LENG9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)6.26167416
2viral transcription (GO:0019083)5.86851754
3translational termination (GO:0006415)5.57967353
4ribosomal small subunit biogenesis (GO:0042274)5.23480461
5translational elongation (GO:0006414)4.46273625
6ribosomal small subunit assembly (GO:0000028)4.43959019
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.41773445
8cotranslational protein targeting to membrane (GO:0006613)4.39700244
9protein targeting to ER (GO:0045047)4.37377320
10viral life cycle (GO:0019058)4.24232883
11establishment of protein localization to endoplasmic reticulum (GO:0072599)4.16099007
12cellular protein complex disassembly (GO:0043624)4.12041710
13protein localization to endoplasmic reticulum (GO:0070972)4.10547428
14protoporphyrinogen IX biosynthetic process (GO:0006782)4.04289264
15maturation of SSU-rRNA (GO:0030490)3.99529448
16pyrimidine-containing compound transmembrane transport (GO:0072531)3.93138494
17viral protein processing (GO:0019082)3.89458750
18ATP synthesis coupled proton transport (GO:0015986)3.81364334
19energy coupled proton transport, down electrochemical gradient (GO:0015985)3.81364334
20negative regulation of heart rate (GO:0010459)3.77416240
21nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.72392523
22presynaptic membrane assembly (GO:0097105)3.69257342
23epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.68310888
24positive regulation of gastrulation (GO:2000543)3.65701435
25forebrain neuron differentiation (GO:0021879)3.61836777
26protein neddylation (GO:0045116)3.60714068
27mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.56212521
28axon ensheathment in central nervous system (GO:0032291)3.53575475
29central nervous system myelination (GO:0022010)3.53575475
30protoporphyrinogen IX metabolic process (GO:0046501)3.53242252
31neuronal action potential propagation (GO:0019227)3.45976425
32protein complex disassembly (GO:0043241)3.45824855
33cellular response to ATP (GO:0071318)3.43957082
34limb bud formation (GO:0060174)3.38973932
35water-soluble vitamin biosynthetic process (GO:0042364)3.37671511
36regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.37508293
37establishment of protein localization to mitochondrial membrane (GO:0090151)3.36923596
38serotonin metabolic process (GO:0042428)3.32498427
39negative regulation of appetite (GO:0032099)3.30793407
40negative regulation of response to food (GO:0032096)3.30793407
41positive regulation of systemic arterial blood pressure (GO:0003084)3.29542302
42postsynaptic membrane organization (GO:0001941)3.28014151
43mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.27097704
44negative regulation of synaptic transmission, GABAergic (GO:0032229)3.26964461
45translational initiation (GO:0006413)3.26324520
46regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.24361272
47NADH dehydrogenase complex assembly (GO:0010257)3.23944621
48mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.23944621
49mitochondrial respiratory chain complex I assembly (GO:0032981)3.23944621
50macromolecular complex disassembly (GO:0032984)3.23822017
51negative regulation of cAMP-mediated signaling (GO:0043951)3.22947071
52spinal cord motor neuron differentiation (GO:0021522)3.18313907
53somite development (GO:0061053)3.15836348
54pyrimidine nucleobase catabolic process (GO:0006208)3.15472332
55synaptic transmission, cholinergic (GO:0007271)3.13411570
56presynaptic membrane organization (GO:0097090)3.09764531
57negative regulation of execution phase of apoptosis (GO:1900118)3.04735983
58electron transport chain (GO:0022900)3.04647038
59substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.04410316
60substrate-independent telencephalic tangential migration (GO:0021826)3.04410316
61positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.01544255
62regulation of pigment cell differentiation (GO:0050932)3.00803864
63indolalkylamine metabolic process (GO:0006586)2.99498882
64mitochondrial respiratory chain complex assembly (GO:0033108)2.98325908
65regulation of synapse structural plasticity (GO:0051823)2.97231513
66respiratory electron transport chain (GO:0022904)2.96640076
67primary amino compound metabolic process (GO:1901160)2.95398926
68neuron cell-cell adhesion (GO:0007158)2.89977386
69regulation of bile acid biosynthetic process (GO:0070857)2.88377091
70positive regulation of respiratory burst (GO:0060267)2.84445919
71regulation of respiratory system process (GO:0044065)2.83034659
72tongue development (GO:0043586)2.82748186
73hypothalamus development (GO:0021854)2.80603209
74nephron epithelium morphogenesis (GO:0072088)2.79668459
75nephron tubule morphogenesis (GO:0072078)2.79668459
76auditory receptor cell differentiation (GO:0042491)2.78579847
77protein targeting to membrane (GO:0006612)2.78236147
78axoneme assembly (GO:0035082)2.76244369
79negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.74524325
80negative regulation of telomere maintenance (GO:0032205)2.72748360
81positive regulation of oligodendrocyte differentiation (GO:0048714)2.71465581
82retinal ganglion cell axon guidance (GO:0031290)2.71220692
83developmental pigmentation (GO:0048066)2.70131351
84histone H3 deacetylation (GO:0070932)2.68766527
85regulation of microtubule-based movement (GO:0060632)2.68209856
86sphingoid metabolic process (GO:0046519)2.67864576
87endothelium development (GO:0003158)2.66864939
88negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.66663776
89negative regulation of cell killing (GO:0031342)2.66663776
90regulation of respiratory burst (GO:0060263)2.66198234
91snRNA transcription (GO:0009301)2.65589359
92regulation of glycogen (starch) synthase activity (GO:2000465)2.65135755
93ubiquinone biosynthetic process (GO:0006744)2.64655947
94neuronal action potential (GO:0019228)2.62759531
