MCM6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* DNA strand elongation involved in DNA replication (GO:0006271)5.97940730
2* DNA unwinding involved in DNA replication (GO:0006268)5.89900933
3* DNA strand elongation (GO:0022616)5.67925520
4telomere maintenance via semi-conservative replication (GO:0032201)5.62136995
5* DNA replication initiation (GO:0006270)5.53345510
6telomere maintenance via recombination (GO:0000722)4.98327901
7mitotic recombination (GO:0006312)4.79174268
8DNA replication checkpoint (GO:0000076)4.64612969
9protein localization to kinetochore (GO:0034501)4.54253585
10nucleotide-excision repair, DNA gap filling (GO:0006297)4.40385883
11telomere maintenance via telomere lengthening (GO:0010833)4.38436278
12nucleobase biosynthetic process (GO:0046112)4.34080608
13ribosomal small subunit assembly (GO:0000028)4.33946670
14IMP biosynthetic process (GO:0006188)4.24392655
15DNA replication-dependent nucleosome organization (GO:0034723)4.22344746
16DNA replication-dependent nucleosome assembly (GO:0006335)4.22344746
17folic acid-containing compound biosynthetic process (GO:0009396)4.17568523
18heterochromatin organization (GO:0070828)4.15966048
19regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.04924401
20establishment of viral latency (GO:0019043)4.00096476
21formation of translation preinitiation complex (GO:0001731)3.95378624
22mitotic nuclear envelope disassembly (GO:0007077)3.93797380
23double-strand break repair via nonhomologous end joining (GO:0006303)3.93608317
24non-recombinational repair (GO:0000726)3.93608317
25purine nucleobase biosynthetic process (GO:0009113)3.89590059
26DNA ligation (GO:0006266)3.89589623
27IMP metabolic process (GO:0046040)3.89551848
28maturation of SSU-rRNA (GO:0030490)3.87652243
29nuclear pore organization (GO:0006999)3.84375510
30translesion synthesis (GO:0019985)3.81869242
31protein localization to chromosome, centromeric region (GO:0071459)3.81299920
32mitotic chromosome condensation (GO:0007076)3.75746684
33CENP-A containing nucleosome assembly (GO:0034080)3.73899625
34chromatin remodeling at centromere (GO:0031055)3.73542229
35* DNA duplex unwinding (GO:0032508)3.70857355
36nuclear pore complex assembly (GO:0051292)3.70587247
37* DNA geometric change (GO:0032392)3.69406148
38DNA synthesis involved in DNA repair (GO:0000731)3.69229605
39nuclear envelope disassembly (GO:0051081)3.64434330
40membrane disassembly (GO:0030397)3.64434330
41viral transcription (GO:0019083)3.62119351
42DNA replication-independent nucleosome organization (GO:0034724)3.61624430
43DNA replication-independent nucleosome assembly (GO:0006336)3.61624430
44translational termination (GO:0006415)3.59034850
45regulation of translational fidelity (GO:0006450)3.53423585
46mitotic metaphase plate congression (GO:0007080)3.51746325
47regulation of centriole replication (GO:0046599)3.43921993
48somatic hypermutation of immunoglobulin genes (GO:0016446)3.43193751
49somatic diversification of immune receptors via somatic mutation (GO:0002566)3.43193751
50negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.42067837
51telomere maintenance (GO:0000723)3.39780400
52telomere organization (GO:0032200)3.38196518
53translational elongation (GO:0006414)3.35576476
54postreplication repair (GO:0006301)3.34714025
55DNA deamination (GO:0045006)3.33694604
56mitotic sister chromatid segregation (GO:0000070)3.32110318
57mismatch repair (GO:0006298)3.26739878
58kinetochore organization (GO:0051383)3.25920788
59mitotic sister chromatid cohesion (GO:0007064)3.25263044
60negative regulation of RNA splicing (GO:0033119)3.24953611
61translational initiation (GO:0006413)3.24611995
62L-serine metabolic process (GO:0006563)3.24599225
63sister chromatid segregation (GO:0000819)3.23810257
64protein localization to chromosome (GO:0034502)3.22287971
65chromosome segregation (GO:0007059)3.21581534
66negative regulation of mRNA metabolic process (GO:1903312)3.20219648
67chromosome condensation (GO:0030261)3.19760517
68viral mRNA export from host cell nucleus (GO:0046784)3.18087886
69nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.18052104
70metaphase plate congression (GO:0051310)3.17416799
71ribosome biogenesis (GO:0042254)3.16340803
72ribosomal large subunit biogenesis (GO:0042273)3.16103966
73chromatin assembly or disassembly (GO:0006333)3.15751757
74attachment of spindle microtubules to kinetochore (GO:0008608)3.14766733
75regulation of chromosome segregation (GO:0051983)3.13816340
76negative regulation of chromosome segregation (GO:0051985)3.12157133
77histone exchange (GO:0043486)3.11647376
78DNA catabolic process, exonucleolytic (GO:0000738)3.11279719
79ribonucleoprotein complex biogenesis (GO:0022613)3.10795569
80regulation of double-strand break repair via homologous recombination (GO:0010569)3.10618978
81deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.10395144
82base-excision repair (GO:0006284)3.09850900
83chromatin assembly (GO:0031497)3.09482329
84* DNA conformation change (GO:0071103)3.09386758
85ribosome assembly (GO:0042255)3.09316502
86V(D)J recombination (GO:0033151)3.07692617
87ribosomal small subunit biogenesis (GO:0042274)3.06950261
88protein complex localization (GO:0031503)3.04896575
89regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.04838646
90establishment of integrated proviral latency (GO:0075713)3.03040440
91regulation of DNA endoreduplication (GO:0032875)3.01993898
92maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.01959279
93negative regulation of mitotic sister chromatid separation (GO:2000816)3.01366762
94negative regulation of sister chromatid segregation (GO:0033046)3.01366762
95negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.01366762
96negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.01366762
97negative regulation of mitotic sister chromatid segregation (GO:0033048)3.01366762
98regulation of histone H3-K9 methylation (GO:0051570)3.01131870
99dosage compensation (GO:0007549)3.00893164
100regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.99277162
101SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.99127146
102regulation of sister chromatid cohesion (GO:0007063)2.97421764
103synapsis (GO:0007129)2.97320101
104termination of RNA polymerase II transcription (GO:0006369)2.97216192
105regulation of nuclear cell cycle DNA replication (GO:0033262)2.96580359
106regulation of centrosome cycle (GO:0046605)2.96436949
107negative regulation of mRNA processing (GO:0050686)2.96352978
108establishment of chromosome localization (GO:0051303)2.96349177
109regulation of spindle organization (GO:0090224)2.95710733
110* mitotic cell cycle (GO:0000278)2.95227785
111transcription-coupled nucleotide-excision repair (GO:0006283)2.93804535
112rRNA processing (GO:0006364)2.92604506
113regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.91996885
114regulation of mitotic metaphase/anaphase transition (GO:0030071)2.91996885
115* G1/S transition of mitotic cell cycle (GO:0000082)2.90971014
116* cell cycle G1/S phase transition (GO:0044843)2.90971014
117DNA topological change (GO:0006265)2.89689876
118mitotic spindle checkpoint (GO:0071174)2.89620275
119cotranslational protein targeting to membrane (GO:0006613)2.89461196
120protein targeting to ER (GO:0045047)2.89156795
121DNA packaging (GO:0006323)2.88698726
122* DNA replication (GO:0006260)2.88472477
123pore complex assembly (GO:0046931)2.86526044
124ATP-dependent chromatin remodeling (GO:0043044)2.85409023
125nuclear envelope organization (GO:0006998)2.85177188
126mRNA splicing, via spliceosome (GO:0000398)2.84611042
127RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.84611042
128positive regulation of chromosome segregation (GO:0051984)2.84513497
129cellular protein complex disassembly (GO:0043624)2.83871233
130intra-S DNA damage checkpoint (GO:0031573)2.83432780
131rRNA metabolic process (GO:0016072)2.83280876
132RNA splicing, via transesterification reactions (GO:0000375)2.83243464
133meiotic chromosome segregation (GO:0045132)2.83242692
134spliceosomal snRNP assembly (GO:0000387)2.82666271
135viral life cycle (GO:0019058)2.81219483

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.13658638
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.02525541
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.95659628
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.78184009
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.07229468
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.80226969
7* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.61625150
8* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.56507922
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.47954078
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.41091358
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.39573076
12AR_21909140_ChIP-Seq_LNCAP_Human2.28886006
13* E2F1_21310950_ChIP-Seq_MCF-7_Human2.24583960
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.23732396
15* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19243746
16XRN2_22483619_ChIP-Seq_HELA_Human2.18905130
17GABP_17652178_ChIP-ChIP_JURKAT_Human2.16769228
18MYC_22102868_ChIP-Seq_BL_Human2.14935374
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.11843456
20* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.06885517
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.03327416
22* E2F7_22180533_ChIP-Seq_HELA_Human10.7244275
23VDR_23849224_ChIP-Seq_CD4+_Human1.95685148
24ELF1_17652178_ChIP-ChIP_JURKAT_Human1.90134421
25SALL1_21062744_ChIP-ChIP_HESCs_Human1.89965320
