MMD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-amino acid import (GO:0043092)6.39372072
2amino acid import (GO:0043090)5.78322834
3C4-dicarboxylate transport (GO:0015740)5.54035793
4axon ensheathment in central nervous system (GO:0032291)5.39730379
5central nervous system myelination (GO:0022010)5.39730379
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.08982536
7neurotransmitter-gated ion channel clustering (GO:0072578)4.42497153
8auditory behavior (GO:0031223)4.39176112
9response to auditory stimulus (GO:0010996)4.33728579
10gamma-aminobutyric acid transport (GO:0015812)4.33668118
11neurotransmitter uptake (GO:0001504)4.11792859
12regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.08150434
13regulation of synaptic vesicle transport (GO:1902803)4.01375153
14low-density lipoprotein particle remodeling (GO:0034374)3.91052735
15cellular potassium ion homeostasis (GO:0030007)3.90758977
16presynaptic membrane assembly (GO:0097105)3.84882276
17negative regulation of astrocyte differentiation (GO:0048712)3.82559553
18neuron cell-cell adhesion (GO:0007158)3.77147928
19acidic amino acid transport (GO:0015800)3.75609550
20negative regulation of synaptic transmission, GABAergic (GO:0032229)3.72756308
21positive regulation of cellular amide metabolic process (GO:0034250)3.69197929
22locomotory exploration behavior (GO:0035641)3.66308961
23L-serine transport (GO:0015825)3.63007277
24alanine transport (GO:0032328)3.61036311
25regulation of beta-amyloid formation (GO:1902003)3.60743913
26neuromuscular process controlling balance (GO:0050885)3.59769688
27cellular response to cholesterol (GO:0071397)3.58858177
28negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.58128065
29oligodendrocyte differentiation (GO:0048709)3.58100186
30positive regulation of dendritic spine development (GO:0060999)3.56464321
31astrocyte differentiation (GO:0048708)3.53919619
32transmission of nerve impulse (GO:0019226)3.53393678
33fatty acid elongation (GO:0030497)3.51226528
34regulation of respiratory system process (GO:0044065)3.50023907
35layer formation in cerebral cortex (GO:0021819)3.49954289
36positive regulation of membrane potential (GO:0045838)3.48557120
37presynaptic membrane organization (GO:0097090)3.46777123
38mechanosensory behavior (GO:0007638)3.45600800
39myelination (GO:0042552)3.41768015
40neurotransmitter transport (GO:0006836)3.41353193
41cell communication by electrical coupling (GO:0010644)3.39957588
42sodium ion export (GO:0071436)3.39219072
43regulation of short-term neuronal synaptic plasticity (GO:0048172)3.37637889
44regulation of neurotransmitter uptake (GO:0051580)3.36860539
45positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.35105314
46regulation of neurotransmitter transport (GO:0051588)3.33572665
47cellular sodium ion homeostasis (GO:0006883)3.33492692
48cerebellar granule cell differentiation (GO:0021707)3.33266556
49regulation of neurotransmitter levels (GO:0001505)3.32752248
50negative regulation of sodium ion transport (GO:0010766)3.32671882
51glutamate receptor signaling pathway (GO:0007215)3.32136117
52photoreceptor cell differentiation (GO:0046530)3.31297178
53eye photoreceptor cell differentiation (GO:0001754)3.31297178
54ionotropic glutamate receptor signaling pathway (GO:0035235)3.30857010
55axon ensheathment (GO:0008366)3.30211631
56ensheathment of neurons (GO:0007272)3.30211631
57L-glutamate transport (GO:0015813)3.28786862
58establishment of mitochondrion localization (GO:0051654)3.28126320
59regulation of neurotransmitter secretion (GO:0046928)3.27955372
60positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.24872028
61cerebral cortex radially oriented cell migration (GO:0021799)3.23775442
62positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.21589464
63membrane assembly (GO:0071709)3.19625919
64regulation of cardiac muscle cell contraction (GO:0086004)3.18837384
65peripheral nervous system axon ensheathment (GO:0032292)3.17985155
66myelination in peripheral nervous system (GO:0022011)3.17985155
67regulation of voltage-gated calcium channel activity (GO:1901385)3.17922410
68regulation of amyloid precursor protein catabolic process (GO:1902991)3.16843315
69G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.16561350
70glial cell proliferation (GO:0014009)3.13655381
71response to gravity (GO:0009629)3.13294751
72regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.12504916
73regulation of excitatory postsynaptic membrane potential (GO:0060079)3.11726760
74positive regulation of synapse maturation (GO:0090129)3.10771410
75vocalization behavior (GO:0071625)3.10640618
76neuronal ion channel clustering (GO:0045161)3.10369606
77regulation of dendritic spine morphogenesis (GO:0061001)3.09149265
