LRRC3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.40596010
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.40596010
3L-phenylalanine metabolic process (GO:0006558)7.01403531
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.01403531
5aromatic amino acid family catabolic process (GO:0009074)6.82690019
6indole-containing compound catabolic process (GO:0042436)6.32949714
7indolalkylamine catabolic process (GO:0046218)6.32949714
8tryptophan catabolic process (GO:0006569)6.32949714
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.13896241
10kynurenine metabolic process (GO:0070189)6.01673542
11tryptophan metabolic process (GO:0006568)5.96349931
12bile acid biosynthetic process (GO:0006699)5.81421267
13urea metabolic process (GO:0019627)5.69332564
14urea cycle (GO:0000050)5.69332564
15intestinal cholesterol absorption (GO:0030299)5.59627722
16high-density lipoprotein particle remodeling (GO:0034375)5.56018278
17glyoxylate metabolic process (GO:0046487)5.52888883
18negative regulation of fibrinolysis (GO:0051918)5.42062393
19alpha-linolenic acid metabolic process (GO:0036109)5.35517122
20protein carboxylation (GO:0018214)5.33168694
21peptidyl-glutamic acid carboxylation (GO:0017187)5.33168694
22regulation of fibrinolysis (GO:0051917)5.31095248
23regulation of protein activation cascade (GO:2000257)5.29628715
24complement activation, alternative pathway (GO:0006957)5.26983044
25nitrogen cycle metabolic process (GO:0071941)5.24348441
26regulation of plasminogen activation (GO:0010755)5.22014428
27positive regulation of heterotypic cell-cell adhesion (GO:0034116)5.16332217
28sulfur amino acid catabolic process (GO:0000098)5.07710371
29bile acid metabolic process (GO:0008206)5.02380539
30aromatic amino acid family metabolic process (GO:0009072)4.99151317
31regulation of complement activation (GO:0030449)4.95360205
32omega-hydroxylase P450 pathway (GO:0097267)4.93842653
33tyrosine metabolic process (GO:0006570)4.93030873
34reverse cholesterol transport (GO:0043691)4.91901705
35epoxygenase P450 pathway (GO:0019373)4.91815294
36cysteine metabolic process (GO:0006534)4.88537014
37fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.85736518
38serine family amino acid catabolic process (GO:0009071)4.84067931
39regulation of cholesterol esterification (GO:0010872)4.83432230
40bile acid and bile salt transport (GO:0015721)4.70866503
41protein-lipid complex remodeling (GO:0034368)4.70572711
42macromolecular complex remodeling (GO:0034367)4.70572711
43plasma lipoprotein particle remodeling (GO:0034369)4.70572711
44phospholipid efflux (GO:0033700)4.62526302
45homocysteine metabolic process (GO:0050667)4.61291303
46regulation of triglyceride catabolic process (GO:0010896)4.60826242
47indolalkylamine metabolic process (GO:0006586)4.59516200
48cellular ketone body metabolic process (GO:0046950)4.59140719
49triglyceride homeostasis (GO:0070328)4.53565091
50acylglycerol homeostasis (GO:0055090)4.53565091
51coenzyme catabolic process (GO:0009109)4.50704310
52alpha-amino acid catabolic process (GO:1901606)4.50418093
53cellular biogenic amine catabolic process (GO:0042402)4.48958004
54amine catabolic process (GO:0009310)4.48958004
55negative regulation of sterol transport (GO:0032372)4.35366246
56negative regulation of cholesterol transport (GO:0032375)4.35366246
57imidazole-containing compound metabolic process (GO:0052803)4.33719225
58amino-acid betaine metabolic process (GO:0006577)4.31843056
59cholesterol efflux (GO:0033344)4.25500415
60negative regulation of blood coagulation (GO:0030195)4.20053517
61negative regulation of hemostasis (GO:1900047)4.20053517
62lysine metabolic process (GO:0006553)4.17224907
63lysine catabolic process (GO:0006554)4.17224907
64benzene-containing compound metabolic process (GO:0042537)4.16278928
65cellular glucuronidation (GO:0052695)4.14679857
66cellular amino acid catabolic process (GO:0009063)4.13800651
67protein-lipid complex subunit organization (GO:0071825)4.13097354
68plasma lipoprotein particle clearance (GO:0034381)4.10575629
69glutamate metabolic process (GO:0006536)4.05262156
70regulation of apoptotic cell clearance (GO:2000425)4.03271519
71arginine metabolic process (GO:0006525)4.02410121
72cellular modified amino acid catabolic process (GO:0042219)4.02003971
73low-density lipoprotein particle remodeling (GO:0034374)3.98826975
74complement activation, classical pathway (GO:0006958)3.97980862
75fibrinolysis (GO:0042730)3.95881233
76ketone body metabolic process (GO:1902224)3.95058488
77drug catabolic process (GO:0042737)3.91043701
78dicarboxylic acid biosynthetic process (GO:0043650)3.90151409
79negative regulation of coagulation (GO:0050819)3.89622400
80plasma lipoprotein particle assembly (GO:0034377)3.86582180
81negative regulation of lipase activity (GO:0060192)3.85791810
82complement activation (GO:0006956)3.85523559
83glycine metabolic process (GO:0006544)3.82283119
84blood coagulation, intrinsic pathway (GO:0007597)3.80873189
85protein activation cascade (GO:0072376)3.79505097
86ethanol oxidation (GO:0006069)3.78980645
87pyrimidine nucleobase catabolic process (GO:0006208)3.78881500
