KLHDC9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane organization (GO:0097090)5.87366129
2presynaptic membrane assembly (GO:0097105)5.80853780
3axonemal dynein complex assembly (GO:0070286)5.77894045
4regulation of synapse structural plasticity (GO:0051823)5.63907884
5neuron cell-cell adhesion (GO:0007158)5.21719967
6cilium movement (GO:0003341)5.02492273
7cilium or flagellum-dependent cell motility (GO:0001539)4.75536113
8regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.59622928
9behavioral response to ethanol (GO:0048149)4.53047416
10intraciliary transport (GO:0042073)4.51795237
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.50602167
12epithelial cilium movement (GO:0003351)4.26844284
13regulation of cilium movement (GO:0003352)4.23392999
14synaptic vesicle maturation (GO:0016188)4.23026991
15central nervous system myelination (GO:0022010)4.19965472
16axon ensheathment in central nervous system (GO:0032291)4.19965472
17motile cilium assembly (GO:0044458)4.19549562
18axoneme assembly (GO:0035082)4.19032712
19left/right pattern formation (GO:0060972)4.05594981
20synaptic vesicle exocytosis (GO:0016079)4.02664876
21negative regulation of neurotransmitter secretion (GO:0046929)4.00290236
22epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.98584943
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.93039794
24vocalization behavior (GO:0071625)3.89134448
25synaptic transmission, dopaminergic (GO:0001963)3.88942353
26GTP biosynthetic process (GO:0006183)3.88589215
27postsynaptic membrane organization (GO:0001941)3.87820099
28mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.77964784
29ATP synthesis coupled proton transport (GO:0015986)3.71622240
30energy coupled proton transport, down electrochemical gradient (GO:0015985)3.71622240
31ventricular system development (GO:0021591)3.70987537
32ionotropic glutamate receptor signaling pathway (GO:0035235)3.68966114
33negative regulation of neurotransmitter transport (GO:0051589)3.68790088
34response to histamine (GO:0034776)3.66198714
35pyrimidine nucleobase catabolic process (GO:0006208)3.63808929
36short-term memory (GO:0007614)3.60825339
37regulation of short-term neuronal synaptic plasticity (GO:0048172)3.60254173
38neuronal action potential propagation (GO:0019227)3.57529236
39regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.56448888
40positive regulation of dendritic spine development (GO:0060999)3.55414197
41nucleoside diphosphate phosphorylation (GO:0006165)3.52783284
42positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.52720114
43glutamate secretion (GO:0014047)3.48492403
44positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.45692912
45membrane hyperpolarization (GO:0060081)3.45520423
46positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.43369328
47neuron-neuron synaptic transmission (GO:0007270)3.41486217
48cilium organization (GO:0044782)3.39899649
49synaptic transmission, glutamatergic (GO:0035249)3.36335933
50behavioral response to cocaine (GO:0048148)3.36111299
51behavioral fear response (GO:0001662)3.34925544
52behavioral defense response (GO:0002209)3.34925544
53negative regulation of execution phase of apoptosis (GO:1900118)3.33265262
54cilium assembly (GO:0042384)3.32785495
55UTP biosynthetic process (GO:0006228)3.27552246
56glutamate receptor signaling pathway (GO:0007215)3.27288903
57positive regulation of membrane potential (GO:0045838)3.22539710
58cilium morphogenesis (GO:0060271)3.21999707
59regulation of dopamine metabolic process (GO:0042053)3.20513300
60regulation of catecholamine metabolic process (GO:0042069)3.20513300
61regulation of glutamate receptor signaling pathway (GO:1900449)3.19778196
62regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.17483099
63purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.15500388
64protein localization to synapse (GO:0035418)3.11907837
65response to amphetamine (GO:0001975)3.10847211
66fear response (GO:0042596)3.10831976
67regulation of microtubule-based movement (GO:0060632)3.10306324
68transmission of nerve impulse (GO:0019226)3.09976169
69regulation of voltage-gated calcium channel activity (GO:1901385)3.09356091
70positive regulation of mitochondrial fission (GO:0090141)3.08839752
71regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.08781809
72regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.08781809
73positive regulation of synapse assembly (GO:0051965)3.05450246
74nucleobase catabolic process (GO:0046113)3.05064595
75purine nucleoside triphosphate biosynthetic process (GO:0009145)3.04943901
76neuron recognition (GO:0008038)3.03518267
77respiratory electron transport chain (GO:0022904)3.02187187
78dopamine biosynthetic process (GO:0042416)3.00656908
79negative regulation of inclusion body assembly (GO:0090084)3.00175113
80chemosensory behavior (GO:0007635)2.97217056
81electron transport chain (GO:0022900)2.95921502
82protein complex biogenesis (GO:0070271)2.95185189
83long-chain fatty acid biosynthetic process (GO:0042759)2.94875850
84ATP biosynthetic process (GO:0006754)2.94617866
85microtubule bundle formation (GO:0001578)2.93962100
86detection of calcium ion (GO:0005513)2.93894735
87protein localization to cilium (GO:0061512)2.93448164
88negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.92883240
89UTP metabolic process (GO:0046051)2.92769355
90regulation of dendritic spine development (GO:0060998)2.92393189
91positive regulation of neurotransmitter transport (GO:0051590)2.92271040
92regulation of excitatory postsynaptic membrane potential (GO:0060079)2.91603304
93membrane assembly (GO:0071709)2.90725425
94dendritic spine morphogenesis (GO:0060997)2.88157422
95female mating behavior (GO:0060180)2.87896877
96left/right axis specification (GO:0070986)2.86231192
97regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.85411673
98CTP metabolic process (GO:0046036)2.83553643
99CTP biosynthetic process (GO:0006241)2.83553643
100positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.83508948
101ribonucleoside triphosphate biosynthetic process (GO:0009201)2.79971177
102neurotransmitter secretion (GO:0007269)2.76425461
103microtubule-based movement (GO:0007018)2.75735653
104regulation of postsynaptic membrane potential (GO:0060078)2.74872455
105axonal fasciculation (GO:0007413)2.73206326
106regulation of inositol phosphate biosynthetic process (GO:0010919)2.73123157
107establishment of mitochondrion localization (GO:0051654)2.72202219
108regulation of synaptic vesicle exocytosis (GO:2000300)2.71736978
109mitochondrial respiratory chain complex assembly (GO:0033108)2.70981178
110regulation of long-term neuronal synaptic plasticity (GO:0048169)2.70980871
111retinal ganglion cell axon guidance (GO:0031290)2.70921261
112regulation of protein kinase A signaling (GO:0010738)2.70413030
113nonribosomal peptide biosynthetic process (GO:0019184)2.69565771
114nonmotile primary cilium assembly (GO:0035058)2.68285482
115adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.67204006
116regulation of neurotransmitter secretion (GO:0046928)2.66985315
117regulation of female receptivity (GO:0045924)2.66959947
118regulation of collateral sprouting (GO:0048670)2.66535407
119gamma-aminobutyric acid signaling pathway (GO:0007214)2.66384123
120auditory behavior (GO:0031223)2.65839266
121mannosylation (GO:0097502)2.65360360
122regulation of neurotransmitter uptake (GO:0051580)2.64371221
123mitochondrial respiratory chain complex I assembly (GO:0032981)2.63368166
124NADH dehydrogenase complex assembly (GO:0010257)2.63368166
125mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.63368166
126smoothened signaling pathway (GO:0007224)2.57146028
127neurofilament cytoskeleton organization (GO:0060052)2.57070394
128protein polyglutamylation (GO:0018095)2.56850736
129cellular component assembly involved in morphogenesis (GO:0010927)2.53946161
130neurotransmitter-gated ion channel clustering (GO:0072578)2.49562766
131pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.47004094
132negative regulation of synaptic transmission, GABAergic (GO:0032229)2.44349653
133membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.44075796
134determination of left/right symmetry (GO:0007368)2.41792379
135cytoskeleton-dependent intracellular transport (GO:0030705)2.41510781
136regulation of synaptic vesicle transport (GO:1902803)2.40520898
137dorsal/ventral neural tube patterning (GO:0021904)2.40304681
138response to auditory stimulus (GO:0010996)2.38386514
139behavioral response to nicotine (GO:0035095)2.37465655
140microtubule-based transport (GO:0010970)2.35388449
141synapse assembly (GO:0007416)2.31517126
142negative regulation of appetite (GO:0032099)2.31512736
143negative regulation of response to food (GO:0032096)2.31512736
144synaptic vesicle endocytosis (GO:0048488)2.31488927
145pyrimidine nucleotide catabolic process (GO:0006244)2.31118980
146retinal rod cell development (GO:0046548)2.30586217
147determination of bilateral symmetry (GO:0009855)2.30514130
148neuronal ion channel clustering (GO:0045161)2.30513746
149retinal cone cell development (GO:0046549)2.30285178
150glycosphingolipid biosynthetic process (GO:0006688)2.28784802
151ATP hydrolysis coupled proton transport (GO:0015991)2.28145135
152energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.28145135
153mechanosensory behavior (GO:0007638)2.26861028
154sperm capacitation (GO:0048240)2.25705743
155specification of symmetry (GO:0009799)2.25687724
156positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.25524373

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.66403228
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.27832692
3GBX2_23144817_ChIP-Seq_PC3_Human3.14482200
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00347815
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.91042766
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.87995154
7JARID2_20075857_ChIP-Seq_MESCs_Mouse2.63219589
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.59369910
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.57231119
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.54470141
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45876013
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.44228254
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.35250850
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.34672362
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.34672362
16BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.33420397
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.31486652
18TAF15_26573619_Chip-Seq_HEK293_Human2.24384769
19CTBP2_25329375_ChIP-Seq_LNCAP_Human2.23669405
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.19508826
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.15270816
22REST_21632747_ChIP-Seq_MESCs_Mouse2.15099574
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.14352371
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.03970686
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.99211430
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.98204152
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.97552529
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.96203472
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.95707408
30AR_21572438_ChIP-Seq_LNCaP_Human1.94686155
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.90004265
32FUS_26573619_Chip-Seq_HEK293_Human1.85894978
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.83287550
34P300_19829295_ChIP-Seq_ESCs_Human1.76811481
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76357499
36IGF1R_20145208_ChIP-Seq_DFB_Human1.74658535
37HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.74221946
38SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.69470714
39IKZF1_21737484_ChIP-ChIP_HCT116_Human1.66553721
40RNF2_27304074_Chip-Seq_NSC_Mouse1.65398893
41CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.63830713
42DROSHA_22980978_ChIP-Seq_HELA_Human1.61831720
43NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.60870029
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.58905256
45REST_18959480_ChIP-ChIP_MESCs_Mouse1.58806783
46ZNF274_21170338_ChIP-Seq_K562_Hela1.58568576
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57461364
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.57278962
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57264407
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54384884
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53126373
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.51780432
53SMAD4_21799915_ChIP-Seq_A2780_Human1.49700265
54SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.48620929
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.48065430
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47721736
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46238700
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.37873251
59ERG_21242973_ChIP-ChIP_JURKAT_Human1.34742128
60ER_23166858_ChIP-Seq_MCF-7_Human1.33241301
61ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.31925391
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.27487202
63TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27469210
64SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27398863
65SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.24906564
66RARB_27405468_Chip-Seq_BRAIN_Mouse1.24117427
67* NANOG_18555785_Chip-Seq_ESCs_Mouse1.23113422
68VDR_22108803_ChIP-Seq_LS180_Human1.21967947
69RING1B_27294783_Chip-Seq_ESCs_Mouse1.21256798
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18631091
71TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18386014
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.17950234
73MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.16176786
74GATA1_26923725_Chip-Seq_HPCs_Mouse1.15851068
75FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.15786963
76MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15700717
77CTCF_27219007_Chip-Seq_Bcells_Human1.15269386
78GABP_17652178_ChIP-ChIP_JURKAT_Human1.13824729
79AR_25329375_ChIP-Seq_VCAP_Human1.12943686
80TP53_18474530_ChIP-ChIP_U2OS_Human1.11950298
81KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.10945136
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.08671388
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07913291
84TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05479874
85IRF1_19129219_ChIP-ChIP_H3396_Human1.04885826
86MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04779410
87RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.04522021
88SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.04360523
89* E2F1_18555785_Chip-Seq_ESCs_Mouse1.02785887
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00937427
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00937427
92* CMYC_18555785_Chip-Seq_ESCs_Mouse1.00857343
93* P53_22387025_ChIP-Seq_ESCs_Mouse1.00643735
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00461658
95RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.00428047
96* STAT3_18555785_Chip-Seq_ESCs_Mouse0.98012681
97ARNT_22903824_ChIP-Seq_MCF-7_Human0.98007570
98BCAT_22108803_ChIP-Seq_LS180_Human0.97771667
99* SOX2_18555785_Chip-Seq_ESCs_Mouse0.97650079
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97648604
101CBP_20019798_ChIP-Seq_JUKART_Human0.97648604
102* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.97477704
103TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97336616
104SMAD4_21741376_ChIP-Seq_EPCs_Human0.97193413
105* P300_18555785_Chip-Seq_ESCs_Mouse0.96123101
106MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.95757971