78postsynaptic membrane organization (GO:0001941)3.08163341
79regulation of dendritic spine development (GO:0060998)3.07202560
80synaptic transmission, glutamatergic (GO:0035249)3.06379691
81cGMP-mediated signaling (GO:0019934)3.05080220
82serine transport (GO:0032329)3.05076553
83chondroitin sulfate catabolic process (GO:0030207)3.04681450
84synaptic vesicle exocytosis (GO:0016079)3.00724911
85dendritic spine organization (GO:0097061)3.00341981
86glutamate secretion (GO:0014047)2.99900680
87positive regulation of neurotransmitter secretion (GO:0001956)2.97110054
88regulation of neuronal synaptic plasticity (GO:0048168)2.95194767
89regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.94270653
90prepulse inhibition (GO:0060134)2.93413679
91potassium ion import (GO:0010107)2.93362098
92positive regulation of neurotransmitter transport (GO:0051590)2.92669214
93synaptic vesicle endocytosis (GO:0048488)2.92634551
94regulation of postsynaptic membrane potential (GO:0060078)2.90874414
95negative regulation of neurotransmitter transport (GO:0051589)2.90695936
96cellular response to sterol (GO:0036315)2.90690031
97membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.89382239
98regulation of respiratory gaseous exchange (GO:0043576)2.89286512
99cerebellar Purkinje cell layer development (GO:0021680)2.89119787
100detection of calcium ion (GO:0005513)2.87423552
101neuronal action potential propagation (GO:0019227)2.86970430
102protein localization to synapse (GO:0035418)2.86413493
103regulation of astrocyte differentiation (GO:0048710)2.85106262
104regulation of synaptic transmission, glutamatergic (GO:0051966)2.84896652
105synaptic vesicle maturation (GO:0016188)2.82620827
106dendrite morphogenesis (GO:0048813)2.82423608
107regulation of long-term neuronal synaptic plasticity (GO:0048169)2.80500963
108positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.78613098
109cholesterol biosynthetic process (GO:0006695)2.77093746
110atrial cardiac muscle cell action potential (GO:0086014)2.75955792
111regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.75875274
112potassium ion homeostasis (GO:0055075)2.73968173
113negative regulation of protein localization to cell surface (GO:2000009)2.72914169
114regulation of phospholipid biosynthetic process (GO:0071071)2.72446287
115long-term synaptic potentiation (GO:0060291)2.72095830
116cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.69074703
117regulation of glutamate receptor signaling pathway (GO:1900449)2.68868086
118neuron-neuron synaptic transmission (GO:0007270)2.67229523
119exploration behavior (GO:0035640)2.66923172
120gamma-aminobutyric acid signaling pathway (GO:0007214)2.64980304
121regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.60320369
122dermatan sulfate metabolic process (GO:0030205)2.58955293
123neuron recognition (GO:0008038)2.56651268
124astrocyte development (GO:0014002)2.54203719
125regulation of synaptic vesicle exocytosis (GO:2000300)2.53860103
126drinking behavior (GO:0042756)2.53000178
127dendritic spine morphogenesis (GO:0060997)2.51931803
128long-term memory (GO:0007616)2.51735115
129very long-chain fatty acid metabolic process (GO:0000038)2.48721006
130adenine nucleotide transport (GO:0051503)2.48573842
131ovulation cycle (GO:0042698)2.47480876
132dermatan sulfate biosynthetic process (GO:0030208)2.47047870
133glycine transport (GO:0015816)2.46907435
134positive regulation of synapse assembly (GO:0051965)2.46903200
135regulation of synapse structural plasticity (GO:0051823)2.46278117
136regulation of synaptic plasticity (GO:0048167)2.46099057
137neurotransmitter secretion (GO:0007269)2.45954480

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.24853334
2GBX2_23144817_ChIP-Seq_PC3_Human3.54652158
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98588736
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.93596391
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.77631269
6SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.66342664
7AR_21572438_ChIP-Seq_LNCaP_Human2.55387792
8EED_16625203_ChIP-ChIP_MESCs_Mouse2.49291343
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.46588616
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45661716
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.41117491
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.41117491
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.38467857
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.37223938
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.35453368
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.24954740
17RNF2_27304074_Chip-Seq_ESCs_Mouse2.16308101
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.09084013
19EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.05643381
