MAST3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.93091488
2locomotory exploration behavior (GO:0035641)5.68188226
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.64623566
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.43024821
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.99795535
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.90475735
7synaptic vesicle exocytosis (GO:0016079)4.84656445
8ionotropic glutamate receptor signaling pathway (GO:0035235)4.80353123
9regulation of neuronal synaptic plasticity (GO:0048168)4.73145709
10regulation of glutamate receptor signaling pathway (GO:1900449)4.71989130
11vocalization behavior (GO:0071625)4.56709872
12glutamate secretion (GO:0014047)4.49024249
13regulation of synaptic vesicle exocytosis (GO:2000300)4.45425752
14regulation of long-term neuronal synaptic plasticity (GO:0048169)4.44738164
15synaptic vesicle docking involved in exocytosis (GO:0016081)4.28956362
16protein localization to synapse (GO:0035418)4.20785782
17neuronal action potential propagation (GO:0019227)4.17303003
18exploration behavior (GO:0035640)4.16202448
19dendritic spine morphogenesis (GO:0060997)4.10518771
20regulation of synapse structural plasticity (GO:0051823)4.10374910
21synaptic transmission, glutamatergic (GO:0035249)4.07247166
22long-term memory (GO:0007616)3.99730809
23regulation of synaptic vesicle transport (GO:1902803)3.99240394
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.97711230
25regulation of excitatory postsynaptic membrane potential (GO:0060079)3.95173261
26regulation of dendritic spine morphogenesis (GO:0061001)3.94203583
27glutamate receptor signaling pathway (GO:0007215)3.94119020
28G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.94044263
29positive regulation of membrane potential (GO:0045838)3.86243290
30regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.84928874
31regulation of synaptic plasticity (GO:0048167)3.82646876
32L-amino acid import (GO:0043092)3.76296041
33neuron-neuron synaptic transmission (GO:0007270)3.75187995
34regulation of B cell receptor signaling pathway (GO:0050855)3.67965765
35neurotransmitter-gated ion channel clustering (GO:0072578)3.66827610
36neurotransmitter secretion (GO:0007269)3.64483114
37regulation of postsynaptic membrane potential (GO:0060078)3.60111460
38regulation of ARF protein signal transduction (GO:0032012)3.57095513
39cellular response to interleukin-15 (GO:0071350)3.53104279
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.51030585
41neuron cell-cell adhesion (GO:0007158)3.51006729
42transmission of nerve impulse (GO:0019226)3.50714040
43long-term synaptic potentiation (GO:0060291)3.49710477
44neuromuscular process controlling balance (GO:0050885)3.48928670
45regulation of Rap GTPase activity (GO:0032317)3.48772467
46response to interleukin-15 (GO:0070672)3.46634056
47layer formation in cerebral cortex (GO:0021819)3.44565017
48cellular potassium ion homeostasis (GO:0030007)3.42893700
49regulation of dendritic spine development (GO:0060998)3.42134972
50gamma-aminobutyric acid transport (GO:0015812)3.41905086
51central nervous system myelination (GO:0022010)3.40663817
52axon ensheathment in central nervous system (GO:0032291)3.40663817
53positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.37019270
54negative regulation of cell killing (GO:0031342)3.35016809
55negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.35016809
56positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.34731251
57nerve growth factor signaling pathway (GO:0038180)3.32980510
58sodium ion export (GO:0071436)3.32463190
59glycine transport (GO:0015816)3.31522944
60positive regulation of gamma-delta T cell activation (GO:0046645)3.31473603
61neuronal ion channel clustering (GO:0045161)3.28013254
62positive regulation of Rap GTPase activity (GO:0032854)3.23518559
63regulation of ARF GTPase activity (GO:0032312)3.23262661
64synaptic vesicle endocytosis (GO:0048488)3.22870614
65positive regulation of neurotransmitter secretion (GO:0001956)3.22573450
66chemosensory behavior (GO:0007635)3.20966963
67antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.19836996
68dendritic spine organization (GO:0097061)3.19027095
69positive regulation of dendritic spine development (GO:0060999)3.14525608
70antigen processing and presentation of endogenous antigen (GO:0019883)3.14360601
71negative regulation of lymphocyte mediated immunity (GO:0002707)3.13811569
72regulation of synaptic transmission, glutamatergic (GO:0051966)3.12365003
73negative regulation of synaptic transmission, GABAergic (GO:0032229)3.11950371
74positive regulation of synaptic transmission, GABAergic (GO:0032230)3.11051003
75signal complex assembly (GO:0007172)3.10735064
76macrophage activation involved in immune response (GO:0002281)3.09107350
77positive regulation of neurotransmitter transport (GO:0051590)3.08020114
78prepulse inhibition (GO:0060134)3.05554605
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.05446447
80adenosine receptor signaling pathway (GO:0001973)3.04892649
81positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.02825567
82regulation of neurotransmitter secretion (GO:0046928)3.02524572