107TAL1_26923725_Chip-Seq_HPCs_Mouse0.95731979
108NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95572990
109RUNX2_22187159_ChIP-Seq_PCA_Human0.94795651
110AHR_22903824_ChIP-Seq_MCF-7_Human0.94518882
111TCF4_23295773_ChIP-Seq_U87_Human0.93734592
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91902523
113KDM2B_26808549_Chip-Seq_REH_Human0.91353932
114AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91164630
115ERA_21632823_ChIP-Seq_H3396_Human0.90888420
116TRIM28_21343339_ChIP-Seq_HEK293_Human0.90833926
117MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90572019
118EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.90073531
119ETV2_25802403_ChIP-Seq_MESCs_Mouse0.90060010
120JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.89623963
121LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89372194
122THAP11_20581084_ChIP-Seq_MESCs_Mouse0.88426141
123STAT3_23295773_ChIP-Seq_U87_Human0.88334931
124YY1_21170310_ChIP-Seq_MESCs_Mouse0.87635319
125* NMYC_18555785_Chip-Seq_ESCs_Mouse0.87029774
126RING1B_27294783_Chip-Seq_NPCs_Mouse0.86938383
127ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.86406821
128NCOR_22424771_ChIP-Seq_293T_Human0.85643111
129EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.84681085
130* SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.84363260
131P53_22127205_ChIP-Seq_FIBROBLAST_Human0.83592062
132EWS_26573619_Chip-Seq_HEK293_Human0.83455636
133WDR5_24793694_ChIP-Seq_LNCAP_Human0.81705517
134TP53_22573176_ChIP-Seq_HFKS_Human0.80516183
135KLF5_20875108_ChIP-Seq_MESCs_Mouse0.80427818
136PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.79857060
137OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.78898389
138MYC_18940864_ChIP-ChIP_HL60_Human0.78070574
139* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.78021357
140AR_19668381_ChIP-Seq_PC3_Human0.77636650
141POU5F1_16153702_ChIP-ChIP_HESCs_Human0.77599972

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.54845386
2MP0004859_abnormal_synaptic_plasticity3.83220380
3MP0003635_abnormal_synaptic_transmissio3.10508468
4MP0003136_yellow_coat_color3.10367713
5MP0009745_abnormal_behavioral_response2.96766464
6MP0002064_seizures2.70151689
7MP0006276_abnormal_autonomic_nervous2.69912340
8MP0003879_abnormal_hair_cell2.67337141
9MP0001984_abnormal_olfaction2.67190157
10MP0009046_muscle_twitch2.67002209
11MP0001968_abnormal_touch/_nociception2.59285566
12MP0009379_abnormal_foot_pigmentation2.50226486
13MP0001905_abnormal_dopamine_level2.45059003
14MP0002572_abnormal_emotion/affect_behav2.44623967
15MP0002272_abnormal_nervous_system2.44532476
16MP0002063_abnormal_learning/memory/cond2.44083966
17MP0005646_abnormal_pituitary_gland2.31426663
18MP0004270_analgesia2.24358686
19MP0003787_abnormal_imprinting2.24355628
20MP0001486_abnormal_startle_reflex2.23133785
21MP0005409_darkened_coat_color2.22469569
22MP0002734_abnormal_mechanical_nocicepti2.11338009
23MP0001440_abnormal_grooming_behavior2.09109615
24MP0001529_abnormal_vocalization2.05310146
25MP0001501_abnormal_sleep_pattern2.05201717
26MP0002736_abnormal_nociception_after2.03241331
27MP0006292_abnormal_olfactory_placode2.02115902
28MP0002909_abnormal_adrenal_gland1.97405853
29MP0005394_taste/olfaction_phenotype1.95440479
30MP0005499_abnormal_olfactory_system1.95440479
31MP0005410_abnormal_fertilization1.94710240
32MP0003283_abnormal_digestive_organ1.91691285
33MP0003690_abnormal_glial_cell1.90844790
34MP0003195_calcinosis1.87050637
35MP0005645_abnormal_hypothalamus_physiol1.85338032
36MP0003121_genomic_imprinting1.82466575
37MP0005423_abnormal_somatic_nervous1.77894772
38MP0008789_abnormal_olfactory_epithelium1.77526831
39MP0004742_abnormal_vestibular_system1.77288313
40MP0000778_abnormal_nervous_system1.71692802
41MP0002557_abnormal_social/conspecific_i1.70803483
42MP0001188_hyperpigmentation1.62815004
43MP0002067_abnormal_sensory_capabilities1.59279039
44MP0002184_abnormal_innervation1.58418879
45MP0002733_abnormal_thermal_nociception1.56923313
46MP0001970_abnormal_pain_threshold1.51213831
47MP0002735_abnormal_chemical_nociception1.46043261
48MP0000631_abnormal_neuroendocrine_gland1.42513395
49MP0003123_paternal_imprinting1.37169907
50MP0010386_abnormal_urinary_bladder1.37094993
51MP0003122_maternal_imprinting1.32515288
52MP0000013_abnormal_adipose_tissue1.31110264
53MP0005248_abnormal_Harderian_gland1.29676668
54MP0004145_abnormal_muscle_electrophysio1.28780463
55MP0005379_endocrine/exocrine_gland_phen1.28014793
56MP0000920_abnormal_myelination1.27937314
57MP0002822_catalepsy1.27666532
58MP0002882_abnormal_neuron_morphology1.27524541
59MP0004043_abnormal_pH_regulation1.26713692
60MP0005595_abnormal_vascular_smooth1.26184399
61MP0001963_abnormal_hearing_physiology1.25372090
62MP0003890_abnormal_embryonic-extraembry1.25267077
63MP0001485_abnormal_pinna_reflex1.25093112
64MP0004142_abnormal_muscle_tone1.23564937
65MP0002163_abnormal_gland_morphology1.23056582
66MP0002928_abnormal_bile_duct1.21694947
67MP0003329_amyloid_beta_deposits1.19826804
68MP0004924_abnormal_behavior1.19469882
69MP0005386_behavior/neurological_phenoty1.19469882
70MP0000026_abnormal_inner_ear1.17765979
71MP0002234_abnormal_pharynx_morphology1.17333089
72MP0005551_abnormal_eye_electrophysiolog1.13343075
