LRRC59

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1folic acid-containing compound biosynthetic process (GO:0009396)4.89535738
2DNA unwinding involved in DNA replication (GO:0006268)4.56336030
3formation of translation preinitiation complex (GO:0001731)4.29073534
4regulation of translational fidelity (GO:0006450)4.21337341
5protein localization to kinetochore (GO:0034501)4.15381477
6mitotic nuclear envelope disassembly (GO:0007077)4.02665842
7Golgi transport vesicle coating (GO:0048200)4.01305178
8COPI coating of Golgi vesicle (GO:0048205)4.01305178
9heterochromatin organization (GO:0070828)3.92436168
10nuclear pore organization (GO:0006999)3.87476848
11membrane disassembly (GO:0030397)3.83153827
12nuclear envelope disassembly (GO:0051081)3.83153827
13nuclear pore complex assembly (GO:0051292)3.80435231
14retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.79264646
15protein localization to endosome (GO:0036010)3.76518047
16regulation of translational termination (GO:0006449)3.73510604
17IMP biosynthetic process (GO:0006188)3.67881611
18nucleobase biosynthetic process (GO:0046112)3.60949505
19nucleobase-containing small molecule interconversion (GO:0015949)3.44931355
20regulation of mammary gland epithelial cell proliferation (GO:0033599)3.43947830
21hemidesmosome assembly (GO:0031581)3.43239545
22ribosome assembly (GO:0042255)3.39171774
23protein localization to chromosome, centromeric region (GO:0071459)3.33283071
24skin morphogenesis (GO:0043589)3.30051805
25cellular protein complex localization (GO:0034629)3.29335545
26cell adhesion mediated by integrin (GO:0033627)3.28248294
27IMP metabolic process (GO:0046040)3.28144508
28cell-substrate junction assembly (GO:0007044)3.27346831
29regulation of early endosome to late endosome transport (GO:2000641)3.26965065
30protein maturation by protein folding (GO:0022417)3.23073457
31nuclear envelope organization (GO:0006998)3.21468676
32protein complex localization (GO:0031503)3.21441802
33DNA replication initiation (GO:0006270)3.20965167
34adherens junction assembly (GO:0034333)3.20411268
35cell-substrate adherens junction assembly (GO:0007045)3.17738774
36focal adhesion assembly (GO:0048041)3.17738774
37folic acid metabolic process (GO:0046655)3.17421032
38DNA strand elongation involved in DNA replication (GO:0006271)3.16096125
39purine nucleobase biosynthetic process (GO:0009113)3.13665717
40regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.12200123
41vesicle coating (GO:0006901)3.08250125
42COPII vesicle coating (GO:0048208)3.06949956
43activation of Rac GTPase activity (GO:0032863)3.06896621
44desmosome organization (GO:0002934)3.01816297
45DNA duplex unwinding (GO:0032508)2.99955655
46regulation of spindle organization (GO:0090224)2.99110821
47mitotic G1 DNA damage checkpoint (GO:0031571)2.96940937
48DNA geometric change (GO:0032392)2.96805301
49DNA strand elongation (GO:0022616)2.96670751
50DNA replication-dependent nucleosome assembly (GO:0006335)2.96540505
51DNA replication-dependent nucleosome organization (GO:0034723)2.96540505
52positive regulation of nuclease activity (GO:0032075)2.91708971
53positive regulation of SMAD protein import into nucleus (GO:0060391)2.89480222
54glucocorticoid receptor signaling pathway (GO:0042921)2.88992413
55activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.88836321
56pore complex assembly (GO:0046931)2.88015132
57regulation of protein heterodimerization activity (GO:0043497)2.87099948
58basement membrane organization (GO:0071711)2.86158209
59sister chromatid segregation (GO:0000819)2.86078836
60regulation of posttranscriptional gene silencing (GO:0060147)2.85141115
61regulation of gene silencing by miRNA (GO:0060964)2.85141115
62regulation of gene silencing by RNA (GO:0060966)2.85141115
63chromosome condensation (GO:0030261)2.84406045
64mitotic metaphase plate congression (GO:0007080)2.82802218
65tetrahydrofolate metabolic process (GO:0046653)2.82336787
66protein export from nucleus (GO:0006611)2.82236696
67positive regulation of chromosome segregation (GO:0051984)2.81905117
68maternal placenta development (GO:0001893)2.80738660
69ER-nucleus signaling pathway (GO:0006984)2.79106857
70mitotic sister chromatid segregation (GO:0000070)2.78992939
71regulation of hippo signaling (GO:0035330)2.78842444
72regulation of nucleobase-containing compound transport (GO:0032239)2.77941838
73nuclear envelope reassembly (GO:0031468)2.77276652
74mitotic nuclear envelope reassembly (GO:0007084)2.77276652
75regulation of RNA export from nucleus (GO:0046831)2.76848989
76pinocytosis (GO:0006907)2.76199195
77maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.73282990
78regulation of glucose import in response to insulin stimulus (GO:2001273)2.73275926
79regulation of SMAD protein import into nucleus (GO:0060390)2.73023137
80hippo signaling (GO:0035329)2.72755706
813-UTR-mediated mRNA stabilization (GO:0070935)2.72747068
82regulation of nuclease activity (GO:0032069)2.72407031
83epithelial cell-cell adhesion (GO:0090136)2.72078892
