LRRN3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.89652253
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.77207901
3vocalization behavior (GO:0071625)5.63762849
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.42316162
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.14795544
6synaptic vesicle exocytosis (GO:0016079)5.04533266
7locomotory exploration behavior (GO:0035641)4.98793163
8synaptic vesicle maturation (GO:0016188)4.92857520
9regulation of glutamate receptor signaling pathway (GO:1900449)4.87170267
10protein localization to synapse (GO:0035418)4.86655455
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.81183593
12glutamate secretion (GO:0014047)4.77775445
13regulation of synaptic vesicle exocytosis (GO:2000300)4.62529244
14synaptic vesicle docking involved in exocytosis (GO:0016081)4.59843675
15ionotropic glutamate receptor signaling pathway (GO:0035235)4.57115413
16layer formation in cerebral cortex (GO:0021819)4.56009216
17neuron recognition (GO:0008038)4.55316303
18neurotransmitter-gated ion channel clustering (GO:0072578)4.46418282
19exploration behavior (GO:0035640)4.40000459
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.28176498
21retinal ganglion cell axon guidance (GO:0031290)4.26801493
22neurofilament cytoskeleton organization (GO:0060052)4.24495884
23neurotransmitter secretion (GO:0007269)4.19921011
24axonal fasciculation (GO:0007413)4.18575562
25glutamate receptor signaling pathway (GO:0007215)4.17517172
26postsynaptic membrane organization (GO:0001941)4.17028602
27dendritic spine morphogenesis (GO:0060997)4.14916355
28regulation of synaptic vesicle transport (GO:1902803)4.10074237
29presynaptic membrane assembly (GO:0097105)4.09536347
30synaptic transmission, glutamatergic (GO:0035249)4.08919850
31regulation of synapse structural plasticity (GO:0051823)4.08450318
32behavioral response to nicotine (GO:0035095)4.04884792
33regulation of long-term neuronal synaptic plasticity (GO:0048169)4.04815511
34proline transport (GO:0015824)4.01772687
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.00554567
36pyrimidine nucleobase catabolic process (GO:0006208)3.99214518
37regulation of neuronal synaptic plasticity (GO:0048168)3.97611224
38neuron-neuron synaptic transmission (GO:0007270)3.96679889
39positive regulation of synapse maturation (GO:0090129)3.90644154
40establishment of mitochondrion localization (GO:0051654)3.84911231
41positive regulation of amino acid transport (GO:0051957)3.80810441
42presynaptic membrane organization (GO:0097090)3.80236085
43forebrain neuron differentiation (GO:0021879)3.80166672
44nonmotile primary cilium assembly (GO:0035058)3.68872989
45regulation of excitatory postsynaptic membrane potential (GO:0060079)3.68218023
46neuronal action potential propagation (GO:0019227)3.64351412
47sequestering of actin monomers (GO:0042989)3.62066469
48regulation of postsynaptic membrane potential (GO:0060078)3.59317588
49dendrite morphogenesis (GO:0048813)3.57294712
50innervation (GO:0060384)3.56190646
51auditory behavior (GO:0031223)3.54484593
52gamma-aminobutyric acid signaling pathway (GO:0007214)3.53099020
53gamma-aminobutyric acid transport (GO:0015812)3.52914830
54negative regulation of oligodendrocyte differentiation (GO:0048715)3.52049930
55regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.51466132
56membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.50975762
57cell migration in hindbrain (GO:0021535)3.50897488
58negative regulation of synaptic transmission, GABAergic (GO:0032229)3.49398176
59negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.48255972
60positive regulation of membrane potential (GO:0045838)3.47318936
61regulation of dendritic spine morphogenesis (GO:0061001)3.46492460
62long-term memory (GO:0007616)3.44914647
63neurotransmitter transport (GO:0006836)3.41105354
64regulation of synaptic transmission, glutamatergic (GO:0051966)3.38309003
65long-term synaptic potentiation (GO:0060291)3.37085690
66nucleobase catabolic process (GO:0046113)3.33329695
67short-term memory (GO:0007614)3.32671780
68response to histamine (GO:0034776)3.30840471
69positive regulation of synapse assembly (GO:0051965)3.28227800
70negative regulation of axon guidance (GO:1902668)3.28190221
71behavioral fear response (GO:0001662)3.28044982
72behavioral defense response (GO:0002209)3.28044982
73synapse assembly (GO:0007416)3.27915302
74positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.26943226
75regulation of synaptic plasticity (GO:0048167)3.26922848
76negative regulation of microtubule polymerization (GO:0031115)3.26241769
77transmission of nerve impulse (GO:0019226)3.25978476
78cerebellar granule cell differentiation (GO:0021707)3.25722105
79synaptic vesicle endocytosis (GO:0048488)3.24979804
80positive regulation of synaptic transmission, GABAergic (GO:0032230)3.24311028
81neuronal action potential (GO:0019228)3.21104755
