checkpoint (GO:1903504)2.01574135
147intra-Golgi vesicle-mediated transport (GO:0006891)2.01377861
1487-methylguanosine RNA capping (GO:0009452)2.00743150
149RNA capping (GO:0036260)2.00743150
150ribonucleoprotein complex disassembly (GO:0032988)2.00699659
151establishment of monopolar cell polarity (GO:0061162)2.00580048
152establishment or maintenance of monopolar cell polarity (GO:0061339)2.00580048
153regulation of ubiquitin-protein transferase activity (GO:0051438)1.99675615
154regulation of type B pancreatic cell apoptotic process (GO:2000674)1.99338632
155positive regulation of receptor biosynthetic process (GO:0010870)1.99254157
156purine nucleobase biosynthetic process (GO:0009113)1.98955528
157DNA replication-independent nucleosome assembly (GO:0006336)1.98779449
158DNA replication-independent nucleosome organization (GO:0034724)1.98779449
159detection of calcium ion (GO:0005513)1.98704649
160kinetochore assembly (GO:0051382)1.98407190
161transferrin transport (GO:0033572)1.97583004
162type B pancreatic cell development (GO:0003323)1.96872157
163protein folding (GO:0006457)1.96112944
164L-methionine biosynthetic process from methylthioadenosine (GO:0019509)1.95714986
165response to hepatocyte growth factor (GO:0035728)1.95182630
166cellular response to hepatocyte growth factor stimulus (GO:0035729)1.95182630
167positive regulation of ligase activity (GO:0051351)1.94282709
168protein K6-linked ubiquitination (GO:0085020)1.94104537
169establishment of apical/basal cell polarity (GO:0035089)1.93934913
170lactate metabolic process (GO:0006089)1.93477068
171DNA replication-dependent nucleosome organization (GO:0034723)1.92809188
172DNA replication-dependent nucleosome assembly (GO:0006335)1.92809188

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.83527786
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.57422967
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.08982478
4* GABP_17652178_ChIP-ChIP_JURKAT_Human3.04341973
5MYC_18555785_ChIP-Seq_MESCs_Mouse2.80762205
6HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.53478944
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.52909079
8CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.45727987
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.23028870
10KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.19434903
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.19166595
12PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.14034326
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.10610842
14* ELK1_19687146_ChIP-ChIP_HELA_Human2.10350275
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.10247876
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.09104189
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.03158914
18MYC_19030024_ChIP-ChIP_MESCs_Mouse1.98968222
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.95060816
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.92666161
21ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89356898
22* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.87780966
23THAP11_20581084_ChIP-Seq_MESCs_Mouse1.86483090
24PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.86155941
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.85064054
26PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79372616
27TAF15_26573619_Chip-Seq_HEK293_Human1.78998110
28* WT1_19549856_ChIP-ChIP_CCG9911_Human1.78028301
29* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.76782593
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.76703303
31E2F7_22180533_ChIP-Seq_HELA_Human1.76478271
32FUS_26573619_Chip-Seq_HEK293_Human1.73301389
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.72861055
34ZFX_18555785_ChIP-Seq_MESCs_Mouse1.72769369
35* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72015994
36CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.66914562
37ZNF274_21170338_ChIP-Seq_K562_Hela1.63229846
38* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62887409
39HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.61037587
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.60082035
41XRN2_22483619_ChIP-Seq_HELA_Human1.55910857
42* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.54783649
43E2F4_17652178_ChIP-ChIP_JURKAT_Human1.54205564
44PADI4_21655091_ChIP-ChIP_MCF-7_Human1.52876269
45* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52363780