88acute-phase response (GO:0006953)3.76583002
89negative regulation of wound healing (GO:0061045)3.75553073
90aldehyde catabolic process (GO:0046185)3.75156777
91phospholipid homeostasis (GO:0055091)3.73811107
92uronic acid metabolic process (GO:0006063)3.72760630
93glucuronate metabolic process (GO:0019585)3.72760630
94NAD biosynthetic process (GO:0009435)3.71289841
95cofactor catabolic process (GO:0051187)3.71134944
96regulation of bile acid biosynthetic process (GO:0070857)3.70869995
97positive regulation of blood coagulation (GO:0030194)3.70796833
98positive regulation of hemostasis (GO:1900048)3.70796833
99serine family amino acid metabolic process (GO:0009069)3.68777284
100cytolysis (GO:0019835)3.67479207
101organic acid catabolic process (GO:0016054)3.61424820
102carboxylic acid catabolic process (GO:0046395)3.61424820
103positive regulation of fatty acid biosynthetic process (GO:0045723)3.60650026
104positive regulation of lipoprotein lipase activity (GO:0051006)3.59587789
105positive regulation of triglyceride lipase activity (GO:0061365)3.59587789
106very-low-density lipoprotein particle assembly (GO:0034379)3.56658879
107cholesterol homeostasis (GO:0042632)3.55104571
108plasma lipoprotein particle organization (GO:0071827)3.54285724
109positive regulation of coagulation (GO:0050820)3.53118821
110positive regulation of lipid catabolic process (GO:0050996)3.51567872
111fat-soluble vitamin biosynthetic process (GO:0042362)3.49557352
112sterol homeostasis (GO:0055092)3.49015554
113nicotinamide nucleotide biosynthetic process (GO:0019359)3.48754261
114pyridine nucleotide biosynthetic process (GO:0019363)3.48754261
115exogenous drug catabolic process (GO:0042738)3.48500167
116negative regulation of protein activation cascade (GO:2000258)3.48113826
117drug metabolic process (GO:0017144)3.48005172
118cholesterol transport (GO:0030301)3.47590509
119sterol transport (GO:0015918)3.47590509
120oxidative demethylation (GO:0070989)3.44773684
121protein-lipid complex assembly (GO:0065005)3.43033541
122peptidyl-glutamic acid modification (GO:0018200)3.42221754
123lipoprotein metabolic process (GO:0042157)3.33730958
124regulation of heterotypic cell-cell adhesion (GO:0034114)3.30838371
125regulation of cholesterol homeostasis (GO:2000188)3.23882360
126regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.15125293
127intestinal absorption (GO:0050892)3.13586462
128regulation of cholesterol biosynthetic process (GO:0045540)3.11414042
129proline metabolic process (GO:0006560)3.09764265
130serine family amino acid biosynthetic process (GO:0009070)3.09667315
131regulation of humoral immune response (GO:0002920)3.09526060
132ethanol metabolic process (GO:0006067)3.09005387
133heme transport (GO:0015886)3.04484250

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse7.37199673
2* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.27715912
3* PPARA_22158963_ChIP-Seq_LIVER_Mouse6.18551217
4* LXR_22158963_ChIP-Seq_LIVER_Mouse5.78073618
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.03391572
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.28778854
7CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.96165639
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.79598055
9PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.65479568
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.36790050
11ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.30460776
12ZNF274_21170338_ChIP-Seq_K562_Hela2.14967113
13TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.13490328
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.09767229
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse10.4255476
16TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.82778988
17ZNF263_19887448_ChIP-Seq_K562_Human1.82033451
18DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.75605116
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.63755500
20HTT_18923047_ChIP-ChIP_STHdh_Human1.58560027
21SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.56833884
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54553542
23HIF1A_21447827_ChIP-Seq_MCF-7_Human1.45940009
24* FOXA2_19822575_ChIP-Seq_HepG2_Human1.45255315
25TAF15_26573619_Chip-Seq_HEK293_Human1.41515558
26HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.40120772
27KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.39019419
28KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.39019419
29KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.39019419
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.32781801
31GBX2_23144817_ChIP-Seq_PC3_Human1.30436088
32* HNF4A_19822575_ChIP-Seq_HepG2_Human1.23907805
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.22647017
34GATA1_22025678_ChIP-Seq_K562_Human1.21754429
35PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16615033
36TP53_20018659_ChIP-ChIP_R1E_Mouse1.14171878
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.13840632
38STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.12421256
39TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11394320
40VDR_22108803_ChIP-Seq_LS180_Human1.11217680
