LCA5L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1multicellular organism reproduction (GO:0032504)9.81824015
2epithelial cilium movement (GO:0003351)9.80126761
3acrosome assembly (GO:0001675)9.66715786
4acrosome reaction (GO:0007340)9.57444548
5sperm-egg recognition (GO:0035036)9.56078514
6piRNA metabolic process (GO:0034587)9.48894450
7motile cilium assembly (GO:0044458)9.17423801
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.98167155
9cilium movement (GO:0003341)8.90726897
10plasma membrane fusion (GO:0045026)8.69787486
11cell wall macromolecule metabolic process (GO:0044036)8.66654429
12cell wall macromolecule catabolic process (GO:0016998)8.66654429
13binding of sperm to zona pellucida (GO:0007339)8.63367951
14cell-cell recognition (GO:0009988)8.50883854
15male meiosis (GO:0007140)8.31552652
16spermatid development (GO:0007286)8.09053847
17reproduction (GO:0000003)7.71888903
18regulation of cilium movement (GO:0003352)7.62169298
19synaptonemal complex organization (GO:0070193)7.19538872
20synaptonemal complex assembly (GO:0007130)6.79680923
21single fertilization (GO:0007338)6.73842664
22DNA methylation involved in gamete generation (GO:0043046)6.51924380
23sperm capacitation (GO:0048240)6.36428565
24ventricular system development (GO:0021591)5.74933028
25male meiosis I (GO:0007141)5.74661501
26fertilization (GO:0009566)5.64289578
27microtubule depolymerization (GO:0007019)5.58073509
28protein localization to cilium (GO:0061512)5.46870268
29spermatogenesis (GO:0007283)5.37661617
30male gamete generation (GO:0048232)5.35847955
31negative regulation of inclusion body assembly (GO:0090084)5.18662429
32chromosome organization involved in meiosis (GO:0070192)5.06065698
33gamete generation (GO:0007276)4.95210883
34germ cell development (GO:0007281)4.80211193
35cellular process involved in reproduction in multicellular organism (GO:0022412)4.72657790
36meiotic nuclear division (GO:0007126)4.66995597
37intraciliary transport (GO:0042073)4.60456488
38meiosis I (GO:0007127)4.47886883
39microtubule severing (GO:0051013)4.45422774
40organic cation transport (GO:0015695)4.44218618
41meiotic cell cycle (GO:0051321)4.39970620
42calcium ion-dependent exocytosis (GO:0017156)4.38591562
43seminiferous tubule development (GO:0072520)4.35593746
44cell recognition (GO:0008037)4.25084584
45axoneme assembly (GO:0035082)4.20310924
46regulation of inclusion body assembly (GO:0090083)4.13218495
47regulation of microtubule-based movement (GO:0060632)4.07720302
48left/right pattern formation (GO:0060972)4.02590618
49monoubiquitinated protein deubiquitination (GO:0035520)3.97176667
50centriole assembly (GO:0098534)3.92845553
51multicellular organismal reproductive process (GO:0048609)3.89598572
52retinal cone cell development (GO:0046549)3.87682936
53protein polyglutamylation (GO:0018095)3.86837107
54cilium organization (GO:0044782)3.84325700
55cilium assembly (GO:0042384)3.73090203
56centriole replication (GO:0007099)3.69367928
57genitalia morphogenesis (GO:0035112)3.65045087
58resolution of meiotic recombination intermediates (GO:0000712)3.40324294
59regulation of meiosis I (GO:0060631)3.33662952
60cellular component assembly involved in morphogenesis (GO:0010927)3.32011610
61microtubule-based movement (GO:0007018)3.31624828
62microtubule bundle formation (GO:0001578)3.31462949
63gamma-aminobutyric acid transport (GO:0015812)3.29266639
64synapsis (GO:0007129)3.29190707
65cilium morphogenesis (GO:0060271)3.26176056
66L-fucose catabolic process (GO:0042355)3.23934553
67fucose catabolic process (GO:0019317)3.23934553
68L-fucose metabolic process (GO:0042354)3.23934553
69multicellular organismal development (GO:0007275)3.21934294
70meiotic cell cycle process (GO:1903046)3.21258862
71regulation of spindle checkpoint (GO:0090231)3.20439757
72gene silencing by RNA (GO:0031047)3.14973160
73spermatid nucleus differentiation (GO:0007289)3.11969490
74lactate metabolic process (GO:0006089)3.05608237
75detection of light stimulus involved in sensory perception (GO:0050962)3.03822551
76detection of light stimulus involved in visual perception (GO:0050908)3.03822551
77regulation of centriole replication (GO:0046599)3.03229035
78positive regulation of meiosis (GO:0045836)3.02815677
79reciprocal meiotic recombination (GO:0007131)2.95787469
80reciprocal DNA recombination (GO:0035825)2.95787469
81photoreceptor cell maintenance (GO:0045494)2.93861888
82indolalkylamine catabolic process (GO:0046218)2.90510633
83tryptophan catabolic process (GO:0006569)2.90510633
84indole-containing compound catabolic process (GO:0042436)2.90510633
85nucleoside diphosphate phosphorylation (GO:0006165)2.90097979
86left/right axis specification (GO:0070986)2.85995801
87neuronal action potential (GO:0019228)2.84731060
88protein K11-linked deubiquitination (GO:0035871)2.83403112
89positive regulation of meiotic cell cycle (GO:0051446)2.82527059
90microtubule polymerization or depolymerization (GO:0031109)2.80873772
91cornea development in camera-type eye (GO:0061303)2.78514227
92RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.76756528
93tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.76756528
