MAML3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1doxorubicin metabolic process (GO:0044598)4.82302185
2daunorubicin metabolic process (GO:0044597)4.82302185
3polyketide metabolic process (GO:0030638)4.82302185
4embryonic camera-type eye morphogenesis (GO:0048596)4.34188908
5dosage compensation (GO:0007549)4.19839337
6pyrimidine nucleobase catabolic process (GO:0006208)4.16973513
7prostate gland growth (GO:0060736)4.09518901
8lymphoid progenitor cell differentiation (GO:0002320)3.74086821
9microtubule nucleation (GO:0007020)3.48579789
10sympathetic nervous system development (GO:0048485)3.45652491
11behavioral response to nicotine (GO:0035095)3.37677882
12histone H3-K4 trimethylation (GO:0080182)3.33605694
13regulation of DNA endoreduplication (GO:0032875)3.33378962
14embryonic eye morphogenesis (GO:0048048)3.24263526
15cardiac ventricle formation (GO:0003211)3.22194795
16positive regulation of gastrulation (GO:2000543)3.19201077
17nucleobase catabolic process (GO:0046113)3.18495985
18ganglion development (GO:0061548)3.18406774
19auditory receptor cell differentiation (GO:0042491)3.18379661
20positive regulation of mast cell activation (GO:0033005)3.14238704
21negative regulation of translation, ncRNA-mediated (GO:0040033)3.13178823
22regulation of translation, ncRNA-mediated (GO:0045974)3.13178823
23negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.13178823
24myeloid leukocyte mediated immunity (GO:0002444)3.12365786
25mesenchymal cell differentiation (GO:0048762)3.12191003
26positive regulation by symbiont of host defense response (GO:0052509)3.10586159
27modulation by symbiont of host defense response (GO:0052031)3.10586159
28modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.10586159
29modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.10586159
30positive regulation by organism of defense response of other organism involved in symbiotic interact3.10586159
31modulation by symbiont of host immune response (GO:0052553)3.10586159
32activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)3.10485247
33post-anal tail morphogenesis (GO:0036342)3.08349789
34cell migration in hindbrain (GO:0021535)3.05303843
35energy homeostasis (GO:0097009)3.05219050
36dendritic spine morphogenesis (GO:0060997)3.05114269
37cardiac chamber formation (GO:0003207)3.04128833
38neutrophil activation involved in immune response (GO:0002283)3.03326536
39regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.03198622
40regulation of mitochondrial translation (GO:0070129)2.99385198
41epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.98534012
42poly(A)+ mRNA export from nucleus (GO:0016973)2.97360005
43somite development (GO:0061053)2.92523359
44type B pancreatic cell development (GO:0003323)2.92359959
45paraxial mesoderm development (GO:0048339)2.90552762
46embryonic retina morphogenesis in camera-type eye (GO:0060059)2.90517222
47thrombin receptor signaling pathway (GO:0070493)2.90274432
48artery development (GO:0060840)2.88331540
49exocrine pancreas development (GO:0031017)2.88124082
50regulation of somitogenesis (GO:0014807)2.86061998
51regulation of mesenchymal cell apoptotic process (GO:2001053)2.83702197
52cytoplasmic mRNA processing body assembly (GO:0033962)2.83505462
53cornea development in camera-type eye (GO:0061303)2.80821556
54positive regulation of interleukin-1 beta secretion (GO:0050718)2.78842686
55limb bud formation (GO:0060174)2.78065558
56histone H3-K36 demethylation (GO:0070544)2.77778254
57spinal cord association neuron differentiation (GO:0021527)2.77091924
58olfactory bulb development (GO:0021772)2.76997698
59dopaminergic neuron differentiation (GO:0071542)2.76305557
60neural tube formation (GO:0001841)2.76120946
61positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.75601964
62negative regulation of stem cell proliferation (GO:2000647)2.72915000
63cellular extravasation (GO:0045123)2.72407051
64aminoglycoside antibiotic metabolic process (GO:0030647)2.69311106
65mesenchymal cell differentiation involved in kidney development (GO:0072161)2.68180194
66mesenchymal cell differentiation involved in renal system development (GO:2001012)2.68180194
67histone lysine demethylation (GO:0070076)2.66342264
68axonal fasciculation (GO:0007413)2.65608404
69kidney morphogenesis (GO:0060993)2.65260955
70neutrophil activation (GO:0042119)2.64330785
71glandular epithelial cell development (GO:0002068)2.63535245
72definitive hemopoiesis (GO:0060216)2.62957181
73cell differentiation in spinal cord (GO:0021515)2.62108893
74phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.61615390
75central nervous system projection neuron axonogenesis (GO:0021952)2.60584122
76synapse assembly (GO:0007416)2.58777365
77cranial nerve morphogenesis (GO:0021602)2.56997703
78leukocyte migration involved in inflammatory response (GO:0002523)2.56325570
79microglial cell activation (GO:0001774)2.56298353
80protein-DNA complex disassembly (GO:0032986)2.55942796
81nucleosome disassembly (GO:0006337)2.55942796
82activated T cell proliferation (GO:0050798)2.55409215
83central nervous system neuron axonogenesis (GO:0021955)2.55059546
84positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.54415931
85mesenchymal to epithelial transition (GO:0060231)2.53785952
86negative regulation of glial cell proliferation (GO:0060253)2.52798914
87macrophage activation involved in immune response (GO:0002281)2.52642653
88negative regulation of erythrocyte differentiation (GO:0045647)2.52610514
89response to peptidoglycan (GO:0032494)2.52434423
90cell differentiation involved in metanephros development (GO:0072202)2.52273246
91histone demethylation (GO:0016577)2.51408270
92neutrophil mediated immunity (GO:0002446)2.51218817
93positive regulation of interleukin-1 secretion (GO:0050716)2.50179761
94positive regulation of mast cell activation involved in immune response (GO:0033008)2.48920755
95positive regulation of mast cell degranulation (GO:0043306)2.48920755