84dosage compensation (GO:0007549)2.68918806
85regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.68877061
86protein localization to microtubule (GO:0035372)2.68222342
87negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.68051168
88histone-serine phosphorylation (GO:0035404)2.67433804
89RNA stabilization (GO:0043489)2.66666427
90mRNA stabilization (GO:0048255)2.66666427
91pentose-phosphate shunt (GO:0006098)2.66153166
92proline metabolic process (GO:0006560)2.65925291
93ribosome biogenesis (GO:0042254)2.65797762
94regulation of mitotic spindle organization (GO:0060236)2.64257226
95peptidyl-arginine omega-N-methylation (GO:0035247)2.63187275
96chromatin assembly (GO:0031497)2.62027497
97peptidyl-proline hydroxylation (GO:0019511)2.61928424
98regulation of translational elongation (GO:0006448)2.61341361
99pre-miRNA processing (GO:0031054)2.61058696
100translational initiation (GO:0006413)2.60485917
101DNA replication checkpoint (GO:0000076)2.60241495
102regulation of sister chromatid cohesion (GO:0007063)2.59893565
103glucose 6-phosphate metabolic process (GO:0051156)2.58950289
104mitotic G1/S transition checkpoint (GO:0044819)2.58516210
105establishment of integrated proviral latency (GO:0075713)2.57467190
106embryonic process involved in female pregnancy (GO:0060136)2.57376657
107polarized epithelial cell differentiation (GO:0030859)2.57126274
108negative regulation of cell size (GO:0045792)2.56912513
109trophectodermal cell differentiation (GO:0001829)2.56442194
110endoplasmic reticulum unfolded protein response (GO:0030968)2.56211109
111barbed-end actin filament capping (GO:0051016)2.56163034
112folic acid-containing compound metabolic process (GO:0006760)2.55140918
113pteridine-containing compound biosynthetic process (GO:0042559)2.54972089
114cytoskeletal anchoring at plasma membrane (GO:0007016)2.54794088
115establishment of apical/basal cell polarity (GO:0035089)2.51614895
116chaperone-mediated protein complex assembly (GO:0051131)2.51560264
117maturation of SSU-rRNA (GO:0030490)2.51285007
118interferon-gamma secretion (GO:0072643)2.51147999
119positive regulation of DNA-dependent DNA replication (GO:2000105)2.50181166
120nucleotide-sugar biosynthetic process (GO:0009226)2.49994435
121protein retention in ER lumen (GO:0006621)2.47749977
122mitotic chromosome condensation (GO:0007076)2.46955603
123telomere maintenance via semi-conservative replication (GO:0032201)2.46085442
124paraxial mesoderm development (GO:0048339)2.45615966
125protein hydroxylation (GO:0018126)2.44968521
126cellular response to unfolded protein (GO:0034620)2.44881710
127protein localization to chromosome (GO:0034502)2.44681035
128cellular response to topologically incorrect protein (GO:0035967)2.43190438
129negative regulation of fatty acid transport (GO:2000192)2.42523373
130mitotic sister chromatid cohesion (GO:0007064)2.42338536
131branching involved in mammary gland duct morphogenesis (GO:0060444)2.42116190
132T cell apoptotic process (GO:0070231)2.41797373
133glucose catabolic process (GO:0006007)2.41563958
134positive regulation of blood vessel endothelial cell migration (GO:0043536)2.41559352
135regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.41089746
136spindle assembly involved in mitosis (GO:0090307)2.39128157
137planar cell polarity pathway involved in neural tube closure (GO:0090179)2.38774493
138G1 DNA damage checkpoint (GO:0044783)2.38465938
139spliceosomal tri-snRNP complex assembly (GO:0000244)2.38216136
140negative regulation of RNA splicing (GO:0033119)2.37091974
141translesion synthesis (GO:0019985)2.36880286
142proline biosynthetic process (GO:0006561)2.35999624
143tRNA aminoacylation for protein translation (GO:0006418)2.35429093
144mammary gland epithelial cell proliferation (GO:0033598)2.35029100
145NADPH regeneration (GO:0006740)2.34518701
146negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.33794096
147histone H2A monoubiquitination (GO:0035518)2.33611139
148regulation of translational initiation (GO:0006446)2.32942441
149DNA packaging (GO:0006323)2.32934945
150dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.32744353
151apoptotic process involved in morphogenesis (GO:0060561)2.31514940

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.66672182
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.85199172
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.51958020
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.44237237
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.34766629
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.53407245
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.52549676
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.42361959
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.40976516
10MYC_22102868_ChIP-Seq_BL_Human2.35077409
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.23741864
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.16644250
13AR_21909140_ChIP-Seq_LNCAP_Human2.15280727
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.03244277
