MB21D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of interleukin-12 production (GO:0032695)4.17212378
2neutrophil activation involved in immune response (GO:0002283)3.97409007
3response to peptidoglycan (GO:0032494)3.94591100
4regulation of vitamin D biosynthetic process (GO:0060556)3.79488019
5regulation of chronic inflammatory response (GO:0002676)3.75076641
6immunoglobulin mediated immune response (GO:0016064)3.64661523
7regulation of RIG-I signaling pathway (GO:0039535)3.56766172
8DNA deamination (GO:0045006)3.52155966
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.49746414
10positive regulation by symbiont of host defense response (GO:0052509)3.47980210
11modulation by symbiont of host defense response (GO:0052031)3.47980210
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.47980210
13modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.47980210
14positive regulation by organism of defense response of other organism involved in symbiotic interact3.47980210
15modulation by symbiont of host immune response (GO:0052553)3.47980210
16regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.47146252
17positive regulation of interleukin-12 production (GO:0032735)3.45942118
18telomere maintenance via semi-conservative replication (GO:0032201)3.45723611
19type I interferon signaling pathway (GO:0060337)3.45563745
20cellular response to type I interferon (GO:0071357)3.45563745
21response to type I interferon (GO:0034340)3.42950397
22telomere maintenance via recombination (GO:0000722)3.41717947
23positive regulation of interferon-alpha production (GO:0032727)3.41670865
24regulation of interleukin-12 production (GO:0032655)3.40655111
25cellular response to interferon-beta (GO:0035458)3.36249324
26tryptophan catabolic process (GO:0006569)3.33821071
27indole-containing compound catabolic process (GO:0042436)3.33821071
28indolalkylamine catabolic process (GO:0046218)3.33821071
29positive regulation of T-helper 1 type immune response (GO:0002827)3.32841639
30kynurenine metabolic process (GO:0070189)3.32216241
31negative regulation of T cell mediated immunity (GO:0002710)3.25404009
32negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.23271774
33negative regulation of cell killing (GO:0031342)3.23271774
34regulation of interferon-alpha production (GO:0032647)3.22429297
35response to muramyl dipeptide (GO:0032495)3.21499684
36T-helper 1 type immune response (GO:0042088)3.21495918
37regulation of interleukin-12 biosynthetic process (GO:0045075)3.17390713
38positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.15633586
39neutrophil activation (GO:0042119)3.15347176
40macrophage activation involved in immune response (GO:0002281)3.12582057
41regulation of T-helper 1 type immune response (GO:0002825)3.11925162
42mitotic recombination (GO:0006312)3.08586547
43defense response to protozoan (GO:0042832)3.07401958
44regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.05633645
45respiratory burst (GO:0045730)3.04962977
46tolerance induction (GO:0002507)3.04063710
47response to interferon-alpha (GO:0035455)3.03083556
48positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.02690970
49regulation of interleukin-1 beta secretion (GO:0050706)3.02298538
50regulation of T cell mediated cytotoxicity (GO:0001914)3.01670840
51regulation of MHC class I biosynthetic process (GO:0045343)3.00277388
52superoxide anion generation (GO:0042554)2.99759320
53positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.98908130
54tryptophan metabolic process (GO:0006568)2.98832194
55regulation of dendritic cell antigen processing and presentation (GO:0002604)2.98353818
56positive regulation of heat generation (GO:0031652)2.97980997
57granulocyte activation (GO:0036230)2.97164461
58positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.96759582
59negative regulation of viral genome replication (GO:0045071)2.96704997
60DNA strand elongation involved in DNA replication (GO:0006271)2.95712168
61regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.94693606
62positive regulation of gamma-delta T cell activation (GO:0046645)2.94468642
63* regulation of defense response to virus by host (GO:0050691)2.93410737
64mast cell activation (GO:0045576)2.93368682
65regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.92731338
66regulation of B cell receptor signaling pathway (GO:0050855)2.91995171
67natural killer cell activation involved in immune response (GO:0002323)2.91654077
68negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.91521985
69response to interferon-beta (GO:0035456)2.90693253
70positive regulation of interleukin-1 secretion (GO:0050716)2.90626994
71myeloid dendritic cell activation (GO:0001773)2.90321355
72positive regulation of NF-kappaB import into nucleus (GO:0042346)2.89745939
73regulation of T-helper cell differentiation (GO:0045622)2.88186541
74positive regulation of T cell mediated cytotoxicity (GO:0001916)2.87973615
75DNA strand elongation (GO:0022616)2.86263803
76regulation of gamma-delta T cell activation (GO:0046643)2.85937744
77positive regulation of interferon-gamma production (GO:0032729)2.83907806