73MP0008875_abnormal_xenobiotic_pharmacok1.13026772
74MP0003633_abnormal_nervous_system1.12897102
75MP0002066_abnormal_motor_capabilities/c1.12513781
76MP0002638_abnormal_pupillary_reflex1.10080873
77MP0003634_abnormal_glial_cell1.08693236
78MP0002132_abnormal_respiratory_system1.08673125
79MP0002233_abnormal_nose_morphology1.07446681
80MP0001502_abnormal_circadian_rhythm1.05933614
81MP0005623_abnormal_meninges_morphology1.01700156
82MP0006072_abnormal_retinal_apoptosis1.00834326
83MP0002938_white_spotting1.00145704
84MP0000955_abnormal_spinal_cord0.99408043
85MP0002752_abnormal_somatic_nervous0.98122132
86MP0004858_abnormal_nervous_system0.98009252
87MP0008874_decreased_physiological_sensi0.94543304
88MP0004885_abnormal_endolymph0.93901527
89MP0003938_abnormal_ear_development0.91339480
90MP0002152_abnormal_brain_morphology0.90818118
91MP0003698_abnormal_male_reproductive0.90417281
92MP0008569_lethality_at_weaning0.88739426
93MP0002876_abnormal_thyroid_physiology0.88541895
94MP0005195_abnormal_posterior_eye0.86239034
95MP0005171_absent_coat_pigmentation0.85172721
96MP0003861_abnormal_nervous_system0.84842469
97MP0002229_neurodegeneration0.84687818
98MP0005451_abnormal_body_composition0.82833321
99MP0003631_nervous_system_phenotype0.82741728
100MP0001986_abnormal_taste_sensitivity0.82605470
101MP0002277_abnormal_respiratory_mucosa0.80228093
102MP0004811_abnormal_neuron_physiology0.80197519
103MP0000462_abnormal_digestive_system0.79402653
104MP0002160_abnormal_reproductive_system0.79019282
105MP0009250_abnormal_appendicular_skeleto0.77602554
106MP0006035_abnormal_mitochondrial_morpho0.77433200
107MP0001346_abnormal_lacrimal_gland0.76415759
108MP0003119_abnormal_digestive_system0.76348046
109MP0002069_abnormal_eating/drinking_beha0.75614169
110MP0000566_synostosis0.75371499
111MP0010030_abnormal_orbit_morphology0.74557836
112MP0000751_myopathy0.72826200
113MP0001727_abnormal_embryo_implantation0.71734142
114MP0001177_atelectasis0.71688203
115MP0005253_abnormal_eye_physiology0.69009766
116MP0001664_abnormal_digestion0.68186697
117MP0008872_abnormal_physiological_respon0.67905778
118MP0004133_heterotaxia0.67855279
119MP0000049_abnormal_middle_ear0.67424016
120MP0002653_abnormal_ependyma_morphology0.67360794
121MP0003137_abnormal_impulse_conducting0.67082583
122MP0008877_abnormal_DNA_methylation0.67062188
123MP0005084_abnormal_gallbladder_morpholo0.62989291
124MP0002837_dystrophic_cardiac_calcinosis0.62787342
125MP0002102_abnormal_ear_morphology0.62182778
126MP0000604_amyloidosis0.60191027

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)6.68072541
2Abnormal respiratory motile cilium physiology (HP:0012261)6.34768783
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.91812944
4Rhinitis (HP:0012384)5.66227008
5Abnormal respiratory motile cilium morphology (HP:0005938)5.62005009
6Abnormal respiratory epithelium morphology (HP:0012253)5.62005009
7Absent/shortened dynein arms (HP:0200106)4.74813620
8Dynein arm defect of respiratory motile cilia (HP:0012255)4.74813620
9Focal motor seizures (HP:0011153)4.63912305
10Degeneration of the lateral corticospinal tracts (HP:0002314)4.16471039
11Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.16471039
12Retinal dysplasia (HP:0007973)3.66290266
13Myokymia (HP:0002411)3.44557364
14Abnormality of the corticospinal tract (HP:0002492)3.35684008
15Molar tooth sign on MRI (HP:0002419)3.23850010
16Abnormality of midbrain morphology (HP:0002418)3.23850010
17Bronchiectasis (HP:0002110)3.06707899
18Median cleft lip (HP:0000161)2.98637467
19Impaired vibration sensation in the lower limbs (HP:0002166)2.97451312
20Nephronophthisis (HP:0000090)2.90886744
21Neurofibrillary tangles (HP:0002185)2.87824694
22Sensory axonal neuropathy (HP:0003390)2.84338766
23Polyphagia (HP:0002591)2.79299010
24Cystic liver disease (HP:0006706)2.67458770
25Acute necrotizing encephalopathy (HP:0006965)2.63602737
26Chronic bronchitis (HP:0004469)2.63599866
27Focal seizures (HP:0007359)2.63338376
28Absent speech (HP:0001344)2.59630490
29Epileptic encephalopathy (HP:0200134)2.57180862
30Visual hallucinations (HP:0002367)2.53570763
31Pancreatic fibrosis (HP:0100732)2.51502422
323-Methylglutaconic aciduria (HP:0003535)2.48275920
33Insidious onset (HP:0003587)2.43377335
34Termporal pattern (HP:0011008)2.43377335
35Medial flaring of the eyebrow (HP:0010747)2.43092739
36Atonic seizures (HP:0010819)2.41942149
37Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.40711719
38Mitochondrial inheritance (HP:0001427)2.39134645
39Gait imbalance (HP:0002141)2.38296485
40Type II lissencephaly (HP:0007260)2.37353767
41Sclerocornea (HP:0000647)2.35791764
42True hermaphroditism (HP:0010459)2.33754770
43Stomach cancer (HP:0012126)2.33611967
44Progressive cerebellar ataxia (HP:0002073)2.31878703
45Abnormal eating behavior (HP:0100738)2.30852921
46Aplasia involving bones of the upper limbs (HP:0009823)2.30622763
47Aplasia of the phalanges of the hand (HP:0009802)2.30622763
48Aplasia involving bones of the extremities (HP:0009825)2.30622763
49Hyperglycinemia (HP:0002154)2.29561071
50Febrile seizures (HP:0002373)2.27432022
51Abnormality of the renal medulla (HP:0100957)2.26672240
52Occipital encephalocele (HP:0002085)2.24438946
53Male infertility (HP:0003251)2.22150593
