LDLRAD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lateral sprouting from an epithelium (GO:0060601)5.11704650
2paraxial mesoderm development (GO:0048339)4.50856188
3presynaptic membrane assembly (GO:0097105)4.43237170
4postsynaptic membrane organization (GO:0001941)4.22792793
5limb bud formation (GO:0060174)4.18630333
6presynaptic membrane organization (GO:0097090)4.09507703
7peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)4.08443882
8notochord development (GO:0030903)3.89785261
9regulation of cardioblast proliferation (GO:0003264)3.79916008
10regulation of secondary heart field cardioblast proliferation (GO:0003266)3.79916008
11axon ensheathment in central nervous system (GO:0032291)3.74597592
12central nervous system myelination (GO:0022010)3.74597592
13ganglion development (GO:0061548)3.63677693
14axon extension involved in axon guidance (GO:0048846)3.62781675
15neuron projection extension involved in neuron projection guidance (GO:1902284)3.62781675
16mesenchyme morphogenesis (GO:0072132)3.53628730
17negative regulation of glycogen biosynthetic process (GO:0045719)3.53095213
18endocardial cushion morphogenesis (GO:0003203)3.47630740
19response to pheromone (GO:0019236)3.38757431
20pyrimidine nucleobase catabolic process (GO:0006208)3.38533364
21mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.37222891
22chondrocyte development (GO:0002063)3.35705326
23dermatan sulfate biosynthetic process (GO:0030208)3.33639097
24regulation of heart morphogenesis (GO:2000826)3.31076986
25hippo signaling (GO:0035329)3.22082047
26atrial septum morphogenesis (GO:0060413)3.21843695
27lymph vessel development (GO:0001945)3.21299534
28cell migration involved in heart development (GO:0060973)3.19941992
29axonal fasciculation (GO:0007413)3.18815557
30outer ear morphogenesis (GO:0042473)3.15034150
31negative regulation of axon guidance (GO:1902668)3.13595584
32negative regulation of chondrocyte differentiation (GO:0032331)3.13342292
33regulation of cell proliferation involved in heart morphogenesis (GO:2000136)3.11348884
34mesenchymal cell proliferation (GO:0010463)3.09167375
35regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.09083955
36cochlea morphogenesis (GO:0090103)3.07674660
37regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.03981620
38dermatan sulfate metabolic process (GO:0030205)3.03571610
39neuron recognition (GO:0008038)3.03456868
40calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.03447819
41negative regulation of glycogen metabolic process (GO:0070874)3.03378185
42cell surface receptor signaling pathway involved in heart development (GO:0061311)3.00673318
43cell proliferation involved in kidney development (GO:0072111)2.99248619
44embryonic skeletal joint morphogenesis (GO:0060272)2.97257992
45prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.95225080
46G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.94519505
47negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.92565759
48radial glial cell differentiation (GO:0060019)2.90997837
49planar cell polarity pathway involved in neural tube closure (GO:0090179)2.89764032
50establishment of planar polarity (GO:0001736)2.89422456
51establishment of tissue polarity (GO:0007164)2.89422456
52epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.88706938
53endocardial cushion development (GO:0003197)2.88310909
54neuron cell-cell adhesion (GO:0007158)2.88172200
55regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.87210320
56cartilage condensation (GO:0001502)2.86395445
57cell aggregation (GO:0098743)2.86395445
58somite development (GO:0061053)2.85694334
59regulation of axon guidance (GO:1902667)2.85461034
60embryonic cranial skeleton morphogenesis (GO:0048701)2.85014174
61chondrocyte proliferation (GO:0035988)2.84617792
62asymmetric protein localization (GO:0008105)2.84012669
63regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.81782792
64regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.81706099
65retinal ganglion cell axon guidance (GO:0031290)2.80484412
66regulation of SMAD protein import into nucleus (GO:0060390)2.80134681
67glomerulus development (GO:0032835)2.77681224
68cell proliferation involved in metanephros development (GO:0072203)2.77461132
69long-chain fatty acid biosynthetic process (GO:0042759)2.74825881
70collagen fibril organization (GO:0030199)2.72585863
71digestive tract morphogenesis (GO:0048546)2.70788262
72regulation of non-canonical Wnt signaling pathway (GO:2000050)2.67990832
73negative chemotaxis (GO:0050919)2.67439139
74regulation of chemokine-mediated signaling pathway (GO:0070099)2.66577063
75positive regulation of hormone biosynthetic process (GO:0046886)2.66292652
76organ formation (GO:0048645)2.65983176
77cranial nerve morphogenesis (GO:0021602)2.65923812
78regulation of mesenchymal cell proliferation (GO:0010464)2.65672062
79auditory behavior (GO:0031223)2.65647056
80heart valve morphogenesis (GO:0003179)2.64712087
81negative regulation of transcription regulatory region DNA binding (GO:2000678)2.64663817
82morphogenesis of an epithelial sheet (GO:0002011)2.64476523
83bone trabecula formation (GO:0060346)2.64160703
84mesenchymal cell development (GO:0014031)2.64031519
85negative regulation of axon extension involved in axon guidance (GO:0048843)2.63600592
86central nervous system projection neuron axonogenesis (GO:0021952)2.62902658
87branching involved in prostate gland morphogenesis (GO:0060442)2.62716193
88oligodendrocyte differentiation (GO:0048709)2.61042145
