LY9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.58031262
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.33494702
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.33494702
4antigen processing and presentation of endogenous antigen (GO:0019883)5.99594273
5regulation of B cell receptor signaling pathway (GO:0050855)5.57010813
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.52460737
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.24352463
8positive regulation by organism of defense response of other organism involved in symbiotic interact5.24352463
9modulation by symbiont of host immune response (GO:0052553)5.24352463
10positive regulation by symbiont of host defense response (GO:0052509)5.24352463
11modulation by symbiont of host defense response (GO:0052031)5.24352463
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.24352463
13negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.07686656
14negative regulation of cell killing (GO:0031342)5.07686656
15regulation of gamma-delta T cell differentiation (GO:0045586)4.96530501
16regulation of interferon-beta biosynthetic process (GO:0045357)4.89592025
17regulation of gamma-delta T cell activation (GO:0046643)4.72210935
18positive thymic T cell selection (GO:0045059)4.64103745
19negative thymic T cell selection (GO:0045060)4.62956808
20positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.62772714
21negative T cell selection (GO:0043383)4.62245586
22B cell receptor signaling pathway (GO:0050853)4.27376163
23positive regulation of interferon-alpha production (GO:0032727)4.17094297
24leukocyte aggregation (GO:0070486)4.14250603
25T cell migration (GO:0072678)4.08183570
26immunoglobulin mediated immune response (GO:0016064)4.05783292
27negative regulation of T cell mediated immunity (GO:0002710)4.01892749
28regulation of B cell differentiation (GO:0045577)4.01415694
29regulation of interferon-alpha production (GO:0032647)4.00407394
30regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.98419824
31positive regulation of B cell differentiation (GO:0045579)3.97857959
32negative regulation of lymphocyte mediated immunity (GO:0002707)3.96386446
33thymic T cell selection (GO:0045061)3.95101603
34response to interleukin-15 (GO:0070672)3.90687486
35regulation of T cell mediated cytotoxicity (GO:0001914)3.90617366
36regulation of interleukin-12 biosynthetic process (GO:0045075)3.85618374
37positive T cell selection (GO:0043368)3.83769056
38regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.82301775
39regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.78730049
40T cell selection (GO:0045058)3.75641566
41positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.70643596
42positive regulation of antigen processing and presentation (GO:0002579)3.70459070
43interferon-gamma production (GO:0032609)3.68405973
44cellular response to interleukin-15 (GO:0071350)3.67793549
45positive regulation of T cell mediated cytotoxicity (GO:0001916)3.66340064
46regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.64419206
47regulation of natural killer cell mediated immunity (GO:0002715)3.64419206
48tolerance induction (GO:0002507)3.61908901
49positive regulation of granulocyte differentiation (GO:0030854)3.59545198
50macrophage activation involved in immune response (GO:0002281)3.57744712
51response to type I interferon (GO:0034340)3.57254891
52neutrophil activation involved in immune response (GO:0002283)3.54591619
53type I interferon signaling pathway (GO:0060337)3.53855442
54cellular response to type I interferon (GO:0071357)3.53855442
55negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.52021651
56regulation of leukocyte mediated cytotoxicity (GO:0001910)3.51559781
57Arp2/3 complex-mediated actin nucleation (GO:0034314)3.48558558
58interferon-gamma-mediated signaling pathway (GO:0060333)3.44232114
59respiratory burst (GO:0045730)3.41544254
60regulation of cell killing (GO:0031341)3.40043123
61mast cell activation involved in immune response (GO:0002279)3.36860247
62mast cell degranulation (GO:0043303)3.36860247
63positive regulation of defense response to virus by host (GO:0002230)3.35866356
64response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.35611535
65response to host immune response (GO:0052572)3.35611535
66antigen receptor-mediated signaling pathway (GO:0050851)3.35145429
67regulation of alpha-beta T cell proliferation (GO:0046640)3.34634926
68NIK/NF-kappaB signaling (GO:0038061)3.31670248
69T cell costimulation (GO:0031295)3.30654012
70positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.29425774
71regulation of T cell tolerance induction (GO:0002664)3.29245238
72negative regulation of leukocyte mediated immunity (GO:0002704)3.27586271
73regulation of isotype switching to IgG isotypes (GO:0048302)3.25605818
74regulation of type I interferon-mediated signaling pathway (GO:0060338)3.25100892
75lymphocyte costimulation (GO:0031294)3.23918593