20REST_21632747_ChIP-Seq_MESCs_Mouse2.01326556
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.00732724
22GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.93759082
23SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.83763120
24DROSHA_22980978_ChIP-Seq_HELA_Human1.83625109
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.82281894
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.76928385
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.75359012
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72237005
29RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.69765062
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.67959292
31IKZF1_21737484_ChIP-ChIP_HCT116_Human1.67626906
32RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.65138318
33PIAS1_25552417_ChIP-Seq_VCAP_Human1.60854013
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.58970694
35P300_19829295_ChIP-Seq_ESCs_Human1.58308764
36* RARB_27405468_Chip-Seq_BRAIN_Mouse1.57896825
37RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.53914640
38CDX2_19796622_ChIP-Seq_MESCs_Mouse1.53811758
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.52674071
40OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52092568
41REST_18959480_ChIP-ChIP_MESCs_Mouse1.50563905
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49521521
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.46377384
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42481061
45SMAD4_21799915_ChIP-Seq_A2780_Human1.41525621
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.41452791
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.40667116
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34384913
49DNAJC2_21179169_ChIP-ChIP_NT2_Human1.33845316
50NR3C1_21868756_ChIP-Seq_MCF10A_Human1.33691261
51ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.31464543
52TAF15_26573619_Chip-Seq_HEK293_Human1.30237459
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.30229227
54AR_25329375_ChIP-Seq_VCAP_Human1.28841593
55RING1B_27294783_Chip-Seq_ESCs_Mouse1.27938781
56FUS_26573619_Chip-Seq_HEK293_Human1.27492416
57PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.26760437
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22385305
59AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20410262
60* STAT3_23295773_ChIP-Seq_U87_Human1.18995291
61VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18821808
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.15605068
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.15521145
64TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15497001
65P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13761118
66CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.13526045
67OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.12493251
68NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11389017
69* SOX2_21211035_ChIP-Seq_LN229_Gbm1.11217082
70TRIM28_21343339_ChIP-Seq_HEK293_Human1.10367384
71CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10261578
72EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.10001977
73E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.09984520
74BCAT_22108803_ChIP-Seq_LS180_Human1.09616467
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.08888618
76* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07365581
77* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.07012813
78PRDM14_20953172_ChIP-Seq_ESCs_Human1.06918946
79TP53_18474530_ChIP-ChIP_U2OS_Human1.05140389
80CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.05044944
81VDR_22108803_ChIP-Seq_LS180_Human1.03887245
82WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03660850
83RXR_22108803_ChIP-Seq_LS180_Human1.03425937
84TP53_20018659_ChIP-ChIP_R1E_Mouse1.03373271
85AR_19668381_ChIP-Seq_PC3_Human1.02902435
86RUNX2_22187159_ChIP-Seq_PCA_Human1.01721238
87ZNF274_21170338_ChIP-Seq_K562_Hela1.01347346
88ER_23166858_ChIP-Seq_MCF-7_Human1.01244256
89TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.00608013
90TCF4_23295773_ChIP-Seq_U87_Human1.00363174
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.00251349
92CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99509342
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98677488
94MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98594024
95NANOG_18555785_Chip-Seq_ESCs_Mouse0.98405913
96EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.98288132
97HTT_18923047_ChIP-ChIP_STHdh_Human0.96338002
98RING1B_27294783_Chip-Seq_NPCs_Mouse0.96094560
99IGF1R_20145208_ChIP-Seq_DFB_Human0.95938084
100* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94877998
101RNF2_27304074_Chip-Seq_NSC_Mouse0.94266557
102* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.94170283
103SOX9_26525672_Chip-Seq_HEART_Mouse0.93763482
104* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93460782
105ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93386718
106* GATA1_26923725_Chip-Seq_HPCs_Mouse0.93052316
107EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.92637238
108ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.92524333
109TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91959573
110POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91959573
111MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.91141208
112TP53_16413492_ChIP-PET_HCT116_Human0.90811335
113BMI1_23680149_ChIP-Seq_NPCS_Mouse0.90072730
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.89869763
115KDM2B_26808549_Chip-Seq_K562_Human0.89230277
116SMAD4_21741376_ChIP-Seq_HESCs_Human0.89014343
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.88947414
118FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.88420007
119NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.87335048
120NRF2_20460467_ChIP-Seq_MEFs_Mouse0.87335048
121* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87326014
122* SMAD3_21741376_ChIP-Seq_ESCs_Human0.87283825
123JUN_21703547_ChIP-Seq_K562_Human0.86792363
124SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.86729086
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.84999117
126WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.81835101
127SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.80525407
128RUNX1_26923725_Chip-Seq_HPCs_Mouse0.78841171
129CTNNB1_20460455_ChIP-Seq_HCT116_Human0.78297349
130TET1_21490601_ChIP-Seq_MESCs_Mouse0.77565853

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.08050425
2MP0003880_abnormal_central_pattern3.40089305
3MP0004885_abnormal_endolymph3.34822388
4MP0003136_yellow_coat_color3.27464216
5MP0003690_abnormal_glial_cell3.17319079
6MP0003329_amyloid_beta_deposits3.08244535
7MP0001486_abnormal_startle_reflex2.93827193
8MP0003635_abnormal_synaptic_transmissio2.85154212
9MP0004270_analgesia2.84987674
10MP0009745_abnormal_behavioral_response2.63098736
11MP0004858_abnormal_nervous_system2.53885213
12MP0002064_seizures2.50891859
13MP0005423_abnormal_somatic_nervous2.46141765
14MP0002063_abnormal_learning/memory/cond2.32004240
15MP0005171_absent_coat_pigmentation2.29366665
16MP0005646_abnormal_pituitary_gland2.24718242
17MP0002572_abnormal_emotion/affect_behav2.21434969
18MP0000920_abnormal_myelination2.11827195
19MP0009384_cardiac_valve_regurgitation2.11295253
20MP0002272_abnormal_nervous_system2.11162160
21MP0001440_abnormal_grooming_behavior2.08625431
22MP0001485_abnormal_pinna_reflex2.08120417
23MP0009046_muscle_twitch2.04608270
24MP0003634_abnormal_glial_cell2.02959152
25MP0001968_abnormal_touch/_nociception1.95436544
26MP0002736_abnormal_nociception_after1.95108063
27MP0000778_abnormal_nervous_system1.94860885
28MP0002734_abnormal_mechanical_nocicepti1.91384675
29MP0001502_abnormal_circadian_rhythm1.76365090
30MP0001905_abnormal_dopamine_level1.75834559
31MP0003633_abnormal_nervous_system1.74858536
32MP0001984_abnormal_olfaction1.68564060
33MP0008569_lethality_at_weaning1.66682631
34MP0005551_abnormal_eye_electrophysiolog1.65094170
35MP0000604_amyloidosis1.64969920
36MP0003631_nervous_system_phenotype1.63615594
37MP0002733_abnormal_thermal_nociception1.60038434
38MP0003632_abnormal_nervous_system1.59718629
39MP0005645_abnormal_hypothalamus_physiol1.59458992
40MP0002067_abnormal_sensory_capabilities1.57440450
41MP0003879_abnormal_hair_cell1.57133650
42MP0002254_reproductive_system_inflammat1.56133668
43MP0005377_hearing/vestibular/ear_phenot1.55538928
44MP0003878_abnormal_ear_physiology1.55538928
45MP0002557_abnormal_social/conspecific_i1.53025977
46MP0009780_abnormal_chondrocyte_physiolo1.51442262
47MP0001970_abnormal_pain_threshold1.44718766
48MP0001529_abnormal_vocalization1.44029493
49MP0004742_abnormal_vestibular_system1.43225824
50MP0003075_altered_response_to1.40153576
51MP0004142_abnormal_muscle_tone1.38489751
52MP0001501_abnormal_sleep_pattern1.38112532
53MP0000566_synostosis1.36333686
54MP0002882_abnormal_neuron_morphology1.36100113
55MP0002229_neurodegeneration1.30689136
56MP0001963_abnormal_hearing_physiology1.26703436
57MP0003011_delayed_dark_adaptation1.23489558
58MP0004924_abnormal_behavior1.21250148
59MP0005386_behavior/neurological_phenoty1.21250148
60MP0002066_abnormal_motor_capabilities/c1.19151733
61MP0000955_abnormal_spinal_cord1.18554709
62MP0005167_abnormal_blood-brain_barrier1.15793900
63MP0002735_abnormal_chemical_nociception1.13352676
64MP0005253_abnormal_eye_physiology1.12383328
65MP0000026_abnormal_inner_ear1.11088414
66MP0002638_abnormal_pupillary_reflex1.09495379
67MP0002152_abnormal_brain_morphology1.02656767
68MP0005410_abnormal_fertilization1.01980616