89ventricular trabecula myocardium morphogenesis (GO:0003222)2.61010926
90positive regulation of synapse assembly (GO:0051965)2.60030170
91pericardium development (GO:0060039)2.59767928
92Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.58980155
93atrioventricular valve morphogenesis (GO:0003181)2.57956509
94cranial suture morphogenesis (GO:0060363)2.56835644
95Notch signaling involved in heart development (GO:0061314)2.56331489
96negative regulation of embryonic development (GO:0045992)2.56156457
97mesenchymal cell differentiation (GO:0048762)2.56049961
98negative regulation of catenin import into nucleus (GO:0035414)2.56043548
99negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.55476220
100regulation of establishment of planar polarity (GO:0090175)2.55460438
101positive regulation of mesenchymal cell proliferation (GO:0002053)2.54857391
102artery development (GO:0060840)2.54595314
103negative regulation of cartilage development (GO:0061037)2.54034789
104regulation of axon extension involved in axon guidance (GO:0048841)2.51712766
105heart valve formation (GO:0003188)2.51537344
106cartilage development (GO:0051216)2.51461853
107regulation of organ formation (GO:0003156)2.49896402
108mechanosensory behavior (GO:0007638)2.49473446
109hindlimb morphogenesis (GO:0035137)2.49032890
110cell-cell signaling involved in cell fate commitment (GO:0045168)2.48610721
111neural crest cell development (GO:0014032)2.48478383
112epithelial to mesenchymal transition (GO:0001837)2.47665130
113negative regulation of smoothened signaling pathway (GO:0045879)2.47657122
114negative regulation of oligodendrocyte differentiation (GO:0048715)2.47515927
115ephrin receptor signaling pathway (GO:0048013)2.46398924
116middle ear morphogenesis (GO:0042474)2.45708457
117cerebral cortex cell migration (GO:0021795)2.45379332
118axon extension (GO:0048675)2.44904435
119neuronal stem cell maintenance (GO:0097150)2.44804471
120apical protein localization (GO:0045176)2.44485612
121somatic stem cell division (GO:0048103)2.43590831
122embryonic digit morphogenesis (GO:0042733)2.43283103
123nonmotile primary cilium assembly (GO:0035058)2.42667629
124keratan sulfate catabolic process (GO:0042340)2.42384844
125nucleobase catabolic process (GO:0046113)2.42249117
126craniofacial suture morphogenesis (GO:0097094)2.42098130
127developmental induction (GO:0031128)2.42077491
128kidney morphogenesis (GO:0060993)2.41597560
129stem cell development (GO:0048864)2.41558031
130regulation of fever generation (GO:0031620)2.40974480
131cerebral cortex radially oriented cell migration (GO:0021799)2.40892417
132regulation of somitogenesis (GO:0014807)2.40801145
133olfactory bulb development (GO:0021772)2.40123643
134positive regulation of neuroblast proliferation (GO:0002052)2.39933016
135embryonic camera-type eye development (GO:0031076)2.39330345
136positive regulation of SMAD protein import into nucleus (GO:0060391)2.38503711
137mesenchymal-epithelial cell signaling (GO:0060638)2.38476858
138limb development (GO:0060173)2.38258867
139appendage development (GO:0048736)2.38258867
140enteric nervous system development (GO:0048484)2.37876524
141positive regulation of stem cell differentiation (GO:2000738)2.37636706
142lens fiber cell development (GO:0070307)2.37462812
143exocrine pancreas development (GO:0031017)2.37430060
144cellular response to cholesterol (GO:0071397)2.36372961
145generation of neurons (GO:0048699)2.36283856
146establishment of integrated proviral latency (GO:0075713)2.33564410
147synapse assembly (GO:0007416)2.32986223
148vocalization behavior (GO:0071625)2.32130342
149central nervous system neuron axonogenesis (GO:0021955)2.31402609
150spinal cord development (GO:0021510)2.30089489
151convergent extension (GO:0060026)2.29976035
152response to auditory stimulus (GO:0010996)2.29857959
153establishment of nucleus localization (GO:0040023)2.29188347
154protein localization to kinetochore (GO:0034501)2.27373040
155hair follicle development (GO:0001942)2.25144528
156cardiac right ventricle morphogenesis (GO:0003215)2.25108221
157cell proliferation in forebrain (GO:0021846)2.22333177
158negative regulation of vascular permeability (GO:0043116)2.21712434
159positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.21095577
160positive regulation of cell cycle G2/M phase transition (GO:1902751)2.21095577
161regulation of development, heterochronic (GO:0040034)2.19961231
162glial cell differentiation (GO:0010001)2.19906199
163regulation of timing of cell differentiation (GO:0048505)2.19522161
164protein localization to synapse (GO:0035418)2.18197588
165regulation of respiratory system process (GO:0044065)2.18167805
166membrane assembly (GO:0071709)2.16808949
167cranial nerve development (GO:0021545)2.16570375
168regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.16464591
169intraciliary transport (GO:0042073)2.15262048
170branching involved in salivary gland morphogenesis (GO:0060445)2.13921698
171cochlea development (GO:0090102)2.13589252
172epithelial tube branching involved in lung morphogenesis (GO:0060441)2.13032409
173dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.12113171
174midbrain development (GO:0030901)2.11206185
175negative regulation of astrocyte differentiation (GO:0048712)2.10193497
176myelination in peripheral nervous system (GO:0022011)2.09960013
177peripheral nervous system axon ensheathment (GO:0032292)2.09960013
178heart trabecula morphogenesis (GO:0061384)2.09854441
179ventricular cardiac muscle cell development (GO:0055015)2.09829717

