LRRC4C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)6.62928526
2synaptic vesicle docking involved in exocytosis (GO:0016081)6.43568820
3presynaptic membrane organization (GO:0097090)6.10544554
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act6.10185608
5pyrimidine nucleobase catabolic process (GO:0006208)6.01567089
6neurotransmitter-gated ion channel clustering (GO:0072578)6.00337334
7neuron cell-cell adhesion (GO:0007158)5.99310676
8vocalization behavior (GO:0071625)5.89439953
9regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)5.63843060
10postsynaptic membrane organization (GO:0001941)5.60788936
11synaptic vesicle exocytosis (GO:0016079)5.56539864
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.52648935
13glutamate secretion (GO:0014047)5.52177228
14protein localization to synapse (GO:0035418)5.35713751
15regulation of synaptic vesicle exocytosis (GO:2000300)5.17082015
16regulation of short-term neuronal synaptic plasticity (GO:0048172)5.16908372
17regulation of glutamate receptor signaling pathway (GO:1900449)5.13558548
18cerebellar granule cell differentiation (GO:0021707)4.84989505
19nucleobase catabolic process (GO:0046113)4.80101936
20negative regulation of synaptic transmission, GABAergic (GO:0032229)4.73390113
21gamma-aminobutyric acid signaling pathway (GO:0007214)4.64682562
22neuron-neuron synaptic transmission (GO:0007270)4.48106702
23response to histamine (GO:0034776)4.45383281
24regulation of synaptic vesicle transport (GO:1902803)4.42579679
25ionotropic glutamate receptor signaling pathway (GO:0035235)4.40353959
26positive regulation of synapse maturation (GO:0090129)4.36461738
27neuronal action potential propagation (GO:0019227)4.35565618
28synaptic transmission, glutamatergic (GO:0035249)4.35494050
29locomotory exploration behavior (GO:0035641)4.32551915
30behavioral response to nicotine (GO:0035095)4.29605506
31glutamate receptor signaling pathway (GO:0007215)4.26649583
32long-term synaptic potentiation (GO:0060291)4.24658268
33neurotransmitter secretion (GO:0007269)4.17849197
34mechanosensory behavior (GO:0007638)4.17385202
35positive regulation of neurotransmitter secretion (GO:0001956)4.14308654
36regulation of excitatory postsynaptic membrane potential (GO:0060079)4.08798087
37startle response (GO:0001964)4.01366295
38regulation of synaptic transmission, glutamatergic (GO:0051966)3.97631355
39dendritic spine morphogenesis (GO:0060997)3.95051415
40regulation of postsynaptic membrane potential (GO:0060078)3.94061146
41synaptic vesicle maturation (GO:0016188)3.93392559
42regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.91704518
43positive regulation of synapse assembly (GO:0051965)3.83184397
44auditory behavior (GO:0031223)3.81826607
45positive regulation of membrane potential (GO:0045838)3.79798369
46positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.79011894
47G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.76539322
48regulation of synapse maturation (GO:0090128)3.69978747
49membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.66951886
50positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.66357330
51retinal ganglion cell axon guidance (GO:0031290)3.65578634
52negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.64372737
53regulation of neurotransmitter secretion (GO:0046928)3.62763536
54positive regulation of neurotransmitter transport (GO:0051590)3.62093776
55neurofilament cytoskeleton organization (GO:0060052)3.62059187
56central nervous system myelination (GO:0022010)3.54536965
57axon ensheathment in central nervous system (GO:0032291)3.54536965
58regulation of long-term neuronal synaptic plasticity (GO:0048169)3.53349167
59regulation of synaptic plasticity (GO:0048167)3.51820917
60limb bud formation (GO:0060174)3.49912495
61exploration behavior (GO:0035640)3.48725418
62regulation of glutamate secretion (GO:0014048)3.48408854
63regulation of neuronal synaptic plasticity (GO:0048168)3.46862130
64behavioral response to cocaine (GO:0048148)3.45167483
65neuron recognition (GO:0008038)3.41107843
66transferrin transport (GO:0033572)3.39795958
67neurotransmitter transport (GO:0006836)3.39213578
68positive regulation of synaptic transmission (GO:0050806)3.31538410
69nonmotile primary cilium assembly (GO:0035058)3.30008199
70energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.28907213
71ATP hydrolysis coupled proton transport (GO:0015991)3.28907213
72female mating behavior (GO:0060180)3.28771915
73regulation of female receptivity (GO:0045924)3.28493138
74regulation of voltage-gated calcium channel activity (GO:1901385)3.27719834
75central nervous system projection neuron axonogenesis (GO:0021952)3.27332801
76regulation of neurotransmitter transport (GO:0051588)3.25845037
77regulation of synapse assembly (GO:0051963)3.25466589
78synaptic vesicle endocytosis (GO:0048488)3.23228995
79gamma-aminobutyric acid transport (GO:0015812)3.20715059
80regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.17986351
81negative regulation of dendrite morphogenesis (GO:0050774)3.17643738