78regulation of inflammatory response to antigenic stimulus (GO:0002861)2.83672221
79positive regulation of natural killer cell differentiation (GO:0032825)2.83431437
80regulation of regulatory T cell differentiation (GO:0045589)2.83085379
81regulation of immunoglobulin secretion (GO:0051023)2.82894772
82B cell mediated immunity (GO:0019724)2.82847696
83positive regulation of toll-like receptor signaling pathway (GO:0034123)2.82758108
84regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.82454236
85cellular response to interleukin-15 (GO:0071350)2.81153610
86response to protozoan (GO:0001562)2.80339860
87negative regulation of DNA-dependent DNA replication (GO:2000104)2.80009397
88cellular response to interferon-gamma (GO:0071346)2.79626772
89neutrophil mediated immunity (GO:0002446)2.78942295
90NIK/NF-kappaB signaling (GO:0038061)2.78625778
91kinetochore organization (GO:0051383)2.78533953
92interferon-gamma production (GO:0032609)2.77715447
93positive regulation of antigen processing and presentation (GO:0002579)2.77250738
94regulation of interferon-beta production (GO:0032648)2.76988376
95antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.76467032
96antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.76467032
97T cell migration (GO:0072678)2.75922364
98regulation of interferon-beta biosynthetic process (GO:0045357)2.75305310
99positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.75037481
100lipopolysaccharide-mediated signaling pathway (GO:0031663)2.74978993
101positive regulation of type 2 immune response (GO:0002830)2.74595940
102lymphocyte chemotaxis (GO:0048247)2.74433504
103positive regulation of T-helper cell differentiation (GO:0045624)2.73269831
104DNA replication initiation (GO:0006270)2.73182010
105positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.72846000
106regulation of vitamin metabolic process (GO:0030656)2.72213415
107response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.70243806
108response to host immune response (GO:0052572)2.70243806
109regulation of antigen processing and presentation (GO:0002577)2.70204137
110antigen processing and presentation of endogenous antigen (GO:0019883)2.65062637
111regulation of T-helper 1 cell differentiation (GO:0045625)2.64985339
112Arp2/3 complex-mediated actin nucleation (GO:0034314)2.64818510
113myeloid cell activation involved in immune response (GO:0002275)2.63674403
114dendritic cell chemotaxis (GO:0002407)2.63246921
115interferon-gamma-mediated signaling pathway (GO:0060333)2.61838184
116regulation of mast cell activation (GO:0033003)2.61290919
117maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.60962562
118telomere maintenance via telomere lengthening (GO:0010833)2.60912230
119positive regulation of interferon-beta production (GO:0032728)2.59747050
120DNA replication checkpoint (GO:0000076)2.59089198
121kinetochore assembly (GO:0051382)2.58822359
122positive regulation of B cell differentiation (GO:0045579)2.57791791
123DNA strand renaturation (GO:0000733)2.56818174
124CENP-A containing nucleosome assembly (GO:0034080)2.54680299
125positive regulation of interleukin-17 production (GO:0032740)2.53522064
126regulation of double-strand break repair via homologous recombination (GO:0010569)2.53025672
127nucleotide-excision repair, DNA gap filling (GO:0006297)2.52547731
128positive regulation of T cell migration (GO:2000406)2.51501987
129negative regulation of growth of symbiont in host (GO:0044130)2.51408940
130negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.51408940
131modulation of growth of symbiont involved in interaction with host (GO:0044144)2.51408940
132regulation of growth of symbiont in host (GO:0044126)2.51408940
133leukocyte aggregation (GO:0070486)2.51140141
134negative regulation of myeloid cell apoptotic process (GO:0033033)2.48723603
135natural killer cell mediated cytotoxicity (GO:0042267)2.48708327
136natural killer cell mediated immunity (GO:0002228)2.48708327
137negative regulation of phagocytosis (GO:0050765)2.48500052
138chromatin remodeling at centromere (GO:0031055)2.46035871
139positive regulation of alpha-beta T cell proliferation (GO:0046641)2.45978843
140* positive regulation of defense response to virus by host (GO:0002230)2.45535180
141leukocyte degranulation (GO:0043299)2.44899412
142positive regulation of interleukin-1 beta secretion (GO:0050718)2.43208678
143germinal center formation (GO:0002467)2.42648893
144positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.42593887
145dendritic cell migration (GO:0036336)2.42266167
146regulation of mast cell degranulation (GO:0043304)2.42239271
147ribosomal small subunit assembly (GO:0000028)2.41771093
148mature B cell differentiation (GO:0002335)2.41378257
149regulation of alpha-beta T cell proliferation (GO:0046640)2.41348301
150production of molecular mediator involved in inflammatory response (GO:0002532)2.41055694
151meiotic chromosome segregation (GO:0045132)2.40532986
152DNA synthesis involved in DNA repair (GO:0000731)2.40310743
153telomere maintenance (GO:0000723)2.40192870
154myeloid dendritic cell differentiation (GO:0043011)2.39549436