96detection of molecule of bacterial origin (GO:0032490)2.47490460
97head development (GO:0060322)2.47311673
98response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.47158534
99response to host immune response (GO:0052572)2.47158534
100negative regulation of neurotransmitter secretion (GO:0046929)2.46800403
101dentate gyrus development (GO:0021542)2.43782337
102interkinetic nuclear migration (GO:0022027)2.42279263
103developmental pigmentation (GO:0048066)2.42277159
104coronary vasculature morphogenesis (GO:0060977)2.41547010
105bone remodeling (GO:0046849)2.40772219
106neuron maturation (GO:0042551)2.40045862
107centriole assembly (GO:0098534)2.38891603
108retrograde transport, vesicle recycling within Golgi (GO:0000301)2.36035452
109auditory behavior (GO:0031223)2.35558999
110cell differentiation in hindbrain (GO:0021533)2.35274643
111cranial nerve development (GO:0021545)2.35124025
112negative regulation of osteoblast proliferation (GO:0033689)2.35010396
113pharyngeal system development (GO:0060037)2.35002933
114regulation of MHC class II biosynthetic process (GO:0045346)2.34611268
115response to pheromone (GO:0019236)2.34588584
116neural crest cell development (GO:0014032)2.33606695
117behavioral response to ethanol (GO:0048149)2.33523397
118retinal ganglion cell axon guidance (GO:0031290)2.33172914
119replicative senescence (GO:0090399)2.32700992
120negative regulation of alpha-beta T cell differentiation (GO:0046639)2.32235115
121DNA integration (GO:0015074)2.31306277
122appendage development (GO:0048736)2.29687100
123limb development (GO:0060173)2.29687100
124regulation of chromatin binding (GO:0035561)2.29672411
125peptidyl-lysine trimethylation (GO:0018023)2.29621557
126cerebellar Purkinje cell differentiation (GO:0021702)2.29150182
127positive regulation of interleukin-1 beta production (GO:0032731)2.28360585
128male sex determination (GO:0030238)2.27727112
129macrophage activation (GO:0042116)2.27625188
130dendritic cell migration (GO:0036336)2.27507772
131centriole replication (GO:0007099)2.27257964
132mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.27009812
133negative regulation of neurotransmitter transport (GO:0051589)2.26279764
134negative regulation of T-helper cell differentiation (GO:0045623)2.26021935
135negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.26021935
136neuron recognition (GO:0008038)2.25188733
137regulation of histone H3-K4 methylation (GO:0051569)2.24749939
138negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.23721058
139cell proliferation involved in kidney development (GO:0072111)2.23550202
140branching involved in mammary gland duct morphogenesis (GO:0060444)2.23504302
141microtubule anchoring (GO:0034453)2.23498799
142regulation of mast cell activation (GO:0033003)2.22549507
143columnar/cuboidal epithelial cell development (GO:0002066)2.21981060
144positive regulation of DNA-dependent DNA replication (GO:2000105)2.21412619
145trophoblast giant cell differentiation (GO:0060707)2.20980755
146gastrulation with mouth forming second (GO:0001702)2.20826931
147mesenchyme morphogenesis (GO:0072132)2.20424232
148glandular epithelial cell differentiation (GO:0002067)2.20366533
149embryonic hemopoiesis (GO:0035162)2.20167617
150negative regulation of transcription regulatory region DNA binding (GO:2000678)2.19386250
151histone H3-K4 methylation (GO:0051568)2.19238156
152regulation of cardioblast proliferation (GO:0003264)2.19039157
153regulation of secondary heart field cardioblast proliferation (GO:0003266)2.19039157
154cell proliferation in forebrain (GO:0021846)2.18932332
155negative regulation of myoblast differentiation (GO:0045662)2.18520852
156G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.18107970
157positive regulation of histone H3-K4 methylation (GO:0051571)2.17861383
158osteoblast development (GO:0002076)2.17812362
159regulation of interleukin-1 beta secretion (GO:0050706)2.17358717
160epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.16860374
161specification of organ identity (GO:0010092)2.16790105
162nerve growth factor signaling pathway (GO:0038180)2.16769962
163response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.16222767
164response to host (GO:0075136)2.16222767
165response to host defenses (GO:0052200)2.16222767
166hindbrain development (GO:0030902)2.15896904
167negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.15676191
168signal transduction involved in regulation of gene expression (GO:0023019)2.15619828
169ear development (GO:0043583)2.15064026
170granulocyte activation (GO:0036230)2.14653730
171glomerulus development (GO:0032835)2.14559137
172regulation of interleukin-6 biosynthetic process (GO:0045408)2.14281852
173endothelium development (GO:0003158)2.14094022
174primitive streak formation (GO:0090009)2.13645034
175regulation of non-canonical Wnt signaling pathway (GO:2000050)2.13406234
176positive regulation of granulocyte differentiation (GO:0030854)2.12992710
177epithelial cell maturation (GO:0002070)2.12479194
178histamine secretion (GO:0001821)2.12382090
179face development (GO:0060324)2.11981368
180dorsal/ventral neural tube patterning (GO:0021904)2.11821147
181epithelial cell fate commitment (GO:0072148)2.11707852
182regulation of erythrocyte differentiation (GO:0045646)2.10609097
183histone H3-K9 demethylation (GO:0033169)2.10523052
184protein demethylation (GO:0006482)2.09998206
185protein dealkylation (GO:0008214)2.09998206
186negative chemotaxis (GO:0050919)2.09449544
187histone H3-K9 methylation (GO:0051567)2.09357326

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_19390658_ChIP-ChIP_HaCaT_Human4.04278637
2EZH2_22144423_ChIP-Seq_EOC_Human2.74391505
3* SCL_19346495_ChIP-Seq_HPC-7_Human2.54421868
4IGF1R_20145208_ChIP-Seq_DFB_Human2.53834795
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.48088693
6* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.47067946
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.46654642
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.36382549