82positive regulation of neurotransmitter secretion (GO:0001956)3.20522815
83positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.19470189
84mechanosensory behavior (GO:0007638)3.19214607
85regulation of neurotransmitter levels (GO:0001505)3.19193423
86regulation of neurotransmitter secretion (GO:0046928)3.17713012
87activation of protein kinase A activity (GO:0034199)3.17330176
88startle response (GO:0001964)3.16072274
89G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.15642196
90regulation of synaptic transmission, GABAergic (GO:0032228)3.14730745
91response to auditory stimulus (GO:0010996)3.14531244
92central nervous system projection neuron axonogenesis (GO:0021952)3.14295155
93G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.13684549
94regulation of synapse maturation (GO:0090128)3.12933026
95regulation of respiratory system process (GO:0044065)3.12405068
96positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.11640341
97fear response (GO:0042596)3.11021627
98membrane hyperpolarization (GO:0060081)3.10275294
99prepulse inhibition (GO:0060134)3.09823297
100neuron fate determination (GO:0048664)3.09370992
101learning (GO:0007612)3.09176034
102membrane depolarization (GO:0051899)3.07605804
103regulation of vesicle fusion (GO:0031338)3.06244282
104positive regulation of potassium ion transmembrane transport (GO:1901381)3.05864006
105protein localization to cilium (GO:0061512)3.05333635
106neuronal stem cell maintenance (GO:0097150)3.05232381
107negative regulation of cytosolic calcium ion concentration (GO:0051481)3.04073150
108heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)3.03800023
109positive regulation of dendritic spine morphogenesis (GO:0061003)3.02819009
110regulation of dendritic spine development (GO:0060998)3.02177910
111neuromuscular synaptic transmission (GO:0007274)3.01894355
112cerebellar Purkinje cell differentiation (GO:0021702)3.01517600
113dendrite development (GO:0016358)3.01045004
114cellular potassium ion homeostasis (GO:0030007)3.00336382
115synapse organization (GO:0050808)2.99216335
116positive regulation of dendritic spine development (GO:0060999)2.98858833
117positive regulation of neurotransmitter transport (GO:0051590)2.97310820
118positive regulation of mitochondrial fission (GO:0090141)2.95878878
119establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.94757465
120mitochondrion transport along microtubule (GO:0047497)2.94757465
121behavioral response to cocaine (GO:0048148)2.94426227
122mating behavior (GO:0007617)2.94360954
123regulation of development, heterochronic (GO:0040034)2.93071853
124calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.92959598
125regulation of neurotransmitter transport (GO:0051588)2.91571578
126intraspecies interaction between organisms (GO:0051703)2.91235948
127limb bud formation (GO:0060174)2.91119859
128synaptic transmission, cholinergic (GO:0007271)2.91088511
129regulation of feeding behavior (GO:0060259)2.81419917
130cochlea development (GO:0090102)2.80888040
131negative regulation of axon extension (GO:0030517)2.78899910
132axon ensheathment in central nervous system (GO:0032291)2.77493765
133central nervous system myelination (GO:0022010)2.77493765
134adult walking behavior (GO:0007628)2.77483005
135epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.75727680
136regulation of glutamate secretion (GO:0014048)2.75193270
137neuronal ion channel clustering (GO:0045161)2.74592230
138regulation of timing of cell differentiation (GO:0048505)2.73807100
139regulation of amino acid transport (GO:0051955)2.71120233
140behavioral response to ethanol (GO:0048149)2.71060956
141adult behavior (GO:0030534)2.70691755
142membrane depolarization during action potential (GO:0086010)2.69134491
143activated T cell proliferation (GO:0050798)2.68888844
144regulation of synapse assembly (GO:0051963)2.66086956
145axon extension involved in axon guidance (GO:0048846)2.63968404
146neuron projection extension involved in neuron projection guidance (GO:1902284)2.63968404
147negative regulation of amino acid transport (GO:0051956)2.63453349
148regulation of axon guidance (GO:1902667)2.63144320
149negative regulation of glial cell differentiation (GO:0045686)2.62697058
150regulation of respiratory gaseous exchange (GO:0043576)2.62012258
151regulation of action potential (GO:0098900)2.60596935

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.19657091
2GBX2_23144817_ChIP-Seq_PC3_Human4.08989626
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.12140729
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.07749809
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.97674092
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.70035577
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.65949703
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.65949703
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.62224399
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.61946311