46GABP_19822575_ChIP-Seq_HepG2_Human1.50125682
47DCP1A_22483619_ChIP-Seq_HELA_Human1.47346658
48GBX2_23144817_ChIP-Seq_PC3_Human1.46775808
49P300_19829295_ChIP-Seq_ESCs_Human1.44770613
50* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.44252190
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.41692818
52TTF2_22483619_ChIP-Seq_HELA_Human1.41572269
53CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.41498479
54REST_19997604_ChIP-ChIP_NEURONS_Mouse1.41203235
55SOX17_20123909_ChIP-Seq_XEN_Mouse1.41144028
56POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37882120
57SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.37697667
58* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.36928223
59POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.35812814
60ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.35730260
61VDR_23849224_ChIP-Seq_CD4+_Human1.35187702
62TRIM28_21343339_ChIP-Seq_HEK293_Human1.34953410
63* NANOG_16153702_ChIP-ChIP_HESCs_Human1.34498760
64NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.33823453
65CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.33434314
66* DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.33266643
67AR_21909140_ChIP-Seq_LNCAP_Human1.32836929
68MYC_18940864_ChIP-ChIP_HL60_Human1.31708026
69SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.31427479
70VDR_22108803_ChIP-Seq_LS180_Human1.31046829
71* SOX2_16153702_ChIP-ChIP_HESCs_Human1.30910999
72CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27912859
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26040848
74EWS_26573619_Chip-Seq_HEK293_Human1.25855823
75POU3F2_20337985_ChIP-ChIP_501MEL_Human1.23350272
76ELK1_22589737_ChIP-Seq_MCF10A_Human1.19343081
77IGF1R_20145208_ChIP-Seq_DFB_Human1.17537830
78ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.16924633
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14713846
80FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.14234172
81* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.14086689
82TFEB_21752829_ChIP-Seq_HELA_Human1.14036281
83TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13745009
84FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12965564
85MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.12286084
86RNF2_27304074_Chip-Seq_NSC_Mouse1.10873455
87AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.10824280
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10744762
89POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.10108062
90CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.09893676
91TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.08652008
92HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.06870351
93MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06423309
94* CLOCK_20551151_ChIP-Seq_293T_Human1.04981958
95CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04528361
96SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.04347055
97MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03881672
98ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.03430974
99FLI1_27457419_Chip-Seq_LIVER_Mouse1.03072291
100KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02536435
101PIAS1_25552417_ChIP-Seq_VCAP_Human1.01952760
102SMAD4_21799915_ChIP-Seq_A2780_Human1.01344196
103KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.01279276
104KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.01279276
105KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.01279276
106E2F1_21310950_ChIP-Seq_MCF-7_Human1.00096570
107TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99776407
108TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99632367
109SMAD3_21741376_ChIP-Seq_EPCs_Human0.98970356
110CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97798292
111ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.97539834
112FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.97175929
113SOX9_26525672_Chip-Seq_HEART_Mouse0.96698221
114SRF_21415370_ChIP-Seq_HL-1_Mouse0.96042093
115CBX2_27304074_Chip-Seq_ESCs_Mouse0.94669093
116SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94140736
117JUN_21703547_ChIP-Seq_K562_Human0.93984461
118NANOG_21062744_ChIP-ChIP_HESCs_Human0.93972311
119KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93967535
120RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.92983848
121TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.91574351
122SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90768418
123POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89770497
124EZH2_22144423_ChIP-Seq_EOC_Human0.89682117
125YY1_21170310_ChIP-Seq_MESCs_Mouse0.87044619
126FOXP3_21729870_ChIP-Seq_TREG_Human0.86677234
127UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.85988009
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85677844
129EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.84495203
130EZH2_27304074_Chip-Seq_ESCs_Mouse0.84091150

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting3.92021021
2MP0003123_paternal_imprinting3.58298380
3MP0003283_abnormal_digestive_organ3.01935819
4MP0003121_genomic_imprinting2.81338376
5MP0008438_abnormal_cutaneous_collagen2.53829023
6MP0000013_abnormal_adipose_tissue2.36895104
7MP0010386_abnormal_urinary_bladder2.16640611
8MP0002102_abnormal_ear_morphology2.13582159
9MP0009780_abnormal_chondrocyte_physiolo2.12297754
10MP0008058_abnormal_DNA_repair2.07177803
11MP0004272_abnormal_basement_membrane2.01244519
12MP0000537_abnormal_urethra_morphology1.92857878
13MP0005503_abnormal_tendon_morphology1.86917495
14MP0003119_abnormal_digestive_system1.78245161
15MP0002909_abnormal_adrenal_gland1.73721908
16MP0010094_abnormal_chromosome_stability1.69645950
17MP0002877_abnormal_melanocyte_morpholog1.67655081
18MP0003787_abnormal_imprinting1.67495652
19MP0008789_abnormal_olfactory_epithelium1.66652155
20MP0004957_abnormal_blastocyst_morpholog1.63089780
21MP0009697_abnormal_copulation1.62075679
22MP0006054_spinal_hemorrhage1.60190645
23MP0003890_abnormal_embryonic-extraembry1.59638798
24MP0004133_heterotaxia1.55811923
25MP0005394_taste/olfaction_phenotype1.54178148
26MP0005499_abnormal_olfactory_system1.54178148
27MP0003942_abnormal_urinary_system1.51018717
28MP0008932_abnormal_embryonic_tissue1.49278180
29MP0010030_abnormal_orbit_morphology1.49144227
30MP0003941_abnormal_skin_development1.48651746
31MP0004264_abnormal_extraembryonic_tissu1.47997769
32MP0006072_abnormal_retinal_apoptosis1.47116399
33MP0004270_analgesia1.38732723
34MP0003718_maternal_effect1.38435279
35MP0001299_abnormal_eye_distance/1.38064791
36MP0001984_abnormal_olfaction1.36738096
37MP0005275_abnormal_skin_tensile1.36244451
38MP0005623_abnormal_meninges_morphology1.35417806
39MP0001293_anophthalmia1.35264131
40MP0003937_abnormal_limbs/digits/tail_de1.34511366
41MP0002896_abnormal_bone_mineralization1.33425883
42MP0002938_white_spotting1.33259171
43MP0000631_abnormal_neuroendocrine_gland1.32163460
44MP0005187_abnormal_penis_morphology1.28823813
45MP0002751_abnormal_autonomic_nervous1.26248379
46MP0000462_abnormal_digestive_system1.25940507
47MP0000372_irregular_coat_pigmentation1.24788618
48MP0006276_abnormal_autonomic_nervous1.22728578
49MP0003385_abnormal_body_wall1.22403150
50MP0002837_dystrophic_cardiac_calcinosis1.22119741
51MP0003111_abnormal_nucleus_morphology1.21442110
52MP0003880_abnormal_central_pattern1.21231431
53MP0002084_abnormal_developmental_patter1.18331662
54MP0002697_abnormal_eye_size1.17492624
55MP0004134_abnormal_chest_morphology1.16912092
56MP0001944_abnormal_pancreas_morphology1.14848805
57MP0003755_abnormal_palate_morphology1.14239846
58MP0000678_abnormal_parathyroid_gland1.13990579
59MP0009046_muscle_twitch1.13212820
60MP0009250_abnormal_appendicular_skeleto1.12979695
61MP0001529_abnormal_vocalization1.12831574
62MP0002653_abnormal_ependyma_morphology1.11127393
63MP0000647_abnormal_sebaceous_gland1.10164237
64MP0001177_atelectasis1.07446417
65MP0004197_abnormal_fetal_growth/weight/1.06920713
66MP0000778_abnormal_nervous_system1.05968858
67MP0002184_abnormal_innervation1.05911437
68MP0002282_abnormal_trachea_morphology1.03708735
69MP0002734_abnormal_mechanical_nocicepti1.02792195
70MP0000428_abnormal_craniofacial_morphol1.01990222
71MP0000049_abnormal_middle_ear1.01883304
72MP0005253_abnormal_eye_physiology1.01236782
73MP0002736_abnormal_nociception_after1.00720642
74MP0000003_abnormal_adipose_tissue1.00602711
75MP0003567_abnormal_fetal_cardiomyocyte1.00496381
76MP0001286_abnormal_eye_development1.00412624
77MP0004233_abnormal_muscle_weight0.99203047
78MP0003786_premature_aging0.98893362
79MP0003693_abnormal_embryo_hatching0.98610160
80MP0000534_abnormal_ureter_morphology0.98500955
81MP0001730_embryonic_growth_arrest0.98464276
82MP0002234_abnormal_pharynx_morphology0.97842799
83MP0005220_abnormal_exocrine_pancreas0.97479362