82membrane depolarization (GO:0051899)3.17490151
83ferric iron transport (GO:0015682)3.16521477
84trivalent inorganic cation transport (GO:0072512)3.16521477
85membrane assembly (GO:0071709)3.16229111
86long-term memory (GO:0007616)3.15985381
87cerebellar Purkinje cell differentiation (GO:0021702)3.15548747
88synapse assembly (GO:0007416)3.14388398
89cell proliferation in forebrain (GO:0021846)3.12983513
90serotonin metabolic process (GO:0042428)3.11266075
91response to auditory stimulus (GO:0010996)3.10813426
92regulation of neurotransmitter levels (GO:0001505)3.10397896
93behavioral fear response (GO:0001662)3.10350014
94behavioral defense response (GO:0002209)3.10350014
95spinal cord development (GO:0021510)3.08761894
96learning (GO:0007612)3.05971517
97neurotransmitter uptake (GO:0001504)3.05469737
98positive regulation of synaptic transmission, GABAergic (GO:0032230)3.05426072
99membrane hyperpolarization (GO:0060081)3.05295874
100transmission of nerve impulse (GO:0019226)3.03935993
101establishment of mitochondrion localization (GO:0051654)3.02567584
102fear response (GO:0042596)3.02106497
103cell migration in hindbrain (GO:0021535)3.00961365
104regulation of synaptic transmission (GO:0050804)3.00894143
105regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.00349416
106synaptic transmission (GO:0007268)2.99236175
107negative regulation of neurotransmitter transport (GO:0051589)2.99028100
108otic vesicle formation (GO:0030916)2.95981327
109negative regulation of oligodendrocyte differentiation (GO:0048715)2.95648379
110regulation of dendritic spine development (GO:0060998)2.95625258
111regulation of synapse structural plasticity (GO:0051823)2.95438524
112negative regulation of axon extension (GO:0030517)2.95434202
113axonal fasciculation (GO:0007413)2.94371313
114neuronal action potential (GO:0019228)2.93508962
115negative regulation of amino acid transport (GO:0051956)2.93118604
116regulation of synaptic transmission, GABAergic (GO:0032228)2.93013614
117neuromuscular synaptic transmission (GO:0007274)2.92885575
118dendrite morphogenesis (GO:0048813)2.92761313
119regulation of vesicle fusion (GO:0031338)2.92410862
120regulation of dendritic spine morphogenesis (GO:0061001)2.92099672
121negative regulation of dendrite development (GO:2000171)2.91471817
122somite development (GO:0061053)2.89838222
123forebrain neuron differentiation (GO:0021879)2.88217353
124protein polyglutamylation (GO:0018095)2.87978351
125positive regulation of potassium ion transmembrane transport (GO:1901381)2.83515143
126membrane depolarization during action potential (GO:0086010)2.82061755
127adult walking behavior (GO:0007628)2.79462539
128negative regulation of glial cell differentiation (GO:0045686)2.79209696
129C4-dicarboxylate transport (GO:0015740)2.74697458
130positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.74251475
131positive regulation of amino acid transport (GO:0051957)2.74104432
132cochlea development (GO:0090102)2.74058938
133neuronal stem cell maintenance (GO:0097150)2.73065905
134synapse organization (GO:0050808)2.71178392
135regulation of collateral sprouting (GO:0048670)2.67159429
136positive regulation of action potential (GO:0045760)2.67133407
137negative regulation of astrocyte differentiation (GO:0048712)2.66747852
138regulation of action potential (GO:0098900)2.66641840
139tachykinin receptor signaling pathway (GO:0007217)2.66085595
140central nervous system neuron axonogenesis (GO:0021955)2.59733423
141calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.59692847
142prepulse inhibition (GO:0060134)2.58856719
143negative regulation of axon guidance (GO:1902668)2.58498484
144positive regulation of oligodendrocyte differentiation (GO:0048714)2.56389952
145detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.55845553
146epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.55772377
147negative regulation of transcription regulatory region DNA binding (GO:2000678)2.52430667
148establishment of protein localization to mitochondrial membrane (GO:0090151)2.52287109
149establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.51333253
150mitochondrion transport along microtubule (GO:0047497)2.51333253
151negative regulation of axonogenesis (GO:0050771)2.49735674
152epithelial cilium movement (GO:0003351)2.49469055
153cerebral cortex radially oriented cell migration (GO:0021799)2.49382617
154adult behavior (GO:0030534)2.49245416
155regulation of synapse organization (GO:0050807)2.48083039

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.97347708
2EZH2_22144423_ChIP-Seq_EOC_Human4.93723354
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.11073776
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.09249958
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98432679
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.92056269
7TAF15_26573619_Chip-Seq_HEK293_Human2.89776536
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57655830
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.49757183
10* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.47413166