76regulation of T cell receptor signaling pathway (GO:0050856)3.23797157
77regulation of regulatory T cell differentiation (GO:0045589)3.23274025
78positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.21613020
79positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.21332683
80leukocyte cell-cell adhesion (GO:0007159)3.20272999
81positive regulation of cell killing (GO:0031343)3.19406652
82antigen processing and presentation via MHC class Ib (GO:0002475)3.19324744
83myeloid cell activation involved in immune response (GO:0002275)3.18927514
84B cell mediated immunity (GO:0019724)3.18389968
85mast cell activation (GO:0045576)3.17428363
86positive regulation of isotype switching (GO:0045830)3.16688989
87defense response to protozoan (GO:0042832)3.16470328
88activated T cell proliferation (GO:0050798)3.15950537
89positive regulation of T cell differentiation in thymus (GO:0033089)3.15761223
90response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.15515146
91response to host (GO:0075136)3.15515146
92response to host defenses (GO:0052200)3.15515146
93regulation of germinal center formation (GO:0002634)3.15411431
94regulation of antigen processing and presentation (GO:0002577)3.14349550
95negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.12998659
96JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.12959553
97T cell receptor signaling pathway (GO:0050852)3.11923177
98myeloid dendritic cell activation (GO:0001773)3.09773942
99positive regulation of interferon-beta production (GO:0032728)3.05631916
100regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04478194
101neutrophil activation (GO:0042119)3.03374010
102negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.03250171
103response to protozoan (GO:0001562)3.01966814
104B cell proliferation (GO:0042100)3.01168872
105lymph node development (GO:0048535)3.01014476
106regulation of response to interferon-gamma (GO:0060330)2.99136752
107regulation of T cell mediated immunity (GO:0002709)2.97936676
108cellular response to zinc ion (GO:0071294)2.96787708
109granulocyte activation (GO:0036230)2.95763200
110leukocyte degranulation (GO:0043299)2.95309739
111natural killer cell mediated immunity (GO:0002228)2.95278498
112natural killer cell mediated cytotoxicity (GO:0042267)2.95278498
113positive regulation of natural killer cell mediated immunity (GO:0002717)2.95187933
114negative regulation of phagocytosis (GO:0050765)2.94895867
115detection of bacterium (GO:0016045)2.94736636
116negative regulation of interleukin-12 production (GO:0032695)2.94041428
117myeloid dendritic cell differentiation (GO:0043011)2.92902411
118mucosal-associated lymphoid tissue development (GO:0048537)2.92527314
119Peyers patch development (GO:0048541)2.92527314
120negative regulation of adaptive immune response (GO:0002820)2.92451376
121mature B cell differentiation (GO:0002335)2.92433492
122germinal center formation (GO:0002467)2.89382787
123regulation of tolerance induction (GO:0002643)2.89226513
124positive regulation of interleukin-2 production (GO:0032743)2.88306034
125regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.88270959
126positive regulation of B cell mediated immunity (GO:0002714)2.87501500
127positive regulation of immunoglobulin mediated immune response (GO:0002891)2.87501500
128pinocytosis (GO:0006907)2.87445716
129B cell homeostasis (GO:0001782)2.86566870
130negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.86508942
131negative regulation of T-helper cell differentiation (GO:0045623)2.86508942
132positive regulation of T cell mediated immunity (GO:0002711)2.86080386
133positive regulation of alpha-beta T cell proliferation (GO:0046641)2.85362223
134positive regulation of humoral immune response (GO:0002922)2.84423508
135positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.84389409
136T cell proliferation (GO:0042098)2.82737755
137negative regulation of innate immune response (GO:0045824)2.82444211
138detection of other organism (GO:0098543)2.81805108
139dendritic cell chemotaxis (GO:0002407)2.80735107
140regulation of alpha-beta T cell activation (GO:0046634)2.80052079
141regulation of defense response to virus by host (GO:0050691)2.77747683
142dendritic cell migration (GO:0036336)2.77508684
143alpha-beta T cell differentiation (GO:0046632)2.76835327
144DNA deamination (GO:0045006)2.75998099

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.78029347
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.18317805
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.88147019
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.34305086
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.09130028
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.50336632
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.45120286
8* IRF8_27001747_Chip-Seq_BMDM_Mouse3.40590434
9* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.23176579