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.10635774
42SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.10228932
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.05214237
44POU5F1_16518401_ChIP-PET_MESCs_Mouse1.03931133
45ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03572491
46NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.01739705
47MYC_19829295_ChIP-Seq_ESCs_Human1.00675271
48RXRA_24833708_ChIP-Seq_LIVER_Mouse1.00158900
49PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98559961
50RNF2_18974828_ChIP-Seq_MESCs_Mouse0.98000395
51EZH2_18974828_ChIP-Seq_MESCs_Mouse0.98000395
52CBX2_27304074_Chip-Seq_ESCs_Mouse0.97756390
53PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97705488
54CLOCK_20551151_ChIP-Seq_293T_Human0.97229674
55IGF1R_20145208_ChIP-Seq_DFB_Human0.97225205
56CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96715662
57MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.95613661
58SUZ12_27294783_Chip-Seq_ESCs_Mouse0.95442535
59DNAJC2_21179169_ChIP-ChIP_NT2_Human0.95421107
60PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.93398481
61SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91889162
62OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.87281156
63EZH2_22144423_ChIP-Seq_EOC_Human0.87171623
64RNF2_27304074_Chip-Seq_NSC_Mouse0.86599213
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83471695
66SOX11_22085726_ChIP-Seq_ESNs_Mouse0.83430252
67Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.83010047
68GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.82367566
69BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82335066
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.81590325
71* RING1B_27294783_Chip-Seq_ESCs_Mouse0.81394475
72IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.80345108
73STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.79886298
74STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.78209977
75ERG_21242973_ChIP-ChIP_JURKAT_Human0.77624891
76BCAT_22108803_ChIP-Seq_LS180_Human0.77106394
77RAC3_21632823_ChIP-Seq_H3396_Human0.77024673
78NRF2_20460467_ChIP-Seq_MEFs_Mouse0.75215581
79NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.75215581
80NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.74971150
81RARB_24833708_ChIP-Seq_LIVER_Mouse0.74666811
82PIAS1_25552417_ChIP-Seq_VCAP_Human0.74633973
83EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.74529763
84CTCF_27219007_Chip-Seq_Bcells_Human0.74428567
85SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.74331096
86AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.74226229
87* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73170827
88NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.73015170
89ETV2_25802403_ChIP-Seq_MESCs_Mouse0.72810104
90ZFP57_27257070_Chip-Seq_ESCs_Mouse0.72175957
91FOXH1_21741376_ChIP-Seq_ESCs_Human0.71674487
92POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.71538798
93POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.71009400
94TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.71009400
95PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.70761709
96ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.69824494
97SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.69149780
98PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.68181559
99P300_19829295_ChIP-Seq_ESCs_Human0.68068148
100KAP1_22055183_ChIP-Seq_ESCs_Mouse0.67974286
101RAD21_21589869_ChIP-Seq_MESCs_Mouse0.67930643
102ESR2_21235772_ChIP-Seq_MCF-7_Human0.67892649
103RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.67788594
104* EZH2_27294783_Chip-Seq_ESCs_Mouse0.67232678
105PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.67086385
106ESR1_15608294_ChIP-ChIP_MCF-7_Human0.66939790
107SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.66032971
108BMI1_23680149_ChIP-Seq_NPCS_Mouse0.65992463
109NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.65952187
110SMAD3_21741376_ChIP-Seq_HESCs_Human0.65871209
111PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.64810420
112ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.63984380
113EED_16625203_ChIP-ChIP_MESCs_Mouse0.63720857
114CDX2_20551321_ChIP-Seq_CACO-2_Human0.62899982
115AUTS2_25519132_ChIP-Seq_293T-REX_Human0.61961715
116STAT1_17558387_ChIP-Seq_HELA_Human0.61855553
117* SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.61661645
118AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.60726687
119* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.59656540
120FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.58861331
121AR_21572438_ChIP-Seq_LNCaP_Human0.58301607
122ZNF217_24962896_ChIP-Seq_MCF-7_Human0.57866102
123SMAD4_21741376_ChIP-Seq_HESCs_Human0.57566187
124SUZ12_27294783_Chip-Seq_NPCs_Mouse0.57283533
125NFE2_27457419_Chip-Seq_LIVER_Mouse0.56784605
126EZH2_27294783_Chip-Seq_NPCs_Mouse0.56713959
127ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.56692373
128SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.56490156
129BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.56228879
130BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.56002229