94mitotic sister chromatid cohesion (GO:0007064)2.76678861
95behavioral response to nicotine (GO:0035095)2.75847058
96water-soluble vitamin biosynthetic process (GO:0042364)2.75152045
97cellular ketone body metabolic process (GO:0046950)2.74844374
98nuclear pore complex assembly (GO:0051292)2.71617718
99neural tube formation (GO:0001841)2.71045363
100polyol catabolic process (GO:0046174)2.70727198
101nonmotile primary cilium assembly (GO:0035058)2.68559452
102somite rostral/caudal axis specification (GO:0032525)2.65892125
103somite development (GO:0061053)2.65471675
104GTP biosynthetic process (GO:0006183)2.63652723
105indolalkylamine metabolic process (GO:0006586)2.61803024
106determination of left/right symmetry (GO:0007368)2.60462819
107DNA methylation (GO:0006306)2.59776211
108DNA alkylation (GO:0006305)2.59776211
109negative regulation of telomere maintenance (GO:0032205)2.56085498
110smoothened signaling pathway (GO:0007224)2.55512671
111sister chromatid cohesion (GO:0007062)2.54919476
112protein localization to Golgi apparatus (GO:0034067)2.54839540
113meiotic chromosome segregation (GO:0045132)2.53034522
114photoreceptor cell development (GO:0042461)2.52699057
115detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.52387037
116phosphatidylethanolamine metabolic process (GO:0046337)2.51767070
117glycerol ether metabolic process (GO:0006662)2.51563058
118regulation of action potential (GO:0098900)2.51539204
119sulfate transmembrane transport (GO:1902358)2.50752939
120cell projection assembly (GO:0030031)2.50499729
121determination of bilateral symmetry (GO:0009855)2.50298821
122negative regulation of organelle assembly (GO:1902116)2.49553936
123ketone body metabolic process (GO:1902224)2.48953326
124establishment of protein localization to Golgi (GO:0072600)2.48729147
125DNA packaging (GO:0006323)2.48258918
126phosphatidylethanolamine biosynthetic process (GO:0006646)2.47779570
127RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.46851233
128behavioral response to ethanol (GO:0048149)2.45883044
129reflex (GO:0060004)2.44666012
130pore complex assembly (GO:0046931)2.44555191
131specification of symmetry (GO:0009799)2.42795421
132response to pheromone (GO:0019236)2.41874863
133ether metabolic process (GO:0018904)2.39696817
134calcium ion import (GO:0070509)2.39600335
135nucleus organization (GO:0006997)2.39335158
136negative regulation of skeletal muscle tissue development (GO:0048642)2.37226788
137organelle assembly (GO:0070925)2.35078772
138protein refolding (GO:0042026)2.31282340
139cellular response to gamma radiation (GO:0071480)2.30279317
140regulation of protein polyubiquitination (GO:1902914)2.29203983
141rRNA catabolic process (GO:0016075)2.28060361
142daunorubicin metabolic process (GO:0044597)2.27389855
143doxorubicin metabolic process (GO:0044598)2.27389855
144cilium or flagellum-dependent cell motility (GO:0001539)14.7394008
145fusion of sperm to egg plasma membrane (GO:0007342)11.3755733
146axonemal dynein complex assembly (GO:0070286)10.8578075
147sperm motility (GO:0030317)10.8037922

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse7.11081523
2EZH2_22144423_ChIP-Seq_EOC_Human5.99132550
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.47319381
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.21211164
5FLI1_27457419_Chip-Seq_LIVER_Mouse2.69276576
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.65174262
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.59703389
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.58052918
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.53884193
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.20411335
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.13181503
12EWS_26573619_Chip-Seq_HEK293_Human2.12998503
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08976728
14GBX2_23144817_ChIP-Seq_PC3_Human2.01861709
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.00479593
16VDR_22108803_ChIP-Seq_LS180_Human1.96312483
17NFE2_27457419_Chip-Seq_LIVER_Mouse1.93686526
18SUZ12_27294783_Chip-Seq_NPCs_Mouse1.92265395
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.91275364
20PCGF2_27294783_Chip-Seq_NPCs_Mouse1.90585316
21TAF15_26573619_Chip-Seq_HEK293_Human1.86252304
22PIAS1_25552417_ChIP-Seq_VCAP_Human1.86090047
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.85826679
24TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.78285556
25ZNF274_21170338_ChIP-Seq_K562_Hela1.77675221
26BCAT_22108803_ChIP-Seq_LS180_Human1.69092372
27RNF2_27304074_Chip-Seq_NSC_Mouse1.67714278
28NANOG_18555785_Chip-Seq_ESCs_Mouse1.67632001
29AR_25329375_ChIP-Seq_VCAP_Human1.66953853
30GATA1_26923725_Chip-Seq_HPCs_Mouse1.62693873
31EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.62001033
32EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.61390517
33TAL1_26923725_Chip-Seq_HPCs_Mouse1.59784829
34P53_22387025_ChIP-Seq_ESCs_Mouse1.55672553
35TOP2B_26459242_ChIP-Seq_MCF-7_Human1.55135398
36KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.53822165
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53254192
38TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52826893
39POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.52826893
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.51506113
41ELK4_26923725_Chip-Seq_MESODERM_Mouse1.51038683
42NR3C1_21868756_ChIP-Seq_MCF10A_Human1.50858833
43HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.48495872
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.48298327
45SUZ12_18555785_Chip-Seq_ESCs_Mouse1.47853352
46STAT3_18555785_Chip-Seq_ESCs_Mouse1.47818264
47OCT4_18555785_Chip-Seq_ESCs_Mouse1.44129083
48P300_18555785_Chip-Seq_ESCs_Mouse1.43953839
49EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.43227946
50E2F1_18555785_Chip-Seq_ESCs_Mouse1.43216726
51CMYC_18555785_Chip-Seq_ESCs_Mouse1.42777374
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42776959
53REST_21632747_ChIP-Seq_MESCs_Mouse1.41912390
54KDM2B_26808549_Chip-Seq_REH_Human1.41326305
55FOXA1_25329375_ChIP-Seq_VCAP_Human1.41079379
56FOXA1_27270436_Chip-Seq_PROSTATE_Human1.41079379
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40711793
58CBP_20019798_ChIP-Seq_JUKART_Human1.40711793
59RUNX2_22187159_ChIP-Seq_PCA_Human1.39789926
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39722267
61FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.37741476
62STAT1_17558387_ChIP-Seq_HELA_Human1.37308635
63MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36814925
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.35499752
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.34719543
66KLF5_20875108_ChIP-Seq_MESCs_Mouse1.34413582
67TCF4_22108803_ChIP-Seq_LS180_Human1.33478162
68FOXA1_21572438_ChIP-Seq_LNCaP_Human1.33407924
69RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33230070
70SMAD4_21741376_ChIP-Seq_EPCs_Human1.33157698
71KLF4_18555785_Chip-Seq_ESCs_Mouse1.30664296
72RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.30296844
73CRX_20693478_ChIP-Seq_RETINA_Mouse1.30289957
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.29827489
75KAP1_22055183_ChIP-Seq_ESCs_Mouse1.29017737
76ER_23166858_ChIP-Seq_MCF-7_Human1.28849902
77NANOG_19829295_ChIP-Seq_ESCs_Human1.28778537
78SOX2_19829295_ChIP-Seq_ESCs_Human1.28778537
79AR_21572438_ChIP-Seq_LNCaP_Human1.28703314
80RUNX1_27457419_Chip-Seq_LIVER_Mouse1.28252751
81ESRRB_18555785_Chip-Seq_ESCs_Mouse1.28030599
82SOX2_18555785_Chip-Seq_ESCs_Mouse1.27666491
83TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.27476474
84CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.27393925
85TP53_22573176_ChIP-Seq_HFKS_Human1.26949433
86IRF1_19129219_ChIP-ChIP_H3396_Human1.26879164
87NMYC_18555785_Chip-Seq_ESCs_Mouse1.26138320
88PU1_27457419_Chip-Seq_LIVER_Mouse1.24821694
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.24403006
90CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.23941772
91SMAD4_21799915_ChIP-Seq_A2780_Human1.23849753
92GABP_17652178_ChIP-ChIP_JURKAT_Human1.23328603
93MYC_18940864_ChIP-ChIP_HL60_Human1.22200636
94WDR5_24793694_ChIP-Seq_LNCAP_Human1.22069785
95ZFX_18555785_Chip-Seq_ESCs_Mouse1.21303456
96TCF4_23295773_ChIP-Seq_U87_Human1.21165950
97GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20132111
98OCT4_21477851_ChIP-Seq_ESCs_Mouse1.19568073
99AUTS2_25519132_ChIP-Seq_293T-REX_Human1.19113699
100E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.18611428
101RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18024516
102PRDM14_20953172_ChIP-Seq_ESCs_Human1.17506709
103CTCF_18555785_Chip-Seq_ESCs_Mouse1.17008275
104CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15858006
105NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.15463076
106* FUS_26573619_Chip-Seq_HEK293_Human1.15248020
107SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15081404
108HOXB7_26014856_ChIP-Seq_BT474_Human1.13763330
109AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12800230
110FOXM1_26456572_ChIP-Seq_MCF-7_Human1.12705036
111NCOR_22424771_ChIP-Seq_293T_Human1.12394191
112P300_19829295_ChIP-Seq_ESCs_Human1.12306271
113BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12014040
114ETV2_25802403_ChIP-Seq_MESCs_Mouse1.11295274
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11179603
116CDX2_22108803_ChIP-Seq_LS180_Human1.10065727
117GF1_26923725_Chip-Seq_HPCs_Mouse1.08331971
118CTBP1_25329375_ChIP-Seq_LNCAP_Human1.08180751
119AR_20517297_ChIP-Seq_VCAP_Human1.07358970
120SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06942182
121CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06256517
122TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05425024
123IGF1R_20145208_ChIP-Seq_DFB_Human1.05284036
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04710004
125GATA3_21878914_ChIP-Seq_MCF-7_Human1.04245418
126SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03924397
127FLI1_21867929_ChIP-Seq_TH2_Mouse1.02615439
128SMAD3_21741376_ChIP-Seq_EPCs_Human1.02311003
129ARNT_22903824_ChIP-Seq_MCF-7_Human1.02019366
130STAT3_23295773_ChIP-Seq_U87_Human1.00184724
131ETV1_20927104_ChIP-Seq_GIST48_Human0.99805007
132MYC_19829295_ChIP-Seq_ESCs_Human0.99214387
133DROSHA_22980978_ChIP-Seq_HELA_Human0.98965317
134PHF8_20622853_ChIP-Seq_HELA_Human0.98412644
135SOX9_26525672_Chip-Seq_HEART_Mouse0.97873415
136LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96992126
137UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96410375
138EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.96384137
139CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95426265
140SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.94784940
141RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.94093954
142CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93110304
143* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.92906813
144TBL1_22424771_ChIP-Seq_293T_Human0.92341367
145SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.92050577
146RUNX1_26923725_Chip-Seq_HPCs_Mouse0.92004743
147GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.91931977

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.05773847
2MP0008877_abnormal_DNA_methylation4.71671507
3MP0001929_abnormal_gametogenesis4.57835378
4MP0002210_abnormal_sex_determination3.45715464
5MP0002653_abnormal_ependyma_morphology2.73081313
6MP0001145_abnormal_male_reproductive2.68382703
7MP0002161_abnormal_fertility/fecundity2.65343650
8MP0000653_abnormal_sex_gland2.43739939
9MP0003195_calcinosis2.24160888
10MP0001984_abnormal_olfaction2.16514065
11MP0008875_abnormal_xenobiotic_pharmacok2.07335588
12MP0002160_abnormal_reproductive_system2.01160301
13MP0005410_abnormal_fertilization12.0816894
14MP0000383_abnormal_hair_follicle1.91765790
15MP0008057_abnormal_DNA_replication1.88870375
16MP0009046_muscle_twitch1.85407394
17MP0005646_abnormal_pituitary_gland1.84701563
18MP0003878_abnormal_ear_physiology1.76770082
19MP0005377_hearing/vestibular/ear_phenot1.76770082
20MP0002102_abnormal_ear_morphology1.76017606
21MP0002837_dystrophic_cardiac_calcinosis1.75218456
22MP0003718_maternal_effect1.71467341
23MP0008058_abnormal_DNA_repair1.71055838
24MP0009780_abnormal_chondrocyte_physiolo1.68143403
25MP0006072_abnormal_retinal_apoptosis1.60110049
26MP0005645_abnormal_hypothalamus_physiol1.58317759
27MP0000566_synostosis1.58117527
28MP0006292_abnormal_olfactory_placode1.57128884
29MP0004043_abnormal_pH_regulation1.56108830
30MP0008995_early_reproductive_senescence1.55797054
31MP0003646_muscle_fatigue1.54862967
32MP0000427_abnormal_hair_cycle1.52130773
33MP0005623_abnormal_meninges_morphology1.51927552
34MP0001188_hyperpigmentation1.44686323
35MP0002822_catalepsy1.44515389
36MP0004885_abnormal_endolymph1.37406828
37MP0008789_abnormal_olfactory_epithelium1.37196503
38MP0000569_abnormal_digit_pigmentation1.36918093
39MP0002234_abnormal_pharynx_morphology1.36567030
40MP0000015_abnormal_ear_pigmentation1.35437869
41MP0008872_abnormal_physiological_respon1.34004109
42MP0000372_irregular_coat_pigmentation1.33629538
43MP0001986_abnormal_taste_sensitivity1.30649562
44MP0010678_abnormal_skin_adnexa1.29111709
45MP0005389_reproductive_system_phenotype1.22297722
46MP0004142_abnormal_muscle_tone1.16347688
47MP0001970_abnormal_pain_threshold1.16008321
48MP0004145_abnormal_muscle_electrophysio1.14408560
49MP0005423_abnormal_somatic_nervous1.13775224
50MP0003787_abnormal_imprinting1.12672459
51MP0010094_abnormal_chromosome_stability1.10927681
52MP0003890_abnormal_embryonic-extraembry1.10537540
53MP0002138_abnormal_hepatobiliary_system1.09874981
54MP0001486_abnormal_startle_reflex1.09315696
55MP0002733_abnormal_thermal_nociception1.09201574
56MP0006276_abnormal_autonomic_nervous1.04117994
57MP0002282_abnormal_trachea_morphology1.04095922
58MP0005647_abnormal_sex_gland1.02566815
59MP0002064_seizures1.01522761
60MP0004215_abnormal_myocardial_fiber1.00242397
61MP0002736_abnormal_nociception_after0.99161873
62MP0003880_abnormal_central_pattern0.98973353
63MP0003786_premature_aging0.96748920
64MP0009697_abnormal_copulation0.96533014
65MP0003283_abnormal_digestive_organ0.96376465
66MP0005174_abnormal_tail_pigmentation0.95944912
67MP0003937_abnormal_limbs/digits/tail_de0.95721395
68MP0005551_abnormal_eye_electrophysiolog0.93620520
69MP0005670_abnormal_white_adipose0.91546288
70MP0002163_abnormal_gland_morphology0.90317797
71MP0003879_abnormal_hair_cell0.90017371
72MP0005195_abnormal_posterior_eye0.89337978
73MP0002277_abnormal_respiratory_mucosa0.87733596
74MP0004134_abnormal_chest_morphology0.87211792
75MP0001764_abnormal_homeostasis0.86086539
76MP0001968_abnormal_touch/_nociception0.85274440
77MP0005394_taste/olfaction_phenotype0.85214631
78MP0005499_abnormal_olfactory_system0.85214631
79MP0002132_abnormal_respiratory_system0.84519258
80MP0004147_increased_porphyrin_level0.84194668
81MP0002572_abnormal_emotion/affect_behav0.82443077
82MP0004924_abnormal_behavior0.81565455
83MP0005386_behavior/neurological_phenoty0.81565455
84MP0002229_neurodegeneration0.81237361
85MP0005395_other_phenotype0.81032757
86MP0004742_abnormal_vestibular_system0.81019948
87MP0001501_abnormal_sleep_pattern0.79551760
88MP0001119_abnormal_female_reproductive0.79337496
89MP0001324_abnormal_eye_pigmentation0.77039329
90MP0002638_abnormal_pupillary_reflex0.76959990
91MP0008007_abnormal_cellular_replicative0.76314885
92MP0000631_abnormal_neuroendocrine_gland0.73797159
93MP0002557_abnormal_social/conspecific_i0.71470416
94MP0008004_abnormal_stomach_pH0.71311993
