LLPH

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)6.93187647
2viral transcription (GO:0019083)6.85141240
3ribosomal small subunit assembly (GO:0000028)6.65072861
4translational termination (GO:0006415)6.63141234
5maturation of SSU-rRNA (GO:0030490)6.12105145
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.81026220
7cotranslational protein targeting to membrane (GO:0006613)5.73481063
8protein targeting to ER (GO:0045047)5.71591889
9translational elongation (GO:0006414)5.65942767
10ribosomal large subunit biogenesis (GO:0042273)5.63419965
11establishment of protein localization to endoplasmic reticulum (GO:0072599)5.43845442
12protein localization to endoplasmic reticulum (GO:0070972)5.43447543
13DNA deamination (GO:0045006)5.31807400
14translational initiation (GO:0006413)5.26521721
15viral life cycle (GO:0019058)5.24494212
16cellular protein complex disassembly (GO:0043624)5.17886850
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.12656624
18proteasome assembly (GO:0043248)4.97386811
19ribonucleoprotein complex biogenesis (GO:0022613)4.79247310
20termination of RNA polymerase III transcription (GO:0006386)4.51084430
21transcription elongation from RNA polymerase III promoter (GO:0006385)4.51084430
22translation (GO:0006412)4.45946727
23protein complex disassembly (GO:0043241)4.41733140
24macromolecular complex disassembly (GO:0032984)4.20472856
25formation of translation preinitiation complex (GO:0001731)4.11934165
26rRNA processing (GO:0006364)4.11147133
27respiratory chain complex IV assembly (GO:0008535)3.97974727
28rRNA metabolic process (GO:0016072)3.96707093
29cellular component biogenesis (GO:0044085)3.96388969
30mitochondrial respiratory chain complex I assembly (GO:0032981)3.90819035
31NADH dehydrogenase complex assembly (GO:0010257)3.90819035
32mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.90819035
33negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.88051700
34mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.86529192
35nuclear-transcribed mRNA catabolic process (GO:0000956)3.85865484
36protein complex biogenesis (GO:0070271)3.83093439
37protein targeting to membrane (GO:0006612)3.73952185
38rRNA modification (GO:0000154)3.71993566
39ribosome biogenesis (GO:0042254)3.69833051
40pseudouridine synthesis (GO:0001522)3.69434729
41mitochondrial respiratory chain complex assembly (GO:0033108)3.67497726
42mRNA catabolic process (GO:0006402)3.66571402
43energy coupled proton transport, down electrochemical gradient (GO:0015985)3.63796194
44ATP synthesis coupled proton transport (GO:0015986)3.63796194
45water-soluble vitamin biosynthetic process (GO:0042364)3.63589240
46mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.63294353
47telomere maintenance via semi-conservative replication (GO:0032201)3.62873474
48DNA strand elongation involved in DNA replication (GO:0006271)3.62032175
497-methylguanosine mRNA capping (GO:0006370)3.60396635
50negative regulation of ligase activity (GO:0051352)3.58018375
51negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.58018375
52DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.56891715
53positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.56569185
547-methylguanosine RNA capping (GO:0009452)3.55688647
55RNA capping (GO:0036260)3.55688647
56spliceosomal snRNP assembly (GO:0000387)3.51670049
57regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.51475523
58intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.50237513
59signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.50237513
60regulation of cellular amino acid metabolic process (GO:0006521)3.49661297
61signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.49143839
62signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.49143839
63signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.49143839
64antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.47873596
65RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.47089592
66ribosome assembly (GO:0042255)3.46304076
67RNA catabolic process (GO:0006401)3.45026717
68establishment of protein localization to mitochondrial membrane (GO:0090151)3.44746754
69DNA strand elongation (GO:0022616)3.44337943
70anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.44010475
71cytochrome complex assembly (GO:0017004)3.42999591
72transcription elongation from RNA polymerase I promoter (GO:0006362)3.42167553
73protein neddylation (GO:0045116)3.41609786
74signal peptide processing (GO:0006465)3.40589080
75signal transduction involved in DNA damage checkpoint (GO:0072422)3.40308320
76signal transduction involved in DNA integrity checkpoint (GO:0072401)3.40308320
77detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.38483606
78termination of RNA polymerase I transcription (GO:0006363)3.38043194
79exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.36929219
80tryptophan catabolic process (GO:0006569)3.35691911
81indole-containing compound catabolic process (GO:0042436)3.35691911
82indolalkylamine catabolic process (GO:0046218)3.35691911
83signal transduction involved in cell cycle checkpoint (GO:0072395)3.35650977
84spliceosomal complex assembly (GO:0000245)3.35575587
85DNA double-strand break processing (GO:0000729)3.34249151
86nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.32018403
87transcription from RNA polymerase I promoter (GO:0006360)3.31205295
88double-strand break repair via homologous recombination (GO:0000724)3.30781353
89recombinational repair (GO:0000725)3.30618589
90antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.29204515
91chaperone-mediated protein transport (GO:0072321)3.28339491
92tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.28034512
93RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.28034512
94DNA replication initiation (GO:0006270)3.26220459
95deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.26024020
96kynurenine metabolic process (GO:0070189)3.25359465
97establishment of integrated proviral latency (GO:0075713)3.24147303
98protein-cofactor linkage (GO:0018065)3.23842242
99indolalkylamine metabolic process (GO:0006586)3.21401260
100transcription-coupled nucleotide-excision repair (GO:0006283)3.20589467
101telomere maintenance via recombination (GO:0000722)3.19819692
102platelet dense granule organization (GO:0060155)3.17860809
103DNA replication checkpoint (GO:0000076)3.17762833
104tRNA processing (GO:0008033)3.16115386
105regulation of mitotic spindle checkpoint (GO:1903504)3.13650715
106regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.13650715
107L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.13220842
108cullin deneddylation (GO:0010388)3.12317021
109electron transport chain (GO:0022900)3.11120957
110replication fork processing (GO:0031297)3.09847974
111respiratory electron transport chain (GO:0022904)3.09320875
112nucleobase biosynthetic process (GO:0046112)3.06971357
113positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.06108267
114negative regulation of DNA-dependent DNA replication (GO:2000104)3.04971500
115GTP biosynthetic process (GO:0006183)3.04602719
116purine nucleobase biosynthetic process (GO:0009113)3.03119206
117protein targeting to mitochondrion (GO:0006626)3.03015274
118regulation of mitochondrial translation (GO:0070129)3.02327991
119ncRNA processing (GO:0034470)3.01741691
120CENP-A containing nucleosome assembly (GO:0034080)3.01483775
121protein deneddylation (GO:0000338)3.01226839
122establishment of protein localization to mitochondrion (GO:0072655)2.99018352
123DNA damage response, detection of DNA damage (GO:0042769)2.98036896
124tryptophan metabolic process (GO:0006568)2.97415743
125positive regulation of ligase activity (GO:0051351)2.97213204
126somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.94370964
127somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.94370964
128isotype switching (GO:0045190)2.94370964
129fucose catabolic process (GO:0019317)2.93290446
130L-fucose metabolic process (GO:0042354)2.93290446
131L-fucose catabolic process (GO:0042355)2.93290446
132protein K6-linked ubiquitination (GO:0085020)2.91045285
133chromatin remodeling at centromere (GO:0031055)2.90670834
134DNA catabolic process, exonucleolytic (GO:0000738)2.90637033
135peptidyl-histidine modification (GO:0018202)2.90128872
136DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.88293402
137protein K11-linked deubiquitination (GO:0035871)2.88149595
138centriole replication (GO:0007099)2.86767504
139ncRNA metabolic process (GO:0034660)2.85880835
140UTP biosynthetic process (GO:0006228)2.85844980
141histone mRNA metabolic process (GO:0008334)2.85032754
142G1/S transition of mitotic cell cycle (GO:0000082)2.84295845
143cell cycle G1/S phase transition (GO:0044843)2.84295845
144rRNA methylation (GO:0031167)2.83883606
145maturation of 5.8S rRNA (GO:0000460)2.83817738
146behavioral response to nicotine (GO:0035095)2.82640412
147prenylation (GO:0097354)2.79207092
148protein prenylation (GO:0018342)2.79207092
149mitochondrial RNA metabolic process (GO:0000959)2.78423396
150rRNA catabolic process (GO:0016075)2.77635906
151piRNA metabolic process (GO:0034587)2.77286003
152neural tube formation (GO:0001841)2.76340627
153response to pheromone (GO:0019236)2.75750763
154regulation of nuclear cell cycle DNA replication (GO:0033262)2.67099175
155tRNA metabolic process (GO:0006399)2.64330562
156mannosylation (GO:0097502)2.63835865
157preassembly of GPI anchor in ER membrane (GO:0016254)2.56960621
158reciprocal meiotic recombination (GO:0007131)2.53826630
159reciprocal DNA recombination (GO:0035825)2.53826630
160L-methionine biosynthetic process (GO:0071265)2.52251387

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.19589380
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.68928218
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.35871073
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.24017317
5GABP_17652178_ChIP-ChIP_JURKAT_Human4.22385627
6EST1_17652178_ChIP-ChIP_JURKAT_Human4.02261820
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.68820910
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.68587072
9* ETS1_20019798_ChIP-Seq_JURKAT_Human3.57094333
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.30925909
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.30899753
12MYC_19079543_ChIP-ChIP_MESCs_Mouse3.16110106
13MYC_18358816_ChIP-ChIP_MESCs_Mouse3.14535787
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.08586231
15ZNF274_21170338_ChIP-Seq_K562_Hela3.06274160
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.00777405
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.91841378
18MYC_19030024_ChIP-ChIP_MESCs_Mouse2.89703550
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.85371113
20VDR_22108803_ChIP-Seq_LS180_Human2.79123309
21VDR_23849224_ChIP-Seq_CD4+_Human2.75484609
22* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.71890356
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.65504948
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.62783628
25EWS_26573619_Chip-Seq_HEK293_Human2.44686188
26* XRN2_22483619_ChIP-Seq_HELA_Human2.44272681
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.35110566
28DCP1A_22483619_ChIP-Seq_HELA_Human2.35097253
29POU3F2_20337985_ChIP-ChIP_501MEL_Human2.23609440
30E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23467316