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.85196634
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84270458
28FOXP3_21729870_ChIP-Seq_TREG_Human1.83010903
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79040529
30* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.75689554
31* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.75083518
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73600129
33CIITA_25753668_ChIP-Seq_RAJI_Human1.72590289
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.71194139
35DCP1A_22483619_ChIP-Seq_HELA_Human1.70696283
36* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.67988883
37SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.67391816
38TTF2_22483619_ChIP-Seq_HELA_Human1.66359851
39NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.66010712
40GABP_19822575_ChIP-Seq_HepG2_Human1.64263689
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60113153
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58672841
43* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.55215321
44NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49935726
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46667666
46ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.46106005
47VDR_21846776_ChIP-Seq_THP-1_Human1.46015666
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.45470571
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.41344297
50ELK1_19687146_ChIP-ChIP_HELA_Human1.38684657
51SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.38139853
52KDM5A_27292631_Chip-Seq_BREAST_Human1.37646302
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.36367532
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34881300
55ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33775816
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29083307
57* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26786113
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24040606
59ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23369044
60SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.22411699
61E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20327218
62PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.18977675
63YY1_21170310_ChIP-Seq_MESCs_Mouse1.17420079
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.16956124
65TFEB_21752829_ChIP-Seq_HELA_Human1.14523855
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.13252060
67TP63_19390658_ChIP-ChIP_HaCaT_Human1.12171841
68PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.10595057
69SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.10476911
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09306760
71SPI1_23547873_ChIP-Seq_NB4_Human1.07275598
72DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.06141483
73GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03905663
74SRF_21415370_ChIP-Seq_HL-1_Mouse1.03436163
75CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02787996
76SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00914345
77PADI4_21655091_ChIP-ChIP_MCF-7_Human1.00154620
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97891846
79ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97761977
80NOTCH1_21737748_ChIP-Seq_TLL_Human0.97622477
81CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.95706374
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.95004379
83CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94727058
84E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.94186270
85KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93636249
86* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92316532
87TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91561577
88SCL_19346495_ChIP-Seq_HPC-7_Human0.91475637
89NANOG_16153702_ChIP-ChIP_HESCs_Human0.91311196
90* MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.90448272
91* MYB_21317192_ChIP-Seq_ERMYB_Mouse0.88831200
92RBPJ_22232070_ChIP-Seq_NCS_Mouse0.88404175
93MYC_18940864_ChIP-ChIP_HL60_Human0.87466386
94SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.86460653
95ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.86048366
96CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85933040
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.85902090
98ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.85803769
99NANOG_21062744_ChIP-ChIP_HESCs_Human0.85493732
100UTX_26944678_Chip-Seq_JUKART_Human0.85048841
101KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.84970186
102CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84418015
103MAF_26560356_Chip-Seq_TH1_Human0.84417581
104MYB_26560356_Chip-Seq_TH2_Human0.83790507
105IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.82916372
106MYB_26560356_Chip-Seq_TH1_Human0.82342234