69MP0001986_abnormal_taste_sensitivity1.00972494
70MP0002653_abnormal_ependyma_morphology1.00493989
71MP0005409_darkened_coat_color0.96781452
72MP0002752_abnormal_somatic_nervous0.96289051
73MP0002184_abnormal_innervation0.94022759
74MP0002090_abnormal_vision0.93539863
75MP0001299_abnormal_eye_distance/0.93181573
76MP0002822_catalepsy0.91625112
77MP0003137_abnormal_impulse_conducting0.90339374
78MP0004043_abnormal_pH_regulation0.89069914
79MP0006292_abnormal_olfactory_placode0.88678690
80MP0005623_abnormal_meninges_morphology0.85122574
81MP0001346_abnormal_lacrimal_gland0.83970503
82MP0006072_abnormal_retinal_apoptosis0.83869586
83MP0005195_abnormal_posterior_eye0.81425781
84MP0001177_atelectasis0.79536771
85MP0005332_abnormal_amino_acid0.78755341
86MP0000631_abnormal_neuroendocrine_gland0.77370151
87MP0005595_abnormal_vascular_smooth0.77077400
88MP0006276_abnormal_autonomic_nervous0.76875708
89MP0003122_maternal_imprinting0.76035501
90MP0000049_abnormal_middle_ear0.75809306
91MP0004811_abnormal_neuron_physiology0.75136998
92MP0002089_abnormal_postnatal_growth/wei0.74541155
93MP0002909_abnormal_adrenal_gland0.74112138
94MP0000579_abnormal_nail_morphology0.72978130
95MP0003279_aneurysm0.71096432
96MP0003183_abnormal_peptide_metabolism0.70665500
97MP0000372_irregular_coat_pigmentation0.69791768
98MP0005379_endocrine/exocrine_gland_phen0.68955419
99MP0001664_abnormal_digestion0.66940346
100MP0000647_abnormal_sebaceous_gland0.66050283
101MP0002069_abnormal_eating/drinking_beha0.66021769
102MP0009840_abnormal_foam_cell0.65910280
103MP0004215_abnormal_myocardial_fiber0.65903137
104MP0005499_abnormal_olfactory_system0.62359633
105MP0005394_taste/olfaction_phenotype0.62359633
106MP0003950_abnormal_plasma_membrane0.62281040
107MP0008874_decreased_physiological_sensi0.61082698
108MP0001943_abnormal_respiration0.60733246
109MP0002295_abnormal_pulmonary_circulatio0.60437762
110MP0003787_abnormal_imprinting0.59512604
111MP0003861_abnormal_nervous_system0.59183670
112MP0005647_abnormal_sex_gland0.57942686
113MP0004130_abnormal_muscle_cell0.57463240
114MP0000534_abnormal_ureter_morphology0.54756581
115MP0005535_abnormal_body_temperature0.52393293
116MP0005166_decreased_susceptibility_to0.49897985
117MP0000639_abnormal_adrenal_gland0.49870098
118MP0010769_abnormal_survival0.48799560
119MP0005248_abnormal_Harderian_gland0.46820607
120MP0003956_abnormal_body_size0.46366970
121MP0003172_abnormal_lysosome_physiology0.45971771

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)5.73841017
2Aplasia involving bones of the upper limbs (HP:0009823)5.49894229
3Aplasia of the phalanges of the hand (HP:0009802)5.49894229
4Aplasia involving bones of the extremities (HP:0009825)5.49894229
5Megalencephaly (HP:0001355)5.09026610
6Cerebral inclusion bodies (HP:0100314)4.40683590
7Hemiparesis (HP:0001269)4.38682555
8Focal motor seizures (HP:0011153)4.13146641
9Myokymia (HP:0002411)3.74246915
10Hypoplastic left heart (HP:0004383)3.73210902
11Supranuclear gaze palsy (HP:0000605)3.68064097
12Epileptic encephalopathy (HP:0200134)3.67839339
13Hemiplegia (HP:0002301)3.63837921
14Abnormality of the axillary hair (HP:0100134)3.31522501
15Abnormality of secondary sexual hair (HP:0009888)3.31522501
16Abnormality of binocular vision (HP:0011514)3.21474762
17Diplopia (HP:0000651)3.21474762
18Urinary bladder sphincter dysfunction (HP:0002839)3.17654632
19Humeroradial synostosis (HP:0003041)3.13556326
20Synostosis involving the elbow (HP:0003938)3.13556326
21Clumsiness (HP:0002312)3.11280053
22Hyperventilation (HP:0002883)3.07238541
23Mutism (HP:0002300)3.05926011
24Hypoplastic heart (HP:0001961)2.93549337
25Delusions (HP:0000746)2.89843727
26Limb dystonia (HP:0002451)2.88024110
27Split foot (HP:0001839)2.84854402
28Hypoplastic pelvis (HP:0008839)2.83532860
29Degeneration of the lateral corticospinal tracts (HP:0002314)2.75678388
30Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.75678388
31Spastic tetraparesis (HP:0001285)2.70884620
32Focal seizures (HP:0007359)2.66908882
33Impaired vibration sensation in the lower limbs (HP:0002166)2.63505459
34Action tremor (HP:0002345)2.63432521
35Truncal ataxia (HP:0002078)2.59911038
36Dysmetria (HP:0001310)2.57212720
37Urinary urgency (HP:0000012)2.56407682
38Ankle clonus (HP:0011448)2.55277415
39Morphological abnormality of the inner ear (HP:0011390)2.54798424
40Dysdiadochokinesis (HP:0002075)2.53501740
41Decreased central vision (HP:0007663)2.52980318
42Parakeratosis (HP:0001036)2.52700460
43Torticollis (HP:0000473)2.51435802
44Obstructive sleep apnea (HP:0002870)2.44653410
45Mixed hearing impairment (HP:0000410)2.42949425
46Progressive cerebellar ataxia (HP:0002073)2.42852828
47Poor eye contact (HP:0000817)2.42304421
48Intention tremor (HP:0002080)2.41514171
49Oligodactyly (hands) (HP:0001180)2.40093373
