MFAP1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to cilium (GO:0061512)6.38204888
2retinal cone cell development (GO:0046549)6.09259294
3negative regulation of oligodendrocyte differentiation (GO:0048715)5.34976263
4atrial cardiac muscle cell action potential (GO:0086014)5.32310697
5response to nitrosative stress (GO:0051409)5.32299908
6cGMP-mediated signaling (GO:0019934)5.11744156
7negative regulation of inclusion body assembly (GO:0090084)5.07581863
8behavioral response to nicotine (GO:0035095)4.84815703
9presynaptic membrane assembly (GO:0097105)4.73625684
10microtubule severing (GO:0051013)4.54853617
11righting reflex (GO:0060013)4.25725125
12neuron cell-cell adhesion (GO:0007158)4.25509115
13limb bud formation (GO:0060174)4.23347042
14postsynaptic membrane organization (GO:0001941)4.19959623
15reflex (GO:0060004)4.05127389
16presynaptic membrane organization (GO:0097090)4.02915044
17otic vesicle formation (GO:0030916)4.01773845
18prepulse inhibition (GO:0060134)3.98038312
19pyrimidine nucleobase catabolic process (GO:0006208)3.92674461
20nonmotile primary cilium assembly (GO:0035058)3.88721756
21relaxation of smooth muscle (GO:0044557)3.72349730
22cardiac right ventricle morphogenesis (GO:0003215)3.67722422
23behavioral response to ethanol (GO:0048149)3.65352625
24detection of light stimulus involved in visual perception (GO:0050908)3.60229901
25detection of light stimulus involved in sensory perception (GO:0050962)3.60229901
26prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060523.58710079
27protein refolding (GO:0042026)3.58300446
28negative regulation of mast cell activation (GO:0033004)3.55042413
29retinal ganglion cell axon guidance (GO:0031290)3.45787552
30regulation of action potential (GO:0098900)3.44967891
31regulation of inclusion body assembly (GO:0090083)3.43827253
32transcription from mitochondrial promoter (GO:0006390)3.43814351
33regulation of dopamine secretion (GO:0014059)3.37450553
34water-soluble vitamin biosynthetic process (GO:0042364)3.34840122
35membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.32725147
36cAMP catabolic process (GO:0006198)3.31813960
37L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.19616881
38photoreceptor cell differentiation (GO:0046530)3.10636523
39eye photoreceptor cell differentiation (GO:0001754)3.10636523
40behavioral response to cocaine (GO:0048148)3.06846229
41thalamus development (GO:0021794)3.05247144
42artery development (GO:0060840)3.04664804
43regulation of respiratory system process (GO:0044065)3.01211233
44axon ensheathment in central nervous system (GO:0032291)2.98721407
45central nervous system myelination (GO:0022010)2.98721407
46cyclic nucleotide catabolic process (GO:0009214)2.97861464
47response to histamine (GO:0034776)2.97388747
48Sertoli cell development (GO:0060009)2.97153797
49adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.95823179
50calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.94137253
51nucleobase catabolic process (GO:0046113)2.92818125
52DNA deamination (GO:0045006)2.91344129
53mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.90975188
54photoreceptor cell development (GO:0042461)2.86227546
55gamma-aminobutyric acid transport (GO:0015812)2.84769505
56regulation of short-term neuronal synaptic plasticity (GO:0048172)2.84582351
57negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.84208548
58regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.82591473
59regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.82418257
60regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.82418257