11* REST_21632747_ChIP-Seq_MESCs_Mouse2.44658305
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.44080631
13* EZH2_27304074_Chip-Seq_ESCs_Mouse2.43666717
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.41660811
15EZH2_18974828_ChIP-Seq_MESCs_Mouse2.41660811
16JARID2_20075857_ChIP-Seq_MESCs_Mouse2.36171126
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.35704556
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.35523284
19* ZFP57_27257070_Chip-Seq_ESCs_Mouse2.29584797
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22015722
21* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21575579
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.20849430
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.18929009
24* CTBP1_25329375_ChIP-Seq_LNCAP_Human2.16646529
25* RARB_27405468_Chip-Seq_BRAIN_Mouse2.10064524
26* REST_18959480_ChIP-ChIP_MESCs_Mouse1.98207130
27* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.96621856
28RNF2_27304074_Chip-Seq_ESCs_Mouse1.94864304
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94800763
30* P300_19829295_ChIP-Seq_ESCs_Human1.93082375
31* SMAD4_21799915_ChIP-Seq_A2780_Human1.90870764
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.90816412
33AR_21572438_ChIP-Seq_LNCaP_Human1.90143949
34* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.87961380
35FUS_26573619_Chip-Seq_HEK293_Human1.87435546
36POU3F2_20337985_ChIP-ChIP_501MEL_Human1.87391063
37DROSHA_22980978_ChIP-Seq_HELA_Human1.85683728
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84930728
39VDR_22108803_ChIP-Seq_LS180_Human1.75871979
40SMAD_19615063_ChIP-ChIP_OVARY_Human1.74229836
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.69435589
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.63949962
43* CBX2_27304074_Chip-Seq_ESCs_Mouse1.63803426
44* SMAD3_21741376_ChIP-Seq_EPCs_Human1.63691465
45* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60575789
46IKZF1_21737484_ChIP-ChIP_HCT116_Human1.59377266
47* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57336181
48CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.54771897
49* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51099902
50* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.50570001
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47527130
52* AR_25329375_ChIP-Seq_VCAP_Human1.43257907
53RBPJ_22232070_ChIP-Seq_NCS_Mouse1.42560618
54PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.41295516
55* RNF2_27304074_Chip-Seq_NSC_Mouse1.39672864
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.38188111
57* SOX2_21211035_ChIP-Seq_LN229_Gbm1.36848463
58* ER_23166858_ChIP-Seq_MCF-7_Human1.36502828
59SALL1_21062744_ChIP-ChIP_HESCs_Human1.35811985
60STAT3_23295773_ChIP-Seq_U87_Human1.34428039
61TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.30760118
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.27694458
63* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.27032101
64* TCF4_23295773_ChIP-Seq_U87_Human1.26665507
65NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26099954
66* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.24887383
67NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23737420
68* ARNT_22903824_ChIP-Seq_MCF-7_Human1.21966029
69P53_22127205_ChIP-Seq_FIBROBLAST_Human1.21365718
70RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20961969
71* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19416947
72* NANOG_18555785_Chip-Seq_ESCs_Mouse1.19407184
73MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.19400509
74* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.16574779
75* PRDM14_20953172_ChIP-Seq_ESCs_Human1.12552264
76IGF1R_20145208_ChIP-Seq_DFB_Human1.11984269
77MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11331949
78JUN_21703547_ChIP-Seq_K562_Human1.10205067
79* AHR_22903824_ChIP-Seq_MCF-7_Human1.09033836
80TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.08966075
81* SOX9_26525672_Chip-Seq_HEART_Mouse1.08864850
82* RUNX2_22187159_ChIP-Seq_PCA_Human1.08639019
83* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08248208
84VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.07329322
85POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07109322
86TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07109322
87AR_19668381_ChIP-Seq_PC3_Human1.07021479
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06542124
89PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05997794
90STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05459085
91* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05242969
92ZNF274_21170338_ChIP-Seq_K562_Hela1.04202406
93IRF1_19129219_ChIP-ChIP_H3396_Human1.04145801
94* E2F1_18555785_Chip-Seq_ESCs_Mouse1.03849398
95* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.03108793
96* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01646984
97TP53_18474530_ChIP-ChIP_U2OS_Human1.01605059
98TP53_20018659_ChIP-ChIP_R1E_Mouse1.01100660
99* P53_22387025_ChIP-Seq_ESCs_Mouse1.01097905
100* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00921795