83positive regulation by organism of defense response of other organism involved in symbiotic interact3.01028785
84modulation by symbiont of host immune response (GO:0052553)3.01028785
85positive regulation by symbiont of host defense response (GO:0052509)3.01028785
86modulation by symbiont of host defense response (GO:0052031)3.01028785
87modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.01028785
88modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.01028785
89negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.00379985
90synaptic transmission, dopaminergic (GO:0001963)3.00282883
91membrane depolarization (GO:0051899)2.99907731
92adult walking behavior (GO:0007628)2.98932105
93auditory behavior (GO:0031223)2.98826589
94neurotransmitter transport (GO:0006836)2.96041173
95regulation of beta-amyloid formation (GO:1902003)2.95797211
96peptidyl-tyrosine autophosphorylation (GO:0038083)2.95401110
97negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.95350046
98regulation of vesicle fusion (GO:0031338)2.95103808
99learning (GO:0007612)2.94792560
100neuromuscular process controlling posture (GO:0050884)2.94045441
101regulation of synaptic transmission (GO:0050804)2.91561577
102activation of protein kinase A activity (GO:0034199)2.91174472
103negative regulation of protein oligomerization (GO:0032460)2.90403714
104vesicle transport along microtubule (GO:0047496)2.90114258
105positive regulation of synaptic transmission (GO:0050806)2.89238077
106leukocyte aggregation (GO:0070486)2.87691016
107regulation of neurotransmitter levels (GO:0001505)2.87361123
108regulation of neurotransmitter transport (GO:0051588)2.87117884
109dendrite morphogenesis (GO:0048813)2.86943079
110regulation of female receptivity (GO:0045924)2.86430396
111behavioral fear response (GO:0001662)2.85488524
112behavioral defense response (GO:0002209)2.85488524
113proline transport (GO:0015824)2.84518282
114visual learning (GO:0008542)2.83979032
115regulation of glutamate secretion (GO:0014048)2.83453302
116cerebellar Purkinje cell differentiation (GO:0021702)2.82954455
117antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.81902252
118neuron recognition (GO:0008038)2.79720486
119regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.76927345
120negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.76810194
121negative regulation of leukocyte mediated immunity (GO:0002704)2.75219544
122behavioral response to cocaine (GO:0048148)2.75174839
123adaptation of signaling pathway (GO:0023058)2.74957124
124neuromuscular process (GO:0050905)2.74260085
125neutrophil activation involved in immune response (GO:0002283)2.73731372
126regulation of amyloid precursor protein catabolic process (GO:1902991)2.73645655
127regulation of exocytosis (GO:0017157)2.64527915
128negative regulation of T cell mediated immunity (GO:0002710)2.63544948
129leukocyte migration involved in inflammatory response (GO:0002523)2.62649351
130microglial cell activation (GO:0001774)2.62478759
131activated T cell proliferation (GO:0050798)2.57718599
132detection of other organism (GO:0098543)2.55893938
133regulation of gamma-delta T cell activation (GO:0046643)2.54350739
134detection of calcium ion (GO:0005513)2.50518185
135negative regulation of cAMP-mediated signaling (GO:0043951)2.49603909
136neutrophil activation (GO:0042119)2.48289018
137detection of bacterium (GO:0016045)2.47478146
138regulation of regulated secretory pathway (GO:1903305)2.44757667
139negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.44586637
140negative regulation of T-helper cell differentiation (GO:0045623)2.44586637
141negative thymic T cell selection (GO:0045060)2.42254384
142cellular extravasation (GO:0045123)2.42227716
143membrane depolarization during action potential (GO:0086010)2.41181906
144myeloid cell activation involved in immune response (GO:0002275)2.40556498
145macrophage activation (GO:0042116)2.40076182
146positive regulation of fibroblast migration (GO:0010763)2.38724126
147negative T cell selection (GO:0043383)2.38382157
148production of molecular mediator involved in inflammatory response (GO:0002532)2.37308088
149positive regulation of mast cell activation (GO:0033005)2.36816218
150B cell receptor signaling pathway (GO:0050853)2.35394677
151regulation of interferon-beta biosynthetic process (GO:0045357)2.35349504
152negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.32627817
153regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.26104561
154regulation of gamma-delta T cell differentiation (GO:0045586)2.25501070
155leukocyte degranulation (GO:0043299)2.25112405

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.45195572
2* RARB_27405468_Chip-Seq_BRAIN_Mouse3.48048741
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.08210690
4DROSHA_22980978_ChIP-Seq_HELA_Human3.06387575
5GBX2_23144817_ChIP-Seq_PC3_Human2.92232217
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.77601295
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75833932
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.67671418
9REST_21632747_ChIP-Seq_MESCs_Mouse2.65758813
10MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.59500171
11IKZF1_21737484_ChIP-ChIP_HCT116_Human2.55131302
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.46345614
