METTL7B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.57192847
2L-phenylalanine catabolic process (GO:0006559)7.57192847
3cellular response to leptin stimulus (GO:0044320)7.30709168
4L-phenylalanine metabolic process (GO:0006558)7.25429447
5erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.25429447
6fatty acid elongation (GO:0030497)6.92734750
7aromatic amino acid family catabolic process (GO:0009074)6.86560236
8regulation of cilium movement (GO:0003352)6.40073593
9indole-containing compound catabolic process (GO:0042436)6.23051131
10indolalkylamine catabolic process (GO:0046218)6.23051131
11tryptophan catabolic process (GO:0006569)6.23051131
12very long-chain fatty acid metabolic process (GO:0000038)6.10101727
13triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.04221938
14kynurenine metabolic process (GO:0070189)6.01113831
15response to leptin (GO:0044321)5.98332405
16artery smooth muscle contraction (GO:0014824)5.90808849
17bile acid biosynthetic process (GO:0006699)5.87467016
18glyoxylate metabolic process (GO:0046487)5.86123753
19tryptophan metabolic process (GO:0006568)5.85517910
20urea cycle (GO:0000050)5.55996825
21urea metabolic process (GO:0019627)5.55996825
22sulfur amino acid catabolic process (GO:0000098)5.53511176
23alpha-linolenic acid metabolic process (GO:0036109)5.51678243
24cysteine metabolic process (GO:0006534)5.48730432
25high-density lipoprotein particle remodeling (GO:0034375)5.31500415
26negative regulation of fibrinolysis (GO:0051918)5.30567702
27epoxygenase P450 pathway (GO:0019373)5.25677452
28serine family amino acid catabolic process (GO:0009071)5.17403697
29tonic smooth muscle contraction (GO:0014820)5.16957700
30complement activation, alternative pathway (GO:0006957)5.16445506
31protein carboxylation (GO:0018214)5.13202601
32peptidyl-glutamic acid carboxylation (GO:0017187)5.13202601
33nitrogen cycle metabolic process (GO:0071941)5.12593771
34regulation of fibrinolysis (GO:0051917)5.10137463
35negative regulation of response to food (GO:0032096)5.08215830
36negative regulation of appetite (GO:0032099)5.08215830
37regulation of protein activation cascade (GO:2000257)5.07573600
38alkaloid metabolic process (GO:0009820)5.04953870
39bile acid metabolic process (GO:0008206)5.04277674
40C4-dicarboxylate transport (GO:0015740)5.00815383
41aromatic amino acid family metabolic process (GO:0009072)4.99033269
42fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.95652398
43homocysteine metabolic process (GO:0050667)4.94835013
44regulation of cardiac muscle cell contraction (GO:0086004)4.86821373
45linoleic acid metabolic process (GO:0043651)4.85201640
46lysine catabolic process (GO:0006554)4.81647352
47lysine metabolic process (GO:0006553)4.81647352
48tyrosine metabolic process (GO:0006570)4.76896512
49ovulation cycle (GO:0042698)4.76199686
50regulation of complement activation (GO:0030449)4.75458765
51regulation of triglyceride catabolic process (GO:0010896)4.72010410
52cellular ketone body metabolic process (GO:0046950)4.71059011
53omega-hydroxylase P450 pathway (GO:0097267)4.69841702
54alpha-amino acid catabolic process (GO:1901606)4.65917248
55regulation of cholesterol esterification (GO:0010872)4.65873462
56amino-acid betaine metabolic process (GO:0006577)4.65357069
57drug metabolic process (GO:0017144)4.61417724
58reverse cholesterol transport (GO:0043691)4.60920920
59lipopolysaccharide biosynthetic process (GO:0009103)4.57460504
60protein-lipid complex remodeling (GO:0034368)4.56338229
61macromolecular complex remodeling (GO:0034367)4.56338229
62plasma lipoprotein particle remodeling (GO:0034369)4.56338229
63negative regulation of sterol transport (GO:0032372)4.54037920
64negative regulation of cholesterol transport (GO:0032375)4.54037920
65bile acid and bile salt transport (GO:0015721)4.50329051
66triglyceride homeostasis (GO:0070328)4.48509489
67acylglycerol homeostasis (GO:0055090)4.48509489
68nonmotile primary cilium assembly (GO:0035058)4.43928131
69indolalkylamine metabolic process (GO:0006586)4.40782882
70phospholipid efflux (GO:0033700)4.40768372
71cellular glucuronidation (GO:0052695)4.38973266
72coenzyme catabolic process (GO:0009109)4.37089919
73cellular amino acid catabolic process (GO:0009063)4.32528887
74glycine metabolic process (GO:0006544)4.32012384
75cellular biogenic amine catabolic process (GO:0042402)4.30747157
76amine catabolic process (GO:0009310)4.30747157
77signal peptide processing (GO:0006465)4.28228762
78glutamate metabolic process (GO:0006536)4.26566036
79serine family amino acid metabolic process (GO:0009069)4.23835076
80drug catabolic process (GO:0042737)4.21632429
81striatum development (GO:0021756)4.21347260
82benzene-containing compound metabolic process (GO:0042537)4.19090977
83plasma lipoprotein particle clearance (GO:0034381)4.18104464
84imidazole-containing compound metabolic process (GO:0052803)4.16919732
85regulation of vascular endothelial growth factor signaling pathway (GO:1900746)4.15317717
86negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)4.14946767
87cellular modified amino acid catabolic process (GO:0042219)4.14604210
88fat-soluble vitamin biosynthetic process (GO:0042362)4.08630447
89ethanol oxidation (GO:0006069)4.08333308
90ketone body metabolic process (GO:1902224)4.08061573