101FLI1_27457419_Chip-Seq_LIVER_Mouse1.00860475
102* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00454682
103RING1B_27294783_Chip-Seq_ESCs_Mouse1.00367869
104CMYC_18555785_Chip-Seq_ESCs_Mouse1.00033130
105* KDM2B_26808549_Chip-Seq_REH_Human1.00006555
106BCAT_22108803_ChIP-Seq_LS180_Human0.99450572
107EWS_26573619_Chip-Seq_HEK293_Human0.98714669
108MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98230249
109MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.97694703
110ERG_21242973_ChIP-ChIP_JURKAT_Human0.97663295
111* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97241974
112CBP_20019798_ChIP-Seq_JUKART_Human0.97074287
113IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97074287
114* TAL1_26923725_Chip-Seq_HPCs_Mouse0.96822631
115RING1B_27294783_Chip-Seq_NPCs_Mouse0.96151653
116TBX3_20139965_ChIP-Seq_MESCs_Mouse0.95229352
117CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94974642
118FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94751018
119RXR_22108803_ChIP-Seq_LS180_Human0.92367817
120PCGF2_27294783_Chip-Seq_ESCs_Mouse0.91354951

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern6.15036405
2MP0004859_abnormal_synaptic_plasticity5.10045344
3MP0003635_abnormal_synaptic_transmissio3.91837405
4MP0009745_abnormal_behavioral_response3.62124885
5MP0001968_abnormal_touch/_nociception3.48911801
6MP0004270_analgesia3.45705388
7MP0009046_muscle_twitch3.34896638
8MP0002064_seizures3.32776784
9MP0002063_abnormal_learning/memory/cond3.27907948
10MP0003136_yellow_coat_color3.11432315
11MP0002736_abnormal_nociception_after3.03395490
12MP0002572_abnormal_emotion/affect_behav2.95979482
13MP0009780_abnormal_chondrocyte_physiolo2.75116441
14MP0002272_abnormal_nervous_system2.69559106
15MP0001486_abnormal_startle_reflex2.52289443
16MP0002734_abnormal_mechanical_nocicepti2.50851722
17MP0005646_abnormal_pituitary_gland2.40341293
18MP0002067_abnormal_sensory_capabilities2.28138323
19MP0001501_abnormal_sleep_pattern2.26934691
20MP0002735_abnormal_chemical_nociception2.26627398
21MP0001440_abnormal_grooming_behavior2.20968836
22MP0003879_abnormal_hair_cell2.20432912
23MP0002822_catalepsy2.18070487
24MP0005423_abnormal_somatic_nervous1.92587514
25MP0003787_abnormal_imprinting1.90964338
26MP0001188_hyperpigmentation1.90499663
27MP0002638_abnormal_pupillary_reflex1.84276071
28MP0001984_abnormal_olfaction1.81625675
29MP0001529_abnormal_vocalization1.79263684
30MP0001970_abnormal_pain_threshold1.76495407
31MP0000569_abnormal_digit_pigmentation1.76127341
32MP0000778_abnormal_nervous_system1.74023760
33MP0005386_behavior/neurological_phenoty1.71596142
34MP0004924_abnormal_behavior1.71596142
35MP0002557_abnormal_social/conspecific_i1.71401204
36MP0002733_abnormal_thermal_nociception1.69294461
37MP0002184_abnormal_innervation1.62923160
38MP0004133_heterotaxia1.61862638
39MP0008569_lethality_at_weaning1.60353487
40MP0002876_abnormal_thyroid_physiology1.59288353
41MP0006276_abnormal_autonomic_nervous1.57925663
42MP0004142_abnormal_muscle_tone1.48772384
43MP0002837_dystrophic_cardiac_calcinosis1.45667483
44MP0006292_abnormal_olfactory_placode1.45484674
45MP0001502_abnormal_circadian_rhythm1.43792303
46MP0004811_abnormal_neuron_physiology1.41992782
47MP0003329_amyloid_beta_deposits1.41900160
48MP0001905_abnormal_dopamine_level1.41431213
49MP0002066_abnormal_motor_capabilities/c1.36224984
50MP0005171_absent_coat_pigmentation1.35054243
51MP0006072_abnormal_retinal_apoptosis1.34940582
52MP0004742_abnormal_vestibular_system1.33603661
53MP0003122_maternal_imprinting1.33516628
54MP0009379_abnormal_foot_pigmentation1.32792926
55MP0002882_abnormal_neuron_morphology1.31184342
56MP0003633_abnormal_nervous_system1.28762832
57MP0000955_abnormal_spinal_cord1.26854065
58MP0002751_abnormal_autonomic_nervous1.26479208
59MP0005551_abnormal_eye_electrophysiolog1.25213035
60MP0005645_abnormal_hypothalamus_physiol1.22256103
61MP0001986_abnormal_taste_sensitivity1.21288919
62MP0000566_synostosis1.21005550
63MP0002928_abnormal_bile_duct1.18103647
64MP0003890_abnormal_embryonic-extraembry1.13611764
65MP0001963_abnormal_hearing_physiology1.11123548
66MP0003011_delayed_dark_adaptation1.09716274
67MP0003631_nervous_system_phenotype1.09388099
68MP0000049_abnormal_middle_ear1.06587638
69MP0002102_abnormal_ear_morphology1.06064147
70MP0002938_white_spotting1.04488963
71MP0004885_abnormal_endolymph1.02444218
72MP0003861_abnormal_nervous_system1.01866274
73MP0005187_abnormal_penis_morphology0.99825698
74MP0005195_abnormal_posterior_eye0.99191996
75MP0008004_abnormal_stomach_pH0.98947731
76MP0002229_neurodegeneration0.98189607
77MP0002152_abnormal_brain_morphology0.97670137
78MP0003283_abnormal_digestive_organ0.96818448
79MP0000751_myopathy0.96531239
80MP0003183_abnormal_peptide_metabolism0.96089965
81MP0008872_abnormal_physiological_respon0.94227803
82MP0002909_abnormal_adrenal_gland0.93390655
83MP0000631_abnormal_neuroendocrine_gland0.91341945
84MP0003938_abnormal_ear_development0.90758061
85MP0004145_abnormal_muscle_electrophysio0.89696412
86MP0010386_abnormal_urinary_bladder0.88420719