54Anencephaly (HP:0002323)2.21146694
55Congenital primary aphakia (HP:0007707)2.17942763
56Chronic hepatic failure (HP:0100626)2.16686330
57Generalized tonic-clonic seizures (HP:0002069)2.14161210
58Failure to thrive in infancy (HP:0001531)2.14056129
59Cerebral inclusion bodies (HP:0100314)2.12216894
60Increased intramyocellular lipid droplets (HP:0012240)2.11693918
61Absent septum pellucidum (HP:0001331)2.11437210
62Optic nerve hypoplasia (HP:0000609)2.11282676
63Renal Fanconi syndrome (HP:0001994)2.09833445
64Hemiparesis (HP:0001269)2.08508365
65Chronic sinusitis (HP:0011109)2.07262790
66Abnormal mitochondria in muscle tissue (HP:0008316)2.06706635
67Increased hepatocellular lipid droplets (HP:0006565)2.04831929
68Progressive macrocephaly (HP:0004481)2.04263799
69Congenital hepatic fibrosis (HP:0002612)2.02150406
70Acute encephalopathy (HP:0006846)2.01795788
71Nephrogenic diabetes insipidus (HP:0009806)1.99583926
72Vaginal atresia (HP:0000148)1.99519099
73Taurodontia (HP:0000679)1.99294258
74Abnormality of permanent molar morphology (HP:0011071)1.99294258
75Abnormality of the dental root (HP:0006486)1.99294258
76Abnormality of renal resorption (HP:0011038)1.98760557
77Spastic gait (HP:0002064)1.97866042
78Postaxial hand polydactyly (HP:0001162)1.97382392
79Genital tract atresia (HP:0001827)1.97174874
80Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.95914932
81Increased CSF lactate (HP:0002490)1.95824327
82Short tibia (HP:0005736)1.93903655
83Aplasia/Hypoplasia of the tongue (HP:0010295)1.93401735
84Abnormality of the dental pulp (HP:0006479)1.92892241
85Septo-optic dysplasia (HP:0100842)1.92392865
86Stage 5 chronic kidney disease (HP:0003774)1.91559882
87Neuroendocrine neoplasm (HP:0100634)1.91506746
88Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.91210234
89Decreased activity of mitochondrial respiratory chain (HP:0008972)1.91210234
90Absence seizures (HP:0002121)1.90993063
91Nasal polyposis (HP:0100582)1.89938202
92Polydipsia (HP:0001959)1.88877347
93Abnormal drinking behavior (HP:0030082)1.88877347
94Broad foot (HP:0001769)1.88025432
95Aplasia/Hypoplasia of the tibia (HP:0005772)1.87694228
96Infertility (HP:0000789)1.86588093
97Bifid tongue (HP:0010297)1.85543371
98Hepatocellular necrosis (HP:0001404)1.85468896
99Dialeptic seizures (HP:0011146)1.85337807
100Preaxial hand polydactyly (HP:0001177)1.85250286
101Specific learning disability (HP:0001328)1.85037799
102Urinary bladder sphincter dysfunction (HP:0002839)1.84486489
103Poor coordination (HP:0002370)1.83456493
104Pancreatic cysts (HP:0001737)1.83298525
105Tubulointerstitial nephritis (HP:0001970)1.82911636
106Hepatic necrosis (HP:0002605)1.82834538
107Optic disc pallor (HP:0000543)1.82703522
108Inability to walk (HP:0002540)1.82086064
109Male pseudohermaphroditism (HP:0000037)1.81941486
110Abnormality of the labia minora (HP:0012880)1.81416696
111Hyperglycinuria (HP:0003108)1.80960990
112Supernumerary spleens (HP:0009799)1.80861422
113Lipid accumulation in hepatocytes (HP:0006561)1.80188492
114Sleep apnea (HP:0010535)1.79355780
115Abnormality of molar morphology (HP:0011070)1.79211955
116Abnormality of molar (HP:0011077)1.79211955
117Abnormality of the septum pellucidum (HP:0007375)1.78869315
118Limb dystonia (HP:0002451)1.78073201
119Increased circulating renin level (HP:0000848)1.78073150
120Narrow forehead (HP:0000341)1.76203410
121Polyuria (HP:0000103)1.75190295
122Epileptiform EEG discharges (HP:0011182)1.74751029
123Atelectasis (HP:0100750)1.74433210
124Amblyopia (HP:0000646)1.74117029
125Postaxial foot polydactyly (HP:0001830)1.73966618
126Cerebral edema (HP:0002181)1.73780864
127Hypsarrhythmia (HP:0002521)1.73532233
128Anxiety (HP:0000739)1.73107042
129Abnormality of glycine metabolism (HP:0010895)1.70999420
130Abnormality of serine family amino acid metabolism (HP:0010894)1.70999420
131Confusion (HP:0001289)1.70470893
132Abnormality of the anterior horn cell (HP:0006802)1.69863316
133Degeneration of anterior horn cells (HP:0002398)1.69863316
134Lissencephaly (HP:0001339)1.69716532
135EEG with generalized epileptiform discharges (HP:0011198)1.69339937
136Oculomotor apraxia (HP:0000657)1.63983023
137Poor suck (HP:0002033)1.63508098
138Abnormality of the lower motor neuron (HP:0002366)1.62135643
139Renal salt wasting (HP:0000127)1.60633625
140Tubular atrophy (HP:0000092)1.58238274
141Exercise intolerance (HP:0003546)1.56259014
142Hypomagnesemia (HP:0002917)1.53790500
143Hyperphosphaturia (HP:0003109)1.52914726
144Glycosuria (HP:0003076)1.51288709
145Abnormality of urine glucose concentration (HP:0011016)1.51288709
146Abnormality of the renal cortex (HP:0011035)1.50762183
147Colon cancer (HP:0003003)1.50510916
148Prominent nasal bridge (HP:0000426)1.49652192

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CAMKK25.78510079
2CAMK1D4.78993969
3CAMK1G4.18955984
4MAPK153.21836810
5CASK3.19604790
6EPHA42.70789149
7CAMKK12.58505320
8PNCK2.55878988
9MAP4K22.43805158
10NTRK32.35221705
11MAP3K92.18543441
12NTRK22.03611438
13DYRK21.91422340
14TNIK1.85474424
15BCKDK1.80807352
16ARAF1.74027762
17WNK41.71986153
18DYRK1B1.66819500
19MAP2K71.54739130
20NME11.54447571
21TRIM281.54175217
22STK391.50181515
23STK161.49268452
24DYRK31.48560691
25CAMK11.47650193