95MP0001293_anophthalmia0.71021421
96MP0005253_abnormal_eye_physiology0.70581969
97MP0002735_abnormal_chemical_nociception0.69676718
98MP0001529_abnormal_vocalization0.66626083
99MP0005075_abnormal_melanosome_morpholog0.63174295
100MP0009745_abnormal_behavioral_response0.62870286
101MP0002876_abnormal_thyroid_physiology0.62360057
102MP0002928_abnormal_bile_duct0.60734151
103MP0003950_abnormal_plasma_membrane0.60617989
104MP0002272_abnormal_nervous_system0.60388165
105MP0001440_abnormal_grooming_behavior0.60303556
106MP0005409_darkened_coat_color0.60288448
107MP0004808_abnormal_hematopoietic_stem0.59865415
108MP0001963_abnormal_hearing_physiology0.59300309
109MP0001765_abnormal_ion_homeostasis0.58008586
110MP0005171_absent_coat_pigmentation0.55893443
111MP0000778_abnormal_nervous_system0.55863087
112MP0002067_abnormal_sensory_capabilities0.54029812
113MP0003136_yellow_coat_color0.53985917
114MP0003699_abnormal_female_reproductive0.52982319
115MP0000026_abnormal_inner_ear0.52952022
116MP0005391_vision/eye_phenotype0.49665142
117MP0001485_abnormal_pinna_reflex0.49498629
118MP0003011_delayed_dark_adaptation0.49221173
119MP0003635_abnormal_synaptic_transmissio0.49179415
120MP0005379_endocrine/exocrine_gland_phen0.48399309
121MP0002938_white_spotting0.48224985
122MP0001502_abnormal_circadian_rhythm0.47945434
123MP0002177_abnormal_outer_ear0.47720742
124MP0002095_abnormal_skin_pigmentation0.47486978
125MP0005257_abnormal_intraocular_pressure0.47349599
126MP0002063_abnormal_learning/memory/cond0.46779562
127MP0002184_abnormal_innervation0.46433073
128MP0009250_abnormal_appendicular_skeleto0.45473366
129MP0001919_abnormal_reproductive_system0.45089150
130MP0002116_abnormal_craniofacial_bone0.43922875
131MP0003693_abnormal_embryo_hatching0.43646340
132MP0002152_abnormal_brain_morphology0.43294637
133MP0000049_abnormal_middle_ear0.42476617
134MP0002734_abnormal_mechanical_nocicepti0.42108707
135MP0002752_abnormal_somatic_nervous0.41850245
136MP0004133_heterotaxia0.41059156

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.99863812
2Abnormal respiratory motile cilium morphology (HP:0005938)8.44072375
3Abnormal respiratory epithelium morphology (HP:0012253)8.44072375
4Abnormal ciliary motility (HP:0012262)7.71955492
5Rhinitis (HP:0012384)7.56507835
6Chronic bronchitis (HP:0004469)5.99023610
7Infertility (HP:0000789)5.20788589
8Nasal polyposis (HP:0100582)4.89952729
9Nephronophthisis (HP:0000090)4.89537980
10Bronchiectasis (HP:0002110)4.34497432
11Abnormality of the nasal mucosa (HP:0000433)3.89358413
12Abnormality of the renal medulla (HP:0100957)3.83515600
13Bronchitis (HP:0012387)3.64160671
14Molar tooth sign on MRI (HP:0002419)3.42692864
15Abnormality of midbrain morphology (HP:0002418)3.42692864
16Tubulointerstitial nephritis (HP:0001970)3.30367599
17Medial flaring of the eyebrow (HP:0010747)3.04741830
18Recurrent sinusitis (HP:0011108)3.01333848
19Gonadotropin excess (HP:0000837)2.83055310
20Abnormal spermatogenesis (HP:0008669)2.81310086
21Congenital stationary night blindness (HP:0007642)2.76646422
22Postaxial foot polydactyly (HP:0001830)2.74393879
23Recurrent otitis media (HP:0000403)2.73604360
24Pancreatic fibrosis (HP:0100732)2.71320422
25Fibular hypoplasia (HP:0003038)2.61683316
26Sclerocornea (HP:0000647)2.61559954
27Congenital hepatic fibrosis (HP:0002612)2.44307201
28Abnormal rod and cone electroretinograms (HP:0008323)2.42329667
29True hermaphroditism (HP:0010459)2.42216648
30Tubulointerstitial abnormality (HP:0001969)2.36753545
31Tubular atrophy (HP:0000092)2.35572991
32Male infertility (HP:0003251)2.31999341
33Attenuation of retinal blood vessels (HP:0007843)2.31300319
34Vaginal atresia (HP:0000148)2.29179166
35Abolished electroretinogram (ERG) (HP:0000550)2.26038845
36Hypoplasia of the capital femoral epiphysis (HP:0003090)2.25855714
37Furrowed tongue (HP:0000221)2.19403550
38Renal dysplasia (HP:0000110)2.18555867
39Impulsivity (HP:0100710)2.17876442
40Chronic hepatic failure (HP:0100626)2.14024731
41Bile duct proliferation (HP:0001408)2.12563072
42Abnormal biliary tract physiology (HP:0012439)2.12563072
43Hypothermia (HP:0002045)2.09129494
44Postaxial hand polydactyly (HP:0001162)2.08758995
45Recurrent bronchitis (HP:0002837)2.07585379
46Azoospermia (HP:0000027)2.05959433
47Absent rod-and cone-mediated responses on ERG (HP:0007688)2.03269051
48Chronic sinusitis (HP:0011109)2.02476033
49Median cleft lip (HP:0000161)2.02100903
50Bony spicule pigmentary retinopathy (HP:0007737)2.01878382
51Stage 5 chronic kidney disease (HP:0003774)2.00949878
52Supernumerary spleens (HP:0009799)2.00741412
53Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.2443912
54Dynein arm defect of respiratory motile cilia (HP:0012255)11.3813876
55Absent/shortened dynein arms (HP:0200106)11.3813876
56Hyperventilation (HP:0002883)1.98741267
57Abnormality of the lower motor neuron (HP:0002366)1.96467109
58Cystic liver disease (HP:0006706)1.95085925
59Pancreatic cysts (HP:0001737)1.94115718
60Abnormality of the renal cortex (HP:0011035)1.93760900
61Optic nerve hypoplasia (HP:0000609)1.93655341
62Oculomotor apraxia (HP:0000657)1.93344576
63Congenital primary aphakia (HP:0007707)1.92677390