87MP0002069_abnormal_eating/drinking_beha0.87821113
88MP0003119_abnormal_digestive_system0.87520931
89MP0004085_abnormal_heartbeat0.86714419
90MP0008874_decreased_physiological_sensi0.85271300
91MP0003123_paternal_imprinting0.84982281
92MP0002653_abnormal_ependyma_morphology0.84503026
93MP0001485_abnormal_pinna_reflex0.84417405
94MP0004215_abnormal_myocardial_fiber0.84203247
95MP0001664_abnormal_digestion0.82225748
96MP0000013_abnormal_adipose_tissue0.81638698
97MP0001293_anophthalmia0.80645821
98MP0003937_abnormal_limbs/digits/tail_de0.80576712
99MP0004858_abnormal_nervous_system0.79268924
100MP0005084_abnormal_gallbladder_morpholo0.77751277
101MP0008789_abnormal_olfactory_epithelium0.77675937
102MP0002752_abnormal_somatic_nervous0.77016609
103MP0003755_abnormal_palate_morphology0.76416158
104MP0000026_abnormal_inner_ear0.75693902
105MP0001299_abnormal_eye_distance/0.74889663
106MP0008877_abnormal_DNA_methylation0.74655058
107MP0009250_abnormal_appendicular_skeleto0.73145870
108MP0005409_darkened_coat_color0.71727792
109MP0005174_abnormal_tail_pigmentation0.71342607
110MP0000920_abnormal_myelination0.70940473
111MP0004134_abnormal_chest_morphology0.70478290
112MP0005535_abnormal_body_temperature0.70358157
113MP0002282_abnormal_trachea_morphology0.70308648
114MP0000534_abnormal_ureter_morphology0.69508839
115MP0004484_altered_response_of0.69410644
116MP0004043_abnormal_pH_regulation0.67960297
117MP0003632_abnormal_nervous_system0.67114205
118MP0003634_abnormal_glial_cell0.65813707
119MP0001177_atelectasis0.64020909
120MP0001943_abnormal_respiration0.63978487
121MP0003690_abnormal_glial_cell0.59597413
122MP0002090_abnormal_vision0.58787090
123MP0005394_taste/olfaction_phenotype0.57120195
124MP0005499_abnormal_olfactory_system0.57120195
125MP0010770_preweaning_lethality0.55169340
126MP0002082_postnatal_lethality0.55169340
127MP0000604_amyloidosis0.53300836
128MP0010769_abnormal_survival0.51936934
129MP0005623_abnormal_meninges_morphology0.51416874
130MP0010768_mortality/aging0.49386316
131MP0004233_abnormal_muscle_weight0.49112598
132MP0003121_genomic_imprinting0.48460112
133MP0004036_abnormal_muscle_relaxation0.48360203
134MP0005253_abnormal_eye_physiology0.46642065

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)9.08507006
2Epileptic encephalopathy (HP:0200134)7.09170155
3Hyperventilation (HP:0002883)6.61543120
4Atonic seizures (HP:0010819)6.39762236
5Focal seizures (HP:0007359)5.63946437
6Febrile seizures (HP:0002373)5.40556936
7Absence seizures (HP:0002121)4.90056671
8Septo-optic dysplasia (HP:0100842)4.88906025
9Dialeptic seizures (HP:0011146)4.66875141
10Myokymia (HP:0002411)4.55898500
11Broad-based gait (HP:0002136)4.46811273
12Visual hallucinations (HP:0002367)3.85863172
13Generalized tonic-clonic seizures (HP:0002069)3.81159146
14Progressive cerebellar ataxia (HP:0002073)3.54065825
15Gaze-evoked nystagmus (HP:0000640)3.52916956
16True hermaphroditism (HP:0010459)3.43737290
17Optic nerve hypoplasia (HP:0000609)3.40816603
18Protruding tongue (HP:0010808)3.36844547
19Abnormality of midbrain morphology (HP:0002418)3.28219206
20Molar tooth sign on MRI (HP:0002419)3.28219206
21Poor eye contact (HP:0000817)3.23971814
22Nephronophthisis (HP:0000090)3.15931062
23Excessive salivation (HP:0003781)3.13209374
24Drooling (HP:0002307)3.13209374
25Aplasia/Hypoplasia of the optic nerve (HP:0008058)3.01945790
26Epileptiform EEG discharges (HP:0011182)2.97459703
27Pancreatic fibrosis (HP:0100732)2.92595268
28Dysdiadochokinesis (HP:0002075)2.91924129
29Inability to walk (HP:0002540)2.91922416
30Abnormal eating behavior (HP:0100738)2.91886995
31Amblyopia (HP:0000646)2.91880248
32Abnormal hair whorl (HP:0010721)2.90646007
33Hemiplegia (HP:0002301)2.86672056
34Pancreatic cysts (HP:0001737)2.85906478
35Impaired social interactions (HP:0000735)2.84981508
36Abnormal social behavior (HP:0012433)2.84981508
37Absent septum pellucidum (HP:0001331)2.82568763
38Sensory axonal neuropathy (HP:0003390)2.80966018
39Impaired vibration sensation in the lower limbs (HP:0002166)2.78724922
40Truncal ataxia (HP:0002078)2.75490864
41Gait imbalance (HP:0002141)2.71404047
42Dysmetric saccades (HP:0000641)2.68513634
43Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.66659966
44Degeneration of the lateral corticospinal tracts (HP:0002314)2.66659966
45Polyphagia (HP:0002591)2.64990565
46Hyperthyroidism (HP:0000836)2.59785448
47Abnormality of the renal medulla (HP:0100957)2.59327332
48Absent speech (HP:0001344)2.58941642
49Insidious onset (HP:0003587)2.58064206
50Termporal pattern (HP:0011008)2.58064206
51Ulnar claw (HP:0001178)2.57623794
52Megalencephaly (HP:0001355)2.56069871
53EEG with generalized epileptiform discharges (HP:0011198)2.54432569
54Blue irides (HP:0000635)2.54027751
55Urinary bladder sphincter dysfunction (HP:0002839)2.52694318
56Medial flaring of the eyebrow (HP:0010747)2.49284897
57Fetal akinesia sequence (HP:0001989)2.49016052
58Pheochromocytoma (HP:0002666)2.46887672
59Dysmetria (HP:0001310)2.45358198
60Pendular nystagmus (HP:0012043)2.44639936
61Congenital primary aphakia (HP:0007707)2.44627792