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.15616489
11BP1_19119308_ChIP-ChIP_Hs578T_Human3.13184820
12E2F7_22180533_ChIP-Seq_HELA_Human3.07009118
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.05076231
14* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.01229430
15* MYC_22102868_ChIP-Seq_BL_Human2.97375625
16* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.89073892
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.85526089
18RUNX_20019798_ChIP-Seq_JUKART_Human2.61703799
19* MYB_26560356_Chip-Seq_TH2_Human2.61496890
20VDR_21846776_ChIP-Seq_THP-1_Human2.60448723
21* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.59525376
22MYB_21317192_ChIP-Seq_ERMYB_Mouse2.59189433
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.53350212
24MAF_26560356_Chip-Seq_TH1_Human2.53118960
25SPI1_23547873_ChIP-Seq_NB4_Human2.29678277
26* MYB_26560356_Chip-Seq_TH1_Human2.29020405
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18754558
28RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.16228710
29* UTX_26944678_Chip-Seq_JUKART_Human2.15169777
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.14310747
31BRD4_27068464_Chip-Seq_AML-cells_Mouse2.11650324
32VDR_24763502_ChIP-Seq_THP-1_Human2.07333416
33* RUNX1_22412390_ChIP-Seq_EML_Mouse2.04259977
34NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.00210083
35SCL_19346495_ChIP-Seq_HPC-7_Human1.98376043
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.96903913
37* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.84457915
38SPI1_23127762_ChIP-Seq_K562_Human1.82940083
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.81515866
40TCF7_22412390_ChIP-Seq_EML_Mouse1.74808101
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.71177861
42* MAF_26560356_Chip-Seq_TH2_Human1.66854346
43* GATA3_27048872_Chip-Seq_THYMUS_Human1.66214975
44KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.60297032
45VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.59146096
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.57735705
47MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.56727424
48* PU_27001747_Chip-Seq_BMDM_Mouse1.54555211
49* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.48533754
50CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.45972866
51SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.44103565
52KDM2B_26808549_Chip-Seq_DND41_Human1.42208368
53ZNF274_21170338_ChIP-Seq_K562_Hela1.40399976
54KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.38988511
55GATA1_22025678_ChIP-Seq_K562_Human1.38542050
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.36746552
57* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.34739330
58CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32699032
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.31340448
60KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30155141
61FOXM1_23109430_ChIP-Seq_U2OS_Human1.27397421
62VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.27182267
63ELF1_17652178_ChIP-ChIP_JURKAT_Human1.26241161
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.24499683
65* GATA3_26560356_Chip-Seq_TH2_Human1.20794228
66SMRT_27268052_Chip-Seq_Bcells_Human1.19399912
67NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.17368854
68CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15208871
69GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13690584
70* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10458797
71CIITA_25753668_ChIP-Seq_RAJI_Human1.09656935
72STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.08981323
73GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.08736061
74TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.08439539
75CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06312984
76EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.06266934
77GATA3_26560356_Chip-Seq_TH1_Human1.06148845
78IRF1_19129219_ChIP-ChIP_H3396_Human1.05852166
79TFEB_21752829_ChIP-Seq_HELA_Human1.04971836
80EGR1_23403033_ChIP-Seq_LIVER_Mouse1.04542797
81PCGF2_27294783_Chip-Seq_ESCs_Mouse1.04125813
82* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03775568
83VDR_24787735_ChIP-Seq_THP-1_Human1.03670274
84PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02873264
85THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.02101189
86ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01723887
87TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.99390147
88VDR_22108803_ChIP-Seq_LS180_Human0.98623626
89PU.1_20513432_ChIP-Seq_Bcells_Mouse0.97688720
90RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.97355940
91EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96025976
92BCL6_27268052_Chip-Seq_Bcells_Human0.95452315
93HOXB4_20404135_ChIP-ChIP_EML_Mouse0.95415441
94* FOXP3_21729870_ChIP-Seq_TREG_Human0.95067943
95IKZF1_21737484_ChIP-ChIP_HCT116_Human0.93330333
96GATA1_19941827_ChIP-Seq_MEL_Mouse0.93273235
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91883590