95cellular response to pH (GO:0071467)2.60880751
96cell differentiation in spinal cord (GO:0021515)2.60534276
97nucleobase catabolic process (GO:0046113)2.59464583
98pattern specification involved in kidney development (GO:0061004)2.59140911
99positive regulation of protein homodimerization activity (GO:0090073)2.58640061
100cardiovascular system development (GO:0072358)2.57864954
101positive regulation of T cell apoptotic process (GO:0070234)2.56504010
102chaperone-mediated protein transport (GO:0072321)2.56421860
103respiratory chain complex IV assembly (GO:0008535)2.55922127
104thalamus development (GO:0021794)2.55663478
105peristalsis (GO:0030432)2.55119425
106DNA deamination (GO:0045006)2.54341289
107regulation of action potential (GO:0098900)2.53229203
108ATP biosynthetic process (GO:0006754)2.52896326
109organ growth (GO:0035265)2.51694091
110regulation of timing of cell differentiation (GO:0048505)2.50550330
111parturition (GO:0007567)2.49861267
112regulation of respiratory gaseous exchange (GO:0043576)2.49097049
113hydrogen ion transmembrane transport (GO:1902600)2.49009316
114positive regulation of growth hormone secretion (GO:0060124)2.48446371
115amyloid precursor protein metabolic process (GO:0042982)2.47768033
116ionotropic glutamate receptor signaling pathway (GO:0035235)2.47536081
117purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.47460736
118indole-containing compound metabolic process (GO:0042430)2.46402936
119intraciliary transport (GO:0042073)2.46264493
120detection of light stimulus involved in sensory perception (GO:0050962)2.45009444
121detection of light stimulus involved in visual perception (GO:0050908)2.45009444
122nuclear-transcribed mRNA catabolic process (GO:0000956)2.44839815
123oligosaccharide catabolic process (GO:0009313)2.44702360
124telencephalon development (GO:0021537)2.44323432
125behavioral defense response (GO:0002209)2.43278895
126behavioral fear response (GO:0001662)2.43278895
127ubiquinone metabolic process (GO:0006743)2.42762066
128negative regulation of multicellular organism growth (GO:0040015)2.41914535
129purine nucleoside triphosphate biosynthetic process (GO:0009145)2.41487170
130positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.41003225
131protein polyglutamylation (GO:0018095)2.40756938
132epithelial cilium movement (GO:0003351)2.39986070
133photoreceptor cell development (GO:0042461)2.39967126
134endocrine pancreas development (GO:0031018)2.38810912
135positive regulation of lymphocyte apoptotic process (GO:0070230)2.38759505
136positive regulation of Notch signaling pathway (GO:0045747)2.38473888
137regulation of cilium movement (GO:0003352)2.37271802
138adaptation of signaling pathway (GO:0023058)2.36971004
139neuron fate determination (GO:0048664)2.36673103
140negative regulation of myotube differentiation (GO:0010832)2.36296499
141sequestering of actin monomers (GO:0042989)2.35734947
142cerebral cortex radially oriented cell migration (GO:0021799)2.32922700
143nonmotile primary cilium assembly (GO:0035058)2.31569796
144oligodendrocyte differentiation (GO:0048709)2.31167621
145negative regulation of T cell mediated immunity (GO:0002710)2.30892744
146positive regulation of protein sumoylation (GO:0033235)2.30654136
147positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)2.29970169
148cornea development in camera-type eye (GO:0061303)2.29509615
149forebrain neuron development (GO:0021884)2.29392017
150neuron fate specification (GO:0048665)2.29241044
151photoreceptor cell differentiation (GO:0046530)2.29237551
152eye photoreceptor cell differentiation (GO:0001754)2.29237551
153regulation of development, heterochronic (GO:0040034)2.28722211
154cell morphogenesis involved in neuron differentiation (GO:0048667)2.28421762
155GPI anchor metabolic process (GO:0006505)2.28365335
156positive regulation of toll-like receptor signaling pathway (GO:0034123)2.28145908
157positive regulation of cellular amine metabolic process (GO:0033240)2.28133674
158T cell migration (GO:0072678)2.27662778
159vitamin transmembrane transport (GO:0035461)2.25912262
160negative regulation of protein localization to cell surface (GO:2000009)2.25812351
161regulation of sensory perception (GO:0051931)2.24374811
162regulation of sensory perception of pain (GO:0051930)2.24374811
163cell proliferation in forebrain (GO:0021846)2.23622716
164GPI anchor biosynthetic process (GO:0006506)2.23570508
165negative regulation of activin receptor signaling pathway (GO:0032926)2.22527989
166mannosylation (GO:0097502)2.21311821
167cytochrome complex assembly (GO:0017004)2.18614248
168short-term memory (GO:0007614)2.18496620
169long-chain fatty acid biosynthetic process (GO:0042759)2.16820256
170omega-hydroxylase P450 pathway (GO:0097267)2.15718847
171regulation of appetite (GO:0032098)2.15571980
172regulation of dopamine metabolic process (GO:0042053)2.15290880
173regulation of catecholamine metabolic process (GO:0042069)2.15290880
174superoxide anion generation (GO:0042554)2.14846289
175adult walking behavior (GO:0007628)2.14439004
176negative regulation of nitric oxide biosynthetic process (GO:0045019)2.12778568
177mature B cell differentiation involved in immune response (GO:0002313)2.11722243
178gamma-aminobutyric acid signaling pathway (GO:0007214)2.11372719
179response to cocaine (GO:0042220)2.11190196
180cilium movement (GO:0003341)2.10566845
181heme biosynthetic process (GO:0006783)2.10281975
182synaptic transmission, glutamatergic (GO:0035249)2.10259216
183male sex determination (GO:0030238)2.09315314
184protein complex biogenesis (GO:0070271)2.08551758
185positive regulation of action potential (GO:0045760)2.07810316

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.64066731
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.74610241
3GBX2_23144817_ChIP-Seq_PC3_Human3.66303043