64Aplasia/Hypoplasia of the tongue (HP:0010295)1.92656552
65Oligodactyly (hands) (HP:0001180)1.92600182
66Facial cleft (HP:0002006)1.90184781
67Aplasia/Hypoplasia of the fibula (HP:0006492)1.89831857
68Gait imbalance (HP:0002141)1.89205985
69Hyperglycinemia (HP:0002154)1.88364222
70Inability to walk (HP:0002540)1.87778441
71Impaired proprioception (HP:0010831)1.85278569
72Abnormality of the dental root (HP:0006486)1.85092769
73Taurodontia (HP:0000679)1.85092769
74Abnormality of permanent molar morphology (HP:0011071)1.85092769
75Large for gestational age (HP:0001520)1.84724721
76Type II lissencephaly (HP:0007260)1.84458829
77Decreased central vision (HP:0007663)1.84448730
78Polyuria (HP:0000103)1.84276909
79Dyschromatopsia (HP:0007641)1.82868050
80Nephrogenic diabetes insipidus (HP:0009806)1.82258112
81Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.80748849
82Absent epiphyses (HP:0010577)1.80748849
83Abnormality of molar (HP:0011077)1.79613088
84Abnormality of molar morphology (HP:0011070)1.79613088
85Broad-based gait (HP:0002136)1.78627982
86Absent frontal sinuses (HP:0002688)1.76550675
87Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75600534
88Renal cortical cysts (HP:0000803)1.75155728
89Decreased circulating renin level (HP:0003351)1.72936648
90Aplasia/Hypoplasia of the lens (HP:0008063)1.70280353
91Preaxial hand polydactyly (HP:0001177)1.70010418
92Aganglionic megacolon (HP:0002251)1.69707942
93Abnormal drinking behavior (HP:0030082)1.69519393
94Polydipsia (HP:0001959)1.69519393
95Hyperglycinuria (HP:0003108)1.68348658
96Abnormality of macular pigmentation (HP:0008002)1.67448572
97Gaze-evoked nystagmus (HP:0000640)1.67124122
98Progressive inability to walk (HP:0002505)1.66725354
99Abnormality of the dental pulp (HP:0006479)1.66203638
100Atonic seizures (HP:0010819)1.65001288
101Congenital, generalized hypertrichosis (HP:0004540)1.64127024
102Short tibia (HP:0005736)1.63437613
103Ectopic kidney (HP:0000086)1.63394715
104Narrow forehead (HP:0000341)1.63145150
105Aplasia/Hypoplasia of the spleen (HP:0010451)1.61499212
106Anophthalmia (HP:0000528)1.60860261
107Methylmalonic acidemia (HP:0002912)1.60456811
108Retinitis pigmentosa (HP:0000510)1.60357932
109Nephropathy (HP:0000112)1.60229113
110Multicystic kidney dysplasia (HP:0000003)1.60033798
111Absent eyebrow (HP:0002223)1.59712889
112Microglossia (HP:0000171)1.58754646
113Amyotrophic lateral sclerosis (HP:0007354)1.58677726
114Hyperkalemia (HP:0002153)1.58267665
115Chromosomal breakage induced by crosslinking agents (HP:0003221)1.57979304
116Febrile seizures (HP:0002373)1.57741352
117Aplasia/Hypoplasia of the uvula (HP:0010293)1.57438763
118Asplenia (HP:0001746)1.55851074
119Short ribs (HP:0000773)1.55648188
120Oligohydramnios (HP:0001562)1.53905266
121Acute encephalopathy (HP:0006846)1.53228614
122Aplasia/Hypoplasia of the tibia (HP:0005772)1.51576030
123Large eyes (HP:0001090)1.51190378
124Tubulointerstitial fibrosis (HP:0005576)1.50931957
125Short thorax (HP:0010306)1.50805763
126Abnormality of the labia minora (HP:0012880)1.49985018
127Bell-shaped thorax (HP:0001591)1.49724611
128Pendular nystagmus (HP:0012043)1.49462968
129Degeneration of anterior horn cells (HP:0002398)1.49056670
130Abnormality of the anterior horn cell (HP:0006802)1.49056670
131Upper motor neuron abnormality (HP:0002127)1.48724919
132Abnormality of glycine metabolism (HP:0010895)1.48606484
133Retinal dysplasia (HP:0007973)1.48361787
13411 pairs of ribs (HP:0000878)1.45467550
135Occipital encephalocele (HP:0002085)1.43922215
136Chromsome breakage (HP:0040012)1.41086398
137J-shaped sella turcica (HP:0002680)1.40871422
138Poor coordination (HP:0002370)1.39860357
139Short femoral neck (HP:0100864)1.39512942
140Male pseudohermaphroditism (HP:0000037)1.37828324
141Nephroblastoma (Wilms tumor) (HP:0002667)1.37724555
142Astigmatism (HP:0000483)1.34972511
143Genital tract atresia (HP:0001827)1.33757921
144Anencephaly (HP:0002323)1.31927357

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.47486857
2PDK47.47486857
3PDK24.90042508
4FRK4.73986292
5TESK13.58326385
6MAP4K23.27322327
7PRKD33.20079248
8ACVR1B2.86221977
9ICK2.41752023
10PTK2B2.22848423
11PNCK2.21861788
12TRIM282.19891297
13SIK32.15179681
14MST42.05691937
15TLK11.95159674
16BMPR1B1.88664174
17TNIK1.79325771
18WNK41.79006640
19STK391.72296805
20MUSK1.70901920
21TAOK31.64373573
22MAPKAPK31.59785514
23OXSR11.58879196
24CASK1.56153876
25CCNB11.50997157
26MAPK151.48023849
27STK381.38280571
28SRPK11.35636634
29PLK41.32405738
30NEK21.32162237
31MAP2K71.26297711
32PRPF4B1.25661729
33WNK11.21842223
34CSNK1G11.10559520
35NME11.05334398
36CDC71.02228421
37PHKG20.93571950
38PHKG10.93571950
39PRKCE0.93126155
40STK30.93074426
41CDK30.91960929
42TGFBR10.91870055
43YES10.89521022
44BCR0.86849064
45PINK10.85897779
46ATR0.84673862
47CSNK1G20.83250863
48ADRBK10.83109301
49PASK0.83011481
50CDK80.82219391
51DYRK20.81846626
52CHEK20.81821117
53PAK30.80482791
54NEK60.79160755
55IRAK10.78671942
56SIK20.76756924
57ZAK0.76695956
58NTRK20.75699472
59SGK20.75026975
60CSNK1G30.73625901
61TXK0.71602560
62MAPK130.70895109
63AKT30.68769664
64MAP3K120.68140557
65BRSK20.67331644