84MP0005379_endocrine/exocrine_gland_phen0.97248146
85MP0002693_abnormal_pancreas_physiology0.94547232
86MP0001697_abnormal_embryo_size0.92541780
87MP0002085_abnormal_embryonic_tissue0.92454448
88MP0006292_abnormal_olfactory_placode0.91787632
89MP0009672_abnormal_birth_weight0.91427177
90MP0005645_abnormal_hypothalamus_physiol0.91134511
91MP0005508_abnormal_skeleton_morphology0.90666139
92MP0002111_abnormal_tail_morphology0.89749558
93MP0002116_abnormal_craniofacial_bone0.89349932
94MP0008995_early_reproductive_senescence0.88450700
95MP0002177_abnormal_outer_ear0.88382249
96MP0003635_abnormal_synaptic_transmissio0.88248610
97MP0000516_abnormal_urinary_system0.88237610
98MP0005367_renal/urinary_system_phenotyp0.88237610
99MP0008057_abnormal_DNA_replication0.87841904
100MP0002160_abnormal_reproductive_system0.87534193
101MP0000163_abnormal_cartilage_morphology0.87345717
102MP0002090_abnormal_vision0.86776071
103MP0003861_abnormal_nervous_system0.85759932
104MP0000566_synostosis0.85515072
105MP0004215_abnormal_myocardial_fiber0.84353431
106MP0004043_abnormal_pH_regulation0.84146436
107MP0010352_gastrointestinal_tract_polyps0.83915609
108MP0005646_abnormal_pituitary_gland0.83633517
109MP0005391_vision/eye_phenotype0.82794997
110MP0002210_abnormal_sex_determination0.82602578
111MP0001188_hyperpigmentation0.82463105
112MP0003115_abnormal_respiratory_system0.82250422
113MP0009053_abnormal_anal_canal0.81900062
114MP0002063_abnormal_learning/memory/cond0.81842599
115MP0004147_increased_porphyrin_level0.81698635
116MP0003221_abnormal_cardiomyocyte_apopto0.81600639
117MP0006035_abnormal_mitochondrial_morpho0.80779693
118MP0002233_abnormal_nose_morphology0.80162300
119MP0005380_embryogenesis_phenotype0.79920765
120MP0001672_abnormal_embryogenesis/_devel0.79920765
121MP0000955_abnormal_spinal_cord0.79560754
122MP0005551_abnormal_eye_electrophysiolog0.78219291
123MP0001929_abnormal_gametogenesis0.78016252
124MP0004859_abnormal_synaptic_plasticity0.77969933
125MP0001486_abnormal_startle_reflex0.77849216
126MP0003935_abnormal_craniofacial_develop0.76904004
127MP0009703_decreased_birth_body0.76638673
128MP0005171_absent_coat_pigmentation0.76559027
129MP0005248_abnormal_Harderian_gland0.76482307
130MP0008007_abnormal_cellular_replicative0.75716380
131MP0000358_abnormal_cell_content/0.75529489
132MP0002114_abnormal_axial_skeleton0.75024385
133MP0003183_abnormal_peptide_metabolism0.74174690
134MP0003705_abnormal_hypodermis_morpholog0.73355187
135MP0002557_abnormal_social/conspecific_i0.73217491
136MP0003186_abnormal_redox_activity0.72672820
137MP0004811_abnormal_neuron_physiology0.72025324
138MP0008877_abnormal_DNA_methylation0.71831038
139MP0003077_abnormal_cell_cycle0.71725030
140MP0002152_abnormal_brain_morphology0.71051637
141MP0001905_abnormal_dopamine_level0.70348636
142MP0003315_abnormal_perineum_morphology0.70238372

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of dentin (HP:0010299)3.02301833
2Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.88292609
3Hepatoblastoma (HP:0002884)2.69818810
4Cortical dysplasia (HP:0002539)2.62115647
5Epiphyseal dysplasia (HP:0002656)2.48546588
6Premature rupture of membranes (HP:0001788)2.44675795
7Hyperinsulinemic hypoglycemia (HP:0000825)2.43409440
8Irregular epiphyses (HP:0010582)2.43250787
9Shoulder girdle muscle weakness (HP:0003547)2.34976926
10Abnormal lung lobation (HP:0002101)2.31877442
11Volvulus (HP:0002580)2.30207615
12Hypoglycemic seizures (HP:0002173)2.29140211
13Abnormality of the labia minora (HP:0012880)2.21972721
14Protrusio acetabuli (HP:0003179)2.21340235
15Missing ribs (HP:0000921)2.15156044
16Delayed epiphyseal ossification (HP:0002663)2.09799151
17Abnormal pancreas size (HP:0012094)2.08721045
18Symptomatic seizures (HP:0011145)2.07487838
19Bifid tongue (HP:0010297)2.04437550
20Pheochromocytoma (HP:0002666)2.02204713
21Delayed gross motor development (HP:0002194)2.00476052
22Colon cancer (HP:0003003)1.98524544
23Pancreatic fibrosis (HP:0100732)1.96527922
24Hypoplastic pelvis (HP:0008839)1.95033099
25Neuroendocrine neoplasm (HP:0100634)1.94150033
26Spinal cord compression (HP:0002176)1.93973367
27Ependymoma (HP:0002888)1.92936543
28Increased serum pyruvate (HP:0003542)1.91144087
29Abnormality of glycolysis (HP:0004366)1.91144087
30Pancreatic islet-cell hyperplasia (HP:0004510)1.90907525
31Orthostatic hypotension (HP:0001278)1.90362173
32Mild short stature (HP:0003502)1.89823688
