MIF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.36529120
2viral transcription (GO:0019083)6.27251308
3translational termination (GO:0006415)6.08884756
4ribosomal small subunit biogenesis (GO:0042274)5.85702649
5maturation of SSU-rRNA (GO:0030490)5.57401206
6translational elongation (GO:0006414)5.44527928
7chaperone-mediated protein transport (GO:0072321)5.31855349
8DNA deamination (GO:0045006)5.31550743
9establishment of integrated proviral latency (GO:0075713)5.29508686
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.19294896
11cotranslational protein targeting to membrane (GO:0006613)5.10077514
12protein targeting to ER (GO:0045047)5.07206634
13translational initiation (GO:0006413)4.94484187
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.88308665
15cellular protein complex disassembly (GO:0043624)4.88157440
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.87984083
17mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.84740124
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.81749900
19viral life cycle (GO:0019058)4.79981100
20respiratory electron transport chain (GO:0022904)4.78550213
21protein localization to endoplasmic reticulum (GO:0070972)4.75421812
22DNA strand elongation involved in DNA replication (GO:0006271)4.71342713
23ribosomal large subunit biogenesis (GO:0042273)4.69922336
24electron transport chain (GO:0022900)4.67187666
25pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.54704445
26telomere maintenance via semi-conservative replication (GO:0032201)4.51864646
27protein complex biogenesis (GO:0070271)4.50405845
28energy coupled proton transport, down electrochemical gradient (GO:0015985)4.47795916
29ATP synthesis coupled proton transport (GO:0015986)4.47795916
30DNA strand elongation (GO:0022616)4.47105707
31formation of translation preinitiation complex (GO:0001731)4.45936888
32protein complex disassembly (GO:0043241)4.40679925
33DNA unwinding involved in DNA replication (GO:0006268)4.36699048
34mitochondrial respiratory chain complex assembly (GO:0033108)4.33775444
35spliceosomal snRNP assembly (GO:0000387)4.31842020
36mitochondrial respiratory chain complex I assembly (GO:0032981)4.27902834
37NADH dehydrogenase complex assembly (GO:0010257)4.27902834
38mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.27902834
39ribonucleoprotein complex biogenesis (GO:0022613)4.27480992
40DNA replication initiation (GO:0006270)4.25499312
41macromolecular complex disassembly (GO:0032984)4.17110881
42translation (GO:0006412)4.13983675
43protein maturation by protein folding (GO:0022417)4.07409183
44establishment of viral latency (GO:0019043)4.07107474
45protein targeting to mitochondrion (GO:0006626)4.05671293
46deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.04336674
47nucleobase biosynthetic process (GO:0046112)4.00003232
48pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.92444417
49spliceosomal complex assembly (GO:0000245)3.87865987
50proteasome assembly (GO:0043248)3.86468378
51telomere maintenance via recombination (GO:0000722)3.85894368
52guanosine-containing compound biosynthetic process (GO:1901070)3.85630657
53establishment of protein localization to mitochondrion (GO:0072655)3.82283852
54pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.82270870
55rRNA processing (GO:0006364)3.81075269
56nuclear-transcribed mRNA catabolic process (GO:0000956)3.79214873
57regulation of cellular amino acid metabolic process (GO:0006521)3.78053829
58pyrimidine nucleotide catabolic process (GO:0006244)3.73850776
59pseudouridine synthesis (GO:0001522)3.71500522
60negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.67794961
61rRNA metabolic process (GO:0016072)3.65201121
62protein localization to mitochondrion (GO:0070585)3.64445555
63base-excision repair, AP site formation (GO:0006285)3.62648526
64deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.61082132
65establishment of protein localization to mitochondrial membrane (GO:0090151)3.60745108
66cellular component biogenesis (GO:0044085)3.57442714
67mRNA catabolic process (GO:0006402)3.57235427
682-deoxyribonucleotide biosynthetic process (GO:0009265)3.56095408
69deoxyribose phosphate biosynthetic process (GO:0046385)3.56095408
70ribosome biogenesis (GO:0042254)3.56082778
71transcription elongation from RNA polymerase III promoter (GO:0006385)3.55894459
72termination of RNA polymerase III transcription (GO:0006386)3.55894459
73telomere maintenance via telomere lengthening (GO:0010833)3.55808258
74purine nucleobase biosynthetic process (GO:0009113)3.54977148
75mitotic recombination (GO:0006312)3.52788238
76exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.52701254
77nucleotide-excision repair, DNA gap filling (GO:0006297)3.52276019
78iron-sulfur cluster assembly (GO:0016226)3.51057440
79metallo-sulfur cluster assembly (GO:0031163)3.51057440
80folic acid-containing compound biosynthetic process (GO:0009396)3.49562982