15NELFA_20434984_ChIP-Seq_ESCs_Mouse1.95774155
16TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.93093974
17XRN2_22483619_ChIP-Seq_HELA_Human1.83519721
18POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.71323705
19E2F1_21310950_ChIP-Seq_MCF-7_Human1.69914071
20STAT3_1855785_ChIP-Seq_MESCs_Mouse1.67676313
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.66599005
22ETS1_20019798_ChIP-Seq_JURKAT_Human1.64834358
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.61463956
24* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.60551515
25CREB1_15753290_ChIP-ChIP_HEK293T_Human1.59076259
26ZFX_18555785_ChIP-Seq_MESCs_Mouse1.57495539
27ZNF263_19887448_ChIP-Seq_K562_Human1.56865283
28CLOCK_20551151_ChIP-Seq_293T_Human1.56126701
29KLF4_18555785_ChIP-Seq_MESCs_Mouse1.53286739
30DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.52721999
31LXR_22292898_ChIP-Seq_THP-1_Human1.52387531
32SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.52003114
33VDR_21846776_ChIP-Seq_THP-1_Human1.51606512
34* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.50181591
35ATF3_27146783_Chip-Seq_COLON_Human1.48176279
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44718754
37TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44496552
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.43138624
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.42952247
40GABP_19822575_ChIP-Seq_HepG2_Human1.42820919
41* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.42211645
42DCP1A_22483619_ChIP-Seq_HELA_Human1.41922431
43SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.41495717
44TFEB_21752829_ChIP-Seq_HELA_Human1.39924578
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.39018331
46EST1_17652178_ChIP-ChIP_JURKAT_Human1.38504815
47HIF1A_21447827_ChIP-Seq_MCF-7_Human1.38271361
48KDM5A_27292631_Chip-Seq_BREAST_Human1.37963963
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.37919924
50KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.35129952
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.33897317
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.33716469
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32433724
54ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.31739976
55RARG_19884340_ChIP-ChIP_MEFs_Mouse1.30800846
56PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.30068830
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.28186254
58GABP_17652178_ChIP-ChIP_JURKAT_Human1.27141717
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.26042066
60* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.25038233
61SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.24355469
62* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.24054812
63TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.23651469
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.20730378
65TTF2_22483619_ChIP-Seq_HELA_Human1.20680471
66MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.20104882
67ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20100427
68RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.18370532
69UBF1/2_26484160_Chip-Seq_HMECs_Human1.18166089
70UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.17259029
71* CIITA_25753668_ChIP-Seq_RAJI_Human1.17018176
72VDR_23849224_ChIP-Seq_CD4+_Human1.16425156
73SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.15820213
74PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.15585995
75KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.14761794
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.14735693
77SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.14396694
78SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.13833865
79SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.13833865
80* CHD1_26751641_Chip-Seq_LNCaP_Human1.11901143
81PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.11623513
82CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.11290047
83WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09821166
84TCF3_18692474_ChIP-Seq_MEFs_Mouse1.09479168
85KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.09468241
86NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.07693484
87TCF7_22412390_ChIP-Seq_EML_Mouse1.07085840
88FOXP3_21729870_ChIP-Seq_TREG_Human1.06863981
89* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.06590820
90ESR2_21235772_ChIP-Seq_MCF-7_Human1.06559378
91KDM2B_26808549_Chip-Seq_SUP-B15_Human1.06163372
92NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.05993096
93RACK7_27058665_Chip-Seq_MCF-7_Human1.05573858
94CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.05031545
95MYB_21317192_ChIP-Seq_ERMYB_Mouse1.04865530
96THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04689857
97TRIM28_21343339_ChIP-Seq_HEK293_Human1.04068389
98TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03960982
99KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.03777486
100TET1_21451524_ChIP-Seq_MESCs_Mouse1.03654136
101P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03281432