31FUS_26573619_Chip-Seq_HEK293_Human2.22781750
32FOXP3_21729870_ChIP-Seq_TREG_Human2.22322004
33FLI1_27457419_Chip-Seq_LIVER_Mouse2.16123040
34NELFA_20434984_ChIP-Seq_ESCs_Mouse2.15848298
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.14455218
36ELK1_19687146_ChIP-ChIP_HELA_Human2.13538531
37TTF2_22483619_ChIP-Seq_HELA_Human2.13305645
38ZFP57_27257070_Chip-Seq_ESCs_Mouse2.06448431
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.99079928
40FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.98095519
41* GABP_19822575_ChIP-Seq_HepG2_Human1.94755190
42THAP11_20581084_ChIP-Seq_MESCs_Mouse1.94370724
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.91060607
44GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.89034536
45IGF1R_20145208_ChIP-Seq_DFB_Human1.85845602
46YY1_21170310_ChIP-Seq_MESCs_Mouse1.85782918
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.84116132
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.76327750
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.76310403
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.75784388
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.74873013
52P300_19829295_ChIP-Seq_ESCs_Human1.74488066
53GBX2_23144817_ChIP-Seq_PC3_Human1.71767136
54POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71735743
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.70828030
56ER_23166858_ChIP-Seq_MCF-7_Human1.70324536
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.66925062
58TAF15_26573619_Chip-Seq_HEK293_Human1.62817192
59ELK1_22589737_ChIP-Seq_MCF10A_Human1.61593478
60CTBP2_25329375_ChIP-Seq_LNCAP_Human1.61525621
61GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.59495962
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.57807872
63RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57284715
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57127830
65NANOG_18555785_ChIP-Seq_MESCs_Mouse1.52125418
66PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.52078794
67MYCN_18555785_ChIP-Seq_MESCs_Mouse1.50373880
68PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50220231
69* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.49888382
70EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.49268327
71CTBP1_25329375_ChIP-Seq_LNCAP_Human1.47216911
72MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.46035432
73* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.45006566
74FOXM1_23109430_ChIP-Seq_U2OS_Human1.44952060
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43574510
76TP53_22573176_ChIP-Seq_HFKS_Human1.43450459
77MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41640815
78SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.40117219
79SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37398371
80TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35610361
81YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34798576
82AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.30338444
83CBP_20019798_ChIP-Seq_JUKART_Human1.29626646
84IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29626646
85* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27768763
86EZH2_27294783_Chip-Seq_NPCs_Mouse1.26980050
87ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.26961406
88POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.24835273
89* SPI1_23547873_ChIP-Seq_NB4_Human1.24802878
90SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24502927
91MYC_18940864_ChIP-ChIP_HL60_Human1.23710878
92AR_21909140_ChIP-Seq_LNCAP_Human1.22793677
93GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.22351260
94ZFX_18555785_ChIP-Seq_MESCs_Mouse1.21740518
95IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.20411077
96NFE2_27457419_Chip-Seq_LIVER_Mouse1.20076512
97E2F1_21310950_ChIP-Seq_MCF-7_Human1.20074669
98BP1_19119308_ChIP-ChIP_Hs578T_Human1.19573273
99FOXA1_27270436_Chip-Seq_PROSTATE_Human1.17348368
100FOXA1_25329375_ChIP-Seq_VCAP_Human1.17348368
101KDM5A_27292631_Chip-Seq_BREAST_Human1.15977658
102NANOG_19829295_ChIP-Seq_ESCs_Human1.15101754
103SOX2_19829295_ChIP-Seq_ESCs_Human1.15101754
104BCAT_22108803_ChIP-Seq_LS180_Human1.12922710
105CIITA_25753668_ChIP-Seq_RAJI_Human1.11962724
106KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10931357
107CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10712774
108PCGF2_27294783_Chip-Seq_NPCs_Mouse1.10227938
109PADI4_21655091_ChIP-ChIP_MCF-7_Human1.08233594
110CRX_20693478_ChIP-Seq_RETINA_Mouse1.08233361
111TCF4_22108803_ChIP-Seq_LS180_Human1.07713107
112AR_20517297_ChIP-Seq_VCAP_Human1.06819451
113MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05252901
114STAT3_23295773_ChIP-Seq_U87_Human1.03190426
115BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.03103995
116EGR1_23403033_ChIP-Seq_LIVER_Mouse1.02595947
117FOXA1_21572438_ChIP-Seq_LNCaP_Human1.02562291
118IRF1_19129219_ChIP-ChIP_H3396_Human1.00940234
119CDX2_22108803_ChIP-Seq_LS180_Human1.00417021
120KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99998673
121* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99686479
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98844445
123SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98808421
124CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98356663
125NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98236583
126PIAS1_25552417_ChIP-Seq_VCAP_Human0.97329965
127SMAD4_21799915_ChIP-Seq_A2780_Human0.96109705
128AR_25329375_ChIP-Seq_VCAP_Human0.95713128
129TCF4_23295773_ChIP-Seq_U87_Human0.95523541
130IRF8_21731497_ChIP-ChIP_J774_Mouse0.95436365
131GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93765914
132HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.93158651
133TFEB_21752829_ChIP-Seq_HELA_Human0.92886984
134BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.92778841
135RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.92336675
136HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92210549
137SALL4_22934838_ChIP-ChIP_CD34+_Human0.91438696
138NCOR_22424771_ChIP-Seq_293T_Human0.91358321
139EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91185969
140* FLI1_21867929_ChIP-Seq_TH2_Mouse0.90172675
141CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.90136833
142SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.89286066
143POU5F1_16153702_ChIP-ChIP_HESCs_Human0.88824974
144KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.88796054
145STAT3_1855785_ChIP-Seq_MESCs_Mouse0.88313996
146* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87549872
147* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87344753
148KLF4_18555785_ChIP-Seq_MESCs_Mouse0.81199101
149STAT4_19710469_ChIP-ChIP_TH1__Mouse0.80881146
150CTCF_18555785_ChIP-Seq_MESCs_Mouse0.77234605
151ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.76300597
152KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.75857879
153POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.75703457
154SRY_22984422_ChIP-ChIP_TESTIS_Rat0.74193642
155OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73190497
156SOX17_20123909_ChIP-Seq_XEN_Mouse0.73083099
157DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.71673697
158SOX2_18692474_ChIP-Seq_MEFs_Mouse0.71539934
159TP63_19390658_ChIP-ChIP_HaCaT_Human0.71149149
160NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.70512608
161SOX2_18555785_ChIP-Seq_MESCs_Mouse0.69505385
162MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.66704832
163SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.64217193
164TCF3_18692474_ChIP-Seq_MEFs_Mouse0.63738485
165RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.63514355

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.13490805
2MP0009379_abnormal_foot_pigmentation3.89823401
3MP0004957_abnormal_blastocyst_morpholog3.89716483
4MP0008057_abnormal_DNA_replication3.32692554
5MP0000569_abnormal_digit_pigmentation3.28017581
6MP0010094_abnormal_chromosome_stability3.17955375
7MP0008058_abnormal_DNA_repair2.97152521
8MP0003111_abnormal_nucleus_morphology2.96465790
9MP0003077_abnormal_cell_cycle2.90753199
10MP0006072_abnormal_retinal_apoptosis2.56369978
11MP0008932_abnormal_embryonic_tissue2.55473344
12MP0003718_maternal_effect2.39396792
13MP0003195_calcinosis2.36689163
14MP0003136_yellow_coat_color2.21379093
15MP0003786_premature_aging2.19589288
16MP0002837_dystrophic_cardiac_calcinosis2.19567529
17MP0002396_abnormal_hematopoietic_system2.19275959
18MP0008007_abnormal_cellular_replicative2.17768843
19MP0004381_abnormal_hair_follicle2.02774535
20MP0005551_abnormal_eye_electrophysiolog2.02643915
21MP0009333_abnormal_splenocyte_physiolog2.02560032
22MP0003646_muscle_fatigue1.97296676
23MP0000427_abnormal_hair_cycle1.95613246
24MP0006292_abnormal_olfactory_placode1.93979376
25MP0003186_abnormal_redox_activity1.93100239
26MP0002132_abnormal_respiratory_system1.92464997
27MP0002736_abnormal_nociception_after1.88564079
28MP0005253_abnormal_eye_physiology1.87633334
29MP0005084_abnormal_gallbladder_morpholo1.85316886
30MP0004142_abnormal_muscle_tone1.78210007
31MP0008872_abnormal_physiological_respon1.77610979
32MP0005671_abnormal_response_to1.77200063
33MP0009785_altered_susceptibility_to1.76315689
34MP0000490_abnormal_crypts_of1.75170822
35MP0002148_abnormal_hypersensitivity_rea1.72381457
36MP0001835_abnormal_antigen_presentation1.71757823
37MP0003763_abnormal_thymus_physiology1.59535065
38MP0005075_abnormal_melanosome_morpholog1.59214831
39MP0001853_heart_inflammation1.53099495
40MP0003315_abnormal_perineum_morphology1.51561017
41MP0002876_abnormal_thyroid_physiology1.50697307
42MP0001968_abnormal_touch/_nociception1.48523492
43MP0002277_abnormal_respiratory_mucosa1.43485897
44MP0003950_abnormal_plasma_membrane1.42429285
45MP0008995_early_reproductive_senescence1.42007886
46MP0005025_abnormal_response_to1.41603717
47MP0005389_reproductive_system_phenotype1.41319990
48MP0005646_abnormal_pituitary_gland1.40619758
49MP0005000_abnormal_immune_tolerance1.39475418
50MP0002163_abnormal_gland_morphology1.37645783
51MP0000372_irregular_coat_pigmentation1.37062101
52MP0008875_abnormal_xenobiotic_pharmacok1.36769187
53MP0000383_abnormal_hair_follicle1.36309550
54MP0002398_abnormal_bone_marrow1.34537846
55MP0001529_abnormal_vocalization1.32826701
56MP0002723_abnormal_immune_serum1.30377055
57MP0001800_abnormal_humoral_immune1.29501684
58MP0002138_abnormal_hepatobiliary_system1.29260739
59MP0001986_abnormal_taste_sensitivity1.29037128
60MP0000350_abnormal_cell_proliferation1.28803654
61MP0001905_abnormal_dopamine_level1.28751033
62MP0002452_abnormal_antigen_presenting1.27550533
63MP0002420_abnormal_adaptive_immunity1.26989182
64MP0001485_abnormal_pinna_reflex1.26463491
65MP0001819_abnormal_immune_cell1.25934511
66MP0002095_abnormal_skin_pigmentation1.24132488
67MP0002722_abnormal_immune_system1.23096368
68MP0001730_embryonic_growth_arrest1.23030976
69MP0003436_decreased_susceptibility_to1.21742041
70MP0000689_abnormal_spleen_morphology1.21474568
71MP0008260_abnormal_autophagy1.21196868
72MP0000685_abnormal_immune_system1.19004927
73MP0003806_abnormal_nucleotide_metabolis1.18974552
74MP0000631_abnormal_neuroendocrine_gland1.17197734
75MP0000313_abnormal_cell_death1.16956480
76MP0000716_abnormal_immune_system1.16328192
77MP0002019_abnormal_tumor_incidence1.15290656
78MP0002429_abnormal_blood_cell1.14836680