107SOX2_16153702_ChIP-ChIP_HESCs_Human0.81560305
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.79001800
109CHD1_26751641_Chip-Seq_LNCaP_Human0.78319080
110* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.77779000
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.77484895
112RUNX1_22412390_ChIP-Seq_EML_Mouse0.77426004
113TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.76975129
114ZNF263_19887448_ChIP-Seq_K562_Human0.75003171
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.70870745
116NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.70533080
117DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.65959315
118SOX2_18692474_ChIP-Seq_MEFs_Mouse0.65273139

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0010094_abnormal_chromosome_stability4.89105544
2MP0003693_abnormal_embryo_hatching4.77914210
3MP0003111_abnormal_nucleus_morphology4.33055880
4MP0008057_abnormal_DNA_replication4.21573089
5MP0004957_abnormal_blastocyst_morpholog4.09868507
6MP0003077_abnormal_cell_cycle3.90518819
7MP0002396_abnormal_hematopoietic_system3.35224302
8MP0008058_abnormal_DNA_repair3.16411887
9MP0008007_abnormal_cellular_replicative2.87606179
10MP0010352_gastrointestinal_tract_polyps2.79561254
11MP0008932_abnormal_embryonic_tissue2.41487835
12MP0001730_embryonic_growth_arrest2.31180562
13MP0010307_abnormal_tumor_latency2.27902775
14MP0000350_abnormal_cell_proliferation2.27315793
15MP0009697_abnormal_copulation2.21850723
16MP0000490_abnormal_crypts_of2.13013794
17MP0004808_abnormal_hematopoietic_stem2.10902724
18MP0003123_paternal_imprinting2.07758430
19MP0008877_abnormal_DNA_methylation1.81570396
20MP0005397_hematopoietic_system_phenotyp1.68375440
21MP0001545_abnormal_hematopoietic_system1.68375440
22MP0003763_abnormal_thymus_physiology1.67498297
23MP0001697_abnormal_embryo_size1.66334808
24MP0002019_abnormal_tumor_incidence1.66075713
25MP0005380_embryogenesis_phenotype1.63040130
26MP0001672_abnormal_embryogenesis/_devel1.63040130
27* MP0002080_prenatal_lethality1.57420162
28MP0003786_premature_aging1.54374920
29MP0002398_abnormal_bone_marrow1.53011624
30MP0006035_abnormal_mitochondrial_morpho1.52860710
31MP0000313_abnormal_cell_death1.52505171
32MP0003984_embryonic_growth_retardation1.49792595
33MP0009333_abnormal_splenocyte_physiolog1.47900502
34MP0002088_abnormal_embryonic_growth/wei1.45834934
35MP0000703_abnormal_thymus_morphology1.45807019
36MP0002085_abnormal_embryonic_tissue1.40157006
37MP0002086_abnormal_extraembryonic_tissu1.39910058
38MP0004197_abnormal_fetal_growth/weight/1.39331715
39MP0006054_spinal_hemorrhage1.38820658
40MP0002722_abnormal_immune_system1.37390760
41MP0003567_abnormal_fetal_cardiomyocyte1.36192422
42MP0004185_abnormal_adipocyte_glucose1.36159592
43MP0002084_abnormal_developmental_patter1.35134414
44MP0006292_abnormal_olfactory_placode1.31890875
45MP0000689_abnormal_spleen_morphology1.31690128
46MP0009278_abnormal_bone_marrow1.30117860
47MP0005076_abnormal_cell_differentiation1.26452004
48MP0003941_abnormal_skin_development1.23906785
49MP0003937_abnormal_limbs/digits/tail_de1.23626816
50MP0002877_abnormal_melanocyte_morpholog1.22499783
51MP0003121_genomic_imprinting1.19552456
52* MP0002429_abnormal_blood_cell1.15832221
53MP0002009_preneoplasia1.12655544
54MP0001346_abnormal_lacrimal_gland1.10682313
55MP0000716_abnormal_immune_system1.05494573
56MP0001293_anophthalmia1.02660212
57MP0004233_abnormal_muscle_weight1.02208889
58MP0000858_altered_metastatic_potential1.00300822
59MP0002210_abnormal_sex_determination0.99441982
60MP0001286_abnormal_eye_development0.99383685
61MP0000537_abnormal_urethra_morphology0.95456942
62MP0001800_abnormal_humoral_immune0.95360581
63MP0002697_abnormal_eye_size0.95249005
64MP0001835_abnormal_antigen_presentation0.95006444
65MP0000566_synostosis0.94345962
66MP0000465_gastrointestinal_hemorrhage0.93960250
67MP0000428_abnormal_craniofacial_morphol0.92633758
68MP0003806_abnormal_nucleotide_metabolis0.91762799
69MP0002166_altered_tumor_susceptibility0.91432975
70MP0001145_abnormal_male_reproductive0.90778324
71MP0002420_abnormal_adaptive_immunity0.90436945
72MP0000685_abnormal_immune_system0.90382533
73MP0008260_abnormal_autophagy0.90274930
74MP0001819_abnormal_immune_cell0.88504265
75MP0000358_abnormal_cell_content/0.87504132
76MP0001661_extended_life_span0.86975374
77MP0005501_abnormal_skin_physiology0.85305840
78MP0002452_abnormal_antigen_presenting0.84350606
79MP0003119_abnormal_digestive_system0.84126124
80MP0005023_abnormal_wound_healing0.83414708
81MP0010030_abnormal_orbit_morphology0.82596006
82MP0002006_tumorigenesis0.82423208
83MP0001915_intracranial_hemorrhage0.81679454
84MP0000477_abnormal_intestine_morphology0.81445605
85MP0001853_heart_inflammation0.80951277
86MP0005671_abnormal_response_to0.80792104