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.82267995
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.60598905
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.52759095
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.50457640
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.43705063
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.37275048
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.33082890
11TAF15_26573619_Chip-Seq_HEK293_Human2.27304585
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.21759136
13EZH2_27294783_Chip-Seq_ESCs_Mouse2.21004212
14* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.20714993
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.16949125
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.15744095
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.14625066
18IKZF1_21737484_ChIP-ChIP_HCT116_Human2.11722586
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.11528361
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.10259630
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09837369
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.99887728
23RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.98500140
24EZH2_18974828_ChIP-Seq_MESCs_Mouse1.97854009
25RNF2_18974828_ChIP-Seq_MESCs_Mouse1.97854009
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.94636256
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.92720181
28* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.86409376
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.83848041
30ZNF274_21170338_ChIP-Seq_K562_Hela1.77120692
31RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73119277
32* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.72747067
33LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.71754192
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68198645
35P68_20966046_ChIP-Seq_HELA_Human1.67922094
36TP53_20018659_ChIP-ChIP_R1E_Mouse1.66543265
37* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.65417742
38TP63_19390658_ChIP-ChIP_HaCaT_Human1.64144436
39PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.63748333
40E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.56537486
41ERA_21632823_ChIP-Seq_H3396_Human1.52137152
42RNF2_27304074_Chip-Seq_NSC_Mouse1.50828418
43E2F1_20622854_ChIP-Seq_HELA_Human1.50592458
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49512218
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47112362
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.46258104
47RNF2_27304074_Chip-Seq_ESCs_Mouse1.43791901
48BCL6_27268052_Chip-Seq_Bcells_Human1.43718007
49SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.41454109
50VDR_22108803_ChIP-Seq_LS180_Human1.41377919
51EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.40977520
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.39704096
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.38556229
54VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36598434
55REST_21632747_ChIP-Seq_MESCs_Mouse1.35385618
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35044795
57IRF8_22096565_ChIP-ChIP_GC-B_Human1.33394044
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31354920
59PCGF2_27294783_Chip-Seq_ESCs_Mouse1.29814391
60PHF8_20622854_ChIP-Seq_HELA_Human1.29320206
61* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.29031608
62YY1_22570637_ChIP-Seq_MALME-3M_Human1.28169269
63* VDR_21846776_ChIP-Seq_THP-1_Human1.27258910
64TAF2_19829295_ChIP-Seq_ESCs_Human1.26520739
65LXR_22292898_ChIP-Seq_THP-1_Human1.24977245
66* CTCF_20526341_ChIP-Seq_ESCs_Human1.24705657
67SA1_27219007_Chip-Seq_Bcells_Human1.23910807
68MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.21212175
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.20774099
70NANOG_20526341_ChIP-Seq_ESCs_Human1.19819423
71FOXP1_21924763_ChIP-Seq_HESCs_Human1.18992522
72SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.18628720
73CTBP1_25329375_ChIP-Seq_LNCAP_Human1.18436385
74EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17766326
75CDX2_20551321_ChIP-Seq_CACO-2_Human1.17545176
76TET1_21451524_ChIP-Seq_MESCs_Mouse1.17349564
77EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.17008443
78BCOR_27268052_Chip-Seq_Bcells_Human1.15520862
79MYC_19829295_ChIP-Seq_ESCs_Human1.12993087
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.12335364
81SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11835968
82OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.11699550
83DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.11637646
84TP53_22573176_ChIP-Seq_HFKS_Human1.11535688
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.11318414
86ETS1_20019798_ChIP-Seq_JURKAT_Human1.10878867
87IGF1R_20145208_ChIP-Seq_DFB_Human1.10333480
88GABP_17652178_ChIP-ChIP_JURKAT_Human1.09977497
89NOTCH1_21737748_ChIP-Seq_TLL_Human1.09919704
90SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.09873628
91P300_19829295_ChIP-Seq_ESCs_Human1.09691213
92OCT4_19829295_ChIP-Seq_ESCs_Human1.08930217
93NANOG_18555785_Chip-Seq_ESCs_Mouse1.08896029
94RAC3_21632823_ChIP-Seq_H3396_Human1.08190844
95GATA3_21878914_ChIP-Seq_MCF-7_Human1.08007499
96CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07530908
97P53_22387025_ChIP-Seq_ESCs_Mouse1.06879939
98STAT3_18555785_Chip-Seq_ESCs_Mouse1.05983981
99P300_18555785_Chip-Seq_ESCs_Mouse1.05477592
100NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.05174117
101RING1B_27294783_Chip-Seq_ESCs_Mouse1.04793256
102DROSHA_22980978_ChIP-Seq_HELA_Human1.04635050
103PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.03911257
104RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03810245
105OCT4_20526341_ChIP-Seq_ESCs_Human1.03058027
106* CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.02761357