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02753119
103* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02281809
104SRY_22984422_ChIP-ChIP_TESTIS_Rat1.02055904
105ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.00250060
106* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.98653127
107* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98624638
108HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98502161
109NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.98278738
110NANOG_21062744_ChIP-ChIP_HESCs_Human0.98223185
111HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.97906628
112EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.97394649
113SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.96515013
114CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96191715
115ZFP281_18757296_ChIP-ChIP_E14_Mouse0.95722626
116KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.95644811
117KDM2B_26808549_Chip-Seq_DND41_Human0.95231550
118NCOR1_26117541_ChIP-Seq_K562_Human0.93324290
119TBX5_21415370_ChIP-Seq_HL-1_Mouse0.93086910
120MAF_26560356_Chip-Seq_TH1_Human0.92533284
121UTX_26944678_Chip-Seq_JUKART_Human0.92498771
122KDM2B_26808549_Chip-Seq_K562_Human0.92263790
123* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92113938
124TP53_22127205_ChIP-Seq_IMR90_Human0.91505571
125OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89656591
126ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.88659952

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.06083143
2MP0010352_gastrointestinal_tract_polyps3.71413196
3MP0003693_abnormal_embryo_hatching3.44249947
4MP0004957_abnormal_blastocyst_morpholog2.83705639
5MP0008438_abnormal_cutaneous_collagen2.76188364
6MP0003111_abnormal_nucleus_morphology2.65967159
7MP0005451_abnormal_body_composition2.51835718
8MP0005076_abnormal_cell_differentiation2.48437018
9MP0003566_abnormal_cell_adhesion2.30663294
10MP0003077_abnormal_cell_cycle2.20756031
11MP0001730_embryonic_growth_arrest2.10210942
12MP0010094_abnormal_chromosome_stability2.10044262
13MP0006054_spinal_hemorrhage2.04609551
14MP0010307_abnormal_tumor_latency1.99143673
15MP0000537_abnormal_urethra_morphology1.83081965
16MP0000350_abnormal_cell_proliferation1.82150112
17MP0009053_abnormal_anal_canal1.79288168
18MP0010234_abnormal_vibrissa_follicle1.76621942
19MP0005023_abnormal_wound_healing1.75423473
20MP0002877_abnormal_melanocyte_morpholog1.74119487
21MP0003950_abnormal_plasma_membrane1.67732876
22MP0003123_paternal_imprinting1.66979501
23MP0005058_abnormal_lysosome_morphology1.66610978
24MP0003941_abnormal_skin_development1.65825000
25MP0002796_impaired_skin_barrier1.64407263
26MP0004197_abnormal_fetal_growth/weight/1.64078027
27MP0005380_embryogenesis_phenotype1.60269232
28MP0001672_abnormal_embryogenesis/_devel1.60269232
29MP0003984_embryonic_growth_retardation1.58166765
30MP0001697_abnormal_embryo_size1.57809479
31MP0002086_abnormal_extraembryonic_tissu1.57764470
32MP0004264_abnormal_extraembryonic_tissu1.57290287
33MP0008007_abnormal_cellular_replicative1.57011671
34MP0002088_abnormal_embryonic_growth/wei1.56384848
35MP0010030_abnormal_orbit_morphology1.51521762
36MP0005275_abnormal_skin_tensile1.51355545
37MP0008932_abnormal_embryonic_tissue1.50942534
38MP0000490_abnormal_crypts_of1.50368139
39MP0002084_abnormal_developmental_patter1.45701275
40MP0002080_prenatal_lethality1.45578399
41MP0009840_abnormal_foam_cell1.44061532
42MP0002396_abnormal_hematopoietic_system1.43104162
43MP0002085_abnormal_embryonic_tissue1.37989078
44MP0005409_darkened_coat_color1.37190819
45MP0000733_abnormal_muscle_development1.32813196
46MP0003191_abnormal_cellular_cholesterol1.32543803
47MP0005623_abnormal_meninges_morphology1.31877315
48MP0008057_abnormal_DNA_replication1.31205329
49MP0003300_gastrointestinal_ulcer1.29303663
50MP0001849_ear_inflammation1.27551328
51MP0004185_abnormal_adipocyte_glucose1.26975877
52MP0004858_abnormal_nervous_system1.26067734
53MP0000678_abnormal_parathyroid_gland1.25769603
54MP0001348_abnormal_lacrimal_gland1.25442891
55MP0004808_abnormal_hematopoietic_stem1.24284148
56MP0008260_abnormal_autophagy1.24140884
57MP0000003_abnormal_adipose_tissue1.23671862
58MP0001915_intracranial_hemorrhage1.22665977
59MP0003806_abnormal_nucleotide_metabolis1.21350174
60MP0003091_abnormal_cell_migration1.21234312
61MP0009278_abnormal_bone_marrow1.21060885
62MP0000858_altered_metastatic_potential1.20950438
63MP0001216_abnormal_epidermal_layer1.19846717
64MP0004272_abnormal_basement_membrane1.19806559
65MP0003279_aneurysm1.13896517
66MP0000762_abnormal_tongue_morphology1.12468791
67MP0003567_abnormal_fetal_cardiomyocyte1.11051060
68MP0001661_extended_life_span1.07165271
69MP0004233_abnormal_muscle_weight1.05712606
70MP0002019_abnormal_tumor_incidence1.04513833
71MP0000467_abnormal_esophagus_morphology1.02763154
72MP0003221_abnormal_cardiomyocyte_apopto0.98968987
73MP0003119_abnormal_digestive_system0.98399435
74MP0001545_abnormal_hematopoietic_system0.97554470
75MP0005397_hematopoietic_system_phenotyp0.97554470