66WNK30.66822980
67OBSCN0.64206607
68PRKCI0.63761023
69CDK120.62859986
70DYRK1B0.62806797
71STK38L0.62481083
72CAMK1G0.62208611
73DYRK30.61551576
74PDK10.59480577
75BCKDK0.58971514
76FER0.57887677
77ADRBK20.55202710
78TTK0.53749235
79BRAF0.52653073
80FGFR20.50940431
81MAP2K40.50654247
82CHEK10.50488678
83CDK190.50397914
84CSNK1A1L0.49318598
85CAMK2A0.49284427
86INSRR0.46717269
87VRK10.46038217
88EIF2AK20.45388374
89ATM0.44211409
90CSNK1A10.43020721
91PLK30.42894294
92RPS6KB10.42281353
93GRK10.41262268
94RIPK40.41178914
95TNK20.40270687
96MAP3K40.39998834
97NLK0.39959407
98PRKACA0.39592519
99LATS10.39591230
100CAMK10.39516927
101WEE10.39306407
102MARK30.39034805
103MAP2K60.38893205
104EIF2AK30.37821279
105MKNK10.37150740
106STK160.37016528
107TIE10.34617139
108MARK20.34237162
109RPS6KA50.34163094
110GRK70.33624458
111CSNK1E0.31419970
112MINK10.31013015
113MAP3K20.30158548
114BMPR20.29806761
115CSNK1D0.29734368
116SGK2230.29708316
117SGK4940.29708316
118STK240.29694682
119PRKACB0.29605275
120NUAK10.29415420
121PRKCG0.29096477
122PLK20.29080674
123PRKAA10.28042009
124BRD40.27527290
125MAP3K140.27420242
126SGK30.26116928
127CAMKK20.24502292
128MAPKAPK50.22517844
129ERBB30.22144252
130IRAK20.21429637
131PRKG10.21010872
132MKNK20.20781161
133NTRK30.20379102
134PLK10.20252985
135DYRK1A0.20115130
136TEC0.19788027
137BRSK10.18077255
138CDK70.15970793
139PRKD20.15847152
140GSK3B0.15346408
141PRKCQ0.14565838
142EPHA40.13669317
143MARK10.13280430
144PRKAA20.12863318

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.69344999
2Basal transcription factors_Homo sapiens_hsa030223.52079881
3Fanconi anemia pathway_Homo sapiens_hsa034603.48164287
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.43681856
5Fatty acid biosynthesis_Homo sapiens_hsa000612.26318485
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.21513343
7Nitrogen metabolism_Homo sapiens_hsa009102.08070954
8Butanoate metabolism_Homo sapiens_hsa006502.01458696
9Dorso-ventral axis formation_Homo sapiens_hsa043201.98794952
10Caffeine metabolism_Homo sapiens_hsa002321.95764906
11Glucagon signaling pathway_Homo sapiens_hsa049221.93911222
12Pyruvate metabolism_Homo sapiens_hsa006201.91502901
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.91296610
14Nicotine addiction_Homo sapiens_hsa050331.90442452
15Protein export_Homo sapiens_hsa030601.86757996
16Chemical carcinogenesis_Homo sapiens_hsa052041.83049947
17Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.78875723
18Maturity onset diabetes of the young_Homo sapiens_hsa049501.78597217
19Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.74181203
20Amphetamine addiction_Homo sapiens_hsa050311.73813836
21Linoleic acid metabolism_Homo sapiens_hsa005911.69608018
22Huntingtons disease_Homo sapiens_hsa050161.69160480
23mRNA surveillance pathway_Homo sapiens_hsa030151.68590097
24Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.66937292
25Olfactory transduction_Homo sapiens_hsa047401.65602087
26Homologous recombination_Homo sapiens_hsa034401.62571735
27Regulation of autophagy_Homo sapiens_hsa041401.62001274
28Tryptophan metabolism_Homo sapiens_hsa003801.59709485
29Taste transduction_Homo sapiens_hsa047421.56736097
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56561743
31Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.55134152
32Oocyte meiosis_Homo sapiens_hsa041141.50995073
33Oxidative phosphorylation_Homo sapiens_hsa001901.49797643
34Renin secretion_Homo sapiens_hsa049241.42929984
35Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.35171888
36Purine metabolism_Homo sapiens_hsa002301.34787011
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.34138635
38Calcium signaling pathway_Homo sapiens_hsa040201.32711466
39beta-Alanine metabolism_Homo sapiens_hsa004101.31684064
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.30024793
41Phototransduction_Homo sapiens_hsa047441.29804246
42Retinol metabolism_Homo sapiens_hsa008301.29621442
43Histidine metabolism_Homo sapiens_hsa003401.28917939
44Propanoate metabolism_Homo sapiens_hsa006401.22897421
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.21544238
46Glycosaminoglycan degradation_Homo sapiens_hsa005311.17796035
47Sulfur metabolism_Homo sapiens_hsa009201.16107893
48Carbohydrate digestion and absorption_Homo sapiens_hsa049731.15889880
49Sphingolipid metabolism_Homo sapiens_hsa006001.15342097
50Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.13389015
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.11309990
52Parkinsons disease_Homo sapiens_hsa050121.09177512
53Ether lipid metabolism_Homo sapiens_hsa005651.07887535
54Morphine addiction_Homo sapiens_hsa050321.07749028
55Peroxisome_Homo sapiens_hsa041461.06290564
56RNA polymerase_Homo sapiens_hsa030201.05165568
57Glutamatergic synapse_Homo sapiens_hsa047241.05146634
58Circadian entrainment_Homo sapiens_hsa047131.04962469
59N-Glycan biosynthesis_Homo sapiens_hsa005101.04878793
60Mineral absorption_Homo sapiens_hsa049781.03963314
61RNA degradation_Homo sapiens_hsa030181.01916604
62Long-term potentiation_Homo sapiens_hsa047200.99495906
63Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95579327