79MP0005174_abnormal_tail_pigmentation1.14151836
80MP0005310_abnormal_salivary_gland1.13748384
81MP0002102_abnormal_ear_morphology1.12424534
82MP0001919_abnormal_reproductive_system1.11714060
83MP0003252_abnormal_bile_duct1.11235204
84MP0005451_abnormal_body_composition1.08519408
85MP0002638_abnormal_pupillary_reflex1.08327649
86MP0001501_abnormal_sleep_pattern1.07628490
87MP0000703_abnormal_thymus_morphology1.07052169
88MP0004043_abnormal_pH_regulation1.05418947
89MP0000015_abnormal_ear_pigmentation1.05072207
90MP0000858_altered_metastatic_potential1.04850322
91MP0010386_abnormal_urinary_bladder1.04761087
92MP0002405_respiratory_system_inflammati1.04727427
93MP0009046_muscle_twitch1.04606420
94MP0001188_hyperpigmentation1.04325479
95MP0001984_abnormal_olfaction1.02925175
96MP0003724_increased_susceptibility_to1.02388965
97MP0005645_abnormal_hypothalamus_physiol1.02211423
98MP0006036_abnormal_mitochondrial_physio1.02210868
99MP0005397_hematopoietic_system_phenotyp1.01873203
100MP0001545_abnormal_hematopoietic_system1.01873203
101MP0002419_abnormal_innate_immunity1.00682610
102MP0001764_abnormal_homeostasis1.00606630
103MP0004215_abnormal_myocardial_fiber1.00286727
104MP0000647_abnormal_sebaceous_gland0.99851134
105MP0002928_abnormal_bile_duct0.99392396
106MP0005409_darkened_coat_color0.98129613
107MP0001929_abnormal_gametogenesis0.97593400
108MP0005410_abnormal_fertilization0.96615799
109MP0004808_abnormal_hematopoietic_stem0.95771143
110MP0004885_abnormal_endolymph0.94395916
111MP0009745_abnormal_behavioral_response0.94324129
112MP0005266_abnormal_metabolism0.93606258
113MP0002254_reproductive_system_inflammat0.93485793
114MP0000371_diluted_coat_color0.91857783
115MP0001542_abnormal_bone_strength0.91049939
116MP0005408_hypopigmentation0.89806071
117MP0002938_white_spotting0.88250525
118MP0008877_abnormal_DNA_methylation0.86536365
119MP0000465_gastrointestinal_hemorrhage0.86047359
120MP0002693_abnormal_pancreas_physiology0.85377675
121MP0006035_abnormal_mitochondrial_morpho0.85321328
122MP0000653_abnormal_sex_gland0.84662344
123MP0003567_abnormal_fetal_cardiomyocyte0.84326069
124MP0001324_abnormal_eye_pigmentation0.84073375
125MP0002090_abnormal_vision0.83629542
126MP0001790_abnormal_immune_system0.83621560
127MP0005387_immune_system_phenotype0.83621560
128MP0003011_delayed_dark_adaptation0.83315073
129MP0002210_abnormal_sex_determination0.83181735
130MP0001727_abnormal_embryo_implantation0.82420305
131MP0009697_abnormal_copulation0.82267567
132MP0002080_prenatal_lethality0.80678790
133MP0005195_abnormal_posterior_eye0.80548425
134MP0010678_abnormal_skin_adnexa0.80396926
135MP0005379_endocrine/exocrine_gland_phen0.80148104
136MP0001119_abnormal_female_reproductive0.78860615
137MP0002751_abnormal_autonomic_nervous0.78845244
138MP0006082_CNS_inflammation0.78759965
139MP0003941_abnormal_skin_development0.77785684
140MP0001697_abnormal_embryo_size0.77441637
141MP0009764_decreased_sensitivity_to0.77271033
142MP0004147_increased_porphyrin_level0.75394157
143MP0010155_abnormal_intestine_physiology0.74526954
144MP0001145_abnormal_male_reproductive0.73220486
145MP0003698_abnormal_male_reproductive0.72693953
146MP0001293_anophthalmia0.72149466
147MP0003937_abnormal_limbs/digits/tail_de0.71250222
148MP0003938_abnormal_ear_development0.70788770
149MP0005395_other_phenotype0.70355540
150MP0001845_abnormal_inflammatory_respons0.70023107
151MP0005647_abnormal_sex_gland0.69655870
152MP0005501_abnormal_skin_physiology0.68950649
153MP0000358_abnormal_cell_content/0.68883534
154MP0003123_paternal_imprinting0.67912011
155MP0003787_abnormal_imprinting0.67269112
156MP0002006_tumorigenesis0.66884769
157MP0005391_vision/eye_phenotype0.66117314
158MP0008789_abnormal_olfactory_epithelium0.65563290
159MP0006054_spinal_hemorrhage0.65411091
160MP0002160_abnormal_reproductive_system0.65057248
161MP0000613_abnormal_salivary_gland0.65050028

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.38283622
2Abnormal number of erythroid precursors (HP:0012131)5.81808510
3Reticulocytopenia (HP:0001896)5.55804827
4Macrocytic anemia (HP:0001972)4.69115149
5Pancreatic cysts (HP:0001737)4.50554883
6Pallor (HP:0000980)4.25526535
7Increased hepatocellular lipid droplets (HP:0006565)4.05075617
8Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.78237625
9Mitochondrial inheritance (HP:0001427)3.76562168
10Acute necrotizing encephalopathy (HP:0006965)3.69383633
11True hermaphroditism (HP:0010459)3.64991913
12Birth length less than 3rd percentile (HP:0003561)3.64811997
13Pancreatic fibrosis (HP:0100732)3.64303572
143-Methylglutaconic aciduria (HP:0003535)3.63611005
15Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.51676959
16Abnormality of midbrain morphology (HP:0002418)3.44103310
17Molar tooth sign on MRI (HP:0002419)3.44103310
18Lipid accumulation in hepatocytes (HP:0006561)3.39095508
19Increased CSF lactate (HP:0002490)3.29846353
20Hepatocellular necrosis (HP:0001404)3.28961285
21Aplastic anemia (HP:0001915)3.27890423
22Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.25968212
23Decreased activity of mitochondrial respiratory chain (HP:0008972)3.25968212
24Breast hypoplasia (HP:0003187)3.25525741
25Cerebral hypomyelination (HP:0006808)3.24852050
26Abnormal mitochondria in muscle tissue (HP:0008316)3.18021615
27Congenital stationary night blindness (HP:0007642)3.15517555
28Renal Fanconi syndrome (HP:0001994)3.15201172
29Rough bone trabeculation (HP:0100670)3.13689931
30Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.12012145
31Exertional dyspnea (HP:0002875)3.12002820
32Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.99608347
33Abnormality of alanine metabolism (HP:0010916)2.99608347