91regulation of protein glycosylation (GO:0060049)4.06818094
92neurotransmitter uptake (GO:0001504)4.03410723
93serine family amino acid biosynthetic process (GO:0009070)4.01534471
94regulation of response to food (GO:0032095)4.00625464
95cholesterol efflux (GO:0033344)4.00065278
96lipopolysaccharide metabolic process (GO:0008653)4.00060402
97dicarboxylic acid biosynthetic process (GO:0043650)3.97923324
98aldehyde catabolic process (GO:0046185)3.96489972
99arginine metabolic process (GO:0006525)3.96250621
100glucuronate metabolic process (GO:0019585)3.92876285
101uronic acid metabolic process (GO:0006063)3.92876285
102oxidative demethylation (GO:0070989)3.89081385
103short-chain fatty acid metabolic process (GO:0046459)3.86544266
104regulation of relaxation of muscle (GO:1901077)3.83653508
105fibrinolysis (GO:0042730)3.83136720
106plasma lipoprotein particle assembly (GO:0034377)3.82337685
107drug transmembrane transport (GO:0006855)3.80650758
108organic acid catabolic process (GO:0016054)3.80017834
109carboxylic acid catabolic process (GO:0046395)3.80017834
110low-density lipoprotein particle remodeling (GO:0034374)3.79206228
111regulation of bile acid biosynthetic process (GO:0070857)3.78121895
112L-amino acid import (GO:0043092)3.77763058
113acetyl-CoA metabolic process (GO:0006084)3.77333933
114brain morphogenesis (GO:0048854)3.77320176
115exogenous drug catabolic process (GO:0042738)3.76971474
116regulation of actin filament-based movement (GO:1903115)3.76217223
117cofactor catabolic process (GO:0051187)3.72188167
118regulation of cholesterol homeostasis (GO:2000188)3.70558639
119urate metabolic process (GO:0046415)3.70219184
120cholesterol homeostasis (GO:0042632)3.67937764
121flavonoid metabolic process (GO:0009812)3.67885194
122regulation of microtubule-based movement (GO:0060632)3.67356273
123phospholipid homeostasis (GO:0055091)3.67007121
124positive regulation of triglyceride lipase activity (GO:0061365)3.66642744
125positive regulation of lipoprotein lipase activity (GO:0051006)3.66642744
126sterol homeostasis (GO:0055092)3.62722131
127regulation of cholesterol biosynthetic process (GO:0045540)3.62682781
128positive regulation of lipid catabolic process (GO:0050996)3.62444092
129very-low-density lipoprotein particle assembly (GO:0034379)3.62410846
130negative regulation of lipase activity (GO:0060192)3.61782985
131blood coagulation, intrinsic pathway (GO:0007597)3.60981510
132vascular smooth muscle contraction (GO:0014829)3.60210230
133complement activation, classical pathway (GO:0006958)3.59291287
134complement activation (GO:0006956)3.56234745
135NAD biosynthetic process (GO:0009435)3.55902398
136aspartate family amino acid catabolic process (GO:0009068)3.54730535
137long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.46131139
138regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.39704529
139glutamine family amino acid biosynthetic process (GO:0009084)3.38809804
140xenobiotic catabolic process (GO:0042178)3.37721096
141fatty-acyl-CoA biosynthetic process (GO:0046949)3.30950925
142regulation of cell communication by electrical coupling (GO:0010649)3.30307732
143branched-chain amino acid catabolic process (GO:0009083)3.28942161
144hyperosmotic salinity response (GO:0042538)3.25981663
145response to misfolded protein (GO:0051788)3.17363634
146phenylpropanoid metabolic process (GO:0009698)3.16195133
147tricarboxylic acid cycle (GO:0006099)3.15141549
148respiratory tube development (GO:0030323)3.14122126
149renal absorption (GO:0070293)3.12082413
150one-carbon compound transport (GO:0019755)3.10359884
151tetrahydrofolate metabolic process (GO:0046653)3.08738997
152regulation of appetite (GO:0032098)3.00293252
153carnitine metabolic process (GO:0009437)3.00099524
154daunorubicin metabolic process (GO:0044597)2.99791194
155polyketide metabolic process (GO:0030638)2.99791194
156doxorubicin metabolic process (GO:0044598)2.99791194
157thioester biosynthetic process (GO:0035384)2.99423311
158acyl-CoA biosynthetic process (GO:0071616)2.99423311
159negative regulation of multicellular organism growth (GO:0040015)2.99106278
160regulation of cholesterol metabolic process (GO:0090181)2.97818980
161amino acid import (GO:0043090)2.94596847

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.32069482
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.14631101
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.81575330
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.41978129
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.22259431
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.98590415
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.91866977
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.97214655
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.88108388
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.29901377
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.97409662
12VDR_22108803_ChIP-Seq_LS180_Human2.35103925
13IGF1R_20145208_ChIP-Seq_DFB_Human2.22210163
14ER_23166858_ChIP-Seq_MCF-7_Human2.13928739
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.10904375
16TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.09173857
17TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05886902
18EZH2_22144423_ChIP-Seq_EOC_Human2.03404953
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.7855427