26FES1.44646899
27MAPKAPK51.40836136
28LIMK11.39533779
29NTRK11.37956794
30OXSR11.36172918
31RIPK41.29201051
32ADRBK21.27827599
33WNK31.25179730
34MARK11.23472331
35MAPK131.23220029
36MAP3K131.22621999
37MINK11.18283877
38FGR1.11595652
39PRKCG1.11424632
40BMPR1B1.09664273
41PRKD31.07821220
42MST41.06012966
43MUSK1.05971759
44SGK4941.05591559
45SGK2231.05591559
46MAP2K41.05111842
47CAMK2B1.04454310
48UHMK11.03827030
49PAK60.94562483
50WNK10.92482594
51CDK50.90364725
52MAP3K120.87592265
53CAMK2A0.86506529
54CDK30.84049894
55TNK20.83000466
56KSR20.82949558
57TIE10.82167711
58PKN10.81753382
59TESK10.81360651
60GRK50.81030279
61VRK20.78319731
62ADRBK10.76992980
63CAMK2G0.76645576
64MAP3K40.76326047
65PRKCI0.76057685
66TYRO30.74853142
67ERBB30.74414864
68LRRK20.73566150
69ROCK20.72954874
70PHKG10.72510415
71PHKG20.72510415
72CDK190.69553431
73PRKCE0.69147688
74CSNK1G30.69100628
75FRK0.68736000
76CAMK2D0.66985341
77PAK30.65780149
78VRK10.65645783
79CAMK40.65187548
80GRK10.63687234
81FGFR20.63027576
82RAF10.62845636
83BMPR20.62511788
84PLK10.58972302
85NEK10.58779735
86CSNK1A1L0.58681475
87CSNK1G20.57892267
88PRKCZ0.57403428
89PRPF4B0.56935402
90KSR10.55914981
91MARK20.53786826
92SGK20.53566812
93PINK10.53556027
94CDK80.53210620
95CDK150.51726033
96SIK20.51604436
97CDK180.50477677
98LMTK20.50304205
99CSNK1E0.50246804
100PRKG20.50132207
101DDR20.49122547
102CDK140.48385780
103PRKG10.46903155
104ZAK0.46527942
105PLK20.45879243
106MAP3K70.44656353
107IRAK20.44639498
108PRKACA0.44049472
109CDC42BPA0.43980489
110RPS6KA50.43703008
111BRSK10.43668742
112CDK11A0.43598160
113EPHA20.43339000
114EPHB20.43314802
115IRAK10.43280134
116PRKACB0.42713108
117PTK2B0.42223794
118CSNK1G10.40942273
119PRKAA10.39956448
120PIM20.39954564
121DAPK20.39736816
122SGK10.38143762
123INSRR0.38047873
124PRKDC0.38036108
125CCNB10.37966394
126STK110.36223189
127NEK60.34826461
128BRAF0.33479628
129FYN0.33423108
130DYRK1A0.33200345
131BCR0.31520743
132PRKCH0.31432893
133AURKA0.27254433
134PRKCA0.27060862
135MYLK0.26394264
136MAP3K10.25007436
137CSNK1A10.24062864

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.74432472
2Nicotine addiction_Homo sapiens_hsa050333.70193982
3Parkinsons disease_Homo sapiens_hsa050122.81665174
4Olfactory transduction_Homo sapiens_hsa047402.68794577
5Alzheimers disease_Homo sapiens_hsa050102.53167370
6GABAergic synapse_Homo sapiens_hsa047272.38515564
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.34602472
8Glutamatergic synapse_Homo sapiens_hsa047242.28421376
9Huntingtons disease_Homo sapiens_hsa050162.26767968
10Circadian entrainment_Homo sapiens_hsa047132.17513161
11Synaptic vesicle cycle_Homo sapiens_hsa047212.12905268
12Collecting duct acid secretion_Homo sapiens_hsa049662.04508212
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.04037870
14Morphine addiction_Homo sapiens_hsa050322.03563133
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.96942265
16Cardiac muscle contraction_Homo sapiens_hsa042601.94161716
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.93938396
18Amphetamine addiction_Homo sapiens_hsa050311.92577123
19Phenylalanine metabolism_Homo sapiens_hsa003601.87166126
20Taste transduction_Homo sapiens_hsa047421.85981258
21Salivary secretion_Homo sapiens_hsa049701.84998667
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.83250804
23Insulin secretion_Homo sapiens_hsa049111.82992069
24Sulfur relay system_Homo sapiens_hsa041221.73657340
25Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.72156804
26Cocaine addiction_Homo sapiens_hsa050301.56957143
27Gastric acid secretion_Homo sapiens_hsa049711.56399381
28Dopaminergic synapse_Homo sapiens_hsa047281.54341308
29Protein export_Homo sapiens_hsa030601.52641906
30Propanoate metabolism_Homo sapiens_hsa006401.52320879
31Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.52065102
32Serotonergic synapse_Homo sapiens_hsa047261.51375263
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51351360
34Calcium signaling pathway_Homo sapiens_hsa040201.50078822
35Renin secretion_Homo sapiens_hsa049241.48620142
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46752482
37Cholinergic synapse_Homo sapiens_hsa047251.46015107
38beta-Alanine metabolism_Homo sapiens_hsa004101.45672451
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.45237198
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.42668960
41Long-term potentiation_Homo sapiens_hsa047201.36362775
42Peroxisome_Homo sapiens_hsa041461.36127881
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36064438
44Phototransduction_Homo sapiens_hsa047441.34638094
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.34513857
46Ether lipid metabolism_Homo sapiens_hsa005651.32155911
47Vibrio cholerae infection_Homo sapiens_hsa051101.31944455
48Sulfur metabolism_Homo sapiens_hsa009201.28718044
49Folate biosynthesis_Homo sapiens_hsa007901.26540876
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.24409706
51Oxytocin signaling pathway_Homo sapiens_hsa049211.24112160
52Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.19400495
53Long-term depression_Homo sapiens_hsa047301.16805545
54Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.16464384
55Tyrosine metabolism_Homo sapiens_hsa003501.15759976