33Abnormal umbilical cord blood vessels (HP:0011403)1.89758088
34Single umbilical artery (HP:0001195)1.89758088
35Abnormality of the fetal cardiovascular system (HP:0010948)1.89758088
36Postnatal microcephaly (HP:0005484)1.88758948
37Neoplasm of the adrenal gland (HP:0100631)1.88312995
38Abnormality of the pancreatic islet cells (HP:0006476)1.87971924
39Abnormality of endocrine pancreas physiology (HP:0012093)1.87971924
40Soft skin (HP:0000977)1.87750724
41Acute encephalopathy (HP:0006846)1.87396913
42Atonic seizures (HP:0010819)1.85659892
43Acute necrotizing encephalopathy (HP:0006965)1.84453082
44Short tibia (HP:0005736)1.84266694
45Abnormality of calcium-phosphate metabolism (HP:0100530)1.83630259
46Increased nuchal translucency (HP:0010880)1.82162191
47Meckel diverticulum (HP:0002245)1.81688069
48Osteomalacia (HP:0002749)1.81513242
49High anterior hairline (HP:0009890)1.81431843
50True hermaphroditism (HP:0010459)1.81254121
51Resting tremor (HP:0002322)1.80955574
52Occipital encephalocele (HP:0002085)1.80529764
53Limb dystonia (HP:0002451)1.78911958
54Flat capital femoral epiphysis (HP:0003370)1.77975791
55Hypoplastic female external genitalia (HP:0012815)1.77709047
56Intestinal atresia (HP:0011100)1.75628884
57Drooling (HP:0002307)1.74106830
58Aplasia/Hypoplasia of the uvula (HP:0010293)1.73938269
59Abnormality of the ileum (HP:0001549)1.73897744
60Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.73687155
61Poor suck (HP:0002033)1.73352454
62Small epiphyses (HP:0010585)1.73224809
63Papillary thyroid carcinoma (HP:0002895)1.72998225
64Epileptiform EEG discharges (HP:0011182)1.72918188
65Upper limb muscle weakness (HP:0003484)1.72888436
66Cervical subluxation (HP:0003308)1.72327283
67EEG with generalized epileptiform discharges (HP:0011198)1.72054925
68Wormian bones (HP:0002645)1.71748107
69Abnormality of the anterior horn cell (HP:0006802)1.71444967
70Degeneration of anterior horn cells (HP:0002398)1.71444967
71Pancreatic cysts (HP:0001737)1.71276464
72Glossoptosis (HP:0000162)1.71142793
73Gait imbalance (HP:0002141)1.70210570
74Metaphyseal cupping (HP:0003021)1.69312938
75Glioma (HP:0009733)1.69094012
76Bell-shaped thorax (HP:0001591)1.68843620
77Preaxial hand polydactyly (HP:0001177)1.68505369
78Hypoplasia of the pons (HP:0012110)1.68332531
79Hypsarrhythmia (HP:0002521)1.68140548
80Vertebral hypoplasia (HP:0008417)1.66272662
81Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.66272662
82Postaxial hand polydactyly (HP:0001162)1.66261568
83Broad foot (HP:0001769)1.65927706
84Decreased testicular size (HP:0008734)1.65516643
85Congenital primary aphakia (HP:0007707)1.65168670
86Molar tooth sign on MRI (HP:0002419)1.64983303
87Abnormality of midbrain morphology (HP:0002418)1.64983303
88Back pain (HP:0003418)1.64613683
89Lissencephaly (HP:0001339)1.64028300
90Agitation (HP:0000713)1.63607014
91Abnormal mitochondria in muscle tissue (HP:0008316)1.62724915
92Abnormality of the calcaneus (HP:0008364)1.62434605
93Aplasia/Hypoplasia of the tibia (HP:0005772)1.62300150
94Abnormality of the pons (HP:0007361)1.62070059
95Abnormality of the astrocytes (HP:0100707)1.61612281
96Astrocytoma (HP:0009592)1.61612281
97Supernumerary spleens (HP:0009799)1.61499342
98Duodenal stenosis (HP:0100867)1.61413620
99Small intestinal stenosis (HP:0012848)1.61413620
100Congenital glaucoma (HP:0001087)1.61411219
101Tubulointerstitial nephritis (HP:0001970)1.60746780
102Abnormal gallbladder physiology (HP:0012438)1.60114056
103Cholecystitis (HP:0001082)1.60114056
104Buphthalmos (HP:0000557)1.59866401
105Abnormality of methionine metabolism (HP:0010901)1.59227679
106Testicular neoplasm (HP:0010788)1.59223913
107Increased CSF lactate (HP:0002490)1.58886379
108Abnormality of chromosome stability (HP:0003220)1.58834412
109Irregular vertebral endplates (HP:0003301)1.58649567
110Aplasia/Hypoplasia of the tongue (HP:0010295)1.58436140
111Retinal dysplasia (HP:0007973)1.58384686
112Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.58352708
113Abnormal protein N-linked glycosylation (HP:0012347)1.58352708
114Abnormal protein glycosylation (HP:0012346)1.58352708
115Abnormal glycosylation (HP:0012345)1.58352708
116Atrophy/Degeneration involving motor neurons (HP:0007373)1.58197355
117Abnormality of the labia (HP:0000058)1.58097100
118Pelvic girdle muscle weakness (HP:0003749)1.57717175
119Labial hypoplasia (HP:0000066)1.57555316
120Methylmalonic acidemia (HP:0002912)1.56770699