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.11740924
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.73141168
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.62635774
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.17962414
5TP63_19390658_ChIP-ChIP_HaCaT_Human2.86248273
6NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.64728003
7AR_21572438_ChIP-Seq_LNCaP_Human2.64074308
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.61306499
9POU5F1_16153702_ChIP-ChIP_HESCs_Human2.54001905
10WT1_19549856_ChIP-ChIP_CCG9911_Human2.51937951
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.46482437
12PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.43510043
13CBX2_27304074_Chip-Seq_ESCs_Mouse2.39630562
14HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.35761437
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.33898620
16RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.30955022
17E2F7_22180533_ChIP-Seq_HELA_Human2.25793371
18EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.25744031
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09041166
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97341063
21* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.95626117
22EZH2_27304074_Chip-Seq_ESCs_Mouse1.95397277
23FOXM1_23109430_ChIP-Seq_U2OS_Human1.88260490
24FUS_26573619_Chip-Seq_HEK293_Human1.85885027
25ISL1_27105846_Chip-Seq_CPCs_Mouse1.79988189
26PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.79255007
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.71147700
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.70972845
29KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.70444794
30KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.70444794
31KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.70444794
32RING1B_27294783_Chip-Seq_NPCs_Mouse1.68481000
33KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.67588034
34* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.64411469
35EWS_26573619_Chip-Seq_HEK293_Human1.63854665
36AR_21909140_ChIP-Seq_LNCAP_Human1.62721498
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62555963
38CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.61991383
39GBX2_23144817_ChIP-Seq_PC3_Human1.61082123
40TAF15_26573619_Chip-Seq_HEK293_Human1.61031697
41EZH2_18974828_ChIP-Seq_MESCs_Mouse1.56394981
42RNF2_18974828_ChIP-Seq_MESCs_Mouse1.56394981
43RNF2_27304074_Chip-Seq_ESCs_Mouse1.54046048
44EP300_21415370_ChIP-Seq_HL-1_Mouse1.53507986
45* P300_19829295_ChIP-Seq_ESCs_Human1.52866138
46OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51119946
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.51085239
48SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.48775840
49SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47059857
50NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.46682656
51* SOX9_26525672_Chip-Seq_HEART_Mouse1.43930954
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.43786600
53TP53_20018659_ChIP-ChIP_R1E_Mouse1.43295848
54* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.42992477
55KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.41825697
56ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.38500055
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.36596960
58SALL4_18804426_ChIP-ChIP_XEN_Mouse1.36121250
59SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35826211
60FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.35130949
61JARID2_20064375_ChIP-Seq_MESCs_Mouse1.34786329
62TCF3_18692474_ChIP-Seq_MEFs_Mouse1.34510866
63* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33823843
64SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.33516971
65* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.33380707
66SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.33368750
67SOX2_16153702_ChIP-ChIP_HESCs_Human1.32808439
68POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.32499627
69TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.32466100
70IGF1R_20145208_ChIP-Seq_DFB_Human1.32398361
71CJUN_26792858_Chip-Seq_BT549_Human1.31437638
72* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31153492
73TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.30486201
74MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29192879
75* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.28806249
76* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.28709400
77CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28526305
78BRD4_25478319_ChIP-Seq_HGPS_Human1.27979271
79* SMAD4_21799915_ChIP-Seq_A2780_Human1.25642790
80NFIB_24661679_ChIP-Seq_LUNG_Mouse1.25551244
81SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.25386654
82* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23342117
83KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.23209850
84* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.22201529
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.20131446
86* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.20021718
87TP63_17297297_ChIP-ChIP_HaCaT_Human1.18745569
88SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.17233780
89CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17019049
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.16660795
91CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.15595693
92CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.15438321
93PIAS1_25552417_ChIP-Seq_VCAP_Human1.14825885
94RING1B_27294783_Chip-Seq_ESCs_Mouse1.14386791
95TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13372286