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.13688282
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.13205867
11STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.07541812
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.07055127
13* CBX2_27304074_Chip-Seq_ESCs_Mouse2.06660440
14TP63_17297297_ChIP-ChIP_HaCaT_Human2.00778134
15EED_16625203_ChIP-ChIP_MESCs_Mouse1.99625523
16EGR1_19374776_ChIP-ChIP_THP-1_Human1.98278012
17GBX2_23144817_ChIP-Seq_PC3_Human1.91460401
18* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.90249863
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.84657573
20PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.84549368
21PCGF2_27294783_Chip-Seq_NPCs_Mouse1.84206123
22* EZH2_27304074_Chip-Seq_ESCs_Mouse1.83271771
23BP1_19119308_ChIP-ChIP_Hs578T_Human1.78817901
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.78297216
25RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.78236477
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77834743
27POU5F1_16153702_ChIP-ChIP_HESCs_Human1.76396132
28* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.69302095
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.67251921
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.65525690
31REST_21632747_ChIP-Seq_MESCs_Mouse1.64831271
32GATA1_22025678_ChIP-Seq_K562_Human1.63289359
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.60478468
34DROSHA_22980978_ChIP-Seq_HELA_Human1.60082309
35SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.59784278
36* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.59593584
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.57768153
38RNF2_27304074_Chip-Seq_NSC_Mouse1.57113021
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.55809537
40* RNF2_27304074_Chip-Seq_ESCs_Mouse1.55471099
41SMAD_19615063_ChIP-ChIP_OVARY_Human1.55136583
42* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.52828649
43* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.52328340
44SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.51480079
45* NANOG_18555785_Chip-Seq_ESCs_Mouse1.50691672
46* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49923086
47EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.48781805
48* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44325478
49SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.42366431
50E2F7_22180533_ChIP-Seq_HELA_Human1.41863650
51VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.41494150
52STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.40664409
53* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.40462787
54NFE2_27457419_Chip-Seq_LIVER_Mouse1.39270311
55CDX2_20551321_ChIP-Seq_CACO-2_Human1.38872266
56TAF15_26573619_Chip-Seq_HEK293_Human1.38625705
57AR_21572438_ChIP-Seq_LNCaP_Human1.38396493
58* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.37932284
59VDR_22108803_ChIP-Seq_LS180_Human1.37768401
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.36881497
61AHR_22903824_ChIP-Seq_MCF-7_Human1.34536637
62* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.34467949
63* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.34357247
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.32753643
65* P300_19829295_ChIP-Seq_ESCs_Human1.31982890
66* E2F1_18555785_Chip-Seq_ESCs_Mouse1.31177846
67SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.30564622
68NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.30382339
69EZH2_27294783_Chip-Seq_NPCs_Mouse1.30222289
70RNF2_18974828_ChIP-Seq_MESCs_Mouse1.29268739
71EZH2_18974828_ChIP-Seq_MESCs_Mouse1.29268739
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28328150
73SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.27547828
74ARNT_22903824_ChIP-Seq_MCF-7_Human1.26919511
75CDX2_19796622_ChIP-Seq_MESCs_Mouse1.26142505
76MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25873526
77* RUNX2_22187159_ChIP-Seq_PCA_Human1.25223232
78POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.24820797
79TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24820797
80NR3C1_21868756_ChIP-Seq_MCF10A_Human1.24590223
81BCAT_22108803_ChIP-Seq_LS180_Human1.24262373
82WT1_19549856_ChIP-ChIP_CCG9911_Human1.23331475
83SUZ12_18555785_Chip-Seq_ESCs_Mouse1.23300694
84SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.22911136
85* EZH2_27294783_Chip-Seq_ESCs_Mouse1.22883502
86* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.22639213
87* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.22582055
88VDR_24787735_ChIP-Seq_THP-1_Human1.21956633
89* P53_22387025_ChIP-Seq_ESCs_Mouse1.21808322
90* AR_25329375_ChIP-Seq_VCAP_Human1.21691045
91RING1B_27294783_Chip-Seq_NPCs_Mouse1.20488606
92* CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.20222913
93TP53_18474530_ChIP-ChIP_U2OS_Human1.19684014
94* ISL1_27105846_Chip-Seq_CPCs_Mouse1.19013667
95* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.18178774
96HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.17602648
97SALL1_21062744_ChIP-ChIP_HESCs_Human1.17420741
98NMYC_18555785_Chip-Seq_ESCs_Mouse1.17280831
99ER_23166858_ChIP-Seq_MCF-7_Human1.17055722
100* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.15276551
101* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15217737
102SMAD4_21799915_ChIP-Seq_A2780_Human1.15182541
103* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15054538
104* STAT3_18555785_Chip-Seq_ESCs_Mouse1.13804720
105* SMAD3_21741376_ChIP-Seq_EPCs_Human1.13504602
106* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12888703
107ZNF274_21170338_ChIP-Seq_K562_Hela1.12479616
108SPI1_23127762_ChIP-Seq_K562_Human1.11913276
109ELF1_17652178_ChIP-ChIP_JURKAT_Human1.11498709
110EWS_26573619_Chip-Seq_HEK293_Human1.11004517
111* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10137214
112STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.09557231
113* RING1B_27294783_Chip-Seq_ESCs_Mouse1.09396914
114EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09311327