76MP0003303_peritoneal_inflammation0.95141291
77MP0000313_abnormal_cell_death0.93662124
78MP0000428_abnormal_craniofacial_morphol0.93252525
79MP0010368_abnormal_lymphatic_system0.92436218
80MP0004782_abnormal_surfactant_physiolog0.92148550
81MP0005503_abnormal_tendon_morphology0.91386974
82MP0002111_abnormal_tail_morphology0.90397086
83MP0000358_abnormal_cell_content/0.89897640
84MP0000477_abnormal_intestine_morphology0.89675876
85MP0009672_abnormal_birth_weight0.88718498
86MP0003385_abnormal_body_wall0.88346031
87MP0002060_abnormal_skin_morphology0.88325509
88MP0003283_abnormal_digestive_organ0.87848795
89MP0005621_abnormal_cell_physiology0.87073257
90MP0003115_abnormal_respiratory_system0.85913707
91MP0009333_abnormal_splenocyte_physiolog0.85589951
92MP0005375_adipose_tissue_phenotype0.85536570
93MP0000767_abnormal_smooth_muscle0.85499455
94MP0000579_abnormal_nail_morphology0.84612723
95MP0003315_abnormal_perineum_morphology0.84347544
96MP0001881_abnormal_mammary_gland0.84259810
97MP0008058_abnormal_DNA_repair0.81917702
98MP0002089_abnormal_postnatal_growth/wei0.81842681
99MP0005257_abnormal_intraocular_pressure0.79345110
100MP0002098_abnormal_vibrissa_morphology0.79326549
101MP0001958_emphysema0.79288092
102MP0001293_anophthalmia0.78764442
103MP0003890_abnormal_embryonic-extraembry0.78708068
104MP0000534_abnormal_ureter_morphology0.78482846
105MP0009931_abnormal_skin_appearance0.78360153
106MP0002925_abnormal_cardiovascular_devel0.77724929
107MP0002896_abnormal_bone_mineralization0.77683085
108MP0009703_decreased_birth_body0.77595532
109MP0003453_abnormal_keratinocyte_physiol0.77385612
110MP0005384_cellular_phenotype0.77283983
111MP0003448_altered_tumor_morphology0.76919965
112MP0002282_abnormal_trachea_morphology0.75715089
113MP0005197_abnormal_uvea_morphology0.75191506
114MP0009697_abnormal_copulation0.75043131
115MP0003942_abnormal_urinary_system0.74893809
116MP0002092_abnormal_eye_morphology0.74123688
117MP0010771_integument_phenotype0.73695653
118MP0005666_abnormal_adipose_tissue0.73683695
119MP0001243_abnormal_dermal_layer0.72271495
120MP0000598_abnormal_liver_morphology0.71751580
121MP0004947_skin_inflammation0.71624599
122MP0005508_abnormal_skeleton_morphology0.71490650
123MP0000750_abnormal_muscle_regeneration0.71153377
124MP0002697_abnormal_eye_size0.71144510
125MP0005220_abnormal_exocrine_pancreas0.71079309
126MP0001666_abnormal_nutrient_absorption0.68282984
127MP0005501_abnormal_skin_physiology0.68143610
128MP0008770_decreased_survivor_rate0.67882596
129MP0000627_abnormal_mammary_gland0.65446437
130MP0009384_cardiac_valve_regurgitation0.65038080
131MP0005083_abnormal_biliary_tract0.64163209
132MP0000432_abnormal_head_morphology0.62714126

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.82072945
2Premature rupture of membranes (HP:0001788)4.16331265
3Ankle contracture (HP:0006466)3.18202425
4Selective tooth agenesis (HP:0001592)3.13186490
5Cerebral aneurysm (HP:0004944)3.11054188
6Genu recurvatum (HP:0002816)3.00103220
7Cervical subluxation (HP:0003308)2.93047226
8Shallow orbits (HP:0000586)2.87525305
9Distal lower limb amyotrophy (HP:0008944)2.70809871
10Asymmetry of the thorax (HP:0001555)2.70676160
11Spinal rigidity (HP:0003306)2.64616122
12Ankyloglossia (HP:0010296)2.60087252
13Insomnia (HP:0100785)2.56281837
14Degeneration of anterior horn cells (HP:0002398)2.55096024
15Abnormality of the anterior horn cell (HP:0006802)2.55096024
16Deviation of the thumb (HP:0009603)2.54458073
17Hand muscle atrophy (HP:0009130)2.53302544
18Peritonitis (HP:0002586)2.49152949
19Multiple enchondromatosis (HP:0005701)2.47829053
20Elbow flexion contracture (HP:0002987)2.44459310
21Abnormality of oral frenula (HP:0000190)2.43340875
22Trismus (HP:0000211)2.38153495
23Ependymoma (HP:0002888)2.34737494
24Increased density of long bones (HP:0006392)2.34426138
25Abnormality of the calcaneus (HP:0008364)2.34333483
26Dilatation of the ascending aorta (HP:0005111)2.34090946
27Upper limb amyotrophy (HP:0009129)2.32489210
28Distal upper limb amyotrophy (HP:0007149)2.32489210
29Ulnar bowing (HP:0003031)2.31131613
30Disproportionate tall stature (HP:0001519)2.29461037
31Proximal placement of thumb (HP:0009623)2.29205515
32Abnormality of the umbilical cord (HP:0010881)2.16112367
33Hyperacusis (HP:0010780)2.15914129
34Bowel diverticulosis (HP:0005222)2.15420917
35Osteolytic defects of the phalanges of the hand (HP:0009771)2.13986425
36Osteolytic defects of the hand bones (HP:0009699)2.13986425
37Broad face (HP:0000283)2.12884334
38Abnormality of carpal bone ossification (HP:0006257)2.12575309
39Abnormal gallbladder physiology (HP:0012438)2.10618657
40Cholecystitis (HP:0001082)2.10618657
41Mitral valve prolapse (HP:0001634)2.10434093
42Abnormality of the acetabulum (HP:0003170)2.10113992
43Bladder diverticulum (HP:0000015)2.09341587
44Difficulty climbing stairs (HP:0003551)2.07166632
45Abnormal ossification of hand bones (HP:0005921)2.05690880
46Termporal pattern (HP:0011008)2.05301901
47Insidious onset (HP:0003587)2.05301901
48Achilles tendon contracture (HP:0001771)2.03275008