81CTP biosynthetic process (GO:0006241)3.49061582
82CTP metabolic process (GO:0046036)3.49061582
83deoxyribonucleotide catabolic process (GO:0009264)3.48730723
84UTP metabolic process (GO:0046051)3.48628316
85transcription-coupled nucleotide-excision repair (GO:0006283)3.47800736
86purine nucleoside triphosphate biosynthetic process (GO:0009145)3.46872469
87purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.46420622
88nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.43935529
89RNA catabolic process (GO:0006401)3.43622504
90IMP biosynthetic process (GO:0006188)3.42588665
91anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.41108794
92negative regulation of ligase activity (GO:0051352)3.40150931
93negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.40150931
94positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.38949001
95regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.38940001
96pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.38581785
97DNA replication checkpoint (GO:0000076)3.37490226
98peptidyl-arginine omega-N-methylation (GO:0035247)3.36205908
99DNA damage response, detection of DNA damage (GO:0042769)3.34625619
100signal transduction involved in cell cycle checkpoint (GO:0072395)3.33782641
101CENP-A containing nucleosome assembly (GO:0034080)3.33377400
102ribonucleoside triphosphate biosynthetic process (GO:0009201)3.32093211
103histone arginine methylation (GO:0034969)3.31087423
104positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.30395298
105RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.30134694
106tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.30134694
107deoxyribose phosphate catabolic process (GO:0046386)3.29243280
108ATP biosynthetic process (GO:0006754)3.29019676
109protein targeting to membrane (GO:0006612)3.28205286
110regulation of mitochondrial translation (GO:0070129)3.26965615
111chromatin remodeling at centromere (GO:0031055)3.26823832
112respiratory chain complex IV assembly (GO:0008535)3.26395904
113cytochrome complex assembly (GO:0017004)3.24392690
114UTP biosynthetic process (GO:0006228)3.24330740
115cullin deneddylation (GO:0010388)3.24027049
116DNA replication-dependent nucleosome assembly (GO:0006335)3.22838864
117DNA replication-dependent nucleosome organization (GO:0034723)3.22838864
118oxidative phosphorylation (GO:0006119)3.21918305
119viral mRNA export from host cell nucleus (GO:0046784)3.21020656
120DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.20687304
121kinetochore assembly (GO:0051382)3.20357124
122nucleobase-containing small molecule interconversion (GO:0015949)3.20256663
123pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.19283010
124rRNA modification (GO:0000154)3.18263247
1252-deoxyribonucleotide metabolic process (GO:0009394)3.17399554
1267-methylguanosine mRNA capping (GO:0006370)3.16668823
127ribosome assembly (GO:0042255)3.15835654
128intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.15033741
129signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.15033741
130kinetochore organization (GO:0051383)3.12793608
131RNA capping (GO:0036260)3.12098960
1327-methylguanosine RNA capping (GO:0009452)3.12098960
133deoxyribonucleotide biosynthetic process (GO:0009263)3.12035025
134signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.10641966
135signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.10641966
136signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.10641966
137protein localization to kinetochore (GO:0034501)3.09794248
138protein deneddylation (GO:0000338)3.06893278
139mitotic metaphase plate congression (GO:0007080)3.06434783
140signal transduction involved in DNA integrity checkpoint (GO:0072401)3.06000884
141signal transduction involved in DNA damage checkpoint (GO:0072422)3.06000884
142GTP biosynthetic process (GO:0006183)3.05271844
143regulation of protein heterodimerization activity (GO:0043497)3.04935554

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.91098357
2* MYC_18555785_ChIP-Seq_MESCs_Mouse5.03227477
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.43875600
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.74495626
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.62309912
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.51876886
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.36384852
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.33742218
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.27007338
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.25932377
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.21896808
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.20140291
13E2F4_17652178_ChIP-ChIP_JURKAT_Human3.14861906
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.99761384
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.97228212
16XRN2_22483619_ChIP-Seq_HELA_Human2.83729517
17* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.69489961
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.66222122
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.62689442
20NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.59700065
21* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.44911725
22* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.33107702
23THAP11_20581084_ChIP-Seq_MESCs_Mouse2.30833113
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30537450
25VDR_23849224_ChIP-Seq_CD4+_Human2.25999645
26TTF2_22483619_ChIP-Seq_HELA_Human2.20791635
27DCP1A_22483619_ChIP-Seq_HELA_Human2.17395351
28ELF1_17652178_ChIP-ChIP_JURKAT_Human2.01537130
29FOXP3_21729870_ChIP-Seq_TREG_Human1.97308501
30* GABP_19822575_ChIP-Seq_HepG2_Human1.95847258
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.92414379
32* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89769356
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.87664747
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82655611
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80994607
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80188998
37NANOG_18555785_ChIP-Seq_MESCs_Mouse1.78852139
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.78367960
39ELK1_19687146_ChIP-ChIP_HELA_Human1.68908827
40SRF_21415370_ChIP-Seq_HL-1_Mouse1.68565891
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.66622106
42PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.66464608
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64501752
44ZFX_18555785_ChIP-Seq_MESCs_Mouse1.61593808
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61452515
46POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.57999963
47CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.54354357
48AR_21909140_ChIP-Seq_LNCAP_Human1.53202935
49ZNF263_19887448_ChIP-Seq_K562_Human1.52854227
50* E2F1_21310950_ChIP-Seq_MCF-7_Human1.51519403
51SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.50965784
52CIITA_25753668_ChIP-Seq_RAJI_Human1.50668138
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47077103
54* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.44909336
55PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.44321004
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.42408668
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.42202027
58* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.40843503
59TET1_21451524_ChIP-Seq_MESCs_Mouse1.39926695
60MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.35660541
61SOX2_18555785_ChIP-Seq_MESCs_Mouse1.32786154
62* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.32222885
63HOXB4_20404135_ChIP-ChIP_EML_Mouse1.31121563
64ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.29446555
65MYC_18940864_ChIP-ChIP_HL60_Human1.25213663
66CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.24499816
67RBPJ_22232070_ChIP-Seq_NCS_Mouse1.23936548
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.22564667
69KDM5A_27292631_Chip-Seq_BREAST_Human1.22032281
70SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.21662298
71STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18471666
72ELK1_22589737_ChIP-Seq_MCF10A_Human1.16830150
73DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.16789950
74TP63_19390658_ChIP-ChIP_HaCaT_Human1.15788118
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13813415
76MYC_22102868_ChIP-Seq_BL_Human1.13426475
77DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13334216
78CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.13049699
79BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11910109
80ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11337974
81ESR1_15608294_ChIP-ChIP_MCF-7_Human1.10347477
82CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.09886458
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.09394697
84KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07438221
85* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.05603179
86* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04139015
87PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03134780
88ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02659107
89TCF3_18692474_ChIP-Seq_MEFs_Mouse1.01840208
90P68_20966046_ChIP-Seq_HELA_Human1.01568561
91CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01349934
92HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.00379725
93CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.00235117
94E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99669341
95ELF1_20517297_ChIP-Seq_JURKAT_Human0.99463728
96* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.98750860
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97828426
98SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96463969
99CTCF_26484167_Chip-Seq_Bcells_Mouse0.96398079
100* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.95952371
101SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95345699
102BCL6_27268052_Chip-Seq_Bcells_Human0.95220239
103SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.94713592
104KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.93827572
105TFEB_21752829_ChIP-Seq_HELA_Human0.92058598
106SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.91716210
107LXR_22292898_ChIP-Seq_THP-1_Human0.89988846
108CTCF_18555785_ChIP-Seq_MESCs_Mouse0.89934975
109VDR_21846776_ChIP-Seq_THP-1_Human0.88267323
110TBX5_21415370_ChIP-Seq_HL-1_Mouse0.87662256
111EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.86973100
112NOTCH1_21737748_ChIP-Seq_TLL_Human0.86093791
113SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.85846289
114GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.84648793
115FOXP1_21924763_ChIP-Seq_HESCs_Human0.82974097
116* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79321406
117YY1_22570637_ChIP-Seq_MALME-3M_Human0.79311226
118NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.78625028

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.91650135
2MP0004957_abnormal_blastocyst_morpholog4.56892890
3MP0010094_abnormal_chromosome_stability4.10610649
4MP0003111_abnormal_nucleus_morphology3.80447834
5* MP0003077_abnormal_cell_cycle3.68834485
6MP0008057_abnormal_DNA_replication3.41343937
7MP0003123_paternal_imprinting3.39536332
8MP0008932_abnormal_embryonic_tissue3.17283741
9MP0008058_abnormal_DNA_repair2.96829736
10MP0009379_abnormal_foot_pigmentation2.96019856
11MP0008007_abnormal_cellular_replicative2.82733367
12MP0010030_abnormal_orbit_morphology2.63361106
13MP0004133_heterotaxia2.43380014
14MP0001730_embryonic_growth_arrest2.35723468
15MP0002234_abnormal_pharynx_morphology2.15337465
16MP0008877_abnormal_DNA_methylation2.07068639
17* MP0000350_abnormal_cell_proliferation1.95112565
18MP0002163_abnormal_gland_morphology1.88372106
19MP0003786_premature_aging1.86862654
20MP0003121_genomic_imprinting1.85857507
21MP0000537_abnormal_urethra_morphology1.80423755
22MP0001697_abnormal_embryo_size1.77159068
23MP0003890_abnormal_embryonic-extraembry1.69879304
24MP0003315_abnormal_perineum_morphology1.66332742
25MP0006292_abnormal_olfactory_placode1.62366911
26MP0003122_maternal_imprinting1.61823197
27MP0001672_abnormal_embryogenesis/_devel1.60488866
28MP0005380_embryogenesis_phenotype1.60488866
29MP0003806_abnormal_nucleotide_metabolis1.60388314
30MP0003567_abnormal_fetal_cardiomyocyte1.59346080
31MP0001293_anophthalmia1.56094490
32MP0002080_prenatal_lethality1.54978231
33MP0002653_abnormal_ependyma_morphology1.53582257
34MP0001529_abnormal_vocalization1.53509787
35MP0001905_abnormal_dopamine_level1.51790760
36MP0006035_abnormal_mitochondrial_morpho1.51659240
37MP0002085_abnormal_embryonic_tissue1.50655831
38MP0009697_abnormal_copulation1.50062413
39MP0002396_abnormal_hematopoietic_system1.46351155
40MP0003984_embryonic_growth_retardation1.45655738
41MP0003119_abnormal_digestive_system1.45599702
42MP0000313_abnormal_cell_death1.44447558
43MP0002736_abnormal_nociception_after1.43926691
44MP0002088_abnormal_embryonic_growth/wei1.43313037
45MP0003718_maternal_effect1.39024058
46MP0005645_abnormal_hypothalamus_physiol1.33594701
47MP0006036_abnormal_mitochondrial_physio1.31454292
48MP0002160_abnormal_reproductive_system1.31326899
49MP0003186_abnormal_redox_activity1.30538887
50MP0002084_abnormal_developmental_patter1.30003402
51MP0004197_abnormal_fetal_growth/weight/1.28910783
52MP0002938_white_spotting1.28804915
53MP0008995_early_reproductive_senescence1.25497890
54MP0010352_gastrointestinal_tract_polyps1.22919802
55MP0000049_abnormal_middle_ear1.18242754
56MP0002822_catalepsy1.17454020
57MP0001764_abnormal_homeostasis1.16719714
58MP0001346_abnormal_lacrimal_gland1.16456499
59MP0000358_abnormal_cell_content/1.16283475
60MP0000750_abnormal_muscle_regeneration1.14956770
61MP0000566_synostosis1.13958090
62MP0000490_abnormal_crypts_of1.12458901
63MP0009053_abnormal_anal_canal1.10321625
64MP0008789_abnormal_olfactory_epithelium1.06093881
65MP0002086_abnormal_extraembryonic_tissu1.05619777
66MP0002102_abnormal_ear_morphology1.05289142
67MP0002111_abnormal_tail_morphology1.02246456
68MP0005670_abnormal_white_adipose1.02219266
69MP0002751_abnormal_autonomic_nervous1.01826469
70MP0009672_abnormal_birth_weight1.01409331
71MP0003136_yellow_coat_color1.01072560
72MP0005075_abnormal_melanosome_morpholog1.00222047
73MP0004147_increased_porphyrin_level0.99724012
74MP0002132_abnormal_respiratory_system0.98372264
75MP0003942_abnormal_urinary_system0.98143489
76* MP0002019_abnormal_tumor_incidence0.97574030
77MP0009333_abnormal_splenocyte_physiolog0.94460119
78MP0008875_abnormal_xenobiotic_pharmacok0.92688760
79MP0001881_abnormal_mammary_gland0.92105630
80MP0005501_abnormal_skin_physiology0.91052106
81MP0000372_irregular_coat_pigmentation0.88748747
82MP0003941_abnormal_skin_development0.88318622
83MP0003221_abnormal_cardiomyocyte_apopto0.87935545