98P300_27268052_Chip-Seq_Bcells_Human0.91318309
99PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.90269744
100STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90218074
101PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89896621
102NFE2_27457419_Chip-Seq_LIVER_Mouse0.89179247
103GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.88386607
104EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.87851107
105* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87203539
106BCAT_22108803_ChIP-Seq_LS180_Human0.86542313
107SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.86293545
108ER_23166858_ChIP-Seq_MCF-7_Human0.85827130
109PRDM14_20953172_ChIP-Seq_ESCs_Human0.85460215
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.85183396
111LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.83952050
112RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.83722842
113GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.81892566
114SUZ12_27294783_Chip-Seq_NPCs_Mouse0.81752833
115IGF1R_20145208_ChIP-Seq_DFB_Human0.81712423
116STAT1_20625510_ChIP-Seq_HELA_Human0.80716985
117NCOR1_26117541_ChIP-Seq_K562_Human0.79520919
118TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.79081355
119RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.78634894
120GATA3_21878914_ChIP-Seq_MCF-7_Human0.78360976
121LXR_22292898_ChIP-Seq_THP-1_Human0.77584941
122* TP53_22573176_ChIP-Seq_HFKS_Human0.77536132
123* VDR_23849224_ChIP-Seq_CD4+_Human0.74910532
124RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74340520
125FOXA1_27270436_Chip-Seq_PROSTATE_Human0.74217715
126FOXA1_25329375_ChIP-Seq_VCAP_Human0.74217715
127KDM2B_26808549_Chip-Seq_JURKAT_Human0.74209122
128* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.73400741
129GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72988664
130SPI1_20517297_ChIP-Seq_HL60_Human0.72838857
131FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71284378
132SMAD_19615063_ChIP-ChIP_OVARY_Human0.69281133
133GATA1_19941826_ChIP-Seq_K562_Human0.67797238
134GATA2_19941826_ChIP-Seq_K562_Human0.65873838
135BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.65617467

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.49777041
2MP0005671_abnormal_response_to3.49056307
3MP0005387_immune_system_phenotype3.42806390
4MP0001790_abnormal_immune_system3.42806390
5MP0001800_abnormal_humoral_immune3.38014696
6MP0003303_peritoneal_inflammation3.35659603
7MP0000685_abnormal_immune_system3.33618821
8MP0005000_abnormal_immune_tolerance3.19450789
9MP0002452_abnormal_antigen_presenting2.99830426
10MP0003763_abnormal_thymus_physiology2.99433255
11MP0003436_decreased_susceptibility_to2.97583165
12MP0006082_CNS_inflammation2.89242457
13MP0009785_altered_susceptibility_to2.86622811
14* MP0002723_abnormal_immune_serum2.85204040
15MP0002420_abnormal_adaptive_immunity2.77084630
16MP0001819_abnormal_immune_cell2.74753859
17MP0005025_abnormal_response_to2.69283621
18MP0002419_abnormal_innate_immunity2.65986769
19MP0005058_abnormal_lysosome_morphology2.59603993
20MP0002398_abnormal_bone_marrow2.43535093
21MP0002148_abnormal_hypersensitivity_rea2.36758589
22MP0002405_respiratory_system_inflammati2.29421828
23MP0000716_abnormal_immune_system2.28033389
24MP0003300_gastrointestinal_ulcer2.27905014
25MP0002166_altered_tumor_susceptibility2.18744197
26MP0004510_myositis2.12957318
27MP0000689_abnormal_spleen_morphology2.12951277
28MP0003172_abnormal_lysosome_physiology2.11346433
29MP0005464_abnormal_platelet_physiology2.10913618
30MP0009333_abnormal_splenocyte_physiolog2.04170050
31MP0004947_skin_inflammation2.03432344
32MP0002722_abnormal_immune_system1.99236649
33MP0001873_stomach_inflammation1.92235948
34MP0010155_abnormal_intestine_physiology1.89296874
35MP0002429_abnormal_blood_cell1.87599251
36MP0001845_abnormal_inflammatory_respons1.87192371
37MP0003724_increased_susceptibility_to1.85758567
38MP0002006_tumorigenesis1.81222949
39MP0002396_abnormal_hematopoietic_system1.76795906
40MP0000703_abnormal_thymus_morphology1.72031657
41MP0005310_abnormal_salivary_gland1.67457311
42MP0001853_heart_inflammation1.66536713
43MP0002933_joint_inflammation1.51993313
44MP0001533_abnormal_skeleton_physiology1.51574634
45MP0008877_abnormal_DNA_methylation1.47840051
46MP0003448_altered_tumor_morphology1.47698671
47MP0008469_abnormal_protein_level1.44613315
48MP0004381_abnormal_hair_follicle1.40752431
49MP0003866_abnormal_defecation1.40627732
50MP0000569_abnormal_digit_pigmentation1.36839520
51MP0003252_abnormal_bile_duct1.34198612
52MP0000465_gastrointestinal_hemorrhage1.33178270
53MP0000858_altered_metastatic_potential1.32494180
54MP0004808_abnormal_hematopoietic_stem1.30951711
55MP0010307_abnormal_tumor_latency1.27444348
56MP0009840_abnormal_foam_cell1.27320715
57MP0000604_amyloidosis1.25472601
58MP0009278_abnormal_bone_marrow1.24957058
59MP0005174_abnormal_tail_pigmentation1.24662224
60MP0001986_abnormal_taste_sensitivity1.23907004