61dendritic spine morphogenesis (GO:0060997)2.81963099
62protein-cofactor linkage (GO:0018065)2.81794318
63sensory perception of smell (GO:0007608)2.74437898
64neuron recognition (GO:0008038)2.72739264
65auditory receptor cell stereocilium organization (GO:0060088)2.71683761
66vocalization behavior (GO:0071625)2.71663787
67regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.70919477
68negative regulation of DNA-dependent DNA replication (GO:2000104)2.69843108
69short-term memory (GO:0007614)2.69499284
70negative regulation of glial cell differentiation (GO:0045686)2.68381496
71transmission of nerve impulse (GO:0019226)2.68338885
72eye photoreceptor cell development (GO:0042462)2.68309278
73mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.67382577
74radial glial cell differentiation (GO:0060019)2.66295762
75mRNA splice site selection (GO:0006376)2.66100767
76negative regulation of sodium ion transport (GO:0010766)2.65733966
77nephron epithelium morphogenesis (GO:0072088)2.65558361
78nephron tubule morphogenesis (GO:0072078)2.65558361
79neuronal stem cell maintenance (GO:0097150)2.65440568
80regulation of oligodendrocyte differentiation (GO:0048713)2.63404549
81regulation of neurotransmitter uptake (GO:0051580)2.62639704
82positive regulation of RNA splicing (GO:0033120)2.62547229
83gamma-aminobutyric acid signaling pathway (GO:0007214)2.61911459
84glycerophospholipid catabolic process (GO:0046475)2.60888675
85synapse assembly (GO:0007416)2.59604031
86kidney morphogenesis (GO:0060993)2.58606277
87regulation of synaptic transmission, dopaminergic (GO:0032225)2.56469337
88regulation of penile erection (GO:0060405)2.56003724
89negative regulation of androgen receptor signaling pathway (GO:0060766)2.55763411
90amino acid salvage (GO:0043102)2.55605920
91L-methionine salvage (GO:0071267)2.55605920
92L-methionine biosynthetic process (GO:0071265)2.55605920
93cilium morphogenesis (GO:0060271)2.55202580
94cerebral cortex radially oriented cell migration (GO:0021799)2.54775640
95mitochondrial respiratory chain complex I assembly (GO:0032981)2.54041389
96NADH dehydrogenase complex assembly (GO:0010257)2.54041389
97mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.54041389
98synaptic vesicle docking involved in exocytosis (GO:0016081)2.52931488
99positive regulation of dendritic spine development (GO:0060999)2.52262134
100adult feeding behavior (GO:0008343)2.52113540

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.71119743
2GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.67084069
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.44467051
4TAF15_26573619_Chip-Seq_HEK293_Human3.27026999
5GBX2_23144817_ChIP-Seq_PC3_Human2.71300918
6RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.46583485
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44505860
8EZH2_22144423_ChIP-Seq_EOC_Human2.43265148
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.42614019
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.42107565
11IGF1R_20145208_ChIP-Seq_DFB_Human2.34329849
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.33342827
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.23886600
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.20037607
15REST_21632747_ChIP-Seq_MESCs_Mouse2.19419673
16FUS_26573619_Chip-Seq_HEK293_Human2.14372909
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.09647761
18JARID2_20064375_ChIP-Seq_MESCs_Mouse2.06565570
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04433662
20RNF2_27304074_Chip-Seq_NSC_Mouse2.04359237
21CTBP2_25329375_ChIP-Seq_LNCAP_Human2.03229429