107TAL1_26923725_Chip-Seq_HPCs_Mouse1.02582489
108SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02196456
109RUNX1_27457419_Chip-Seq_LIVER_Mouse1.01566012
110ETV2_25802403_ChIP-Seq_MESCs_Mouse1.00486116
111ZFX_18555785_Chip-Seq_ESCs_Mouse0.99745275
112GATA1_26923725_Chip-Seq_HPCs_Mouse0.99596463
113NMYC_18555785_Chip-Seq_ESCs_Mouse0.99207762
114CMYC_18555785_Chip-Seq_ESCs_Mouse0.98925288
115TDRD3_21172665_ChIP-Seq_MCF-7_Human0.98840682
116SA1_27219007_Chip-Seq_ERYTHROID_Human0.98631928
117EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98460238
118PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98392181
119EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.98221294
120JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.98160808
121MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97883303
122NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97671276
123* CTCF_27219007_Chip-Seq_Bcells_Human0.97425648
124SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97405652
125SMAD3_21741376_ChIP-Seq_EPCs_Human0.96821293
126P300_27268052_Chip-Seq_Bcells_Human0.96302737
127WT1_19549856_ChIP-ChIP_CCG9911_Human0.95442671
128POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95262643
129AR_21572438_ChIP-Seq_LNCaP_Human0.95036112
130CTBP2_25329375_ChIP-Seq_LNCAP_Human0.94984892
131MYC_18940864_ChIP-ChIP_HL60_Human0.94798793
132SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94380324
133P53_21459846_ChIP-Seq_SAOS-2_Human0.93728769
134WDR5_24793694_ChIP-Seq_LNCAP_Human0.93494821
135TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92446224
136* XRN2_22483619_ChIP-Seq_HELA_Human0.92281330
137SMC4_20622854_ChIP-Seq_HELA_Human0.92176391
138SMAD_19615063_ChIP-ChIP_OVARY_Human0.91382256
139GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.91346450
140OCT4_18555785_Chip-Seq_ESCs_Mouse0.91314428
141SOX2_18555785_Chip-Seq_ESCs_Mouse0.91304551
142TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90843588
143RING1B_27294783_Chip-Seq_NPCs_Mouse0.90318618
144STAT1_20625510_ChIP-Seq_HELA_Human0.89374413
145ER_23166858_ChIP-Seq_MCF-7_Human0.89161226
146IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.88894917
147EZH2_27294783_Chip-Seq_NPCs_Mouse0.88275430
148P53_22127205_ChIP-Seq_FIBROBLAST_Human0.88075257
149E2F1_18555785_Chip-Seq_ESCs_Mouse0.86443723
150IRF1_19129219_ChIP-ChIP_H3396_Human0.86193201
151KDM2B_26808549_Chip-Seq_REH_Human0.85433224
152SMAD4_21799915_ChIP-Seq_A2780_Human0.84963268
153EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84955108
154PU1_27457419_Chip-Seq_LIVER_Mouse0.83422835
155SMAD1_18555785_Chip-Seq_ESCs_Mouse0.81701862
156ERG_21242973_ChIP-ChIP_JURKAT_Human0.80748032
157SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.80608046
158* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.80364401
159STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.80231871
160ESRRB_18555785_Chip-Seq_ESCs_Mouse0.80051904
161REST_18959480_ChIP-ChIP_MESCs_Mouse0.79784577
162OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.78921870
163CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.78819522

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.79481474
2MP0009379_abnormal_foot_pigmentation3.77764692
3MP0003724_increased_susceptibility_to3.07319411
4MP0002653_abnormal_ependyma_morphology2.79339137
5MP0005409_darkened_coat_color2.60610286
6MP0000566_synostosis2.56753227
7MP0003880_abnormal_central_pattern2.41206365
8MP0001188_hyperpigmentation2.34336197
9MP0006276_abnormal_autonomic_nervous2.27496603
10MP0002009_preneoplasia2.10253281
11MP0003123_paternal_imprinting2.04011464
12MP0000778_abnormal_nervous_system2.02324869
13MP0004742_abnormal_vestibular_system1.98089842
14MP0003183_abnormal_peptide_metabolism1.88675612
15MP0004381_abnormal_hair_follicle1.86999056
16MP0002277_abnormal_respiratory_mucosa1.84886748
17MP0002876_abnormal_thyroid_physiology1.82291495
18MP0006072_abnormal_retinal_apoptosis1.81979052
19MP0008789_abnormal_olfactory_epithelium1.78712549
20MP0005084_abnormal_gallbladder_morpholo1.75647970
21MP0005645_abnormal_hypothalamus_physiol1.74839264
22MP0003136_yellow_coat_color1.69819088
23MP0001986_abnormal_taste_sensitivity1.67044088
24MP0002736_abnormal_nociception_after1.63280511
25MP0001664_abnormal_digestion1.60871137
26MP0004885_abnormal_endolymph1.60249718
27MP0005310_abnormal_salivary_gland1.57710946
28MP0005174_abnormal_tail_pigmentation1.55619211
29MP0002837_dystrophic_cardiac_calcinosis1.51835698
30MP0002909_abnormal_adrenal_gland1.51093735
31MP0003878_abnormal_ear_physiology1.50346813
32MP0005377_hearing/vestibular/ear_phenot1.50346813
33MP0002693_abnormal_pancreas_physiology1.46803349
34MP0005499_abnormal_olfactory_system1.46317478
35MP0005394_taste/olfaction_phenotype1.46317478
36MP0002272_abnormal_nervous_system1.44734913
37MP0005646_abnormal_pituitary_gland1.44088607
38MP0001905_abnormal_dopamine_level1.42198888
39MP0000015_abnormal_ear_pigmentation1.40012047
40MP0002928_abnormal_bile_duct1.38041816
41MP0005670_abnormal_white_adipose1.36345600
42MP0009745_abnormal_behavioral_response1.35736019
43MP0002735_abnormal_chemical_nociception1.34502800
44MP0001873_stomach_inflammation1.34448861
45MP0003763_abnormal_thymus_physiology1.34082280
46MP0001663_abnormal_digestive_system1.33464858
47MP0001486_abnormal_startle_reflex1.33359200
48MP0004142_abnormal_muscle_tone1.33318441
49MP0002138_abnormal_hepatobiliary_system1.32537640
50MP0005423_abnormal_somatic_nervous1.31273097
51MP0003866_abnormal_defecation1.30386283
52MP0004270_analgesia1.30324015
53MP0010030_abnormal_orbit_morphology1.29137683
54MP0002064_seizures1.28197051
55MP0003121_genomic_imprinting1.27216472
56MP0005551_abnormal_eye_electrophysiolog1.26937998
57MP0002822_catalepsy1.26755599
58MP0001485_abnormal_pinna_reflex1.25655976
59MP0009046_muscle_twitch1.24339120