61MP0003195_calcinosis1.22675448
62MP0003183_abnormal_peptide_metabolism1.17019344
63MP0003191_abnormal_cellular_cholesterol1.13458741
64MP0005397_hematopoietic_system_phenotyp1.12036769
65MP0001545_abnormal_hematopoietic_system1.12036769
66MP0001501_abnormal_sleep_pattern1.09676181
67MP0003787_abnormal_imprinting1.07719385
68MP0002998_abnormal_bone_remodeling1.05560901
69MP0000490_abnormal_crypts_of1.03658836
70MP0002009_preneoplasia0.98854141
71MP0001851_eye_inflammation0.98645353
72MP0010352_gastrointestinal_tract_polyps0.95721902
73MP0003878_abnormal_ear_physiology0.93339302
74MP0005377_hearing/vestibular/ear_phenot0.93339302
75MP0009764_decreased_sensitivity_to0.93280512
76MP0002928_abnormal_bile_duct0.91865158
77MP0002019_abnormal_tumor_incidence0.85273967
78MP0005076_abnormal_cell_differentiation0.85118585
79MP0002163_abnormal_gland_morphology0.83816526
80MP0000343_altered_response_to0.83693759
81MP0000015_abnormal_ear_pigmentation0.82454921
82MP0002876_abnormal_thyroid_physiology0.80755371
83MP0002693_abnormal_pancreas_physiology0.79516561
84MP0009763_increased_sensitivity_to0.78856866
85MP0008872_abnormal_physiological_respon0.78530002
86MP0005645_abnormal_hypothalamus_physiol0.77708612
87MP0005166_decreased_susceptibility_to0.77593897
88MP0002102_abnormal_ear_morphology0.75455252
89MP0003646_muscle_fatigue0.75315407
90MP0008961_abnormal_basal_metabolism0.73584300
91MP0003566_abnormal_cell_adhesion0.72335341
92MP0005084_abnormal_gallbladder_morpholo0.70595130
93MP0002254_reproductive_system_inflammat0.67782074
94MP0003075_altered_response_to0.67682782
95MP0002136_abnormal_kidney_physiology0.67107714
96MP0003091_abnormal_cell_migration0.65809901
97MP0003786_premature_aging0.65543857
98MP0001765_abnormal_ion_homeostasis0.65533025
99MP0000372_irregular_coat_pigmentation0.65136154
100MP0001919_abnormal_reproductive_system0.64741756
101MP0003690_abnormal_glial_cell0.64357429
102MP0008057_abnormal_DNA_replication0.63657548
103MP0005023_abnormal_wound_healing0.63462822
104MP0004130_abnormal_muscle_cell0.61934143
105MP0003795_abnormal_bone_structure0.61650234
106MP0005551_abnormal_eye_electrophysiolog0.61523635
107MP0005257_abnormal_intraocular_pressure0.61307519
108MP0000609_abnormal_liver_physiology0.61271739
109MP0001663_abnormal_digestive_system0.61093387
110MP0000371_diluted_coat_color0.59718980
111MP0000249_abnormal_blood_vessel0.59380658
112MP0005379_endocrine/exocrine_gland_phen0.58282875
113MP0003828_pulmonary_edema0.57374364
114MP0005075_abnormal_melanosome_morpholog0.57253482
115MP0005390_skeleton_phenotype0.57185334
116MP0004043_abnormal_pH_regulation0.56452680
117MP0002277_abnormal_respiratory_mucosa0.56324526
118MP0003045_fibrosis0.55552236
119MP0003656_abnormal_erythrocyte_physiolo0.55181014
120MP0004142_abnormal_muscle_tone0.54567816
121MP0005083_abnormal_biliary_tract0.53372851
122MP0002138_abnormal_hepatobiliary_system0.52777321
123MP0003453_abnormal_keratinocyte_physiol0.52458511
124MP0008995_early_reproductive_senescence0.49986109
125MP0002095_abnormal_skin_pigmentation0.49306659
126MP0001348_abnormal_lacrimal_gland0.49063730
127MP0000598_abnormal_liver_morphology0.47845947
128MP0003077_abnormal_cell_cycle0.45801167
129MP0000313_abnormal_cell_death0.45450233
130MP0008873_increased_physiological_sensi0.44208258
131MP0005621_abnormal_cell_physiology0.42720724
132MP0002132_abnormal_respiratory_system0.42068514
133MP0009765_abnormal_xenobiotic_induced0.39695422

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.50562215
2Eczematoid dermatitis (HP:0000976)5.14742402
3Recurrent bacterial skin infections (HP:0005406)4.70168227
4Chronic otitis media (HP:0000389)4.56458590
5Elevated erythrocyte sedimentation rate (HP:0003565)4.49915826
6Recurrent viral infections (HP:0004429)4.40205506
7Recurrent bronchitis (HP:0002837)4.22900091
8Recurrent fungal infections (HP:0002841)4.21089041
9T lymphocytopenia (HP:0005403)4.14379480
10Myositis (HP:0100614)4.12966464
11Abnormality of T cell number (HP:0011839)4.04891524
12Increased cerebral lipofuscin (HP:0011813)4.04187104
13IgM deficiency (HP:0002850)3.88079927
14Abnormality of macrophages (HP:0004311)3.85693803
15Stomatitis (HP:0010280)3.82755348
16Mediastinal lymphadenopathy (HP:0100721)3.76658594
17Nasal polyposis (HP:0100582)3.76472735
18Recurrent gram-negative bacterial infections (HP:0005420)3.66067212
19Autoimmune thrombocytopenia (HP:0001973)3.63893377
20Agammaglobulinemia (HP:0004432)3.55112787
21Recurrent skin infections (HP:0001581)3.53503496
22Vacuolated lymphocytes (HP:0001922)3.53348281
23Obstructive lung disease (HP:0006536)3.53037094
24Chronic obstructive pulmonary disease (HP:0006510)3.53037094
25Vasculitis (HP:0002633)3.49604390
26Meningitis (HP:0001287)3.48530917
27Inflammation of the large intestine (HP:0002037)3.45381323
28Chronic mucocutaneous candidiasis (HP:0002728)3.44285128
29Recurrent cutaneous fungal infections (HP:0011370)3.44285128