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.02622784
23RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.01104955
24SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.98309991
25SUZ12_27294783_Chip-Seq_ESCs_Mouse1.96240153
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.93336136
27RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.92195170
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.91319492
29ER_23166858_ChIP-Seq_MCF-7_Human1.88635687
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.86697817
31SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.80894456
32P300_19829295_ChIP-Seq_ESCs_Human1.79378398
33SMAD3_21741376_ChIP-Seq_EPCs_Human1.77233660
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.77192663
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.73745608
36EZH2_27294783_Chip-Seq_ESCs_Mouse1.71349823
37CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.71262935
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.70313848
39SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.68765628
40TOP2B_26459242_ChIP-Seq_MCF-7_Human1.68360471
41POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.68229157
42TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68229157
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.64759664
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.64399332
45SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.60463620
46UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.59427441
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56458907
48EZH2_18974828_ChIP-Seq_MESCs_Mouse1.53904254
49RNF2_18974828_ChIP-Seq_MESCs_Mouse1.53904254
50AR_21572438_ChIP-Seq_LNCaP_Human1.53706995
51SMAD4_21799915_ChIP-Seq_A2780_Human1.51496712
52NR3C1_21868756_ChIP-Seq_MCF10A_Human1.50766348
53BCAT_22108803_ChIP-Seq_LS180_Human1.49955566
54MTF2_20144788_ChIP-Seq_MESCs_Mouse1.48534367
55SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47943313
56SALL1_21062744_ChIP-ChIP_HESCs_Human1.46713197
57POU5F1_16153702_ChIP-ChIP_HESCs_Human1.45752101
58MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45651801
59EWS_26573619_Chip-Seq_HEK293_Human1.44580623
60STAT3_23295773_ChIP-Seq_U87_Human1.40590838
61AR_25329375_ChIP-Seq_VCAP_Human1.36880027
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.34022236
63CBP_20019798_ChIP-Seq_JUKART_Human1.34022236
64REST_18959480_ChIP-ChIP_MESCs_Mouse1.33432182
65GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.30849149
66VDR_22108803_ChIP-Seq_LS180_Human1.27634076
67TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26668385
68RNF2_27304074_Chip-Seq_ESCs_Mouse1.25025644
69STAT3_18555785_ChIP-Seq_MESCs_Mouse1.25004772
70RUNX2_22187159_ChIP-Seq_PCA_Human1.20701626
71TAL1_26923725_Chip-Seq_HPCs_Mouse1.20189750
72SMAD3_21741376_ChIP-Seq_ESCs_Human1.19962465
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18827283
74RING1B_27294783_Chip-Seq_NPCs_Mouse1.17945322
75SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15593515
76TCF4_22108803_ChIP-Seq_LS180_Human1.15252029
77TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14443320
78SOX9_26525672_Chip-Seq_HEART_Mouse1.12768744
79RING1B_27294783_Chip-Seq_ESCs_Mouse1.11599020
80FOXA1_21572438_ChIP-Seq_LNCaP_Human1.11121541
81TCF4_23295773_ChIP-Seq_U87_Human1.10858361
82TBX3_20139965_ChIP-Seq_ESCs_Mouse1.10613432
83RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.10164583
84OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09689187
85TBX3_20139965_ChIP-Seq_MESCs_Mouse1.09616975
86BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.08923693