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.61097282
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.56448101
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.52034264
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.49887217
15NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44449555
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38664404
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.36738045
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.36563908
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.25976197
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.24134075
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.19137531
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.16571328
23TAF15_26573619_Chip-Seq_HEK293_Human2.15969643
24* REST_18959480_ChIP-ChIP_MESCs_Mouse2.15803597
25CTBP2_25329375_ChIP-Seq_LNCAP_Human2.11231088
26DROSHA_22980978_ChIP-Seq_HELA_Human2.08924875
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.02305819
28AR_21572438_ChIP-Seq_LNCaP_Human1.91550268
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.89987673
30IKZF1_21737484_ChIP-ChIP_HCT116_Human1.88272293
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.87577592
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.83543522
33ZFP57_27257070_Chip-Seq_ESCs_Mouse1.78662643
34PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.68577487
35* SMAD4_21799915_ChIP-Seq_A2780_Human1.65070450
36* CBX2_27304074_Chip-Seq_ESCs_Mouse1.62019715
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60311939
38* P300_19829295_ChIP-Seq_ESCs_Human1.59535928
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58566832
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.56293919
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56093194
42IGF1R_20145208_ChIP-Seq_DFB_Human1.55026611
43MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.54333853
44* ZNF274_21170338_ChIP-Seq_K562_Hela1.51912160
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.49967220
46* EWS_26573619_Chip-Seq_HEK293_Human1.47977948
47EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44167650
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.41617800
49* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41095528
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.41013637
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.40708798
52* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40393849
53* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38961434
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.38585450
55POU5F1_16153702_ChIP-ChIP_HESCs_Human1.36833556
56* RNF2_27304074_Chip-Seq_NSC_Mouse1.36618266
57* AR_25329375_ChIP-Seq_VCAP_Human1.35580623
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.35507248
59* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34604205
60* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.33997532
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31149617
62* PIAS1_25552417_ChIP-Seq_VCAP_Human1.27465971
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27389192
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26637537
65TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23248695
66RING1B_27294783_Chip-Seq_NPCs_Mouse1.22273986
67KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.19372361
68SALL1_21062744_ChIP-ChIP_HESCs_Human1.18596663
69CBP_20019798_ChIP-Seq_JUKART_Human1.18193919
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18193919
71TAL1_26923725_Chip-Seq_HPCs_Mouse1.18032329
72FLI1_27457419_Chip-Seq_LIVER_Mouse1.17635755
73STAT3_23295773_ChIP-Seq_U87_Human1.17592076
74FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.17172167
75FUS_26573619_Chip-Seq_HEK293_Human1.15607342
76ARNT_22903824_ChIP-Seq_MCF-7_Human1.15409117
77AR_19668381_ChIP-Seq_PC3_Human1.15313547
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.15115672
79* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11955332
80* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11653467
81* ER_23166858_ChIP-Seq_MCF-7_Human1.09513705
82RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.09344254
83CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08918155
84AHR_22903824_ChIP-Seq_MCF-7_Human1.08649324
85DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08368303
86P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08050523
87TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07437226
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07437226
89RUNX2_22187159_ChIP-Seq_PCA_Human1.06962509
90CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06474434
91ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06085577
92* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06071859
93TCF4_23295773_ChIP-Seq_U87_Human1.06058282
94* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04466829
95KDM2B_26808549_Chip-Seq_REH_Human1.03908526