131RUNX1_27457419_Chip-Seq_LIVER_Mouse0.55543596
132SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.55219471
133CTBP1_25329375_ChIP-Seq_LNCAP_Human0.53959805
134ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.53958923
135GATA4_25053715_ChIP-Seq_YYC3_Human0.53894225
136IRF1_19129219_ChIP-ChIP_H3396_Human0.53623645
137EGR1_19032775_ChIP-ChIP_M12_Human0.53564053
138MTF2_20144788_ChIP-Seq_MESCs_Mouse0.53532374
139SOX2_27498859_Chip-Seq_STOMACH_Mouse0.53517351
140NR3C1_21868756_ChIP-Seq_MCF10A_Human0.53406101
141NR3C1_23031785_ChIP-Seq_PC12_Mouse0.53070766
142ESR1_21235772_ChIP-Seq_MCF-7_Human0.52763944
143CTBP2_25329375_ChIP-Seq_LNCAP_Human0.52694738
144KDM2B_26808549_Chip-Seq_REH_Human0.52021345
145* OCT4_21477851_ChIP-Seq_ESCs_Mouse0.51940750
146RARA_24833708_ChIP-Seq_LIVER_Mouse0.51597629
147SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.51349809
148JARID2_20075857_ChIP-Seq_MESCs_Mouse0.51080284
149IRF8_22096565_ChIP-ChIP_GC-B_Human0.50643634
150AR_20517297_ChIP-Seq_VCAP_Human0.50167373
151* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.50024784
152UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.49369052
153SMAD4_21799915_ChIP-Seq_A2780_Human0.49353111
154TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.49064174
155EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.48954381
156RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.48512423
157MYC_19915707_ChIP-ChIP_AK7_Human0.48213904
158CRX_20693478_ChIP-Seq_RETINA_Mouse0.48143094
159REST_21632747_ChIP-Seq_MESCs_Mouse0.48023870
160SMAD4_21741376_ChIP-Seq_EPCs_Human0.47884223
161SALL4_18804426_ChIP-ChIP_XEN_Mouse0.46792575
162CBP_21632823_ChIP-Seq_H3396_Human0.46241432

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.20418407
2MP0005360_urolithiasis7.42093008
3MP0005085_abnormal_gallbladder_physiolo6.61605343
4MP0005365_abnormal_bile_salt6.16874319
5MP0008875_abnormal_xenobiotic_pharmacok5.01641736
6MP0003252_abnormal_bile_duct4.09493748
7MP0003122_maternal_imprinting3.98218696
8MP0010329_abnormal_lipoprotein_level3.54979956
9MP0003806_abnormal_nucleotide_metabolis3.51789757
10MP0009840_abnormal_foam_cell3.07748684
11MP0005083_abnormal_biliary_tract2.87386363
12MP0003191_abnormal_cellular_cholesterol2.65843154
13MP0005332_abnormal_amino_acid2.62186233
14MP0003195_calcinosis2.57470524
15MP0001666_abnormal_nutrient_absorption2.41437718
16MP0004019_abnormal_vitamin_homeostasis2.23936061
17MP0004133_heterotaxia2.15866341
18MP0002118_abnormal_lipid_homeostasis2.05825055
19MP0003868_abnormal_feces_composition2.05560595
20MP0000609_abnormal_liver_physiology2.04395329
21MP0002138_abnormal_hepatobiliary_system1.87443038
22MP0009697_abnormal_copulation1.81484435
23MP0005058_abnormal_lysosome_morphology1.75862585
24MP0002089_abnormal_postnatal_growth/wei1.69527939
25MP0005319_abnormal_enzyme/_coenzyme1.67112952
26MP0001764_abnormal_homeostasis1.62721950
27MP0005257_abnormal_intraocular_pressure1.58763838
28MP0005584_abnormal_enzyme/coenzyme_acti1.51147405
29MP0003283_abnormal_digestive_organ1.48760759
30MP0006292_abnormal_olfactory_placode1.48550598
31MP0003121_genomic_imprinting1.39291458
32MP0005451_abnormal_body_composition1.31982302
33MP0005647_abnormal_sex_gland1.31858865
34MP0001529_abnormal_vocalization1.31811806
35MP0005167_abnormal_blood-brain_barrier1.28475005
36MP0003011_delayed_dark_adaptation1.27527519
37MP0005394_taste/olfaction_phenotype1.24314806
38MP0005499_abnormal_olfactory_system1.24314806
39MP0002822_catalepsy1.22849460
40MP0002938_white_spotting1.22801987
41MP0001915_intracranial_hemorrhage1.19740168
42MP0003890_abnormal_embryonic-extraembry1.12834568
43MP0002254_reproductive_system_inflammat1.11833745
44MP0009764_decreased_sensitivity_to1.09795557
45MP0006054_spinal_hemorrhage1.09164318
46MP0009643_abnormal_urine_homeostasis1.09158664
47MP0003656_abnormal_erythrocyte_physiolo1.06108632
48MP0003136_yellow_coat_color1.04266797
49MP0000598_abnormal_liver_morphology1.02807374
50MP0002876_abnormal_thyroid_physiology1.01138955
51MP0003186_abnormal_redox_activity0.99043746
52MP0000604_amyloidosis0.98052435
53MP0003123_paternal_imprinting0.96284377
54MP0002233_abnormal_nose_morphology0.95140849
55MP0003119_abnormal_digestive_system0.94438737
56MP0001293_anophthalmia0.93775914
57MP0002697_abnormal_eye_size0.91642975
58MP0002909_abnormal_adrenal_gland0.91106794
59MP0009763_increased_sensitivity_to0.88667632
60MP0009642_abnormal_blood_homeostasis0.88574381
61MP0002282_abnormal_trachea_morphology0.87976324
62MP0005535_abnormal_body_temperature0.87916112
63MP0005084_abnormal_gallbladder_morpholo0.86189092
64MP0002653_abnormal_ependyma_morphology0.84993782
65MP0008469_abnormal_protein_level0.84912376
66MP0010368_abnormal_lymphatic_system0.84233882
67MP0005636_abnormal_mineral_homeostasis0.84215041
68MP0002928_abnormal_bile_duct0.82821266
69MP0004272_abnormal_basement_membrane0.82107862
70MP0005670_abnormal_white_adipose0.81177363
71MP0003385_abnormal_body_wall0.80985594
72MP0002078_abnormal_glucose_homeostasis0.79942055
73MP0003690_abnormal_glial_cell0.78286233
74MP0005334_abnormal_fat_pad0.76766763