20GBX2_23144817_ChIP-Seq_PC3_Human1.75525851
21ZNF274_21170338_ChIP-Seq_K562_Hela1.66791701
22FOXA2_19822575_ChIP-Seq_HepG2_Human1.58824805
23CLOCK_20551151_ChIP-Seq_293T_Human1.58612902
24SRF_21415370_ChIP-Seq_HL-1_Mouse1.56166622
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.53621294
26NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48533687
27HTT_18923047_ChIP-ChIP_STHdh_Human1.48490724
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.46883653
29KLF5_20875108_ChIP-Seq_MESCs_Mouse1.43690794
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.42959428
31CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.42681381
32* HNF4A_19822575_ChIP-Seq_HepG2_Human1.42266732
33AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.42192291
34KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.41658882
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.38204121
36CJUN_26792858_Chip-Seq_BT549_Human1.37026146
37POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34825821
38ELK1_22589737_ChIP-Seq_MCF10A_Human1.30141039
39SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28181645
40STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.27692839
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.26544533
42GATA1_22025678_ChIP-Seq_K562_Human1.25545457
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.23278154
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.20922571
45STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.17303943
46* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.16164422
47TCF4_23295773_ChIP-Seq_U87_Human1.15745368
48CTBP2_25329375_ChIP-Seq_LNCAP_Human1.12908866
49ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10892211
50TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.10572401
51FOXH1_21741376_ChIP-Seq_EPCs_Human1.10512827
52JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.09834821
53ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.09325682
54STAT3_23295773_ChIP-Seq_U87_Human1.08668193
55SOX2_27498859_Chip-Seq_STOMACH_Mouse1.08537841
56IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.07672909
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.05577364
58AR_25329375_ChIP-Seq_VCAP_Human1.05433952
59CBP_20019798_ChIP-Seq_JUKART_Human1.04404997
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04404997
61SMAD3_21741376_ChIP-Seq_HESCs_Human1.04381066
62TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02511729
63SOX2_19829295_ChIP-Seq_ESCs_Human1.01732944
64NANOG_19829295_ChIP-Seq_ESCs_Human1.01732944
65POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99206302
66TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99206302
67HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.98669740
68ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97661281
69TCF4_22108803_ChIP-Seq_LS180_Human0.95995049
70JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95903344
71RARG_19884340_ChIP-ChIP_MEFs_Mouse0.95342142
72CTBP1_25329375_ChIP-Seq_LNCAP_Human0.95265082
73SUZ12_27294783_Chip-Seq_NPCs_Mouse0.94499439
74SMAD4_21799915_ChIP-Seq_A2780_Human0.94348125
75PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93880383
76PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.93504167
77JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93477506
78CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.92974258
79TCF4_18268006_ChIP-ChIP_LS174T_Human0.92899413
80GATA4_25053715_ChIP-Seq_YYC3_Human0.91553245
81ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.90669852
82OCT4_20526341_ChIP-Seq_ESCs_Human0.90398752
83CDX2_19796622_ChIP-Seq_MESCs_Mouse0.85133079
84FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.84815887
85CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.83109276
86EP300_21415370_ChIP-Seq_HL-1_Mouse0.82878630
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.82410709
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.82204906
89ELK1_19687146_ChIP-ChIP_HELA_Human0.82031726
90ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.81833759
91AUTS2_25519132_ChIP-Seq_293T-REX_Human0.80764664
92YY1_21170310_ChIP-Seq_MESCs_Mouse0.80279293
93SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.79752315
94IRF8_22096565_ChIP-ChIP_GC-B_Human0.79640430
95PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.79527385
96NFE2_27457419_Chip-Seq_LIVER_Mouse0.79034514
97KAP1_22055183_ChIP-Seq_ESCs_Mouse0.78576152
98STAT1_20625510_ChIP-Seq_HELA_Human0.78274287
99BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.77947389
100SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77921228
101CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.77791996
102ZFP57_27257070_Chip-Seq_ESCs_Mouse0.77759686
103SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.77257907
104ESR2_21235772_ChIP-Seq_MCF-7_Human0.75524998
105ZNF263_19887448_ChIP-Seq_K562_Human0.75109517
106RARA_24833708_ChIP-Seq_LIVER_Mouse0.74870912
107NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.73535447
108AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.71900848
109RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.70905073
110CDX2_20551321_ChIP-Seq_CACO-2_Human0.69845800
111BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.69782378
112* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.69617922