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.45777861
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.42621235
15EZH2_18974828_ChIP-Seq_MESCs_Mouse2.42621235
16EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.33982827
17VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.32771131
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.32538281
19JARID2_20075857_ChIP-Seq_MESCs_Mouse2.31665787
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.23350188
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.21583620
22IRF8_21731497_ChIP-ChIP_J774_Mouse2.13204084
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.09867357
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.07558683
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.04512137
26* EZH2_27294783_Chip-Seq_ESCs_Mouse2.04286321
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.02695794
28EZH2_27304074_Chip-Seq_ESCs_Mouse1.98679283
29FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.87641773
30IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.84929953
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81638916
32DNAJC2_21179169_ChIP-ChIP_NT2_Human1.69839259
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.67495636
34FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63275272
35EED_16625203_ChIP-ChIP_MESCs_Mouse1.58696416
36IRF8_27001747_Chip-Seq_BMDM_Mouse1.57542719
37GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.55620183
38LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.54293350
39AR_21572438_ChIP-Seq_LNCaP_Human1.51514328
40MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.49762583
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45906220
42* KDM2B_26808549_Chip-Seq_K562_Human1.43478340
43* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.43142453
44ERG_21242973_ChIP-ChIP_JURKAT_Human1.40499944
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.40277037
46EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.35657891
47WT1_25993318_ChIP-Seq_PODOCYTE_Human1.33885430
48WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.32524952
49RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29372251
50SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.27800124
51SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.25881416
52* IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.25523280
53* KDM2B_26808549_Chip-Seq_DND41_Human1.24386221
54* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.24254713
55THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.23678650
56RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.22316509
57FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.19447189
58LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.19260694
59RING1B_27294783_Chip-Seq_ESCs_Mouse1.18108606
60GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.17567546
61P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17411828
62SMAD4_21799915_ChIP-Seq_A2780_Human1.16605816
63NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15774821
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15374299
65PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15189617
66GATA3_27048872_Chip-Seq_THYMUS_Human1.14512225
67ZFP281_18757296_ChIP-ChIP_E14_Mouse1.13626176
68CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.12338048
69SOX2_21211035_ChIP-Seq_LN229_Gbm1.11082500
70NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10882598
71SPI1_23127762_ChIP-Seq_K562_Human1.10219745
72PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.10179204
73GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09574700
74TAF15_26573619_Chip-Seq_HEK293_Human1.09342901
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08803324
76KDM2B_26808549_Chip-Seq_JURKAT_Human1.08302008
77AR_19668381_ChIP-Seq_PC3_Human1.06936842
78RUNX_20019798_ChIP-Seq_JUKART_Human1.06734342
79* LXR_22292898_ChIP-Seq_THP-1_Human1.06677198
80GATA3_26560356_Chip-Seq_TH2_Human1.06007944
81STAT3_23295773_ChIP-Seq_U87_Human1.04646539
82ZFP281_27345836_Chip-Seq_ESCs_Mouse1.03100794
83SMRT_27268052_Chip-Seq_Bcells_Human1.02581715
84VDR_24787735_ChIP-Seq_THP-1_Human1.01075998
85SMAD3_21741376_ChIP-Seq_EPCs_Human1.00720729
86CTCF_27219007_Chip-Seq_Bcells_Human1.00544434
87KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00090414
88VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.00064799
89ARNT_22903824_ChIP-Seq_MCF-7_Human0.99302466
90PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.98714993
91TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98456103
92ZFP57_27257070_Chip-Seq_ESCs_Mouse0.96989659
93EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.96560861
94BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95800666
95PRDM14_20953172_ChIP-Seq_ESCs_Human0.95634288
96GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95607496
97RING1B_27294783_Chip-Seq_NPCs_Mouse0.95586579
98AHR_22903824_ChIP-Seq_MCF-7_Human0.95570648
99KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.94433083
100SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94140776
101BCAT_22108803_ChIP-Seq_LS180_Human0.94072105
102KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93150249
