MBD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.70061330
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.70061330
3antigen processing and presentation of endogenous antigen (GO:0019883)5.31844186
4positive regulation of gamma-delta T cell activation (GO:0046645)4.22942516
5response to peptidoglycan (GO:0032494)3.97540470
6detection of other organism (GO:0098543)3.86122064
7macrophage activation involved in immune response (GO:0002281)3.80494413
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.78893364
9positive thymic T cell selection (GO:0045059)3.77195634
10regulation of gamma-delta T cell differentiation (GO:0045586)3.69574532
11detection of bacterium (GO:0016045)3.68808341
12negative regulation of interleukin-12 production (GO:0032695)3.55351674
13positive regulation of histone deacetylation (GO:0031065)3.49470678
14immunoglobulin mediated immune response (GO:0016064)3.42886905
15negative regulation of erythrocyte differentiation (GO:0045647)3.42001425
16negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.41965913
17negative regulation of cell killing (GO:0031342)3.41965913
18regulation of gamma-delta T cell activation (GO:0046643)3.40894669
19positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.39833904
20detection of external biotic stimulus (GO:0098581)3.36559464
21detection of molecule of bacterial origin (GO:0032490)3.33546879
22germinal center formation (GO:0002467)3.32626450
23regulation of interleukin-12 biosynthetic process (GO:0045075)3.31911108
24JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.29216205
25lipopolysaccharide-mediated signaling pathway (GO:0031663)3.28459152
26thymic T cell selection (GO:0045061)3.22623573
27negative T cell selection (GO:0043383)3.17771984
28negative thymic T cell selection (GO:0045060)3.14958858
29leukocyte aggregation (GO:0070486)3.10260523
30growth hormone receptor signaling pathway (GO:0060396)3.07116961
31NIK/NF-kappaB signaling (GO:0038061)3.06554504
32regulation of dendritic cell antigen processing and presentation (GO:0002604)3.05297872
33regulation of B cell receptor signaling pathway (GO:0050855)3.04013085
34positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.03617724
35protein localization to endosome (GO:0036010)3.00863981
36positive T cell selection (GO:0043368)3.00557036
37response to host immune response (GO:0052572)2.98802078
38response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.98802078
39T-helper 1 type immune response (GO:0042088)2.98002555
40negative regulation of T cell mediated immunity (GO:0002710)2.95926498
41regulation of T cell tolerance induction (GO:0002664)2.93453598
42response to host (GO:0075136)2.92690428
43response to host defenses (GO:0052200)2.92690428
44response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.92690428
45myeloid dendritic cell differentiation (GO:0043011)2.91029907
46T cell selection (GO:0045058)2.87581771
47detection of biotic stimulus (GO:0009595)2.86701793
48Arp2/3 complex-mediated actin nucleation (GO:0034314)2.83455053
49defense response to protozoan (GO:0042832)2.80534579
50tolerance induction (GO:0002507)2.79320863
51myeloid dendritic cell activation (GO:0001773)2.77631924
52positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.76824515
53B cell homeostasis (GO:0001782)2.75822960
54negative regulation of lymphocyte mediated immunity (GO:0002707)2.75677030
55hepatocyte apoptotic process (GO:0097284)2.73303248
56response to protozoan (GO:0001562)2.72333607
57cellular response to zinc ion (GO:0071294)2.72104177
58positive regulation by organism of defense response of other organism involved in symbiotic interact2.71703348
59modulation by symbiont of host immune response (GO:0052553)2.71703348
60positive regulation by symbiont of host defense response (GO:0052509)2.71703348
61modulation by symbiont of host defense response (GO:0052031)2.71703348
62modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.71703348
63modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.71703348
64regulation of necroptotic process (GO:0060544)2.70705545
65cytidine metabolic process (GO:0046087)2.69815674
66cytidine catabolic process (GO:0006216)2.69815674
67cytidine deamination (GO:0009972)2.69815674
68positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.68960285
69cellular response to growth hormone stimulus (GO:0071378)2.64604506
70B cell mediated immunity (GO:0019724)2.64281698
71regulation of T-helper 2 cell differentiation (GO:0045628)2.63963041
72myeloid cell activation involved in immune response (GO:0002275)2.63158783
73regulation of antigen processing and presentation (GO:0002577)2.62954917
74T cell migration (GO:0072678)2.61505920
75positive regulation of cellular amide metabolic process (GO:0034250)2.60638805
76regulation of interferon-beta biosynthetic process (GO:0045357)2.59942463