113SALL4_18804426_ChIP-ChIP_XEN_Mouse0.69225753
114* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.69031960
115NRF2_20460467_ChIP-Seq_MEFs_Mouse0.66130603
116NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.66130603
117RAD21_21589869_ChIP-Seq_MESCs_Mouse0.66118325
118RARB_24833708_ChIP-Seq_LIVER_Mouse0.63051898
119EGR1_19032775_ChIP-ChIP_M12_Human0.62886503
120NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.61768426
121LXR_22292898_ChIP-Seq_THP-1_Human0.59703145
122ESR1_21235772_ChIP-Seq_MCF-7_Human0.59613059
123CEBPB_22108803_ChIP-Seq_LS180_Human0.58534977
124PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.57539383
125MYC_19915707_ChIP-ChIP_AK7_Human0.56270238
126STAT3_1855785_ChIP-Seq_MESCs_Mouse0.56147049
127FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.55587138
128FOXA1_25552417_ChIP-Seq_VCAP_Human0.55200271
129AR_20517297_ChIP-Seq_VCAP_Human0.51756388
130GATA6_25053715_ChIP-Seq_YYC3_Human0.51195541
131ESET_19884257_ChIP-Seq_ESCs_Mouse0.50142837
132FOXO3_23340844_ChIP-Seq_DLD1_Human0.49442521
133PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.49150557
134FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.48606679
135STAT1_17558387_ChIP-Seq_HELA_Human0.47188613
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.47066394
137P53_21459846_ChIP-Seq_SAOS-2_Human0.46975768
138CBP_21632823_ChIP-Seq_H3396_Human0.46375530
139TAF2_19829295_ChIP-Seq_ESCs_Human0.46171653
140PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.46150971
141SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.45787220
142FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.45486396
143E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.44591594
144SOX2_20726797_ChIP-Seq_SW620_Human0.44293340
145PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.44120452
146ERG_21242973_ChIP-ChIP_JURKAT_Human0.42812853
147GATA2_19941826_ChIP-Seq_K562_Human0.42424881
148ESR1_20079471_ChIP-ChIP_T-47D_Human0.42084352
149GATA1_19941826_ChIP-Seq_K562_Human0.41563526
150GATA1_19941827_ChIP-Seq_MEL_Mouse0.40905669
151NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.40019995
152BCAT_22108803_ChIP-Seq_LS180_Human0.39206211
153STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.39047729
154FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.37876842
155MYC_27129775_Chip-Seq_CORNEA_Mouse0.37728140
156CDX2_22108803_ChIP-Seq_LS180_Human0.36951999
157GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.36811703
158EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.36810370
159CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.36796872
160GATA3_24758297_ChIP-Seq_MCF-7_Human0.36470924
161CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.36392877
162SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.36188781
163RACK7_27058665_Chip-Seq_MCF-7_Human0.36067922
164ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.35335409

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.28961316
2MP0005360_urolithiasis7.64491331
3MP0005085_abnormal_gallbladder_physiolo6.40355331
4MP0005365_abnormal_bile_salt6.12740715
5MP0008875_abnormal_xenobiotic_pharmacok5.22472875
6MP0001984_abnormal_olfaction5.03766869
7MP0002736_abnormal_nociception_after4.35482051
8MP0003806_abnormal_nucleotide_metabolis4.07415756
9MP0003252_abnormal_bile_duct3.97601808
10MP0010329_abnormal_lipoprotein_level3.46384154
11MP0005423_abnormal_somatic_nervous3.41518287
12MP0009840_abnormal_foam_cell3.13613444
13MP0001968_abnormal_touch/_nociception2.97194673
14MP0005083_abnormal_biliary_tract2.92634849
15MP0005332_abnormal_amino_acid2.90395662
16MP0003195_calcinosis2.86953993
17MP0001666_abnormal_nutrient_absorption2.64252009
18MP0003880_abnormal_central_pattern2.55526716
19MP0004019_abnormal_vitamin_homeostasis2.36329474
20MP0003191_abnormal_cellular_cholesterol2.32159954
21MP0002138_abnormal_hepatobiliary_system2.12665996
22MP0000609_abnormal_liver_physiology2.11225676
23MP0002118_abnormal_lipid_homeostasis2.08033899
24MP0005551_abnormal_eye_electrophysiolog1.98685537
25MP0003868_abnormal_feces_composition1.93769460
26MP0005319_abnormal_enzyme/_coenzyme1.83004989
27MP0002734_abnormal_mechanical_nocicepti1.82590759
28MP0003183_abnormal_peptide_metabolism1.74607288
29MP0005310_abnormal_salivary_gland1.73064697
30MP0000751_myopathy1.70398573
31MP0004215_abnormal_myocardial_fiber1.67154261
32MP0001764_abnormal_homeostasis1.64154538
33MP0001486_abnormal_startle_reflex1.62102777
34MP0005584_abnormal_enzyme/coenzyme_acti1.58466469
35MP0004147_increased_porphyrin_level1.56692972
36MP0005451_abnormal_body_composition1.53179661
37MP0001986_abnormal_taste_sensitivity1.51723658
38MP0009643_abnormal_urine_homeostasis1.42702045
39MP0009697_abnormal_copulation1.40007770
40MP0003186_abnormal_redox_activity1.30724647
41MP0003011_delayed_dark_adaptation1.30513712
42MP0000538_abnormal_urinary_bladder1.24037370
43MP0001905_abnormal_dopamine_level1.19337600
44MP0003705_abnormal_hypodermis_morpholog1.16257881
45MP0001970_abnormal_pain_threshold1.15992058
46MP0000749_muscle_degeneration1.14883601
47MP0000598_abnormal_liver_morphology1.14574361
48MP0003656_abnormal_erythrocyte_physiolo1.12240660
49MP0001853_heart_inflammation1.11462114
50MP0005647_abnormal_sex_gland1.09114903
51MP0005636_abnormal_mineral_homeostasis1.08162535