155response to host defenses (GO:0052200)2.39081068

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.71569055
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.00687338
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.74290942
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.01012949
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.37760948
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.32840248
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.21626965
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.87172582
9MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.83446202
10IRF8_27001747_Chip-Seq_BMDM_Mouse2.81374458
11SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.79701707
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.50074910
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.49909272
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.47264191
15STAT4_19710469_ChIP-ChIP_TH1__Mouse2.44728692
16SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.44022314
17MYB_21317192_ChIP-Seq_ERMYB_Mouse2.43694982
18STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.35149622
19SCL_19346495_ChIP-Seq_HPC-7_Human2.33753067
20NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.29475259
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.24368743
22* SPI1_23547873_ChIP-Seq_NB4_Human2.21588831
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.20477275
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.05520329
25FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.00216556
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.98130090
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.94094832
28NOTCH1_21737748_ChIP-Seq_TLL_Human1.87267988
29ZNF274_21170338_ChIP-Seq_K562_Hela1.86592013
30MYB_26560356_Chip-Seq_TH2_Human1.79330864
31HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68401417
32KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.68059054
33VDR_24787735_ChIP-Seq_THP-1_Human1.65705824
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65253732
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.65240219
36MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.64010006
37RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.63969575
38E2F1_21310950_ChIP-Seq_MCF-7_Human1.59987883
39SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.59986623
40MYB_26560356_Chip-Seq_TH1_Human1.59891181
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57259487
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.51496857
43ERG_20887958_ChIP-Seq_HPC-7_Mouse1.50813410
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50264830
45FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.45818644
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.45140017
47VDR_23849224_ChIP-Seq_CD4+_Human1.44858835
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.44775847
49Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.44633545
50ELK1_19687146_ChIP-ChIP_HELA_Human1.44090673
51GABP_17652178_ChIP-ChIP_JURKAT_Human1.43657068
52PU_27001747_Chip-Seq_BMDM_Mouse1.41596959
53LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.41293166
54EST1_17652178_ChIP-ChIP_JURKAT_Human1.41108894
55E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.40408394
56GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39946744
57VDR_24763502_ChIP-Seq_THP-1_Human1.39368956
58GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.38896914
59VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.36207895
60PCGF2_27294783_Chip-Seq_ESCs_Mouse1.36164216
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.34045178
62GATA1_22025678_ChIP-Seq_K562_Human1.31361112
63MAF_26560356_Chip-Seq_TH1_Human1.30711012
64RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29252584
65VDR_21846776_ChIP-Seq_THP-1_Human1.29149898
66VDR_22108803_ChIP-Seq_LS180_Human1.25205290
67LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.25099996
68FOXP3_21729870_ChIP-Seq_TREG_Human1.20205931
69EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.18321169
70RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.16079933
71GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16013543
72MYC_18555785_ChIP-Seq_MESCs_Mouse1.15722837
73RUNX_20019798_ChIP-Seq_JUKART_Human1.14952148
74SMRT_27268052_Chip-Seq_Bcells_Human1.11359313
75NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10960578
76EGR1_23403033_ChIP-Seq_LIVER_Mouse1.10661059
77STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.10368288
78TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07771896
79CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06871537
80STAT1_20625510_ChIP-Seq_HELA_Human1.05461361
81NFE2_27457419_Chip-Seq_LIVER_Mouse1.04778172
82HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.03452836
83BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.01916886
84SRF_21415370_ChIP-Seq_HL-1_Mouse1.00909703
85IGF1R_20145208_ChIP-Seq_DFB_Human0.98957364
86SUZ12_27294783_Chip-Seq_NPCs_Mouse0.98937064
87SPI1_23127762_ChIP-Seq_K562_Human0.98068142
88PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97807279
89PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97661223
90PCGF2_27294783_Chip-Seq_NPCs_Mouse0.97587877
91GATA3_26560356_Chip-Seq_TH2_Human0.97431564
92JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97334380
93RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.96613731
94JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94178217
95IRF1_19129219_ChIP-ChIP_H3396_Human0.93957246
96GATA3_26560356_Chip-Seq_TH1_Human0.93449088
97CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.93378534
98NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.92627208
99ER_23166858_ChIP-Seq_MCF-7_Human0.92284323
100EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.92109773
101GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.91440277
102NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.91247637
103MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.90849003
104FOXA1_25329375_ChIP-Seq_VCAP_Human0.90471472
105FOXA1_27270436_Chip-Seq_PROSTATE_Human0.90471472
106CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90230459
107TP53_22573176_ChIP-Seq_HFKS_Human0.89469130
108MAF_26560356_Chip-Seq_TH2_Human0.89081504
109GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88850507
110UTX_26944678_Chip-Seq_JUKART_Human0.87878285
111FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87642314
112EZH2_27294783_Chip-Seq_NPCs_Mouse0.87519064
113PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87181415
114GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.86743092
115CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85955314
116GATA3_27048872_Chip-Seq_THYMUS_Human0.85882385
117GATA3_21878914_ChIP-Seq_MCF-7_Human0.84152132
118MYC_19030024_ChIP-ChIP_MESCs_Mouse0.83906873
119P300_27268052_Chip-Seq_Bcells_Human0.83486829
120TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.83064707
121STAT3_18555785_Chip-Seq_ESCs_Mouse0.82983368
122MYC_18358816_ChIP-ChIP_MESCs_Mouse0.81470341
123CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.81038374
124SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80950336
125SMAD_19615063_ChIP-ChIP_OVARY_Human0.80819217
126PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80534617
127EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.80470460
128DCP1A_22483619_ChIP-Seq_HELA_Human0.80464245
129MYC_18940864_ChIP-ChIP_HL60_Human0.80162282

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.13785995
2MP0009785_altered_susceptibility_to3.20126722
3MP0002148_abnormal_hypersensitivity_rea3.00417020
4MP0002396_abnormal_hematopoietic_system2.86130016
5MP0005671_abnormal_response_to2.85557947
6MP0003436_decreased_susceptibility_to2.84440229
7MP0003724_increased_susceptibility_to2.72608125
8MP0005000_abnormal_immune_tolerance2.66589456
9MP0005025_abnormal_response_to2.62712232
10MP0002419_abnormal_innate_immunity2.58706231
11MP0005174_abnormal_tail_pigmentation2.56427313
12MP0010094_abnormal_chromosome_stability2.47200079
13MP0005387_immune_system_phenotype2.46668092
14MP0001790_abnormal_immune_system2.46668092
15MP0002452_abnormal_antigen_presenting2.43243095
16MP0001800_abnormal_humoral_immune2.41806427
17MP0002723_abnormal_immune_serum2.37313488
18MP0008057_abnormal_DNA_replication2.34848831
19MP0001819_abnormal_immune_cell2.29216184
20MP0002420_abnormal_adaptive_immunity2.27085104
21MP0000685_abnormal_immune_system2.21405128
22MP0003763_abnormal_thymus_physiology2.18008883
23MP0003693_abnormal_embryo_hatching2.07269334
24MP0000015_abnormal_ear_pigmentation2.05754642
25MP0002398_abnormal_bone_marrow1.99551167
26MP0005464_abnormal_platelet_physiology1.98435030
27MP0002006_tumorigenesis1.87582823
28MP0006082_CNS_inflammation1.86430336
29MP0008058_abnormal_DNA_repair1.84584515
30MP0000716_abnormal_immune_system1.82527226
31MP0000490_abnormal_crypts_of1.82018128
32MP0004808_abnormal_hematopoietic_stem1.80493290
33MP0001853_heart_inflammation1.78079904
34MP0009333_abnormal_splenocyte_physiolog1.78076524
35MP0003195_calcinosis1.77682766
36MP0002405_respiratory_system_inflammati1.75183495
37MP0003303_peritoneal_inflammation1.74974344
38MP0001545_abnormal_hematopoietic_system1.73650840
39MP0005397_hematopoietic_system_phenotyp1.73650840
40MP0002166_altered_tumor_susceptibility1.72131148
41MP0003806_abnormal_nucleotide_metabolis1.70352644
42MP0003111_abnormal_nucleus_morphology1.68977284
43MP0005075_abnormal_melanosome_morpholog1.68397026
44MP0010155_abnormal_intestine_physiology1.65135220
45MP0008007_abnormal_cellular_replicative1.62767633
46MP0000569_abnormal_digit_pigmentation1.58522360
47MP0003646_muscle_fatigue1.57603169
48MP0002429_abnormal_blood_cell1.56047006
49MP0000689_abnormal_spleen_morphology1.55846652
50MP0004381_abnormal_hair_follicle1.52117430
51MP0002722_abnormal_immune_system1.50707444
52MP0003077_abnormal_cell_cycle1.47766801
53MP0002138_abnormal_hepatobiliary_system1.47490110
54MP0000465_gastrointestinal_hemorrhage1.47002937
55MP0003300_gastrointestinal_ulcer1.43387523
56MP0001845_abnormal_inflammatory_respons1.42777404
57MP0002095_abnormal_skin_pigmentation1.42128277
58MP0001188_hyperpigmentation1.40371014
59MP0005167_abnormal_blood-brain_barrier1.38361221