77positive regulation of type 2 immune response (GO:0002830)2.58596296
78macrophage activation (GO:0042116)2.57757291
79CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.56699183
80regulation of T-helper 1 cell differentiation (GO:0045625)2.56113007
81negative regulation of leukocyte mediated immunity (GO:0002704)2.56085256
82positive regulation of lamellipodium assembly (GO:0010592)2.54475389
83regulation of mast cell degranulation (GO:0043304)2.54396608
84cellular response to interferon-gamma (GO:0071346)2.53970020
85desmosome organization (GO:0002934)2.53935150
86cellular response to thyroid hormone stimulus (GO:0097067)2.52515436
87positive regulation of Cdc42 GTPase activity (GO:0043089)2.52390744
88response to type I interferon (GO:0034340)2.52247498
89negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.51614022
90regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.51453477
91response to interleukin-15 (GO:0070672)2.50354906
92establishment of endothelial barrier (GO:0061028)2.49520892
93leukocyte cell-cell adhesion (GO:0007159)2.48678953
94negative regulation of toll-like receptor signaling pathway (GO:0034122)2.48538978
95microglial cell activation (GO:0001774)2.47725400
96positive regulation of p38MAPK cascade (GO:1900745)2.46956303
97production of molecular mediator involved in inflammatory response (GO:0002532)2.46218532
98regulation of macrophage cytokine production (GO:0010935)2.46205008
99Golgi transport vesicle coating (GO:0048200)2.45739370
100COPI coating of Golgi vesicle (GO:0048205)2.45739370
101positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.45495110
102positive regulation of interferon-alpha production (GO:0032727)2.45237915
103sequestering of metal ion (GO:0051238)2.43535435
104positive regulation of protein deacetylation (GO:0090312)2.43508926
105T cell costimulation (GO:0031295)2.43181615
106pinocytosis (GO:0006907)2.42795447
107hemidesmosome assembly (GO:0031581)2.41070641
108cellular response to type I interferon (GO:0071357)2.41001182
109type I interferon signaling pathway (GO:0060337)2.41001182
110regulation of B cell differentiation (GO:0045577)2.39979908
111regulation of type I interferon-mediated signaling pathway (GO:0060338)2.39632742
112regulation of interferon-alpha production (GO:0032647)2.38545800
113negative regulation of bone resorption (GO:0045779)2.37601944
114positive regulation of natural killer cell differentiation (GO:0032825)2.36899572
115lymphocyte costimulation (GO:0031294)2.36562986
116antigen processing and presentation via MHC class Ib (GO:0002475)2.36327378
117neutrophil activation involved in immune response (GO:0002283)2.35497694
118natural killer cell differentiation (GO:0001779)2.35325435
119interferon-gamma production (GO:0032609)2.34846081
120low-density lipoprotein particle clearance (GO:0034383)2.34570578
121B cell receptor signaling pathway (GO:0050853)2.30987181
122negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.30784850
123pyrimidine ribonucleoside catabolic process (GO:0046133)2.29588059
124regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.29522919
125positive regulation of B cell differentiation (GO:0045579)2.28922671
126regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.28737653
127positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.24343924
128positive regulation of isotype switching (GO:0045830)2.23004798
129regulation of cholesterol storage (GO:0010885)2.22753213
130response to laminar fluid shear stress (GO:0034616)2.22502431
131regulation of tolerance induction (GO:0002643)2.20403149
132negative regulation of stress fiber assembly (GO:0051497)2.19998629
133positive regulation of macrophage differentiation (GO:0045651)2.19938697
134positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.19507036
135regulation of response to interferon-gamma (GO:0060330)2.19441648
136response to muramyl dipeptide (GO:0032495)2.18900855
137cellular extravasation (GO:0045123)2.18533795
138actin nucleation (GO:0045010)2.16797198
139neutrophil activation (GO:0042119)2.16537862
140regulation of alpha-beta T cell proliferation (GO:0046640)2.15035920
141granulocyte activation (GO:0036230)2.14736611
142regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.13156866
143valine metabolic process (GO:0006573)2.12030763
144activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.11596601
145interferon-gamma-mediated signaling pathway (GO:0060333)2.11524869
146positive regulation of antigen processing and presentation (GO:0002579)2.11522596
147positive regulation of tolerance induction (GO:0002645)2.10805651
148negative regulation of phagocytosis (GO:0050765)2.10598148
149positive regulation of nuclease activity (GO:0032075)2.10273684
150regulation of hypersensitivity (GO:0002883)2.09578771