52MP0008260_abnormal_autophagy1.07487541
53MP0009764_decreased_sensitivity_to1.02764052
54MP0000343_altered_response_to1.01962760
55MP0003136_yellow_coat_color1.00636132
56MP0000604_amyloidosis0.99019091
57MP0004233_abnormal_muscle_weight0.96301144
58MP0004272_abnormal_basement_membrane0.96027419
59MP0009763_increased_sensitivity_to0.95040771
60MP0002254_reproductive_system_inflammat0.92178465
61MP0008775_abnormal_heart_ventricle0.89515309
62MP0008469_abnormal_protein_level0.87325013
63MP0009642_abnormal_blood_homeostasis0.87276750
64MP0005253_abnormal_eye_physiology0.85834995
65MP0005670_abnormal_white_adipose0.84657416
66MP0006036_abnormal_mitochondrial_physio0.83498405
67MP0005084_abnormal_gallbladder_morpholo0.83399641
68MP0002876_abnormal_thyroid_physiology0.82107357
69MP0005408_hypopigmentation0.80656360
70MP0002653_abnormal_ependyma_morphology0.80008102
71MP0002272_abnormal_nervous_system0.79277531
72MP0008789_abnormal_olfactory_epithelium0.79204541
73MP0010368_abnormal_lymphatic_system0.78791501
74MP0005376_homeostasis/metabolism_phenot0.77290124
75MP0001756_abnormal_urination0.75936511
76MP0002078_abnormal_glucose_homeostasis0.75272922
77MP0009765_abnormal_xenobiotic_induced0.75210781
78MP0005023_abnormal_wound_healing0.75072604
79MP0001485_abnormal_pinna_reflex0.73019870
80MP0002822_catalepsy0.72004290
81MP0005220_abnormal_exocrine_pancreas0.70899313
82MP0002733_abnormal_thermal_nociception0.70750303
83MP0002971_abnormal_brown_adipose0.69507226
84MP0004036_abnormal_muscle_relaxation0.68198478
85MP0005535_abnormal_body_temperature0.67262119
86MP0005334_abnormal_fat_pad0.65929820
87MP0004130_abnormal_muscle_cell0.64823119
88MP0009053_abnormal_anal_canal0.64776584
89MP0003633_abnormal_nervous_system0.64582030
90MP0001661_extended_life_span0.64320033
91MP0005266_abnormal_metabolism0.63718158
92MP0003690_abnormal_glial_cell0.61379711
93MP0001664_abnormal_digestion0.60981520
94MP0002136_abnormal_kidney_physiology0.59992894
95MP0001529_abnormal_vocalization0.59268774
96MP0002090_abnormal_vision0.58239984
97MP0003329_amyloid_beta_deposits0.58184670
98MP0004270_analgesia0.57813461
99MP0006035_abnormal_mitochondrial_morpho0.57441722
100MP0001963_abnormal_hearing_physiology0.56216617
101MP0002132_abnormal_respiratory_system0.55878326
102MP0008058_abnormal_DNA_repair0.55670255
103MP0005448_abnormal_energy_balance0.52489653
104MP0002928_abnormal_bile_duct0.51518634
105MP0000639_abnormal_adrenal_gland0.51479547
106MP0005164_abnormal_response_to0.50451316
107MP0005395_other_phenotype0.49095746
108MP0004043_abnormal_pH_regulation0.48806524
109MP0003638_abnormal_response/metabolism_0.48540332
110MP0010234_abnormal_vibrissa_follicle0.46477370
111MP0008873_increased_physiological_sensi0.45062057
112MP0003718_maternal_effect0.44410432
113MP0005464_abnormal_platelet_physiology0.44366902
114MP0002796_impaired_skin_barrier0.43329006
115MP0005666_abnormal_adipose_tissue0.42787351
116MP0008874_decreased_physiological_sensi0.42388513
117MP0003724_increased_susceptibility_to0.42271758
118MP0004782_abnormal_surfactant_physiolog0.41687065
119MP0003953_abnormal_hormone_level0.41224908
120MP0005166_decreased_susceptibility_to0.40418622
121MP0003075_altered_response_to0.39421699
122MP0001765_abnormal_ion_homeostasis0.38662517
123MP0008872_abnormal_physiological_respon0.38455716
124MP0000230_abnormal_systemic_arterial0.38184825
125MP0003436_decreased_susceptibility_to0.36914528
126MP0002837_dystrophic_cardiac_calcinosis0.36336753
127MP0009672_abnormal_birth_weight0.35999841
128MP0009384_cardiac_valve_regurgitation0.35754381
129MP0005248_abnormal_Harderian_gland0.35098224
130MP0002168_other_aberrant_phenotype0.34746526
131MP0005058_abnormal_lysosome_morphology0.34645553
132MP0004381_abnormal_hair_follicle0.33850403
133MP0004264_abnormal_extraembryonic_tissu0.33215389
134MP0000579_abnormal_nail_morphology0.32220555
135MP0005167_abnormal_blood-brain_barrier0.32155357
136MP0009115_abnormal_fat_cell0.30612449
137MP0000249_abnormal_blood_vessel0.29449733
138MP0006082_CNS_inflammation0.28897903
139MP0001845_abnormal_inflammatory_respons0.28769725
140MP0002970_abnormal_white_adipose0.28054354
141MP0001243_abnormal_dermal_layer0.27051564
142MP0004883_abnormal_blood_vessel0.26857980

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.35913681
2Intrahepatic cholestasis (HP:0001406)7.17435903
3Deep venous thrombosis (HP:0002625)7.07195954
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.61608968
5Hypobetalipoproteinemia (HP:0003563)6.22030012
6Prolonged partial thromboplastin time (HP:0003645)6.21095080
7Xanthomatosis (HP:0000991)6.18600883
8Hyperlipoproteinemia (HP:0010980)5.43206861
9Congenital primary aphakia (HP:0007707)5.19941955
10Complement deficiency (HP:0004431)5.12217474
11Gait imbalance (HP:0002141)5.10047708
12Hyperammonemia (HP:0001987)4.65815572
13Hypolipoproteinemia (HP:0010981)4.63384966
14Joint hemorrhage (HP:0005261)4.56400560
15Nephrogenic diabetes insipidus (HP:0009806)4.54739983
16Medial flaring of the eyebrow (HP:0010747)4.52271496
17Hyperglycinemia (HP:0002154)4.43629141
18Epidermoid cyst (HP:0200040)4.42846980
19Abnormality of glutamine family amino acid metabolism (HP:0010902)4.42308602
20Ketosis (HP:0001946)4.35211634
21Abnormality of sulfur amino acid metabolism (HP:0004339)4.29990098