96JARID2_20075857_ChIP-Seq_MESCs_Mouse1.13114347
97RNF2_27304074_Chip-Seq_NSC_Mouse1.12752027
98TBX3_20139965_ChIP-Seq_ESCs_Mouse1.11492542
99TBX3_20139965_ChIP-Seq_MESCs_Mouse1.11379757
100* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10393292
101CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.10205013
102ESR1_20079471_ChIP-ChIP_T-47D_Human1.09904033
103OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.08596107
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08547005
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08547005
106NR3C1_23031785_ChIP-Seq_PC12_Mouse1.08052044
107* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06321435
108CDX2_19796622_ChIP-Seq_MESCs_Mouse1.04749382
109ESR1_21235772_ChIP-Seq_MCF-7_Human1.04365454
110RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.03549478
111ZNF274_21170338_ChIP-Seq_K562_Hela1.03491524
112NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.02951438
113DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02870425
114* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.02735370
115* SMAD3_21741376_ChIP-Seq_EPCs_Human1.02694192
116* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02487804
117TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.02467406
118CLOCK_20551151_ChIP-Seq_293T_Human1.01028015
119NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.00881308
120NRF2_20460467_ChIP-Seq_MEFs_Mouse1.00881308
121EZH2_22144423_ChIP-Seq_EOC_Human0.99645281
122TP53_18474530_ChIP-ChIP_U2OS_Human0.99546688
123* ARNT_22903824_ChIP-Seq_MCF-7_Human0.99293065
124NANOG_16153702_ChIP-ChIP_HESCs_Human0.99291091
125HIF1A_21447827_ChIP-Seq_MCF-7_Human0.99150378
126* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99030861
127SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98956865
128YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98828028
129TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96885933
130POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.96816907
131AHR_22903824_ChIP-Seq_MCF-7_Human0.96408610

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology3.88187893
2MP0010030_abnormal_orbit_morphology3.36774076
3MP0008438_abnormal_cutaneous_collagen3.26960042
4MP0003880_abnormal_central_pattern3.21157981
5MP0000566_synostosis2.99139220
6MP0002249_abnormal_larynx_morphology2.75816814
7MP0002282_abnormal_trachea_morphology2.49111025
8MP0002938_white_spotting2.48361214
9MP0003122_maternal_imprinting2.40570856
10MP0009250_abnormal_appendicular_skeleto2.39435672
11MP0000537_abnormal_urethra_morphology2.32354303
12MP0004272_abnormal_basement_membrane2.22608970
13MP0003121_genomic_imprinting2.20157723
14MP0004134_abnormal_chest_morphology2.19357751
15MP0000049_abnormal_middle_ear2.19332530
16MP0005275_abnormal_skin_tensile2.14531430
17MP0005171_absent_coat_pigmentation2.10746495
18MP0003937_abnormal_limbs/digits/tail_de2.04027035
19MP0005248_abnormal_Harderian_gland1.99820497
20MP0003385_abnormal_body_wall1.98717434
21MP0000762_abnormal_tongue_morphology1.95733863
22MP0005508_abnormal_skeleton_morphology1.95214123
23MP0002653_abnormal_ependyma_morphology1.91315619
24MP0001293_anophthalmia1.89137242
25MP0003941_abnormal_skin_development1.89030165
26MP0003755_abnormal_palate_morphology1.85633342
27MP0000579_abnormal_nail_morphology1.84808487
28MP0001529_abnormal_vocalization1.84706758
29MP0002108_abnormal_muscle_morphology1.78745605
30MP0003942_abnormal_urinary_system1.74507963
31MP0000163_abnormal_cartilage_morphology1.62968391
32MP0002822_catalepsy1.62603320
33MP0002932_abnormal_joint_morphology1.58765803
34MP0009384_cardiac_valve_regurgitation1.56884755
35MP0002116_abnormal_craniofacial_bone1.55322964
36MP0003935_abnormal_craniofacial_develop1.52027458
37MP0002234_abnormal_pharynx_morphology1.48495875
38MP0000428_abnormal_craniofacial_morphol1.48384541
39MP0002233_abnormal_nose_morphology1.48196781
40MP0000432_abnormal_head_morphology1.47357255
41MP0000733_abnormal_muscle_development1.44764040
42MP0009053_abnormal_anal_canal1.44153866
43MP0001270_distended_abdomen1.42260522
44MP0002736_abnormal_nociception_after1.41761960
45MP0001879_abnormal_lymphatic_vessel1.40375497
46MP0001984_abnormal_olfaction1.39962802
47MP0000534_abnormal_ureter_morphology1.37472283
48MP0002102_abnormal_ear_morphology1.35687438
49MP0001299_abnormal_eye_distance/1.35545626
50MP0003123_paternal_imprinting1.33564374
51MP0002697_abnormal_eye_size1.33211734
52MP0001286_abnormal_eye_development1.31919315
53MP0002109_abnormal_limb_morphology1.31733316
54MP0003950_abnormal_plasma_membrane1.31187653
55MP0002089_abnormal_postnatal_growth/wei1.30259377
56MP0005623_abnormal_meninges_morphology1.30096073
57MP0005499_abnormal_olfactory_system1.28722801
58MP0005394_taste/olfaction_phenotype1.28722801
59MP0004133_heterotaxia1.28580476
60MP0005423_abnormal_somatic_nervous1.28007614
61MP0000955_abnormal_spinal_cord1.24046583
62MP0006276_abnormal_autonomic_nervous1.23714870
63MP0004270_analgesia1.23056233
64MP0003115_abnormal_respiratory_system1.22518527
65MP0004885_abnormal_endolymph1.22366051
66MP0003315_abnormal_perineum_morphology1.21157243
67MP0000778_abnormal_nervous_system1.20176661
68MP0002092_abnormal_eye_morphology1.19736574
69MP0004859_abnormal_synaptic_plasticity1.18102974
70MP0003279_aneurysm1.17521369
71MP0002115_abnormal_skeleton_extremities1.17411045
72MP0002114_abnormal_axial_skeleton1.16664140
73MP0002184_abnormal_innervation1.16093382
74MP0008789_abnormal_olfactory_epithelium1.15263305
75MP0000383_abnormal_hair_follicle1.14630902