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.24108882
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.94980874
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.72047176
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.34276348
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.31399832
6BP1_19119308_ChIP-ChIP_Hs578T_Human2.61169288
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.53595903
8STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.44327021
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.42534289
10* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.38854120
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.37167388
12IRF8_21731497_ChIP-ChIP_J774_Mouse2.36652591
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.34186924
14IRF8_27001747_Chip-Seq_BMDM_Mouse2.32015648
15MYC_22102868_ChIP-Seq_BL_Human2.30934718
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.26905435
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.19566415
18GATA1_22025678_ChIP-Seq_K562_Human2.19441269
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.19086027
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.18505195
21* MAF_26560356_Chip-Seq_TH1_Human2.15881781
22RUNX_20019798_ChIP-Seq_JUKART_Human2.15146140
23MYB_26560356_Chip-Seq_TH2_Human2.13654741
24* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.07979728
25RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.06656268
26VDR_21846776_ChIP-Seq_THP-1_Human2.05986326
27BRD4_27068464_Chip-Seq_AML-cells_Mouse2.04223162
28TCF7_22412390_ChIP-Seq_EML_Mouse1.93272664
29* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.90833855
30STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.90143185
31PPARA_22158963_ChIP-Seq_LIVER_Mouse1.88383685
32PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.84136746
33MYB_26560356_Chip-Seq_TH1_Human1.82060034
34UTX_26944678_Chip-Seq_JUKART_Human1.81997321
35TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.81066428
36VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.79841268
37RXR_22158963_ChIP-Seq_LIVER_Mouse1.78967493
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.78407268
39SCL_19346495_ChIP-Seq_HPC-7_Human1.78052327
40VDR_24763502_ChIP-Seq_THP-1_Human1.76479411
41KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.69799177
42NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.68246529
43CLOCK_20551151_ChIP-Seq_293T_Human1.68174430
44LXR_22158963_ChIP-Seq_LIVER_Mouse1.68129339
45FOXO3_23340844_ChIP-Seq_DLD1_Human1.61663583
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.60455696
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.59126001
48KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.58565114
49KDM2B_26808549_Chip-Seq_DND41_Human1.57965703
50KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.56264761
51E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.55574713
52* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.55220477
53RUNX1_22412390_ChIP-Seq_EML_Mouse1.54038035
54GATA1_19941826_ChIP-Seq_K562_Human1.53459160
55Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.51747051
56* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.49951996
57KDM2B_26808549_Chip-Seq_SUP-B15_Human1.48394214
58GATA3_27048872_Chip-Seq_THYMUS_Human1.46321831
59NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.41705996
60TRIM28_21343339_ChIP-Seq_HEK293_Human1.40232508
61SPI1_23127762_ChIP-Seq_K562_Human1.37460947
62RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.36418047
63TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.35788977
64RARG_19884340_ChIP-ChIP_MEFs_Mouse1.31626349
65GATA2_21666600_ChIP-Seq_HMVEC_Human1.31253377
66SPI1_23547873_ChIP-Seq_NB4_Human1.28786129
67PU_27001747_Chip-Seq_BMDM_Mouse1.27393968
68STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26470498
69KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.25577994
70ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.25327211
71* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24558577
72GATA2_22383799_ChIP-Seq_G1ME_Mouse1.24273944
73GATA2_19941826_ChIP-Seq_K562_Human1.22047984
74MAF_26560356_Chip-Seq_TH2_Human1.21516285
75* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20858833
76CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.20837784
77TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20484204
78SOX2_27498859_Chip-Seq_STOMACH_Mouse1.19574159
79FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.19157614
80RACK7_27058665_Chip-Seq_MCF-7_Human1.17929544
81* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17838005
82GATA1_19941827_ChIP-Seq_MEL_Mouse1.16424534
83* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16389925
84MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.16192419
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12851167
86RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.12172432
87NCOR1_26117541_ChIP-Seq_K562_Human1.11919073
88SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.11663383
89GATA6_25053715_ChIP-Seq_YYC3_Human1.11142766
90VDR_24787735_ChIP-Seq_THP-1_Human1.05991019
91THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.05763698
92PPAR_26484153_Chip-Seq_NCI-H1993_Human1.05600213
93LXR_22292898_ChIP-Seq_THP-1_Human1.05436032
94P63_26484246_Chip-Seq_KERATINOCYTES_Human1.04942764
95SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.04233920
96* TBX20_22328084_ChIP-Seq_HEART_Mouse1.04068775
97* TBX20_22080862_ChIP-Seq_HEART_Mouse1.04068775
98SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.04054631
99SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.04054631
100KDM2B_26808549_Chip-Seq_JURKAT_Human1.03995446
101* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03908193
102ZNF263_19887448_ChIP-Seq_K562_Human1.03405710
103PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02167581
104FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.01831232
105* ATF3_27146783_Chip-Seq_COLON_Human1.01688878
106NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.01296703
107PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00004822
108ESR2_21235772_ChIP-Seq_MCF-7_Human0.99822164
109P300_27058665_Chip-Seq_ZR-75-30cells_Human0.99435288
110SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.97462979
111* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.96532206
112LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.95002676
113* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93997688
114* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93134937
115PU.1_20513432_ChIP-Seq_Bcells_Mouse0.92233761
116* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90738793
117* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88622005
118TFEB_21752829_ChIP-Seq_HELA_Human0.88025829

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003300_gastrointestinal_ulcer3.36895464
2MP0000685_abnormal_immune_system2.52288306
3MP0003303_peritoneal_inflammation2.45173665
4MP0001835_abnormal_antigen_presentation2.34403927
5MP0003436_decreased_susceptibility_to2.32296133
6MP0001790_abnormal_immune_system2.25053672
7MP0005387_immune_system_phenotype2.25053672
8MP0003705_abnormal_hypodermis_morpholog2.18398673
9MP0002166_altered_tumor_susceptibility2.15692449
10MP0004947_skin_inflammation2.04388533
11MP0001800_abnormal_humoral_immune2.03811775
12MP0002877_abnormal_melanocyte_morpholog2.03535327
13MP0005451_abnormal_body_composition2.02018161
14MP0010234_abnormal_vibrissa_follicle1.98041226
15MP0005000_abnormal_immune_tolerance1.97141644
16MP0005671_abnormal_response_to1.94836519
17MP0003763_abnormal_thymus_physiology1.91639365
18MP0002138_abnormal_hepatobiliary_system1.88314646
19MP0009785_altered_susceptibility_to1.81845004
20MP0002452_abnormal_antigen_presenting1.77639020
21MP0010352_gastrointestinal_tract_polyps1.76221711
22MP0005025_abnormal_response_to1.74053006
23MP0006054_spinal_hemorrhage1.73411973
24MP0002723_abnormal_immune_serum1.72129546
25MP0003566_abnormal_cell_adhesion1.69783992
26MP0010155_abnormal_intestine_physiology1.66074001
27MP0002420_abnormal_adaptive_immunity1.65476207
28MP0001819_abnormal_immune_cell1.64042915
29MP0003724_increased_susceptibility_to1.62931890
30MP0006082_CNS_inflammation1.59932619
31MP0002419_abnormal_innate_immunity1.59517571
32MP0002006_tumorigenesis1.53358836
33MP0008260_abnormal_autophagy1.52137957
34MP0005076_abnormal_cell_differentiation1.51755594
35MP0002405_respiratory_system_inflammati1.50233598
36MP0003453_abnormal_keratinocyte_physiol1.48982834
37MP0004510_myositis1.48979612
38MP0002398_abnormal_bone_marrow1.46112783
39MP0002148_abnormal_hypersensitivity_rea1.43953080
40MP0001845_abnormal_inflammatory_respons1.42549874
41MP0001533_abnormal_skeleton_physiology1.40053858
42MP0003191_abnormal_cellular_cholesterol1.38800517
43MP0003656_abnormal_erythrocyte_physiolo1.38524694
44MP0005058_abnormal_lysosome_morphology1.38310630
45MP0005464_abnormal_platelet_physiology1.36382371
46MP0000716_abnormal_immune_system1.34758981
47MP0002933_joint_inflammation1.34597669
48MP0009278_abnormal_bone_marrow1.34082400
49MP0004185_abnormal_adipocyte_glucose1.32391690
50MP0003172_abnormal_lysosome_physiology1.29805597
51MP0001853_heart_inflammation1.25903356
52MP0003866_abnormal_defecation1.24301177
53MP0002060_abnormal_skin_morphology1.22229380
54MP0005275_abnormal_skin_tensile1.20364961
55MP0001873_stomach_inflammation1.19900152
56MP0009333_abnormal_splenocyte_physiolog1.19790226
57MP0003075_altered_response_to1.19639371
58MP0000465_gastrointestinal_hemorrhage1.19076212
59MP0002722_abnormal_immune_system1.18532911
60MP0001545_abnormal_hematopoietic_system1.17610099
61MP0005397_hematopoietic_system_phenotyp1.17610099