121Spastic diplegia (HP:0001264)1.56564555
122Postaxial foot polydactyly (HP:0001830)1.56465555
123Poor coordination (HP:0002370)1.55896444
124Relative macrocephaly (HP:0004482)1.55614886
125Progressive macrocephaly (HP:0004481)1.55059500
126Vaginal atresia (HP:0000148)1.54845534
127Renal hypoplasia (HP:0000089)1.53810105
128Genital tract atresia (HP:0001827)1.53794785
12911 pairs of ribs (HP:0000878)1.53789140
130Stenosis of the external auditory canal (HP:0000402)1.53504609
131Disproportionate short-trunk short stature (HP:0003521)1.53478561
132Hypothermia (HP:0002045)1.52701580
133Myelomeningocele (HP:0002475)1.52327183
134Patent foramen ovale (HP:0001655)1.52116709
135Dysautonomia (HP:0002459)1.51917552
136Optic nerve hypoplasia (HP:0000609)1.51908941
137Dental crowding (HP:0000678)1.51707041
138Muscular hypotonia of the trunk (HP:0008936)1.51505060
139Abnormality of the duodenum (HP:0002246)1.50514953
140Thoracolumbar scoliosis (HP:0002944)1.50490334
141Osteoarthritis (HP:0002758)1.50391363
142Abnormal autonomic nervous system physiology (HP:0012332)1.50366049
143Cerebral edema (HP:0002181)1.49389201
144Broad long bones (HP:0005622)1.49182775
145Medial flaring of the eyebrow (HP:0010747)1.48647834
146Micropenis (HP:0000054)1.48536577
147Facial cleft (HP:0002006)1.48381682
148Hypoventilation (HP:0002791)1.48279930
149Dandy-Walker malformation (HP:0001305)1.48229944
150Intestinal polyposis (HP:0200008)1.48155006
151X-linked dominant inheritance (HP:0001423)1.47671809
152Oligodactyly (hands) (HP:0001180)1.47368647
153Adrenal hypoplasia (HP:0000835)1.47188436
154Abnormality of the hip-girdle musculature (HP:0001445)1.46583562
155Abnormality of the musculature of the pelvis (HP:0001469)1.46583562
156Type II lissencephaly (HP:0007260)1.45989031
157Nephronophthisis (HP:0000090)1.45916590
158Nephrogenic diabetes insipidus (HP:0009806)1.45884744
159Curly hair (HP:0002212)1.45585424
160Broad phalanx (HP:0006009)1.45356621
161Bladder diverticulum (HP:0000015)1.44932975
162Type I transferrin isoform profile (HP:0003642)1.44466957
163Hyperthyroidism (HP:0000836)1.44376776
164Fibular hypoplasia (HP:0003038)1.44232967
165Overlapping toe (HP:0001845)1.43581403
166Split foot (HP:0001839)1.42320368
167Chorioretinal coloboma (HP:0000567)1.40386836
168Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.39943384
169Scrotal hypoplasia (HP:0000046)1.39074563
170Hyperglycinemia (HP:0002154)1.38908608
171Microglossia (HP:0000171)1.38157064

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PASK3.46004846
2TRIM283.33710546
3SCYL22.61350638
4LIMK12.38958218
5TSSK62.36898810
6BCR2.30178887
7PLK22.18665573
8NTRK32.12455100
9MAP4K22.11988055
10BUB11.99341200
11EPHA41.95869231
12PBK1.94285928
13PLK31.93793237
14EIF2AK31.93574707
15WNK31.86910772
16PNCK1.77282318
17DDR21.73837800
18CASK1.73128360
19UHMK11.72517640
20ERBB31.69045050
21BRSK21.62892741
22TESK11.61854582
23FER1.52743387
24LATS21.50327996
25FRK1.49664827
26LATS11.44751606
27PDK21.39334580
28NTRK11.38379727
29SRPK11.37163507
30MAP3K41.36524608
31CSNK1G31.35863361
32CDC71.32544324
33KSR11.31832149
34MAP3K121.28612814
35WEE11.28596605
36NEK11.27627066
37MKNK11.27546089
38MET1.26509518
39PAK31.24648460
40MINK11.24370842
41EPHA21.22430044
42MAP3K21.19311910
43ACVR1B1.18571287
44PDGFRA1.17344916
45STK38L1.11457751
46ARAF1.10805620
47CSNK1G21.09465873
48BRAF1.09041809
49VRK11.06909599
50SIK31.05512598
51CSNK1A1L1.05485107
52NME11.05189502
53CDK141.03906289
54AKT31.01745222
55MAPK151.01239336
56PRKCI1.01190915
57MARK11.00131936
58STK160.98831825
59DYRK20.98476354
60AURKA0.96208790
61CSNK1G10.94956661
62TNIK0.94680993
63PRKD30.93954059
64TGFBR10.92385001
65NUAK10.91534348
66WNK40.91396607
67BRSK10.87339764
68BMPR1B0.86637236
69CDK180.85779586
70ZAK0.85590899
71MST40.85478577
72ERBB40.83065329
73NEK20.82325502
74PLK10.82113653
75STK390.81499187
76INSRR0.79943390
77CDK150.78977794
78FGFR10.78936955
79PTK20.77112074
80FLT30.72588378
81EPHB20.71071262
82MAP2K70.70520508
83CCNB10.70416849
84MAPK130.70066435
85CDK11A0.68894687
86DYRK30.68343665
87ADRBK10.67075504
88OXSR10.65709924
89CDK80.65540967
90PINK10.64846244
91RPS6KB20.63967271
92EIF2AK20.62590022
93ICK0.62337145
94DAPK10.61909668
95MAP2K10.61253208
96MAP3K90.59747694
97TTK0.59489530
98EIF2AK10.59221043
99PAK40.58727546
100MAPKAPK50.58391558
101CDK190.58053968
102VRK20.57745672
103ATR0.56777697
104PLK40.56037260
105KSR20.55642437