76MP0001958_emphysema1.14512891
77MP0001346_abnormal_lacrimal_gland1.14022726
78MP0002113_abnormal_skeleton_development1.13621912
79MP0003890_abnormal_embryonic-extraembry1.13161880
80MP0000767_abnormal_smooth_muscle1.12283883
81MP0003938_abnormal_ear_development1.11889547
82MP0003011_delayed_dark_adaptation1.09835031
83MP0001177_atelectasis1.09228087
84MP0006054_spinal_hemorrhage1.09091599
85MP0002896_abnormal_bone_mineralization1.08974424
86MP0002111_abnormal_tail_morphology1.08139733
87MP0002152_abnormal_brain_morphology1.07337744
88MP0002009_preneoplasia1.05985532
89MP0000026_abnormal_inner_ear1.04651900
90MP0005257_abnormal_intraocular_pressure1.03718673
91MP0004197_abnormal_fetal_growth/weight/1.03515581
92MP0001486_abnormal_startle_reflex1.01527479
93MP0002557_abnormal_social/conspecific_i1.01445010
94MP0005253_abnormal_eye_physiology1.00206876
95MP0010678_abnormal_skin_adnexa0.98662768
96MP0005197_abnormal_uvea_morphology0.98608842
97MP0003878_abnormal_ear_physiology0.96724986
98MP0005377_hearing/vestibular/ear_phenot0.96724986
99MP0002751_abnormal_autonomic_nervous0.96703532
100MP0003787_abnormal_imprinting0.96580030
101MP0003283_abnormal_digestive_organ0.95725859
102MP0002084_abnormal_developmental_patter0.94473422
103MP0002177_abnormal_outer_ear0.94340574
104MP0002085_abnormal_embryonic_tissue0.93554022
105MP0002572_abnormal_emotion/affect_behav0.92625823
106MP0003634_abnormal_glial_cell0.92600791
107MP0006292_abnormal_olfactory_placode0.92565331
108MP0006072_abnormal_retinal_apoptosis0.92333058
109MP0002734_abnormal_mechanical_nocicepti0.92329749
110MP0000647_abnormal_sebaceous_gland0.92054571
111MP0002752_abnormal_somatic_nervous0.91899727
112MP0003635_abnormal_synaptic_transmissio0.90569865
113MP0000003_abnormal_adipose_tissue0.90480361
114MP0000516_abnormal_urinary_system0.90110149
115MP0005367_renal/urinary_system_phenotyp0.90110149
116MP0002063_abnormal_learning/memory/cond0.89862984
117MP0000569_abnormal_digit_pigmentation0.89697239
118MP0003861_abnormal_nervous_system0.89565124
119MP0002882_abnormal_neuron_morphology0.89228974
120MP0002098_abnormal_vibrissa_morphology0.87681501
121MP0003119_abnormal_digestive_system0.87077793
122MP0002933_joint_inflammation0.86675640
123MP0008932_abnormal_embryonic_tissue0.85190814
124MP0000631_abnormal_neuroendocrine_gland0.84393631
125MP0005391_vision/eye_phenotype0.83568288
126MP0004811_abnormal_neuron_physiology0.83354293
127MP0001188_hyperpigmentation0.82416890
128MP0002638_abnormal_pupillary_reflex0.81933553
129MP0003136_yellow_coat_color0.81335644
130MP0003705_abnormal_hypodermis_morpholog0.81070839
131MP0005390_skeleton_phenotype0.81069399
132MP0003567_abnormal_fetal_cardiomyocyte0.79883688
133MP0001485_abnormal_pinna_reflex0.79669210
134MP0002081_perinatal_lethality0.79454457
135MP0000613_abnormal_salivary_gland0.77964371
136MP0002925_abnormal_cardiovascular_devel0.77869097
137MP0000462_abnormal_digestive_system0.75767575
138MP0000467_abnormal_esophagus_morphology0.75712812
139MP0008995_early_reproductive_senescence0.71150560
140MP0000372_irregular_coat_pigmentation0.70401620
141MP0005193_abnormal_anterior_eye0.70203237
142MP0005187_abnormal_penis_morphology0.70103954

Predicted human phenotypes

RankGene SetZ-score
1Epiphyseal dysplasia (HP:0002656)3.56280824
2Short 4th metacarpal (HP:0010044)3.50871851
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.50871851
4Neonatal short-limb short stature (HP:0008921)3.42060518
5Hypoplastic ischia (HP:0003175)3.20935848
6Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.02139270
7Esophageal atresia (HP:0002032)2.90526391
8Vitreoretinal degeneration (HP:0000655)2.86042176
9Coronal craniosynostosis (HP:0004440)2.73047243
10Abnormality of the ischium (HP:0003174)2.71636877
11Anophthalmia (HP:0000528)2.69204771
12Abnormality of the 4th metacarpal (HP:0010012)2.62606952
13Midline defect of the nose (HP:0004122)2.51382626
14Split foot (HP:0001839)2.50720547
15Abnormality of incisor morphology (HP:0011063)2.50051138
16Shallow orbits (HP:0000586)2.47034361
17Gastrointestinal atresia (HP:0002589)2.39770840
18Mild short stature (HP:0003502)2.38778362
19Aplasia of the musculature (HP:0100854)2.38714946
20Mesomelia (HP:0003027)2.34861679
21Partial duplication of the phalanx of hand (HP:0009999)2.30870417
22Abnormality of the phalanges of the 2nd finger (HP:0009541)2.28063771
23Abnormality of the parietal bone (HP:0002696)2.25949363
24Absent septum pellucidum (HP:0001331)2.24587299
25Abnormality of the lower motor neuron (HP:0002366)2.22662012
26Alacrima (HP:0000522)2.21691111
27Partial duplication of thumb phalanx (HP:0009944)2.20924737
28Large earlobe (HP:0009748)2.20604609
29Hip contracture (HP:0003273)2.15030180
30Broad toe (HP:0001837)2.13848488
31Synostosis of carpal bones (HP:0005048)2.12689524
32Abnormality of the diencephalon (HP:0010662)2.12151511
33Flat capital femoral epiphysis (HP:0003370)2.10654783
34Irregular epiphyses (HP:0010582)2.09534075
35Abnormality of the incisor (HP:0000676)2.09173796
36Limited hip movement (HP:0008800)2.07446370
37Trigonocephaly (HP:0000243)2.06837474
38Broad thumb (HP:0011304)2.02195208
39Hemivertebrae (HP:0002937)2.01573526
40Short tibia (HP:0005736)2.01410009
41Abnormality of the distal phalanx of the thumb (HP:0009617)2.00957254
42Abnormality of the septum pellucidum (HP:0007375)1.98353542
43Shawl scrotum (HP:0000049)1.96915615
44Protrusio acetabuli (HP:0003179)1.96912906
45Oligodactyly (hands) (HP:0001180)1.96906849
46Megalencephaly (HP:0001355)1.96843828
47Broad hallux (HP:0010055)1.96199442