75MP0006276_abnormal_autonomic_nervous0.76441423
76MP0005379_endocrine/exocrine_gland_phen0.74062334
77MP0003567_abnormal_fetal_cardiomyocyte0.74038069
78MP0005376_homeostasis/metabolism_phenot0.72363129
79MP0002092_abnormal_eye_morphology0.72252217
80MP0009053_abnormal_anal_canal0.72239005
81MP0009765_abnormal_xenobiotic_induced0.71291678
82MP0008789_abnormal_olfactory_epithelium0.71278301
83MP0004142_abnormal_muscle_tone0.68161063
84MP0005551_abnormal_eye_electrophysiolog0.67772085
85MP0000639_abnormal_adrenal_gland0.66634971
86MP0005448_abnormal_energy_balance0.65974711
87MP0000778_abnormal_nervous_system0.65906478
88MP0005220_abnormal_exocrine_pancreas0.65839333
89MP0002249_abnormal_larynx_morphology0.65414856
90MP0003303_peritoneal_inflammation0.65157677
91MP0005187_abnormal_penis_morphology0.64906381
92MP0004782_abnormal_surfactant_physiolog0.64594146
93MP0001756_abnormal_urination0.64375978
94MP0008874_decreased_physiological_sensi0.64238494
95MP0006082_CNS_inflammation0.64040561
96MP0003942_abnormal_urinary_system0.63984355
97MP0005464_abnormal_platelet_physiology0.62952477
98MP0010030_abnormal_orbit_morphology0.61994657
99MP0005377_hearing/vestibular/ear_phenot0.61825331
100MP0003878_abnormal_ear_physiology0.61825331
101MP0008872_abnormal_physiological_respon0.61056442
102MP0005408_hypopigmentation0.60234773
103MP0004883_abnormal_blood_vessel0.59497223
104MP0000049_abnormal_middle_ear0.59371158
105MP0003632_abnormal_nervous_system0.59193098
106MP0002971_abnormal_brown_adipose0.58921639
107MP0000538_abnormal_urinary_bladder0.58397688
108MP0004130_abnormal_muscle_cell0.57540949
109MP0005195_abnormal_posterior_eye0.56519627
110MP0002557_abnormal_social/conspecific_i0.55304499
111MP0003937_abnormal_limbs/digits/tail_de0.55245620
112MP0003938_abnormal_ear_development0.54788580
113MP0000566_synostosis0.53619439
114MP0003329_amyloid_beta_deposits0.53107509
115MP0003953_abnormal_hormone_level0.52852356
116MP0003638_abnormal_response/metabolism_0.52595179
117MP0003315_abnormal_perineum_morphology0.51417656
118MP0001286_abnormal_eye_development0.51384547
119MP0002184_abnormal_innervation0.51331184
120MP0003075_altered_response_to0.51013456
121MP0002111_abnormal_tail_morphology0.50865601
122MP0005646_abnormal_pituitary_gland0.49500937
123MP0000371_diluted_coat_color0.49474402
124MP0002090_abnormal_vision0.48993953
125MP0005166_decreased_susceptibility_to0.48729730
126MP0003724_increased_susceptibility_to0.48325167
127MP0006036_abnormal_mitochondrial_physio0.46021372
128MP0005391_vision/eye_phenotype0.45964576
129MP0005266_abnormal_metabolism0.45789998
130MP0000955_abnormal_spinal_cord0.45779488
131MP0000026_abnormal_inner_ear0.45643900
132MP0003705_abnormal_hypodermis_morpholog0.42249810
133MP0009672_abnormal_birth_weight0.39301836
134MP0002136_abnormal_kidney_physiology0.39084207
135MP0005395_other_phenotype0.38987789
136MP0000230_abnormal_systemic_arterial0.38378802
137MP0006035_abnormal_mitochondrial_morpho0.37448220
138MP0002132_abnormal_respiratory_system0.37227105
139MP0008873_increased_physiological_sensi0.37043604
140MP0004381_abnormal_hair_follicle0.36814672
141MP0003718_maternal_effect0.36265475
142MP0001661_extended_life_span0.34840524
143MP0001984_abnormal_olfaction0.34691296
144MP0002069_abnormal_eating/drinking_beha0.34654268
145MP0000579_abnormal_nail_morphology0.32461056
146MP0005248_abnormal_Harderian_gland0.32087107
147MP0009115_abnormal_fat_cell0.31018031
148MP0001324_abnormal_eye_pigmentation0.30790791
149MP0001502_abnormal_circadian_rhythm0.30418700
150MP0000249_abnormal_blood_vessel0.30020736
151MP0005595_abnormal_vascular_smooth0.29483918
152MP0003633_abnormal_nervous_system0.29073677
153MP0005164_abnormal_response_to0.28432314
154MP0005197_abnormal_uvea_morphology0.26896031
155MP0003172_abnormal_lysosome_physiology0.25610787

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.22295002
2Deep venous thrombosis (HP:0002625)7.17176626
3Intrahepatic cholestasis (HP:0001406)7.06556530
4Prolonged partial thromboplastin time (HP:0003645)6.67813641
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.45466196
6Complement deficiency (HP:0004431)6.35588428
7Hypobetalipoproteinemia (HP:0003563)6.12357470
8Xanthomatosis (HP:0000991)5.93904817
9Hyperlipoproteinemia (HP:0010980)5.34993124
10Joint hemorrhage (HP:0005261)4.98676332
11Hypolipoproteinemia (HP:0010981)4.58196996
12Abnormality of complement system (HP:0005339)4.54645959
13Epidermoid cyst (HP:0200040)4.40684834
14Hyperammonemia (HP:0001987)4.35764338
15Hyperglycinemia (HP:0002154)4.30481512
16Systemic lupus erythematosus (HP:0002725)4.26044881
17Abnormality of the common coagulation pathway (HP:0010990)4.22383430
18Conjugated hyperbilirubinemia (HP:0002908)4.21925982
19Abnormality of glutamine family amino acid metabolism (HP:0010902)4.18972577
20Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.15539955
21Ketosis (HP:0001946)4.10869726
22Abnormality of methionine metabolism (HP:0010901)4.09834946
23Abnormality of sulfur amino acid metabolism (HP:0004339)4.05540362
24Hypoalphalipoproteinemia (HP:0003233)4.03587810
25Fat malabsorption (HP:0002630)4.00571448