87AR_19668381_ChIP-Seq_PC3_Human1.05904629
88FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.01694674
89TP63_19390658_ChIP-ChIP_HaCaT_Human1.01653980
90WDR5_24793694_ChIP-Seq_LNCAP_Human1.01034447
91PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00984052
92ERG_21242973_ChIP-ChIP_JURKAT_Human1.00326742
93ZNF274_21170338_ChIP-Seq_K562_Hela1.00278335
94SMAD4_21741376_ChIP-Seq_EPCs_Human0.98973611
95TP53_18474530_ChIP-ChIP_U2OS_Human0.98361245
96AHR_22903824_ChIP-Seq_MCF-7_Human0.97407813
97NOTCH1_21737748_ChIP-Seq_TLL_Human0.97397521
98RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95637570
99DROSHA_22980978_ChIP-Seq_HELA_Human0.95306129
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.94784576

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.84769784
2MP0001984_abnormal_olfaction3.34038392
3MP0004133_heterotaxia3.12104957
4MP0002822_catalepsy3.03094871
5MP0006292_abnormal_olfactory_placode2.94473695
6MP0005451_abnormal_body_composition2.68638199
7MP0004742_abnormal_vestibular_system2.66893323
8MP0003136_yellow_coat_color2.66690054
9MP0002734_abnormal_mechanical_nocicepti2.38804805
10MP0005171_absent_coat_pigmentation2.35352386
11MP0003787_abnormal_imprinting2.29335926
12MP0005423_abnormal_somatic_nervous2.23292269
13MP0006276_abnormal_autonomic_nervous2.19964529
14MP0000778_abnormal_nervous_system2.12272730
15MP0003121_genomic_imprinting2.08444883
16MP0004270_analgesia2.04067690
17MP0001486_abnormal_startle_reflex1.94535939
18MP0008877_abnormal_DNA_methylation1.89478230
19MP0006072_abnormal_retinal_apoptosis1.88007252
20MP0004859_abnormal_synaptic_plasticity1.85264313
21MP0002928_abnormal_bile_duct1.82813013
22MP0005551_abnormal_eye_electrophysiolog1.82506663
23MP0009745_abnormal_behavioral_response1.80400693
24MP0001440_abnormal_grooming_behavior1.78948106
25MP0003122_maternal_imprinting1.75901839
26MP0002572_abnormal_emotion/affect_behav1.73786758
27MP0003011_delayed_dark_adaptation1.72126049
28MP0003635_abnormal_synaptic_transmissio1.71885080
29MP0002063_abnormal_learning/memory/cond1.70532306
30MP0002736_abnormal_nociception_after1.69019129
31MP0002064_seizures1.66858783
32MP0002272_abnormal_nervous_system1.66521969
33MP0004885_abnormal_endolymph1.65232481
34MP0001485_abnormal_pinna_reflex1.57256582
35MP0001968_abnormal_touch/_nociception1.53496454
36MP0003283_abnormal_digestive_organ1.51163205
37MP0005253_abnormal_eye_physiology1.50389542
38MP0001177_atelectasis1.47681200
39MP0001970_abnormal_pain_threshold1.46492322
40MP0008872_abnormal_physiological_respon1.44526426
41MP0002249_abnormal_larynx_morphology1.40381769
42MP0003938_abnormal_ear_development1.38587099
43MP0000955_abnormal_spinal_cord1.38457000
44MP0000049_abnormal_middle_ear1.37485432
45MP0000631_abnormal_neuroendocrine_gland1.36783588
46MP0002557_abnormal_social/conspecific_i1.28491954
47MP0002752_abnormal_somatic_nervous1.20176335
48MP0005646_abnormal_pituitary_gland1.19248126
49MP0002735_abnormal_chemical_nociception1.17797763
50MP0004142_abnormal_muscle_tone1.17522099
51MP0001529_abnormal_vocalization1.15692817
52MP0002067_abnormal_sensory_capabilities1.12110862
53MP0003123_paternal_imprinting1.10948143
54MP0001502_abnormal_circadian_rhythm1.10544125
55MP0006035_abnormal_mitochondrial_morpho1.06436310
56MP0002282_abnormal_trachea_morphology1.05834033
57MP0002697_abnormal_eye_size1.04723755
58MP0003137_abnormal_impulse_conducting1.04570388
59MP0000026_abnormal_inner_ear1.02013311
60MP0004084_abnormal_cardiac_muscle1.01753200
61MP0005195_abnormal_posterior_eye1.01300266
62MP0002638_abnormal_pupillary_reflex0.98494140
63MP0002108_abnormal_muscle_morphology0.97961562