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.03672493
97JUN_21703547_ChIP-Seq_K562_Human1.03161708
98EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.01457244
99NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01428968
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01288816
101WT1_25993318_ChIP-Seq_PODOCYTE_Human1.00439819
102VDR_22108803_ChIP-Seq_LS180_Human0.99948100
103FLI1_21867929_ChIP-Seq_TH2_Mouse0.99776296
104* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99565180
105RBPJ_22232070_ChIP-Seq_NCS_Mouse0.99169894
106SOX9_26525672_Chip-Seq_HEART_Mouse0.98831400
107CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98233349
108TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97926635
109SMAD3_21741376_ChIP-Seq_ESCs_Human0.97818339
110CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97719832
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.97563838
112P53_22387025_ChIP-Seq_ESCs_Mouse0.97055013
113TP53_18474530_ChIP-ChIP_U2OS_Human0.95831857
114TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95094715
115TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93343326
116ZFP281_18757296_ChIP-ChIP_E14_Mouse0.92229093
117* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.92099202
118TP53_16413492_ChIP-PET_HCT116_Human0.90520455
119NANOG_18555785_Chip-Seq_ESCs_Mouse0.89714953
120SMAD4_21741376_ChIP-Seq_HESCs_Human0.87027903
121BCAT_22108803_ChIP-Seq_LS180_Human0.86998489
122RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.86637409

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.65600616
2MP0003880_abnormal_central_pattern5.55927266
3MP0003635_abnormal_synaptic_transmissio3.94453335
4MP0004270_analgesia3.71796360
5MP0002063_abnormal_learning/memory/cond3.33159193
6MP0009745_abnormal_behavioral_response3.22190693
7MP0005423_abnormal_somatic_nervous3.20906907
8MP0002064_seizures2.89718364
9MP0001968_abnormal_touch/_nociception2.88319604
10MP0002572_abnormal_emotion/affect_behav2.81048770
11MP0009046_muscle_twitch2.74043068
12MP0002734_abnormal_mechanical_nocicepti2.71817263
13MP0003136_yellow_coat_color2.65133607
14MP0006276_abnormal_autonomic_nervous2.64341621
15MP0000778_abnormal_nervous_system2.49539813
16MP0001486_abnormal_startle_reflex2.48454451
17MP0002272_abnormal_nervous_system2.38647272
18MP0002735_abnormal_chemical_nociception2.36101231
19MP0002822_catalepsy2.32013988
20MP0002736_abnormal_nociception_after2.28020697
21MP0002184_abnormal_innervation2.22834239
22MP0002653_abnormal_ependyma_morphology2.19163960
23MP0001440_abnormal_grooming_behavior2.17255198
24MP0001501_abnormal_sleep_pattern2.09673550
25MP0002733_abnormal_thermal_nociception2.08352645
26MP0002067_abnormal_sensory_capabilities2.03457753
27MP0002557_abnormal_social/conspecific_i1.94038406
28MP0001970_abnormal_pain_threshold1.93141274
29MP0001984_abnormal_olfaction1.81372029
30MP0001529_abnormal_vocalization1.81243640
31MP0004924_abnormal_behavior1.76212019
32MP0005386_behavior/neurological_phenoty1.76212019
33MP0004811_abnormal_neuron_physiology1.75511281
34MP0000955_abnormal_spinal_cord1.71975885
35MP0005645_abnormal_hypothalamus_physiol1.69698875
36MP0003122_maternal_imprinting1.68194693
37MP0002102_abnormal_ear_morphology1.64731212
38MP0009780_abnormal_chondrocyte_physiolo1.62921707
39MP0001905_abnormal_dopamine_level1.58925032
40MP0003329_amyloid_beta_deposits1.58890630
41MP0004858_abnormal_nervous_system1.54951467
42MP0008569_lethality_at_weaning1.54346468
43MP0002882_abnormal_neuron_morphology1.51534770
44MP0002909_abnormal_adrenal_gland1.43600088
45MP0002066_abnormal_motor_capabilities/c1.39904890
46MP0001188_hyperpigmentation1.39684242
47MP0003787_abnormal_imprinting1.38953439
48MP0004142_abnormal_muscle_tone1.37930918
49MP0002928_abnormal_bile_duct1.37461891
50MP0003879_abnormal_hair_cell1.35704967
51MP0003011_delayed_dark_adaptation1.33645644
52MP0004885_abnormal_endolymph1.30119677
53MP0005646_abnormal_pituitary_gland1.29809910
54MP0000569_abnormal_digit_pigmentation1.29070033
55MP0001502_abnormal_circadian_rhythm1.26871432
56MP0002152_abnormal_brain_morphology1.24460957
57MP0004133_heterotaxia1.23272162
58MP0008877_abnormal_DNA_methylation1.22356551
59MP0005253_abnormal_eye_physiology1.22336231
60MP0004742_abnormal_vestibular_system1.15682213
61MP0005084_abnormal_gallbladder_morpholo1.12739807
62MP0000631_abnormal_neuroendocrine_gland1.06356902
63MP0001986_abnormal_taste_sensitivity1.05993307
64MP0005499_abnormal_olfactory_system1.04641279
65MP0005394_taste/olfaction_phenotype1.04641279
66MP0000751_myopathy1.02207696
67MP0003633_abnormal_nervous_system1.01700752
68MP0005551_abnormal_eye_electrophysiolog0.99074712
69MP0008995_early_reproductive_senescence0.98648868
70MP0003631_nervous_system_phenotype0.96375808
71MP0000647_abnormal_sebaceous_gland0.93747496
72MP0002752_abnormal_somatic_nervous0.92946340
73MP0002069_abnormal_eating/drinking_beha0.92383601