26Abnormality of aspartate family amino acid metabolism (HP:0010899)3.93814514
27Abnormality of pyrimidine metabolism (HP:0004353)3.82382148
28Glomerulonephritis (HP:0000099)3.69221026
29Abnormality of glycine metabolism (HP:0010895)3.62642204
30Abnormality of serine family amino acid metabolism (HP:0010894)3.62642204
31Hyperglycinuria (HP:0003108)3.61171399
32Abnormality of the intrinsic pathway (HP:0010989)3.55976432
33Hypoglycemic coma (HP:0001325)3.38819966
34Hypercholesterolemia (HP:0003124)3.36799577
35Delayed CNS myelination (HP:0002188)3.17804928
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.16838863
37Hyperbilirubinemia (HP:0002904)3.15111876
38Abnormality of fatty-acid metabolism (HP:0004359)3.09362059
39Abnormality of serum amino acid levels (HP:0003112)2.97824970
40Steatorrhea (HP:0002570)2.97412255
41Hypochromic microcytic anemia (HP:0004840)2.95183922
42Abnormality of nucleobase metabolism (HP:0010932)2.94178801
43Spontaneous abortion (HP:0005268)2.88744304
44Hepatocellular carcinoma (HP:0001402)2.85977951
45Ketoacidosis (HP:0001993)2.82188011
46Myocardial infarction (HP:0001658)2.74771101
47Metabolic acidosis (HP:0001942)2.67842751
48Vascular calcification (HP:0004934)2.62870648
49Skin nodule (HP:0200036)2.61473550
50Bifid scrotum (HP:0000048)2.57685813
51Recurrent gram-negative bacterial infections (HP:0005420)2.55391484
52Amyloidosis (HP:0011034)2.52714907
53Abnormality of purine metabolism (HP:0004352)2.50077128
54Hypoglycemic seizures (HP:0002173)2.49625274
55Mitral stenosis (HP:0001718)2.45875515
56Enlarged kidneys (HP:0000105)2.39344611
57Lethargy (HP:0001254)2.39225129
58Neonatal onset (HP:0003623)2.36650622
59Broad alveolar ridges (HP:0000187)2.32735969
60Irritability (HP:0000737)2.31945968
61Acanthocytosis (HP:0001927)2.31190785
62Vacuolated lymphocytes (HP:0001922)2.29441904
63Sensorimotor neuropathy (HP:0007141)2.28350172
64Retinal atrophy (HP:0001105)2.28328806
65Cardiovascular calcification (HP:0011915)2.26833338
66Dicarboxylic aciduria (HP:0003215)2.26472478
67Abnormality of dicarboxylic acid metabolism (HP:0010995)2.26472478
68Gout (HP:0001997)2.25131038
69Nephritis (HP:0000123)2.23795634
70Purpura (HP:0000979)2.23019210
71Abnormal gallbladder physiology (HP:0012438)2.22709692
72Cholecystitis (HP:0001082)2.22709692
73Abnormal gallbladder morphology (HP:0012437)2.20370640
74Abnormality of the lumbar spine (HP:0100712)2.19582864
75Menorrhagia (HP:0000132)2.18297102
76Cerebral edema (HP:0002181)2.17170870
77Gingival bleeding (HP:0000225)2.15690320
78Arthropathy (HP:0003040)2.12578949
79Opisthotonus (HP:0002179)2.11563903
80Increased serum pyruvate (HP:0003542)2.11190946
81Vaginal fistula (HP:0004320)2.10783783
82Cholelithiasis (HP:0001081)2.10205003
83Glycosuria (HP:0003076)2.10152590
84Abnormality of urine glucose concentration (HP:0011016)2.10152590
85Pancreatitis (HP:0001733)2.02830595
86Status epilepticus (HP:0002133)2.02486107
87Hypophosphatemic rickets (HP:0004912)2.01595265
88Malnutrition (HP:0004395)2.01575197
89Rickets (HP:0002748)1.99062920
90Brushfield spots (HP:0001088)1.98068921
91Thrombophlebitis (HP:0004418)1.97903511
92Abnormality of mucopolysaccharide metabolism (HP:0011020)1.97475275
93Abnormality of polysaccharide metabolism (HP:0011012)1.97475275
94Abnormality of glycosaminoglycan metabolism (HP:0004371)1.97475275
95Hydroxyprolinuria (HP:0003080)1.97244741
96Abnormality of proline metabolism (HP:0010907)1.97244741
97Abnormality of the vitreous humor (HP:0004327)1.95218891
98Vomiting (HP:0002013)1.94493267
99Spastic diplegia (HP:0001264)1.93819371
100Osteomalacia (HP:0002749)1.93569083
101Esophageal varix (HP:0002040)1.92335044
102Hepatoblastoma (HP:0002884)1.92039489
103Hemorrhage of the eye (HP:0011885)1.90879501
104Urinary glycosaminoglycan excretion (HP:0003541)1.88782974
105Mucopolysacchariduria (HP:0008155)1.88782974
106Alkalosis (HP:0001948)1.87938183
107Abnormality of the gallbladder (HP:0005264)1.87715925
108Renal cortical cysts (HP:0000803)1.86988710
109Abnormality of glycolysis (HP:0004366)1.85576388
110Late onset (HP:0003584)1.85296825
111Abnormal tarsal ossification (HP:0008369)1.82677947
112Generalized aminoaciduria (HP:0002909)1.81788559
113Hyperphosphaturia (HP:0003109)1.80818060
114Fair hair (HP:0002286)1.80209811
115Neonatal hypoglycemia (HP:0001998)1.79965315
116Upper motor neuron abnormality (HP:0002127)1.79124871
117Abnormal enzyme/coenzyme activity (HP:0012379)1.78461645
118Abnormal biliary tract physiology (HP:0012439)1.78181395
119Bile duct proliferation (HP:0001408)1.78181395
120Poikilocytosis (HP:0004447)1.75278368
121Abnormality of vitamin metabolism (HP:0100508)1.72680745
122Hyperinsulinemic hypoglycemia (HP:0000825)1.72257418
123Small epiphyses (HP:0010585)1.66935132
124Neurofibrillary tangles (HP:0002185)1.64992246
125Vitreoretinal degeneration (HP:0000655)1.60654648
126Recurrent corneal erosions (HP:0000495)1.58503701
127Lissencephaly (HP:0001339)1.58247504
128Myelomeningocele (HP:0002475)1.57954197
129Trigonocephaly (HP:0000243)1.55462637
130Abnormality of carpal bone ossification (HP:0006257)1.54451288
131Epiphyseal dysplasia (HP:0002656)1.53278151