103TET1_21490601_ChIP-Seq_MESCs_Mouse0.92710361
104TCF4_23295773_ChIP-Seq_U87_Human0.92621379
105ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92411008
106SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92125476
107CTBP2_25329375_ChIP-Seq_LNCAP_Human0.91759344
108ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91583001
109SMAD_19615063_ChIP-ChIP_OVARY_Human0.90914328
110GATA1_19941826_ChIP-Seq_K562_Human0.90501599
111PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.90460779
112AR_25329375_ChIP-Seq_VCAP_Human0.90214798
113OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89604559
114MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.89329253
115DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88886058
116GATA1_19941827_ChIP-Seq_MEL_Mouse0.88493295
117NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.88232292
118* OCT4_19829295_ChIP-Seq_ESCs_Human0.87226709
119MYB_26560356_Chip-Seq_TH2_Human0.86899705
120BP1_19119308_ChIP-ChIP_Hs578T_Human0.86817141
121TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86468840
122FLI1_27457419_Chip-Seq_LIVER_Mouse0.86145630
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.86100947
124TP53_16413492_ChIP-PET_HCT116_Human0.85971670
125* STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.85545107
126KLF4_19829295_ChIP-Seq_ESCs_Human0.84052056
127SMAD3_21741376_ChIP-Seq_HESCs_Human0.83768795
128RXR_22108803_ChIP-Seq_LS180_Human0.83571271
129CDX2_19796622_ChIP-Seq_MESCs_Mouse0.83567616
130P300_19829295_ChIP-Seq_ESCs_Human0.83129070
131RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.82836892
132LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82573035
133CTNNB1_20460455_ChIP-Seq_HCT116_Human0.82089628
134SCL_19346495_ChIP-Seq_HPC-7_Human0.81943844
135E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.81147062
136TCF7_22412390_ChIP-Seq_EML_Mouse0.81063986
137SMAD3_21741376_ChIP-Seq_ESCs_Human0.81001537
138TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.80428097
139TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80390861
140POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.80390861
141SMAD4_21741376_ChIP-Seq_HESCs_Human0.80303926
142BCOR_27268052_Chip-Seq_Bcells_Human0.77525205
143FLI1_21867929_ChIP-Seq_TH2_Mouse0.76417580
144TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.76315079
145NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.76114670
146RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.75366177
147* SMAD4_21741376_ChIP-Seq_ESCs_Human0.75075569

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.57061303
2MP0003880_abnormal_central_pattern4.92398478
3MP0003635_abnormal_synaptic_transmissio4.17783415
4MP0002822_catalepsy3.92453973
5MP0004270_analgesia3.76979121
6MP0009745_abnormal_behavioral_response3.48161091
7MP0002063_abnormal_learning/memory/cond3.36748294
8MP0002064_seizures3.30580759
9MP0002572_abnormal_emotion/affect_behav2.76813262
10MP0002272_abnormal_nervous_system2.68152283
11MP0001486_abnormal_startle_reflex2.65912851
12MP0003724_increased_susceptibility_to2.57102226
13MP0001968_abnormal_touch/_nociception2.41379002
14MP0009046_muscle_twitch2.39342689
15MP0003329_amyloid_beta_deposits2.37308018
16MP0005423_abnormal_somatic_nervous2.34907087
17MP0001501_abnormal_sleep_pattern2.16263749
18MP0003195_calcinosis2.14407743
19MP0000920_abnormal_myelination2.09704824
20MP0008569_lethality_at_weaning2.03987698
21MP0002734_abnormal_mechanical_nocicepti2.01789403
22MP0001986_abnormal_taste_sensitivity1.94184108
23MP0001440_abnormal_grooming_behavior1.85818427
24MP0001835_abnormal_antigen_presentation1.84382290
25MP0003436_decreased_susceptibility_to1.83063374
26MP0002736_abnormal_nociception_after1.80430651
27MP0009780_abnormal_chondrocyte_physiolo1.78862801
28MP0001970_abnormal_pain_threshold1.75104444
29MP0003075_altered_response_to1.72853165
30MP0004885_abnormal_endolymph1.72676771
31MP0003787_abnormal_imprinting1.71536439
32MP0003690_abnormal_glial_cell1.69433904
33MP0001790_abnormal_immune_system1.67709551
34MP0005387_immune_system_phenotype1.67709551
35MP0002735_abnormal_chemical_nociception1.67134387
36MP0003633_abnormal_nervous_system1.66418326
37MP0005409_darkened_coat_color1.65687707
38MP0004811_abnormal_neuron_physiology1.65579483
39MP0005646_abnormal_pituitary_gland1.63841558
40MP0002909_abnormal_adrenal_gland1.61947582
41MP0000685_abnormal_immune_system1.61700396
42MP0003879_abnormal_hair_cell1.60395372
43MP0002733_abnormal_thermal_nociception1.57510871
44MP0005000_abnormal_immune_tolerance1.55345961
45MP0002067_abnormal_sensory_capabilities1.55186358
46MP0006082_CNS_inflammation1.55168024
47MP0001800_abnormal_humoral_immune1.54891406
48MP0005386_behavior/neurological_phenoty1.54033912
49MP0004924_abnormal_behavior1.54033912
50MP0002557_abnormal_social/conspecific_i1.47187865
51MP0000955_abnormal_spinal_cord1.44407608
52MP0001529_abnormal_vocalization1.44011248
53MP0002419_abnormal_innate_immunity1.43383960
54MP0003122_maternal_imprinting1.40899499
55MP0001905_abnormal_dopamine_level1.40611153
56MP0008961_abnormal_basal_metabolism1.38235795
57MP0002723_abnormal_immune_serum1.36633315
58MP0000604_amyloidosis1.36222969
59MP0002693_abnormal_pancreas_physiology1.36193409