30Abnormality of T cells (HP:0002843)3.43449768
31Abnormal delayed hypersensitivity skin test (HP:0002963)3.39183862
32Panhypogammaglobulinemia (HP:0003139)3.37706598
33Pustule (HP:0200039)3.36576916
34Cellulitis (HP:0100658)3.34714677
35Gastrointestinal inflammation (HP:0004386)3.33010806
36Increased neuronal autofluorescent lipopigment (HP:0002074)3.28812493
37Stomach cancer (HP:0012126)3.23571203
38Abnormality of the nasal mucosa (HP:0000433)3.23505028
39Colitis (HP:0002583)3.23237497
40Orchitis (HP:0100796)3.21435210
41Retrobulbar optic neuritis (HP:0100654)3.21043668
42Optic neuritis (HP:0100653)3.21043668
43Gastrointestinal infarctions (HP:0005244)3.10334144
44Lymphopenia (HP:0001888)3.08320981
45Abnormality of the prostate (HP:0008775)3.06196681
46Abnormality of cells of the lymphoid lineage (HP:0012140)3.00258535
47Gastrointestinal stroma tumor (HP:0100723)2.98461230
48Spontaneous hematomas (HP:0007420)2.87054108
49Keratoconjunctivitis (HP:0001096)2.85555355
50Dysostosis multiplex (HP:0000943)2.85101972
51Gingivitis (HP:0000230)2.78630031
52Pulmonary infiltrates (HP:0002113)2.77820870
53Leukocytosis (HP:0001974)2.77367107
54Abnormality of T cell physiology (HP:0011840)2.74502051
55IgG deficiency (HP:0004315)2.73108033
56Loss of speech (HP:0002371)2.72113390
57Severe combined immunodeficiency (HP:0004430)2.71340380
58Combined immunodeficiency (HP:0005387)2.70293503
59Abnormality of liposaccharide metabolism (HP:0010968)2.70042729
60Abnormality of glycosphingolipid metabolism (HP:0004343)2.70042729
61Abnormality of glycolipid metabolism (HP:0010969)2.70042729
62Chronic sinusitis (HP:0011109)2.68153999
63Thyroiditis (HP:0100646)2.67728140
64Eosinophilia (HP:0001880)2.67600434
65Recurrent sinusitis (HP:0011108)2.63828312
66Emphysema (HP:0002097)2.63695537
67Increased IgE level (HP:0003212)2.61270171
68Congenital stationary night blindness (HP:0007642)2.59254566
69Osteomyelitis (HP:0002754)2.53689661
70Encephalitis (HP:0002383)2.50634977
71Interstitial pulmonary disease (HP:0006530)2.49427545
72Chronic diarrhea (HP:0002028)2.49408455
73Disinhibition (HP:0000734)2.49354331
74Papilloma (HP:0012740)2.49339637
75Verrucae (HP:0200043)2.49339637
76Periodontitis (HP:0000704)2.49320317
77Abnormality of eosinophils (HP:0001879)2.48942983
78Thrombocytosis (HP:0001894)2.47990955
79Arterial thrombosis (HP:0004420)2.45256482
80Prostate neoplasm (HP:0100787)2.43385533
81Abnormality of the fingertips (HP:0001211)2.43099729
82Hypochromic anemia (HP:0001931)2.37251499
83Abnormality of the pleura (HP:0002103)2.37174292
84IgA deficiency (HP:0002720)2.36794647
85Granulocytopenia (HP:0001913)2.35816258
86Mucopolysacchariduria (HP:0008155)2.33482384
87Urinary glycosaminoglycan excretion (HP:0003541)2.33482384
88Systemic lupus erythematosus (HP:0002725)2.32154311
89Hemoptysis (HP:0002105)2.30963733
90Hypoproteinemia (HP:0003075)2.28437656
91Hematochezia (HP:0002573)2.27806719
92Chest pain (HP:0100749)2.26813415
93Hypergammaglobulinemia (HP:0010702)2.26390411
94Bronchitis (HP:0012387)2.26358899
95Pulmonary embolism (HP:0002204)2.23264050
96Recurrent pneumonia (HP:0006532)2.22922318
97B lymphocytopenia (HP:0010976)2.22879725
98Abnormality of B cell number (HP:0010975)2.22879725
99Myocardial infarction (HP:0001658)2.22457877
100Hypoplasia of the thymus (HP:0000778)2.20900104
101Abnormality of mucopolysaccharide metabolism (HP:0011020)2.20851818
102Abnormality of polysaccharide metabolism (HP:0011012)2.20851818
103Abnormality of glycosaminoglycan metabolism (HP:0004371)2.20851818
104Autoimmune hemolytic anemia (HP:0001890)2.18147694
105Restrictive lung disease (HP:0002091)2.17676750
106Lymphoma (HP:0002665)2.17109892
107Gingival bleeding (HP:0000225)2.16291941
108Anorexia (HP:0002039)2.16265337
109Increased IgM level (HP:0003496)2.15399886
110Gangrene (HP:0100758)2.13085826
111Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.12299188
112Urticaria (HP:0001025)2.12181349
113Keratoconjunctivitis sicca (HP:0001097)2.11736231
114Sepsis (HP:0100806)2.11483026
115Hypochromic microcytic anemia (HP:0004840)2.11288879
116Joint swelling (HP:0001386)2.05941053
117Alveolar cell carcinoma (HP:0006519)2.05748903
118Absent rod-and cone-mediated responses on ERG (HP:0007688)2.00407049
119Prolonged bleeding time (HP:0003010)1.99477507
120Abnormality of the renal cortex (HP:0011035)1.96142540
121Attenuation of retinal blood vessels (HP:0007843)1.92472270
122Neutropenia (HP:0001875)1.91703738
123Skin rash (HP:0000988)1.91505615
124Pulmonary fibrosis (HP:0002206)1.91449219
125Neoplasm of the tracheobronchial system (HP:0100552)1.90517095
126Abnormality of male internal genitalia (HP:0000022)1.85909093
127Keratitis (HP:0000491)1.83183528

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.61921464
2TXK3.50814272
3TYK23.14099131
4BLK2.75442964
5JAK32.68009581
6MAP3K142.61818680
7ZAP702.50423341
8TBK12.49336676
9KIT2.46218766
10IKBKE2.34681178
11JAK12.27994492
12STK102.24879191
13ITK2.22434640