49Atrophic scars (HP:0001075)2.03031462
50Abnormality of the distal phalanges of the toes (HP:0010182)2.02943742
51Radial bowing (HP:0002986)2.02828966
52Natal tooth (HP:0000695)2.02005890
53Angiofibromas (HP:0010615)2.01329549
54Adenoma sebaceum (HP:0009720)2.01329549
55Increased connective tissue (HP:0009025)2.01195050
56Abnormality of dentin (HP:0010299)2.00169642
57Arterial tortuosity (HP:0005116)1.99269889
58Vascular tortuosity (HP:0004948)1.98058807
59Long palpebral fissure (HP:0000637)1.97064941
60Thin bony cortex (HP:0002753)1.96845444
61Blue sclerae (HP:0000592)1.94854426
62Colon cancer (HP:0003003)1.94547178
63Progressive muscle weakness (HP:0003323)1.93912331
64Spastic diplegia (HP:0001264)1.93568336
65Rectal prolapse (HP:0002035)1.93238086
66Back pain (HP:0003418)1.93057487
67Soft skin (HP:0000977)1.92808452
68Aortic aneurysm (HP:0004942)1.92300087
69Aneurysm (HP:0002617)1.91165265
70Distal lower limb muscle weakness (HP:0009053)1.90838687
71Mildly elevated creatine phosphokinase (HP:0008180)1.90597404
72Missing ribs (HP:0000921)1.90528421
73Mitral regurgitation (HP:0001653)1.90528343
74Short humerus (HP:0005792)1.90315070
75Spinal cord lesions (HP:0100561)1.90313103
76Syringomyelia (HP:0003396)1.90313103
77Single umbilical artery (HP:0001195)1.90207206
78Abnormality of the fetal cardiovascular system (HP:0010948)1.90207206
79Abnormal umbilical cord blood vessels (HP:0011403)1.90207206
80High pitched voice (HP:0001620)1.89768854
81Aplasia/hypoplasia of the humerus (HP:0006507)1.89600923
82Slender long bone (HP:0003100)1.88761710
83Generalized amyotrophy (HP:0003700)1.88528528
84Deep venous thrombosis (HP:0002625)1.88167052
85Wormian bones (HP:0002645)1.87615505
86Short 4th metacarpal (HP:0010044)1.87338867
87Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.87338867
88Patellar dislocation (HP:0002999)1.86467467
89Orthostatic hypotension (HP:0001278)1.85643897
90Subacute progressive viral hepatitis (HP:0006572)1.85313697
91Sparse lateral eyebrow (HP:0005338)1.84762953
92Lower limb amyotrophy (HP:0007210)1.84320786
93Astrocytoma (HP:0009592)1.84005192
94Abnormality of the astrocytes (HP:0100707)1.84005192
95Abnormality of the Achilles tendon (HP:0005109)1.83209091
96Abnormality of the distal phalanx of the thumb (HP:0009617)1.83144793
97Flat acetabular roof (HP:0003180)1.82576643
98Increased nuchal translucency (HP:0010880)1.82319377
99Hallux valgus (HP:0001822)1.81987070
100Advanced eruption of teeth (HP:0006288)1.80990217
101Vertebral compression fractures (HP:0002953)1.80921537
102Abnormality of the peritoneum (HP:0002585)1.80904366
103Renal duplication (HP:0000075)1.80630702
104Metaphyseal cupping (HP:0003021)1.80545682
105Deviation of the hallux (HP:0010051)1.80081079
106Aortic dissection (HP:0002647)1.78802526
107Nonimmune hydrops fetalis (HP:0001790)1.76823930
108Abnormal delivery (HP:0001787)1.75949871
109Entropion (HP:0000621)1.75472526
110Breast hypoplasia (HP:0003187)1.75423878
111Spinal cord compression (HP:0002176)1.75171497
112Bowed forearm bones (HP:0003956)1.75001838
113Bowing of the arm (HP:0006488)1.75001838
114Gastrointestinal carcinoma (HP:0002672)1.74945218
115Malignant gastrointestinal tract tumors (HP:0006749)1.74945218
116Centrally nucleated skeletal muscle fibers (HP:0003687)1.74154369
117Relative macrocephaly (HP:0004482)1.73859747
118Cutaneous melanoma (HP:0012056)1.72384521
119Pelvic girdle muscle weakness (HP:0003749)1.71612137
120Short nail (HP:0001799)1.71579157
121Abnormal cartilage morphology (HP:0002763)1.71353499
122Wrist flexion contracture (HP:0001239)1.70623344
123Reduced subcutaneous adipose tissue (HP:0003758)1.70605920
124Thrombocytosis (HP:0001894)1.70438653
125Hyperparathyroidism (HP:0000843)1.70242278
126Premature skin wrinkling (HP:0100678)1.69638392
127Rough bone trabeculation (HP:0100670)1.68830824
128Fibroma (HP:0010614)1.68822543
129Biconcave vertebral bodies (HP:0004586)1.68399944
130Vertebral clefting (HP:0008428)1.68318269
131Biliary tract neoplasm (HP:0100574)1.67756248
132Delayed cranial suture closure (HP:0000270)1.67592070
133Elfin facies (HP:0004428)1.66972704
134Birth length less than 3rd percentile (HP:0003561)1.66406900
135Neoplasm of the pancreas (HP:0002894)1.66001058
136Fragile skin (HP:0001030)1.63514706
137Joint laxity (HP:0001388)1.63091707
138Atrophy/Degeneration involving motor neurons (HP:0007373)1.63004068
139Myocardial infarction (HP:0001658)1.62132403
140Fused cervical vertebrae (HP:0002949)1.61964238
141Fibrous tissue neoplasm (HP:0012316)1.61758890
142Overriding aorta (HP:0002623)1.60595707
143Basal cell carcinoma (HP:0002671)1.60533551
144Glossoptosis (HP:0000162)1.60320545
145Squamous cell carcinoma (HP:0002860)1.59935442
146Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.59738926
147Vertebral hypoplasia (HP:0008417)1.59738926
148Abnormality of subcutaneous fat tissue (HP:0001001)1.59530835
149Cortical dysplasia (HP:0002539)1.59354954
150Abnormalities of placenta or umbilical cord (HP:0001194)1.59079091
151Abnormality of the tricuspid valve (HP:0001702)1.59007255