84MP0001727_abnormal_embryo_implantation0.87760249
85MP0004084_abnormal_cardiac_muscle0.86890130
86MP0002210_abnormal_sex_determination0.85923113
87MP0000678_abnormal_parathyroid_gland0.85130475
88MP0005084_abnormal_gallbladder_morpholo0.84928741
89MP0005389_reproductive_system_phenotype0.84177510
90MP0004808_abnormal_hematopoietic_stem0.82576678
91MP0001968_abnormal_touch/_nociception0.82322348
92MP0005330_cardiomyopathy0.82244061
93MP0003938_abnormal_ear_development0.81960003
94MP0001145_abnormal_male_reproductive0.81155796
95MP0005379_endocrine/exocrine_gland_phen0.79978859
96MP0010307_abnormal_tumor_latency0.79649478
97MP0001286_abnormal_eye_development0.79637428
98MP0001853_heart_inflammation0.79324780
99MP0004858_abnormal_nervous_system0.79176915
100MP0002177_abnormal_outer_ear0.79130011
101MP0005266_abnormal_metabolism0.79031911
102MP0005394_taste/olfaction_phenotype0.78893124
103MP0005499_abnormal_olfactory_system0.78893124
104MP0002249_abnormal_larynx_morphology0.78845436
105MP0000703_abnormal_thymus_morphology0.77517605
106MP0002282_abnormal_trachea_morphology0.76618530
107MP0005646_abnormal_pituitary_gland0.75676826
108MP0000631_abnormal_neuroendocrine_gland0.74410791
109MP0009046_muscle_twitch0.74127137
110MP0003937_abnormal_limbs/digits/tail_de0.73428904
111MP0005408_hypopigmentation0.72159932
112MP0002233_abnormal_nose_morphology0.72148355
113MP0001188_hyperpigmentation0.71440048
114MP0008770_decreased_survivor_rate0.70747119
115MP0005377_hearing/vestibular/ear_phenot0.70610358
116MP0003878_abnormal_ear_physiology0.70610358
117MP0002127_abnormal_cardiovascular_syste0.70589023
118MP0000858_altered_metastatic_potential0.69948893
119MP0001929_abnormal_gametogenesis0.69935620
120MP0002638_abnormal_pupillary_reflex0.69622413
121MP0005367_renal/urinary_system_phenotyp0.68066548
122MP0000516_abnormal_urinary_system0.68066548
123MP0004142_abnormal_muscle_tone0.66084047
124MP0003861_abnormal_nervous_system0.65805712
125MP0006276_abnormal_autonomic_nervous0.65735201
126MP0000428_abnormal_craniofacial_morphol0.64408981
127MP0006072_abnormal_retinal_apoptosis0.63668815
128MP0000681_abnormal_thyroid_gland0.63559398
129MP0000026_abnormal_inner_ear0.63526551
130MP0005623_abnormal_meninges_morphology0.63519243
131MP0003011_delayed_dark_adaptation0.63103124
132MP0000653_abnormal_sex_gland0.62866564
133MP0002114_abnormal_axial_skeleton0.62847105
134MP0002932_abnormal_joint_morphology0.62473503
135MP0002697_abnormal_eye_size0.61291814
136MP0005384_cellular_phenotype0.61199642
137MP0002722_abnormal_immune_system0.60228676
138MP0004233_abnormal_muscle_weight0.60019513
139MP0000762_abnormal_tongue_morphology0.59704186
140MP0000749_muscle_degeneration0.57406564

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.11870448
2Reticulocytopenia (HP:0001896)5.93803552
3Abnormal number of erythroid precursors (HP:0012131)5.72601652
4Acute necrotizing encephalopathy (HP:0006965)4.53760018
5Macrocytic anemia (HP:0001972)4.22814522
6Abnormal mitochondria in muscle tissue (HP:0008316)4.19658617
7Oral leukoplakia (HP:0002745)4.00468780
8Mitochondrial inheritance (HP:0001427)3.98721145
9Increased serum pyruvate (HP:0003542)3.84395444
10Abnormality of glycolysis (HP:0004366)3.84395444
11Colon cancer (HP:0003003)3.81421161
12Pallor (HP:0000980)3.79639668
13Increased muscle lipid content (HP:0009058)3.69113064
14Birth length less than 3rd percentile (HP:0003561)3.67586344
15Increased CSF lactate (HP:0002490)3.62010983
16Hepatocellular necrosis (HP:0001404)3.59347671
17Aplastic anemia (HP:0001915)3.49605139
18Acute encephalopathy (HP:0006846)3.49294971
19Progressive macrocephaly (HP:0004481)3.46231035
20Decreased activity of mitochondrial respiratory chain (HP:0008972)3.38071759
21Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.38071759
22Type I transferrin isoform profile (HP:0003642)3.34244971
23Selective tooth agenesis (HP:0001592)3.22980478
24Exercise intolerance (HP:0003546)3.12669372
25Breast hypoplasia (HP:0003187)3.07865815
26Increased hepatocellular lipid droplets (HP:0006565)3.04126685
27Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.03030520
28Abnormal number of incisors (HP:0011064)3.02684502
29Increased serum lactate (HP:0002151)3.02246473
30Testicular atrophy (HP:0000029)2.96418257
31Aplasia/Hypoplasia of the sacrum (HP:0008517)2.95001590
32Hepatic necrosis (HP:0002605)2.93333342
33Rough bone trabeculation (HP:0100670)2.92218094
34Carpal bone hypoplasia (HP:0001498)2.89518681
35Cerebral hypomyelination (HP:0006808)2.84386434
36Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.78767900
37Patellar aplasia (HP:0006443)2.73564292
38Abnormal protein glycosylation (HP:0012346)2.71059020
39Abnormal glycosylation (HP:0012345)2.71059020
40Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.71059020
41Abnormal protein N-linked glycosylation (HP:0012347)2.71059020
42Absent thumb (HP:0009777)2.66444664