62MP0003183_abnormal_peptide_metabolism1.16917097
63MP0000689_abnormal_spleen_morphology1.16369923
64MP0005360_urolithiasis1.15187329
65MP0005166_decreased_susceptibility_to1.15108788
66MP0002429_abnormal_blood_cell1.14276958
67MP0003252_abnormal_bile_duct1.14031797
68MP0005023_abnormal_wound_healing1.13269046
69MP0008469_abnormal_protein_level1.10271726
70MP0003448_altered_tumor_morphology1.09571020
71MP0004883_abnormal_blood_vessel1.08822590
72MP0003045_fibrosis1.08633158
73MP0002998_abnormal_bone_remodeling1.08567808
74MP0005164_abnormal_response_to1.07871741
75MP0009840_abnormal_foam_cell1.07757874
76MP0004381_abnormal_hair_follicle1.07346871
77MP0009643_abnormal_urine_homeostasis1.06678084
78MP0000858_altered_metastatic_potential1.06436691
79MP0001216_abnormal_epidermal_layer1.05147221
80MP0002796_impaired_skin_barrier1.04552521
81MP0008438_abnormal_cutaneous_collagen1.03828271
82MP0000609_abnormal_liver_physiology1.02980465
83MP0002139_abnormal_hepatobiliary_system1.00515868
84MP0000703_abnormal_thymus_morphology0.99253738
85MP0005666_abnormal_adipose_tissue0.98540054
86MP0009764_decreased_sensitivity_to0.96083842
87MP0005310_abnormal_salivary_gland0.96065850
88MP0003828_pulmonary_edema0.95783574
89MP0010678_abnormal_skin_adnexa0.94708793
90MP0008961_abnormal_basal_metabolism0.93248033
91MP0002396_abnormal_hematopoietic_system0.93196228
92MP0008004_abnormal_stomach_pH0.91776227
93MP0001851_eye_inflammation0.91685614
94MP0000249_abnormal_blood_vessel0.91534405
95MP0004808_abnormal_hematopoietic_stem0.91351262
96MP0000343_altered_response_to0.91324259
97MP0002136_abnormal_kidney_physiology0.90598611
98MP0002254_reproductive_system_inflammat0.90249731
99MP0000383_abnormal_hair_follicle0.89582258
100MP0001879_abnormal_lymphatic_vessel0.87943010
101MP0001666_abnormal_nutrient_absorption0.85196754
102MP0001958_emphysema0.84174704
103MP0000604_amyloidosis0.83608434
104MP0000490_abnormal_crypts_of0.82483580
105MP0003091_abnormal_cell_migration0.82238267
106MP0005409_darkened_coat_color0.81646518
107MP0009931_abnormal_skin_appearance0.81523242
108MP0002009_preneoplasia0.80271878
109MP0009763_increased_sensitivity_to0.79348238
110MP0000377_abnormal_hair_follicle0.79125803
111MP0004264_abnormal_extraembryonic_tissu0.78950943
112MP0003795_abnormal_bone_structure0.78851856
113MP0005375_adipose_tissue_phenotype0.78348758
114MP0001191_abnormal_skin_condition0.78097400
115MP0005365_abnormal_bile_salt0.78011269
116MP0002098_abnormal_vibrissa_morphology0.77617674
117MP0003195_calcinosis0.75098595
118MP0003279_aneurysm0.74933122
119MP0003221_abnormal_cardiomyocyte_apopto0.74304261
120MP0003690_abnormal_glial_cell0.71986775
121MP0009115_abnormal_fat_cell0.71029764
122MP0001663_abnormal_digestive_system0.70634526
123MP0001348_abnormal_lacrimal_gland0.69857496

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.66251306
2Hematochezia (HP:0002573)3.29289771
3Spontaneous hematomas (HP:0007420)3.26249735
4T lymphocytopenia (HP:0005403)3.21311974
5Autoimmune thrombocytopenia (HP:0001973)3.18655420
6Abnormality of T cell number (HP:0011839)3.15178771
7Abnormality of the nasal mucosa (HP:0000433)2.97440625
8Nasal polyposis (HP:0100582)2.94167398
9Pustule (HP:0200039)2.94020900
10Chronic otitis media (HP:0000389)2.93658508
11Myocardial infarction (HP:0001658)2.88593236
12Recurrent viral infections (HP:0004429)2.86973162
13Recurrent abscess formation (HP:0002722)2.81444218
14Recurrent bronchitis (HP:0002837)2.77992486
15Abnormality of glycolipid metabolism (HP:0010969)2.77218137
16Abnormality of liposaccharide metabolism (HP:0010968)2.77218137
17Abnormality of glycosphingolipid metabolism (HP:0004343)2.77218137
18Polycythemia (HP:0001901)2.68020563
19Recurrent fungal infections (HP:0002841)2.67520330
20Inflammation of the large intestine (HP:0002037)2.67402516
21Obstructive lung disease (HP:0006536)2.66906640
22Chronic obstructive pulmonary disease (HP:0006510)2.66906640
23Agammaglobulinemia (HP:0004432)2.65232658
24Myositis (HP:0100614)2.63127336
25Pulmonary infiltrates (HP:0002113)2.61926207
26Recurrent bacterial skin infections (HP:0005406)2.61173381
27Increased IgE level (HP:0003212)2.60476239
28Interstitial pulmonary disease (HP:0006530)2.59611008
29Gastrointestinal inflammation (HP:0004386)2.59483770
30Elevated erythrocyte sedimentation rate (HP:0003565)2.59216748
31Recurrent cutaneous fungal infections (HP:0011370)2.55668253
32Chronic mucocutaneous candidiasis (HP:0002728)2.55668253
33Colitis (HP:0002583)2.53017945
34Abnormality of T cells (HP:0002843)2.50109517
35Cellulitis (HP:0100658)2.44177860
36Recurrent gram-negative bacterial infections (HP:0005420)2.41358064
37IgM deficiency (HP:0002850)2.37751263
38Osteolytic defects of the hand bones (HP:0009699)2.37502138
39Osteolytic defects of the phalanges of the hand (HP:0009771)2.37502138