14GRK62.10790805
15FRK2.05484373
16BMPR22.05211569
17SYK2.04007486
18IRAK42.00560932
19RIPK42.00293858
20CSF1R1.96797006
21ERN11.84341502
22FGFR41.83878104
23BTK1.83710189
24MAP3K131.79743298
25LCK1.74612197
26CSK1.74515976
27MAP3K101.72624119
28IKBKB1.64389629
29FES1.62534077
30HCK1.62409621
31IRAK31.61807862
32TEC1.52275231
33ADRBK21.50435801
34LRRK21.45083215
35TLK11.42749443
36FGFR31.36949717
37CAMKK21.36125727
38SIK21.28640680
39LYN1.28488170
40GRK11.22806026
41PKN21.22468951
42EEF2K1.21526385
43MARK31.15831669
44TRIB31.15478782
45ZAK1.14722912
46CDK191.14315334
47EPHB11.12273333
48TGFBR21.12187129
49PASK1.11643518
50TESK21.09459746
51CDK121.04633164
52MAP2K21.03665225
53RPS6KA41.02227973
54NME21.01641780
55CHUK1.01133805
56TAOK31.00252222
57PIM11.00015891
58JAK20.98351273
59PIK3CG0.96550102
60PRKCQ0.95900358
61CAMKK10.95874386
62CLK10.95721929
63MAP2K30.95516532
64NLK0.86569665
65KDR0.84967070
66PRKCH0.84597805
67MST40.80317909
68NUAK10.77338185
69MAP4K20.76856692
70TTN0.73067900
71TNK20.71613965
72FGR0.67692605
73ALK0.66891817
74PTK60.61714215
75SIK30.60273363
76SCYL20.59834898
77PRPF4B0.59362369
78MAPK70.57496619
79EPHA30.57050761
80CDK40.57049794
81NEK90.55879390
82PINK10.55723619
83STK40.53938684
84EGFR0.53542750
85ACVR1B0.52344715
86PTK2B0.52049277
87FLT30.50331402
88ABL10.50228661
89FYN0.49566823
90PDK10.48729247
91PRKD20.48545889
92WNK40.47697010
93OXSR10.46581826
94STK110.46121488
95GRK70.45522789
96CAMK1D0.45093637
97PIM20.45028552
98BCKDK0.44953755
99MAPK120.44815232
100MAP2K60.43342016
101NEK20.41900663
102MAP3K80.41593345
103MAPK130.41410398
104MAPKAPK30.40682730
105PRKCD0.38135611
106HIPK20.36646907
107CDK60.34547789
108BRD40.34200438
109ADRBK10.33972990
110CDK90.32964229
111PDGFRB0.32131337
112INSR0.32130804
113MATK0.32066381
114CAMK1G0.32020605
115BMPR1B0.31008544
116MARK20.30697104
117RPS6KA50.29679770
118MAPK110.28317509
119EIF2AK30.28171140
120MAP3K110.27851827
121INSRR0.27389612
122IGF1R0.27158314
123MAPKAPK20.27114238
124MAPK40.26520279
125TRPM70.25377274
126SIK10.25189759
127STK380.25171853
128MAP3K70.25038297
129RPS6KA60.23350338
130MAP3K30.22972628
131RIPK10.22776787
132TAOK10.20980930
133STK240.20065454
134MAPK30.19894448
135IRAK10.18546345
136SRC0.18405155

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.91167981
2Leishmaniasis_Homo sapiens_hsa051402.93250808
3B cell receptor signaling pathway_Homo sapiens_hsa046622.93125368
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.74873663
5Antigen processing and presentation_Homo sapiens_hsa046122.63422036
6Osteoclast differentiation_Homo sapiens_hsa043802.57799191
7Measles_Homo sapiens_hsa051622.51840666
8Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.51348579
9T cell receptor signaling pathway_Homo sapiens_hsa046602.40776085
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.40315140
11Intestinal immune network for IgA production_Homo sapiens_hsa046722.21611011
12Staphylococcus aureus infection_Homo sapiens_hsa051502.13150125
13Toll-like receptor signaling pathway_Homo sapiens_hsa046202.11811321
14Graft-versus-host disease_Homo sapiens_hsa053322.09885376
15Hematopoietic cell lineage_Homo sapiens_hsa046401.93805148
16Allograft rejection_Homo sapiens_hsa053301.91512258
17Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.90734830
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.85248175
19Glycosaminoglycan degradation_Homo sapiens_hsa005311.81405743
20Tuberculosis_Homo sapiens_hsa051521.73918449
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.72850908
22Lysosome_Homo sapiens_hsa041421.67929609
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.65613562
24Herpes simplex infection_Homo sapiens_hsa051681.64492008
25Influenza A_Homo sapiens_hsa051641.58062741
26Toxoplasmosis_Homo sapiens_hsa051451.57039177
27Pertussis_Homo sapiens_hsa051331.56030398
28Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.54541438
29Jak-STAT signaling pathway_Homo sapiens_hsa046301.53345039
30Legionellosis_Homo sapiens_hsa051341.51343624
31Malaria_Homo sapiens_hsa051441.48963481
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.46123838
33Shigellosis_Homo sapiens_hsa051311.46030425
34Chemokine signaling pathway_Homo sapiens_hsa040621.43483236
35Apoptosis_Homo sapiens_hsa042101.41354359
36Viral myocarditis_Homo sapiens_hsa054161.39698251
37Hepatitis B_Homo sapiens_hsa051611.32399886
38TNF signaling pathway_Homo sapiens_hsa046681.32353238
39Other glycan degradation_Homo sapiens_hsa005111.28730905
40Leukocyte transendothelial migration_Homo sapiens_hsa046701.27394857
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.25817327
42Acute myeloid leukemia_Homo sapiens_hsa052211.18091390
43Salmonella infection_Homo sapiens_hsa051321.16482151
44Chronic myeloid leukemia_Homo sapiens_hsa052201.03454922
45Hepatitis C_Homo sapiens_hsa051601.03015428
46Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.02174615
47Pancreatic cancer_Homo sapiens_hsa052121.01361942