64MP0005503_abnormal_tendon_morphology0.97851079
65MP0002882_abnormal_neuron_morphology0.97013250
66MP0001905_abnormal_dopamine_level0.95771221
67MP0002184_abnormal_innervation0.95436839
68MP0009278_abnormal_bone_marrow0.94562058
69MP0003861_abnormal_nervous_system0.93285868
70MP0001963_abnormal_hearing_physiology0.91317873
71MP0003690_abnormal_glial_cell0.91247688
72MP0002152_abnormal_brain_morphology0.90763354
73MP0004811_abnormal_neuron_physiology0.89383762
74MP0001919_abnormal_reproductive_system0.88997560
75MP0009379_abnormal_foot_pigmentation0.87882986
76MP0004134_abnormal_chest_morphology0.86276800
77MP0001324_abnormal_eye_pigmentation0.85814475
78MP0005391_vision/eye_phenotype0.84685307
79MP0005084_abnormal_gallbladder_morpholo0.84435499
80MP0001501_abnormal_sleep_pattern0.84072753
81MP0009046_muscle_twitch0.83968925
82MP0004043_abnormal_pH_regulation0.83172131
83MP0004215_abnormal_myocardial_fiber0.82919128
84MP0002066_abnormal_motor_capabilities/c0.82539698
85MP0000579_abnormal_nail_morphology0.82433764
86MP0002938_white_spotting0.82414127
87MP0003221_abnormal_cardiomyocyte_apopto0.82010290
88MP0000534_abnormal_ureter_morphology0.81528507
89MP0005187_abnormal_penis_morphology0.80660006
90MP0005367_renal/urinary_system_phenotyp0.79327686
91MP0000516_abnormal_urinary_system0.79327686
92MP0005620_abnormal_muscle_contractility0.78994999
93MP0005389_reproductive_system_phenotype0.78818854
94MP0003890_abnormal_embryonic-extraembry0.78086908
95MP0002233_abnormal_nose_morphology0.74515657
96MP0003943_abnormal_hepatobiliary_system0.73758509
97MP0002332_abnormal_exercise_endurance0.73683009
98MP0001188_hyperpigmentation0.71528951
99MP0000647_abnormal_sebaceous_gland0.68386556
100MP0008569_lethality_at_weaning0.67291694

Predicted human phenotypes

RankGene SetZ-score
1Genetic anticipation (HP:0003743)4.29042585
2Metaphyseal dysplasia (HP:0100255)3.96179579
3Exercise-induced muscle cramps (HP:0003710)3.73243361
4Congenital sensorineural hearing impairment (HP:0008527)3.72471302
5Abnormality of the labia minora (HP:0012880)3.34209211
6IgM deficiency (HP:0002850)3.15085231
7Tracheomalacia (HP:0002779)3.02919845
8Abnormality of the ischium (HP:0003174)2.97742536
9True hermaphroditism (HP:0010459)2.94716937
10Nephronophthisis (HP:0000090)2.90585879
11Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.89685842
12Degeneration of the lateral corticospinal tracts (HP:0002314)2.89685842
13Bronchomalacia (HP:0002780)2.82704846
14Aplasia/Hypoplasia of the tibia (HP:0005772)2.81509919
15Birth length less than 3rd percentile (HP:0003561)2.80025808
16Oligodactyly (HP:0012165)2.80017247
17Medial flaring of the eyebrow (HP:0010747)2.77709455
18Labial hypoplasia (HP:0000066)2.76517692
19Genital tract atresia (HP:0001827)2.60322804
20Hypoplastic female external genitalia (HP:0012815)2.59824867
21Pancreatic fibrosis (HP:0100732)2.59148221
22Hypoplastic labia majora (HP:0000059)2.58372386
23Nephrogenic diabetes insipidus (HP:0009806)2.57191800
24Gait imbalance (HP:0002141)2.56659833
25Oligodactyly (hands) (HP:0001180)2.52759615
26Molar tooth sign on MRI (HP:0002419)2.50923394
27Abnormality of midbrain morphology (HP:0002418)2.50923394
28Short tibia (HP:0005736)2.49915609
29Bilateral microphthalmos (HP:0007633)2.46235779
30Congenital primary aphakia (HP:0007707)2.43686423
31Azoospermia (HP:0000027)2.38766711
32Hypoglycemic seizures (HP:0002173)2.37844609
33Specific learning disability (HP:0001328)2.37464004
34Annular pancreas (HP:0001734)2.37029439
35Abnormality of the labia majora (HP:0012881)2.36516031
36Focal motor seizures (HP:0011153)2.35821985