152Hyperextensible skin (HP:0000974)1.58856743
153Broad thumb (HP:0011304)1.58648280
154Spinal muscular atrophy (HP:0007269)1.58631626
155Abnormal foot bone ossification (HP:0010675)1.58404541
156Breech presentation (HP:0001623)1.58340879
157Abnormality of the proximal phalanges of the hand (HP:0009834)1.56973486
158Reticulocytosis (HP:0001923)1.56036987

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.87161598
2IRAK33.34757071
3PKN23.20401668
4EEF2K3.00958030
5SMG12.96520972
6EPHA22.69508749
7MST1R2.64381159
8WEE12.41348562
9MAP3K102.40365920
10CDC72.33131784
11ERN12.18124251
12NEK22.13435124
13SCYL22.13154630
14BUB12.07003884
15PRPF4B2.01075161
16NEK11.91507516
17CDK121.91012407
18LATS21.80418148
19RPS6KB21.77633953
20RPS6KA41.74129663
21TESK21.71331389
22STK101.69858057
23PAK41.66832318
24PBK1.66621663
25MAP3K81.60491275
26LATS11.59323610
27TESK11.58695755
28NME21.56155629
29LRRK21.55978547
30TTN1.55834402
31PDGFRA1.55691828
32STK31.54820020
33DDR21.54714909
34TTK1.53418562
35PTK61.51400350
36RIPK11.49975184
37BRSK21.46360342
38FLT31.37228881
39CDK41.35814505
40PIM21.35072929
41EIF2AK11.22010341
42PAK21.21237461
43ALK1.21192425
44FGFR41.18558485
45PASK1.17981717
46MTOR1.16776467
47KSR21.14282424
48CDK61.13282737
49ERBB41.12203927
50BMX1.11423767
51CDK71.09289656
52MAP2K31.07776211
53NTRK11.06714980
54TGFBR11.06117982
55PLK11.04295387
56MAP3K111.04008346
57ARAF1.01238669
58LMTK21.00586043
59CDK80.99391864
60AURKB0.98615674
61TSSK60.96036691
62SIK10.90328369
63PAK10.87959874
64ICK0.85774961
65PTK20.84315543
66MAPKAPK30.82793994
67MAP3K30.82331581
68BRAF0.80774700
69TAOK10.80255764
70CHEK10.79799411
71ATR0.78956999
72MET0.76790029
73PLK30.73933471
74CLK10.73528143
75DYRK30.73052958
76ILK0.72088832
77EIF2AK30.71349922
78MAP3K50.70469915
79PIM10.70016177
80MOS0.69218315
81ACVR1B0.68872096
82AURKA0.68822787
83BRSK10.68210328
84CHEK20.64945774
85FGFR10.63840982
86MAP2K20.63744603
87KDR0.61515233
88LIMK10.59457848
89MAPK110.59193343
90CDK20.56101327
91MAP3K90.55664199
92EPHB10.55321177
93NEK90.52492760
94MAP3K140.51039928
95DMPK0.50769122
96ZAP700.50246706
97RAF10.47795337
98PRKCI0.47257749
99AKT20.45493366
100MAP3K130.45212651
101PDPK10.44945511
102MAP3K10.44544565
103CDK90.42750199
104IRAK20.42008654
105KSR10.40883406
106ABL20.40713424
107ATM0.40390900
108CDC42BPA0.40333452
109STK40.39704897
110CDK150.39032714
111CDK11A0.38625048
112MELK0.38597277
113MAP3K20.37858802
114JAK30.37810803
115MAP3K60.37136079
116CDK180.36547116
117PDGFRB0.36321407
118EPHB20.36185519
119MAP2K10.35336789
120RPS6KA20.34747179
121FER0.34162557
122GSK3A0.33737860
123BRD40.33711573
124SRPK10.33506533
125MAPKAPK20.33372937
126GRK60.33074899
127PLK40.31599570
128TAOK20.31336115
129PRKG20.31321086
130MATK0.30523749
131PDK30.30448085
132PDK40.30448085
133RPS6KA10.30373773
134CSNK1E0.29736943
135CDK10.28005714
136RET0.27958200

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.26527045
2One carbon pool by folate_Homo sapiens_hsa006702.85515824
3RNA transport_Homo sapiens_hsa030132.71353354
4Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.62239074
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.41907159
6Mismatch repair_Homo sapiens_hsa034302.28556281
7Cell cycle_Homo sapiens_hsa041102.27700076
8Spliceosome_Homo sapiens_hsa030402.03401337
9Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.84429462
10Base excision repair_Homo sapiens_hsa034101.80342815
11p53 signaling pathway_Homo sapiens_hsa041151.68999003
12Proteasome_Homo sapiens_hsa030501.62849861
13Other glycan degradation_Homo sapiens_hsa005111.58368129
14Bladder cancer_Homo sapiens_hsa052191.51928748
15Small cell lung cancer_Homo sapiens_hsa052221.49933056
16Nucleotide excision repair_Homo sapiens_hsa034201.43599157
17Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.42487406
18Chronic myeloid leukemia_Homo sapiens_hsa052201.42487006
19Prion diseases_Homo sapiens_hsa050201.42278286
20Selenocompound metabolism_Homo sapiens_hsa004501.40108854
21Viral carcinogenesis_Homo sapiens_hsa052031.39527846
22Biosynthesis of amino acids_Homo sapiens_hsa012301.39292872
23Ribosome_Homo sapiens_hsa030101.31393345
24mRNA surveillance pathway_Homo sapiens_hsa030151.28736264
25Thyroid cancer_Homo sapiens_hsa052161.27237859
26MicroRNAs in cancer_Homo sapiens_hsa052061.26017432
27Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.24148287
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23431048
29Pentose phosphate pathway_Homo sapiens_hsa000301.22925079
30Hippo signaling pathway_Homo sapiens_hsa043901.21751643
31Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.20494079
32Adherens junction_Homo sapiens_hsa045201.18978138
33Legionellosis_Homo sapiens_hsa051341.15414970
34Central carbon metabolism in cancer_Homo sapiens_hsa052301.13233629
35Proteoglycans in cancer_Homo sapiens_hsa052051.11616900
36N-Glycan biosynthesis_Homo sapiens_hsa005101.11343978
37Pyrimidine metabolism_Homo sapiens_hsa002401.10252425
38Vibrio cholerae infection_Homo sapiens_hsa051101.09098028
39Antigen processing and presentation_Homo sapiens_hsa046121.07451578