60MP0002066_abnormal_motor_capabilities/c1.36143100
61MP0005025_abnormal_response_to1.35670379
62MP0003631_nervous_system_phenotype1.35475747
63MP0004510_myositis1.34774749
64MP0003172_abnormal_lysosome_physiology1.32698265
65MP0008874_decreased_physiological_sensi1.31239091
66MP0002420_abnormal_adaptive_immunity1.30173835
67MP0001819_abnormal_immune_cell1.27545054
68MP0009785_altered_susceptibility_to1.27013528
69MP0000778_abnormal_nervous_system1.26221539
70MP0002882_abnormal_neuron_morphology1.25434085
71MP0004142_abnormal_muscle_tone1.23278670
72MP0000569_abnormal_digit_pigmentation1.19825836
73MP0002452_abnormal_antigen_presenting1.16756000
74MP0001502_abnormal_circadian_rhythm1.15933113
75MP0002229_neurodegeneration1.14177149
76MP0002184_abnormal_innervation1.13319544
77MP0003634_abnormal_glial_cell1.11637997
78MP0004858_abnormal_nervous_system1.11455301
79MP0002876_abnormal_thyroid_physiology1.10490615
80MP0005645_abnormal_hypothalamus_physiol1.07660459
81MP0005379_endocrine/exocrine_gland_phen1.05405629
82MP0004742_abnormal_vestibular_system1.03368173
83MP0008872_abnormal_physiological_respon1.02569420
84MP0005310_abnormal_salivary_gland1.01591055
85MP0004381_abnormal_hair_follicle0.99331354
86MP0003763_abnormal_thymus_physiology0.96304415
87MP0001984_abnormal_olfaction0.95974073
88MP0002928_abnormal_bile_duct0.95184443
89MP0002069_abnormal_eating/drinking_beha0.94763434
90MP0002148_abnormal_hypersensitivity_rea0.93833664
91MP0003632_abnormal_nervous_system0.93398332
92MP0005535_abnormal_body_temperature0.93219884
93MP0003123_paternal_imprinting0.93018178
94MP0001533_abnormal_skeleton_physiology0.92229441
95MP0002277_abnormal_respiratory_mucosa0.91249345
96MP0002152_abnormal_brain_morphology0.89941165
97MP0000716_abnormal_immune_system0.88984548
98MP0002398_abnormal_bone_marrow0.85665555
99MP0001845_abnormal_inflammatory_respons0.85065457
100MP0001485_abnormal_pinna_reflex0.84102004
101MP0002163_abnormal_gland_morphology0.82068866
102MP0005058_abnormal_lysosome_morphology0.81848927
103MP0001944_abnormal_pancreas_morphology0.81677947
104MP0002405_respiratory_system_inflammati0.80894322
105MP0003303_peritoneal_inflammation0.80180592
106MP0003183_abnormal_peptide_metabolism0.79708131
107MP0002078_abnormal_glucose_homeostasis0.79254843
108MP0010386_abnormal_urinary_bladder0.79012583
109MP0005167_abnormal_blood-brain_barrier0.77401065
110MP0005166_decreased_susceptibility_to0.73303791
111MP0000013_abnormal_adipose_tissue0.72986601
112MP0001177_atelectasis0.70821673
113MP0001963_abnormal_hearing_physiology0.67377302
114MP0001765_abnormal_ion_homeostasis0.61878145
115MP0000015_abnormal_ear_pigmentation0.61845159
116MP0004085_abnormal_heartbeat0.60746062
117MP0001664_abnormal_digestion0.59063997
118MP0003300_gastrointestinal_ulcer0.56855546
119MP0004043_abnormal_pH_regulation0.55419371
120MP0003283_abnormal_digestive_organ0.55248242
121MP0006276_abnormal_autonomic_nervous0.53971170
122MP0005174_abnormal_tail_pigmentation0.53555469
123MP0002090_abnormal_vision0.52719121
124MP0003045_fibrosis0.52716151
125MP0005671_abnormal_response_to0.49750191
126MP0005551_abnormal_eye_electrophysiolog0.49133055
127MP0000747_muscle_weakness0.47846702
128MP0001188_hyperpigmentation0.47308596
129MP0005464_abnormal_platelet_physiology0.45677508
130MP0010769_abnormal_survival0.45626102
131MP0003956_abnormal_body_size0.45079388
132MP0000003_abnormal_adipose_tissue0.44788547
133MP0010234_abnormal_vibrissa_follicle0.44554296
134MP0008877_abnormal_DNA_methylation0.44271602
135MP0010768_mortality/aging0.42668988
136MP0003866_abnormal_defecation0.42560671
137MP0002752_abnormal_somatic_nervous0.41933499

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.28836290
2Myokymia (HP:0002411)7.21309943
3Focal seizures (HP:0007359)5.43041996
4Visual hallucinations (HP:0002367)5.04520811
5Supranuclear gaze palsy (HP:0000605)4.68094437
6Stomatitis (HP:0010280)4.30089586
7Neurofibrillary tangles (HP:0002185)4.19279898
8Epileptic encephalopathy (HP:0200134)4.05241455
9Dysmetria (HP:0001310)3.90867179
10Cerebral inclusion bodies (HP:0100314)3.77430624
11Papilledema (HP:0001085)3.69997756
12Ankle clonus (HP:0011448)3.63762243
13Action tremor (HP:0002345)3.62282644
14Eczematoid dermatitis (HP:0000976)3.57534726
15Atonic seizures (HP:0010819)3.49604054
16Postural instability (HP:0002172)3.46209472
17Absence seizures (HP:0002121)3.45941760
18Dialeptic seizures (HP:0011146)3.44704220
19Myositis (HP:0100614)3.41025839
20Poor eye contact (HP:0000817)3.37822862
21Retrobulbar optic neuritis (HP:0100654)3.37723768
22Optic neuritis (HP:0100653)3.37723768
23Spastic gait (HP:0002064)3.37557097
24Broad-based gait (HP:0002136)3.34922098
25Impaired vibration sensation in the lower limbs (HP:0002166)3.34231055
26Depression (HP:0000716)3.29224262
27Recurrent bacterial skin infections (HP:0005406)3.27765790
28Orchitis (HP:0100796)3.27749586
29Febrile seizures (HP:0002373)3.24424491
30Intention tremor (HP:0002080)3.24205203
31Progressive cerebellar ataxia (HP:0002073)3.23938258
32Urinary bladder sphincter dysfunction (HP:0002839)3.22360970
33Generalized tonic-clonic seizures (HP:0002069)3.19178443
34Impaired social interactions (HP:0000735)3.13758891
35Abnormal social behavior (HP:0012433)3.13758891