74MP0005248_abnormal_Harderian_gland0.92148552
75MP0010386_abnormal_urinary_bladder0.90592169
76MP0004085_abnormal_heartbeat0.87708031
77MP0002277_abnormal_respiratory_mucosa0.87402473
78MP0002229_neurodegeneration0.86326729
79MP0001963_abnormal_hearing_physiology0.86098571
80MP0002751_abnormal_autonomic_nervous0.85538611
81MP0003634_abnormal_glial_cell0.85516378
82MP0005195_abnormal_posterior_eye0.82750494
83MP0003861_abnormal_nervous_system0.82211108
84MP0002837_dystrophic_cardiac_calcinosis0.81982497
85MP0002638_abnormal_pupillary_reflex0.81738515
86MP0000534_abnormal_ureter_morphology0.80560913
87MP0000049_abnormal_middle_ear0.79288821
88MP0004145_abnormal_muscle_electrophysio0.78726959
89MP0008872_abnormal_physiological_respon0.77683219
90MP0003632_abnormal_nervous_system0.77552099
91MP0003137_abnormal_impulse_conducting0.74742011
92MP0003890_abnormal_embryonic-extraembry0.74218850
93MP0005409_darkened_coat_color0.72838517
94MP0004233_abnormal_muscle_weight0.72781001
95MP0001177_atelectasis0.72229497
96MP0001299_abnormal_eye_distance/0.72205370
97MP0005171_absent_coat_pigmentation0.71703010
98MP0005187_abnormal_penis_morphology0.71227602
99MP0005535_abnormal_body_temperature0.69728344
100MP0003567_abnormal_fetal_cardiomyocyte0.68920928
101MP0005377_hearing/vestibular/ear_phenot0.68644668
102MP0003878_abnormal_ear_physiology0.68644668
103MP0001919_abnormal_reproductive_system0.68025630
104MP0002233_abnormal_nose_morphology0.67509576
105MP0006072_abnormal_retinal_apoptosis0.65853231
106MP0001664_abnormal_digestion0.65748776
107MP0008874_decreased_physiological_sensi0.65466350
108MP0005623_abnormal_meninges_morphology0.65206274
109MP0005391_vision/eye_phenotype0.64880923
110MP0001943_abnormal_respiration0.64046652
111MP0008789_abnormal_olfactory_epithelium0.63669871
112MP0004484_altered_response_of0.63490738
113MP0003121_genomic_imprinting0.63048774
114MP0000026_abnormal_inner_ear0.61973760
115MP0002160_abnormal_reproductive_system0.61770744
116MP0002876_abnormal_thyroid_physiology0.61767536
117MP0000013_abnormal_adipose_tissue0.60840667
118MP0004215_abnormal_myocardial_fiber0.60039951
119MP0000604_amyloidosis0.58697366
120MP0008961_abnormal_basal_metabolism0.58184304
121MP0002090_abnormal_vision0.57690057
122MP0002082_postnatal_lethality0.56202800
123MP0010770_preweaning_lethality0.56202800
124MP0001485_abnormal_pinna_reflex0.55833000
125MP0010769_abnormal_survival0.55016243
126MP0010768_mortality/aging0.51833739

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.70213090
2Myokymia (HP:0002411)5.81328406
3Focal seizures (HP:0007359)5.31483517
4Epileptic encephalopathy (HP:0200134)4.85897218
5Atonic seizures (HP:0010819)4.59198186
6Visual hallucinations (HP:0002367)4.51377225
7Febrile seizures (HP:0002373)4.31716388
8Medial flaring of the eyebrow (HP:0010747)4.16234716
9Congenital primary aphakia (HP:0007707)4.13778675
10Progressive cerebellar ataxia (HP:0002073)3.99420142
11Nephrogenic diabetes insipidus (HP:0009806)3.95654296
12Absence seizures (HP:0002121)3.92949032
13Broad-based gait (HP:0002136)3.89701373
14Supranuclear gaze palsy (HP:0000605)3.88650901
15Hyperventilation (HP:0002883)3.73375710
16Limb dystonia (HP:0002451)3.62665336
17Dialeptic seizures (HP:0011146)3.58287556
18Genital tract atresia (HP:0001827)3.52339810
19Vaginal atresia (HP:0000148)3.52124646
20Ulnar claw (HP:0001178)3.48155188
21True hermaphroditism (HP:0010459)3.38728387
22Amblyopia (HP:0000646)3.38425015
23Generalized tonic-clonic seizures (HP:0002069)3.35545154
24Excessive salivation (HP:0003781)3.28895189
25Drooling (HP:0002307)3.28895189
26Action tremor (HP:0002345)3.28211826
27Ankle clonus (HP:0011448)3.27159342
28Mutism (HP:0002300)3.21105947
29Polyphagia (HP:0002591)3.16836926
30Abnormal eating behavior (HP:0100738)3.04872516
31Impaired vibration sensation in the lower limbs (HP:0002166)3.04348437
32Pancreatic fibrosis (HP:0100732)3.03298845
33Abnormality of the corticospinal tract (HP:0002492)2.99553682
34Progressive inability to walk (HP:0002505)2.98583621
35Poor coordination (HP:0002370)2.95696842
36Truncal ataxia (HP:0002078)2.91367678
37Abnormality of midbrain morphology (HP:0002418)2.88705062
38Molar tooth sign on MRI (HP:0002419)2.88705062
39Poor eye contact (HP:0000817)2.86576023
40Pancreatic cysts (HP:0001737)2.84165359
41Pheochromocytoma (HP:0002666)2.81275014
42Depression (HP:0000716)2.79422317
43Urinary bladder sphincter dysfunction (HP:0002839)2.79220694
44Insidious onset (HP:0003587)2.72760436
45Termporal pattern (HP:0011008)2.72760436
46Epileptiform EEG discharges (HP:0011182)2.70508255
47Anxiety (HP:0000739)2.70484686
48Urinary urgency (HP:0000012)2.69920603
49Nephronophthisis (HP:0000090)2.68908331
50Gaze-evoked nystagmus (HP:0000640)2.67904416
51Amyotrophic lateral sclerosis (HP:0007354)2.64854292
52Dysdiadochokinesis (HP:0002075)2.63945825
53Abnormality of the lower motor neuron (HP:0002366)2.63901766
54Renal cortical cysts (HP:0000803)2.63043496