40Renal cell carcinoma_Homo sapiens_hsa052111.07279897
41Vitamin B6 metabolism_Homo sapiens_hsa007501.06813073
42mTOR signaling pathway_Homo sapiens_hsa041501.04559905
43Homologous recombination_Homo sapiens_hsa034401.03673409
44Apoptosis_Homo sapiens_hsa042101.03222188
45Shigellosis_Homo sapiens_hsa051311.02008410
46Fat digestion and absorption_Homo sapiens_hsa049751.01287539
47Epstein-Barr virus infection_Homo sapiens_hsa051691.00436656
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98954385
49HTLV-I infection_Homo sapiens_hsa051660.98023028
50Focal adhesion_Homo sapiens_hsa045100.97919279
51RNA polymerase_Homo sapiens_hsa030200.97349977
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96697624
53Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.96354087
54Renin-angiotensin system_Homo sapiens_hsa046140.92713078
55ECM-receptor interaction_Homo sapiens_hsa045120.91829260
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90850507
57Carbon metabolism_Homo sapiens_hsa012000.90800330
58Folate biosynthesis_Homo sapiens_hsa007900.88762177
59ErbB signaling pathway_Homo sapiens_hsa040120.88361556
60TGF-beta signaling pathway_Homo sapiens_hsa043500.87313452
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.85934824
62Colorectal cancer_Homo sapiens_hsa052100.84718863
63Cysteine and methionine metabolism_Homo sapiens_hsa002700.83613771
64Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.82509280
65Pancreatic cancer_Homo sapiens_hsa052120.81963918
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.81782907
67Galactose metabolism_Homo sapiens_hsa000520.81770915
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.80875835
69Acute myeloid leukemia_Homo sapiens_hsa052210.80463038
70Sulfur relay system_Homo sapiens_hsa041220.80400447
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80399125
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.79470903
73Insulin signaling pathway_Homo sapiens_hsa049100.78721670
74AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.77426200
75Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.76209701
76Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.75631950
77Viral myocarditis_Homo sapiens_hsa054160.74489153
78Protein digestion and absorption_Homo sapiens_hsa049740.73312912
79Hepatitis B_Homo sapiens_hsa051610.72379641
80Arginine biosynthesis_Homo sapiens_hsa002200.70699139
81Drug metabolism - other enzymes_Homo sapiens_hsa009830.70073317
82Endometrial cancer_Homo sapiens_hsa052130.70052415
83Amoebiasis_Homo sapiens_hsa051460.69749059
84Non-homologous end-joining_Homo sapiens_hsa034500.68265790
85Systemic lupus erythematosus_Homo sapiens_hsa053220.67278517
86Leukocyte transendothelial migration_Homo sapiens_hsa046700.66745007
87Fructose and mannose metabolism_Homo sapiens_hsa000510.66384659
88RNA degradation_Homo sapiens_hsa030180.66170642
89HIF-1 signaling pathway_Homo sapiens_hsa040660.66149878
90Oocyte meiosis_Homo sapiens_hsa041140.65928157
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65529615
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.64890141
93Melanoma_Homo sapiens_hsa052180.64730867
94Salmonella infection_Homo sapiens_hsa051320.63398930
95Herpes simplex infection_Homo sapiens_hsa051680.63105188
96Prostate cancer_Homo sapiens_hsa052150.62654089
97Basal cell carcinoma_Homo sapiens_hsa052170.61648675
98Non-small cell lung cancer_Homo sapiens_hsa052230.61086908
99Hepatitis C_Homo sapiens_hsa051600.59718096
100Toxoplasmosis_Homo sapiens_hsa051450.59415711
101Tight junction_Homo sapiens_hsa045300.57995035
102Notch signaling pathway_Homo sapiens_hsa043300.57150771
103Pyruvate metabolism_Homo sapiens_hsa006200.56428021
104VEGF signaling pathway_Homo sapiens_hsa043700.53824181
105AMPK signaling pathway_Homo sapiens_hsa041520.52328695
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52288838
107Endocytosis_Homo sapiens_hsa041440.50444334
108PI3K-Akt signaling pathway_Homo sapiens_hsa041510.49761525
109Pathways in cancer_Homo sapiens_hsa052000.48848757
110Fanconi anemia pathway_Homo sapiens_hsa034600.47460312
111Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.46922649
112TNF signaling pathway_Homo sapiens_hsa046680.46583754
113Estrogen signaling pathway_Homo sapiens_hsa049150.46497103
114Lysine degradation_Homo sapiens_hsa003100.46410651
115Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45956403
116Glutathione metabolism_Homo sapiens_hsa004800.45357896
117Sulfur metabolism_Homo sapiens_hsa009200.44889769
118Prolactin signaling pathway_Homo sapiens_hsa049170.44081590
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43224834
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42489452
121Glioma_Homo sapiens_hsa052140.41383460
122Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40799416
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.40024627
124Sphingolipid metabolism_Homo sapiens_hsa006000.39890539
125Caffeine metabolism_Homo sapiens_hsa002320.39325359

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