36Recurrent abscess formation (HP:0002722)3.13595071
37Gaze-evoked nystagmus (HP:0000640)3.12046422
38Urinary urgency (HP:0000012)3.08066969
39Episodic fever (HP:0001954)3.04116388
40Truncal ataxia (HP:0002078)3.03427107
41Dysdiadochokinesis (HP:0002075)3.01817737
42Anxiety (HP:0000739)2.98641676
43Mutism (HP:0002300)2.95844412
44Scanning speech (HP:0002168)2.95216211
45Hypochromic microcytic anemia (HP:0004840)2.94277230
46Stereotypic behavior (HP:0000733)2.84198597
47Elevated erythrocyte sedimentation rate (HP:0003565)2.84140908
48Abnormality of macrophages (HP:0004311)2.82449259
49Hemiplegia (HP:0002301)2.81296833
50Impaired smooth pursuit (HP:0007772)2.80598312
51Annular pancreas (HP:0001734)2.79014700
52Abnormal delayed hypersensitivity skin test (HP:0002963)2.78663087
53Torticollis (HP:0000473)2.77287020
54Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.74424961
55Degeneration of the lateral corticospinal tracts (HP:0002314)2.74424961
56Diplopia (HP:0000651)2.70386794
57Abnormality of binocular vision (HP:0011514)2.70386794
58Recurrent fungal infections (HP:0002841)2.68753440
59Peripheral hypomyelination (HP:0007182)2.65286101
60Focal dystonia (HP:0004373)2.64786626
61Hyperventilation (HP:0002883)2.64135051
62Recurrent gram-negative bacterial infections (HP:0005420)2.60226746
63Onion bulb formation (HP:0003383)2.56614716
64Abnormality of the corticospinal tract (HP:0002492)2.55172392
65Neuronal loss in central nervous system (HP:0002529)2.54494838
66Bradykinesia (HP:0002067)2.53589155
67Gastrointestinal infarctions (HP:0005244)2.51904720
68Increased circulating renin level (HP:0000848)2.47765022
69Ketoacidosis (HP:0001993)2.47049187
70Meningitis (HP:0001287)2.46184716
71Recurrent skin infections (HP:0001581)2.45272589
72Slow saccadic eye movements (HP:0000514)2.44191791
73Recurrent cutaneous fungal infections (HP:0011370)2.42476506
74Chronic mucocutaneous candidiasis (HP:0002728)2.42476506
75Abnormality of the lower motor neuron (HP:0002366)2.41615510
76Genetic anticipation (HP:0003743)2.41066501
77Abnormal eating behavior (HP:0100738)2.40989424
78Prolonged bleeding time (HP:0003010)2.38322537
79Hypochromic anemia (HP:0001931)2.36184658
80Insomnia (HP:0100785)2.35430149
81Progressive inability to walk (HP:0002505)2.35141115
82Amblyopia (HP:0000646)2.34184805
83Abnormality of ocular smooth pursuit (HP:0000617)2.33409524
84Craniofacial dystonia (HP:0012179)2.32752615
85Ventricular fibrillation (HP:0001663)2.31999248
86Keratoconjunctivitis (HP:0001096)2.29399013
87Generalized myoclonic seizures (HP:0002123)2.28085851
88Impaired vibratory sensation (HP:0002495)2.27932563
89Abnormality of saccadic eye movements (HP:0000570)2.25618338
90Encephalitis (HP:0002383)2.24889698
91Vasculitis (HP:0002633)2.23085418
92Rigidity (HP:0002063)2.22423751
93Termporal pattern (HP:0011008)2.22193393
94Insidious onset (HP:0003587)2.22193393
95Abnormality of the periventricular white matter (HP:0002518)2.22010498
96Lower limb muscle weakness (HP:0007340)2.20176119
97Pointed chin (HP:0000307)2.20034534
98Hypomagnesemia (HP:0002917)2.19669007
99Clonus (HP:0002169)2.19399661
100Epileptiform EEG discharges (HP:0011182)2.18807281
101Mediastinal lymphadenopathy (HP:0100721)2.18262618
102Drooling (HP:0002307)2.17485926
103Excessive salivation (HP:0003781)2.17485926
104Megalencephaly (HP:0001355)2.16147000
105Keratoconjunctivitis sicca (HP:0001097)2.15716674
106Petechiae (HP:0000967)2.15058416
107Pulmonary infiltrates (HP:0002113)2.14326075
108Macroorchidism (HP:0000053)2.14264148
109Rapidly progressive (HP:0003678)2.12778356
110Spastic tetraparesis (HP:0001285)2.09548230
111Psychosis (HP:0000709)2.08794816
112Hemiparesis (HP:0001269)2.08597551
113Hemoptysis (HP:0002105)2.08516321
114Ankyloglossia (HP:0010296)2.06631890
115Bowel incontinence (HP:0002607)2.06447376
116Chronic obstructive pulmonary disease (HP:0006510)2.06410623
117Obstructive lung disease (HP:0006536)2.06410623
118EEG with generalized epileptiform discharges (HP:0011198)2.05968420
119Dysmetric saccades (HP:0000641)2.05076772
120Ocular albinism (HP:0001107)2.03675849
121Increased CSF protein (HP:0002922)2.02063941
122Hypoglycemic seizures (HP:0002173)2.01802960
123Hypsarrhythmia (HP:0002521)2.00359314
124Agitation (HP:0000713)1.98893176
125Delusions (HP:0000746)1.98160304
126Chest pain (HP:0100749)1.96857659
127Hyperinsulinemic hypoglycemia (HP:0000825)1.96711580
128Iris hypopigmentation (HP:0007730)1.93581856
129Panhypogammaglobulinemia (HP:0003139)1.92750221
130Resting tremor (HP:0002322)1.92125204
131Pulmonary embolism (HP:0002204)1.91687513
132Abnormality of the pancreatic islet cells (HP:0006476)1.91651992
133Abnormality of endocrine pancreas physiology (HP:0012093)1.91651992
134Obstructive sleep apnea (HP:0002870)1.91509424
135Memory impairment (HP:0002354)1.91384939
136Apathy (HP:0000741)1.91320433
137Hematochezia (HP:0002573)1.91155154
138Polyphagia (HP:0002591)1.90272514
139Gait ataxia (HP:0002066)1.89641050
140Clumsiness (HP:0002312)1.89465350
141Lower limb amyotrophy (HP:0007210)1.88898049
142Absent speech (HP:0001344)1.86693645
143Thickened helices (HP:0000391)1.85934249
144Abnormal large intestine physiology (HP:0012700)1.85518304
145Akinesia (HP:0002304)1.84698720