40Abnormality of the fingertips (HP:0001211)2.36383818
41Papilloma (HP:0012740)2.35016301
42Verrucae (HP:0200043)2.35016301
43Abnormal delayed hypersensitivity skin test (HP:0002963)2.34844048
44Vasculitis (HP:0002633)2.32946111
45Keratoconjunctivitis sicca (HP:0001097)2.31434689
46Right ventricular cardiomyopathy (HP:0011663)2.27564356
47Urinary glycosaminoglycan excretion (HP:0003541)2.26140623
48Mucopolysacchariduria (HP:0008155)2.26140623
49Fatigue (HP:0012378)2.24535336
50Stomatitis (HP:0010280)2.23896772
51Malnutrition (HP:0004395)2.22493037
52Dysostosis multiplex (HP:0000943)2.21760600
53Chronic diarrhea (HP:0002028)2.19849076
54Gingival bleeding (HP:0000225)2.18970374
55Encephalitis (HP:0002383)2.18842648
56Arterial thrombosis (HP:0004420)2.17132875
57Systemic lupus erythematosus (HP:0002725)2.16623289
58Abnormality of T cell physiology (HP:0011840)2.14411518
59Orchitis (HP:0100796)2.12603885
60IgA deficiency (HP:0002720)2.10210634
61Abnormality of the peritoneum (HP:0002585)2.09181856
62Abnormal platelet volume (HP:0011876)2.05895532
63Autoimmune hemolytic anemia (HP:0001890)2.05057403
64Meningitis (HP:0001287)2.04531084
65Gastrointestinal stroma tumor (HP:0100723)2.03839861
66Viral hepatitis (HP:0006562)2.03669437
67Abnormality of mucopolysaccharide metabolism (HP:0011020)2.02738774
68Abnormality of polysaccharide metabolism (HP:0011012)2.02738774
69Abnormality of glycosaminoglycan metabolism (HP:0004371)2.02738774
70Cerebral aneurysm (HP:0004944)2.01721890
71Emphysema (HP:0002097)2.01675789
72Keratoconjunctivitis (HP:0001096)1.99377493
73Increased IgM level (HP:0003496)1.99005482
74Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.98895276
75Loss of speech (HP:0002371)1.98836957
76Vacuolated lymphocytes (HP:0001922)1.98248730
77Abnormality of macrophages (HP:0004311)1.97083682
78Hypergammaglobulinemia (HP:0010702)1.95952854
79Impaired platelet aggregation (HP:0003540)1.95708014
80Abnormal platelet function (HP:0011869)1.95708014
81Pulmonary embolism (HP:0002204)1.95674064
82Urticaria (HP:0001025)1.95592430
83Gastrointestinal infarctions (HP:0005244)1.95514956
84Esophageal varix (HP:0002040)1.95162253
85Thin bony cortex (HP:0002753)1.92163810
86Recurrent skin infections (HP:0001581)1.90874363
87Recurrent sinusitis (HP:0011108)1.90355318
88Thick nail (HP:0001805)1.87396792
89Hypoglycemic coma (HP:0001325)1.86973227
90Persistence of primary teeth (HP:0006335)1.86561137
91Gangrene (HP:0100758)1.85862055
92Amyloidosis (HP:0011034)1.85555224
93Osteomyelitis (HP:0002754)1.85038806
94Skin ulcer (HP:0200042)1.83515547
95Ulnar bowing (HP:0003031)1.82056727
96Increased mean platelet volume (HP:0011877)1.82024080
97Glomerulopathy (HP:0100820)1.81902594
98Rectal prolapse (HP:0002035)1.81849802
99Vertebral compression fractures (HP:0002953)1.81781306
100Epistaxis (HP:0000421)1.81683151
101Mediastinal lymphadenopathy (HP:0100721)1.81445779
102Microcytic anemia (HP:0001935)1.81077764
103Deep venous thrombosis (HP:0002625)1.80684729
104Aortic aneurysm (HP:0004942)1.80607184
105Sepsis (HP:0100806)1.80517537
106Spondylolisthesis (HP:0003302)1.80470120
107Petechiae (HP:0000967)1.80468894
108Lymphopenia (HP:0001888)1.79997765
109Conjunctival hamartoma (HP:0100780)1.79911585
110Recurrent pneumonia (HP:0006532)1.79666599
111Increased density of long bones (HP:0006392)1.79339961
112Recurrent lower respiratory tract infections (HP:0002783)1.79298634
113Skin rash (HP:0000988)1.78414716
114Abnormal foot bone ossification (HP:0010675)1.78408412
115Hypochromic anemia (HP:0001931)1.78183729
116Abnormality of the common coagulation pathway (HP:0010990)1.77611306
117Purpura (HP:0000979)1.76167860
118Arthralgia (HP:0002829)1.75793374
119Periodontitis (HP:0000704)1.75560418
120Abnormality of cells of the lymphoid lineage (HP:0012140)1.74891823
121Poikilocytosis (HP:0004447)1.74700161
122Xerostomia (HP:0000217)1.74636054
123Gingivitis (HP:0000230)1.74060688
124Xanthomatosis (HP:0000991)1.74037864
125Acrocyanosis (HP:0001063)1.73945920
126Milia (HP:0001056)1.73620467
127Dilatation of the ascending aorta (HP:0005111)1.73619534
128Prolonged bleeding time (HP:0003010)1.73301573
129Premature loss of primary teeth (HP:0006323)1.71508897
130Subacute progressive viral hepatitis (HP:0006572)1.71399884
131Ventricular tachycardia (HP:0004756)1.70554773
132Peritonitis (HP:0002586)1.70408810
133Hyporeflexia of lower limbs (HP:0002600)1.68562288
134Chest pain (HP:0100749)1.68291014
135Hemoptysis (HP:0002105)1.67332007
136Eosinophilia (HP:0001880)1.67244655
137Mitral valve prolapse (HP:0001634)1.64899754
138Retrobulbar optic neuritis (HP:0100654)1.63813334
139Optic neuritis (HP:0100653)1.63813334
140Restrictive lung disease (HP:0002091)1.63512625

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.97489044
2PRPF4B3.75242792
3TRIB33.58635111
4MAP4K13.23670302
5ERN12.77699699