43Premature graying of hair (HP:0002216)2.63398734
44Lipid accumulation in hepatocytes (HP:0006561)2.62841581
45Trismus (HP:0000211)2.62825716
46Multiple enchondromatosis (HP:0005701)2.58254278
47Aplasia/Hypoplasia of the patella (HP:0006498)2.56019845
48Abnormal gallbladder physiology (HP:0012438)2.52274745
49Cholecystitis (HP:0001082)2.52274745
50Cellular immunodeficiency (HP:0005374)2.51266311
5111 pairs of ribs (HP:0000878)2.50380711
52Supernumerary spleens (HP:0009799)2.50031539
53Respiratory failure (HP:0002878)2.45462934
54Ragged-red muscle fibers (HP:0003200)2.42962705
55Lethargy (HP:0001254)2.42533236
56Medulloblastoma (HP:0002885)2.42347212
57Abnormality of abdominal situs (HP:0011620)2.40807805
58Abdominal situs inversus (HP:0003363)2.40807805
59Abnormality of reticulocytes (HP:0004312)2.39211261
60Microretrognathia (HP:0000308)2.38064187
61Exertional dyspnea (HP:0002875)2.36169133
62Abnormality of the anterior horn cell (HP:0006802)2.35269269
63Degeneration of anterior horn cells (HP:0002398)2.35269269
64Cerebral edema (HP:0002181)2.34352471
65Progressive muscle weakness (HP:0003323)2.33825215
66Abnormal lung lobation (HP:0002101)2.33682598
67Hyperglycinemia (HP:0002154)2.33259786
68Absent radius (HP:0003974)2.30405345
693-Methylglutaconic aciduria (HP:0003535)2.30249985
70Meckel diverticulum (HP:0002245)2.29879271
71Dicarboxylic aciduria (HP:0003215)2.27795498
72Abnormality of dicarboxylic acid metabolism (HP:0010995)2.27795498
73Horseshoe kidney (HP:0000085)2.27708519
74Lactic acidosis (HP:0003128)2.27119151
75Leukodystrophy (HP:0002415)2.26893827
76Opisthotonus (HP:0002179)2.24566011
77Asplenia (HP:0001746)2.24563206
78Abnormality of the ileum (HP:0001549)2.22263890
79Cleft eyelid (HP:0000625)2.21254485
80Reduced antithrombin III activity (HP:0001976)2.21137790
81Triphalangeal thumb (HP:0001199)2.20931939
82Emotional lability (HP:0000712)2.20008933
83Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.17183713
84Absent forearm bone (HP:0003953)2.16291174
85Aplasia involving forearm bones (HP:0009822)2.16291174
86Ependymoma (HP:0002888)2.14405493
87Microvesicular hepatic steatosis (HP:0001414)2.13098716
88Neoplasm of the pancreas (HP:0002894)2.12833758
89Abnormal trabecular bone morphology (HP:0100671)2.12755952
90Increased intramyocellular lipid droplets (HP:0012240)2.10985272
91Chromsome breakage (HP:0040012)2.10535792
92Aplasia/Hypoplasia of the spleen (HP:0010451)2.08618695
93Abnormality of the preputium (HP:0100587)2.07186500
94Tracheoesophageal fistula (HP:0002575)2.05880562
95Missing ribs (HP:0000921)2.03291693
96Chromosomal breakage induced by crosslinking agents (HP:0003221)2.01376894
97Renal Fanconi syndrome (HP:0001994)2.01285250
98Progressive microcephaly (HP:0000253)1.98205077
99Methylmalonic aciduria (HP:0012120)1.96573674
100Optic disc pallor (HP:0000543)1.96347624
101Generalized aminoaciduria (HP:0002909)1.94721578
102Broad distal phalanx of finger (HP:0009836)1.93840351
103Glossoptosis (HP:0000162)1.93531789
104Respiratory difficulties (HP:0002880)1.93484407
105Facial cleft (HP:0002006)1.90585960
106Pancytopenia (HP:0001876)1.88439271
107Myokymia (HP:0002411)1.88316631
108Severe visual impairment (HP:0001141)1.87765484
109Agnosia (HP:0010524)1.86307931
110Atresia of the external auditory canal (HP:0000413)1.86298344
111Angiofibromas (HP:0010615)1.86240037
112Adenoma sebaceum (HP:0009720)1.86240037
113Abnormality of renal resorption (HP:0011038)1.84611527
114Premature ovarian failure (HP:0008209)1.83706038
115X-linked dominant inheritance (HP:0001423)1.80120998
116Depressed nasal ridge (HP:0000457)1.79157922
117Hypoplasia of the radius (HP:0002984)1.78784773
118Sclerocornea (HP:0000647)1.78417351
119Secondary amenorrhea (HP:0000869)1.77918011
120Sparse eyelashes (HP:0000653)1.76890942
121Abnormality of the labia minora (HP:0012880)1.76099130
122Progressive external ophthalmoplegia (HP:0000590)1.74957295
123Cerebral palsy (HP:0100021)1.74858726
124Gout (HP:0001997)1.73985717
125Partial duplication of thumb phalanx (HP:0009944)1.72904437
126CNS demyelination (HP:0007305)1.72651766
127Aplasia/Hypoplasia of the uvula (HP:0010293)1.71699295
128Aplasia/hypoplasia of the uterus (HP:0008684)1.71319455
129Death in infancy (HP:0001522)1.71165432
130Gliosis (HP:0002171)1.70308876
131Truncus arteriosus (HP:0001660)1.67976465
132Hypokinesia (HP:0002375)1.63771717
133Blindness (HP:0000618)1.61873649
134Glycosuria (HP:0003076)1.61285526
135Abnormality of urine glucose concentration (HP:0011016)1.61285526
136Hyperthyroidism (HP:0000836)1.60520347
137Hyperphosphaturia (HP:0003109)1.59156651
138Vomiting (HP:0002013)1.54820663
139Muscle fiber atrophy (HP:0100295)1.51675264
140Hypoplasia of the uterus (HP:0000013)1.50719893
141Retinal dysplasia (HP:0007973)1.44652785
142Hypoplasia of the capital femoral epiphysis (HP:0003090)1.44445654

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK26.05864610