48Asthma_Homo sapiens_hsa053101.00486937
49Rheumatoid arthritis_Homo sapiens_hsa053231.00083858
50Autoimmune thyroid disease_Homo sapiens_hsa053200.99328594
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.99311232
52Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.96751749
53Epstein-Barr virus infection_Homo sapiens_hsa051690.96479470
54Phototransduction_Homo sapiens_hsa047440.95236119
55Platelet activation_Homo sapiens_hsa046110.88547788
56SNARE interactions in vesicular transport_Homo sapiens_hsa041300.88100443
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.84490385
58Phagosome_Homo sapiens_hsa041450.83985790
59Type I diabetes mellitus_Homo sapiens_hsa049400.82965490
60AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82667538
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.82578130
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.81426705
63Viral carcinogenesis_Homo sapiens_hsa052030.78368976
64Linoleic acid metabolism_Homo sapiens_hsa005910.77263653
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.76560302
66HTLV-I infection_Homo sapiens_hsa051660.75626944
67Regulation of autophagy_Homo sapiens_hsa041400.74033454
68VEGF signaling pathway_Homo sapiens_hsa043700.73436248
69African trypanosomiasis_Homo sapiens_hsa051430.67319637
70Prolactin signaling pathway_Homo sapiens_hsa049170.67305186
71Caffeine metabolism_Homo sapiens_hsa002320.67086441
72ABC transporters_Homo sapiens_hsa020100.66207588
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64254267
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62038976
75Non-small cell lung cancer_Homo sapiens_hsa052230.59271434
76Endocytosis_Homo sapiens_hsa041440.59157523
77Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58906874
78Colorectal cancer_Homo sapiens_hsa052100.57716752
79Small cell lung cancer_Homo sapiens_hsa052220.54564061
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.53811597
81Nitrogen metabolism_Homo sapiens_hsa009100.50819650
82Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49822537
83Notch signaling pathway_Homo sapiens_hsa043300.48624828
84HIF-1 signaling pathway_Homo sapiens_hsa040660.47122180
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46815216
86Base excision repair_Homo sapiens_hsa034100.45972946
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.44961791
88Arachidonic acid metabolism_Homo sapiens_hsa005900.44565758
89Olfactory transduction_Homo sapiens_hsa047400.43621677
90Ether lipid metabolism_Homo sapiens_hsa005650.43286144
91Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.43217236
92mTOR signaling pathway_Homo sapiens_hsa041500.41034762
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39229771
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.39223187
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36456872
96Systemic lupus erythematosus_Homo sapiens_hsa053220.36377614
97Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35598047
98Amoebiasis_Homo sapiens_hsa051460.35435872
99Insulin resistance_Homo sapiens_hsa049310.34233469
100p53 signaling pathway_Homo sapiens_hsa041150.34110700
101Morphine addiction_Homo sapiens_hsa050320.33957278
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.33609545
103Carbohydrate digestion and absorption_Homo sapiens_hsa049730.32835235
104Renal cell carcinoma_Homo sapiens_hsa052110.32564570
105Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.32325483
106DNA replication_Homo sapiens_hsa030300.29816902
107Glycerolipid metabolism_Homo sapiens_hsa005610.29595606
108Collecting duct acid secretion_Homo sapiens_hsa049660.29252858
109FoxO signaling pathway_Homo sapiens_hsa040680.28722786
110Inositol phosphate metabolism_Homo sapiens_hsa005620.28467781
111Dorso-ventral axis formation_Homo sapiens_hsa043200.28268941
112RNA degradation_Homo sapiens_hsa030180.27547573
113Proteoglycans in cancer_Homo sapiens_hsa052050.26950866
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.24496593
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24429670
116MAPK signaling pathway_Homo sapiens_hsa040100.24256295
117Ribosome_Homo sapiens_hsa030100.24145677
118Non-homologous end-joining_Homo sapiens_hsa034500.23866700
119MicroRNAs in cancer_Homo sapiens_hsa052060.23506070
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23334772
121Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.23327153
122Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.22408206
123Circadian rhythm_Homo sapiens_hsa047100.21396855
124Type II diabetes mellitus_Homo sapiens_hsa049300.20796819
125Prostate cancer_Homo sapiens_hsa052150.18776002
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.17467342
127Choline metabolism in cancer_Homo sapiens_hsa052310.13879824
128Ovarian steroidogenesis_Homo sapiens_hsa049130.13298569
129Ras signaling pathway_Homo sapiens_hsa040140.13221552
130Taste transduction_Homo sapiens_hsa047420.06035244

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