115* STAT3_23295773_ChIP-Seq_U87_Human1.08651421
116* ZFX_18555785_Chip-Seq_ESCs_Mouse1.08377183
117BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.08056035
118OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07291820
119REST_18959480_ChIP-ChIP_MESCs_Mouse1.06503426
120DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06501685
121TCF4_23295773_ChIP-Seq_U87_Human1.04889810
122* CMYC_18555785_Chip-Seq_ESCs_Mouse1.04685393
123TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04430852
124SMAD3_21741376_ChIP-Seq_HESCs_Human1.04388712
125MTF2_20144788_ChIP-Seq_MESCs_Mouse1.04187653
126EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04132904
127IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.02915871
128* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01410920
129CTBP1_25329375_ChIP-Seq_LNCAP_Human1.01259794
130OCT4_18555785_Chip-Seq_ESCs_Mouse1.01080416
131* GATA1_19941827_ChIP-Seq_MEL_Mouse1.00846013
132* SOX2_21211035_ChIP-Seq_LN229_Gbm0.99333243
133* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98601679
134OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98448939
135* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.97924503
136VDR_24763502_ChIP-Seq_THP-1_Human0.96945448
137KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.96692889
138* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96137624
139* FOXA1_25552417_ChIP-Seq_VCAP_Human0.95457028
140CTBP2_25329375_ChIP-Seq_LNCAP_Human0.95013203
141* AR_19668381_ChIP-Seq_PC3_Human0.94901181
142ELK4_26923725_Chip-Seq_MESODERM_Mouse0.94389190
143SMAD4_21741376_ChIP-Seq_HESCs_Human0.94104037
144TCF4_18268006_ChIP-ChIP_LS174T_Human0.93342779
145PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92991727
146GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91536187
147Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.90875186

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy5.66583783
2MP0000566_synostosis4.72799258
3MP0003787_abnormal_imprinting4.69632724
4MP0001346_abnormal_lacrimal_gland3.37124105
5MP0005645_abnormal_hypothalamus_physiol2.94078115
6MP0005379_endocrine/exocrine_gland_phen2.82700011
7MP0003941_abnormal_skin_development2.58464096
8MP0003283_abnormal_digestive_organ2.56790660
9MP0003121_genomic_imprinting2.50502219
10MP0006292_abnormal_olfactory_placode2.48152394
11MP0003724_increased_susceptibility_to2.44001445
12MP0010386_abnormal_urinary_bladder2.43508135
13MP0002938_white_spotting2.40114816
14MP0002909_abnormal_adrenal_gland2.16862026
15MP0005464_abnormal_platelet_physiology2.15117874
16MP0002396_abnormal_hematopoietic_system2.13709078
17MP0005257_abnormal_intraocular_pressure2.08502383
18MP0005248_abnormal_Harderian_gland1.92800499
19MP0002653_abnormal_ependyma_morphology1.89965401
20MP0000778_abnormal_nervous_system1.88610854
21MP0004264_abnormal_extraembryonic_tissu1.85979054
22MP0001188_hyperpigmentation1.84920429
23MP0002638_abnormal_pupillary_reflex1.84832703
24MP0003122_maternal_imprinting1.84339582
25MP0002735_abnormal_chemical_nociception1.80945503
26MP0004145_abnormal_muscle_electrophysio1.77619080
27MP0003828_pulmonary_edema1.73196284
28MP0009697_abnormal_copulation1.71285167
29MP0003303_peritoneal_inflammation1.69844287
30MP0002163_abnormal_gland_morphology1.61213400
31MP0000569_abnormal_digit_pigmentation1.59680467
32MP0003011_delayed_dark_adaptation1.59237787
33MP0005646_abnormal_pituitary_gland1.58139903
34MP0003183_abnormal_peptide_metabolism1.56337965
35MP0002277_abnormal_respiratory_mucosa1.56051075
36MP0005174_abnormal_tail_pigmentation1.55960599
37MP0008789_abnormal_olfactory_epithelium1.51882213
38MP0000678_abnormal_parathyroid_gland1.43695565
39MP0009278_abnormal_bone_marrow1.42038454
40MP0002693_abnormal_pancreas_physiology1.41929516
41MP0002095_abnormal_skin_pigmentation1.41866853
42MP0000049_abnormal_middle_ear1.38967712
43MP0005167_abnormal_blood-brain_barrier1.38184920
44MP0002132_abnormal_respiratory_system1.37059584
45MP0001944_abnormal_pancreas_morphology1.36568147
46MP0002098_abnormal_vibrissa_morphology1.36476240
47MP0008961_abnormal_basal_metabolism1.36351486
48MP0008058_abnormal_DNA_repair1.35864884
49MP0005503_abnormal_tendon_morphology1.34343069
50MP0002751_abnormal_autonomic_nervous1.34244754
51MP0004133_heterotaxia1.32536014
52MP0001879_abnormal_lymphatic_vessel1.32251591
53MP0002733_abnormal_thermal_nociception1.29938138
54MP0002177_abnormal_outer_ear1.28742472
55MP0004808_abnormal_hematopoietic_stem1.28579234
56MP0008004_abnormal_stomach_pH1.28297631
57MP0002184_abnormal_innervation1.26260191
58MP0000427_abnormal_hair_cycle1.26211074
59MP0010030_abnormal_orbit_morphology1.24966837
60MP0000631_abnormal_neuroendocrine_gland1.24624808
61MP0001970_abnormal_pain_threshold1.24287309
62MP0005220_abnormal_exocrine_pancreas1.24054104
63MP0002009_preneoplasia1.20744612
64MP0008995_early_reproductive_senescence1.20700384
65MP0000681_abnormal_thyroid_gland1.19119701
66MP0005171_absent_coat_pigmentation1.18359386
67MP0001986_abnormal_taste_sensitivity1.17660029
68MP0003123_paternal_imprinting1.16580439
69MP0003172_abnormal_lysosome_physiology1.15425464
70MP0005409_darkened_coat_color1.14637113
71MP0003385_abnormal_body_wall1.14511421
72MP0000955_abnormal_spinal_cord1.13757868
73MP0001293_anophthalmia1.11983437
74MP0000537_abnormal_urethra_morphology1.10921565
75MP0004130_abnormal_muscle_cell1.09699328
76MP0002166_altered_tumor_susceptibility1.06501678
77MP0005397_hematopoietic_system_phenotyp1.03560524
78MP0001545_abnormal_hematopoietic_system1.03560524
79MP0002233_abnormal_nose_morphology1.03423577
80MP0000015_abnormal_ear_pigmentation1.03237478
81MP0000230_abnormal_systemic_arterial1.03146732
82MP0005423_abnormal_somatic_nervous1.02114892
83MP0003937_abnormal_limbs/digits/tail_de1.01568679
84MP0000538_abnormal_urinary_bladder1.01548855
85MP0001286_abnormal_eye_development1.00901084
86MP0002116_abnormal_craniofacial_bone0.99668014
87MP0005448_abnormal_energy_balance0.97876333