34Hyperalaninemia (HP:0003348)2.99608347
35Aplasia/Hypoplasia of the sacrum (HP:0008517)2.99460514
36Nephronophthisis (HP:0000090)2.98957077
37Parakeratosis (HP:0001036)2.87296426
38Increased serum lactate (HP:0002151)2.85979260
39Progressive macrocephaly (HP:0004481)2.82989771
40Abnormality of the renal cortex (HP:0011035)2.79743453
41Hepatic necrosis (HP:0002605)2.79369133
42Acute encephalopathy (HP:0006846)2.77839789
43Type I transferrin isoform profile (HP:0003642)2.75953992
44Oral leukoplakia (HP:0002745)2.75835371
45Attenuation of retinal blood vessels (HP:0007843)2.64866856
46Abnormality of the renal medulla (HP:0100957)2.61551744
47Respiratory difficulties (HP:0002880)2.58523045
48Abnormal hemoglobin (HP:0011902)2.58336579
49Congenital, generalized hypertrichosis (HP:0004540)2.55369241
50Medial flaring of the eyebrow (HP:0010747)2.54288474
51Increased intramyocellular lipid droplets (HP:0012240)2.53735068
52Abnormal trabecular bone morphology (HP:0100671)2.53513171
53Microvesicular hepatic steatosis (HP:0001414)2.53030618
54Methylmalonic acidemia (HP:0002912)2.47140125
55Carpal bone hypoplasia (HP:0001498)2.46696056
56Sparse eyelashes (HP:0000653)2.46612204
57Abolished electroretinogram (ERG) (HP:0000550)2.45406649
58Renal cortical cysts (HP:0000803)2.44045147
59Abnormality of the pons (HP:0007361)2.43847289
60Type II lissencephaly (HP:0007260)2.41703056
61Aplasia/Hypoplasia of the uvula (HP:0010293)2.38889806
62Cleft eyelid (HP:0000625)2.38721511
63Pendular nystagmus (HP:0012043)2.38687673
64Hypoplasia of the pons (HP:0012110)2.37396705
65Trismus (HP:0000211)2.34107337
66Large for gestational age (HP:0001520)2.33713303
67Multiple enchondromatosis (HP:0005701)2.33500950
68Congenital ichthyosiform erythroderma (HP:0007431)2.33049316
69Premature graying of hair (HP:0002216)2.31012452
70Exercise intolerance (HP:0003546)2.28643450
71Thrombocytosis (HP:0001894)2.28480180
72Sclerocornea (HP:0000647)2.26643261
73Increased serum pyruvate (HP:0003542)2.23968033
74Abnormality of glycolysis (HP:0004366)2.23968033
75Abnormality of the ileum (HP:0001549)2.22064621
76Abnormality of the preputium (HP:0100587)2.21820063
77Abnormality of secondary sexual hair (HP:0009888)2.21405868
78Abnormality of the axillary hair (HP:0100134)2.21405868
79Aplasia/Hypoplasia of the tibia (HP:0005772)2.21394744
80Respiratory failure (HP:0002878)2.19990672
81Pancytopenia (HP:0001876)2.19837227
82Poor head control (HP:0002421)2.19673903
83Absent thumb (HP:0009777)2.18761943
84Methylmalonic aciduria (HP:0012120)2.17394531
85Cystic liver disease (HP:0006706)2.16427591
86Premature ovarian failure (HP:0008209)2.16425292
87Microretrognathia (HP:0000308)2.16247366
88Patellar aplasia (HP:0006443)2.15927674
89Abnormal rod and cone electroretinograms (HP:0008323)2.15389174
90Gaze-evoked nystagmus (HP:0000640)2.14059905
91Cerebral edema (HP:0002181)2.12907572
92Triphalangeal thumb (HP:0001199)2.12558873
93Lactic acidosis (HP:0003128)2.11641735
94Abnormality of chromosome stability (HP:0003220)2.11634599
95Progressive inability to walk (HP:0002505)2.10954103
96Secondary amenorrhea (HP:0000869)2.10301472
97Male pseudohermaphroditism (HP:0000037)2.07570518
98Aplasia/Hypoplasia of the patella (HP:0006498)2.06930317
99Amniotic constriction ring (HP:0009775)2.06669245
100Abnormality of placental membranes (HP:0011409)2.06669245
101Constricted visual fields (HP:0001133)2.06102946
102Aplasia/Hypoplasia of the tongue (HP:0010295)2.05732108
103Furrowed tongue (HP:0000221)2.05645145
104Absent rod-and cone-mediated responses on ERG (HP:0007688)2.02760666
105Inability to walk (HP:0002540)2.02007983
106Decreased electroretinogram (ERG) amplitude (HP:0000654)2.01062964
107Glossoptosis (HP:0000162)1.99758109
108Depressed nasal ridge (HP:0000457)1.99357023
109Petechiae (HP:0000967)1.98491367
110Clubbing of toes (HP:0100760)1.98126554
111IgM deficiency (HP:0002850)1.95836357
112Colon cancer (HP:0003003)1.94425393
113Chronic hepatic failure (HP:0100626)1.93302969
114Chromsome breakage (HP:0040012)1.93277205
115Abnormality of renal resorption (HP:0011038)1.92533267
116Bile duct proliferation (HP:0001408)1.92338307
117Abnormal biliary tract physiology (HP:0012439)1.92338307
118Increased muscle lipid content (HP:0009058)1.91540983
119Muscle fiber atrophy (HP:0100295)1.88398443
120Stenosis of the external auditory canal (HP:0000402)1.88068986
121Asplenia (HP:0001746)1.88065408
122Type 2 muscle fiber atrophy (HP:0003554)1.87809155
123Bone marrow hypocellularity (HP:0005528)1.87297007
124Hypoplasia of the radius (HP:0002984)1.87040013
125Optic disc pallor (HP:0000543)1.86698288
126Sloping forehead (HP:0000340)1.86662952
127Elevated erythrocyte sedimentation rate (HP:0003565)1.85512706
128Small hand (HP:0200055)1.85127532
129CNS hypomyelination (HP:0003429)1.85126141
130CNS demyelination (HP:0007305)1.84750918
131Meckel diverticulum (HP:0002245)1.82930155
132Reduced antithrombin III activity (HP:0001976)1.82533535
133Abnormality of the heme biosynthetic pathway (HP:0010472)1.82489177
134IgG deficiency (HP:0004315)1.81440628
135Degeneration of anterior horn cells (HP:0002398)1.81286608
136Abnormality of the anterior horn cell (HP:0006802)1.81286608
137Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.81157104
138Abnormal protein N-linked glycosylation (HP:0012347)1.81157104
139Abnormal protein glycosylation (HP:0012346)1.81157104
140Abnormal glycosylation (HP:0012345)1.81157104
141Anencephaly (HP:0002323)1.80982962
142Tubular atrophy (HP:0000092)1.80498583
143Irregular epiphyses (HP:0010582)1.80260558
144Horseshoe kidney (HP:0000085)1.79567068
145Lethargy (HP:0001254)1.79354409
146Agnosia (HP:0010524)1.78629324