55Abnormal social behavior (HP:0012433)2.62169146
56Impaired social interactions (HP:0000735)2.62169146
57Failure to thrive in infancy (HP:0001531)2.57935474
58EEG with generalized epileptiform discharges (HP:0011198)2.57828019
59Agitation (HP:0000713)2.57038796
60Split foot (HP:0001839)2.55055227
61Spastic gait (HP:0002064)2.54308011
62Cerebral inclusion bodies (HP:0100314)2.51352846
63Abnormality of binocular vision (HP:0011514)2.50713511
64Diplopia (HP:0000651)2.50713511
65Neuroendocrine neoplasm (HP:0100634)2.50494145
66Cortical dysplasia (HP:0002539)2.50426476
67Pachygyria (HP:0001302)2.48853061
68Broad foot (HP:0001769)2.48807669
69Hypsarrhythmia (HP:0002521)2.45882717
70Genetic anticipation (HP:0003743)2.44770518
71Inability to walk (HP:0002540)2.44434685
72Hemiparesis (HP:0001269)2.43834652
73Torticollis (HP:0000473)2.41009056
74Gait imbalance (HP:0002141)2.40943238
75Hypoventilation (HP:0002791)2.40712073
76Dysmetria (HP:0001310)2.37577357
77Abnormality of the renal medulla (HP:0100957)2.35387104
78Papilledema (HP:0001085)2.33726591
79Impaired smooth pursuit (HP:0007772)2.33119023
80Fetal akinesia sequence (HP:0001989)2.31094554
81Neurofibrillary tangles (HP:0002185)2.30296196
82Aplasia/Hypoplasia of the lens (HP:0008063)2.30178915
83Postaxial hand polydactyly (HP:0001162)2.28408056
84Bradykinesia (HP:0002067)2.25053001
85Hemiplegia (HP:0002301)2.24686603
86Absent speech (HP:0001344)2.24627922
87Abnormality of the renal cortex (HP:0011035)2.24537816
88Stereotypic behavior (HP:0000733)2.23757000
89Aplasia/Hypoplasia of the brainstem (HP:0007362)2.23131816
90Hypoplasia of the brainstem (HP:0002365)2.23131816
91Postural instability (HP:0002172)2.22364371
92Scanning speech (HP:0002168)2.19891672
93Focal dystonia (HP:0004373)2.19141014
94Protruding tongue (HP:0010808)2.18433712
95Sclerocornea (HP:0000647)2.17987214
96Abnormality of salivation (HP:0100755)2.17887398
97Abnormal hair whorl (HP:0010721)2.17135837
98Intestinal atresia (HP:0011100)2.15496503
99Akinesia (HP:0002304)2.14611497
100Lower limb muscle weakness (HP:0007340)2.14120159
101Retinal dysplasia (HP:0007973)2.13679597
102Specific learning disability (HP:0001328)2.12541864
103Spastic tetraplegia (HP:0002510)2.09519641
104Blue irides (HP:0000635)2.08955648
105Inappropriate behavior (HP:0000719)2.07319841
106Optic nerve hypoplasia (HP:0000609)2.07213952
107Megalencephaly (HP:0001355)2.06958201
108Shoulder girdle muscle weakness (HP:0003547)2.06761382
109Congenital stationary night blindness (HP:0007642)2.06539004
110Exotropia (HP:0000577)2.06514395
111Poor suck (HP:0002033)2.04165334
112Craniofacial dystonia (HP:0012179)2.04063555
113Stomach cancer (HP:0012126)2.03771436
114Aqueductal stenosis (HP:0002410)2.01499206
115Abnormality of ocular smooth pursuit (HP:0000617)2.00776125
116Morphological abnormality of the pyramidal tract (HP:0002062)1.99395430
117Esotropia (HP:0000565)1.96407230
118Septo-optic dysplasia (HP:0100842)1.95863650
119Impaired vibratory sensation (HP:0002495)1.95709360
120Intention tremor (HP:0002080)1.93447717
121Aplasia/Hypoplasia of the tibia (HP:0005772)1.93321702
122Hyperthyroidism (HP:0000836)1.90796367
123Degeneration of the lateral corticospinal tracts (HP:0002314)1.90270238
124Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.90270238
125Lissencephaly (HP:0001339)1.89209264
126Left ventricular hypertrophy (HP:0001712)1.87944617
127Gastrointestinal atresia (HP:0002589)1.87768866
128Oligodactyly (hands) (HP:0001180)1.87522534
129Status epilepticus (HP:0002133)1.87108571
130Hypothermia (HP:0002045)1.87033229
131Labial hypoplasia (HP:0000066)1.86582309
132Decreased testicular size (HP:0008734)1.85346867
133Generalized hypotonia (HP:0001290)1.84043481
134Neoplasm of the peripheral nervous system (HP:0100007)1.83128712
135Sleep apnea (HP:0010535)1.82580379
136Incomplete penetrance (HP:0003829)1.82199039
137Anophthalmia (HP:0000528)1.82136803
138Abnormality of the labia minora (HP:0012880)1.81652710
139Short foot (HP:0001773)1.81602772
140Chronic hepatic failure (HP:0100626)1.81472052
141Narrow nasal bridge (HP:0000446)1.79119557
142Gait ataxia (HP:0002066)1.77747165
143Narrow forehead (HP:0000341)1.77716831
144Short tibia (HP:0005736)1.73936538
145Cystic liver disease (HP:0006706)1.73276890
146Abnormal ciliary motility (HP:0012262)1.72067740
147Abnormal respiratory epithelium morphology (HP:0012253)1.71872332
148Abnormal respiratory motile cilium morphology (HP:0005938)1.71872332
149Occipital encephalocele (HP:0002085)1.71369833
150Postaxial foot polydactyly (HP:0001830)1.70320092
151Hypoplasia of the corpus callosum (HP:0002079)1.70120499

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.88908320
2NTRK33.79037548
3EPHA43.65382053
4CASK3.35772726
5MAP3K93.29906234
6MAP3K43.03561034
7MINK12.85153146
8MAP2K72.77579841
9NTRK22.59656173
10EPHA32.50545760
11MAP3K122.44494511
12PINK12.41653080
13DAPK22.15968382
14MAPK131.98709346