2BUB14.89020025
3WEE14.34634961
4CDC73.34323630
5NME23.15934466
6SRPK12.77187743
7TESK22.73101110
8STK162.66440685
9VRK12.66360949
10EIF2AK12.59907306
11TSSK62.47948150
12PLK42.25658738
13TLK12.03149636
14NEK11.84221192
15NME11.84162643
16CDK71.79855308
17TESK11.75930799
18MKNK11.68393205
19PLK11.67501945
20EIF2AK31.65211708
21LIMK11.60393394
22TTK1.59492047
23RPS6KB21.57561102
24PIM21.56520113
25CDK191.52911669
26AURKA1.52724459
27SCYL21.48651212
28KDR1.45813452
29CSNK1G31.44997652
30AURKB1.43950865
31NEK21.43884622
32SMG11.42351726
33PAK41.42320274
34PASK1.38987548
35MAP3K101.38890829
36BRSK21.34473890
37ATR1.31582177
38DYRK31.31046691
39MAP3K111.30640320
40PNCK1.29741687
41LRRK21.26932330
42PLK31.25795593
43NUAK11.22627869
44MAP2K71.19588842
45MAP3K81.18816707
46MAP4K21.17574718
47TAF11.17133589
48ACVR1B1.16753479
49CSNK1A1L1.16205313
50OBSCN1.16063389
51BRAF1.07586259
52ILK1.07114862
53BRSK11.06791514
54RPS6KA41.00712183
55CSNK1G10.99774928
56CSNK1G20.99203868
57DYRK20.97441819
58CHEK20.97439465
59TGFBR10.97284807
60MYLK0.95612241
61LATS20.95292119
62PAK10.95272673
63CHEK10.91857789
64PBK0.90687812
65CSNK2A20.89443542
66ZAK0.89270091
67MKNK20.89164948
68CSNK2A10.86097956
69CDK40.84399283
70PKN20.81592465
71ABL20.79798171
72FLT30.74497208
73CDK80.71879799
74STK40.71674072
75BCKDK0.69916563
76AKT20.69570251
77CCNB10.67937897
78DAPK30.67554609
79CDK20.66646057
80UHMK10.66569573
81PDK20.64844275
82IRAK30.64737077
83DAPK10.63838980
84ARAF0.63331946
85EPHA20.60123064
86ATM0.56448719
87EIF2AK20.53483761
88STK100.52758750
89EEF2K0.52574788
90PRKCI0.49941306
91CDK11A0.49537753
92GRK60.48359118
93CDK10.47502631
94PIM10.47359910
95CAMK2G0.46519233
96RPS6KA50.45435058
97STK38L0.45384009
98MAPKAPK30.45317120
99YES10.45121433
100FGFR10.43845250
101MAPKAPK50.42447680
102CDK180.40588214
103CDK150.40575202
104GRK50.39934387
105CSNK1E0.39934144
106CDK140.39096998
107BRD40.36947914
108MAP3K120.36155268
109MST40.35604216
110MUSK0.34330841
111TRIM280.33690043
112ERN10.32990541
113TAOK20.32746043
114CDK90.30878703
115BTK0.29320011
116MAP2K30.28990326
117CSNK1A10.27169187
118PRKDC0.23424533
119CAMK2D0.22991055
120RAF10.21030297
121EPHB20.20666057
122CDK120.20018327
123PRKD30.18231813
124CAMK2B0.16522155
125MINK10.15808729
126WNK30.12820660

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.44825902
2DNA replication_Homo sapiens_hsa030304.56598356
3Proteasome_Homo sapiens_hsa030503.98171606
4Mismatch repair_Homo sapiens_hsa034303.93345192
5RNA polymerase_Homo sapiens_hsa030203.69711510
6Spliceosome_Homo sapiens_hsa030403.39365545
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.06187357
8Oxidative phosphorylation_Homo sapiens_hsa001902.87625883
9Pyrimidine metabolism_Homo sapiens_hsa002402.78079463
10Parkinsons disease_Homo sapiens_hsa050122.75413381
11Base excision repair_Homo sapiens_hsa034102.69716077
12Homologous recombination_Homo sapiens_hsa034402.69459863
13Nucleotide excision repair_Homo sapiens_hsa034202.59633010
14RNA transport_Homo sapiens_hsa030132.56537474
15One carbon pool by folate_Homo sapiens_hsa006702.44189821
16Huntingtons disease_Homo sapiens_hsa050162.20635506
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.13271565
18RNA degradation_Homo sapiens_hsa030181.86128973
19Cell cycle_Homo sapiens_hsa041101.85431955
20Fatty acid elongation_Homo sapiens_hsa000621.82700496
21Alzheimers disease_Homo sapiens_hsa050101.73157273
22Fanconi anemia pathway_Homo sapiens_hsa034601.61063699
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.50642434
24Purine metabolism_Homo sapiens_hsa002301.39705598
25Non-homologous end-joining_Homo sapiens_hsa034501.37884825
26Biosynthesis of amino acids_Homo sapiens_hsa012301.35347048
27Cardiac muscle contraction_Homo sapiens_hsa042601.29810475
28Basal transcription factors_Homo sapiens_hsa030221.29193419
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.28265837
30Protein export_Homo sapiens_hsa030601.23824842
31mRNA surveillance pathway_Homo sapiens_hsa030151.23271857
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.11204039
33Cyanoamino acid metabolism_Homo sapiens_hsa004601.00562297
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.99449587
35p53 signaling pathway_Homo sapiens_hsa041150.99007921
36Carbon metabolism_Homo sapiens_hsa012000.93251537
37Systemic lupus erythematosus_Homo sapiens_hsa053220.91495471
38Epstein-Barr virus infection_Homo sapiens_hsa051690.91126200
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.90309618
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87024365
41Pentose phosphate pathway_Homo sapiens_hsa000300.86932855
42Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.84868085
43Glutathione metabolism_Homo sapiens_hsa004800.80609972
442-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80503891
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.79735125
46Vitamin B6 metabolism_Homo sapiens_hsa007500.75310654