60MP0001986_abnormal_taste_sensitivity1.32453614
61MP0001533_abnormal_skeleton_physiology1.29803858
62MP0000858_altered_metastatic_potential1.29462384
63MP0000703_abnormal_thymus_morphology1.28097196
64MP0001873_stomach_inflammation1.24902592
65MP0005310_abnormal_salivary_gland1.22391295
66MP0009278_abnormal_bone_marrow1.22012616
67MP0009764_decreased_sensitivity_to1.21138864
68MP0008469_abnormal_protein_level1.17618334
69MP0003448_altered_tumor_morphology1.17568428
70MP0002332_abnormal_exercise_endurance1.15314962
71MP0010307_abnormal_tumor_latency1.14357869
72MP0006292_abnormal_olfactory_placode1.13329369
73MP0002254_reproductive_system_inflammat1.13320514
74MP0003172_abnormal_lysosome_physiology1.08620564
75MP0002277_abnormal_respiratory_mucosa1.07239405
76MP0002019_abnormal_tumor_incidence1.06229724
77MP0005409_darkened_coat_color1.06186356
78MP0004947_skin_inflammation1.04904847
79MP0003075_altered_response_to1.02549558
80MP0003866_abnormal_defecation1.00363064
81MP0009840_abnormal_foam_cell1.00123609
82MP0005058_abnormal_lysosome_morphology0.99091288
83MP0000372_irregular_coat_pigmentation0.97592461
84MP0004782_abnormal_surfactant_physiolog0.97534772
85MP0003136_yellow_coat_color0.96706910
86MP0000343_altered_response_to0.96027050
87MP0008877_abnormal_DNA_methylation0.95704676
88MP0005084_abnormal_gallbladder_morpholo0.95574828
89MP0001663_abnormal_digestive_system0.95522400
90MP0000371_diluted_coat_color0.94712099
91MP0002163_abnormal_gland_morphology0.94252461
92MP0002693_abnormal_pancreas_physiology0.91370387
93MP0002009_preneoplasia0.89754670
94MP0004510_myositis0.84164391
95MP0001501_abnormal_sleep_pattern0.83516760
96MP0002837_dystrophic_cardiac_calcinosis0.83324771
97MP0005164_abnormal_response_to0.82871426
98MP0003183_abnormal_peptide_metabolism0.82697403
99MP0008932_abnormal_embryonic_tissue0.82436093
100MP0003943_abnormal_hepatobiliary_system0.82259250
101MP0008875_abnormal_xenobiotic_pharmacok0.82243769
102MP0000313_abnormal_cell_death0.81290706
103MP0005451_abnormal_body_composition0.81223896
104MP0001851_eye_inflammation0.80970729
105MP0002132_abnormal_respiratory_system0.78198098
106MP0002075_abnormal_coat/hair_pigmentati0.77567877
107MP0004957_abnormal_blastocyst_morpholog0.77365018
108MP0001186_pigmentation_phenotype0.76474095
109MP0002933_joint_inflammation0.75913295
110MP0002998_abnormal_bone_remodeling0.75260273
111MP0001919_abnormal_reproductive_system0.75026579
112MP0009763_increased_sensitivity_to0.73549753
113MP0003950_abnormal_plasma_membrane0.72994482
114MP0000427_abnormal_hair_cycle0.72075275
115MP0003045_fibrosis0.71727180
116MP0009765_abnormal_xenobiotic_induced0.71711340
117MP0008260_abnormal_autophagy0.71246209
118MP0001542_abnormal_bone_strength0.70882444
119MP0002876_abnormal_thyroid_physiology0.69501432
120MP0001119_abnormal_female_reproductive0.68331523
121MP0003656_abnormal_erythrocyte_physiolo0.66697562
122MP0003718_maternal_effect0.66519767
123MP0005166_decreased_susceptibility_to0.66435217
124MP0003786_premature_aging0.66393138
125MP0000604_amyloidosis0.66388654
126MP0005390_skeleton_phenotype0.66132462
127MP0004883_abnormal_blood_vessel0.65953434
128MP0005266_abnormal_metabolism0.64751831
129MP0003828_pulmonary_edema0.63740817
130MP0001764_abnormal_homeostasis0.63733120
131MP0006054_spinal_hemorrhage0.63437667
132MP0005645_abnormal_hypothalamus_physiol0.60866648
133MP0000249_abnormal_blood_vessel0.58787501
134MP0002136_abnormal_kidney_physiology0.58071853

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.06457562
2Chromsome breakage (HP:0040012)4.75774714
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.73021247
4Recurrent bacterial skin infections (HP:0005406)4.56468624
5Elevated erythrocyte sedimentation rate (HP:0003565)4.18599534
6Eczematoid dermatitis (HP:0000976)4.14743333
7Abnormality of T cell number (HP:0011839)3.60861706
8T lymphocytopenia (HP:0005403)3.58850255
9Mediastinal lymphadenopathy (HP:0100721)3.54930776
10Prostate neoplasm (HP:0100787)3.52406002
11Myositis (HP:0100614)3.50425913
12Obstructive lung disease (HP:0006536)3.46802722
13Chronic obstructive pulmonary disease (HP:0006510)3.46802722
14Recurrent fungal infections (HP:0002841)3.37811066
15Keratoconjunctivitis (HP:0001096)3.33366166
16Recurrent viral infections (HP:0004429)3.28039651
17Abnormality of liposaccharide metabolism (HP:0010968)3.14511566
18Abnormality of glycosphingolipid metabolism (HP:0004343)3.14511566
19Abnormality of glycolipid metabolism (HP:0010969)3.14511566
20Abnormality of the prostate (HP:0008775)3.12099837
21Recurrent skin infections (HP:0001581)3.11017365
22Recurrent cutaneous fungal infections (HP:0011370)3.10303722
23Chronic mucocutaneous candidiasis (HP:0002728)3.10303722
24Abnormality of chromosome stability (HP:0003220)3.08694545
25Recurrent gram-negative bacterial infections (HP:0005420)3.08114160
26IgM deficiency (HP:0002850)3.05768083
27Clubbing of toes (HP:0100760)3.05698639
28Optic neuritis (HP:0100653)3.03620842
29Retrobulbar optic neuritis (HP:0100654)3.03620842
30Abnormal delayed hypersensitivity skin test (HP:0002963)2.95286559
31Thrombocytosis (HP:0001894)2.93232771