88MP0002928_abnormal_bile_duct0.97748746
89MP0005647_abnormal_sex_gland0.97198125
90MP0003935_abnormal_craniofacial_develop0.96854175
91MP0000383_abnormal_hair_follicle0.96044135
92MP0005310_abnormal_salivary_gland0.95448786
93MP0005394_taste/olfaction_phenotype0.94839178
94MP0005499_abnormal_olfactory_system0.94839178
95MP0002734_abnormal_mechanical_nocicepti0.94007869
96MP0008007_abnormal_cellular_replicative0.93729384
97MP0002063_abnormal_learning/memory/cond0.93342751
98MP0003880_abnormal_central_pattern0.93065734
99MP0001270_distended_abdomen0.92984622
100MP0002102_abnormal_ear_morphology0.92395258
101MP0003635_abnormal_synaptic_transmissio0.91742524
102MP0002572_abnormal_emotion/affect_behav0.91217212
103MP0003943_abnormal_hepatobiliary_system0.90591525
104MP0004811_abnormal_neuron_physiology0.89595775
105MP0001486_abnormal_startle_reflex0.88987731
106MP0002109_abnormal_limb_morphology0.88600523
107MP0005386_behavior/neurological_phenoty0.88107146
108MP0004924_abnormal_behavior0.88107146
109MP0008877_abnormal_DNA_methylation0.87795620
110MP0005076_abnormal_cell_differentiation0.87774775
111MP0002127_abnormal_cardiovascular_syste0.86262234
112MP0002113_abnormal_skeleton_development0.86070774
113MP0003942_abnormal_urinary_system0.84804357
114MP0001919_abnormal_reproductive_system0.83845651
115MP0004272_abnormal_basement_membrane0.83176972
116MP0003890_abnormal_embryonic-extraembry0.83128943
117MP0002882_abnormal_neuron_morphology0.82961403
118MP0000470_abnormal_stomach_morphology0.82923356
119MP0001324_abnormal_eye_pigmentation0.82804422
120MP0004381_abnormal_hair_follicle0.82505684
121MP0010368_abnormal_lymphatic_system0.80966594
122MP0004270_analgesia0.80829816
123MP0005075_abnormal_melanosome_morpholog0.79806424
124MP0003938_abnormal_ear_development0.78777910
125MP0002152_abnormal_brain_morphology0.78492460
126MP0002697_abnormal_eye_size0.76833633
127MP0002896_abnormal_bone_mineralization0.76765561
128MP0002557_abnormal_social/conspecific_i0.76323754
129MP0003755_abnormal_palate_morphology0.75764216
130MP0001186_pigmentation_phenotype0.75235302
131MP0002249_abnormal_larynx_morphology0.75070479
132MP0005508_abnormal_skeleton_morphology0.74813580
133MP0003861_abnormal_nervous_system0.74146369
134MP0001905_abnormal_dopamine_level0.73720512
135MP0002876_abnormal_thyroid_physiology0.73332124
136MP0005535_abnormal_body_temperature0.73208888
137MP0000613_abnormal_salivary_gland0.72878909
138MP0004510_myositis0.72751715
139MP0009250_abnormal_appendicular_skeleto0.72698257
140MP0003948_abnormal_gas_homeostasis0.72586513
141MP0005197_abnormal_uvea_morphology0.71997388
142MP0002752_abnormal_somatic_nervous0.71764859
143MP0004085_abnormal_heartbeat0.71585608
144MP0002069_abnormal_eating/drinking_beha0.71127276
145MP0006276_abnormal_autonomic_nervous0.70753496
146MP0001765_abnormal_ion_homeostasis0.70689965
147MP0002932_abnormal_joint_morphology0.70524984
148MP0002111_abnormal_tail_morphology0.70507355
149MP0001485_abnormal_pinna_reflex0.69877350
150MP0003045_fibrosis0.68847335
151MP0005367_renal/urinary_system_phenotyp0.67630215
152MP0000516_abnormal_urinary_system0.67630215
153MP0005671_abnormal_response_to0.66825887
154MP0001968_abnormal_touch/_nociception0.66766456
155MP0000465_gastrointestinal_hemorrhage0.66519216
156MP0003315_abnormal_perineum_morphology0.65384307
157MP0000163_abnormal_cartilage_morphology0.64705961
158MP0002075_abnormal_coat/hair_pigmentati0.64702492
159MP0000858_altered_metastatic_potential0.63408764
160MP0001119_abnormal_female_reproductive0.62952968
161MP0004782_abnormal_surfactant_physiolog0.61804175

Predicted human phenotypes

RankGene SetZ-score
1Neonatal hypoglycemia (HP:0001998)4.57073055
2Genetic anticipation (HP:0003743)3.66091961
3Agitation (HP:0000713)3.64673930
4Abnormality of the intervertebral disk (HP:0005108)3.55298813
5Aplasia cutis congenita (HP:0001057)3.28612511
6Truncal obesity (HP:0001956)3.17726263
7Hypothermia (HP:0002045)3.14331181
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.08796780
9Chromsome breakage (HP:0040012)2.93870214
10Abnormality of the aortic arch (HP:0012303)2.86618483
11Insulin-resistant diabetes mellitus (HP:0000831)2.79196831
12Sparse scalp hair (HP:0002209)2.73711149
13Gingival bleeding (HP:0000225)2.70934956
14Abnormal platelet volume (HP:0011876)2.63565520
15Abnormality of incisor morphology (HP:0011063)2.57736676
16Hypochromic microcytic anemia (HP:0004840)2.56967842
17Spontaneous hematomas (HP:0007420)2.55904868
18Increased mean platelet volume (HP:0011877)2.54911902
19Papillary thyroid carcinoma (HP:0002895)2.52912785
20Unilateral renal agenesis (HP:0000122)2.51264281
21Intestinal atresia (HP:0011100)2.49324647
22Anal stenosis (HP:0002025)2.46988377
23Abnormality of the nasal septum (HP:0000419)2.45006935
24Progressive cerebellar ataxia (HP:0002073)2.44731267
25Chronic hepatic failure (HP:0100626)2.44683396
26Testicular neoplasm (HP:0010788)2.44342303
27Absent speech (HP:0001344)2.43790926
28Absent eyebrow (HP:0002223)2.43309142
29Epistaxis (HP:0000421)2.42104826
30Petechiae (HP:0000967)2.39365361
31Abnormality of the parietal bone (HP:0002696)2.36989423
32Abnormal hair whorl (HP:0010721)2.31227282
33Neoplasm of the adrenal cortex (HP:0100641)2.30886966
34Hyperventilation (HP:0002883)2.30428153
35Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.26861438
36Short 4th metacarpal (HP:0010044)2.26861438
37White forelock (HP:0002211)2.24265207
38Cheilitis (HP:0100825)2.23935936
39Drooling (HP:0002307)2.23389451
40Abnormal pancreas size (HP:0012094)2.22302857
41Abnormality of the parathyroid morphology (HP:0011766)2.22134413
42Germ cell neoplasia (HP:0100728)2.20639021
43Failure to thrive in infancy (HP:0001531)2.20128933
44Osteomalacia (HP:0002749)2.19076082
45Decreased circulating renin level (HP:0003351)2.18587568
46Abnormality of the incisor (HP:0000676)2.17945965
47Growth hormone deficiency (HP:0000824)2.17070281
48Abnormality of the fingertips (HP:0001211)2.17027860
49Thyroid carcinoma (HP:0002890)2.16449775