22Abnormality of aspartate family amino acid metabolism (HP:0010899)4.24955722
23Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.23652999
24Abnormality of methionine metabolism (HP:0010901)4.19915354
25Abnormality of the common coagulation pathway (HP:0010990)4.14938870
26Hyperglycinuria (HP:0003108)4.14818971
27Fat malabsorption (HP:0002630)4.06824340
28Hypoalphalipoproteinemia (HP:0003233)4.05128578
29Abnormality of glycine metabolism (HP:0010895)4.04712819
30Abnormality of serine family amino acid metabolism (HP:0010894)4.04712819
31Hypoglycemic coma (HP:0001325)3.82947234
32Poor coordination (HP:0002370)3.82394734
33Hemiplegia (HP:0002301)3.79930272
34Abnormality of pyrimidine metabolism (HP:0004353)3.76772806
35Abnormality of complement system (HP:0005339)3.72940813
36Conjugated hyperbilirubinemia (HP:0002908)3.67357297
37Abnormality of the intrinsic pathway (HP:0010989)3.54069035
38Abnormality of fatty-acid metabolism (HP:0004359)3.50121128
39Hypercholesterolemia (HP:0003124)3.45684194
40Action tremor (HP:0002345)3.45548451
41Abnormality of glycolysis (HP:0004366)3.44418057
42Vaginal atresia (HP:0000148)3.43817185
43Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.38428416
44Genital tract atresia (HP:0001827)3.30957385
45Hyperbilirubinemia (HP:0002904)3.28401679
46Abnormality of nucleobase metabolism (HP:0010932)3.21684206
47Ketoacidosis (HP:0001993)3.14754201
48Delayed CNS myelination (HP:0002188)3.12913628
49Abnormality of serum amino acid levels (HP:0003112)3.05786296
50Steatorrhea (HP:0002570)3.05509892
51Increased serum pyruvate (HP:0003542)2.98184585
52Hepatocellular carcinoma (HP:0001402)2.95511472
53Aplasia/Hypoplasia of the lens (HP:0008063)2.95256850
54Abnormality of purine metabolism (HP:0004352)2.94139907
55Gout (HP:0001997)2.92431839
56Bile duct proliferation (HP:0001408)2.89720324
57Abnormal biliary tract physiology (HP:0012439)2.89720324
58Left ventricular hypertrophy (HP:0001712)2.88567830
59Metabolic acidosis (HP:0001942)2.86592233
60Myocardial infarction (HP:0001658)2.83386674
61Spontaneous abortion (HP:0005268)2.80356841
62Hemiparesis (HP:0001269)2.80089381
63Abnormality of dicarboxylic acid metabolism (HP:0010995)2.77811661
64Dicarboxylic aciduria (HP:0003215)2.77811661
65CNS demyelination (HP:0007305)2.73901970
66Hepatocellular necrosis (HP:0001404)2.72983187
67Lethargy (HP:0001254)2.72257760
68Hypochromic microcytic anemia (HP:0004840)2.71993557
69Skin nodule (HP:0200036)2.69953024
70Vascular calcification (HP:0004934)2.67491173
71Systemic lupus erythematosus (HP:0002725)2.64260953
72Cerebral edema (HP:0002181)2.49946954
73Hepatic necrosis (HP:0002605)2.46419865
74Spastic diplegia (HP:0001264)2.45452049
75Irritability (HP:0000737)2.43946739
76Acanthocytosis (HP:0001927)2.43663534
77Neonatal onset (HP:0003623)2.41286803
78Hypoglycemic seizures (HP:0002173)2.40277111
79Abnormality of vitamin metabolism (HP:0100508)2.37447420
80Malnutrition (HP:0004395)2.37412092
81Cardiovascular calcification (HP:0011915)2.36912253
82Methylmalonic aciduria (HP:0012120)2.36859661
83Abnormal gallbladder morphology (HP:0012437)2.36009738
84Tetraplegia (HP:0002445)2.35261058
85Broad foot (HP:0001769)2.34307052
86Mitral stenosis (HP:0001718)2.32412660
87Cholecystitis (HP:0001082)2.30466781
88Abnormal gallbladder physiology (HP:0012438)2.30466781
89Cholelithiasis (HP:0001081)2.29591948
90Glomerulonephritis (HP:0000099)2.28357556
91Generalized aminoaciduria (HP:0002909)2.27737918
92Sensorimotor neuropathy (HP:0007141)2.24784998
93Alkalosis (HP:0001948)2.24382660
94Confusion (HP:0001289)2.23735964
95Nephritis (HP:0000123)2.22002309
96Enlarged kidneys (HP:0000105)2.20726196
97Abnormality of the vitamin B12 metabolism (HP:0004341)2.20026771
98Recurrent gram-negative bacterial infections (HP:0005420)2.19540786
99Exercise-induced myalgia (HP:0003738)2.19452553
100Vomiting (HP:0002013)2.19268749
101Esophageal varix (HP:0002040)2.18338970
102Late onset (HP:0003584)2.18323979
103Pancreatitis (HP:0001733)2.17942761
104Amyloidosis (HP:0011034)2.13193281
105Insidious onset (HP:0003587)2.12562879
106Termporal pattern (HP:0011008)2.12562879
107Brushfield spots (HP:0001088)2.11653208
108Rickets (HP:0002748)2.10113806
109Methylmalonic acidemia (HP:0002912)2.09273178
110Abnormal glucose tolerance (HP:0001952)2.05700665
111Abnormal cartilage morphology (HP:0002763)2.05193632
112Abnormality of proline metabolism (HP:0010907)2.04865048
113Hydroxyprolinuria (HP:0003080)2.04865048
114Ulnar claw (HP:0001178)2.04409861
115Increased purine levels (HP:0004368)2.03264068
116Hyperuricemia (HP:0002149)2.03264068
117Proximal tubulopathy (HP:0000114)2.03241014
118Type I transferrin isoform profile (HP:0003642)2.02958859
119Menorrhagia (HP:0000132)2.02580838
120Gingival bleeding (HP:0000225)2.02518399
121Abnormality of vitamin B metabolism (HP:0004340)2.00713967
122Opisthotonus (HP:0002179)1.99487775
123Thrombophlebitis (HP:0004418)1.98026101
124Abnormality of the gallbladder (HP:0005264)1.96297701
125Abnormal enzyme/coenzyme activity (HP:0012379)1.93717364
126Hyperinsulinemic hypoglycemia (HP:0000825)1.92521051
127Azoospermia (HP:0000027)1.90039498
128Glycosuria (HP:0003076)1.89700346
129Abnormality of urine glucose concentration (HP:0011016)1.89700346
130Hemorrhage of the eye (HP:0011885)1.89339367
131Hypophosphatemic rickets (HP:0004912)1.88779932