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75180787
48Peroxisome_Homo sapiens_hsa041460.70179280
49Folate biosynthesis_Homo sapiens_hsa007900.63865138
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.62961196
51Sulfur metabolism_Homo sapiens_hsa009200.62927445
52Sulfur relay system_Homo sapiens_hsa041220.62495799
53Oocyte meiosis_Homo sapiens_hsa041140.61699771
54Fructose and mannose metabolism_Homo sapiens_hsa000510.61289693
55Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.60132620
56Propanoate metabolism_Homo sapiens_hsa006400.59187588
57Basal cell carcinoma_Homo sapiens_hsa052170.57217947
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.55137954
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.54049310
60Galactose metabolism_Homo sapiens_hsa000520.51383674
61Steroid biosynthesis_Homo sapiens_hsa001000.51176295
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50946384
63Metabolic pathways_Homo sapiens_hsa011000.50343234
64Central carbon metabolism in cancer_Homo sapiens_hsa052300.49119830
65Pyruvate metabolism_Homo sapiens_hsa006200.47955684
66Viral carcinogenesis_Homo sapiens_hsa052030.46787798
67HIF-1 signaling pathway_Homo sapiens_hsa040660.44895854
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42749457
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.42074407
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41944095
71HTLV-I infection_Homo sapiens_hsa051660.40903708
72Alcoholism_Homo sapiens_hsa050340.40265154
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39884366
74Fatty acid metabolism_Homo sapiens_hsa012120.38598602
75Thyroid cancer_Homo sapiens_hsa052160.38472825
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.37657639
77Butanoate metabolism_Homo sapiens_hsa006500.35771698
78Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35603565
79N-Glycan biosynthesis_Homo sapiens_hsa005100.35525354
80Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.33562001
81Collecting duct acid secretion_Homo sapiens_hsa049660.33228105
82Herpes simplex infection_Homo sapiens_hsa051680.32536730
83Hedgehog signaling pathway_Homo sapiens_hsa043400.30789529
84Antigen processing and presentation_Homo sapiens_hsa046120.29555667
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29473941
86Hippo signaling pathway_Homo sapiens_hsa043900.29336813
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29056969
88Primary immunodeficiency_Homo sapiens_hsa053400.27924914
89Legionellosis_Homo sapiens_hsa051340.25590478
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.25406714
91Arginine and proline metabolism_Homo sapiens_hsa003300.24535177
92Bladder cancer_Homo sapiens_hsa052190.24380142
93TGF-beta signaling pathway_Homo sapiens_hsa043500.22714979
94Selenocompound metabolism_Homo sapiens_hsa004500.20082683
95* Tyrosine metabolism_Homo sapiens_hsa003500.19903764
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.16871699
97Synaptic vesicle cycle_Homo sapiens_hsa047210.15007026
98MicroRNAs in cancer_Homo sapiens_hsa052060.14432596
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.14060692
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.12769719
101Chemical carcinogenesis_Homo sapiens_hsa052040.12198503
102beta-Alanine metabolism_Homo sapiens_hsa004100.11166273
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.10079055
104Tryptophan metabolism_Homo sapiens_hsa003800.10042004
105Arachidonic acid metabolism_Homo sapiens_hsa005900.10014076
106Fatty acid degradation_Homo sapiens_hsa000710.09726760
107Pathways in cancer_Homo sapiens_hsa052000.09717010
108Primary bile acid biosynthesis_Homo sapiens_hsa001200.08928216
109Phototransduction_Homo sapiens_hsa047440.07211186
110Wnt signaling pathway_Homo sapiens_hsa043100.06510808
111Steroid hormone biosynthesis_Homo sapiens_hsa001400.06444694
112Shigellosis_Homo sapiens_hsa051310.06019725
113Arginine biosynthesis_Homo sapiens_hsa002200.05606482
114Small cell lung cancer_Homo sapiens_hsa052220.04656981
115Colorectal cancer_Homo sapiens_hsa052100.04465642
116Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.04449519
117Notch signaling pathway_Homo sapiens_hsa043300.04178687
118Vitamin digestion and absorption_Homo sapiens_hsa049770.04079402
119Vibrio cholerae infection_Homo sapiens_hsa051100.03344215
120Apoptosis_Homo sapiens_hsa042100.02652058
121Melanoma_Homo sapiens_hsa052180.02269875
122Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.00707249
123Tight junction_Homo sapiens_hsa045300.00533843
124PI3K-Akt signaling pathway_Homo sapiens_hsa04151-0.0696240
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250-0.0679518
126Linoleic acid metabolism_Homo sapiens_hsa00591-0.0559586
127Transcriptional misregulation in cancer_Homo sapiens_hsa05202-0.0292120
128Renin-angiotensin system_Homo sapiens_hsa04614-0.0273231
129Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760-0.0018727

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