50Gonadotropin excess (HP:0000837)2.16253821
51Excessive salivation (HP:0003781)2.14984869
52Abnormality of the 1st metacarpal (HP:0010009)2.14856263
53Lip pit (HP:0100267)2.14575960
54Reticulocytopenia (HP:0001896)2.13446858
55Overgrowth (HP:0001548)2.13348637
56Pendular nystagmus (HP:0012043)2.11900133
57Patchy hypopigmentation of hair (HP:0011365)2.10525861
58Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.09482370
59Short 1st metacarpal (HP:0010034)2.09482370
60Congenital sensorineural hearing impairment (HP:0008527)2.06554487
61Abnormality of calcium-phosphate metabolism (HP:0100530)2.02895659
62Abnormality of the right ventricle (HP:0001707)2.02034730
63Nephronophthisis (HP:0000090)1.99589201
64Patellar aplasia (HP:0006443)1.99200752
65Menstrual irregularities (HP:0000858)1.98485416
66Curly hair (HP:0002212)1.97949389
67Deep palmar crease (HP:0006191)1.95396988
68Diastasis recti (HP:0001540)1.94055285
69Slow-growing hair (HP:0002217)1.93625848
70Abnormality of hair growth rate (HP:0011363)1.93625848
71Thyroiditis (HP:0100646)1.92440273
72Hip dysplasia (HP:0001385)1.90770690
73True hermaphroditism (HP:0010459)1.88106686
74Gaze-evoked nystagmus (HP:0000640)1.87461015
75Widely spaced teeth (HP:0000687)1.87001979
76Aqueductal stenosis (HP:0002410)1.85419377
77Obsessive-compulsive behavior (HP:0000722)1.85208836
78Macroorchidism (HP:0000053)1.84720101
79Sporadic (HP:0003745)1.83875540
80Cystic liver disease (HP:0006706)1.83653421
81Abnormality of the axillary hair (HP:0100134)1.81876528
82Abnormality of secondary sexual hair (HP:0009888)1.81876528
83Acute lymphatic leukemia (HP:0006721)1.80906481
84Short phalanx of the thumb (HP:0009660)1.80875161
85Narrow palate (HP:0000189)1.80378545
86Elfin facies (HP:0004428)1.80218024
87Aplasia/Hypoplasia of the patella (HP:0006498)1.78747802
88Shawl scrotum (HP:0000049)1.78647104
89Long eyelashes (HP:0000527)1.77456093
90Spina bifida occulta (HP:0003298)1.76758544
91Laryngomalacia (HP:0001601)1.76554828
92Thick eyebrow (HP:0000574)1.76367139
93Purpura (HP:0000979)1.75679138
94Tubulointerstitial nephritis (HP:0001970)1.74668736
95Protruding tongue (HP:0010808)1.73826035
96Cutaneous finger syndactyly (HP:0010554)1.73029587
97Midline defect of the nose (HP:0004122)1.72937824
98Cranial hyperostosis (HP:0004437)1.72886595
99Chin dimple (HP:0010751)1.72883915
100Abnormality of the renal medulla (HP:0100957)1.71921799
101Abnormal number of incisors (HP:0011064)1.71787313
102Craniofacial hyperostosis (HP:0004493)1.69825988
103Renal dysplasia (HP:0000110)1.69624145
104Ectopic kidney (HP:0000086)1.69446812
105Hypoplastic iliac wings (HP:0002866)1.69394497
106Tapered finger (HP:0001182)1.69194333
107Eczematoid dermatitis (HP:0000976)1.68632557
108Abnormality of the 4th metacarpal (HP:0010012)1.67757254
109Hypoplastic labia majora (HP:0000059)1.67752751
110Absent/shortened dynein arms (HP:0200106)1.66893153
111Dynein arm defect of respiratory motile cilia (HP:0012255)1.66893153
112Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.66398546
113Abnormality of the distal phalanx of the thumb (HP:0009617)1.66004822
114Prolonged bleeding time (HP:0003010)1.65518922
115Hyperglycemia (HP:0003074)1.63788869
116Volvulus (HP:0002580)1.63717027
117Symptomatic seizures (HP:0011145)1.63575339
118Abnormality of the renal collecting system (HP:0004742)1.62758318
119Recurrent bacterial skin infections (HP:0005406)1.62483080
120Atelectasis (HP:0100750)1.62107343
121Thickened calvaria (HP:0002684)1.61655871
122Recurrent corneal erosions (HP:0000495)1.60317274
123Cutaneous syndactyly (HP:0012725)1.60291310
124Prostate neoplasm (HP:0100787)1.59859967
125Polyphagia (HP:0002591)1.59820087
126Portal hypertension (HP:0001409)1.59074830
127Transitional cell carcinoma of the bladder (HP:0006740)1.59060332
128Stomatitis (HP:0010280)1.58508674
129Onycholysis (HP:0001806)1.58507740
130Anhidrosis (HP:0000970)1.58461359
131Oligodactyly (hands) (HP:0001180)1.56511970
132Hypoplastic ischia (HP:0003175)1.56132959
133Impaired smooth pursuit (HP:0007772)1.55592821
134Ectropion (HP:0000656)1.55525277
135Tented upper lip vermilion (HP:0010804)1.54864588
136Patellar dislocation (HP:0002999)1.54577815
137Long foot (HP:0001833)1.54320733
138Submucous cleft hard palate (HP:0000176)1.53872760
139Rib fusion (HP:0000902)1.53799568
140Neoplasm of the tracheobronchial system (HP:0100552)1.53669706
141Heterotopia (HP:0002282)1.53618199
142Amblyopia (HP:0000646)1.53607572
143Morphological abnormality of the middle ear (HP:0008609)1.53538494
144Renal duplication (HP:0000075)1.53503104
145Mask-like facies (HP:0000298)1.52564254
146Myokymia (HP:0002411)1.52523686
147Abnormality of the columella (HP:0009929)1.52511424
148Dry hair (HP:0011359)1.52075539
149Bladder neoplasm (HP:0009725)1.52065748
150Bladder carcinoma (HP:0002862)1.52065748
151Narrow forehead (HP:0000341)1.52059241
152Thickened helices (HP:0000391)1.51571414
153Long clavicles (HP:0000890)1.50424994
154Heterochromia iridis (HP:0001100)1.50121110
155Menorrhagia (HP:0000132)1.49205469
156Abnormality of the labia majora (HP:0012881)1.49179977
157Urethral obstruction (HP:0000796)1.49103794
158Hepatoblastoma (HP:0002884)1.48854266
159Aplasia/Hypoplasia of the earlobes (HP:0009906)1.47938700
160Popliteal pterygium (HP:0009756)1.46176687
161Exotropia (HP:0000577)1.45718439
162Duplication of thumb phalanx (HP:0009942)1.45329555
163Duplicated collecting system (HP:0000081)1.44306023
164Short philtrum (HP:0000322)1.43976370
165Barrel-shaped chest (HP:0001552)1.43636406
166Hypoglycemic seizures (HP:0002173)1.43039166
167Convex nasal ridge (HP:0000444)1.42778058
168Renovascular hypertension (HP:0100817)1.40566449
169Xerostomia (HP:0000217)1.40404204
170Pancreatic islet-cell hyperplasia (HP:0004510)1.40203464
171Optic nerve coloboma (HP:0000588)1.40199373
172Cutis marmorata (HP:0000965)1.39449120
173Renal hypoplasia (HP:0000089)1.39175227
174Ridged nail (HP:0001807)1.38606276

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR4.42986173