62Abnormality of the corticospinal tract (HP:0002492)2.44142458
63Scanning speech (HP:0002168)2.43252616
64Nephrogenic diabetes insipidus (HP:0009806)2.38009976
65Progressive inability to walk (HP:0002505)2.36200716
66Anxiety (HP:0000739)2.34980679
67Depression (HP:0000716)2.34341033
68Agitation (HP:0000713)2.34140823
69Poor suck (HP:0002033)2.33479659
70Impaired smooth pursuit (HP:0007772)2.33035641
71Abnormality of glycolysis (HP:0004366)2.29943724
72Increased serum pyruvate (HP:0003542)2.29943724
73Hypsarrhythmia (HP:0002521)2.29023796
74Type II lissencephaly (HP:0007260)2.28007518
75Neuroendocrine neoplasm (HP:0100634)2.26788169
76Action tremor (HP:0002345)2.26205483
77Lissencephaly (HP:0001339)2.25781239
78Abnormality of the septum pellucidum (HP:0007375)2.24714025
79Oligodactyly (hands) (HP:0001180)2.22542636
80Sclerocornea (HP:0000647)2.17610858
81Retinal dysplasia (HP:0007973)2.17422116
82Stereotypic behavior (HP:0000733)2.17346704
83Spastic gait (HP:0002064)2.16802623
84Thickened helices (HP:0000391)2.16280959
85Esophageal atresia (HP:0002032)2.15060928
86Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.14814023
87Short 4th metacarpal (HP:0010044)2.14814023
88Impaired vibratory sensation (HP:0002495)2.14230502
89Growth hormone deficiency (HP:0000824)2.13740064
90Anophthalmia (HP:0000528)2.13600545
91Ankle clonus (HP:0011448)2.13252584
92Abnormal ciliary motility (HP:0012262)2.11917577
93Abnormality of salivation (HP:0100755)2.10529595
94Chorioretinal atrophy (HP:0000533)2.10462533
95Abnormality of the labia minora (HP:0012880)2.10427855
96Specific learning disability (HP:0001328)2.08516194
97Dynein arm defect of respiratory motile cilia (HP:0012255)2.07997870
98Absent/shortened dynein arms (HP:0200106)2.07997870
99Status epilepticus (HP:0002133)2.07691489
100Generalized myoclonic seizures (HP:0002123)2.05841832
101Pachygyria (HP:0001302)2.04086726
102Abolished electroretinogram (ERG) (HP:0000550)2.03256508
103Abnormality of binocular vision (HP:0011514)2.02653368
104Diplopia (HP:0000651)2.02653368
105Hemiparesis (HP:0001269)2.02550888
106Hyperglycinemia (HP:0002154)2.01988250
107Urinary urgency (HP:0000012)2.00252949
108Thyroid-stimulating hormone excess (HP:0002925)2.00121596
109Acute necrotizing encephalopathy (HP:0006965)1.98643637
110Limb dystonia (HP:0002451)1.98470133
111Bradykinesia (HP:0002067)1.98323819
112Rib fusion (HP:0000902)1.97698655
113Cystic liver disease (HP:0006706)1.97549088
114Akinesia (HP:0002304)1.96974903
115Hepatoblastoma (HP:0002884)1.96439537
116Genetic anticipation (HP:0003743)1.96015220
117Abnormal mitochondria in muscle tissue (HP:0008316)1.95986853
118Chronic hepatic failure (HP:0100626)1.95155507
119Abnormality of the 4th metacarpal (HP:0010012)1.95032671
120Narrow nasal bridge (HP:0000446)1.94325042
121Resting tremor (HP:0002322)1.93969564
122Aplasia/Hypoplasia of the tibia (HP:0005772)1.90892196
123Congenital stationary night blindness (HP:0007642)1.90871778
124Incomplete penetrance (HP:0003829)1.90210014
125Postural instability (HP:0002172)1.89953038
126Vaginal atresia (HP:0000148)1.89226251
127Genital tract atresia (HP:0001827)1.89123834
128Abnormal respiratory motile cilium physiology (HP:0012261)1.88639094
129Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.87847558
130Abnormality of ocular smooth pursuit (HP:0000617)1.87442084
131Lower limb muscle weakness (HP:0007340)1.86711131
132Postaxial hand polydactyly (HP:0001162)1.86669174
133Abnormality of the lower motor neuron (HP:0002366)1.86243425
134Failure to thrive in infancy (HP:0001531)1.85776429
135Progressive macrocephaly (HP:0004481)1.85594054
136Abnormal respiratory motile cilium morphology (HP:0005938)1.85309506
137Abnormal respiratory epithelium morphology (HP:0012253)1.85309506
138Fair hair (HP:0002286)1.85161164
139Poor coordination (HP:0002370)1.84983530
140Gastrointestinal atresia (HP:0002589)1.84982023
141Anencephaly (HP:0002323)1.84249995
142Oligomenorrhea (HP:0000876)1.84241351
143Supranuclear gaze palsy (HP:0000605)1.83912865
144Torticollis (HP:0000473)1.82924942
145Gait ataxia (HP:0002066)1.81792391
146Gastroesophageal reflux (HP:0002020)1.81641784
147Bilateral microphthalmos (HP:0007633)1.80430016
148Morphological abnormality of the pyramidal tract (HP:0002062)1.79520428
149Aplasia/Hypoplasia of the sternum (HP:0006714)1.78504297
150Congenital, generalized hypertrichosis (HP:0004540)1.76737451
151Cutaneous finger syndactyly (HP:0010554)1.76202336
152Occipital encephalocele (HP:0002085)1.74334086
153Spastic tetraplegia (HP:0002510)1.72813778
154Maternal diabetes (HP:0009800)1.71809223
155Renal hypoplasia (HP:0000089)1.71244697
156Short tibia (HP:0005736)1.69139802
157Abnormality of the diencephalon (HP:0010662)1.66909196
158Midline defect of the nose (HP:0004122)1.66387998
159Hemivertebrae (HP:0002937)1.65968108

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK7.77295277
2EPHA43.98918813
3NTRK33.38686411
4DAPK23.08306950
5CCNB13.02574381
6CDK192.85482504
7MAP2K72.79668931
8MAP3K42.71105439
9MAPK152.60770511
10MAP3K122.42128341
11DYRK22.37713827
12AKT32.33797816