37Fibular aplasia (HP:0002990)2.33843322
38Poor head control (HP:0002421)2.33625125
39Progressive cerebellar ataxia (HP:0002073)2.33575582
40Lissencephaly (HP:0001339)2.32535243
41Agitation (HP:0000713)2.31052222
42Bicornuate uterus (HP:0000813)2.30688924
43Abnormality of the renal medulla (HP:0100957)2.23148944
44Urinary urgency (HP:0000012)2.22153836
45Vaginal atresia (HP:0000148)2.19695531
46Abnormality of the labia (HP:0000058)2.15129057
47Ulnar claw (HP:0001178)2.15059866
48Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.14285080
49Aplasia involving bones of the extremities (HP:0009825)2.11322802
50Aplasia involving bones of the upper limbs (HP:0009823)2.11322802
51Aplasia of the phalanges of the hand (HP:0009802)2.11322802
52Concave nail (HP:0001598)2.09258990
53Abnormal number of incisors (HP:0011064)2.08177860
54Abnormality of the corticospinal tract (HP:0002492)2.07700806
55Horizontal nystagmus (HP:0000666)2.07590463
56Abnormality of the aortic arch (HP:0012303)2.06535126
57Myokymia (HP:0002411)2.02066695
58CNS hypomyelination (HP:0003429)2.00235091
59Methylmalonic aciduria (HP:0012120)1.99372362
60Aplasia/Hypoplasia of the sternum (HP:0006714)1.99156218
61Febrile seizures (HP:0002373)1.98820795
62Abnormal spermatogenesis (HP:0008669)1.98305490
63Brushfield spots (HP:0001088)1.97670411
64Large for gestational age (HP:0001520)1.96064856
65Hypoplastic ischia (HP:0003175)1.94407416
66Poor coordination (HP:0002370)1.93338772
67Aplasia/Hypoplasia of the fibula (HP:0006492)1.92481605
68Abnormality of lateral ventricle (HP:0030047)1.91894621
69Hyperinsulinemic hypoglycemia (HP:0000825)1.91743603
70Glossoptosis (HP:0000162)1.91541745
71Patellar aplasia (HP:0006443)1.91454440
72Hepatocellular necrosis (HP:0001404)1.90616256
73Scanning speech (HP:0002168)1.90280405
74Hyperventilation (HP:0002883)1.90051572
75Hypoglycemic coma (HP:0001325)1.89328151
76Patchy hypopigmentation of hair (HP:0011365)1.88731601
77Abnormality of the pubic bones (HP:0003172)1.88181122
78Aplasia/Hypoplasia of the patella (HP:0006498)1.87643326
79Hemiparesis (HP:0001269)1.86089066
80Scrotal hypoplasia (HP:0000046)1.85155424
81Heterochromia iridis (HP:0001100)1.84390619
82Esophageal atresia (HP:0002032)1.83058788
83Anophthalmia (HP:0000528)1.81783629
84Selective tooth agenesis (HP:0001592)1.80164571
85Sclerocornea (HP:0000647)1.79762025
86Peripheral hypomyelination (HP:0007182)1.79138404
87Abnormality of the phalanges of the 2nd finger (HP:0009541)1.77899424
88Impulsivity (HP:0100710)1.77639673
89Aplasia/Hypoplasia of the lens (HP:0008063)1.76991697
90Methylmalonic acidemia (HP:0002912)1.76845748
91Postaxial hand polydactyly (HP:0001162)1.76265722
92Myotonia (HP:0002486)1.74836249
93Abnormal drinking behavior (HP:0030082)1.74824631
94Polydipsia (HP:0001959)1.74824631
95Aqueductal stenosis (HP:0002410)1.74337178
96Aplasia/Hypoplasia of the spleen (HP:0010451)1.74121658
97Pancreatic cysts (HP:0001737)1.73116774
98Pancreatic islet-cell hyperplasia (HP:0004510)1.72837420
99Breast aplasia (HP:0100783)1.71410636
100Polyuria (HP:0000103)1.71374627

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK5.02527963
2MAPK154.99531214
3SIK23.52425905
4CASK3.33641079
5TSSK63.08385611
6PNCK2.98586823
7SCYL22.47747362
8MAPKAPK52.43025893
9PKN22.31143217
10FRK2.28844305
11DYRK22.17175748
12MARK12.01897332
13EPHA41.96291722
14MAPK131.88814187
15INSRR1.83552427
16PAK31.60687849
17FLT31.59252173
18NTRK21.44085343
19GRK11.35763725
20MAP3K41.31479993
21TAOK11.29082172
22DYRK1B1.28985316
23NTRK31.27123981
24DDR21.25836462
25PINK11.25713438
26SRPK11.24344282