87MP0003566_abnormal_cell_adhesion0.80505663
88MP0002405_respiratory_system_inflammati0.80149128
89MP0005384_cellular_phenotype0.79494696
90MP0003718_maternal_effect0.79419325
91MP0003221_abnormal_cardiomyocyte_apopto0.78352351
92MP0003186_abnormal_redox_activity0.78089504
93MP0009672_abnormal_birth_weight0.77958201
94MP0005174_abnormal_tail_pigmentation0.77324523
95MP0003890_abnormal_embryonic-extraembry0.76991830
96MP0005621_abnormal_cell_physiology0.76103227
97MP0002233_abnormal_nose_morphology0.75114120
98MP0003705_abnormal_hypodermis_morpholog0.74765725
99MP0001929_abnormal_gametogenesis0.74422398
100MP0002163_abnormal_gland_morphology0.73841721
101MP0000653_abnormal_sex_gland0.73068272
102MP0002095_abnormal_skin_pigmentation0.72878257
103MP0010155_abnormal_intestine_physiology0.72238597
104MP0002723_abnormal_immune_serum0.72223251
105MP0001873_stomach_inflammation0.72095188
106MP0008995_early_reproductive_senescence0.72084823
107MP0001727_abnormal_embryo_implantation0.71194161
108MP0003861_abnormal_nervous_system0.68612546
109MP0001119_abnormal_female_reproductive0.67735766
110MP0002075_abnormal_coat/hair_pigmentati0.67299393
111MP0002160_abnormal_reproductive_system0.67160368
112MP0003315_abnormal_perineum_morphology0.67114109
113MP0006036_abnormal_mitochondrial_physio0.64961237
114MP0003115_abnormal_respiratory_system0.64772320
115MP0003698_abnormal_male_reproductive0.64520956
116MP0005075_abnormal_melanosome_morpholog0.64144189
117MP0005464_abnormal_platelet_physiology0.64018269
118MP0000432_abnormal_head_morphology0.63571110
119MP0001188_hyperpigmentation0.63463039
120MP0002111_abnormal_tail_morphology0.63095626
121MP0009703_decreased_birth_body0.62234120
122MP0009053_abnormal_anal_canal0.62091619
123MP0001881_abnormal_mammary_gland0.60723994
124MP0001849_ear_inflammation0.60630136
125MP0003935_abnormal_craniofacial_develop0.60430615
126MP0003448_altered_tumor_morphology0.60213284
127MP0003699_abnormal_female_reproductive0.60166898
128MP0002796_impaired_skin_barrier0.59917432
129MP0005025_abnormal_response_to0.59845496
130MP0002092_abnormal_eye_morphology0.59694659
131MP0004147_increased_porphyrin_level0.58700436
132MP0002161_abnormal_fertility/fecundity0.58644966
133MP0003943_abnormal_hepatobiliary_system0.58281602
134MP0009379_abnormal_foot_pigmentation0.57730810
135MP0005394_taste/olfaction_phenotype0.56046985
136MP0005499_abnormal_olfactory_system0.56046985
137MP0008789_abnormal_olfactory_epithelium0.55071823
138MP0002132_abnormal_respiratory_system0.54206667

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.01124112
2Reticulocytopenia (HP:0001896)4.29936931
3Abnormality of cells of the erythroid lineage (HP:0012130)4.13946199
4Abnormality of cochlea (HP:0000375)4.08104753
5Abnormal number of erythroid precursors (HP:0012131)4.03864470
6Chromsome breakage (HP:0040012)4.01321943
7Colon cancer (HP:0003003)3.76529396
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.68097165
9Ependymoma (HP:0002888)3.54683499
10Medulloblastoma (HP:0002885)3.47839051
11Selective tooth agenesis (HP:0001592)3.37495946
12Abnormality of chromosome stability (HP:0003220)3.34660007
13Oral leukoplakia (HP:0002745)3.33794118
14Agnosia (HP:0010524)3.30197368
15Breast hypoplasia (HP:0003187)3.23031808
16Aplastic anemia (HP:0001915)3.09241884
17Thrombocytosis (HP:0001894)3.03508575
18Abnormality of the preputium (HP:0100587)2.99669055
19Morphological abnormality of the inner ear (HP:0011390)2.97922528
20Microvesicular hepatic steatosis (HP:0001414)2.94583827
21Meckel diverticulum (HP:0002245)2.91304215
22Patellar aplasia (HP:0006443)2.89594593
23Myelodysplasia (HP:0002863)2.89345085
24Abnormality of the labia minora (HP:0012880)2.88808167
25Nephroblastoma (Wilms tumor) (HP:0002667)2.85787699
26Abnormality of the ileum (HP:0001549)2.81794545
27Aplasia/Hypoplasia of the uvula (HP:0010293)2.77365163
28Basal cell carcinoma (HP:0002671)2.76156282
29Aplasia/Hypoplasia of the patella (HP:0006498)2.68644771
30Embryonal renal neoplasm (HP:0011794)2.65131437
31Pallor (HP:0000980)2.64376363
32Rhabdomyosarcoma (HP:0002859)2.60888059
33Abnormality of the anterior horn cell (HP:0006802)2.59758869
34Degeneration of anterior horn cells (HP:0002398)2.59758869
35IgM deficiency (HP:0002850)2.59246049
3611 pairs of ribs (HP:0000878)2.57649020
37Increased nuchal translucency (HP:0010880)2.55257858
38Neoplasm of the pancreas (HP:0002894)2.54618272
39Absent thumb (HP:0009777)2.53200211
40Small intestinal stenosis (HP:0012848)2.49843954
41Duodenal stenosis (HP:0100867)2.49843954
42Facial cleft (HP:0002006)2.47205169
43Proximal placement of thumb (HP:0009623)2.46564133
44Progressive muscle weakness (HP:0003323)2.46335570
45Macrocytic anemia (HP:0001972)2.46219965
46Abnormal number of incisors (HP:0011064)2.43904038