146Abnormality of oral frenula (HP:0000190)1.82755051
147Status epilepticus (HP:0002133)1.82003668
148Widely spaced teeth (HP:0000687)1.81581972
149Pustule (HP:0200039)1.81454970
150Spontaneous hematomas (HP:0007420)1.80764701
151Large for gestational age (HP:0001520)1.79626062
152Limb dystonia (HP:0002451)1.78986177
153Inability to walk (HP:0002540)1.78659881
154Global brain atrophy (HP:0002283)1.78172363
155Abnormal drinking behavior (HP:0030082)1.77907431
156Polydipsia (HP:0001959)1.77907431
157Tetraplegia (HP:0002445)1.77883660
158Microcytic anemia (HP:0001935)1.74445625
159Abnormal rod and cone electroretinograms (HP:0008323)1.70083596

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.35773162
2NTRK34.03493046
3MAP3K93.42110834
4FRK3.40617769
5RIPK42.72758110
6MAP3K132.31350652
7DAPK22.26918599
8PRKD32.25229976
9KSR22.23380138
10FES2.09357139
11PRPF4B2.06716677
12PAK62.02230228
13SIK22.00419597
14MINK11.87479004
15CAMKK11.84757026
16MAP3K41.80296935
17CDK191.72225734
18NTRK11.68355674
19CDK51.63916857
20TXK1.61156399
21NTRK21.57297944
22TNIK1.54408799
23IRAK41.53126646
24UHMK11.50874591
25DAPK11.41921616
26BLK1.40726942
27TYK21.40349691
28MAP2K71.39655584
29TAOK11.31626122
30PRKCH1.29977651
31TYRO31.28235335
32MARK21.24677460
33KSR11.24573837
34OXSR11.21695646
35CAMK11.19048945
36MAP3K111.18938713
37PTK2B1.16692519
38MARK11.16551792
39MAP3K21.15876839
40MAP2K61.12076654
41JAK11.10862593
42MAP2K41.10763994
43ARAF1.09537220
44PNCK1.05623179
45MAP3K71.03358480
46PDK11.02987399
47FGFR31.02887238
48CLK11.02559798
49CAMK2B1.01217943
50CSK0.97680371
51CAMK1G0.96770034
52ALK0.95546601
53FGR0.94575854
54SGK2230.94296643
55SGK4940.94296643
56SIK30.94183853
57PDPK10.93473474
58TAOK30.92729573
59TNK20.92108282
60STK110.91700609
61MAP4K10.91449326
62WNK30.90867879
63MAP3K120.90755198
64RAF10.88588854
65CDK180.88582655
66JAK20.88340482
67ITK0.87614616
68CDK150.87492517
69PRKD20.87285518
70IKBKE0.86666896
71STK380.86397890
72PRKCG0.86143380
73MAP2K30.85001232
74STK390.83886403
75NEK60.83091565
76MAP3K10.81741207
77ZAP700.81666778
78GRK50.81525653
79MAP4K20.81166774
80BTK0.80846238
81RET0.80662959
82CDK11A0.79893701
83CAMK2A0.78315757
84FGFR20.78142914
85CDK140.75481011
86LYN0.75023721
87GRK60.74522627
88MAPKAPK50.73805936
89SYK0.71917978
90ERN10.71896954
91CSNK1G20.71889353
92HCK0.69987670
93CASK0.69044978
94FYN0.68172955
95SGK10.67470220
96JAK30.67393246
97CAMKK20.67078477
98LCK0.66365404
99IRAK20.66089469
100GRK10.65854382
101SGK30.64651714
102BMPR20.63956125
103MAPK130.62559726
104PRKCQ0.62548630
105MARK30.61720542
106CAMK40.60567337
107PKN10.60301503
108DMPK0.60064809
109WNK10.59632832
110PRKG20.58007920
111EPHB10.57909617
112IKBKB0.54826381
113ADRBK20.54782081
114PHKG10.52745346
115PHKG20.52745346
116CSNK1A1L0.52616505
117DYRK1A0.51388438
118YES10.50919705
119PLK20.48586593
120MAPK100.48071280
121TEC0.46468693
122PAK30.45430702
123RPS6KA30.45207387
124SGK20.44640440
125MAP3K30.44603352
126MAPK70.44192227
127NLK0.43278708
128HIPK20.42020497
129MAPK120.40573159
130CSNK1G30.39087426
131PINK10.38825156
132CAMK2D0.38068351
133PRKCZ0.37540273
134PRKD10.37166664
135MAP3K60.36734329
136ROCK20.36689938

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047402.89151289
2Nicotine addiction_Homo sapiens_hsa050332.88634022
3Long-term potentiation_Homo sapiens_hsa047202.75427017
4Circadian entrainment_Homo sapiens_hsa047132.65322656
5Glutamatergic synapse_Homo sapiens_hsa047242.61611409
6Synaptic vesicle cycle_Homo sapiens_hsa047212.53920504
7Amphetamine addiction_Homo sapiens_hsa050312.51790179
8Morphine addiction_Homo sapiens_hsa050322.48586481
9GABAergic synapse_Homo sapiens_hsa047272.41279748
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.36640337
11Salivary secretion_Homo sapiens_hsa049702.15891913
12Dopaminergic synapse_Homo sapiens_hsa047282.08526867
13Maturity onset diabetes of the young_Homo sapiens_hsa049502.00270576
14Aldosterone synthesis and secretion_Homo sapiens_hsa049251.98827539
15Nitrogen metabolism_Homo sapiens_hsa009101.94832317
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.94266619
17Gastric acid secretion_Homo sapiens_hsa049711.93247741
18Cholinergic synapse_Homo sapiens_hsa047251.91695182
19Insulin secretion_Homo sapiens_hsa049111.91432618
20Cocaine addiction_Homo sapiens_hsa050301.87389578
21Renin secretion_Homo sapiens_hsa049241.63068673
22Oxytocin signaling pathway_Homo sapiens_hsa049211.61355573
23Long-term depression_Homo sapiens_hsa047301.60552999
24Calcium signaling pathway_Homo sapiens_hsa040201.56425028
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.50218722
26Phosphatidylinositol signaling system_Homo sapiens_hsa040701.50036492
27Serotonergic synapse_Homo sapiens_hsa047261.46071395
28GnRH signaling pathway_Homo sapiens_hsa049121.45529705
29Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.41163840
30Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.40113056
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.38506119
32cAMP signaling pathway_Homo sapiens_hsa040241.35061313
33Regulation of autophagy_Homo sapiens_hsa041401.31101246
34Graft-versus-host disease_Homo sapiens_hsa053321.31019274
35Taste transduction_Homo sapiens_hsa047421.30364269
36Type II diabetes mellitus_Homo sapiens_hsa049301.30040258