106CAMK2B0.55464594
107CAMKK20.54557261
108GRK50.53416941
109ATM0.53267859
110CSNK1E0.52562032
111FGFR20.52527791
112PRKCG0.50543966
113CHEK20.49582681
114STK30.48978134
115DYRK1A0.48822226
116PRKCE0.47394019
117CAMK2A0.44809207
118MKNK20.44780787
119PAK60.43071970
120PAK10.42424354
121AURKB0.42349033
122BCKDK0.42229801
123CHEK10.42210532
124RPS6KA40.40249516
125CAMK2D0.39918851
126CDK70.39885420
127CDK10.34662947
128CSNK2A10.33621257
129GRK10.30919162

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030604.39729295
2Maturity onset diabetes of the young_Homo sapiens_hsa049502.90969545
3Vibrio cholerae infection_Homo sapiens_hsa051102.75246372
4Proteasome_Homo sapiens_hsa030502.64037795
5Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.46127713
6Steroid biosynthesis_Homo sapiens_hsa001002.45811702
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.03913624
8Propanoate metabolism_Homo sapiens_hsa006401.98138574
9Synaptic vesicle cycle_Homo sapiens_hsa047211.91458546
10Oxidative phosphorylation_Homo sapiens_hsa001901.84130631
11RNA transport_Homo sapiens_hsa030131.76590947
12Collecting duct acid secretion_Homo sapiens_hsa049661.70695202
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.70212945
14Alcoholism_Homo sapiens_hsa050341.64050696
15Spliceosome_Homo sapiens_hsa030401.59109354
16RNA polymerase_Homo sapiens_hsa030201.56889355
17Fatty acid elongation_Homo sapiens_hsa000621.56820585
18Pyruvate metabolism_Homo sapiens_hsa006201.55551509
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49199885
20N-Glycan biosynthesis_Homo sapiens_hsa005101.48947409
21Parkinsons disease_Homo sapiens_hsa050121.48023879
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.45945580
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.43769061
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.43613670
25Amphetamine addiction_Homo sapiens_hsa050311.42546832
26Insulin secretion_Homo sapiens_hsa049111.42505588
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.40763600
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.40626470
29Fanconi anemia pathway_Homo sapiens_hsa034601.38831430
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.38296002
31Cocaine addiction_Homo sapiens_hsa050301.32005472
32Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.30132882
33Cell cycle_Homo sapiens_hsa041101.29937950
34Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.27546616
35Huntingtons disease_Homo sapiens_hsa050161.25641041
36Nicotine addiction_Homo sapiens_hsa050331.25470905
37Dopaminergic synapse_Homo sapiens_hsa047281.25112759
38Mismatch repair_Homo sapiens_hsa034301.24749138
39Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.24693207
40Oocyte meiosis_Homo sapiens_hsa041141.23285687
41Nucleotide excision repair_Homo sapiens_hsa034201.23093630
42Homologous recombination_Homo sapiens_hsa034401.23076063
43Biosynthesis of amino acids_Homo sapiens_hsa012301.22720349
44Vitamin B6 metabolism_Homo sapiens_hsa007501.21995338
45Butanoate metabolism_Homo sapiens_hsa006501.18677437
46Carbon metabolism_Homo sapiens_hsa012001.18509868
47Hippo signaling pathway_Homo sapiens_hsa043901.16376242
48Long-term potentiation_Homo sapiens_hsa047201.15481423
49Sulfur metabolism_Homo sapiens_hsa009201.15178285
50Selenocompound metabolism_Homo sapiens_hsa004501.14319092
51Alzheimers disease_Homo sapiens_hsa050101.13771847
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.12929231
53Hedgehog signaling pathway_Homo sapiens_hsa043401.10149170
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.09880281
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.06985701
56mRNA surveillance pathway_Homo sapiens_hsa030151.05207024
57Serotonergic synapse_Homo sapiens_hsa047261.01661924
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.01040403
59RNA degradation_Homo sapiens_hsa030181.00690808
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98148091
61Phototransduction_Homo sapiens_hsa047440.97958385
62Folate biosynthesis_Homo sapiens_hsa007900.95893994
63ECM-receptor interaction_Homo sapiens_hsa045120.93613889
64GABAergic synapse_Homo sapiens_hsa047270.90934403
65Type I diabetes mellitus_Homo sapiens_hsa049400.90561583
66Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90136240
67DNA replication_Homo sapiens_hsa030300.89558500
68Basal transcription factors_Homo sapiens_hsa030220.89458828
69Phagosome_Homo sapiens_hsa041450.88273847