132Acute encephalopathy (HP:0006846)1.88376057
133Spastic tetraparesis (HP:0001285)1.87942272
134Poikilocytosis (HP:0004447)1.87141552
135Aplasia/Hypoplasia involving the musculature (HP:0001460)1.85675312
136Renal cortical cysts (HP:0000803)1.84982219
137Abnormality of iron homeostasis (HP:0011031)1.82475956
138Abnormality of transition element cation homeostasis (HP:0011030)1.81811716
139Fatigue (HP:0012378)1.74351468
140Mitochondrial inheritance (HP:0001427)1.72064517
141Large for gestational age (HP:0001520)1.71679987
142Abnormality of the vocal cords (HP:0008777)1.71054543
143Abnormal spermatogenesis (HP:0008669)1.70082859

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK29.62758703
2BCKDK7.16182227
3FGFR44.37930485
4ERN14.26907336
5SIK14.25035407
6TAOK33.48379633
7STK163.26283412
8CCNB13.03360787
9EIF2AK12.98304929
10ERBB42.85776759
11INSRR2.83276611
12MST1R2.65704563
13NEK62.33294940
14MUSK2.31670947
15SRPK12.26045719
16MAP2K42.17567504
17PKN22.08742108
18MAPK111.86014661
19EIF2AK31.83530436
20FLT31.69885680
21FRK1.68691198
22PIK3CG1.65524924
23TNIK1.64486533
24TRIB31.62192743
25LATS11.57153368
26TYK21.54479404
27ABL21.52982388
28TNK21.48073886
29PTK61.47356790
30EPHA21.44424020
31MAP3K71.37573962
32DAPK21.32724235
33NEK91.30564405
34GRK61.27493020
35STK38L1.25627039
36FGFR21.25412169
37KDR1.23931079
38MKNK21.22289413
39PRKAA21.16196137
40TTK1.14943310
41JAK21.14405566
42PINK11.11920809
43CDK81.09300417
44MAPKAPK31.09223103
45TBK11.08128459
46PTK2B1.06527135
47ERBB21.04593410
48MAP3K141.02290718
49BMPR1B0.99663543
50LMTK20.97220771
51MET0.97167504
52MAP2K30.95937021
53MAPK40.95306774
54NTRK20.91908033
55PIK3CA0.91759257
56MAPK150.91659565
57PRKCZ0.91191514
58JAK10.88134187
59PRKCE0.86675754
60MAP3K100.86511691
61GRK70.86231835
62MAP3K30.85091614
63EPHB10.84042646
64PLK20.82233545
65RIPK10.80051627
66PRKG20.76388617
67TIE10.75893684
68PRKACG0.74998987
69CAMK2G0.74971766
70MAPK120.74501831
71LIMK10.74484704
72CAMK2B0.73734370
73GSK3A0.73371253
74CAMK2D0.73256234
75CSK0.72678269
76MAP3K110.72157577
77DYRK1B0.71388350
78MAP2K60.69943225
79PRKAA10.69190258
80SGK30.69099217
81CDK60.68911126
82PRKACB0.68839109
83CAMK1D0.66481250
84WNK40.65444262
85FER0.64038250
86PRKACA0.63723860
87PTK20.63393775
88PDPK10.63221293
89VRK20.62755638
90WNK30.59616477
91IRAK30.57837243
92EPHA30.57835252
93MAP2K20.57536529
94NME10.57393406
95ERBB30.55658616
96TGFBR20.55156533
97IKBKE0.54666984
98MAPK70.52573203
99CSNK2A10.51677098
100RPS6KA50.50976027
101PRKCQ0.50839091
102MAP2K10.50201884
103SGK4940.49729684
104SGK2230.49729684
105EPHB20.48930033
106SGK20.48568213
107CSNK1G10.45310625
108FGFR30.44991729
109CSF1R0.44386953
110TRPM70.43326954
111GRK10.42465334
112PDK40.41634707
113PDK30.41634707
114MKNK10.40836498
115IGF1R0.40104183
116ICK0.39956276
117PDK10.39420935
118DYRK1A0.39024558
119SGK10.38668209
120EPHA40.38128117
121MAPKAPK50.37138824
122PKN10.37040357
123MAP3K130.36960826
124OXSR10.36774739
125CAMK2A0.36747584
126CLK10.36454283
127TAOK20.36314494
128FGR0.35812062
129AKT20.35548950
130MAP3K50.34601884
131PRKDC0.34471857
132PRKCG0.33932471
133STK100.32919907
134MTOR0.32079454
135MAP3K10.32071107
136PBK0.31501159
137RET0.31315814
138SRC0.30976615
139ADRBK10.30855104
140PRKCA0.30669514
141PAK30.30390484
142CSNK1D0.29981294
143MYLK0.29804081
144INSR0.29313022
145EGFR0.29043955
146CDK40.28746380
147CSNK2A20.27324363
148MAP3K20.27126619
149LRRK20.26164796
150CAMK40.25383798
151NME20.25100685
152OBSCN0.24969662
153ROCK20.24208900
154PIM20.24050308
155ADRBK20.23720854
156MAP3K60.22868678
157NEK10.21465161

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.37860631
2Nitrogen metabolism_Homo sapiens_hsa009103.44677027
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.41399189
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.32521641
5Arginine biosynthesis_Homo sapiens_hsa002202.98508355
6Tryptophan metabolism_Homo sapiens_hsa003802.70804243
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.66182346
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.64104333
9Complement and coagulation cascades_Homo sapiens_hsa046102.57458419
10Fatty acid degradation_Homo sapiens_hsa000712.50734282
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.50527758
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.44779550
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.33815251
14Butanoate metabolism_Homo sapiens_hsa006502.28597269
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.13565344
16Peroxisome_Homo sapiens_hsa041462.12256370
17Propanoate metabolism_Homo sapiens_hsa006401.98335942
18Chemical carcinogenesis_Homo sapiens_hsa052041.93730681
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.91912434
20Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.91022673
21Histidine metabolism_Homo sapiens_hsa003401.90713217
22PPAR signaling pathway_Homo sapiens_hsa033201.87893637
23Fatty acid metabolism_Homo sapiens_hsa012121.82033316
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.80318437
25Drug metabolism - other enzymes_Homo sapiens_hsa009831.72615294
26beta-Alanine metabolism_Homo sapiens_hsa004101.72237985
27Caffeine metabolism_Homo sapiens_hsa002321.69128725
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.68880388
29Retinol metabolism_Homo sapiens_hsa008301.67045587