132Abnormal urine phosphate concentration (HP:0012599)1.53103718
133Pendular nystagmus (HP:0012043)1.52510367
134Mesangial abnormality (HP:0001966)1.52247714
135Bifid tongue (HP:0010297)1.46956371
136Humeroradial synostosis (HP:0003041)1.45261909
137Synostosis involving the elbow (HP:0003938)1.45261909
138Hypoplasia of the capital femoral epiphysis (HP:0003090)1.44763884
139Abnormality of the nasal septum (HP:0000419)1.44544119
140Potter facies (HP:0002009)1.44124487
141Facial shape deformation (HP:0011334)1.44124487
142Irregular epiphyses (HP:0010582)1.43403072
143Hypothermia (HP:0002045)1.42665274
144Prominent supraorbital ridges (HP:0000336)1.41868185

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.21068376
2SIK13.87162180
3FGFR43.59837207
4MAP3K93.50722489
5WNK43.34592929
6INSRR3.11065170
7ERN13.01654834
8MAP2K42.84834149
9MAPK152.80981214
10TGFBR22.74538975
11TNIK2.46678267
12ERBB42.45271149
13DDR22.40439607
14TYRO32.32772615
15TAOK32.17229527
16MAP4K22.15200228
17DAPK22.07900741
18MATK2.00327460
19GRK71.81520866
20BCR1.80923065
21MARK11.77097618
22SIK31.74129554
23FGFR31.69047854
24TRIM281.65017091
25PIK3CG1.56291896
26TYK21.53583660
27MAPK111.40061815
28MST1R1.38629241
29SGK21.33694222
30MAP3K41.32477379
31MAP2K71.32423551
32FRK1.32290526
33MAPK121.30417218
34PIM21.29647604
35SIK21.26572750
36FGFR11.25108887
37CASK1.22150793
38MAPK41.18580125
39FGFR21.17573068
40WNK31.14498342
41CSF1R1.14266363
42RIPK11.14097616
43MAP3K111.12774805
44FGR1.11520563
45PRKCZ1.10634706
46CAMK1D1.06895821
47CHUK1.05828061
48ADRBK21.05812562
49DYRK31.04415366
50DYRK1B1.03347324
51SGK31.01246994
52PRKAA20.99628411
53CDK120.98681022
54JAK10.98186670
55ERBB20.96030161
56JAK20.94942005
57SGK2230.94938550
58SGK4940.94938550
59STK38L0.94004743
60MAP3K140.93968681
61LATS10.93510679
62NME20.92259059
63EPHA40.91174755
64PINK10.90076474
65MAP2K60.88381141
66FLT30.86764676
67IRAK30.86397513
68NEK90.86306643
69ZAK0.85869295
70MAP3K60.84967613
71MAPK70.83641582
72ABL20.79807283
73PKN10.79605973
74PDGFRA0.77921198
75CAMK40.76669144
76CSNK1G20.75238501
77CAMK1G0.73245052
78PRKD30.72379784
79AKT30.72367496
80EPHB20.71758872
81PTK60.71155633
82MAP3K70.71112648
83CSNK1G10.70933361
84ARAF0.69446260
85PRKACG0.69098122
86PRKAA10.65662653
87TIE10.65547974
88TLK10.64937284
89TBK10.64471265
90MAP2K30.64062768
91PKN20.62535299
92CSNK1G30.62307888
93GRK50.61501669
94CSNK1E0.60817171
95GSK3A0.59423339
96TAF10.59160946
97CAMK2G0.59102407
98PRKCG0.58178450
99TAOK20.58160496
100NTRK20.58055830
101ACVR1B0.56566828
102LATS20.56317297
103IGF1R0.56123777
104CSNK1D0.56086960
105IKBKB0.55143402
106CDK150.54997105
107TRIB30.54650971
108CDK11A0.53479012
109CDK180.53071668
110MAPK130.52423564
111IRAK20.51148161
112DYRK20.51075414
113NEK20.50567052
114BMPR1B0.50065760
115GRK10.49737735
116ICK0.48847185
117MINK10.47165523
118EPHA30.46812727
119MAP2K10.46344745
120MAP2K20.46287335
121MAP3K50.46083269
122EIF2AK20.44533134
123CSNK2A10.44292815
124PHKG20.43556247
125PHKG10.43556247
126MAP3K30.43194280
127MAP3K120.41911866
128RPS6KB10.41864355
129CDK140.41538776
130RET0.40675843
131GRK60.40491814
132CSNK1A1L0.40398192
133RPS6KA20.38737412
134CDK30.38219100
135MAPKAPK50.37855952
136CDC42BPA0.37745037
137CDK70.36128055
138IRAK10.35838527
139RPS6KA10.35827511
140MAP3K130.35137351
141VRK20.34950462
142CDK50.33184141
143CSNK1A10.32678269
144PDPK10.31934930
145STK390.31816624
146CDK60.30006227
147PRKG10.28579690
148CAMK2A0.28060592

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.58936450
2Nitrogen metabolism_Homo sapiens_hsa009103.44337338
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.28159247
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.23660870
5Arginine biosynthesis_Homo sapiens_hsa002203.01455432
6Complement and coagulation cascades_Homo sapiens_hsa046102.96804750
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.77559196
8Tryptophan metabolism_Homo sapiens_hsa003802.75985973
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.46223432
10Fatty acid degradation_Homo sapiens_hsa000712.38590444
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.36949282
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.31740825
13Butanoate metabolism_Homo sapiens_hsa006502.27019976
14Pentose and glucuronate interconversions_Homo sapiens_hsa000402.24627080
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.19411148
16Staphylococcus aureus infection_Homo sapiens_hsa051502.13546947
17Peroxisome_Homo sapiens_hsa041462.10015813
18Steroid hormone biosynthesis_Homo sapiens_hsa001402.05638350
19Histidine metabolism_Homo sapiens_hsa003401.96938397
20Chemical carcinogenesis_Homo sapiens_hsa052041.96658636
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.93624897
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.86616103
23PPAR signaling pathway_Homo sapiens_hsa033201.80945360
24Fatty acid metabolism_Homo sapiens_hsa012121.76517638
25Propanoate metabolism_Homo sapiens_hsa006401.75966023
26Retinol metabolism_Homo sapiens_hsa008301.72456579
27Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.72271181
28beta-Alanine metabolism_Homo sapiens_hsa004101.71274885