60MP0002572_abnormal_emotion/affect_behav1.24074860
61MP0003122_maternal_imprinting1.22590659
62MP0001944_abnormal_pancreas_morphology1.21588359
63MP0004133_heterotaxia1.21383980
64MP0005387_immune_system_phenotype1.19879209
65MP0001790_abnormal_immune_system1.19879209
66MP0002938_white_spotting1.18910088
67MP0005671_abnormal_response_to1.16790775
68MP0005381_digestive/alimentary_phenotyp1.15630691
69MP0000955_abnormal_spinal_cord1.15312880
70MP0002063_abnormal_learning/memory/cond1.14600930
71MP0000678_abnormal_parathyroid_gland1.13712458
72MP0001502_abnormal_circadian_rhythm1.13702684
73MP0002933_joint_inflammation1.12360153
74MP0002160_abnormal_reproductive_system1.12092545
75MP0005195_abnormal_posterior_eye1.11541157
76MP0005379_endocrine/exocrine_gland_phen1.09519122
77MP0003283_abnormal_digestive_organ1.08518423
78MP0009785_altered_susceptibility_to1.08079826
79MP0003195_calcinosis1.07995764
80MP0002184_abnormal_innervation1.06308586
81MP0002557_abnormal_social/conspecific_i1.06298163
82MP0004043_abnormal_pH_regulation1.05811768
83MP0002752_abnormal_somatic_nervous1.04764361
84MP0001919_abnormal_reproductive_system1.04466960
85MP0003938_abnormal_ear_development1.04290137
86MP0005000_abnormal_immune_tolerance1.04246000
87MP0009697_abnormal_copulation1.04110198
88MP0001756_abnormal_urination1.03834548
89MP0000613_abnormal_salivary_gland1.03825304
90MP0005389_reproductive_system_phenotype1.02149087
91MP0002102_abnormal_ear_morphology1.02016547
92MP0000049_abnormal_middle_ear1.00938736
93MP0002723_abnormal_immune_serum0.99283376
94MP0003011_delayed_dark_adaptation0.99143408
95MP0002148_abnormal_hypersensitivity_rea0.98490841
96MP0002067_abnormal_sensory_capabilities0.98026538
97MP0001501_abnormal_sleep_pattern0.97804253
98MP0003787_abnormal_imprinting0.96755269
99MP0001984_abnormal_olfaction0.95991790
100MP0001835_abnormal_antigen_presentation0.95937551
101MP0009840_abnormal_foam_cell0.95561831
102MP0001440_abnormal_grooming_behavior0.95520878
103MP0001970_abnormal_pain_threshold0.94528974
104MP0002882_abnormal_neuron_morphology0.94320165
105MP0001293_anophthalmia0.91970944
106MP0005253_abnormal_eye_physiology0.91321374
107MP0008877_abnormal_DNA_methylation0.90296464
108MP0000026_abnormal_inner_ear0.90174102
109MP0008872_abnormal_physiological_respon0.89657900
110MP0009764_decreased_sensitivity_to0.89489669
111MP0003635_abnormal_synaptic_transmissio0.88676197
112MP0003868_abnormal_feces_composition0.87986737
113MP0003879_abnormal_hair_cell0.87174270
114MP0004510_myositis0.86742534
115MP0002163_abnormal_gland_morphology0.86004684
116MP0001324_abnormal_eye_pigmentation0.85790555
117MP0001666_abnormal_nutrient_absorption0.85456092
118MP0002734_abnormal_mechanical_nocicepti0.85409605
119MP0001800_abnormal_humoral_immune0.85359127
120MP0000631_abnormal_neuroendocrine_gland0.85046884
121MP0003303_peritoneal_inflammation0.84262611
122MP0001765_abnormal_ion_homeostasis0.84224928
123MP0010386_abnormal_urinary_bladder0.83794761
124MP0002638_abnormal_pupillary_reflex0.83413176
125MP0005386_behavior/neurological_phenoty0.83053991
126MP0004924_abnormal_behavior0.83053991
127MP0002095_abnormal_skin_pigmentation0.82586398
128MP0000230_abnormal_systemic_arterial0.82448819
129MP0010155_abnormal_intestine_physiology0.80743137
130MP0004019_abnormal_vitamin_homeostasis0.80481749
131MP0008875_abnormal_xenobiotic_pharmacok0.80171368
132MP0002733_abnormal_thermal_nociception0.79990456
133MP0001963_abnormal_hearing_physiology0.79168323
134MP0001529_abnormal_vocalization0.78414841
135MP0005448_abnormal_energy_balance0.78152293
136MP0002452_abnormal_antigen_presenting0.78121618
137MP0001819_abnormal_immune_cell0.77505266
138MP0002152_abnormal_brain_morphology0.77393036
139MP0002420_abnormal_adaptive_immunity0.76521053
140MP0006082_CNS_inflammation0.75900595
141MP0001968_abnormal_touch/_nociception0.75020956
142MP0002419_abnormal_innate_immunity0.74159012
143MP0003950_abnormal_plasma_membrane0.74136554
144MP0005332_abnormal_amino_acid0.72738879
145MP0002210_abnormal_sex_determination0.72634003
146MP0002249_abnormal_larynx_morphology0.72455094
147MP0004130_abnormal_muscle_cell0.69066396

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.07326917
2Abnormality of the heme biosynthetic pathway (HP:0010472)4.01094488
3Rib fusion (HP:0000902)3.95177687
4Reticulocytopenia (HP:0001896)3.90582993
5Cerebral palsy (HP:0100021)3.83107118
6Congenital stationary night blindness (HP:0007642)3.74135923
7Confusion (HP:0001289)3.69118501
8Abnormal number of erythroid precursors (HP:0012131)3.57415774
93-Methylglutaconic aciduria (HP:0003535)3.55378303
10Abnormality of midbrain morphology (HP:0002418)3.49054754
11Molar tooth sign on MRI (HP:0002419)3.49054754
12Pancreatic fibrosis (HP:0100732)3.33130392
13Morphological abnormality of the middle ear (HP:0008609)3.19724227
14Limb dystonia (HP:0002451)3.09213208
15Pancreatic cysts (HP:0001737)3.08986068
16Absent/shortened dynein arms (HP:0200106)3.05495956
17Dynein arm defect of respiratory motile cilia (HP:0012255)3.05495956
18Paralysis (HP:0003470)3.01383577
19Agammaglobulinemia (HP:0004432)2.97807075
20Hypothermia (HP:0002045)2.92188912
21Nephronophthisis (HP:0000090)2.89848432
22Macrocytic anemia (HP:0001972)2.87137508
23Mutism (HP:0002300)2.86572658
24Mitochondrial inheritance (HP:0001427)2.82910277
25Abnormal drinking behavior (HP:0030082)2.82246940
26Polydipsia (HP:0001959)2.82246940
27Hepatocellular necrosis (HP:0001404)2.80214820
28Bony spicule pigmentary retinopathy (HP:0007737)2.80104302
29Abnormal delayed hypersensitivity skin test (HP:0002963)2.79932019
30Tubular atrophy (HP:0000092)2.75668006
31Autoimmune hemolytic anemia (HP:0001890)2.74132434
32Myokymia (HP:0002411)2.70966449
33Abnormal rod and cone electroretinograms (HP:0008323)2.67870518
34Absent thumb (HP:0009777)2.66492476