15MAPK151.94180319
16MAP2K41.84731588
17KSR11.79079767
18PAK61.76838401
19PLK21.68267047
20SIK21.63106992
21MAP4K21.60367159
22TNIK1.60081016
23DYRK31.55322468
24CDK51.48464282
25DAPK11.46438775
26FRK1.46182252
27TXK1.44450544
28PHKG21.44122202
29PHKG11.44122202
30CDK191.43275029
31KSR21.39689661
32PNCK1.38594526
33ADRBK21.36710759
34NTRK11.36046116
35TSSK61.35083769
36BMPR1B1.34596518
37GRK51.33524765
38PRPF4B1.30676386
39UHMK11.26990547
40CAMKK11.21624125
41PRKCG1.19641125
42ERBB31.18753701
43RIPK41.14788780
44DYRK21.14157310
45CSNK1G21.08752462
46CAMK2A1.02214414
47BCR1.00443076
48CDK180.99999601
49CDK140.94106099
50TYRO30.93707505
51CDK150.93437887
52DYRK1A0.92605049
53ARAF0.91611944
54SGK2230.91357322
55SGK4940.91357322
56CAMKK20.90100140
57PAK30.89871333
58RPS6KA40.89027733
59PRKD30.86098276
60EPHB10.84036312
61SIK30.83504936
62TAOK10.82379656
63CAMK2B0.81796292
64CDK11A0.81065482
65FES0.80671595
66LATS20.80479334
67TRIM280.80067288
68WNK30.79218705
69OXSR10.75682697
70RET0.74487370
71DYRK1B0.73524057
72SGK20.72480403
73AKT30.70580129
74CSNK1G30.69939267
75INSRR0.68099396
76MAP3K20.67688747
77LIMK10.66128729
78FGFR20.63639264
79PRKCZ0.62483694
80CAMK10.62476401
81MARK20.62150365
82BCKDK0.62113644
83PTK2B0.61473929
84GRK10.60516944
85STK380.59331180
86PRKCE0.58942726
87STK110.58011127
88FGR0.57182326
89SGK10.57157771
90PRKACA0.55505715
91CCNB10.54914848
92LMTK20.54278436
93RPS6KA20.53344630
94PRKG10.52317234
95CDK30.51984686
96BMPR20.50985639
97FER0.50370292
98PKN10.49877249
99CAMK1G0.46985925
100NME10.46185152
101GRK70.45916738
102MAP3K60.44827501
103SGK30.43917520
104ADRBK10.43553920
105FYN0.43481477
106RAF10.42992298
107CSNK1A1L0.42826086
108PRKCH0.42799794
109RPS6KA30.41403544
110RPS6KA50.41037869
111WEE10.40766744
112CAMK40.40184555
113ACVR1B0.40110941
114ROCK20.39863811
115CAMK2D0.39373065
116STK38L0.39040633
117CSNK1G10.38182468
118MAPK120.38030663
119PASK0.37692929
120CDC42BPA0.37558067
121MAP2K10.36544469
122MAP3K130.36197822
123PRKACB0.36188769
124TAOK30.36009489
125VRK10.35747879
126NEK10.34329250
127IRAK10.33505319
128MAPK90.31857724
129PRKCB0.31773697
130PDK10.31272543
131MKNK20.30914318
132EPHB20.30815766
133WNK40.30742093
134CSNK1D0.30358000
135CAMK2G0.30212785
136ERBB20.30115360
137MAPK100.29819008
138PDPK10.29606241
139PRKCA0.28882955

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.10985173
2Synaptic vesicle cycle_Homo sapiens_hsa047213.39807031
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.78699759
4GABAergic synapse_Homo sapiens_hsa047272.75985213
5Circadian entrainment_Homo sapiens_hsa047132.65141173
6Olfactory transduction_Homo sapiens_hsa047402.62500821
7Morphine addiction_Homo sapiens_hsa050322.54296181
8Glutamatergic synapse_Homo sapiens_hsa047242.52973691
9Long-term potentiation_Homo sapiens_hsa047202.49473235
10Amphetamine addiction_Homo sapiens_hsa050312.34894593
11Dopaminergic synapse_Homo sapiens_hsa047282.27738956
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.01951341
13Salivary secretion_Homo sapiens_hsa049701.97753902
14Cholinergic synapse_Homo sapiens_hsa047251.92031282
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.87958729
16Insulin secretion_Homo sapiens_hsa049111.84779021
17Taste transduction_Homo sapiens_hsa047421.82938641
18Collecting duct acid secretion_Homo sapiens_hsa049661.82188793
19Serotonergic synapse_Homo sapiens_hsa047261.81650347
20Long-term depression_Homo sapiens_hsa047301.76366793
21Renin secretion_Homo sapiens_hsa049241.75324686
22Cocaine addiction_Homo sapiens_hsa050301.73789502
23Gastric acid secretion_Homo sapiens_hsa049711.67616265
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.65924948
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.63024806
26Axon guidance_Homo sapiens_hsa043601.61026316
27Protein export_Homo sapiens_hsa030601.58282288
28Oxytocin signaling pathway_Homo sapiens_hsa049211.53716277
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.53580720
30Butanoate metabolism_Homo sapiens_hsa006501.53510831
31Gap junction_Homo sapiens_hsa045401.48892437
32Calcium signaling pathway_Homo sapiens_hsa040201.45486564
33GnRH signaling pathway_Homo sapiens_hsa049121.32838807
34Vibrio cholerae infection_Homo sapiens_hsa051101.28989381
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.28692555
36Nitrogen metabolism_Homo sapiens_hsa009101.25018353
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23633534
38Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.22592703
39Steroid biosynthesis_Homo sapiens_hsa001001.20500464
40Phototransduction_Homo sapiens_hsa047441.18551462
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.16121503
42ErbB signaling pathway_Homo sapiens_hsa040121.12256368
43cAMP signaling pathway_Homo sapiens_hsa040241.11553765
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.08543408
45Estrogen signaling pathway_Homo sapiens_hsa049151.06603131
46Glioma_Homo sapiens_hsa052141.05510767