29Phenylalanine metabolism_Homo sapiens_hsa003601.69135183
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.67598612
31Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.64565850
32Tyrosine metabolism_Homo sapiens_hsa003501.59575297
33Bile secretion_Homo sapiens_hsa049761.54018504
34Caffeine metabolism_Homo sapiens_hsa002321.53997498
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.44892145
36Selenocompound metabolism_Homo sapiens_hsa004501.38477244
37Sulfur metabolism_Homo sapiens_hsa009201.33851306
38Fatty acid elongation_Homo sapiens_hsa000621.32970577
39ABC transporters_Homo sapiens_hsa020101.32570428
40Starch and sucrose metabolism_Homo sapiens_hsa005001.29332075
41Steroid biosynthesis_Homo sapiens_hsa001001.28590009
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.28311754
43Pyruvate metabolism_Homo sapiens_hsa006201.20648452
442-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19512271
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.11118214
46Maturity onset diabetes of the young_Homo sapiens_hsa049501.08179007
47Fat digestion and absorption_Homo sapiens_hsa049751.06540165
48Folate biosynthesis_Homo sapiens_hsa007900.99325454
49Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92687871
50Cyanoamino acid metabolism_Homo sapiens_hsa004600.92637337
51Vitamin digestion and absorption_Homo sapiens_hsa049770.92603219
52Biosynthesis of amino acids_Homo sapiens_hsa012300.89960828
53Arginine and proline metabolism_Homo sapiens_hsa003300.88599434
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88006193
55Carbon metabolism_Homo sapiens_hsa012000.83591263
56Lysine degradation_Homo sapiens_hsa003100.80548993
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.80449994
58Vitamin B6 metabolism_Homo sapiens_hsa007500.78183005
59Sulfur relay system_Homo sapiens_hsa041220.76977743
60Prion diseases_Homo sapiens_hsa050200.67592052
61Glycerolipid metabolism_Homo sapiens_hsa005610.60508176
62One carbon pool by folate_Homo sapiens_hsa006700.56215674
63Protein export_Homo sapiens_hsa030600.54192827
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49843296
65Glutathione metabolism_Homo sapiens_hsa004800.49133809
66Fatty acid biosynthesis_Homo sapiens_hsa000610.43649178
67Metabolic pathways_Homo sapiens_hsa011000.43419774
68Sphingolipid metabolism_Homo sapiens_hsa006000.41273666
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35803482
70N-Glycan biosynthesis_Homo sapiens_hsa005100.34487262
71Basal cell carcinoma_Homo sapiens_hsa052170.34434110
72Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29073844
73Glycosaminoglycan degradation_Homo sapiens_hsa005310.27178563
74Pentose phosphate pathway_Homo sapiens_hsa000300.27077935
75Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.23874465
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.20009134
77Galactose metabolism_Homo sapiens_hsa000520.19414414
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.18688472
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18134465
80Oxidative phosphorylation_Homo sapiens_hsa001900.17490748
81Insulin resistance_Homo sapiens_hsa049310.17466653
82Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17048153
83Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.15067871
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.14499692
85Fructose and mannose metabolism_Homo sapiens_hsa000510.14185426
86Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.12609409
87TGF-beta signaling pathway_Homo sapiens_hsa043500.12185483
88Glucagon signaling pathway_Homo sapiens_hsa049220.11627311
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.11007487
90Phototransduction_Homo sapiens_hsa047440.10638498
91Linoleic acid metabolism_Homo sapiens_hsa005910.10426019
92Renin-angiotensin system_Homo sapiens_hsa046140.09950121
93Axon guidance_Homo sapiens_hsa043600.07815481
94Vibrio cholerae infection_Homo sapiens_hsa051100.07094313
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.03594452
96Hepatitis C_Homo sapiens_hsa05160-0.1820183
97GABAergic synapse_Homo sapiens_hsa04727-0.1787586
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603-0.1750134
99Lysosome_Homo sapiens_hsa04142-0.1733946
100Ether lipid metabolism_Homo sapiens_hsa00565-0.1695762
101Type II diabetes mellitus_Homo sapiens_hsa04930-0.1684911
102Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1682528
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080-0.1638867
104Cocaine addiction_Homo sapiens_hsa05030-0.1625332
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1605402
106Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1296738
107Pertussis_Homo sapiens_hsa05133-0.1253176
108Other glycan degradation_Homo sapiens_hsa00511-0.1209412
109Insulin signaling pathway_Homo sapiens_hsa04910-0.0824635
110Regulation of autophagy_Homo sapiens_hsa04140-0.0640911
111AMPK signaling pathway_Homo sapiens_hsa04152-0.0447940
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0388784
113African trypanosomiasis_Homo sapiens_hsa05143-0.0140139
114Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0050410

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