27MINK11.23777238
28CSNK1G21.23492905
29OBSCN1.16834264
30CDK31.12349831
31OXSR11.06164972
32EPHB20.97585228
33MAP2K70.95876920
34CAMK2A0.95036884
35DYRK30.94168231
36UHMK10.93555396
37FER0.93520280
38CHUK0.92889156
39STK390.90886108
40PRKCG0.88525940
41PLK20.88404148
42PAK60.85195921
43DYRK1A0.83527159
44MARK20.83452439
45STK380.83447650
46MAP2K40.78790853
47CSNK1A1L0.78615403
48ERBB20.76714034
49PHKG10.76058559
50PHKG20.76058559
51MKNK20.74979654
52MKNK10.73566025
53PTK2B0.72581294
54PRKG10.72328796
55CSNK1G10.71329850
56CAMK2B0.68600266
57FGFR20.67909197
58PRKD20.66148186
59WEE10.65725510
60ERBB30.65180785
61PRKCE0.63871031
62WNK30.63658976
63TNK20.62316376
64NLK0.62084203
65MAP3K90.59235357
66TAOK30.59172361
67PRKACA0.58447872
68EPHA30.55934244
69BMPR1B0.53948018
70TTK0.53357334
71MATK0.53044275
72CDK50.51259631
73CSNK1G30.50553722
74MAPKAPK30.50028132
75PLK40.48596387
76MAP3K60.48393598
77ADRBK20.47340003
78PRKG20.45061856
79ROCK10.44010467
80ERBB40.43965447
81VRK10.43763849
82CSNK1E0.40227082
83MAPK80.39755510
84STK110.38752067
85KSR10.38028814
86PRKACB0.37918064
87PRKCA0.36676624
88ADRBK10.36399820
89CSNK1A10.35905506
90DAPK20.35361799
91PRKCH0.35058645
92MAP3K20.34837347
93MAPK100.33480175
94ACVR1B0.33478715
95SIK30.33050338
96ABL20.31707702
97RPS6KA30.30587526
98CAMK10.30518957
99CAMK2G0.28382321
100CSNK2A10.27689835

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.62015863
2Phototransduction_Homo sapiens_hsa047443.79433170
3Cardiac muscle contraction_Homo sapiens_hsa042602.70597833
4Morphine addiction_Homo sapiens_hsa050322.67214630
5Oxidative phosphorylation_Homo sapiens_hsa001902.64109985
6Circadian entrainment_Homo sapiens_hsa047132.54482229
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.28460112
8GABAergic synapse_Homo sapiens_hsa047272.18440941
9Parkinsons disease_Homo sapiens_hsa050121.99261268
10Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.80918440
11Glutamatergic synapse_Homo sapiens_hsa047241.79306176
12Olfactory transduction_Homo sapiens_hsa047401.74158496
13Homologous recombination_Homo sapiens_hsa034401.72890789
14Huntingtons disease_Homo sapiens_hsa050161.62841038
15Steroid biosynthesis_Homo sapiens_hsa001001.62823615
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.55444217
17Glutathione metabolism_Homo sapiens_hsa004801.53711221
18Protein export_Homo sapiens_hsa030601.52985967
19Collecting duct acid secretion_Homo sapiens_hsa049661.47273828
20Vitamin digestion and absorption_Homo sapiens_hsa049771.37634327
21Alzheimers disease_Homo sapiens_hsa050101.37488181
22Hedgehog signaling pathway_Homo sapiens_hsa043401.37241355
23Selenocompound metabolism_Homo sapiens_hsa004501.36482275
24Dilated cardiomyopathy_Homo sapiens_hsa054141.34018944
25Taste transduction_Homo sapiens_hsa047421.32721141
26Linoleic acid metabolism_Homo sapiens_hsa005911.32689257
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.29755989
28Salivary secretion_Homo sapiens_hsa049701.29533612
29Synaptic vesicle cycle_Homo sapiens_hsa047211.28106499
30Insulin secretion_Homo sapiens_hsa049111.23019158
31Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.22565615
32Oxytocin signaling pathway_Homo sapiens_hsa049211.20624139
33Long-term depression_Homo sapiens_hsa047301.19552088
34Arachidonic acid metabolism_Homo sapiens_hsa005901.19015686
35Serotonergic synapse_Homo sapiens_hsa047261.18763699
36Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.18533089
37Chemical carcinogenesis_Homo sapiens_hsa052041.18348850
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17245487
39Ovarian steroidogenesis_Homo sapiens_hsa049131.12878801