47Bone marrow hypocellularity (HP:0005528)2.40898276
48Microretrognathia (HP:0000308)2.39668791
49Deviation of the thumb (HP:0009603)2.36110329
50Broad distal phalanx of finger (HP:0009836)2.35864426
51Amaurosis fugax (HP:0100576)2.35378571
52Calcaneovalgus deformity (HP:0001848)2.34242404
53Cortical dysplasia (HP:0002539)2.34076130
54Deep philtrum (HP:0002002)2.32632190
55Premature graying of hair (HP:0002216)2.31521612
56Diastasis recti (HP:0001540)2.30829637
57Lymphoma (HP:0002665)2.30501684
58Abnormality of the carotid arteries (HP:0005344)2.28938205
59High pitched voice (HP:0001620)2.25836896
60Slender long bone (HP:0003100)2.25615079
61Rough bone trabeculation (HP:0100670)2.25292565
62Astrocytoma (HP:0009592)2.18840168
63Abnormality of the astrocytes (HP:0100707)2.18840168
64Volvulus (HP:0002580)2.18821533
65Atresia of the external auditory canal (HP:0000413)2.18127828
66Choanal atresia (HP:0000453)2.17267110
67Deep palmar crease (HP:0006191)2.17173154
68Horseshoe kidney (HP:0000085)2.16695620
69Sloping forehead (HP:0000340)2.16384841
70Tracheoesophageal fistula (HP:0002575)2.14783514
71Short 4th metacarpal (HP:0010044)2.14307563
72Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.14307563
73Prominent nose (HP:0000448)2.13981141
74Carpal bone hypoplasia (HP:0001498)2.13919407
75Ectopic kidney (HP:0000086)2.12011134
76Overriding aorta (HP:0002623)2.11333103
77High anterior hairline (HP:0009890)2.11017357
78Impulsivity (HP:0100710)2.07150876
79Cellular immunodeficiency (HP:0005374)2.05688967
80Abnormality of the duodenum (HP:0002246)2.04297406
81Cafe-au-lait spot (HP:0000957)2.04181418
82Glioma (HP:0009733)2.03753926
83Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.03499293
84Squamous cell carcinoma (HP:0002860)2.02944585
85Short middle phalanx of the 5th finger (HP:0004220)2.02786434
86Aplasia/Hypoplasia of the sacrum (HP:0008517)2.02294436
87Arteriovenous malformation (HP:0100026)2.02082446
88Duplication of thumb phalanx (HP:0009942)2.00399601
89Neoplasm of the oral cavity (HP:0100649)2.00331835
90Deformed tarsal bones (HP:0008119)1.99788522
91Neoplasm of striated muscle (HP:0009728)1.99338322
92Abnormality of lateral ventricle (HP:0030047)1.95493319
93Clubbing of toes (HP:0100760)1.95062777
94Absent radius (HP:0003974)1.93232095
95Missing ribs (HP:0000921)1.92045759
96Abnormality of reticulocytes (HP:0004312)1.91789574
97Irregular epiphyses (HP:0010582)1.91208539
98Acute myeloid leukemia (HP:0004808)1.91195869
99Neoplasm of the colon (HP:0100273)1.90434954
100Embryonal neoplasm (HP:0002898)1.89178184
101Abnormality of the septum pellucidum (HP:0007375)1.88447890
102Abnormality of glycolysis (HP:0004366)1.88077813
103Chin dimple (HP:0010751)1.87897078
104Chronic otitis media (HP:0000389)1.86989675
105Microglossia (HP:0000171)1.86945143
106Aplasia/Hypoplasia of the sternum (HP:0006714)1.86783523
107Hyperacusis (HP:0010780)1.86726457
108Overlapping toe (HP:0001845)1.86681882
109Abnormality of the calcaneus (HP:0008364)1.86633572
110Abnormality of T cells (HP:0002843)1.86253252
111Abnormality of T cell physiology (HP:0011840)1.86197650
112Abnormal lung lobation (HP:0002101)1.85592924
113Absent epiphyses (HP:0010577)1.85421438
114Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.85421438
115Pancytopenia (HP:0001876)1.83307058
116Abnormality of DNA repair (HP:0003254)1.82966964
117Short thumb (HP:0009778)1.82286686
118Acute lymphatic leukemia (HP:0006721)1.82184120
119Duplicated collecting system (HP:0000081)1.82073459
120Progressive external ophthalmoplegia (HP:0000590)1.82040147
121Recurrent viral infections (HP:0004429)1.81903684
122Hypoplasia of the capital femoral epiphysis (HP:0003090)1.81883731
123Multiple enchondromatosis (HP:0005701)1.81562724
124Petechiae (HP:0000967)1.78647043
125Abnormality of B cell number (HP:0010975)1.78368695
126B lymphocytopenia (HP:0010976)1.78368695
127Biliary tract neoplasm (HP:0100574)1.78288181
128Trismus (HP:0000211)1.77972146
129Absent forearm bone (HP:0003953)1.77285571
130Aplasia involving forearm bones (HP:0009822)1.77285571
131Poikiloderma (HP:0001029)1.76947165
132Absent septum pellucidum (HP:0001331)1.76701456
133Triphalangeal thumb (HP:0001199)1.76126233
134Asplenia (HP:0001746)1.75948158
135Abnormality of the fingertips (HP:0001211)1.72917158
136Spastic diplegia (HP:0001264)1.72705650
137Premature ovarian failure (HP:0008209)1.72226132
138Glossoptosis (HP:0000162)1.71683127

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.21180557
2WEE14.28863125
3BUB13.39968406
4VRK22.94647157
5NEK22.82594158
6EEF2K2.61226623
7PBK2.47407948
8EIF2AK12.40601523
9ACVR1B2.40437040
10SMG12.38141516
11PASK2.31174108
12TSSK62.17010420
13STK38L2.16873367
14TAF12.15763290
15TTK1.97374161
16NEK11.95125626
17BRSK21.95046779
18ATR1.93279215
19RPS6KB21.92081834