32Chronic otitis media (HP:0000389)2.93068950
33Basal ganglia calcification (HP:0002135)2.90999566
34Meningitis (HP:0001287)2.90000815
35Reticulocytopenia (HP:0001896)2.89545171
36Abnormality of macrophages (HP:0004311)2.81879671
37Petechiae (HP:0000967)2.74865154
38Abnormality of T cell physiology (HP:0011840)2.73842971
39Orchitis (HP:0100796)2.73554990
40Autoimmune thrombocytopenia (HP:0001973)2.72930920
41Birth length less than 3rd percentile (HP:0003561)2.72448313
42Aplastic anemia (HP:0001915)2.72213733
43Increased neuronal autofluorescent lipopigment (HP:0002074)2.71855431
44Congenital stationary night blindness (HP:0007642)2.65899263
45Abnormality of the preputium (HP:0100587)2.65861556
46Duplicated collecting system (HP:0000081)2.65617513
47Vasculitis (HP:0002633)2.65576354
48Increased cerebral lipofuscin (HP:0011813)2.64480947
49Reduced antithrombin III activity (HP:0001976)2.63537239
50Abnormality of the renal collecting system (HP:0004742)2.60914783
51Aplasia/Hypoplasia of the uvula (HP:0010293)2.59279080
52Abnormality of DNA repair (HP:0003254)2.55444513
53Stomatitis (HP:0010280)2.53975910
54Gangrene (HP:0100758)2.53880096
55Increased IgM level (HP:0003496)2.52636398
56Panhypogammaglobulinemia (HP:0003139)2.51088636
57Gingivitis (HP:0000230)2.45266052
58Gastrointestinal infarctions (HP:0005244)2.45082344
59Meckel diverticulum (HP:0002245)2.44914642
60Stomach cancer (HP:0012126)2.42471362
61Myelodysplasia (HP:0002863)2.40037762
62Acute myeloid leukemia (HP:0004808)2.39192933
63IgG deficiency (HP:0004315)2.37676446
64Bone marrow hypocellularity (HP:0005528)2.37326442
65Abnormality of T cells (HP:0002843)2.36436216
66Recurrent pneumonia (HP:0006532)2.36134485
67Abnormality of the ileum (HP:0001549)2.35216893
68Periodontitis (HP:0000704)2.35097015
69Abnormality of the pleura (HP:0002103)2.33025468
70Type I transferrin isoform profile (HP:0003642)2.31519602
71Pancreatic cysts (HP:0001737)2.31292443
72Anorexia (HP:0002039)2.29263496
73Pustule (HP:0200039)2.27633115
74Prolonged bleeding time (HP:0003010)2.26946153
75Encephalitis (HP:0002383)2.26361543
76Vacuolated lymphocytes (HP:0001922)2.26043547
77Combined immunodeficiency (HP:0005387)2.25919927
78Leukocytosis (HP:0001974)2.25439761
79Lymphoma (HP:0002665)2.25413062
80Hypergammaglobulinemia (HP:0010702)2.24075530
81Granulocytopenia (HP:0001913)2.24075394
82Arterial thrombosis (HP:0004420)2.23688824
83Recurrent lower respiratory tract infections (HP:0002783)2.23241395
84Pulmonary infiltrates (HP:0002113)2.23166591
85Abolished electroretinogram (ERG) (HP:0000550)2.22511193
86Eosinophilia (HP:0001880)2.20763858
87Molar tooth sign on MRI (HP:0002419)2.16726530
88Abnormality of midbrain morphology (HP:0002418)2.16726530
89Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.12150191
90Recurrent bronchitis (HP:0002837)2.11472519
91Ectopic kidney (HP:0000086)2.11382674
92Parakeratosis (HP:0001036)2.09005891
93Pallor (HP:0000980)2.07459996
94Decreased electroretinogram (ERG) amplitude (HP:0000654)2.06724691
95Keratitis (HP:0000491)2.06445709
96Cellulitis (HP:0100658)2.06376083
97Abnormal rod and cone electroretinograms (HP:0008323)2.04383471
98Abnormality of the pericardium (HP:0001697)2.03742147
99Polyneuropathy (HP:0001271)2.03559926
100Papilledema (HP:0001085)2.03426597
101Absent rod-and cone-mediated responses on ERG (HP:0007688)2.02461833
102Pancytopenia (HP:0001876)2.02338336
103Pulmonary fibrosis (HP:0002206)2.01517397
104IgA deficiency (HP:0002720)2.00020916
105Attenuation of retinal blood vessels (HP:0007843)1.98000335
1063-Methylglutaconic aciduria (HP:0003535)1.97988841
107Abnormality of eosinophils (HP:0001879)1.97444723
108Chronic diarrhea (HP:0002028)1.96022482
109Agammaglobulinemia (HP:0004432)1.95558607
110Agnosia (HP:0010524)1.95104752
111Autoimmune hemolytic anemia (HP:0001890)1.94985569
112Hemoptysis (HP:0002105)1.94217934
113Type II lissencephaly (HP:0007260)1.93890444
114Keratoconjunctivitis sicca (HP:0001097)1.93479702
115Abnormal number of erythroid precursors (HP:0012131)1.93209946
116Abnormality of the fingertips (HP:0001211)1.92005611
117Abnormality of the pons (HP:0007361)1.91902490
118Leukopenia (HP:0001882)1.91380832
119Gingival bleeding (HP:0000225)1.91151978
120Osteomyelitis (HP:0002754)1.90422743
121Epistaxis (HP:0000421)1.89975189
122Albinism (HP:0001022)1.89172532
123Urticaria (HP:0001025)1.88930662
124Hematochezia (HP:0002573)1.88267155
125Bronchitis (HP:0012387)1.88042648
126Neutropenia (HP:0001875)1.87586904
127Poor head control (HP:0002421)1.87106162
128Abnormality of cells of the lymphoid lineage (HP:0012140)1.86030840
129Lymphopenia (HP:0001888)1.85679004
130Cheilitis (HP:0100825)1.85238923
131Congenital, generalized hypertrichosis (HP:0004540)1.84756771
132Hypoplasia of the pons (HP:0012110)1.84592667
133Severe combined immunodeficiency (HP:0004430)1.84002424
134Exertional dyspnea (HP:0002875)1.83494077
135Abnormality of the columella (HP:0009929)1.83116950
136B lymphocytopenia (HP:0010976)1.82755360
137Abnormality of B cell number (HP:0010975)1.82755360
138Chronic sinusitis (HP:0011109)1.82529937
139Thyroiditis (HP:0100646)1.81601984