50Abnormality of the corticospinal tract (HP:0002492)2.36257792
51Tetraplegia (HP:0002445)2.36246919
52Absence seizures (HP:0002121)2.32956681
53Stereotypic behavior (HP:0000733)2.30800122
54Spastic gait (HP:0002064)2.30488644
55Sensorimotor neuropathy (HP:0007141)2.27560216
56Paraparesis (HP:0002385)2.25562273
57Bowel incontinence (HP:0002607)2.21085783
58Neuronal loss in central nervous system (HP:0002529)2.19060211
59Generalized tonic-clonic seizures (HP:0002069)2.18874383
60Spastic paraparesis (HP:0002313)2.18236879
61Long nose (HP:0003189)2.17978610
62Abnormality of the middle phalanges of the toes (HP:0010183)2.16586187
63Myelomeningocele (HP:0002475)2.15858185
64Bradykinesia (HP:0002067)2.13838545
65Abnormal auditory evoked potentials (HP:0006958)2.13091006
66Clonus (HP:0002169)2.12167599
67Abnormal eating behavior (HP:0100738)2.11889113
68Lower limb muscle weakness (HP:0007340)2.11658029
69Scanning speech (HP:0002168)2.11485094
70Visual hallucinations (HP:0002367)2.11326430
71Atonic seizures (HP:0010819)2.09739107
72Annular pancreas (HP:0001734)2.05865774
73Abnormal social behavior (HP:0012433)2.05020756
74Impaired social interactions (HP:0000735)2.05020756
75Fibular aplasia (HP:0002990)2.04804807
76Hypoplasia of the corpus callosum (HP:0002079)2.02954883
77Anomalous pulmonary venous return (HP:0010772)2.02907112
78Retinal dysplasia (HP:0007973)2.02541426
79Morphological abnormality of the pyramidal tract (HP:0002062)2.02191042
80Focal dystonia (HP:0004373)2.01897494
81Confusion (HP:0001289)2.01024930
82Axonal loss (HP:0003447)1.99670335
83Postural instability (HP:0002172)1.98214278
84Back pain (HP:0003418)1.98110233
85Methylmalonic acidemia (HP:0002912)1.97994222
86Abnormality of the dental pulp (HP:0006479)1.97850703
87Abnormality of cochlea (HP:0000375)1.97692318
88Abnormal large intestine physiology (HP:0012700)1.97453764
89Peripheral hypomyelination (HP:0007182)1.97149552
90Pheochromocytoma (HP:0002666)1.94935323
91Akinesia (HP:0002304)1.94620077
92Papilledema (HP:0001085)1.94100028
93Absent hair (HP:0002298)1.93811209
94Sleep apnea (HP:0010535)1.92231595
95Cerebral hypomyelination (HP:0006808)1.91530818
96Thickened helices (HP:0000391)1.90820550
97Short hallux (HP:0010109)1.90595668
98Narrow nasal bridge (HP:0000446)1.90128111
99Facial shape deformation (HP:0011334)1.90106479
100Potter facies (HP:0002009)1.90106479
101Truncus arteriosus (HP:0001660)1.90019030
102Large for gestational age (HP:0001520)1.88847942
103Increased circulating renin level (HP:0000848)1.88455629
104Symphalangism affecting the phalanges of the hand (HP:0009773)1.88081060
105Blue irides (HP:0000635)1.87849305
106Coronal craniosynostosis (HP:0004440)1.87323124
107Apathy (HP:0000741)1.85829251
108Depression (HP:0000716)1.85384058
109Craniofacial dystonia (HP:0012179)1.84852413
110Impaired vibratory sensation (HP:0002495)1.83987638
111Broad-based gait (HP:0002136)1.82133258
112Abnormality of permanent molar morphology (HP:0011071)1.81819984
113Abnormality of the dental root (HP:0006486)1.81819984
114Taurodontia (HP:0000679)1.81819984
115EEG with generalized epileptiform discharges (HP:0011198)1.81801552
116Anxiety (HP:0000739)1.79852663
117Abnormality of the diencephalon (HP:0010662)1.78988908
118Dialeptic seizures (HP:0011146)1.78237476
119Abnormality of molar (HP:0011077)1.78108416
120Abnormality of molar morphology (HP:0011070)1.78108416
121Meningocele (HP:0002435)1.77409004
122Brittle hair (HP:0002299)1.77240352
123Abnormality of glycine metabolism (HP:0010895)1.77136400
124Abnormality of serine family amino acid metabolism (HP:0010894)1.77136400
125Polyphagia (HP:0002591)1.76606169
126Alacrima (HP:0000522)1.76327825
127Gait imbalance (HP:0002141)1.75668318
128Sensory axonal neuropathy (HP:0003390)1.75577279
129Generalized myoclonic seizures (HP:0002123)1.75096916
130Slow saccadic eye movements (HP:0000514)1.74484604
131Excessive salivation (HP:0003781)1.74462380
132Drooling (HP:0002307)1.74462380
133Febrile seizures (HP:0002373)1.74266166
134Hypsarrhythmia (HP:0002521)1.73540682
135Status epilepticus (HP:0002133)1.73248904
136Medial flaring of the eyebrow (HP:0010747)1.73150692
137Broad alveolar ridges (HP:0000187)1.72863729
138Lower limb asymmetry (HP:0100559)1.71167452
139Congenital malformation of the right heart (HP:0011723)1.70876114
140Double outlet right ventricle (HP:0001719)1.70876114
141Amyotrophic lateral sclerosis (HP:0007354)1.70287915
142Anteriorly placed anus (HP:0001545)1.70273870
143CNS hypomyelination (HP:0003429)1.69917986
144Abnormality of the pulmonary veins (HP:0011718)1.69342987
145Epileptiform EEG discharges (HP:0011182)1.68709700
146Neuroendocrine neoplasm (HP:0100634)1.67805131
147Metabolic alkalosis (HP:0200114)1.67798871
148Absent septum pellucidum (HP:0001331)1.67790296