2ERBB33.37238180
3EPHA23.30101226
4ADRBK23.18812298
5SIK32.94490103
6PLK42.87840655
7CDK122.61386763
8BRD42.42024894
9TAOK12.36137958
10NUAK12.16900550
11ZAK2.04799330
12PASK2.03001885
13SRPK11.98828888
14SIK21.95907010
15CDK81.95461999
16IRAK41.89395606
17RIPK41.88580131
18FES1.85732669
19FER1.80782440
20LATS11.77908770
21YES11.73378287
22MARK11.70220737
23MAPK151.64818135
24MKNK21.59683956
25BMPR21.58177186
26SGK2231.53943159
27SGK4941.53943159
28TAOK31.52837508
29TNIK1.50088161
30KIT1.47846533
31TXK1.36605632
32HIPK21.34699916
33MAP2K41.33920734
34PRKD21.28053422
35FRK1.26040336
36WNK11.25070494
37PIK3CG1.24970371
38DAPK21.21087752
39TNK21.20948358
40MKNK11.20683129
41BMPR1B1.19390746
42MAP3K41.18612263
43EPHB21.13920221
44BLK1.13561275
45TEC1.11518125
46TGFBR21.07316260
47DYRK1B1.04380226
48PAK31.01862000
49VRK11.00436184
50CASK1.00209672
51MATK0.99472530
52PRPF4B0.99179164
53SIK10.97692916
54SGK20.97346467
55MAP3K100.97220560
56MAP3K60.96238976
57STK110.95461489
58IRAK30.94774813
59FGR0.93853151
60NTRK30.93829820
61PNCK0.93622866
62DYRK20.92775587
63MAP2K30.92665892
64BTK0.90856891
65ATR0.90564457
66AKT30.89278023
67CSK0.88343259
68CDK70.88046205
69GRK10.85838639
70MAP2K70.84603439
71CHUK0.84393471
72CDK30.81507274
73MAP3K70.81117598
74EPHB10.80937805
75MAPK130.78052273
76CAMK1G0.77843804
77NTRK20.77251562
78CSF1R0.76276441
79STK30.72812000
80PRKAA20.71854947
81STK160.71681547
82ACVR1B0.70438901
83EIF2AK20.69950529
84FLT30.69278482
85CAMKK10.69018665
86RET0.68770757
87MTOR0.67998368
88NLK0.65240444
89MINK10.65044579
90CHEK20.64873781
91STK40.63925585
92PLK20.63328901
93CAMK40.62431132
94EPHA30.62397218
95PRKD30.62324280
96ERBB20.60449932
97EEF2K0.60448449
98CAMK10.59191530
99IRAK20.58982825
100MARK20.58904070
101LRRK20.58663436
102PRKCH0.57829773
103PTK2B0.57582185
104DYRK1A0.56482428
105TGFBR10.56469917
106DMPK0.55885033
107CDK90.54664776
108ATM0.54583715
109CAMK1D0.54479255
110PDK10.53093725
111PRKAA10.52934623
112PDGFRB0.50997179
113CAMKK20.48837418
114MAP4K20.48134016
115GRK70.47746276
116CLK10.46458647
117ZAP700.46365055
118RPS6KA20.46352968
119TYK20.46318487
120CDK50.45486485
121DYRK30.45466547
122NEK60.44970013
123PAK40.44948347
124LYN0.44191260
125AKT10.44050669
126WNK30.43981505
127GRK60.43936055
128HCK0.43535069
129UHMK10.43052774
130TIE10.42929851
131SGK10.42043300
132RPS6KA60.41680289
133LCK0.41540746
134FYN0.41123237
135MAP3K110.40830556
136SYK0.40792349
137ADRBK10.40518242
138MAP4K10.40064218
139RPS6KC10.39724817
140RPS6KL10.39724817
141IRAK10.37750979
142ITK0.36868830
143TLK10.35960655
144IKBKE0.35723507
145SGK30.34697549
146MAPK140.34239686
147MAP3K140.31959034
148PRKG10.31331324
149EIF2AK30.29767394
150RPS6KB10.29577023
151PRKCZ0.29496363
152JAK30.28374677

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049502.62268751
2Non-homologous end-joining_Homo sapiens_hsa034502.53585594
3Long-term depression_Homo sapiens_hsa047301.54817579
4Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.52988105
5Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.52919964
6Transcriptional misregulation in cancer_Homo sapiens_hsa052021.43694585
7Fanconi anemia pathway_Homo sapiens_hsa034601.41745768
8Basal cell carcinoma_Homo sapiens_hsa052171.38465659
9Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.38256715
10Protein export_Homo sapiens_hsa030601.37743637
11* Notch signaling pathway_Homo sapiens_hsa043301.37427024
12Hematopoietic cell lineage_Homo sapiens_hsa046401.35654479
13Wnt signaling pathway_Homo sapiens_hsa043101.29432089
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.28419183
15Phospholipase D signaling pathway_Homo sapiens_hsa040721.27374134
16Circadian entrainment_Homo sapiens_hsa047131.23435525
17NF-kappa B signaling pathway_Homo sapiens_hsa040641.23296710
18Prolactin signaling pathway_Homo sapiens_hsa049171.22396698
19Fatty acid biosynthesis_Homo sapiens_hsa000611.18502740
20Toll-like receptor signaling pathway_Homo sapiens_hsa046201.18251502
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.17480646
22Renin secretion_Homo sapiens_hsa049241.15557801
23Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.13802526
24Choline metabolism in cancer_Homo sapiens_hsa052311.13514033
25Gap junction_Homo sapiens_hsa045401.13486545
26Acute myeloid leukemia_Homo sapiens_hsa052211.11251636
27Glutamatergic synapse_Homo sapiens_hsa047241.11148920
28Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10631225
29Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10629446
30Dopaminergic synapse_Homo sapiens_hsa047281.10465599
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.08674163
32Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.08414267
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.07912674
34Jak-STAT signaling pathway_Homo sapiens_hsa046301.07510320
35Type II diabetes mellitus_Homo sapiens_hsa049301.06178906
36GnRH signaling pathway_Homo sapiens_hsa049121.05846207
37Taste transduction_Homo sapiens_hsa047421.05559278
38Renal cell carcinoma_Homo sapiens_hsa052111.05480358
39Other glycan degradation_Homo sapiens_hsa005111.05248791
40alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.02544764
41Measles_Homo sapiens_hsa051621.01915176
42Morphine addiction_Homo sapiens_hsa050321.01691043
43Thyroid hormone signaling pathway_Homo sapiens_hsa049191.01541534
44Vascular smooth muscle contraction_Homo sapiens_hsa042701.01176137
45Homologous recombination_Homo sapiens_hsa034401.00956730
46Herpes simplex infection_Homo sapiens_hsa051681.00645537
47Insulin secretion_Homo sapiens_hsa049111.00563425
48Adherens junction_Homo sapiens_hsa045201.00547062
49Neurotrophin signaling pathway_Homo sapiens_hsa047220.99452411
50Chronic myeloid leukemia_Homo sapiens_hsa052200.98948733
51Osteoclast differentiation_Homo sapiens_hsa043800.97471087
52Axon guidance_Homo sapiens_hsa043600.96488037
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.95907819
54Oxytocin signaling pathway_Homo sapiens_hsa049210.94551685