13PRPF4B2.27704948
14PLK22.27595006
15PINK12.24085738
16DAPK12.19346265
17FRK1.98220860
18OXSR11.96244890
19MAP3K91.92320719
20BMPR1B1.89824587
21MARK11.70081883
22MINK11.61547696
23MAP2K41.56519049
24WEE11.42868771
25EPHB21.39841098
26TNIK1.39827814
27RIPK41.37015688
28NTRK21.35211748
29CAMKK21.31224102
30MAPK131.28617128
31PAK61.26769049
32PAK31.20990447
33WNK41.20238867
34TSSK61.19424652
35GRK51.16279941
36CDK51.15039086
37SIK31.14834722
38MAP4K21.14599900
39SGK2231.13387559
40SGK4941.13387559
41CAMK2A1.11410599
42PNCK1.09073560
43PRKCG1.09065229
44GRK11.07693761
45SGK21.06509964
46KSR11.05167631
47CAMK2B1.00426085
48MKNK20.99750596
49PTK2B0.98270896
50CAMK1G0.95409995
51CAMKK10.93591844
52ARAF0.91532524
53NME10.90658406
54BMPR20.89499443
55BRAF0.89005330
56PDK40.88688336
57PDK30.88688336
58CDK180.80428973
59FES0.79289417
60CSNK1G10.78813018
61CSNK1G30.78182934
62FGFR20.77503418
63BCR0.77060769
64MAPK70.74188236
65CDK150.73781608
66DAPK30.72656731
67CDK140.72179145
68PRKCE0.71830709
69EPHA30.71791967
70VRK10.70954125
71NTRK10.70809657
72KSR20.70704894
73FGR0.70319341
74CSNK1A1L0.68032376
75CAMK1D0.67888039
76DYRK30.67264629
77SGK30.65006011
78CDK30.63421668
79ERBB20.62696182
80SGK10.62405771
81CDK11A0.62281629
82UHMK10.61796486
83PRKCZ0.61451072
84MAPK120.60710635
85SIK20.60227735
86YES10.59335847
87STK160.56945845
88TAOK10.56182052
89CAMK10.55231446
90CAMK2D0.53622967
91DYRK1A0.53558988
92PHKG20.51878748
93PHKG10.51878748
94TGFBR10.51297909
95TAOK30.49898003
96PDK20.49825477
97STK110.49656099
98NUAK10.48389066
99ADRBK10.48079591
100STK390.47882613
101TNK20.47712504
102MAP3K130.47647673
103ADRBK20.46636250
104GRK70.45293711
105TRIM280.43172205
106PKN10.42665307
107CSNK1E0.42600973
108CAMK2G0.42472830
109ROCK10.42272354
110TLK10.41735549
111ROCK20.41248636
112NEK60.40699445
113WNK30.39584557
114PDPK10.38489326
115CSNK1A10.38395569
116MAP2K20.38091943
117MUSK0.36440416
118CAMK40.36439959
119CSNK1G20.36392863
120MYLK0.36023527
121PDK10.35936663
122TYRO30.35762973
123STK38L0.35144203
124CSNK1D0.34293616
125PIK3CA0.33639275
126RAF10.33579099
127PRKACA0.32941462
128INSRR0.32616510
129PRKCH0.31347240
130DYRK1B0.30925187
131ZAK0.30855457
132MAP3K20.30318731
133RPS6KA30.30302859
134CDK80.29358492
135PRKG10.27966315
136FER0.27913368
137TIE10.27558740
138FYN0.27253755
139MARK20.26550115
140PRKCA0.26025320

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.61932786
2Synaptic vesicle cycle_Homo sapiens_hsa047214.12256863
3Collecting duct acid secretion_Homo sapiens_hsa049663.17059476
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.02852170
5Morphine addiction_Homo sapiens_hsa050322.79524929
6GABAergic synapse_Homo sapiens_hsa047272.70608880
7Circadian entrainment_Homo sapiens_hsa047132.62952946
8Long-term potentiation_Homo sapiens_hsa047202.55194483
9Olfactory transduction_Homo sapiens_hsa047402.54743746
10Amphetamine addiction_Homo sapiens_hsa050312.51395383
11Glutamatergic synapse_Homo sapiens_hsa047242.47679677
12Dopaminergic synapse_Homo sapiens_hsa047282.07249801
13Salivary secretion_Homo sapiens_hsa049702.05870241
14Taste transduction_Homo sapiens_hsa047421.88571364
15Vibrio cholerae infection_Homo sapiens_hsa051101.88025945
16Insulin secretion_Homo sapiens_hsa049111.87045533
17Serotonergic synapse_Homo sapiens_hsa047261.86891193
18Renin secretion_Homo sapiens_hsa049241.86526766
19Long-term depression_Homo sapiens_hsa047301.70847158
20Calcium signaling pathway_Homo sapiens_hsa040201.60236312
21Oxytocin signaling pathway_Homo sapiens_hsa049211.59072493
22Cholinergic synapse_Homo sapiens_hsa047251.58912287
23Protein export_Homo sapiens_hsa030601.57234995
24Gastric acid secretion_Homo sapiens_hsa049711.51674447
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.50372142
26Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.49773123
27Cocaine addiction_Homo sapiens_hsa050301.46821751
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.45576525
29Oxidative phosphorylation_Homo sapiens_hsa001901.45250731
30Steroid biosynthesis_Homo sapiens_hsa001001.42673672
31Aldosterone synthesis and secretion_Homo sapiens_hsa049251.42113309
32Butanoate metabolism_Homo sapiens_hsa006501.38194750
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.37847775
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.37485785
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.35646646
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.31260744
37Basal cell carcinoma_Homo sapiens_hsa052171.28862253
38Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.23593215
39Phototransduction_Homo sapiens_hsa047441.22203276
40Nitrogen metabolism_Homo sapiens_hsa009101.19583637
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17062463
42Gap junction_Homo sapiens_hsa045401.16785795
43cAMP signaling pathway_Homo sapiens_hsa040241.10020695
44Hedgehog signaling pathway_Homo sapiens_hsa043401.06337440
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.05893433
46* Axon guidance_Homo sapiens_hsa043601.05696484
47Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04534370
48Cardiac muscle contraction_Homo sapiens_hsa042601.04337752