20NME21.88624929
21PNCK1.87237119
22CDK71.86154645
23SRPK11.85814748
24SCYL21.80054039
25TGFBR11.75156371
26TESK21.73648431
27PLK11.70550859
28MAP4K11.67357002
29PKN21.63720649
30MKNK11.59941611
31VRK11.58387146
32MAP3K101.58385669
33RPS6KA41.58284760
34AURKB1.57086287
35CDK41.57064595
36EIF2AK31.54638220
37DYRK31.53186944
38CCNB11.51884106
39STK101.51404171
40CDK121.50784314
41MAP3K81.40428035
42STK161.39590095
43PLK41.36269635
44TLK11.33171738
45FLT31.32450090
46CHEK21.27096964
47BRSK11.23803238
48CHEK11.17521540
49PAK41.12659528
50STK41.09572676
51PLK31.08637817
52CDK191.05956552
53LRRK21.03678242
54BTK0.99893350
55AURKA0.99181615
56PIM10.95157110
57CDK80.92194641
58MAP2K30.91366104
59ATM0.87006454
60KIT0.86749430
61KDR0.86365197
62CDK20.84539497
63MKNK20.84046791
64CDK60.82865966
65CLK10.77091827
66BRD40.76383588
67MST40.72822796
68TEC0.69946319
69GRK60.69633068
70JAK30.69599766
71PIM20.68822354
72ALK0.68071072
73CSF1R0.64441417
74NME10.63787491
75TRIB30.63386621
76CSNK2A20.63264796
77BRAF0.61063771
78NUAK10.60405743
79CAMK1G0.59449658
80MAPKAPK30.58116774
81CDK10.57545866
82ZAP700.57348211
83TESK10.56748405
84MAP3K110.55500873
85CSNK2A10.55206579
86ZAK0.54626593
87ERBB40.53391002
88PAK10.52804383
89CDK30.52208674
90CDK11A0.51097909
91WNK10.50464089
92MAPKAPK50.50420467
93CDK90.49641862
94MELK0.49411890
95CSNK1E0.47676989
96MAPK110.45583978
97EPHA20.43270922
98CDK150.42677204
99CDK180.41084966
100EIF2AK20.40458403
101TYK20.40436039
102STK30.39945007
103RPS6KA50.39890866
104FGFR10.38947792
105CDK140.38410011
106DAPK10.38149635
107PDK20.36945342
108MTOR0.35286175
109CSNK1G10.34409445
110BLK0.34335489
111PAK20.33847645
112NEK90.33434436
113CSNK1G30.33136440
114PRKDC0.31830788
115LYN0.31774992
116AKT20.31754455
117ILK0.31645138
118SYK0.31615612
119PLK20.31224114
120RAF10.28963429
121BMX0.28612545
122LCK0.27499054
123GSK3B0.27227399
124KSR20.27191941
125ITK0.27148486
126TTN0.26555926
127YES10.25204999
128MAPK90.23287248
129MAPK140.23024526
130TAOK20.22044042
131CSNK1D0.21813389
132RPS6KB10.21357529
133TRIM280.21193205
134CSNK1A1L0.20967829
135ICK0.20905195
136MAP3K90.19797891

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030306.04388659
2Mismatch repair_Homo sapiens_hsa034304.95140694
3Base excision repair_Homo sapiens_hsa034103.44567484
4Homologous recombination_Homo sapiens_hsa034403.20110834
5Spliceosome_Homo sapiens_hsa030403.12940867
6Nucleotide excision repair_Homo sapiens_hsa034203.00688254
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.99174015
8Ribosome_Homo sapiens_hsa030102.95172188
9* Cell cycle_Homo sapiens_hsa041102.85602249
10One carbon pool by folate_Homo sapiens_hsa006702.81550503
11RNA transport_Homo sapiens_hsa030132.79234074
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.33605792
13Non-homologous end-joining_Homo sapiens_hsa034502.32167395
14Proteasome_Homo sapiens_hsa030502.31635581
15Pyrimidine metabolism_Homo sapiens_hsa002402.28257956
16RNA polymerase_Homo sapiens_hsa030202.24652841
17Fanconi anemia pathway_Homo sapiens_hsa034602.21559986
18RNA degradation_Homo sapiens_hsa030181.71027606
19p53 signaling pathway_Homo sapiens_hsa041151.58755507
20mRNA surveillance pathway_Homo sapiens_hsa030151.57819164
21Basal transcription factors_Homo sapiens_hsa030221.32332622
22Systemic lupus erythematosus_Homo sapiens_hsa053221.29351464
23Antigen processing and presentation_Homo sapiens_hsa046121.21146916
24Purine metabolism_Homo sapiens_hsa002301.12494186
25Viral carcinogenesis_Homo sapiens_hsa052031.10170554
26Herpes simplex infection_Homo sapiens_hsa051681.10007448
27Epstein-Barr virus infection_Homo sapiens_hsa051691.08563367
28Pyruvate metabolism_Homo sapiens_hsa006201.08149768
29Primary immunodeficiency_Homo sapiens_hsa053401.03259122
30Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.98737141
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.96899281
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96772856
33Pentose phosphate pathway_Homo sapiens_hsa000300.93214282
34HTLV-I infection_Homo sapiens_hsa051660.89711915
35Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.81877111
36Oocyte meiosis_Homo sapiens_hsa041140.80818550
37Biosynthesis of amino acids_Homo sapiens_hsa012300.79887220
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78166538
39Cyanoamino acid metabolism_Homo sapiens_hsa004600.77097083
40Folate biosynthesis_Homo sapiens_hsa007900.76717259
41Legionellosis_Homo sapiens_hsa051340.75729749
42Small cell lung cancer_Homo sapiens_hsa052220.75142947
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74904809
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73686950
45Selenocompound metabolism_Homo sapiens_hsa004500.73185490
46Thyroid cancer_Homo sapiens_hsa052160.70070938
47MicroRNAs in cancer_Homo sapiens_hsa052060.68200716