48Aortic dissection (HP:0002647)1.96083963
49Preaxial hand polydactyly (HP:0001177)1.95948474
50Preaxial foot polydactyly (HP:0001841)1.95316160
51Pulmonary artery stenosis (HP:0004415)1.95134833
52Down-sloping shoulders (HP:0200021)1.95094832
53Broad phalanx (HP:0006009)1.94623828
54Abnormality of the middle phalanges of the toes (HP:0010183)1.94505884
55Long clavicles (HP:0000890)1.94108981
56Abnormality of the pubic bones (HP:0003172)1.93275046
57Bell-shaped thorax (HP:0001591)1.93007728
58Aplasia involving bones of the upper limbs (HP:0009823)1.92122553
59Aplasia of the phalanges of the hand (HP:0009802)1.92122553
60Aplasia involving bones of the extremities (HP:0009825)1.92122553
61Broad long bones (HP:0005622)1.91722202
62Vertebral arch anomaly (HP:0008438)1.91326850
63Hypoplastic left heart (HP:0004383)1.91290612
64Sprengel anomaly (HP:0000912)1.89148029
65Pterygium (HP:0001059)1.88015731
66Hemiparesis (HP:0001269)1.87396422
67Oligodactyly (HP:0012165)1.86633026
68Hypoplastic heart (HP:0001961)1.86288518
69Mixed hearing impairment (HP:0000410)1.84306550
70Focal motor seizures (HP:0011153)1.83290021
71Abnormal number of incisors (HP:0011064)1.83175479
72Aplasia/Hypoplasia of the tibia (HP:0005772)1.81839135
73Absent epiphyses (HP:0010577)1.81812490
74Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.81812490
75Exostoses (HP:0100777)1.81690700
76Broad metatarsal (HP:0001783)1.80871875
77Hepatoblastoma (HP:0002884)1.80803526
78Abnormal auditory evoked potentials (HP:0006958)1.80583355
79Broad phalanges of the hand (HP:0009768)1.80406245
80Ankle contracture (HP:0006466)1.79725495
81Abnormality of the 2nd finger (HP:0004100)1.79707298
82Hypoplastic pelvis (HP:0008839)1.79613270
83White forelock (HP:0002211)1.78694611
84Carpal synostosis (HP:0009702)1.78668445
85Decreased lacrimation (HP:0000633)1.77968114
86Renal hypoplasia (HP:0000089)1.77941662
87Aplasia/Hypoplasia of the sternum (HP:0006714)1.77905889
88Cupped ribs (HP:0000887)1.77048020
89Median cleft lip (HP:0000161)1.77017477
90Abnormal vertebral ossification (HP:0100569)1.76219282
91Broad finger (HP:0001500)1.76075580
92Follicular hyperkeratosis (HP:0007502)1.75931147
93Turricephaly (HP:0000262)1.75425210
94Limb dystonia (HP:0002451)1.75117944
95Colon cancer (HP:0003003)1.74670947
96Premature rupture of membranes (HP:0001788)1.71340472
97Renal dysplasia (HP:0000110)1.71252372
98Retinal dysplasia (HP:0007973)1.71190673
99Micromelia (HP:0002983)1.70581481
100Vertebral clefting (HP:0008428)1.69828389
101Microglossia (HP:0000171)1.69000023
102Duplication of thumb phalanx (HP:0009942)1.68759071
103Patchy hypopigmentation of hair (HP:0011365)1.67998265
104Septo-optic dysplasia (HP:0100842)1.67604481
105True hermaphroditism (HP:0010459)1.67465558
106Rib fusion (HP:0000902)1.67006218
107Bifid tongue (HP:0010297)1.66082772
108Drooling (HP:0002307)1.65873304
109Fibular hypoplasia (HP:0003038)1.65659192
110Limited elbow extension (HP:0001377)1.65612817
111Aortic aneurysm (HP:0004942)1.65286922
112Increased number of teeth (HP:0011069)1.64952383
113Thin ribs (HP:0000883)1.64669003
114Occipital encephalocele (HP:0002085)1.64436172
115Arterial tortuosity (HP:0005116)1.64329657
116Short ribs (HP:0000773)1.63679950
117Intestinal atresia (HP:0011100)1.62771416
118Cutaneous finger syndactyly (HP:0010554)1.62579661
119Wide anterior fontanel (HP:0000260)1.61565144
120Short hallux (HP:0010109)1.61501884
121Glioma (HP:0009733)1.60799584
122Deviation of the thumb (HP:0009603)1.60684099
123Bilateral microphthalmos (HP:0007633)1.60603685
124Cortical dysplasia (HP:0002539)1.60125688
125Renal duplication (HP:0000075)1.59895957
126Type 1 muscle fiber predominance (HP:0003803)1.59404517
127Abnormality of dentin (HP:0010299)1.59287681
128Adrenal hypoplasia (HP:0000835)1.59052183
129Morphological abnormality of the middle ear (HP:0008609)1.58836630
130Deep philtrum (HP:0002002)1.58484188
131Neoplasm of the oral cavity (HP:0100649)1.58481247
132Tracheomalacia (HP:0002779)1.58076141
133Postnatal microcephaly (HP:0005484)1.57641386
134Abnormality of the antihelix (HP:0009738)1.57538332
135Cutaneous syndactyly (HP:0012725)1.57526192
136High anterior hairline (HP:0009890)1.57362495
137Aplasia/Hypoplasia of the fibula (HP:0006492)1.57169810
138Abnormality of the phalanges of the hallux (HP:0010057)1.56496443
139Medulloblastoma (HP:0002885)1.55929753
140Aplasia/Hypoplasia of the clavicles (HP:0006710)1.55451619
141Small epiphyses (HP:0010585)1.55304861
142Proximal placement of thumb (HP:0009623)1.54708554
143Aplasia/Hypoplasia of the breasts (HP:0010311)1.53091862
144Maternal diabetes (HP:0009800)1.53062889
145Increased nuchal translucency (HP:0010880)1.52826427
146Omphalocele (HP:0001539)1.52755970
147Aplasia/Hypoplasia of the tongue (HP:0010295)1.52031387
148Popliteal pterygium (HP:0009756)1.51466426
149Hypoplasia of the capital femoral epiphysis (HP:0003090)1.51450302
150Optic nerve hypoplasia (HP:0000609)1.48490460
151Overriding aorta (HP:0002623)1.48095170
152Heterochromia iridis (HP:0001100)1.47224714
153Depressed nasal tip (HP:0000437)1.47123330
154Postaxial hand polydactyly (HP:0001162)1.45953041
155Genital tract atresia (HP:0001827)1.45238861
156Breast aplasia (HP:0100783)1.42500105
157Absent eyebrow (HP:0002223)1.41512882
158Narrow forehead (HP:0000341)1.40063752
159Chorioretinal coloboma (HP:0000567)1.39205976
160Vaginal atresia (HP:0000148)1.38798264
161Sclerocornea (HP:0000647)1.38245439
162Anterior segment dysgenesis (HP:0007700)1.37734062
163Aqueductal stenosis (HP:0002410)1.37147403
164Postaxial foot polydactyly (HP:0001830)1.37136725
165Abnormal lung lobation (HP:0002101)1.35506841
166Glossoptosis (HP:0000162)1.34937171
167Hypotelorism (HP:0000601)1.33983422
168Cystic hygroma (HP:0000476)1.33820063

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.06428861
2MARK13.27626540
3EPHB23.26246273
4PNCK3.15968850
5MKNK12.84292602
6DDR22.83912940
7WNK32.74873550
8CASK2.61868840
9TNIK2.45334841
10EPHA42.36516153
11ZAK2.27439318
12WEE12.21356878
13NUAK12.16369046
14DMPK2.11846908
15SIK12.09849561
16ERBB31.98176677
17STK38L1.78290723
18MKNK21.74171016
19CSNK1A1L1.74137983
20MUSK1.70611191
21CDC71.68994201
22SRPK11.68847135
23TRIM281.66188628
24BCR1.62487301
25TSSK61.59942717
26LMTK21.58196634
27MET1.57255166
28NTRK11.49777604
29PBK1.48850809
30STK391.45450946
31FGFR21.44400369
32MAP3K41.40655097
33STK31.39061694
34CDK121.37351190
35TGFBR11.35795813
36CDK71.32791648
37BUB11.32449961
38PRKD31.30115809
39DYRK21.25989958
40PLK31.25909036
41MAP2K71.25448331
42FER1.20981011
43SIK31.16428470
44ERBB41.16033927
45LIMK11.14062647
46CSNK1G31.12895793
47MINK11.12542246
48BRD41.10743901
49ERBB21.10192828
50FGFR11.09813160
51MAPKAPK51.05096888
52CSNK1G11.03432369
53PAK21.03410190
54YES11.03328964
55VRK21.02612136
56SGK4941.00494736
57SGK2231.00494736
58ROCK20.97774251
59CAMK1G0.97351502
60CDK80.96094088
61CAMK1D0.96035432
62BMPR1B0.93135840
63ROCK10.92450981
64TGFBR20.91256455
65CDK60.91159367
66PDGFRA0.90831725
67ICK0.89529468
68CHEK20.88236740
69NTRK30.88065494
70ATR0.87389778
71TTK0.86664430
72PAK40.85655342
73MELK0.83644430
74MOS0.83567473
75EPHA30.81329129
76CDK180.78080413
77PLK40.76853247
78MYLK0.76279484
79CLK10.75594490
80OBSCN0.75147843
81LATS20.74087599
82OXSR10.72408474
83PAK60.72393269
84CDK150.72367127
85CDK140.71586482
86UHMK10.71381813
87MAPK150.71193059
88MAPK130.70449216
89CSNK1G20.70094649
90NEK90.69309405
91PRKCG0.68376813
92NEK10.68222465
93MAP3K100.66172241
94CDK11A0.65807630
95WNK10.64903064
96MTOR0.64537833
97IRAK20.64088634
98BRSK10.61571486
99CHEK10.60367083
100TIE10.59928348
101AKT30.59167736
102VRK10.58357899
103PASK0.58111255
104AURKB0.57638535
105GSK3A0.57340273
106CDK10.56907766
107DYRK1B0.56893731
108TYRO30.56754484
109AKT10.56622460
110ILK0.56477489
111CAMK2B0.56372724
112PLK10.56187626
113TAF10.56173434
114CHUK0.56084089
115AKT20.54916283
116EEF2K0.54323183
117PRKCE0.54290246
118EIF2AK20.52874680
119KSR10.52766441
120MAP4K20.52108599
121ATM0.51737689
122NTRK20.51383992
123WNK40.50883503
124CDK30.50135157
125RPS6KA40.50030954
126DYRK30.49991043
127EIF2AK30.49282867
128STK40.48263855
129BRSK20.48189574
130NEK60.47304185
131PLK20.46872193
132MARK20.45246435
133PKN10.44666719
134MAPK10.43430012
135TESK20.43343373
136PTK20.42553142
137PAK30.41396503
138DYRK1A0.40961494

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052173.51352343
2Hedgehog signaling pathway_Homo sapiens_hsa043402.80596005
3Hippo signaling pathway_Homo sapiens_hsa043902.59127270
4TGF-beta signaling pathway_Homo sapiens_hsa043502.54380947
5ECM-receptor interaction_Homo sapiens_hsa045122.46278211
6Steroid biosynthesis_Homo sapiens_hsa001002.44096087
7Adherens junction_Homo sapiens_hsa045202.35985161
8Notch signaling pathway_Homo sapiens_hsa043302.31464348
9Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.24959655
10Cell cycle_Homo sapiens_hsa041102.21646497
11Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045502.07052566
12MicroRNAs in cancer_Homo sapiens_hsa052061.91727001
13Axon guidance_Homo sapiens_hsa043601.79865129
14Wnt signaling pathway_Homo sapiens_hsa043101.76871344
15Focal adhesion_Homo sapiens_hsa045101.71292627
16Protein digestion and absorption_Homo sapiens_hsa049741.69697930
17Non-homologous end-joining_Homo sapiens_hsa034501.61241683
18Spliceosome_Homo sapiens_hsa030401.60521304
19Proteoglycans in cancer_Homo sapiens_hsa052051.55441422
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.52424623
21Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.51360223
22Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.50775701
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.46220560
24Base excision repair_Homo sapiens_hsa034101.42679283
25Prostate cancer_Homo sapiens_hsa052151.41571895
26Pathways in cancer_Homo sapiens_hsa052001.40300053
27Tight junction_Homo sapiens_hsa045301.40120689
28Nicotine addiction_Homo sapiens_hsa050331.40017476
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39949958
30Cocaine addiction_Homo sapiens_hsa050301.35400304
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.34785341
32DNA replication_Homo sapiens_hsa030301.34485548
33PI3K-Akt signaling pathway_Homo sapiens_hsa041511.32514210
34Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.31895075
35Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.30269569
36Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.27835659
37Basal transcription factors_Homo sapiens_hsa030221.24575539
38Colorectal cancer_Homo sapiens_hsa052101.23721655
39Mismatch repair_Homo sapiens_hsa034301.23505660
40Renal cell carcinoma_Homo sapiens_hsa052111.23464773
41Lysine degradation_Homo sapiens_hsa003101.20417808
42Melanogenesis_Homo sapiens_hsa049161.20303627
43Fanconi anemia pathway_Homo sapiens_hsa034601.18775840
44mRNA surveillance pathway_Homo sapiens_hsa030151.18085890
45Transcriptional misregulation in cancer_Homo sapiens_hsa052021.16440164
46Glutamatergic synapse_Homo sapiens_hsa047241.10431041
47Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.10041656
48RNA degradation_Homo sapiens_hsa030181.09459637