35Chronic mucocutaneous candidiasis (HP:0002728)2.66464595
36Recurrent cutaneous fungal infections (HP:0011370)2.66464595
37Pallor (HP:0000980)2.61891629
38Flat occiput (HP:0005469)2.60516687
39Congenital sensorineural hearing impairment (HP:0008527)2.59850301
40Panhypogammaglobulinemia (HP:0003139)2.55328276
41Thyroid-stimulating hormone excess (HP:0002925)2.55031204
42Optic disc pallor (HP:0000543)2.53520665
43Pendular nystagmus (HP:0012043)2.51002529
44Absent hand (HP:0004050)2.44697403
45Polyphagia (HP:0002591)2.44048282
46Abnormal respiratory epithelium morphology (HP:0012253)2.42582387
47Abnormal respiratory motile cilium morphology (HP:0005938)2.42582387
48Abnormality of the renal medulla (HP:0100957)2.41803786
49Type II lissencephaly (HP:0007260)2.40527202
50Absent rod-and cone-mediated responses on ERG (HP:0007688)2.40349027
51Patellar aplasia (HP:0006443)2.39311818
52Aplasia/Hypoplasia of the patella (HP:0006498)2.37756833
53Acute necrotizing encephalopathy (HP:0006965)2.36380011
54Medial flaring of the eyebrow (HP:0010747)2.35615959
55Sclerocornea (HP:0000647)2.35131516
56Atelectasis (HP:0100750)2.33982023
57Hyperthyroidism (HP:0000836)2.30769654
58Septo-optic dysplasia (HP:0100842)2.27294598
59Increased muscle lipid content (HP:0009058)2.26776717
60Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.23873258
61Abnormal ciliary motility (HP:0012262)2.23740087
62Hypomagnesemia (HP:0002917)2.23295607
63Hepatic necrosis (HP:0002605)2.23085586
64Abnormality of magnesium homeostasis (HP:0004921)2.22865339
65Decreased circulating renin level (HP:0003351)2.22719254
66Increased intramyocellular lipid droplets (HP:0012240)2.21497192
67Cystic liver disease (HP:0006706)2.21106464
68Metabolic alkalosis (HP:0200114)2.20404497
69Chorioretinal atrophy (HP:0000533)2.19625639
70Abnormality of calcium-phosphate metabolism (HP:0100530)2.19214896
71Abnormality of renal resorption (HP:0011038)2.18489609
72Submucous cleft hard palate (HP:0000176)2.17202188
73Porencephaly (HP:0002132)2.15596512
74Renal Fanconi syndrome (HP:0001994)2.15268486
75Decreased central vision (HP:0007663)2.14288396
76Ileus (HP:0002595)2.13888052
77Acute encephalopathy (HP:0006846)2.12095327
78Bile duct proliferation (HP:0001408)2.11431663
79Abnormal biliary tract physiology (HP:0012439)2.11431663
80Abnormal mitochondria in muscle tissue (HP:0008316)2.09627411
81Anophthalmia (HP:0000528)2.04891794
82Stomatitis (HP:0010280)2.04100535
83Pulmonary fibrosis (HP:0002206)2.01753934
84Aplasia/hypoplasia of the uterus (HP:0008684)2.01347466
85Maternal diabetes (HP:0009800)2.01060636
86Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.00596363
87Hypoplasia of the pons (HP:0012110)2.00461441
88Chronic sinusitis (HP:0011109)2.00327457
89Polyuria (HP:0000103)1.98899595
90Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.98542338
91Anencephaly (HP:0002323)1.98291062
92Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.97487093
93Gait imbalance (HP:0002141)1.97174132
94Hyperglycinemia (HP:0002154)1.97148952
95Abnormality of the pulmonary veins (HP:0011718)1.96837137
96Ketosis (HP:0001946)1.96174864
97Seborrheic dermatitis (HP:0001051)1.94991731
98Abnormality of the pons (HP:0007361)1.94413925
99Increased hepatocellular lipid droplets (HP:0006565)1.92330401
100Split foot (HP:0001839)1.92123038
101Abnormality of urine glucose concentration (HP:0011016)1.92032542
102Glycosuria (HP:0003076)1.92032542
103IgM deficiency (HP:0002850)1.91516382
104Bradycardia (HP:0001662)1.91488148
105Colon cancer (HP:0003003)1.91407398
106Cheilitis (HP:0100825)1.90341704
107Congenital hepatic fibrosis (HP:0002612)1.89918367
108Lissencephaly (HP:0001339)1.89770278
109Aplasia/Hypoplasia of the sacrum (HP:0008517)1.89692260
110Congenital primary aphakia (HP:0007707)1.89553638
111Hypoplasia of the ulna (HP:0003022)1.89237795
112Exertional dyspnea (HP:0002875)1.88083440
113Chronic hepatic failure (HP:0100626)1.86319595
114Recurrent bronchitis (HP:0002837)1.85741022
115Enlarged kidneys (HP:0000105)1.85662182
116Recurrent sinusitis (HP:0011108)1.85155156
117B lymphocytopenia (HP:0010976)1.84645292
118Abnormality of B cell number (HP:0010975)1.84645292
119Progressive macrocephaly (HP:0004481)1.83508204
120Increased CSF lactate (HP:0002490)1.83277319
121Conjugated hyperbilirubinemia (HP:0002908)1.82156623
122Meningitis (HP:0001287)1.78798888
123Abnormality of secondary sexual hair (HP:0009888)1.78570993
124Abnormality of the axillary hair (HP:0100134)1.78570993
125Anomalous pulmonary venous return (HP:0010772)1.78428527
126Nephrogenic diabetes insipidus (HP:0009806)1.78245217
127Hepatoblastoma (HP:0002884)1.78064234
128Abnormal respiratory motile cilium physiology (HP:0012261)1.77936806
129Annular pancreas (HP:0001734)1.77336034
130Type I transferrin isoform profile (HP:0003642)1.77271422
131Hyperinsulinemic hypoglycemia (HP:0000825)1.77160953
132Male pseudohermaphroditism (HP:0000037)1.76866486
133Inflammation of the large intestine (HP:0002037)1.76824866
134Abnormality of the renal cortex (HP:0011035)1.76367573
135Abnormal pupillary function (HP:0007686)1.76342384
136Severe muscular hypotonia (HP:0006829)1.75565869
137Hypoplasia of the radius (HP:0002984)1.75325366
138Onycholysis (HP:0001806)1.74865318
139Abnormality of the nasal septum (HP:0000419)1.74734674
140Abnormal urine phosphate concentration (HP:0012599)1.73929493
141Hyperphosphaturia (HP:0003109)1.73594752
142Optic nerve coloboma (HP:0000588)1.73214850
143Concave nail (HP:0001598)1.72999271
144Abnormality of renin-angiotensin system (HP:0000847)1.72734924
145Joint hemorrhage (HP:0005261)1.71716742
146True hermaphroditism (HP:0010459)1.70798628
147Lactic acidosis (HP:0003128)1.70465899
148Abnormality of DNA repair (HP:0003254)1.69608458
149Symptomatic seizures (HP:0011145)1.69510414
150Hepatosplenomegaly (HP:0001433)1.69295708