147Ketoacidosis (HP:0001993)1.77919002
148Cerebellar dysplasia (HP:0007033)1.77847486
149Lymphoma (HP:0002665)1.77660705
150Hyperventilation (HP:0002883)1.77526880
151Congenital primary aphakia (HP:0007707)1.77301205
152Chromosomal breakage induced by crosslinking agents (HP:0003221)1.76890774
153Decreased central vision (HP:0007663)1.76100832
15411 pairs of ribs (HP:0000878)1.75955560
155Hypothermia (HP:0002045)1.75075366
156Cellular immunodeficiency (HP:0005374)1.74930058
157Congenital sensorineural hearing impairment (HP:0008527)1.74808616
158Abnormality of serum amino acid levels (HP:0003112)1.73154764
159Thyroiditis (HP:0100646)1.70393665
160Congenital hepatic fibrosis (HP:0002612)1.70230934
161Gait imbalance (HP:0002141)1.69375902
162Abnormality of the labia minora (HP:0012880)1.68427276
163Clumsiness (HP:0002312)1.64419321
164Nephrogenic diabetes insipidus (HP:0009806)1.63924861

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.47047473
2NME24.90962809
3STK164.06103745
4BUB13.90660512
5EIF2AK13.71280906
6WEE13.56716035
7EIF2AK32.99452623
8PIM22.62364930
9SRPK12.22299450
10VRK12.19313146
11VRK22.11580324
12PBK2.08826249
13TLK12.04078448
14MAP4K22.01688499
15PLK42.00762280
16NME11.95214525
17MST41.84602127
18TESK21.82181882
19WNK31.77740191
20GRK11.77586386
21MKNK11.63275485
22CDC71.62057116
23TRIM281.61858400
24TSSK61.60012727
25TAOK31.56722042
26INSRR1.47852888
27DYRK31.45580233
28IRAK41.42176572
29IRAK31.39889397
30ACVR1B1.39303999
31OXSR11.37662174
32BRSK21.33663563
33RPS6KB21.32898530
34KDR1.24667865
35MKNK21.23089882
36CDK71.21101462
37PLK11.20742581
38EIF2AK21.15623244
39RPS6KA41.14993429
40MAP3K121.12285876
41AURKB1.12085231
42TAF11.09917653
43CDK191.09801062
44BLK1.07777006
45ARAF1.07135024
46ERBB31.04972714
47ZAK1.03840479
48AURKA1.03636382
49TXK1.03109314
50TTK1.02663354
51EPHA21.00828637
52MAPK130.99429312
53PINK10.97562842
54MAP4K10.96009868
55WNK40.95094852
56ABL20.94274783
57IKBKB0.94274439
58DYRK20.93970216
59ADRBK20.89877099
60TEC0.88951813
61BRAF0.88187503
62ADRBK10.87977746
63CDK80.87110704
64MARK30.86753456
65MAPKAPK50.83299667
66RPS6KA50.82539559
67PDK20.81772827
68PLK30.79736296
69ATR0.79609442
70PIM10.78164011
71NEK20.78069094
72LIMK10.77973960
73CSNK2A10.77972435
74STK30.76807804
75NEK10.75695687
76TNIK0.74867772
77CSNK2A20.74711313
78PLK20.73308795
79PAK30.73216595
80MAP3K110.72818295
81STK38L0.69128433
82TGFBR10.67335801
83CHEK20.67008846
84CLK10.66987150
85PAK10.63161524
86PRKCE0.63053855
87BRSK10.63045514
88ILK0.62385543
89CSNK1G30.61638021
90MAP3K80.61301525
91CAMKK20.60540588
92PNCK0.60426106
93KIT0.59914399
94BMPR1B0.59729133
95BCR0.58398416
96NLK0.58143542
97CASK0.57375136
98LRRK20.56960377
99BTK0.55888543
100LYN0.55624983
101CHUK0.55624047
102STK100.54587976
103PIK3CG0.53804140
104CSNK1G20.50944916
105CSNK1A1L0.49592686
106ZAP700.49495913
107PRKCG0.48817319
108SYK0.48642271
109GRK70.48044472
110MAP2K60.47937308
111MAP3K40.47314249
112MUSK0.46995636
113AKT30.46976875
114CSNK1G10.46028236
115STK40.45893186
116BCKDK0.45031263
117CHEK10.44599389
118BMPR20.44575805
119YES10.43813764
120MAPKAPK30.43663519
121PRKCI0.43061195
122CCNB10.42898465
123PIK3CA0.42296667
124PRKCQ0.41255038
125LATS10.40226934
126IRAK20.39045751
127PASK0.38053553
128TRPM70.37581356
129CDK40.37245816
130PAK40.36915381
131TESK10.36719388
132STK390.34593051
133LCK0.34396768
134NUAK10.33706198
135MATK0.32904376
136CSF1R0.32852821
137RAF10.32766036
138CSNK1A10.32083936
139CDK30.31113156
140ATM0.30655617
141MOS0.30555401
142MYLK0.30425939
143IKBKE0.30103767
144PTK2B0.29678022
145CSNK1D0.29663622

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.00280268
2Proteasome_Homo sapiens_hsa030504.51535413
3RNA polymerase_Homo sapiens_hsa030204.13171038
4DNA replication_Homo sapiens_hsa030303.55145188
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.19557546
6Mismatch repair_Homo sapiens_hsa034302.92553562
7Spliceosome_Homo sapiens_hsa030402.79584424
8Pyrimidine metabolism_Homo sapiens_hsa002402.61876535
9Oxidative phosphorylation_Homo sapiens_hsa001902.55321586
10Homologous recombination_Homo sapiens_hsa034402.38933608
11Nucleotide excision repair_Homo sapiens_hsa034202.33231356
12Base excision repair_Homo sapiens_hsa034102.21317483
13Parkinsons disease_Homo sapiens_hsa050122.20887149
14Protein export_Homo sapiens_hsa030602.19455739
15RNA transport_Homo sapiens_hsa030132.14816649
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.11719977
17Basal transcription factors_Homo sapiens_hsa030221.94937147
18Huntingtons disease_Homo sapiens_hsa050161.79133973
19Selenocompound metabolism_Homo sapiens_hsa004501.75300679
20Phototransduction_Homo sapiens_hsa047441.64763087
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59445685
22Fanconi anemia pathway_Homo sapiens_hsa034601.56998625
23RNA degradation_Homo sapiens_hsa030181.56670280
24Non-homologous end-joining_Homo sapiens_hsa034501.55628007
25Propanoate metabolism_Homo sapiens_hsa006401.53360645
26Nitrogen metabolism_Homo sapiens_hsa009101.51804551
27Butanoate metabolism_Homo sapiens_hsa006501.48207214
28Cell cycle_Homo sapiens_hsa041101.45529666
29Alzheimers disease_Homo sapiens_hsa050101.44437300
30Purine metabolism_Homo sapiens_hsa002301.41727225
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.38782135
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.37525961
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36623110
34One carbon pool by folate_Homo sapiens_hsa006701.23739890
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.22137922
36Sulfur metabolism_Homo sapiens_hsa009201.19428546
37Tryptophan metabolism_Homo sapiens_hsa003801.17000206
38Folate biosynthesis_Homo sapiens_hsa007901.14403570