49Dopaminergic synapse_Homo sapiens_hsa047281.08762740
50Viral myocarditis_Homo sapiens_hsa054161.08567742
51Small cell lung cancer_Homo sapiens_hsa052221.08041697
52Ovarian steroidogenesis_Homo sapiens_hsa049131.07657675
53p53 signaling pathway_Homo sapiens_hsa041151.07348153
54Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.06516274
55Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.06277463
56Chronic myeloid leukemia_Homo sapiens_hsa052201.05828079
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.02976645
58One carbon pool by folate_Homo sapiens_hsa006701.01855105
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.01121930
60Melanoma_Homo sapiens_hsa052181.00143319
61Ether lipid metabolism_Homo sapiens_hsa005650.99033778
62GABAergic synapse_Homo sapiens_hsa047270.98946521
63RNA transport_Homo sapiens_hsa030130.97666070
64Dilated cardiomyopathy_Homo sapiens_hsa054140.96501318
65HTLV-I infection_Homo sapiens_hsa051660.93781369
66Propanoate metabolism_Homo sapiens_hsa006400.93640911
67Fatty acid elongation_Homo sapiens_hsa000620.91494157
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91284027
69Sphingolipid metabolism_Homo sapiens_hsa006000.90301265
70N-Glycan biosynthesis_Homo sapiens_hsa005100.85597963
71Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.85212364
72Circadian rhythm_Homo sapiens_hsa047100.84994452
73Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83976481
74Leukocyte transendothelial migration_Homo sapiens_hsa046700.83363753
75Endometrial cancer_Homo sapiens_hsa052130.81328980
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.80449080
77Amphetamine addiction_Homo sapiens_hsa050310.78559541
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76378569
79Morphine addiction_Homo sapiens_hsa050320.75559160
80Circadian entrainment_Homo sapiens_hsa047130.74730761
81Taste transduction_Homo sapiens_hsa047420.72424221
82Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71771805
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70490975
84Rap1 signaling pathway_Homo sapiens_hsa040150.69532787
85Pancreatic cancer_Homo sapiens_hsa052120.69527285
86Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69289838
87Regulation of actin cytoskeleton_Homo sapiens_hsa048100.68848548
88Pyruvate metabolism_Homo sapiens_hsa006200.68533216
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.68381914
90Phototransduction_Homo sapiens_hsa047440.67870916
91Folate biosynthesis_Homo sapiens_hsa007900.67552557
92Fatty acid metabolism_Homo sapiens_hsa012120.67256217
93Vibrio cholerae infection_Homo sapiens_hsa051100.66453811
94Ras signaling pathway_Homo sapiens_hsa040140.66279115
95Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64561447
96Estrogen signaling pathway_Homo sapiens_hsa049150.63278699
97Dorso-ventral axis formation_Homo sapiens_hsa043200.63091684
98AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.62323034
99Glycosaminoglycan degradation_Homo sapiens_hsa005310.62256922
100Insulin secretion_Homo sapiens_hsa049110.59570637
101beta-Alanine metabolism_Homo sapiens_hsa004100.58524407
102Glioma_Homo sapiens_hsa052140.58397966
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57497695
104Biosynthesis of amino acids_Homo sapiens_hsa012300.55893253
105Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.55190281
106Central carbon metabolism in cancer_Homo sapiens_hsa052300.54561898
107Nitrogen metabolism_Homo sapiens_hsa009100.54468101
108Nucleotide excision repair_Homo sapiens_hsa034200.54000935
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53468653
110Viral carcinogenesis_Homo sapiens_hsa052030.52510191
111Serotonergic synapse_Homo sapiens_hsa047260.52506759
112Homologous recombination_Homo sapiens_hsa034400.52356581
113Vitamin B6 metabolism_Homo sapiens_hsa007500.52339822
114Fatty acid biosynthesis_Homo sapiens_hsa000610.51876371
115cAMP signaling pathway_Homo sapiens_hsa040240.51640889
116Synaptic vesicle cycle_Homo sapiens_hsa047210.51324047
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.50757977
118Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50701040
119Bladder cancer_Homo sapiens_hsa052190.49924063
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49536299
121Protein export_Homo sapiens_hsa030600.49303697
122Gap junction_Homo sapiens_hsa045400.48774079
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48651228
124AMPK signaling pathway_Homo sapiens_hsa041520.48513578
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47068704
126FoxO signaling pathway_Homo sapiens_hsa040680.46075821
127Long-term depression_Homo sapiens_hsa047300.45996375
128Cholinergic synapse_Homo sapiens_hsa047250.45822007
129Amoebiasis_Homo sapiens_hsa051460.45498767
130Arachidonic acid metabolism_Homo sapiens_hsa005900.44573896
131Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43661895
132Alcoholism_Homo sapiens_hsa050340.43050325
133RNA polymerase_Homo sapiens_hsa030200.42426883
134Thyroid cancer_Homo sapiens_hsa052160.40555360
135Oocyte meiosis_Homo sapiens_hsa041140.40526631
136Arginine and proline metabolism_Homo sapiens_hsa003300.40205024
137Choline metabolism in cancer_Homo sapiens_hsa052310.39124715
138Neurotrophin signaling pathway_Homo sapiens_hsa047220.33419301
139Renin-angiotensin system_Homo sapiens_hsa046140.31563883
140Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.30665295
141Sphingolipid signaling pathway_Homo sapiens_hsa040710.30619133
142Linoleic acid metabolism_Homo sapiens_hsa005910.30176933

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