6MAP3K132.53985913
7STK102.39021366
8PKN22.35646323
9TYK22.18206550
10EPHB12.10900115
11FGFR42.00369324
12MAP3K101.94436801
13LRRK21.92611163
14TAOK31.89750105
15TBK11.88695495
16JAK31.88435378
17ITK1.86318757
18BLK1.83637863
19MST41.78896498
20JAK11.73780404
21ZAP701.69688897
22BMPR21.63928967
23PTK61.62022314
24FGFR31.61859115
25TTN1.60082645
26TGFBR21.56404129
27CSK1.54219797
28MAP3K141.52487412
29TRPM71.52061922
30EEF2K1.50297011
31FRK1.48692540
32TXK1.48607142
33GRK61.46654981
34IKBKE1.43819444
35CDK121.43673435
36MAP3K31.36356826
37FES1.34857373
38SMG11.30806714
39RIPK11.26609483
40MAP2K31.24886983
41BTK1.20617470
42IRAK31.20406305
43CDC42BPA1.19449848
44RPS6KA41.18409392
45FGR1.16776146
46SIK31.16738902
47JAK21.14443092
48TAOK21.11735942
49DMPK1.11541419
50TEC1.10631624
51KSR21.08184024
52PRKCH1.07378474
53NEK91.04608197
54HIPK21.03920780
55NLK0.99779281
56KDR0.98518740
57IKBKB0.98108540
58SIK10.96042183
59CDK60.94522944
60SYK0.94040259
61EPHA30.93402172
62PIM10.92632043
63PDPK10.91705530
64HCK0.91195832
65STK40.89817992
66STK30.89645700
67LCK0.89240781
68IRAK40.87777364
69MATK0.87510770
70MARK30.85864859
71CHUK0.85787883
72BMX0.80986959
73MOS0.80571803
74IRAK20.80012483
75PRKCQ0.79904982
76MAPK70.79496512
77STK240.78229619
78MAP3K10.78065876
79PDGFRA0.78002019
80MAPK120.74300862
81MST1R0.73504610
82SCYL20.73444454
83DYRK1B0.72986776
84ARAF0.72741547
85KIT0.72411666
86PDGFRB0.72262647
87FLT30.70730754
88MELK0.69741078
89NME20.68760536
90MAP3K70.68373132
91CSF1R0.64961247
92DDR20.64898242
93MAPK110.64008687
94MAP3K60.63286117
95MARK20.62474404
96CLK10.61156488
97PIK3CG0.59241665
98MAP3K20.59183956
99PRKD10.58868423
100MAP2K20.57958875
101MAPKAPK30.56720490
102PTK20.56549185
103LATS10.56381348
104NUAK10.56097481
105FGFR20.55773030
106TNK20.55512481
107ICK0.55197385
108CAMK1D0.54783902
109EGFR0.51359736
110MAP3K110.50253159
111PRKD20.48549471
112MAP3K80.47623983
113MAPKAPK20.47591230
114CDK40.47571795
115RET0.47418916
116MAPK40.47326269
117LYN0.46012710
118INSRR0.44245694
119RPS6KL10.44041620
120RPS6KC10.44041620
121GSK3A0.43446644
122WNK40.42946649
123MAP3K50.42784342
124PRKG20.42553710
125YES10.41864121
126TAOK10.41015303
127IRAK10.40543629
128PDK10.39466580
129SIK20.38636687
130ILK0.38515998
131ABL10.37892236
132SGK30.37655153

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.52469623
2Leishmaniasis_Homo sapiens_hsa051402.23236175
3Osteoclast differentiation_Homo sapiens_hsa043802.07845948
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.04408174
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.01202523
6B cell receptor signaling pathway_Homo sapiens_hsa046621.96791426
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.86377230
8Staphylococcus aureus infection_Homo sapiens_hsa051501.82409451
9Antigen processing and presentation_Homo sapiens_hsa046121.81473521
10Measles_Homo sapiens_hsa051621.79809605
11Toxoplasmosis_Homo sapiens_hsa051451.77726009
12Caffeine metabolism_Homo sapiens_hsa002321.77193856
13Type I diabetes mellitus_Homo sapiens_hsa049401.71473133
14Leukocyte transendothelial migration_Homo sapiens_hsa046701.68745719
15T cell receptor signaling pathway_Homo sapiens_hsa046601.63962907
16Hematopoietic cell lineage_Homo sapiens_hsa046401.56193534
17Toll-like receptor signaling pathway_Homo sapiens_hsa046201.51817859
18Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.45422063
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.44256835
20Chronic myeloid leukemia_Homo sapiens_hsa052201.39035423
21Viral myocarditis_Homo sapiens_hsa054161.33150877
22TNF signaling pathway_Homo sapiens_hsa046681.31709986
23Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.30483004
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.29955252
25Small cell lung cancer_Homo sapiens_hsa052221.29204644
26Rheumatoid arthritis_Homo sapiens_hsa053231.26374416
27Insulin resistance_Homo sapiens_hsa049311.24468346
28Malaria_Homo sapiens_hsa051441.22914584
29Tuberculosis_Homo sapiens_hsa051521.22696320
30Apoptosis_Homo sapiens_hsa042101.20971150
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.20858303
32Acute myeloid leukemia_Homo sapiens_hsa052211.20186903
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.19862819
34Pertussis_Homo sapiens_hsa051331.19842610
35Pancreatic cancer_Homo sapiens_hsa052121.19624426
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.18064788
37Nitrogen metabolism_Homo sapiens_hsa009101.17004624
38Chemokine signaling pathway_Homo sapiens_hsa040621.12336903
39Hepatitis B_Homo sapiens_hsa051611.12019137
40NOD-like receptor signaling pathway_Homo sapiens_hsa046211.11908124
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.10528308
42Influenza A_Homo sapiens_hsa051641.08259844
43Herpes simplex infection_Homo sapiens_hsa051681.08223882
44Phagosome_Homo sapiens_hsa041451.08106801