39Maturity onset diabetes of the young_Homo sapiens_hsa049501.14359295
40Epstein-Barr virus infection_Homo sapiens_hsa051691.11836965
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10755355
42p53 signaling pathway_Homo sapiens_hsa041151.10168608
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.07931174
44Caffeine metabolism_Homo sapiens_hsa002321.01523474
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97854581
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.95396451
47Sulfur relay system_Homo sapiens_hsa041220.91010009
48Vitamin B6 metabolism_Homo sapiens_hsa007500.90576200
49Primary immunodeficiency_Homo sapiens_hsa053400.86231281
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.84161601
51Peroxisome_Homo sapiens_hsa041460.83226914
52Arachidonic acid metabolism_Homo sapiens_hsa005900.82593059
53Steroid hormone biosynthesis_Homo sapiens_hsa001400.82063634
54Chemical carcinogenesis_Homo sapiens_hsa052040.81679363
55Glutathione metabolism_Homo sapiens_hsa004800.80704352
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80080419
57Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79310522
58Allograft rejection_Homo sapiens_hsa053300.78486040
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.78481750
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.76967270
61Asthma_Homo sapiens_hsa053100.76686336
62Herpes simplex infection_Homo sapiens_hsa051680.76546988
63Graft-versus-host disease_Homo sapiens_hsa053320.69387467
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.67489089
65Primary bile acid biosynthesis_Homo sapiens_hsa001200.66527030
66mRNA surveillance pathway_Homo sapiens_hsa030150.66298221
67Systemic lupus erythematosus_Homo sapiens_hsa053220.65399613
68Hematopoietic cell lineage_Homo sapiens_hsa046400.64942621
69Linoleic acid metabolism_Homo sapiens_hsa005910.63823787
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63664923
71Antigen processing and presentation_Homo sapiens_hsa046120.62163914
72Pentose phosphate pathway_Homo sapiens_hsa000300.60393007
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60188885
74Intestinal immune network for IgA production_Homo sapiens_hsa046720.59959274
75Retinol metabolism_Homo sapiens_hsa008300.59804625
76NF-kappa B signaling pathway_Homo sapiens_hsa040640.59434471
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58998728
78Taste transduction_Homo sapiens_hsa047420.55528185
79Olfactory transduction_Homo sapiens_hsa047400.54544466
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53589022
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52952869
82Metabolic pathways_Homo sapiens_hsa011000.51950506
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.51147516
84Measles_Homo sapiens_hsa051620.51003751
85Autoimmune thyroid disease_Homo sapiens_hsa053200.50692015
86Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.49901495
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48327310
88Regulation of autophagy_Homo sapiens_hsa041400.47870675
89Ether lipid metabolism_Homo sapiens_hsa005650.46658691
90Sphingolipid metabolism_Homo sapiens_hsa006000.45490035
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.45126050
92Rheumatoid arthritis_Homo sapiens_hsa053230.44002823
93Legionellosis_Homo sapiens_hsa051340.42320557
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.41761013
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41368220
96Circadian rhythm_Homo sapiens_hsa047100.41126484
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.40253665
98Pyruvate metabolism_Homo sapiens_hsa006200.40023709
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39855838
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39809315
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37601120
102Cardiac muscle contraction_Homo sapiens_hsa042600.37562159
103Steroid biosynthesis_Homo sapiens_hsa001000.36890730
104Mineral absorption_Homo sapiens_hsa049780.34969512
105Shigellosis_Homo sapiens_hsa051310.34790840
106Fatty acid elongation_Homo sapiens_hsa000620.34723668
107Cyanoamino acid metabolism_Homo sapiens_hsa004600.33359145
108Viral carcinogenesis_Homo sapiens_hsa052030.32062667
109Nicotine addiction_Homo sapiens_hsa050330.30524178
110Apoptosis_Homo sapiens_hsa042100.30508803
111Other glycan degradation_Homo sapiens_hsa005110.30500356
112Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30310445
113Vitamin digestion and absorption_Homo sapiens_hsa049770.29955309
114Leishmaniasis_Homo sapiens_hsa051400.27767737
115Malaria_Homo sapiens_hsa051440.25456269
116Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20631580
117Transcriptional misregulation in cancer_Homo sapiens_hsa052020.20217481
118Pertussis_Homo sapiens_hsa051330.20118681
119Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.18814988
120HTLV-I infection_Homo sapiens_hsa051660.18809062
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18154036
122Collecting duct acid secretion_Homo sapiens_hsa049660.17289261
123Jak-STAT signaling pathway_Homo sapiens_hsa046300.16301173
124Influenza A_Homo sapiens_hsa051640.16276728
125Arginine and proline metabolism_Homo sapiens_hsa003300.13409986
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.13238331
127Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.12302880
128Phagosome_Homo sapiens_hsa041450.12015760
129N-Glycan biosynthesis_Homo sapiens_hsa005100.11781247
130Thyroid cancer_Homo sapiens_hsa052160.11289323
131Hepatitis B_Homo sapiens_hsa051610.10760865
132Fructose and mannose metabolism_Homo sapiens_hsa000510.10388367
133Type I diabetes mellitus_Homo sapiens_hsa049400.09251677

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