47Maturity onset diabetes of the young_Homo sapiens_hsa049501.05291635
48Cardiac muscle contraction_Homo sapiens_hsa042601.05163902
49Melanogenesis_Homo sapiens_hsa049161.04759054
50Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.98876464
51Type II diabetes mellitus_Homo sapiens_hsa049300.97002690
52cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90264429
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88804590
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.87425460
55Oocyte meiosis_Homo sapiens_hsa041140.86396988
56Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.86299204
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.74209383
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74189032
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73979373
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73490768
61Alzheimers disease_Homo sapiens_hsa050100.72244755
62Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.71946846
63Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.71474078
64Alcoholism_Homo sapiens_hsa050340.70438544
65Regulation of autophagy_Homo sapiens_hsa041400.70034964
66MAPK signaling pathway_Homo sapiens_hsa040100.68227343
67Oxidative phosphorylation_Homo sapiens_hsa001900.67171415
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.67090717
69Propanoate metabolism_Homo sapiens_hsa006400.66449476
70Dilated cardiomyopathy_Homo sapiens_hsa054140.66212362
71Ether lipid metabolism_Homo sapiens_hsa005650.65906714
72Linoleic acid metabolism_Homo sapiens_hsa005910.65719153
73Dorso-ventral axis formation_Homo sapiens_hsa043200.64828761
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.64562051
75Pancreatic secretion_Homo sapiens_hsa049720.63981238
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.62299467
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60576710
78Thyroid hormone synthesis_Homo sapiens_hsa049180.60300180
79Choline metabolism in cancer_Homo sapiens_hsa052310.59801438
80Endometrial cancer_Homo sapiens_hsa052130.58960696
81Ras signaling pathway_Homo sapiens_hsa040140.57477440
82beta-Alanine metabolism_Homo sapiens_hsa004100.56790381
83Basal transcription factors_Homo sapiens_hsa030220.56279605
84Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.56013564
85Basal cell carcinoma_Homo sapiens_hsa052170.55310188
86Renal cell carcinoma_Homo sapiens_hsa052110.53765051
87Primary bile acid biosynthesis_Homo sapiens_hsa001200.53749017
88Parkinsons disease_Homo sapiens_hsa050120.53537489
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.53162806
90Colorectal cancer_Homo sapiens_hsa052100.52262398
91Wnt signaling pathway_Homo sapiens_hsa043100.51991316
92Glucagon signaling pathway_Homo sapiens_hsa049220.51686567
93Rap1 signaling pathway_Homo sapiens_hsa040150.51115407
94VEGF signaling pathway_Homo sapiens_hsa043700.49943301
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48899220
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48253245
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47862533
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.47129430
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46798744
100Hippo signaling pathway_Homo sapiens_hsa043900.45379509
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45102163
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44345892
103Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41080270
104Prion diseases_Homo sapiens_hsa050200.40706758
105mTOR signaling pathway_Homo sapiens_hsa041500.40521565
106Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40464959
107Fanconi anemia pathway_Homo sapiens_hsa034600.40194537
108Endocytosis_Homo sapiens_hsa041440.39998866
109Circadian rhythm_Homo sapiens_hsa047100.38925603
110Insulin signaling pathway_Homo sapiens_hsa049100.38456557
111Phagosome_Homo sapiens_hsa041450.36809743
112Fatty acid biosynthesis_Homo sapiens_hsa000610.36143870
113Non-small cell lung cancer_Homo sapiens_hsa052230.36064222
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35538313
115Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35271111
116Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34690062
117Type I diabetes mellitus_Homo sapiens_hsa049400.33676877
118Ovarian steroidogenesis_Homo sapiens_hsa049130.33199639
119Bile secretion_Homo sapiens_hsa049760.32985567
120Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.32883482
121Hedgehog signaling pathway_Homo sapiens_hsa043400.31937844
122Rheumatoid arthritis_Homo sapiens_hsa053230.30970084
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.30500916
124Inositol phosphate metabolism_Homo sapiens_hsa005620.30092546
125Huntingtons disease_Homo sapiens_hsa050160.30028895
126Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.29745096
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28558307
128Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.28236725

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