45Legionellosis_Homo sapiens_hsa051341.07341992
46Glycosaminoglycan degradation_Homo sapiens_hsa005311.07290676
47Graft-versus-host disease_Homo sapiens_hsa053321.06783727
48Platelet activation_Homo sapiens_hsa046111.06773452
49Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.06067447
50Lysosome_Homo sapiens_hsa041421.05245273
51Shigellosis_Homo sapiens_hsa051311.03636042
52Hepatitis C_Homo sapiens_hsa051601.02321881
53African trypanosomiasis_Homo sapiens_hsa051431.01601795
54Adipocytokine signaling pathway_Homo sapiens_hsa049201.01258288
55Allograft rejection_Homo sapiens_hsa053301.00326036
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99681096
57Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.98497853
58Adherens junction_Homo sapiens_hsa045200.96129547
59Focal adhesion_Homo sapiens_hsa045100.94076862
60Proteoglycans in cancer_Homo sapiens_hsa052050.90945522
61Amoebiasis_Homo sapiens_hsa051460.90575224
62Prolactin signaling pathway_Homo sapiens_hsa049170.90563647
63Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.89964832
64ABC transporters_Homo sapiens_hsa020100.89369795
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.88638353
66VEGF signaling pathway_Homo sapiens_hsa043700.86873536
67Fatty acid degradation_Homo sapiens_hsa000710.86212094
68Asthma_Homo sapiens_hsa053100.82369573
69Salmonella infection_Homo sapiens_hsa051320.82262441
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.80671841
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.80400692
72Epstein-Barr virus infection_Homo sapiens_hsa051690.76998243
73ECM-receptor interaction_Homo sapiens_hsa045120.76819991
74Viral carcinogenesis_Homo sapiens_hsa052030.76772651
75Lysine degradation_Homo sapiens_hsa003100.75784449
76Complement and coagulation cascades_Homo sapiens_hsa046100.73727713
77Other glycan degradation_Homo sapiens_hsa005110.72529244
78Prostate cancer_Homo sapiens_hsa052150.71372303
79Tryptophan metabolism_Homo sapiens_hsa003800.70806120
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70096708
81Non-small cell lung cancer_Homo sapiens_hsa052230.70089397
82Endometrial cancer_Homo sapiens_hsa052130.69744410
83Carbohydrate digestion and absorption_Homo sapiens_hsa049730.69371934
84GnRH signaling pathway_Homo sapiens_hsa049120.67861835
85Dorso-ventral axis formation_Homo sapiens_hsa043200.67199419
86Autoimmune thyroid disease_Homo sapiens_hsa053200.66472305
87Bladder cancer_Homo sapiens_hsa052190.66204411
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65631231
89HTLV-I infection_Homo sapiens_hsa051660.65420519
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.65127588
91Prion diseases_Homo sapiens_hsa050200.64527855
92PPAR signaling pathway_Homo sapiens_hsa033200.64314542
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62715052
94HIF-1 signaling pathway_Homo sapiens_hsa040660.62154526
95Sulfur metabolism_Homo sapiens_hsa009200.61961334
96Notch signaling pathway_Homo sapiens_hsa043300.60028456
97Endocytosis_Homo sapiens_hsa041440.59535199
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.59327300
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59321386
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.59058378
101FoxO signaling pathway_Homo sapiens_hsa040680.58712282
102Thyroid cancer_Homo sapiens_hsa052160.58555865
103Glioma_Homo sapiens_hsa052140.57839516
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.57101777
105Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56047341
106Systemic lupus erythematosus_Homo sapiens_hsa053220.55904966
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.53036742
108Renal cell carcinoma_Homo sapiens_hsa052110.52964102
109mTOR signaling pathway_Homo sapiens_hsa041500.52470225
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51598160
111Selenocompound metabolism_Homo sapiens_hsa004500.49216136
112Fat digestion and absorption_Homo sapiens_hsa049750.49092845
113Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49078720
114ErbB signaling pathway_Homo sapiens_hsa040120.48198577
115Insulin signaling pathway_Homo sapiens_hsa049100.47665416
116Starch and sucrose metabolism_Homo sapiens_hsa005000.47428942
117Choline metabolism in cancer_Homo sapiens_hsa052310.46910863
118MicroRNAs in cancer_Homo sapiens_hsa052060.46774095
119Inositol phosphate metabolism_Homo sapiens_hsa005620.46378532
120Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45950412
121Colorectal cancer_Homo sapiens_hsa052100.45391651
122Estrogen signaling pathway_Homo sapiens_hsa049150.43158487
123MAPK signaling pathway_Homo sapiens_hsa040100.42036739
124Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41840670
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.41776178
126Protein digestion and absorption_Homo sapiens_hsa049740.39640529

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