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.78392555
2TNIK3.90750040
3CASK3.59504459
4MUSK3.21780780
5LMTK22.96414465
6PHKG22.79428550
7PHKG12.79428550
8NTRK32.72909688
9NTRK22.67991003
10PRPF4B2.48045317
11STK392.33378848
12PRKD32.27502292
13MARK12.07845860
14OXSR11.99047673
15MAPK131.79240972
16MAP2K71.69303625
17SGK4941.52917987
18SGK2231.52917987
19NTRK11.50452943
20PAK61.49051727
21FGR1.47215313
22MAP3K41.38510891
23MINK11.37859626
24CDK51.22603430
25TYRO31.19777974
26MAP3K91.18718225
27CSNK1A1L1.12766821
28PRKCG1.11382669
29SGK21.08421907
30PKN11.06765130
31CDK191.06059857
32CAMK2A1.03692509
33NEK61.02292450
34PLK21.01548432
35EPHB10.99944581
36MAPK120.99084740
37ROCK20.95685215
38KSR20.95399387
39PAK30.93675536
40PBK0.92507023
41FGFR20.91783854
42CAMK10.91618072
43CAMK2B0.91301818
44PRKCE0.91065573
45DAPK20.89177795
46DYRK1A0.85775156
47FES0.85128916
48BCR0.84951118
49UHMK10.81770212
50SIK20.77664048
51KSR10.75532963
52WNK40.75483896
53PINK10.75141627
54CSNK1G20.74522636
55SGK10.73283216
56DAPK10.72550156
57CAMK2G0.71452935
58RIPK40.71209274
59MAPK70.70710507
60SGK30.70197443
61DYRK20.68651968
62CDK150.68448285
63WNK10.68443051
64CDK180.67984713
65NEK90.66623594
66CAMKK20.65994361
67MAPK100.65991243
68PTK2B0.65901742
69CDK140.65830682
70CAMK2D0.65460880
71RET0.64929886
72BCKDK0.64898830
73PRKCQ0.63702356
74ARAF0.63515727
75MET0.63472996
76BMPR20.63240026
77GRK50.62899096
78ICK0.61820271
79MAP3K130.61813841
80BMX0.61667178
81MAPKAPK50.61168647
82IRAK20.60777023
83PRKCH0.59877352
84RIPK10.59635200
85CDK11A0.58697237
86PNCK0.57938216
87ERBB40.57747735
88ERBB20.56193931
89CAMK40.55914740
90SIK10.55795492
91CCNB10.55312901
92CDK30.53668005
93RAF10.53197563
94ROCK10.52789257
95MARK20.51562181
96MKNK20.51029054
97ADRBK10.50385916
98FYN0.48783021
99RPS6KB10.48653658
100PRKD20.48628075
101MAP2K40.47974191
102MAPK150.47643791
103ALK0.47078645
104PRKACA0.44146181
105PRKG10.43690535
106CAMKK10.43610559
107TNK20.43605230
108LIMK10.43426608
109MAP3K20.42698559
110PDPK10.42420803
111WNK30.41851120
112MST40.41764586
113CSNK1G10.41464140
114CSNK1D0.41166002
115PRKCA0.40582375
116PRKCZ0.40221421
117CSNK1A10.40068665
118RPS6KA30.40043672
119GRK60.39448220
120ADRBK20.38489294
121ERBB30.37035223
122CSNK1G30.36156372
123AKT20.35870643
124STK110.35589865
125PIK3CA0.33833809
126MOS0.31047433

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009104.21820027
2Steroid biosynthesis_Homo sapiens_hsa001003.33703988
3Fatty acid biosynthesis_Homo sapiens_hsa000613.12003279
4Nicotine addiction_Homo sapiens_hsa050332.82548880
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.49260936
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.48646155
7Glutamatergic synapse_Homo sapiens_hsa047242.34321670
8Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.24315180
9Fatty acid elongation_Homo sapiens_hsa000622.23682814
10GABAergic synapse_Homo sapiens_hsa047272.22651598
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.19577143
12Fatty acid metabolism_Homo sapiens_hsa012122.07149184
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.87599083
14Morphine addiction_Homo sapiens_hsa050321.85534403
15Circadian entrainment_Homo sapiens_hsa047131.75641787
16Ether lipid metabolism_Homo sapiens_hsa005651.73523058
17Salivary secretion_Homo sapiens_hsa049701.67414373
18Olfactory transduction_Homo sapiens_hsa047401.52187870
19Synaptic vesicle cycle_Homo sapiens_hsa047211.44729891
20Butanoate metabolism_Homo sapiens_hsa006501.41249901
21Gastric acid secretion_Homo sapiens_hsa049711.41096546
22Fatty acid degradation_Homo sapiens_hsa000711.40480927
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.33221627
24Insulin secretion_Homo sapiens_hsa049111.31752116
25Serotonergic synapse_Homo sapiens_hsa047261.29720120
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29199863
27Long-term potentiation_Homo sapiens_hsa047201.27530126
28Cocaine addiction_Homo sapiens_hsa050301.20934358
29Amphetamine addiction_Homo sapiens_hsa050311.19703095
30Propanoate metabolism_Homo sapiens_hsa006401.17449276
31Renin secretion_Homo sapiens_hsa049241.16146390
32Axon guidance_Homo sapiens_hsa043601.14930827
33Calcium signaling pathway_Homo sapiens_hsa040201.13526201
34Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08170012
35Sulfur metabolism_Homo sapiens_hsa009201.08158239
36Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.07827179
37Long-term depression_Homo sapiens_hsa047301.06624390
38Estrogen signaling pathway_Homo sapiens_hsa049151.05745916
39Dopaminergic synapse_Homo sapiens_hsa047281.04780987
40Taste transduction_Homo sapiens_hsa047421.01872037
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01090621
42Cholinergic synapse_Homo sapiens_hsa047251.00795374