55Cocaine addiction_Homo sapiens_hsa050300.93684197
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93511703
57Sphingolipid metabolism_Homo sapiens_hsa006000.93432382
58Basal transcription factors_Homo sapiens_hsa030220.93210113
59Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93200815
60Hedgehog signaling pathway_Homo sapiens_hsa043400.93176738
61Inositol phosphate metabolism_Homo sapiens_hsa005620.92089837
62MicroRNAs in cancer_Homo sapiens_hsa052060.92087445
63Estrogen signaling pathway_Homo sapiens_hsa049150.91728743
64Influenza A_Homo sapiens_hsa051640.89434195
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.87853194
66Leishmaniasis_Homo sapiens_hsa051400.87759850
67VEGF signaling pathway_Homo sapiens_hsa043700.87122908
68Endometrial cancer_Homo sapiens_hsa052130.86604371
69Nicotine addiction_Homo sapiens_hsa050330.86328976
70mTOR signaling pathway_Homo sapiens_hsa041500.86277970
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.86194509
72cAMP signaling pathway_Homo sapiens_hsa040240.84800343
73Lysine degradation_Homo sapiens_hsa003100.84695371
74Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.84525397
75Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84426816
76MAPK signaling pathway_Homo sapiens_hsa040100.82666202
77Colorectal cancer_Homo sapiens_hsa052100.80536354
78Spliceosome_Homo sapiens_hsa030400.79896706
79Longevity regulating pathway - mammal_Homo sapiens_hsa042110.79729021
80Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.79659600
81Small cell lung cancer_Homo sapiens_hsa052220.79383545
82Insulin resistance_Homo sapiens_hsa049310.78228701
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.78051136
84Tuberculosis_Homo sapiens_hsa051520.77938029
85N-Glycan biosynthesis_Homo sapiens_hsa005100.77883034
86Pancreatic cancer_Homo sapiens_hsa052120.77662743
87cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77088503
88Pathways in cancer_Homo sapiens_hsa052000.76416151
89HTLV-I infection_Homo sapiens_hsa051660.75493455
90FoxO signaling pathway_Homo sapiens_hsa040680.75356077
91Phototransduction_Homo sapiens_hsa047440.75340908
92Prostate cancer_Homo sapiens_hsa052150.75047893
93Non-small cell lung cancer_Homo sapiens_hsa052230.74475568
94Melanoma_Homo sapiens_hsa052180.74113755
95Primary immunodeficiency_Homo sapiens_hsa053400.73238258
96GABAergic synapse_Homo sapiens_hsa047270.73222817
97Mismatch repair_Homo sapiens_hsa034300.72133517
98Ribosome_Homo sapiens_hsa030100.71004597
99Linoleic acid metabolism_Homo sapiens_hsa005910.70844905
100Hepatitis B_Homo sapiens_hsa051610.70815660
101Salivary secretion_Homo sapiens_hsa049700.70571159
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.70457809
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.70114314
104Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.69729460
105PI3K-Akt signaling pathway_Homo sapiens_hsa041510.69676159
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.69621679
107Thyroid cancer_Homo sapiens_hsa052160.69088612
108ErbB signaling pathway_Homo sapiens_hsa040120.68296685
109Long-term potentiation_Homo sapiens_hsa047200.67934102
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67823432
111Type I diabetes mellitus_Homo sapiens_hsa049400.67781915
112ECM-receptor interaction_Homo sapiens_hsa045120.67714171
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67570405
114B cell receptor signaling pathway_Homo sapiens_hsa046620.67239685
115mRNA surveillance pathway_Homo sapiens_hsa030150.66473202
116Pancreatic secretion_Homo sapiens_hsa049720.66267111
117Serotonergic synapse_Homo sapiens_hsa047260.65843979
118Cell cycle_Homo sapiens_hsa041100.65039631
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64568644
120Renin-angiotensin system_Homo sapiens_hsa046140.64185193
121Dorso-ventral axis formation_Homo sapiens_hsa043200.63887310
122AMPK signaling pathway_Homo sapiens_hsa041520.63845378
123Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63821361
124Staphylococcus aureus infection_Homo sapiens_hsa051500.63091184
125TNF signaling pathway_Homo sapiens_hsa046680.63029820
126NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60923801
127RNA degradation_Homo sapiens_hsa030180.60857301
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.60749810
129Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60693500
130Toxoplasmosis_Homo sapiens_hsa051450.60514335
131Base excision repair_Homo sapiens_hsa034100.60168115
132Regulation of autophagy_Homo sapiens_hsa041400.59373246
133Protein digestion and absorption_Homo sapiens_hsa049740.59227150
134Melanogenesis_Homo sapiens_hsa049160.59203777
135Glioma_Homo sapiens_hsa052140.59111601
136Apoptosis_Homo sapiens_hsa042100.57838170
137Circadian rhythm_Homo sapiens_hsa047100.57769834
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57379628
139Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57318910
140Amoebiasis_Homo sapiens_hsa051460.57295477
141TGF-beta signaling pathway_Homo sapiens_hsa043500.57256057
142Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.56098081
143Platelet activation_Homo sapiens_hsa046110.55678400
144Insulin signaling pathway_Homo sapiens_hsa049100.55608890
145Calcium signaling pathway_Homo sapiens_hsa040200.55234274
146Arachidonic acid metabolism_Homo sapiens_hsa005900.55109807
147Alcoholism_Homo sapiens_hsa050340.54440383
148Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54393273
149Rap1 signaling pathway_Homo sapiens_hsa040150.54379767
150Chemokine signaling pathway_Homo sapiens_hsa040620.54374111
151Ras signaling pathway_Homo sapiens_hsa040140.53984756
152Hippo signaling pathway_Homo sapiens_hsa043900.53018223
153Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.52000388
154Ovarian steroidogenesis_Homo sapiens_hsa049130.51717380
155T cell receptor signaling pathway_Homo sapiens_hsa046600.51529548
156African trypanosomiasis_Homo sapiens_hsa051430.50463232
157Cholinergic synapse_Homo sapiens_hsa047250.50369311

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