48Cysteine and methionine metabolism_Homo sapiens_hsa002700.66999116
49Measles_Homo sapiens_hsa051620.66897318
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.66765115
51Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64783331
52N-Glycan biosynthesis_Homo sapiens_hsa005100.62328175
53Chronic myeloid leukemia_Homo sapiens_hsa052200.61038712
54Sulfur relay system_Homo sapiens_hsa041220.60531866
55Vitamin B6 metabolism_Homo sapiens_hsa007500.60380708
56Hepatitis B_Homo sapiens_hsa051610.59560329
57Propanoate metabolism_Homo sapiens_hsa006400.58943539
58Huntingtons disease_Homo sapiens_hsa050160.58554883
59Apoptosis_Homo sapiens_hsa042100.57535517
60Fatty acid elongation_Homo sapiens_hsa000620.56587333
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54850496
62Colorectal cancer_Homo sapiens_hsa052100.53257798
63Shigellosis_Homo sapiens_hsa051310.52409731
64Parkinsons disease_Homo sapiens_hsa050120.50866585
65Steroid biosynthesis_Homo sapiens_hsa001000.49888709
66NF-kappa B signaling pathway_Homo sapiens_hsa040640.48056732
67Alcoholism_Homo sapiens_hsa050340.45868814
68Hematopoietic cell lineage_Homo sapiens_hsa046400.45653216
69Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44850864
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43867697
71Viral myocarditis_Homo sapiens_hsa054160.43597463
72Carbon metabolism_Homo sapiens_hsa012000.42773115
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.42169268
74Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.41743883
75Acute myeloid leukemia_Homo sapiens_hsa052210.38466779
76Non-small cell lung cancer_Homo sapiens_hsa052230.36402809
77B cell receptor signaling pathway_Homo sapiens_hsa046620.36335773
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.36127393
79Notch signaling pathway_Homo sapiens_hsa043300.35993513
80Influenza A_Homo sapiens_hsa051640.35670963
81Bladder cancer_Homo sapiens_hsa052190.35454756
82Central carbon metabolism in cancer_Homo sapiens_hsa052300.34790210
83Wnt signaling pathway_Homo sapiens_hsa043100.34106597
84Leishmaniasis_Homo sapiens_hsa051400.33673851
85Hedgehog signaling pathway_Homo sapiens_hsa043400.33639488
86Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33349433
87Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.33167898
88Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32500941
89Glutathione metabolism_Homo sapiens_hsa004800.32249576
90Pancreatic cancer_Homo sapiens_hsa052120.32135432
91RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31304307
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30647849
93HIF-1 signaling pathway_Homo sapiens_hsa040660.29456161
94Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.28308431
95Metabolic pathways_Homo sapiens_hsa011000.27754461
96TGF-beta signaling pathway_Homo sapiens_hsa043500.27737403
97Pathways in cancer_Homo sapiens_hsa052000.26905530
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26630328
99Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.26547502
100NOD-like receptor signaling pathway_Homo sapiens_hsa046210.26504029
101Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.25997735
102Intestinal immune network for IgA production_Homo sapiens_hsa046720.24916530
103Galactose metabolism_Homo sapiens_hsa000520.23544417
104Leukocyte transendothelial migration_Homo sapiens_hsa046700.23195741
105Renin-angiotensin system_Homo sapiens_hsa046140.22541160
106Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.21954971
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.21710128
108Protein export_Homo sapiens_hsa030600.21155522
109Basal cell carcinoma_Homo sapiens_hsa052170.21094492
110Lysine degradation_Homo sapiens_hsa003100.20681901
111Oxidative phosphorylation_Homo sapiens_hsa001900.19920622
1122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.19177288
113Hippo signaling pathway_Homo sapiens_hsa043900.19092084
114Jak-STAT signaling pathway_Homo sapiens_hsa046300.18800606
115T cell receptor signaling pathway_Homo sapiens_hsa046600.18553875
116Fatty acid metabolism_Homo sapiens_hsa012120.18484824
117Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.18320049
118Melanoma_Homo sapiens_hsa052180.17170930
119Prostate cancer_Homo sapiens_hsa052150.17073939
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16709933
121mTOR signaling pathway_Homo sapiens_hsa041500.16039186
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.15792901
123Fructose and mannose metabolism_Homo sapiens_hsa000510.15454046
124Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.15405692
125Toxoplasmosis_Homo sapiens_hsa051450.14995571
126Arginine and proline metabolism_Homo sapiens_hsa003300.13346428
127Adherens junction_Homo sapiens_hsa045200.12840683

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