43Glioma_Homo sapiens_hsa052140.95454716
44Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.94495980
45PPAR signaling pathway_Homo sapiens_hsa033200.93536043
46Bile secretion_Homo sapiens_hsa049760.91572625
47beta-Alanine metabolism_Homo sapiens_hsa004100.86300562
48Prion diseases_Homo sapiens_hsa050200.85301094
49Sphingolipid metabolism_Homo sapiens_hsa006000.84690923
50Glycerophospholipid metabolism_Homo sapiens_hsa005640.84683161
51cAMP signaling pathway_Homo sapiens_hsa040240.83592716
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82856546
53Vitamin B6 metabolism_Homo sapiens_hsa007500.82261333
54Dorso-ventral axis formation_Homo sapiens_hsa043200.81885522
55alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.80888956
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.78262681
57Pancreatic secretion_Homo sapiens_hsa049720.77803665
58Peroxisome_Homo sapiens_hsa041460.77493315
59Gap junction_Homo sapiens_hsa045400.75675155
60Mineral absorption_Homo sapiens_hsa049780.75127427
61Melanogenesis_Homo sapiens_hsa049160.74959391
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.74497202
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.73922920
64Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73382730
65Sulfur relay system_Homo sapiens_hsa041220.73268860
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72475484
67Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.71530476
68Oocyte meiosis_Homo sapiens_hsa041140.67872009
69Circadian rhythm_Homo sapiens_hsa047100.67602204
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66940261
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66454176
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.66269842
73Phototransduction_Homo sapiens_hsa047440.65729679
74Arginine and proline metabolism_Homo sapiens_hsa003300.65618603
75Cardiac muscle contraction_Homo sapiens_hsa042600.64816907
76Histidine metabolism_Homo sapiens_hsa003400.63741427
77Folate biosynthesis_Homo sapiens_hsa007900.63263735
78Collecting duct acid secretion_Homo sapiens_hsa049660.62476104
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61193001
80Oxytocin signaling pathway_Homo sapiens_hsa049210.61077384
81Oxidative phosphorylation_Homo sapiens_hsa001900.60381128
82Alzheimers disease_Homo sapiens_hsa050100.60047061
83Glycerolipid metabolism_Homo sapiens_hsa005610.58979432
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56726183
852-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.55741418
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.55550774
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.55525004
88GnRH signaling pathway_Homo sapiens_hsa049120.55482492
89Vibrio cholerae infection_Homo sapiens_hsa051100.53717685
90Rap1 signaling pathway_Homo sapiens_hsa040150.52589357
91African trypanosomiasis_Homo sapiens_hsa051430.52249380
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.52010219
93Hippo signaling pathway_Homo sapiens_hsa043900.51593982
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.50573084
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.49896008
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48606737
97Vitamin digestion and absorption_Homo sapiens_hsa049770.48536392
98Linoleic acid metabolism_Homo sapiens_hsa005910.48364530
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47468349
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.47242673
101ErbB signaling pathway_Homo sapiens_hsa040120.46058536
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45385977
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44708198
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43370735
105Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42616250
106Choline metabolism in cancer_Homo sapiens_hsa052310.42250767
107Alcoholism_Homo sapiens_hsa050340.41234307
108Ras signaling pathway_Homo sapiens_hsa040140.41088075
109Thyroid hormone synthesis_Homo sapiens_hsa049180.40207613
110Wnt signaling pathway_Homo sapiens_hsa043100.40092189
111Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.39737084
112Endocytosis_Homo sapiens_hsa041440.37510894
113Biosynthesis of amino acids_Homo sapiens_hsa012300.37048298
114Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36493878
115Ovarian steroidogenesis_Homo sapiens_hsa049130.35449138
116Basal cell carcinoma_Homo sapiens_hsa052170.35182086
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.35099525
118Hedgehog signaling pathway_Homo sapiens_hsa043400.34436793
119Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33811702
120Pyruvate metabolism_Homo sapiens_hsa006200.33329373
121Inositol phosphate metabolism_Homo sapiens_hsa005620.32546075
122AMPK signaling pathway_Homo sapiens_hsa041520.31643741

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