151Skin rash (HP:0000988)1.69161282
152Mesangial abnormality (HP:0001966)1.68900543
153Attenuation of retinal blood vessels (HP:0007843)1.68663777
154Brushfield spots (HP:0001088)1.68409026
155Abnormal urine output (HP:0012590)1.67939124
156Inability to walk (HP:0002540)1.67556164
157Decreased electroretinogram (ERG) amplitude (HP:0000654)1.67504954
158Lipid accumulation in hepatocytes (HP:0006561)1.66590486
159Lip pit (HP:0100267)1.66041015
160Colitis (HP:0002583)1.66034800
161Respiratory difficulties (HP:0002880)1.65227243
162Prolonged QT interval (HP:0001657)1.64958733
163Hyperkalemia (HP:0002153)1.64702293
164Agitation (HP:0000713)1.64639031
165Chronic obstructive pulmonary disease (HP:0006510)1.64598320
166Obstructive lung disease (HP:0006536)1.64598320
167Specific learning disability (HP:0001328)1.64212614
168Nonprogressive disorder (HP:0003680)1.64064643
169Encephalitis (HP:0002383)1.64060465

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR6.33842155
2CASK4.25544972
3WNK44.17228560
4IRAK33.32640495
5MAP2K73.07177405
6TLK12.80391666
7ACVR1B2.65047263
8DYRK22.48663253
9MAPK152.40743049
10CDK192.36398208
11TNIK2.21798938
12BLK2.15885219
13TYRO32.15868692
14STK162.13307408
15MAP3K112.10262905
16IRAK12.09094850
17PINK12.04699011
18MAP3K62.00677377
19PRKD21.97543172
20FRK1.89282648
21MAP3K41.82487600
22MKNK21.76823347
23IRAK41.71857908
24PKN11.65398679
25MARK11.64116017
26IRAK21.56055282
27EPHB21.56029222
28NTRK21.54120404
29NLK1.52544937
30MAP3K121.51093293
31PNCK1.38438613
32MUSK1.33789071
33DAPK21.31910653
34BMPR1B1.30175258
35PRKCG1.29255346
36FES1.27851363
37STK111.25066007
38MAPKAPK51.17752715
39TXK1.15930844
40MAP2K21.11106211
41VRK11.10257323
42NME11.06939985
43ADRBK11.03186818
44MAPK131.02780241
45ADRBK20.99538708
46IKBKE0.99450025
47PRPF4B0.97847603
48KIT0.95715954
49TAOK30.93850696
50TEC0.93002403
51PAK30.91982497
52PRKCH0.91793068
53MARK20.91322174
54BCKDK0.91047895
55CLK10.90957328
56CDK30.90754231
57PIK3CA0.89629938
58OXSR10.87060363
59MAP2K60.85651780
60WNK30.85146648
61MINK10.84025827
62SRPK10.81207551
63MAP3K140.80473892
64BTK0.80055962
65MAP2K40.79982439
66PRKCZ0.79084540
67PRKCQ0.78526063
68ITK0.77525329
69TAF10.77385696
70RPS6KA60.76205141
71CAMK1D0.76196421
72CAMK2B0.75108436
73CHUK0.75007420
74IKBKB0.74837763
75MYLK0.74234250
76MAP3K20.73651015
77TGFBR10.72498964
78VRK20.72251535
79MAP4K10.71904249
80NEK60.71725606
81PRKAA20.71477813
82HIPK20.70498040
83PRKACA0.69700230
84BMPR20.69497792
85TNK20.67802375
86SGK2230.66123287
87SGK4940.66123287
88GRK70.65703498
89RPS6KA50.65436656
90RPS6KA20.65370756
91DYRK30.64932126
92AURKA0.64458233
93NUAK10.64269494
94EPHA30.63640380
95YES10.63327403
96TBK10.63144269
97CSNK1G20.62083258
98MAP4K20.61480316
99GRK10.60612184
100NTRK30.60397656
101TIE10.59593656
102DYRK1B0.59110650
103ABL20.59059579
104TRIM280.58888495
105EPHB10.56475626
106CAMK1G0.56327215
107PBK0.55912557
108DYRK1A0.55796319
109JAK30.55762113
110CAMK10.55479237
111NME20.55407759
112SIK20.54826890
113FGR0.53970492
114CSNK1E0.53053279
115PIM20.52867161
116MAPK70.50039914
117PRKCE0.49885552
118SGK10.49466286
119CAMK2D0.48468870
120MKNK10.47856523
121RPS6KC10.47667751
122RPS6KL10.47667751
123CDK80.47407213
124STK390.47384678
125CAMKK20.46555428
126PHKG20.45946996
127PHKG10.45946996
128CAMKK10.45282677
129LRRK20.45128593
130BRD40.44736745
131CSK0.44664701
132CDC42BPA0.44045151
133MAPK40.43766184
134LCK0.43379519
135DAPK30.43086350
136MAP3K70.43004201
137CDK50.42276133
138PRKG20.42241539
139NEK20.42156844
140BRAF0.42124697
141LYN0.41666315
142PRKCD0.40995746
143SYK0.39824336
144PRKCA0.39152893
145CSNK1G10.37269824
146CAMK2G0.35961070
147CAMK2A0.34334048
148CDK90.33517269
149PRKCI0.33445691
150PDK20.32889256
151GRK60.31451868
152CSNK1A10.31202286
153MAPK110.30664083
154CSNK1G30.28826425
155ZAK0.28510266

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041223.67376663
2Oxidative phosphorylation_Homo sapiens_hsa001903.06978383
3Maturity onset diabetes of the young_Homo sapiens_hsa049503.03839646
4Protein export_Homo sapiens_hsa030602.87997162
5Vitamin digestion and absorption_Homo sapiens_hsa049772.74436418
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.21744256
7Sphingolipid metabolism_Homo sapiens_hsa006002.15768235
8Parkinsons disease_Homo sapiens_hsa050122.04833942
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.96274352
10Nicotine addiction_Homo sapiens_hsa050331.94777353
11Alzheimers disease_Homo sapiens_hsa050101.92640735
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.92630547
13Primary immunodeficiency_Homo sapiens_hsa053401.88540935
14Ether lipid metabolism_Homo sapiens_hsa005651.85224427
15Ribosome_Homo sapiens_hsa030101.59426078
16Caffeine metabolism_Homo sapiens_hsa002321.56849344
17Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.56369430
18Phototransduction_Homo sapiens_hsa047441.55656773
19Linoleic acid metabolism_Homo sapiens_hsa005911.54823217
20Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.54810986
21Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.53972923
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.53728351
23Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.52428524
24Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.45626942
25Arachidonic acid metabolism_Homo sapiens_hsa005901.43514933
26Hedgehog signaling pathway_Homo sapiens_hsa043401.42263796
27alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.41065852
28Taste transduction_Homo sapiens_hsa047421.39152204
29Collecting duct acid secretion_Homo sapiens_hsa049661.37358106
30Glutamatergic synapse_Homo sapiens_hsa047241.36863330
31Fatty acid elongation_Homo sapiens_hsa000621.36646360
32Serotonergic synapse_Homo sapiens_hsa047261.35818737
33Basal cell carcinoma_Homo sapiens_hsa052171.33369123
34Huntingtons disease_Homo sapiens_hsa050161.33075720