70Circadian entrainment_Homo sapiens_hsa047130.87862769
71Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.86871584
72Gap junction_Homo sapiens_hsa045400.84818718
73Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.84500340
74Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83755497
75Long-term depression_Homo sapiens_hsa047300.82292538
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81217181
77Fatty acid metabolism_Homo sapiens_hsa012120.80962965
78TGF-beta signaling pathway_Homo sapiens_hsa043500.80824856
79Basal cell carcinoma_Homo sapiens_hsa052170.80521262
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80473864
81Arginine and proline metabolism_Homo sapiens_hsa003300.79780971
82Estrogen signaling pathway_Homo sapiens_hsa049150.79078177
83Tight junction_Homo sapiens_hsa045300.77188669
84Systemic lupus erythematosus_Homo sapiens_hsa053220.74740173
85Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.74706767
86Thyroid hormone synthesis_Homo sapiens_hsa049180.73987489
87Taste transduction_Homo sapiens_hsa047420.73671182
88beta-Alanine metabolism_Homo sapiens_hsa004100.73383765
89Axon guidance_Homo sapiens_hsa043600.71464183
90Pyrimidine metabolism_Homo sapiens_hsa002400.71451910
91Wnt signaling pathway_Homo sapiens_hsa043100.70432745
92Glutathione metabolism_Homo sapiens_hsa004800.66695671
93Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.65030908
94Metabolic pathways_Homo sapiens_hsa011000.64773024
95Focal adhesion_Homo sapiens_hsa045100.64049029
96Peroxisome_Homo sapiens_hsa041460.63995473
97Colorectal cancer_Homo sapiens_hsa052100.63322446
98Cholinergic synapse_Homo sapiens_hsa047250.61729957
99Type II diabetes mellitus_Homo sapiens_hsa049300.60276979
100Protein digestion and absorption_Homo sapiens_hsa049740.60202555
101Endometrial cancer_Homo sapiens_hsa052130.59862256
102Circadian rhythm_Homo sapiens_hsa047100.57762001
103p53 signaling pathway_Homo sapiens_hsa041150.57721376
104GnRH signaling pathway_Homo sapiens_hsa049120.57217389
105Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57039553
106Thyroid cancer_Homo sapiens_hsa052160.56847804
107Viral carcinogenesis_Homo sapiens_hsa052030.56800740
108Bladder cancer_Homo sapiens_hsa052190.56507483
109Melanogenesis_Homo sapiens_hsa049160.56065015
110Glioma_Homo sapiens_hsa052140.55404337
111Ribosome_Homo sapiens_hsa030100.55032917
112Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54302161
113Purine metabolism_Homo sapiens_hsa002300.53348411
114Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.53022093
115Renal cell carcinoma_Homo sapiens_hsa052110.52211096
116Non-homologous end-joining_Homo sapiens_hsa034500.51689661
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51453032
118ErbB signaling pathway_Homo sapiens_hsa040120.51432672
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50691517
120Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50639067
121Epstein-Barr virus infection_Homo sapiens_hsa051690.50421163
122Glutamatergic synapse_Homo sapiens_hsa047240.49920994
123Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.49572736
124Morphine addiction_Homo sapiens_hsa050320.47934085
125Prostate cancer_Homo sapiens_hsa052150.47584769
126Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44853769
127Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.44513390
128Adherens junction_Homo sapiens_hsa045200.44477511
129One carbon pool by folate_Homo sapiens_hsa006700.43863196
130Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43772709
131Base excision repair_Homo sapiens_hsa034100.43090951
132Melanoma_Homo sapiens_hsa052180.43038251
133Cardiac muscle contraction_Homo sapiens_hsa042600.42396401
134Vascular smooth muscle contraction_Homo sapiens_hsa042700.41965111
135Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.41166141
136Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.40873309
137Primary bile acid biosynthesis_Homo sapiens_hsa001200.39090072
138Regulation of autophagy_Homo sapiens_hsa041400.39021997
139Tyrosine metabolism_Homo sapiens_hsa003500.38022351
140Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.36918007
141Fatty acid degradation_Homo sapiens_hsa000710.36268845
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36201396
143Arginine biosynthesis_Homo sapiens_hsa002200.33441186
144Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.32546166

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