49GnRH signaling pathway_Homo sapiens_hsa049121.02774961
50Alzheimers disease_Homo sapiens_hsa050101.01842849
51Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01459950
52Rheumatoid arthritis_Homo sapiens_hsa053231.00331106
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.97699749
54Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.96567408
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.96136549
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.93867570
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93372389
58ErbB signaling pathway_Homo sapiens_hsa040120.92911187
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92544070
60Linoleic acid metabolism_Homo sapiens_hsa005910.89855668
61Vascular smooth muscle contraction_Homo sapiens_hsa042700.86956837
62Ribosome_Homo sapiens_hsa030100.86053035
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.84163701
64Parkinsons disease_Homo sapiens_hsa050120.80189297
65Estrogen signaling pathway_Homo sapiens_hsa049150.79607458
66Hippo signaling pathway_Homo sapiens_hsa043900.79071876
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.78139638
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77347545
69Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.77010853
70Melanogenesis_Homo sapiens_hsa049160.75727156
71Circadian rhythm_Homo sapiens_hsa047100.75202420
72Glioma_Homo sapiens_hsa052140.74937268
73Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.74515562
74Type II diabetes mellitus_Homo sapiens_hsa049300.73048453
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70862258
76MAPK signaling pathway_Homo sapiens_hsa040100.66927764
77Dilated cardiomyopathy_Homo sapiens_hsa054140.65417641
78Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65387379
79Fatty acid biosynthesis_Homo sapiens_hsa000610.64814466
80Phagosome_Homo sapiens_hsa041450.63518919
81Propanoate metabolism_Homo sapiens_hsa006400.61241427
82* Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60816121
83Tryptophan metabolism_Homo sapiens_hsa003800.60267779
84Pancreatic secretion_Homo sapiens_hsa049720.58834408
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56262937
86Basal transcription factors_Homo sapiens_hsa030220.55321187
87Ras signaling pathway_Homo sapiens_hsa040140.55020152
88Bile secretion_Homo sapiens_hsa049760.54065411
89Huntingtons disease_Homo sapiens_hsa050160.53481240
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51764054
91Fatty acid metabolism_Homo sapiens_hsa012120.51268580
92RNA polymerase_Homo sapiens_hsa030200.50479457
93Oocyte meiosis_Homo sapiens_hsa041140.49650846
94Glycerolipid metabolism_Homo sapiens_hsa005610.48862354
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48371709
96Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.48119636
97Pyruvate metabolism_Homo sapiens_hsa006200.48112197
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46277099
99Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.45187274
100Selenocompound metabolism_Homo sapiens_hsa004500.45112907
101Glucagon signaling pathway_Homo sapiens_hsa049220.43946387
102Inositol phosphate metabolism_Homo sapiens_hsa005620.43499376
103Peroxisome_Homo sapiens_hsa041460.43289057
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.42447610
105Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41514329
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.40777194
107Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40306026
108Steroid hormone biosynthesis_Homo sapiens_hsa001400.39100240
109Alcoholism_Homo sapiens_hsa050340.38395652
110Type I diabetes mellitus_Homo sapiens_hsa049400.37174680
111Fanconi anemia pathway_Homo sapiens_hsa034600.37092676
112African trypanosomiasis_Homo sapiens_hsa051430.36597359
113Choline metabolism in cancer_Homo sapiens_hsa052310.36081036
114Rap1 signaling pathway_Homo sapiens_hsa040150.35619271
115Thyroid hormone synthesis_Homo sapiens_hsa049180.34528877
116Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33765637
117Dorso-ventral axis formation_Homo sapiens_hsa043200.32507890
118Regulation of autophagy_Homo sapiens_hsa041400.32354021
119Renal cell carcinoma_Homo sapiens_hsa052110.29692865
120Wnt signaling pathway_Homo sapiens_hsa043100.28365173
121Melanoma_Homo sapiens_hsa052180.28121761
122Ether lipid metabolism_Homo sapiens_hsa005650.27510900
1232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.27245134
124Ovarian steroidogenesis_Homo sapiens_hsa049130.26981833
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.21291409
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.20793821
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.20109224
128Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.19674545
129Endocytosis_Homo sapiens_hsa041440.18349811
130Neurotrophin signaling pathway_Homo sapiens_hsa047220.17616589
131Prion diseases_Homo sapiens_hsa050200.16199856
132VEGF signaling pathway_Homo sapiens_hsa043700.14210679
133Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13883402

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