35Morphine addiction_Homo sapiens_hsa050321.32042561
36Other glycan degradation_Homo sapiens_hsa005111.28312478
37Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.26825985
38Fat digestion and absorption_Homo sapiens_hsa049751.26597412
39GABAergic synapse_Homo sapiens_hsa047271.25685375
40Hematopoietic cell lineage_Homo sapiens_hsa046401.22841886
41Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.19073972
42Vibrio cholerae infection_Homo sapiens_hsa051101.18401972
43Insulin secretion_Homo sapiens_hsa049111.14787199
44Fanconi anemia pathway_Homo sapiens_hsa034601.13210942
45Rheumatoid arthritis_Homo sapiens_hsa053231.11102599
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.10540532
47Cocaine addiction_Homo sapiens_hsa050301.08028566
48Mineral absorption_Homo sapiens_hsa049781.04709835
49Homologous recombination_Homo sapiens_hsa034401.04281613
50Histidine metabolism_Homo sapiens_hsa003401.02688360
51Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.99967031
52Amphetamine addiction_Homo sapiens_hsa050310.99493162
53Nitrogen metabolism_Homo sapiens_hsa009100.98967741
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.96055357
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.91230782
56Folate biosynthesis_Homo sapiens_hsa007900.90812218
57Circadian entrainment_Homo sapiens_hsa047130.90308848
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.89451364
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88345526
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.86876304
61Pancreatic secretion_Homo sapiens_hsa049720.86050259
62Sulfur metabolism_Homo sapiens_hsa009200.85403935
63Peroxisome_Homo sapiens_hsa041460.85153826
64Notch signaling pathway_Homo sapiens_hsa043300.83503516
65Salivary secretion_Homo sapiens_hsa049700.82629394
66Selenocompound metabolism_Homo sapiens_hsa004500.82352671
67Chemical carcinogenesis_Homo sapiens_hsa052040.81987860
68NF-kappa B signaling pathway_Homo sapiens_hsa040640.80948124
69Basal transcription factors_Homo sapiens_hsa030220.80347542
70Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.80115311
71Long-term depression_Homo sapiens_hsa047300.79454895
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79436787
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78153726
74Butanoate metabolism_Homo sapiens_hsa006500.77316758
75Renin secretion_Homo sapiens_hsa049240.76763424
76Arginine and proline metabolism_Homo sapiens_hsa003300.74176309
77Calcium signaling pathway_Homo sapiens_hsa040200.73691451
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.70407872
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.69252404
80RNA polymerase_Homo sapiens_hsa030200.68761781
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68303387
82RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.66828415
83Dopaminergic synapse_Homo sapiens_hsa047280.64443166
84Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.64056707
85African trypanosomiasis_Homo sapiens_hsa051430.63474834
86Graft-versus-host disease_Homo sapiens_hsa053320.62938431
87Dorso-ventral axis formation_Homo sapiens_hsa043200.62771145
88Allograft rejection_Homo sapiens_hsa053300.62602328
89Cardiac muscle contraction_Homo sapiens_hsa042600.62382276
90Axon guidance_Homo sapiens_hsa043600.62294663
91Glycerolipid metabolism_Homo sapiens_hsa005610.60596177
92Autoimmune thyroid disease_Homo sapiens_hsa053200.59514218
93Gastric acid secretion_Homo sapiens_hsa049710.54728793
94Pertussis_Homo sapiens_hsa051330.54615986
95Asthma_Homo sapiens_hsa053100.52985294
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.52431995
97Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51345794
98Retinol metabolism_Homo sapiens_hsa008300.51219292
99Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50016614
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49404116
101cAMP signaling pathway_Homo sapiens_hsa040240.49307048
102Ovarian steroidogenesis_Homo sapiens_hsa049130.48179016
103ABC transporters_Homo sapiens_hsa020100.48140869
104Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48064341
105Tryptophan metabolism_Homo sapiens_hsa003800.47181568
106Cholinergic synapse_Homo sapiens_hsa047250.46980872
107Type I diabetes mellitus_Homo sapiens_hsa049400.46583388
108beta-Alanine metabolism_Homo sapiens_hsa004100.46183168
109Metabolic pathways_Homo sapiens_hsa011000.45710035
110Toll-like receptor signaling pathway_Homo sapiens_hsa046200.44616628
111Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44429844
112Aldosterone synthesis and secretion_Homo sapiens_hsa049250.43655968
113Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43632740
114Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.41846070
115B cell receptor signaling pathway_Homo sapiens_hsa046620.41500089
116Oxytocin signaling pathway_Homo sapiens_hsa049210.39993046
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39783878
118GnRH signaling pathway_Homo sapiens_hsa049120.37115665
119T cell receptor signaling pathway_Homo sapiens_hsa046600.35834488
120Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35793158
121Phagosome_Homo sapiens_hsa041450.35528757
122Synaptic vesicle cycle_Homo sapiens_hsa047210.34473699
123Cyanoamino acid metabolism_Homo sapiens_hsa004600.34184535
124Ras signaling pathway_Homo sapiens_hsa040140.34130889
125Olfactory transduction_Homo sapiens_hsa047400.34009230
126MAPK signaling pathway_Homo sapiens_hsa040100.33862695
127Osteoclast differentiation_Homo sapiens_hsa043800.33748260
128Pentose and glucuronate interconversions_Homo sapiens_hsa000400.33393692
129Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.32877188
130Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.32818251
131Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.31963194

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