37Allograft rejection_Homo sapiens_hsa053301.28545082
38Leishmaniasis_Homo sapiens_hsa051401.28094163
39Staphylococcus aureus infection_Homo sapiens_hsa051501.27158467
40Glioma_Homo sapiens_hsa052141.22924186
41Autoimmune thyroid disease_Homo sapiens_hsa053201.19687105
42ErbB signaling pathway_Homo sapiens_hsa040121.15641844
43Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.13543843
44Pancreatic secretion_Homo sapiens_hsa049721.11018379
45Phospholipase D signaling pathway_Homo sapiens_hsa040721.09252692
46Gap junction_Homo sapiens_hsa045401.09164270
47Estrogen signaling pathway_Homo sapiens_hsa049151.07354851
48Axon guidance_Homo sapiens_hsa043601.02775337
49Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.02142812
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01321347
51VEGF signaling pathway_Homo sapiens_hsa043701.01068231
52B cell receptor signaling pathway_Homo sapiens_hsa046620.98293223
53Dorso-ventral axis formation_Homo sapiens_hsa043200.96324918
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.96119907
55Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.95203105
56Choline metabolism in cancer_Homo sapiens_hsa052310.90823234
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.90406019
58Carbohydrate digestion and absorption_Homo sapiens_hsa049730.88079941
59Intestinal immune network for IgA production_Homo sapiens_hsa046720.85483280
60Neurotrophin signaling pathway_Homo sapiens_hsa047220.85048229
61Chemokine signaling pathway_Homo sapiens_hsa040620.84974117
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83138105
63MAPK signaling pathway_Homo sapiens_hsa040100.82116947
64Melanogenesis_Homo sapiens_hsa049160.81982986
65Vitamin B6 metabolism_Homo sapiens_hsa007500.81754286
66Sphingolipid signaling pathway_Homo sapiens_hsa040710.81741317
67Non-small cell lung cancer_Homo sapiens_hsa052230.81039262
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.80822241
69Collecting duct acid secretion_Homo sapiens_hsa049660.80171731
70T cell receptor signaling pathway_Homo sapiens_hsa046600.79641219
71Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79414482
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.79242504
73Endocytosis_Homo sapiens_hsa041440.78484695
74Inositol phosphate metabolism_Homo sapiens_hsa005620.74352137
75Rheumatoid arthritis_Homo sapiens_hsa053230.72607701
76ABC transporters_Homo sapiens_hsa020100.71708492
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.70451246
78Thyroid hormone synthesis_Homo sapiens_hsa049180.69486258
79Jak-STAT signaling pathway_Homo sapiens_hsa046300.68201757
80Toll-like receptor signaling pathway_Homo sapiens_hsa046200.67192706
81Ras signaling pathway_Homo sapiens_hsa040140.65992993
82Rap1 signaling pathway_Homo sapiens_hsa040150.64772370
83Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63644993
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.63270315
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63147688
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61835498
87Hematopoietic cell lineage_Homo sapiens_hsa046400.61487742
88Ether lipid metabolism_Homo sapiens_hsa005650.61175735
89African trypanosomiasis_Homo sapiens_hsa051430.60476412
90Phagosome_Homo sapiens_hsa041450.59251368
91Measles_Homo sapiens_hsa051620.58693504
92Renal cell carcinoma_Homo sapiens_hsa052110.58521398
93Vibrio cholerae infection_Homo sapiens_hsa051100.58067339
94Oocyte meiosis_Homo sapiens_hsa041140.57667526
95Platelet activation_Homo sapiens_hsa046110.57023985
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54353732
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53230900
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52875998
99Asthma_Homo sapiens_hsa053100.51668886
100Type I diabetes mellitus_Homo sapiens_hsa049400.49297526
101Prolactin signaling pathway_Homo sapiens_hsa049170.48919827
102Prion diseases_Homo sapiens_hsa050200.48276725
103Osteoclast differentiation_Homo sapiens_hsa043800.48223413
104Mineral absorption_Homo sapiens_hsa049780.43902220
105Antigen processing and presentation_Homo sapiens_hsa046120.42142646
106mTOR signaling pathway_Homo sapiens_hsa041500.42006995
107Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41807098
108Primary immunodeficiency_Homo sapiens_hsa053400.40864395
109Bile secretion_Homo sapiens_hsa049760.40580387
110Glycerophospholipid metabolism_Homo sapiens_hsa005640.39623581
111Glucagon signaling pathway_Homo sapiens_hsa049220.39118726
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37591935
113SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33939139
114Alcoholism_Homo sapiens_hsa050340.33894470
115Dilated cardiomyopathy_Homo sapiens_hsa054140.33082824
116Tuberculosis_Homo sapiens_hsa051520.29991787
117Lysosome_Homo sapiens_hsa041420.29723619
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29114296
119Phototransduction_Homo sapiens_hsa047440.28998183
120Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.26029926
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.25610588
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.25506698
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25214117

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