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.66097739
31Sulfur metabolism_Homo sapiens_hsa009201.64252292
32Staphylococcus aureus infection_Homo sapiens_hsa051501.60870661
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.56903824
34Phenylalanine metabolism_Homo sapiens_hsa003601.56785350
35Bile secretion_Homo sapiens_hsa049761.55707506
36Selenocompound metabolism_Homo sapiens_hsa004501.55561866
37Pyruvate metabolism_Homo sapiens_hsa006201.43432004
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41499824
39Tyrosine metabolism_Homo sapiens_hsa003501.40792249
40Fatty acid elongation_Homo sapiens_hsa000621.33011225
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.31407085
42Starch and sucrose metabolism_Homo sapiens_hsa005001.30363797
43Folate biosynthesis_Homo sapiens_hsa007901.21465863
44Steroid biosynthesis_Homo sapiens_hsa001001.18738339
45Biosynthesis of amino acids_Homo sapiens_hsa012301.18189115
46Carbon metabolism_Homo sapiens_hsa012001.16372963
47ABC transporters_Homo sapiens_hsa020101.15487488
48Fat digestion and absorption_Homo sapiens_hsa049751.14628835
49Cyanoamino acid metabolism_Homo sapiens_hsa004601.11439866
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.09370622
51Sulfur relay system_Homo sapiens_hsa041221.01830215
52Maturity onset diabetes of the young_Homo sapiens_hsa049501.00580232
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99843344
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.98171825
55Arginine and proline metabolism_Homo sapiens_hsa003300.98140155
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92830066
57Vitamin digestion and absorption_Homo sapiens_hsa049770.91279327
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86627267
59Vitamin B6 metabolism_Homo sapiens_hsa007500.84674551
60Lysine degradation_Homo sapiens_hsa003100.80447617
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73349928
62Glutathione metabolism_Homo sapiens_hsa004800.73039902
63Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72656284
64Glycerolipid metabolism_Homo sapiens_hsa005610.70025018
65One carbon pool by folate_Homo sapiens_hsa006700.67393430
66N-Glycan biosynthesis_Homo sapiens_hsa005100.59810742
67Pentose phosphate pathway_Homo sapiens_hsa000300.58218758
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57940265
69Proteasome_Homo sapiens_hsa030500.57842630
70Metabolic pathways_Homo sapiens_hsa011000.47996910
71Fatty acid biosynthesis_Homo sapiens_hsa000610.47834821
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.42165728
73Fructose and mannose metabolism_Homo sapiens_hsa000510.31739572
74Prion diseases_Homo sapiens_hsa050200.31241572
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.29200798
76Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29026157
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.28982735
78Galactose metabolism_Homo sapiens_hsa000520.28122624
79Sphingolipid metabolism_Homo sapiens_hsa006000.27722185
80Pancreatic secretion_Homo sapiens_hsa049720.26870264
81Linoleic acid metabolism_Homo sapiens_hsa005910.23051705
82Insulin resistance_Homo sapiens_hsa049310.21227564
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.20986909
84Oxidative phosphorylation_Homo sapiens_hsa001900.20940236
85Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.20547649
86Other glycan degradation_Homo sapiens_hsa005110.20053403
87Glycerophospholipid metabolism_Homo sapiens_hsa005640.16410859
88Parkinsons disease_Homo sapiens_hsa050120.10381585
89Collecting duct acid secretion_Homo sapiens_hsa049660.09583401
90Glucagon signaling pathway_Homo sapiens_hsa049220.08426247
91Pertussis_Homo sapiens_hsa051330.05198463
92Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.02559223
93AMPK signaling pathway_Homo sapiens_hsa041520.01484738
94Alzheimers disease_Homo sapiens_hsa050100.01139313
95Homologous recombination_Homo sapiens_hsa034400.01062681
96Glutamatergic synapse_Homo sapiens_hsa047240.00728337
97Huntingtons disease_Homo sapiens_hsa050160.00111878
98Bladder cancer_Homo sapiens_hsa05219-0.2415451
99Ether lipid metabolism_Homo sapiens_hsa00565-0.2382599
100Protein digestion and absorption_Homo sapiens_hsa04974-0.2337160
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2286333
102Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1760620
103Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1721193
104Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1696562
105Hepatitis C_Homo sapiens_hsa05160-0.1654334
106African trypanosomiasis_Homo sapiens_hsa05143-0.1652355
107Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1642358
108Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1590843
109Mineral absorption_Homo sapiens_hsa04978-0.1537644
110Regulation of autophagy_Homo sapiens_hsa04140-0.1371137
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1308414
112Renin-angiotensin system_Homo sapiens_hsa04614-0.1304811
113Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1186910
114Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1151317
115Insulin signaling pathway_Homo sapiens_hsa04910-0.1101968
116Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0811985
117Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0314009
118Nicotine addiction_Homo sapiens_hsa05033-0.0182884

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