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.95217975
65One carbon pool by folate_Homo sapiens_hsa006700.94232182
66Cardiac muscle contraction_Homo sapiens_hsa042600.93910839
67Arachidonic acid metabolism_Homo sapiens_hsa005900.93787159
68Selenocompound metabolism_Homo sapiens_hsa004500.92262518
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.90458573
70RNA transport_Homo sapiens_hsa030130.89892822
71Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89285819
72Glycerophospholipid metabolism_Homo sapiens_hsa005640.87111676
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.86701902
74Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.85117724
75Collecting duct acid secretion_Homo sapiens_hsa049660.82791449
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.82628198
77Insulin secretion_Homo sapiens_hsa049110.82562985
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82153251
79Wnt signaling pathway_Homo sapiens_hsa043100.82144688
80Glycerolipid metabolism_Homo sapiens_hsa005610.81335624
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80881739
82Pentose phosphate pathway_Homo sapiens_hsa000300.80223203
83Tyrosine metabolism_Homo sapiens_hsa003500.79969636
84Steroid biosynthesis_Homo sapiens_hsa001000.78717012
85Cell cycle_Homo sapiens_hsa041100.77821996
86Non-homologous end-joining_Homo sapiens_hsa034500.77650595
87Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.75703550
88cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73348432
89Autoimmune thyroid disease_Homo sapiens_hsa053200.72920706
90Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.72765857
91Fatty acid degradation_Homo sapiens_hsa000710.72710947
92Synaptic vesicle cycle_Homo sapiens_hsa047210.71053140
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.70726178
94ABC transporters_Homo sapiens_hsa020100.70440144
95Metabolic pathways_Homo sapiens_hsa011000.69343335
96Measles_Homo sapiens_hsa051620.68090388
97cAMP signaling pathway_Homo sapiens_hsa040240.66793454
98GABAergic synapse_Homo sapiens_hsa047270.63037721
99Phenylalanine metabolism_Homo sapiens_hsa003600.62575995
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.62529625
101Alzheimers disease_Homo sapiens_hsa050100.61767983
102Hedgehog signaling pathway_Homo sapiens_hsa043400.60516200
103Glutathione metabolism_Homo sapiens_hsa004800.59488513
104Inositol phosphate metabolism_Homo sapiens_hsa005620.59362278
105Rheumatoid arthritis_Homo sapiens_hsa053230.59110371
106SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58283257
107Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56725544
108Mismatch repair_Homo sapiens_hsa034300.55942621
109Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55317554
110Antigen processing and presentation_Homo sapiens_hsa046120.54410487
111Asthma_Homo sapiens_hsa053100.53319102
112Serotonergic synapse_Homo sapiens_hsa047260.53193619
113Salivary secretion_Homo sapiens_hsa049700.53149720
114Influenza A_Homo sapiens_hsa051640.52858145
115Systemic lupus erythematosus_Homo sapiens_hsa053220.52578747
116Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52279250
117Proteasome_Homo sapiens_hsa030500.51561757
118Pyrimidine metabolism_Homo sapiens_hsa002400.50789289
119Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50596743
120Herpes simplex infection_Homo sapiens_hsa051680.50500607
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50219407
122Base excision repair_Homo sapiens_hsa034100.49933959
123Alcoholism_Homo sapiens_hsa050340.47975867
124Fructose and mannose metabolism_Homo sapiens_hsa000510.46927496
125Fat digestion and absorption_Homo sapiens_hsa049750.46515227
126Cysteine and methionine metabolism_Homo sapiens_hsa002700.46219809
127Ovarian steroidogenesis_Homo sapiens_hsa049130.44773644
128Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.44329432
129Graft-versus-host disease_Homo sapiens_hsa053320.43460769
130Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43188196
131Legionellosis_Homo sapiens_hsa051340.43037588
132Cocaine addiction_Homo sapiens_hsa050300.42615282
133Fatty acid metabolism_Homo sapiens_hsa012120.41710224
134Axon guidance_Homo sapiens_hsa043600.41703085
135Vascular smooth muscle contraction_Homo sapiens_hsa042700.41612758
136Nucleotide excision repair_Homo sapiens_hsa034200.40427474
137Basal cell carcinoma_Homo sapiens_hsa052170.40291901
138Oxytocin signaling pathway_Homo sapiens_hsa049210.39674392
139Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39311719
140Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.37963508
141Circadian rhythm_Homo sapiens_hsa047100.37464668
142Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37395255
143Spliceosome_Homo sapiens_hsa030400.36873686
144MAPK signaling pathway_Homo sapiens_hsa040100.35491818
145Dopaminergic synapse_Homo sapiens_hsa047280.34813632
146Other glycan degradation_Homo sapiens_hsa005110.34183054
147Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33916247
148Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.33754142
149Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.33223175
150Phagosome_Homo sapiens_hsa041450.32696304

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