140Inflammation of the large intestine (HP:0002037)1.80541157
141Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.78585432
142Abnormality of alanine metabolism (HP:0010916)1.78585432
143Hyperalaninemia (HP:0003348)1.78585432
144Episodic fever (HP:0001954)1.78132827
145Alveolar cell carcinoma (HP:0006519)1.77928241
146Gastrointestinal stroma tumor (HP:0100723)1.74046836

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK44.22222879
2MAP3K143.51475430
3IRAK33.10122116
4FRK2.93765481
5TXK2.58872963
6BLK2.50718646
7CLK12.44228256
8MAP4K12.34083065
9TAOK32.33735867
10KIT2.25071401
11TEC2.11926273
12IKBKE1.99209057
13PIM21.97714880
14CDC71.97281439
15TYK21.95528755
16TBK11.85775948
17JAK31.83169122
18NME21.82439487
19VRK11.80244201
20PLK41.78915849
21IKBKB1.75347034
22BTK1.67715682
23EIF2AK21.56221669
24BMPR21.45802636
25CAMKK21.44712024
26RIPK41.42864837
27MKNK21.42352549
28ZAK1.41489294
29ZAP701.38914857
30ACVR1B1.37525881
31STK161.36657178
32PIM11.35579650
33FES1.32044460
34MKNK11.30035218
35SYK1.27454858
36SRPK11.25234907
37MAP3K61.22662456
38WEE11.22576295
39TLK11.21505271
40IRAK11.19616964
41ATR1.19164952
42MARK31.15647119
43MAP3K131.15021515
44NLK1.14976480
45BMPR1B1.11860862
46EIF2AK11.11726052
47LYN1.10334963
48CHUK1.10298694
49MAP4K21.08035324
50CSF1R1.07828558
51YES11.07426636
52JAK11.06825826
53TRPM71.05065471
54TNIK1.03061931
55NEK91.02693969
56STK41.01599348
57MAP2K31.01383489
58LCK1.00212041
59TTK0.99213960
60ADRBK20.94336293
61CDK80.93309450
62HCK0.88212306
63PRKCQ0.87701308
64IRAK20.86265700
65RPS6KA40.85373700
66CSK0.83405089
67PBK0.82268063
68DAPK20.80981867
69MAP2K60.80929602
70STK100.80740347
71GRK60.78814555
72SIK20.78684942
73EIF2AK30.77438749
74BRSK20.77194021
75MAP3K110.77043557
76TAOK20.76017385
77CDK70.75718421
78CASK0.75115022
79CCNB10.68017114
80BUB10.67977620
81ADRBK10.67566813
82GRK10.62733284
83MAPKAPK30.62028853
84WNK40.61230138
85TGFBR10.61104731
86FGR0.60957071
87GRK70.60821221
88RPS6KA50.60502064
89AURKB0.60297412
90ITK0.59819296
91PLK10.59445755
92MATK0.58970070
93RPS6KA60.58463788
94TSSK60.57208936
95NEK20.56884538
96OXSR10.55828312
97MAP2K20.55451431
98MAPKAPK50.55257596
99MST40.54399552
100MAPK110.53250280
101DYRK30.52813108
102FLT30.52617807
103CDK40.52528775
104VRK20.51835564
105TAF10.51128360
106TAOK10.51116608
107MOS0.50947566
108INSRR0.50839724
109PKN10.49749550
110MAP3K30.48692193
111MAP3K50.48057436
112NUAK10.46772453
113SIK30.43996922
114MELK0.43420239
115TNK20.42912180
116PRKD20.42191625
117CHEK20.41764546
118ATM0.41549791
119MUSK0.40659164
120ABL10.39787990
121STK110.38688856
122PDK10.37570612
123TESK20.37497842
124EPHA30.37002452
125MAPKAPK20.36784909
126JAK20.36636230
127TGFBR20.35058019
128HIPK20.33960624
129CDK30.33722827
130CSNK2A10.33518012
131MAPK150.32148286
132PIK3CG0.31711955
133PTK2B0.28062403
134PINK10.27715078
135PRKCD0.26964497
136IGF1R0.26065259
137CDC42BPA0.26052100

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.35124649
2Homologous recombination_Homo sapiens_hsa034402.88196431
3* Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.70738120
4Mismatch repair_Homo sapiens_hsa034302.51271636
5Fanconi anemia pathway_Homo sapiens_hsa034602.22636289
6Leishmaniasis_Homo sapiens_hsa051402.19662347
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.18865706
8Allograft rejection_Homo sapiens_hsa053302.15799841
9Measles_Homo sapiens_hsa051622.11636921
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.10350416
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.03596380
12Graft-versus-host disease_Homo sapiens_hsa053322.00809439
13Base excision repair_Homo sapiens_hsa034101.94377987
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.91381622
15Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.87633924
16Herpes simplex infection_Homo sapiens_hsa051681.83557017
17Non-homologous end-joining_Homo sapiens_hsa034501.80176310
18NOD-like receptor signaling pathway_Homo sapiens_hsa046211.79760688
19Primary immunodeficiency_Homo sapiens_hsa053401.73885285
20Asthma_Homo sapiens_hsa053101.63380041
21Nucleotide excision repair_Homo sapiens_hsa034201.59248794
22Influenza A_Homo sapiens_hsa051641.59059538
23Antigen processing and presentation_Homo sapiens_hsa046121.53485921
24Pertussis_Homo sapiens_hsa051331.50342901
25Ribosome_Homo sapiens_hsa030101.49129868
26Legionellosis_Homo sapiens_hsa051341.48081489
27Hematopoietic cell lineage_Homo sapiens_hsa046401.45911729
28Osteoclast differentiation_Homo sapiens_hsa043801.42084305
29Pyrimidine metabolism_Homo sapiens_hsa002401.41250052
30Cell cycle_Homo sapiens_hsa041101.37113770
31Other glycan degradation_Homo sapiens_hsa005111.35931238
32One carbon pool by folate_Homo sapiens_hsa006701.35067243
33Malaria_Homo sapiens_hsa051441.34709572
34Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.31233947
35RNA polymerase_Homo sapiens_hsa030201.29932423
36Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.27340293
37p53 signaling pathway_Homo sapiens_hsa041151.21977051
38Autoimmune thyroid disease_Homo sapiens_hsa053201.20232904
39Spliceosome_Homo sapiens_hsa030401.19590539
40Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.18146585
41Tuberculosis_Homo sapiens_hsa051521.16472710
42Jak-STAT signaling pathway_Homo sapiens_hsa046301.15966847
43RNA degradation_Homo sapiens_hsa030181.15636003
44TNF signaling pathway_Homo sapiens_hsa046681.14926442
45Basal transcription factors_Homo sapiens_hsa030221.12997322
46Hepatitis B_Homo sapiens_hsa051611.07256813
47Toxoplasmosis_Homo sapiens_hsa051451.06215348
48Apoptosis_Homo sapiens_hsa042101.02090382
49alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01524991
50Type I diabetes mellitus_Homo sapiens_hsa049400.99988543
51Shigellosis_Homo sapiens_hsa051310.99864871
52B cell receptor signaling pathway_Homo sapiens_hsa046620.99770589
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99676034
54Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96731978
55Rheumatoid arthritis_Homo sapiens_hsa053230.93418906
56Salmonella infection_Homo sapiens_hsa051320.92696487
57Epstein-Barr virus infection_Homo sapiens_hsa051690.90369050
58Staphylococcus aureus infection_Homo sapiens_hsa051500.88572728
59Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.88304049
60Glycosaminoglycan degradation_Homo sapiens_hsa005310.86395452
61Proteasome_Homo sapiens_hsa030500.85864112
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84040748
63Chemokine signaling pathway_Homo sapiens_hsa040620.83381713
64African trypanosomiasis_Homo sapiens_hsa051430.82108195
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.81532149
66Linoleic acid metabolism_Homo sapiens_hsa005910.80751786
67Viral myocarditis_Homo sapiens_hsa054160.76091283
68Hepatitis C_Homo sapiens_hsa051600.75448062
69Protein export_Homo sapiens_hsa030600.75308331
70Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.71535848
71Purine metabolism_Homo sapiens_hsa002300.70014344
72RNA transport_Homo sapiens_hsa030130.69380607
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69378776
74Sphingolipid metabolism_Homo sapiens_hsa006000.68887174
75T cell receptor signaling pathway_Homo sapiens_hsa046600.66873196
76Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.66518759
77Tryptophan metabolism_Homo sapiens_hsa003800.65751216
78Phagosome_Homo sapiens_hsa041450.65748224
79Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.65267144
80Viral carcinogenesis_Homo sapiens_hsa052030.64120011
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63064718
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60859961
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60079067
84Systemic lupus erythematosus_Homo sapiens_hsa053220.59879967
85Acute myeloid leukemia_Homo sapiens_hsa052210.59115934
86Arachidonic acid metabolism_Homo sapiens_hsa005900.58825414
87HTLV-I infection_Homo sapiens_hsa051660.57843492
88Phototransduction_Homo sapiens_hsa047440.57823765
89Lysosome_Homo sapiens_hsa041420.56168714
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55488236
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.55232802
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.54185048
93Small cell lung cancer_Homo sapiens_hsa052220.54064094
94Regulation of autophagy_Homo sapiens_hsa041400.53393042
95Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.52886992
96Dorso-ventral axis formation_Homo sapiens_hsa043200.52877073
97Sulfur metabolism_Homo sapiens_hsa009200.50827238
98Platelet activation_Homo sapiens_hsa046110.49102278
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.47331401
100Caffeine metabolism_Homo sapiens_hsa002320.45786783
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45420322
102Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.44467589
103MicroRNAs in cancer_Homo sapiens_hsa052060.43066600
104Oxidative phosphorylation_Homo sapiens_hsa001900.42594436
105mRNA surveillance pathway_Homo sapiens_hsa030150.42347644
106Nitrogen metabolism_Homo sapiens_hsa009100.41390487
107Chronic myeloid leukemia_Homo sapiens_hsa052200.40976815
108Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40364909
109Pancreatic cancer_Homo sapiens_hsa052120.40173359
110Selenocompound metabolism_Homo sapiens_hsa004500.39826155
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39771318
112Collecting duct acid secretion_Homo sapiens_hsa049660.37476232
113N-Glycan biosynthesis_Homo sapiens_hsa005100.36675527
114Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.35970914
115Adipocytokine signaling pathway_Homo sapiens_hsa049200.32994028
116Prolactin signaling pathway_Homo sapiens_hsa049170.30235346
117Notch signaling pathway_Homo sapiens_hsa043300.29279688
118Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.28045383
119Ether lipid metabolism_Homo sapiens_hsa005650.27731262
120MAPK signaling pathway_Homo sapiens_hsa040100.27376975
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.27173644
122Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.23532990
123VEGF signaling pathway_Homo sapiens_hsa043700.19834099
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.19174478
125Mineral absorption_Homo sapiens_hsa049780.15741364
126FoxO signaling pathway_Homo sapiens_hsa040680.14475957

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