56cAMP signaling pathway_Homo sapiens_hsa040241.14259499
57Histidine metabolism_Homo sapiens_hsa003401.11941384
58Ribosome_Homo sapiens_hsa030101.10711579
59Chemical carcinogenesis_Homo sapiens_hsa052041.07017604
60Primary bile acid biosynthesis_Homo sapiens_hsa001201.06847273
61Vascular smooth muscle contraction_Homo sapiens_hsa042701.06690353
62Axon guidance_Homo sapiens_hsa043601.02856804
63Regulation of autophagy_Homo sapiens_hsa041400.98147852
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.90874287
65Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89317176
66Vitamin B6 metabolism_Homo sapiens_hsa007500.88936235
67Prion diseases_Homo sapiens_hsa050200.88662369
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87177291
69Gap junction_Homo sapiens_hsa045400.86778072
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85520933
71Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.83735146
72Rheumatoid arthritis_Homo sapiens_hsa053230.83166184
73Melanogenesis_Homo sapiens_hsa049160.82022524
74Basal cell carcinoma_Homo sapiens_hsa052170.81534279
75Pancreatic secretion_Homo sapiens_hsa049720.81478619
76Estrogen signaling pathway_Homo sapiens_hsa049150.80767502
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.80507788
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80015254
79Fatty acid metabolism_Homo sapiens_hsa012120.79405815
80Biosynthesis of amino acids_Homo sapiens_hsa012300.76823216
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.76804110
82GnRH signaling pathway_Homo sapiens_hsa049120.76010806
83Fanconi anemia pathway_Homo sapiens_hsa034600.75572280
84Butanoate metabolism_Homo sapiens_hsa006500.75390065
85Fatty acid degradation_Homo sapiens_hsa000710.72908385
86Mineral absorption_Homo sapiens_hsa049780.72196792
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71853892
88Arginine biosynthesis_Homo sapiens_hsa002200.71021947
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.69989648
90Cysteine and methionine metabolism_Homo sapiens_hsa002700.69751830
91RNA polymerase_Homo sapiens_hsa030200.69400201
92Alcoholism_Homo sapiens_hsa050340.68728771
93Retinol metabolism_Homo sapiens_hsa008300.67225372
94African trypanosomiasis_Homo sapiens_hsa051430.67175318
95Steroid hormone biosynthesis_Homo sapiens_hsa001400.67000862
96Ovarian steroidogenesis_Homo sapiens_hsa049130.65492925
97Fatty acid elongation_Homo sapiens_hsa000620.65120395
98alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64985459
99Pyruvate metabolism_Homo sapiens_hsa006200.63180477
100Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62696445
101Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62102457
102Hedgehog signaling pathway_Homo sapiens_hsa043400.61942092
103Carbon metabolism_Homo sapiens_hsa012000.61461675
104Thyroid hormone synthesis_Homo sapiens_hsa049180.61450605
105Linoleic acid metabolism_Homo sapiens_hsa005910.60301679
106Arachidonic acid metabolism_Homo sapiens_hsa005900.55763940
107Steroid biosynthesis_Homo sapiens_hsa001000.55524080
108Dorso-ventral axis formation_Homo sapiens_hsa043200.54574591
109cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53876494
110Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53012314
111Bile secretion_Homo sapiens_hsa049760.51795117
112Tryptophan metabolism_Homo sapiens_hsa003800.51342314
113Hippo signaling pathway_Homo sapiens_hsa043900.51278981
114Cyanoamino acid metabolism_Homo sapiens_hsa004600.50155087
115Glutathione metabolism_Homo sapiens_hsa004800.48720545
116Purine metabolism_Homo sapiens_hsa002300.48689648
117Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47545853
118RNA degradation_Homo sapiens_hsa030180.46398098
119SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45577260
120Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.42689220
121Fatty acid biosynthesis_Homo sapiens_hsa000610.42639372
122Tight junction_Homo sapiens_hsa045300.42502144
123Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.40765065
124Type I diabetes mellitus_Homo sapiens_hsa049400.40729902
125Dilated cardiomyopathy_Homo sapiens_hsa054140.40567732
126Ras signaling pathway_Homo sapiens_hsa040140.39568416
127Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.37752097
128Phagosome_Homo sapiens_hsa041450.37289228
129Oocyte meiosis_Homo sapiens_hsa041140.35898465
130Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34362910
131Sphingolipid metabolism_Homo sapiens_hsa006000.33113766
132Homologous recombination_Homo sapiens_hsa034400.32302382
133Metabolic pathways_Homo sapiens_hsa011000.30559494
134Phospholipase D signaling pathway_Homo sapiens_hsa040720.29840767
135Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28209029
136Maturity onset diabetes of the young_Homo sapiens_hsa049500.28161765
137Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.27331711
138Phosphatidylinositol signaling system_Homo sapiens_hsa040700.26426638
139Circadian rhythm_Homo sapiens_hsa047100.25979939
140Wnt signaling pathway_Homo sapiens_hsa043100.23904507
141Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.20637100
142Rap1 signaling pathway_Homo sapiens_hsa040150.20608928
143Arginine and proline metabolism_Homo sapiens_hsa003300.20394501

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