40Cholinergic synapse_Homo sapiens_hsa047251.12675941
41Dopaminergic synapse_Homo sapiens_hsa047281.11681022
42Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.10121911
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09887123
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.07845358
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07536047
46Basal cell carcinoma_Homo sapiens_hsa052171.05434321
47Calcium signaling pathway_Homo sapiens_hsa040201.03641434
48Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.03600064
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.01930634
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01595106
51Cocaine addiction_Homo sapiens_hsa050300.95858956
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.94180612
53Gastric acid secretion_Homo sapiens_hsa049710.91792565
54Circadian rhythm_Homo sapiens_hsa047100.90432581
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89199488
56RNA polymerase_Homo sapiens_hsa030200.87240758
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.86463424
58cAMP signaling pathway_Homo sapiens_hsa040240.85718436
59Axon guidance_Homo sapiens_hsa043600.81736294
60Aldosterone synthesis and secretion_Homo sapiens_hsa049250.81178105
61Vascular smooth muscle contraction_Homo sapiens_hsa042700.80710148
62Thyroid hormone synthesis_Homo sapiens_hsa049180.79904656
63Antigen processing and presentation_Homo sapiens_hsa046120.77875221
64Peroxisome_Homo sapiens_hsa041460.77243126
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75126631
66Melanogenesis_Homo sapiens_hsa049160.72621457
67Fatty acid biosynthesis_Homo sapiens_hsa000610.72380988
68Basal transcription factors_Homo sapiens_hsa030220.71470740
69Gap junction_Homo sapiens_hsa045400.70164405
70Spliceosome_Homo sapiens_hsa030400.69327543
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69154523
72Amphetamine addiction_Homo sapiens_hsa050310.67668274
73Wnt signaling pathway_Homo sapiens_hsa043100.65749664
74Estrogen signaling pathway_Homo sapiens_hsa049150.63277903
75Tryptophan metabolism_Homo sapiens_hsa003800.62521754
76Glycerolipid metabolism_Homo sapiens_hsa005610.61729953
77Retinol metabolism_Homo sapiens_hsa008300.61302850
78MAPK signaling pathway_Homo sapiens_hsa040100.57611805
79Bile secretion_Homo sapiens_hsa049760.55568299
80Pancreatic secretion_Homo sapiens_hsa049720.54465977
81Rap1 signaling pathway_Homo sapiens_hsa040150.53235232
82Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.53153450
83Fatty acid elongation_Homo sapiens_hsa000620.53056881
84Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52646476
85Renin secretion_Homo sapiens_hsa049240.51718238
86Oocyte meiosis_Homo sapiens_hsa041140.50781749
87PPAR signaling pathway_Homo sapiens_hsa033200.47977208
88Ras signaling pathway_Homo sapiens_hsa040140.47528529
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46941452
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.46185131
91Hippo signaling pathway_Homo sapiens_hsa043900.45887754
92One carbon pool by folate_Homo sapiens_hsa006700.45703160
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44837034
94Ether lipid metabolism_Homo sapiens_hsa005650.43455512
95Melanoma_Homo sapiens_hsa052180.42170510
96Butanoate metabolism_Homo sapiens_hsa006500.41793685
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40250139
98Steroid hormone biosynthesis_Homo sapiens_hsa001400.40194172
99mRNA surveillance pathway_Homo sapiens_hsa030150.39391334
100GnRH signaling pathway_Homo sapiens_hsa049120.38226243

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »