KLF7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)4.66759933
2cell migration in hindbrain (GO:0021535)4.10763890
3presynaptic membrane assembly (GO:0097105)3.54342256
4detection of temperature stimulus involved in sensory perception of pain (GO:0050965)3.53668445
5detection of temperature stimulus involved in sensory perception (GO:0050961)3.53668445
6axon ensheathment in central nervous system (GO:0032291)3.34711714
7central nervous system myelination (GO:0022010)3.34711714
8positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.32349498
9cerebral cortex radially oriented cell migration (GO:0021799)3.31304573
10establishment of mitochondrion localization (GO:0051654)3.29699969
11neuron recognition (GO:0008038)3.28881473
12presynaptic membrane organization (GO:0097090)3.27684721
13detection of temperature stimulus (GO:0016048)3.18198181
14* dendrite morphogenesis (GO:0048813)3.17911591
15protein localization to synapse (GO:0035418)3.15995872
16vocalization behavior (GO:0071625)3.10922774
17pyrimidine nucleobase catabolic process (GO:0006208)3.09347252
18axonal fasciculation (GO:0007413)3.08715543
19layer formation in cerebral cortex (GO:0021819)3.02126581
20positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.01140536
21auditory behavior (GO:0031223)2.98939866
22neurofilament cytoskeleton organization (GO:0060052)2.97596555
23membrane assembly (GO:0071709)2.97144083
24neuronal action potential (GO:0019228)2.95427867
25negative regulation of microtubule polymerization (GO:0031115)2.95296088
26neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.94891610
27peripheral nervous system neuron development (GO:0048935)2.94738442
28postsynaptic membrane organization (GO:0001941)2.89662945
29neural tube formation (GO:0001841)2.86640916
30regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.86597003
31axon extension (GO:0048675)2.84946531
32regulation of synaptic vesicle exocytosis (GO:2000300)2.84676291
33synaptic vesicle exocytosis (GO:0016079)2.84230130
34glycosphingolipid biosynthetic process (GO:0006688)2.84130536
35neurotransmitter-gated ion channel clustering (GO:0072578)2.83848735
36gamma-aminobutyric acid transport (GO:0015812)2.83479675
37neuronal action potential propagation (GO:0019227)2.80317965
38regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.79539852
39negative regulation of protein localization to cell surface (GO:2000009)2.79233455
40negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.77892400
41epithelial cell differentiation involved in kidney development (GO:0035850)2.77589845
42ganglion development (GO:0061548)2.76532089
43negative regulation of dendrite morphogenesis (GO:0050774)2.76458392
44synaptic vesicle maturation (GO:0016188)2.75369904
45negative regulation of axonogenesis (GO:0050771)2.75180409
46regulation of axon extension involved in axon guidance (GO:0048841)2.74336102
47peptidyl-tyrosine autophosphorylation (GO:0038083)2.71678098
48neuron remodeling (GO:0016322)2.71602071
49behavioral response to nicotine (GO:0035095)2.71255095
50negative regulation of neurotransmitter transport (GO:0051589)2.69981934
51nerve growth factor signaling pathway (GO:0038180)2.69523739
52negative regulation of axon guidance (GO:1902668)2.68916721
53calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.68374485
54regulation of short-term neuronal synaptic plasticity (GO:0048172)2.68267655
55olfactory bulb development (GO:0021772)2.67663645
56synaptic transmission, glutamatergic (GO:0035249)2.67235450
57mitochondrion transport along microtubule (GO:0047497)2.66707047
58establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.66707047
59regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.66626007
60membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.64426802
61transmission of nerve impulse (GO:0019226)2.64217369
62calcium-mediated signaling using intracellular calcium source (GO:0035584)2.62871663
63establishment of nucleus localization (GO:0040023)2.62516825
64negative regulation of axon extension (GO:0030517)2.62104827
65long-chain fatty acid biosynthetic process (GO:0042759)2.61676645
66nucleobase catabolic process (GO:0046113)2.59959930
67dendritic spine morphogenesis (GO:0060997)2.59805706
68response to pain (GO:0048265)2.59309169
69negative chemotaxis (GO:0050919)2.59181384
70heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.58254102
71membrane depolarization during action potential (GO:0086010)2.58227387
72sympathetic nervous system development (GO:0048485)2.57139693
73positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.57038037
74synapse assembly (GO:0007416)2.56022673
75glutamate secretion (GO:0014047)2.55840376
76negative regulation of neurotransmitter secretion (GO:0046929)2.55246123
77axonogenesis (GO:0007409)2.54676515
78urinary tract smooth muscle contraction (GO:0014848)2.54003275
79negative regulation of calcium ion transport into cytosol (GO:0010523)2.53824534
80neuronal ion channel clustering (GO:0045161)2.53274883
81response to auditory stimulus (GO:0010996)2.52920568
82regulation of synaptic transmission, glutamatergic (GO:0051966)2.52526560
83activated T cell proliferation (GO:0050798)2.50377243
84positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.49986957
85negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.49919499
86glial cell proliferation (GO:0014009)2.49804543
87positive regulation of potassium ion transmembrane transport (GO:1901381)2.49191703
88tachykinin receptor signaling pathway (GO:0007217)2.48827044
89central nervous system projection neuron axonogenesis (GO:0021952)2.48144024
90retinal ganglion cell axon guidance (GO:0031290)2.47821198
91regulation of cell communication by electrical coupling (GO:0010649)2.47611582
92enteric nervous system development (GO:0048484)2.45676917
93regulation of respiratory system process (GO:0044065)2.45491196
94regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.45189859
95neuron projection extension (GO:1990138)2.44403584
96proline transport (GO:0015824)2.44129832
97limb bud formation (GO:0060174)2.43516926
98regulation of collateral sprouting (GO:0048670)2.43260213
99ionotropic glutamate receptor signaling pathway (GO:0035235)2.42819154
100regulation of extent of cell growth (GO:0061387)2.42375245
101myelination (GO:0042552)2.42180393
102positive regulation of action potential (GO:0045760)2.41881520
103neuromuscular synaptic transmission (GO:0007274)2.41825851
104synapse organization (GO:0050808)2.40675940
105negative regulation of axon extension involved in axon guidance (GO:0048843)2.40421046
106head development (GO:0060322)2.40117517
107forebrain neuron differentiation (GO:0021879)2.39592316
108regulation of synapse assembly (GO:0051963)2.38967476
109negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.38760580
110negative regulation of translation, ncRNA-mediated (GO:0040033)2.38760580
111regulation of translation, ncRNA-mediated (GO:0045974)2.38760580
112axon ensheathment (GO:0008366)2.38718786
113ensheathment of neurons (GO:0007272)2.38718786
114dendrite development (GO:0016358)2.37476688
115glutamate receptor signaling pathway (GO:0007215)2.37420919
116regulation of amyloid precursor protein catabolic process (GO:1902991)2.37246155
117regulation of respiratory gaseous exchange (GO:0043576)2.36948527
118behavioral response to ethanol (GO:0048149)2.36925046
119neuron-neuron synaptic transmission (GO:0007270)2.36447840
120positive regulation of synaptic transmission, GABAergic (GO:0032230)2.36396797
121central nervous system neuron axonogenesis (GO:0021955)2.36271324
122organelle transport along microtubule (GO:0072384)2.36226205
123hippocampus development (GO:0021766)2.36071824
124regulation of feeding behavior (GO:0060259)2.35563505
125positive regulation of synapse assembly (GO:0051965)2.35405100
126negative regulation of dendrite development (GO:2000171)2.35394384
127startle response (GO:0001964)2.34715923
128regulation of neurotransmitter secretion (GO:0046928)2.34525450
129regulation of microtubule polymerization (GO:0031113)2.34187182
130cerebral cortex cell migration (GO:0021795)2.34043047
131regulation of glutamate receptor signaling pathway (GO:1900449)2.33744701
132regulation of axon extension (GO:0030516)2.33391084
133behavioral response to pain (GO:0048266)2.33064230
134innervation (GO:0060384)2.33044987
135negative regulation of synaptic transmission, GABAergic (GO:0032229)2.31541652
136locomotory exploration behavior (GO:0035641)2.31431806
137regulation of synapse structural plasticity (GO:0051823)2.31342699
138regulation of synaptic vesicle transport (GO:1902803)2.31072834
139cardiac ventricle formation (GO:0003211)2.30006182
140spinal cord development (GO:0021510)2.30006045
141regulation of axonogenesis (GO:0050770)2.29988568
142adult walking behavior (GO:0007628)2.29974912
143regulation of action potential (GO:0098900)2.29532256
144mating behavior (GO:0007617)2.29324802
145exploration behavior (GO:0035640)2.29129397
146regulation of axon guidance (GO:1902667)2.28596680
147regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.28412507
148homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.28172486

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.16090960
2GBX2_23144817_ChIP-Seq_PC3_Human3.28086923
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.70947698
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.70259042
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.54427537
6TAF15_26573619_Chip-Seq_HEK293_Human2.44202557
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40584177
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40584177
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36767852
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.34060652
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.33190177
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.31112390
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.26094052
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.22222394
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.22106415
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.13952364
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.04646056
18* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.97795171
19AR_21572438_ChIP-Seq_LNCaP_Human1.96275966
20SMAD_19615063_ChIP-ChIP_OVARY_Human1.96143246
21RNF2_27304074_Chip-Seq_ESCs_Mouse1.91615545
22EZH2_27294783_Chip-Seq_ESCs_Mouse1.89332366
23ZFP57_27257070_Chip-Seq_ESCs_Mouse1.87303455
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.85299738
25CDX2_19796622_ChIP-Seq_MESCs_Mouse1.83858387
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.83138782
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.81821297
28* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.76238237
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70657516
30* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64951803
31PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.64193438
32* P300_19829295_ChIP-Seq_ESCs_Human1.64174462
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.62543725
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.62085863
35* REST_21632747_ChIP-Seq_MESCs_Mouse1.60248220
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.59716449
37* SMAD4_21799915_ChIP-Seq_A2780_Human1.57509545
38DROSHA_22980978_ChIP-Seq_HELA_Human1.55415221
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.54357131
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.53734051
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.53658409
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.53582124
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53430598
44* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.51456512
45ZNF217_24962896_ChIP-Seq_MCF-7_Human1.50290505
46CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.46178746
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.43294088
48* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41981657
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39859915
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39811142
51AHR_22903824_ChIP-Seq_MCF-7_Human1.38775316
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38538156
53* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37523423
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.34076946
55RNF2_27304074_Chip-Seq_NSC_Mouse1.32802022
56VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.26722433
57VDR_22108803_ChIP-Seq_LS180_Human1.26466436
58ARNT_22903824_ChIP-Seq_MCF-7_Human1.25391998
59* STAT3_23295773_ChIP-Seq_U87_Human1.25350545
60* EP300_21415370_ChIP-Seq_HL-1_Mouse1.24177971
61ER_23166858_ChIP-Seq_MCF-7_Human1.23179051
62IGF1R_20145208_ChIP-Seq_DFB_Human1.22084022
63IKZF1_21737484_ChIP-ChIP_HCT116_Human1.21214809
64ZNF274_21170338_ChIP-Seq_K562_Hela1.21135111
65* NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.21071757
66* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19855610
67NRF2_20460467_ChIP-Seq_MEFs_Mouse1.19794333
68NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.19794333
69AR_25329375_ChIP-Seq_VCAP_Human1.19473936
70KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18270126
71GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15037459
72SOX2_21211035_ChIP-Seq_LN229_Gbm1.14789549
73PRDM14_20953172_ChIP-Seq_ESCs_Human1.14722023
74TCF4_18268006_ChIP-ChIP_LS174T_Human1.14377707
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14084012
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13920334
77ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.13864276
78* REST_18959480_ChIP-ChIP_MESCs_Mouse1.13597883
79RING1B_27294783_Chip-Seq_NPCs_Mouse1.11698220
80POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11531149
81TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11531149
82TP53_18474530_ChIP-ChIP_U2OS_Human1.11223509
83* RUNX2_22187159_ChIP-Seq_PCA_Human1.10575975
84TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.10174726
85RING1B_27294783_Chip-Seq_ESCs_Mouse1.09165026
86RARB_27405468_Chip-Seq_BRAIN_Mouse1.08940841
87P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08738402
88CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.07870097
89* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07553330
90TP53_16413492_ChIP-PET_HCT116_Human1.06866480
91NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06565477
92* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05335966
93FLI1_21867929_ChIP-Seq_TH2_Mouse1.05025273
94EWS_26573619_Chip-Seq_HEK293_Human1.04830556
95* TCF4_23295773_ChIP-Seq_U87_Human1.04819610
96* SMAD3_21741376_ChIP-Seq_HESCs_Human1.03955027
97IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.03520307
98CBP_20019798_ChIP-Seq_JUKART_Human1.03520307
99* NANOG_18555785_Chip-Seq_ESCs_Mouse1.03209375
100* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02216767
101MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02132899
102* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01926463
103* SMAD4_21741376_ChIP-Seq_HESCs_Human1.01731169
104BCAT_22108803_ChIP-Seq_LS180_Human1.01223066
105YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01205826
106LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99618528
107* JUN_21703547_ChIP-Seq_K562_Human0.96438476
108* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95396368
109FUS_26573619_Chip-Seq_HEK293_Human0.95383480
110MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93826010
111* E2F1_18555785_Chip-Seq_ESCs_Mouse0.93486738
112KDM2B_26808549_Chip-Seq_REH_Human0.93391076
113TRIM28_21343339_ChIP-Seq_HEK293_Human0.93025328
114* CMYC_18555785_Chip-Seq_ESCs_Mouse0.91011190

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002735_abnormal_chemical_nociception4.16329216
2* MP0004270_analgesia3.73043672
3MP0001968_abnormal_touch/_nociception3.68093490
4MP0004859_abnormal_synaptic_plasticity3.23212724
5MP0003880_abnormal_central_pattern3.05296092
6MP0006276_abnormal_autonomic_nervous3.02460785
7* MP0002734_abnormal_mechanical_nocicepti3.02258715
8MP0002736_abnormal_nociception_after2.98487092
9MP0002733_abnormal_thermal_nociception2.88084983
10MP0005423_abnormal_somatic_nervous2.68776191
11MP0003635_abnormal_synaptic_transmissio2.57367323
12MP0001970_abnormal_pain_threshold2.55781566
13* MP0000778_abnormal_nervous_system2.51935163
14MP0004858_abnormal_nervous_system2.33627524
15MP0001986_abnormal_taste_sensitivity2.25278558
16MP0009745_abnormal_behavioral_response2.20305758
17MP0002272_abnormal_nervous_system2.12889176
18MP0002063_abnormal_learning/memory/cond2.12303559
19* MP0002184_abnormal_innervation2.07619741
20MP0002572_abnormal_emotion/affect_behav2.05845409
21MP0001486_abnormal_startle_reflex2.01793246
22MP0002064_seizures2.00859034
23MP0001188_hyperpigmentation2.00276375
24MP0001440_abnormal_grooming_behavior1.97870053
25MP0005171_absent_coat_pigmentation1.95013576
26MP0009046_muscle_twitch1.89547286
27MP0002067_abnormal_sensory_capabilities1.89264963
28MP0000920_abnormal_myelination1.88364384
29MP0004742_abnormal_vestibular_system1.71801144
30MP0010386_abnormal_urinary_bladder1.71216633
31MP0003121_genomic_imprinting1.71064469
32MP0005409_darkened_coat_color1.69909723
33MP0003724_increased_susceptibility_to1.68601516
34MP0001905_abnormal_dopamine_level1.67547558
35MP0001984_abnormal_olfaction1.64324297
36MP0000955_abnormal_spinal_cord1.55039517
37MP0005187_abnormal_penis_morphology1.54365917
38MP0005394_taste/olfaction_phenotype1.52922867
39MP0005499_abnormal_olfactory_system1.52922867
40MP0002751_abnormal_autonomic_nervous1.48379119
41MP0000516_abnormal_urinary_system1.44632103
42MP0005367_renal/urinary_system_phenotyp1.44632103
43* MP0002882_abnormal_neuron_morphology1.43193889
44MP0002557_abnormal_social/conspecific_i1.42831950
45MP0004924_abnormal_behavior1.40219153
46MP0005386_behavior/neurological_phenoty1.40219153
47MP0004811_abnormal_neuron_physiology1.38776624
48MP0001501_abnormal_sleep_pattern1.35860054
49MP0001529_abnormal_vocalization1.33619435
50MP0005645_abnormal_hypothalamus_physiol1.33299759
51MP0003634_abnormal_glial_cell1.31870306
52MP0002928_abnormal_bile_duct1.30541216
53MP0001299_abnormal_eye_distance/1.27907575
54MP0002822_catalepsy1.25311100
55MP0003329_amyloid_beta_deposits1.22833385
56MP0008569_lethality_at_weaning1.21920001
57MP0000372_irregular_coat_pigmentation1.17461882
58MP0003890_abnormal_embryonic-extraembry1.12206590
59MP0009379_abnormal_foot_pigmentation1.11492416
60MP0002066_abnormal_motor_capabilities/c1.11052224
61MP0002909_abnormal_adrenal_gland1.10254323
62MP0004085_abnormal_heartbeat1.09608707
63MP0004145_abnormal_muscle_electrophysio1.08342984
64* MP0002752_abnormal_somatic_nervous1.08102617
65MP0003690_abnormal_glial_cell1.07035748
66MP0000049_abnormal_middle_ear1.06412332
67MP0004142_abnormal_muscle_tone1.05539462
68MP0003755_abnormal_palate_morphology1.04286458
69MP0000751_myopathy1.03124868
70MP0004885_abnormal_endolymph1.02400740
71MP0000569_abnormal_digit_pigmentation1.01883898
72MP0002638_abnormal_pupillary_reflex0.99363576
73MP0000427_abnormal_hair_cycle0.98578139
74MP0006054_spinal_hemorrhage0.96778265
75MP0005275_abnormal_skin_tensile0.96691075
76MP0003631_nervous_system_phenotype0.95216447
77MP0003633_abnormal_nervous_system0.94362538
78MP0003183_abnormal_peptide_metabolism0.93965355
79* MP0002152_abnormal_brain_morphology0.93809622
80MP0001963_abnormal_hearing_physiology0.93698016
81MP0000015_abnormal_ear_pigmentation0.92877495
82MP0005084_abnormal_gallbladder_morpholo0.92588378
83MP0001485_abnormal_pinna_reflex0.91613537
84MP0002229_neurodegeneration0.91091394
85MP0003935_abnormal_craniofacial_develop0.85879031
86MP0001502_abnormal_circadian_rhythm0.85359270
87MP0004484_altered_response_of0.85344903
88MP0000538_abnormal_urinary_bladder0.85210269
89MP0004133_heterotaxia0.85099870
90MP0002277_abnormal_respiratory_mucosa0.83753301
91MP0005646_abnormal_pituitary_gland0.83206283
92MP0002234_abnormal_pharynx_morphology0.82886652
93* MP0002069_abnormal_eating/drinking_beha0.82849275
94MP0003632_abnormal_nervous_system0.82316408
95MP0002163_abnormal_gland_morphology0.81115885
96MP0002332_abnormal_exercise_endurance0.80569381
97MP0004883_abnormal_blood_vessel0.80379558
98MP0003221_abnormal_cardiomyocyte_apopto0.80038275
99MP0001177_atelectasis0.79832596
100MP0002081_perinatal_lethality0.79646101
101MP0001879_abnormal_lymphatic_vessel0.78661911
102MP0005623_abnormal_meninges_morphology0.75888027
103MP0000631_abnormal_neuroendocrine_gland0.75648485
104MP0003828_pulmonary_edema0.75032246
105MP0009780_abnormal_chondrocyte_physiolo0.74083650
106MP0003137_abnormal_impulse_conducting0.73820985
107MP0000026_abnormal_inner_ear0.73520623
108MP0005195_abnormal_posterior_eye0.73200888
109MP0001270_distended_abdomen0.72915032
110MP0001348_abnormal_lacrimal_gland0.72061362
111MP0010368_abnormal_lymphatic_system0.70868388
112MP0005248_abnormal_Harderian_gland0.68973444
113MP0000013_abnormal_adipose_tissue0.68729897
114MP0003122_maternal_imprinting0.68546910
115* MP0003948_abnormal_gas_homeostasis0.68325441
116MP0005503_abnormal_tendon_morphology0.67912843
117MP0003787_abnormal_imprinting0.67038440
118* MP0003861_abnormal_nervous_system0.66158972
119MP0003136_yellow_coat_color0.65908998
120MP0008874_decreased_physiological_sensi0.65710944
121MP0002972_abnormal_cardiac_muscle0.65038094
122MP0002102_abnormal_ear_morphology0.60631803
123MP0003385_abnormal_body_wall0.59671581
124MP0003045_fibrosis0.59035210
125* MP0001943_abnormal_respiration0.58511182
126MP0008789_abnormal_olfactory_epithelium0.58472699
127MP0004510_myositis0.57447241
128MP0000579_abnormal_nail_morphology0.56450493
129MP0003303_peritoneal_inflammation0.55791361
130MP0005379_endocrine/exocrine_gland_phen0.54592522
131MP0002837_dystrophic_cardiac_calcinosis0.52833607
132MP0000534_abnormal_ureter_morphology0.52548564
133MP0005551_abnormal_eye_electrophysiolog0.52018886

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.91642641
2Ulnar claw (HP:0001178)4.24223066
3Insidious onset (HP:0003587)3.87393335
4Termporal pattern (HP:0011008)3.87393335
5Abnormality of the corticospinal tract (HP:0002492)3.79046276
6Hypothermia (HP:0002045)3.70283005
7Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.59169459
8Degeneration of the lateral corticospinal tracts (HP:0002314)3.59169459
9Progressive cerebellar ataxia (HP:0002073)3.58576473
10Limb dystonia (HP:0002451)3.57355687
11Action tremor (HP:0002345)3.55683799
12Focal seizures (HP:0007359)3.52522726
13Atonic seizures (HP:0010819)3.38082243
14Lissencephaly (HP:0001339)3.35570679
15Focal motor seizures (HP:0011153)3.31711955
16Supranuclear gaze palsy (HP:0000605)3.22656535
17Sensory axonal neuropathy (HP:0003390)3.13475037
18Neurofibrillary tangles (HP:0002185)3.05720985
19Amyotrophic lateral sclerosis (HP:0007354)3.02068457
20Pachygyria (HP:0001302)3.00512568
21Febrile seizures (HP:0002373)2.94140654
22Exotropia (HP:0000577)2.88087795
23Ankle clonus (HP:0011448)2.78758163
24Steppage gait (HP:0003376)2.78057674
25Amblyopia (HP:0000646)2.77570445
26Peripheral hypomyelination (HP:0007182)2.75965498
27Epileptic encephalopathy (HP:0200134)2.74118705
28Aplasia/Hypoplasia of the brainstem (HP:0007362)2.61890025
29Hypoplasia of the brainstem (HP:0002365)2.61890025
30Segmental peripheral demyelination/remyelination (HP:0003481)2.58213914
31Parakeratosis (HP:0001036)2.55811283
32Onion bulb formation (HP:0003383)2.51768513
33Obstructive sleep apnea (HP:0002870)2.49385967
34Decreased number of peripheral myelinated nerve fibers (HP:0003380)2.49058992
35Abnormal hair whorl (HP:0010721)2.48351429
36Pheochromocytoma (HP:0002666)2.44754694
37Submucous cleft hard palate (HP:0000176)2.39642672
38Akinesia (HP:0002304)2.36232764
39Spastic gait (HP:0002064)2.33148014
40Oligodactyly (hands) (HP:0001180)2.32529805
41Cerebral inclusion bodies (HP:0100314)2.31872571
42Chin dimple (HP:0010751)2.29794885
43Abnormality of the lower motor neuron (HP:0002366)2.29333444
44Foot dorsiflexor weakness (HP:0009027)2.29287198
45Atrophic scars (HP:0001075)2.25529186
46Broad-based gait (HP:0002136)2.23882896
47Medial flaring of the eyebrow (HP:0010747)2.23826415
48Protruding tongue (HP:0010808)2.21512199
49Megalencephaly (HP:0001355)2.21181627
50Nephrogenic diabetes insipidus (HP:0009806)2.19932723
51J-shaped sella turcica (HP:0002680)2.18574384
52Agitation (HP:0000713)2.17704053
53Bradycardia (HP:0001662)2.17131166
54Palpebral edema (HP:0100540)2.16433310
55Lower limb muscle weakness (HP:0007340)2.16246864
56Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.15774714
57Short 4th metacarpal (HP:0010044)2.15774714
58Hip dysplasia (HP:0001385)2.15740993
59Congenital primary aphakia (HP:0007707)2.15671535
60Sleep apnea (HP:0010535)2.15168414
61Hammertoe (HP:0001765)2.14045319
62Split foot (HP:0001839)2.12669870
63Mutism (HP:0002300)2.12615564
64Dysmetria (HP:0001310)2.10461795
65Abnormality of the foot musculature (HP:0001436)2.09052802
66Papillary thyroid carcinoma (HP:0002895)2.08708660
67Retinal dysplasia (HP:0007973)2.08705517
68Epileptiform EEG discharges (HP:0011182)2.07855227
69Hypoplastic nipples (HP:0002557)2.07724044
70Excessive salivation (HP:0003781)2.07605102
71Drooling (HP:0002307)2.07605102
72Hypsarrhythmia (HP:0002521)2.07116236
73Autoamputation (HP:0001218)2.07111747
74EEG with generalized epileptiform discharges (HP:0011198)2.06852043
75Urinary bladder sphincter dysfunction (HP:0002839)2.06827286
76Neuroendocrine neoplasm (HP:0100634)2.06121605
77Morphological abnormality of the middle ear (HP:0008609)2.05257564
78Failure to thrive in infancy (HP:0001531)2.04702377
79Hyperventilation (HP:0002883)2.04603395
80Hepatoblastoma (HP:0002884)2.02213797
81Labial hypoplasia (HP:0000066)2.02076809
82Peritonitis (HP:0002586)2.00622589
83Absence seizures (HP:0002121)2.00071698
84Overgrowth (HP:0001548)1.99565267
85Truncal ataxia (HP:0002078)1.99343863
86Esotropia (HP:0000565)1.98638653
87Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.98600388
88Dialeptic seizures (HP:0011146)1.98224268
89Intestinal atresia (HP:0011100)1.97616742
90Abnormal autonomic nervous system physiology (HP:0012332)1.97187315
91Aqueductal stenosis (HP:0002410)1.95919109
92Visual hallucinations (HP:0002367)1.95720900
93Abnormality of salivation (HP:0100755)1.94118416
94Broad ribs (HP:0000885)1.93222857
95Generalized tonic-clonic seizures (HP:0002069)1.92499712
96Progressive inability to walk (HP:0002505)1.92254482
97Absent speech (HP:0001344)1.92215710
98Thickened helices (HP:0000391)1.92155683
99Inability to walk (HP:0002540)1.91448627
100Gaze-evoked nystagmus (HP:0000640)1.89220473
101Intellectual disability, severe (HP:0010864)1.88038789
102Blue irides (HP:0000635)1.87730563
103Polyphagia (HP:0002591)1.87716655
104Decreased motor nerve conduction velocity (HP:0003431)1.87428991
105Genital tract atresia (HP:0001827)1.85710418
106Urinary urgency (HP:0000012)1.84614576
107Diplopia (HP:0000651)1.84363125
108Abnormality of binocular vision (HP:0011514)1.84363125
109Mild short stature (HP:0003502)1.83086369
110Adactyly (HP:0009776)1.82277408
111Wrist flexion contracture (HP:0001239)1.82046652
112Myotonia (HP:0002486)1.82042996
113Cortical dysplasia (HP:0002539)1.81623315
114Abnormality of the intervertebral disk (HP:0005108)1.81351299
115Short foot (HP:0001773)1.80636964
116Gait imbalance (HP:0002141)1.80587466
117Abnormality of pain sensation (HP:0010832)1.79850444
118Impaired pain sensation (HP:0007328)1.79850444
119Widely spaced teeth (HP:0000687)1.79775566
120Genetic anticipation (HP:0003743)1.79617170
121Polymicrogyria (HP:0002126)1.79475753
122Inappropriate behavior (HP:0000719)1.78656836
123Hypoplasia of the corpus callosum (HP:0002079)1.77815859
124Distal sensory impairment (HP:0002936)1.77389481
125Scanning speech (HP:0002168)1.75499959
126Specific learning disability (HP:0001328)1.75129690
127Prolonged QT interval (HP:0001657)1.74793989
128Thyroid carcinoma (HP:0002890)1.74766192
129Spastic tetraplegia (HP:0002510)1.74437164
130Postural tremor (HP:0002174)1.73939257
131Vaginal atresia (HP:0000148)1.71807710
132Hypoventilation (HP:0002791)1.70652573
133Tented upper lip vermilion (HP:0010804)1.70326119
134Pulmonic stenosis (HP:0001642)1.70161635
135Hemiparesis (HP:0001269)1.69875853
136Anxiety (HP:0000739)1.68973638
137Pancreatic cysts (HP:0001737)1.68852784
138Papilledema (HP:0001085)1.67429498
139Xerostomia (HP:0000217)1.67145045
140Delayed gross motor development (HP:0002194)1.67012349
141True hermaphroditism (HP:0010459)1.66465939
142Hyperthyroidism (HP:0000836)1.65746905
143Poor coordination (HP:0002370)1.65734670
144Aplasia involving bones of the extremities (HP:0009825)1.65704082
145Aplasia involving bones of the upper limbs (HP:0009823)1.65704082
146Aplasia of the phalanges of the hand (HP:0009802)1.65704082
147Cupped ear (HP:0000378)1.65462046
148Pancreatic fibrosis (HP:0100732)1.64892953
149Vertebral arch anomaly (HP:0008438)1.64658388
150Abnormal eating behavior (HP:0100738)1.64609064
151Cutaneous finger syndactyly (HP:0010554)1.64413192
152Optic nerve hypoplasia (HP:0000609)1.64365765
153Narrow nasal bridge (HP:0000446)1.63426275
154Aplasia/Hypoplasia of the lens (HP:0008063)1.63143461
155Hemiplegia (HP:0002301)1.63025742
156Narrow forehead (HP:0000341)1.62672775
157Impaired vibration sensation in the lower limbs (HP:0002166)1.61771385
158Choroideremia (HP:0001139)1.60111101

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.08381968
2CASK3.02022375
3FRK2.74642597
4NTRK12.72237108
5MAPK132.48128260
6GRK52.43859242
7NTRK32.34685690
8STK392.29305929
9MAP4K22.15483484
10MAP3K92.07161140
11PHKG12.02298634
12PHKG22.02298634
13MINK12.02056161
14WNK31.92500526
15DYRK21.89277423
16GRK71.83855432
17LIMK11.73415615
18TNIK1.69527474
19MAP2K71.63068942
20PNCK1.57947740
21MAP3K41.54650775
22NTRK21.53663239
23BCR1.44938209
24SGK2231.42768846
25SGK4941.42768846
26UHMK11.40429714
27OXSR11.37152969
28PAK61.32921858
29BMPR1B1.31753040
30SIK21.29402701
31PKN11.27427878
32CSNK1G21.22214334
33DAPK21.21361023
34PRPF4B1.20736721
35TRIM281.18966262
36PLK21.17946620
37MUSK1.16891840
38RET1.16507967
39CDK51.13671754
40RIPK41.13174677
41KSR21.10314796
42CSNK1A1L1.10079139
43PRKCE1.09528687
44CSNK1G31.08547706
45PTK2B1.07801351
46MAP3K21.04932619
47AKT31.04850054
48WNK11.03440795
49MARK21.02967452
50EPHB11.01551605
51KSR11.00394564
52FGR0.99237928
53ERBB30.98999153
54PINK10.97095372
55SGK20.96557677
56FGFR20.95735581
57WNK40.95234982
58MAPKAPK50.93513372
59ARAF0.92503680
60MAP3K120.91729358
61DYRK1B0.90920649
62CAMK2A0.90669849
63EPHB20.89147755
64TAOK30.87974807
65ADRBK10.87204473
66BRD40.86249815
67SIK30.84685141
68CAMK2B0.82434375
69LATS20.81374185
70PAK30.80542065
71CAMK1G0.80150817
72DYRK30.77621654
73CDK140.77415457
74MAP2K40.76724685
75BMPR20.74797054
76YES10.73735094
77RPS6KA20.73663803
78CSNK1G10.73234350
79ROCK20.73129952
80EPHA30.72204868
81EPHA40.71695835
82CAMK2D0.69886921
83BLK0.66264900
84PRKD20.65711883
85DYRK1A0.65689509
86STK380.65239300
87CAMK40.64366594
88TIE10.63454268
89IRAK20.62636348
90FER0.61638543
91TAOK10.60975031
92MAPK120.60931285
93MAP3K60.57823133
94RPS6KA40.57665271
95FES0.56818007
96DMPK0.56759915
97SGK30.55753439
98CAMKK20.55449780
99ADRBK20.54519838
100MAPK70.54451852
101IRAK10.53942092
102CDK180.53195063
103INSRR0.52923176
104PRKG10.51943737
105LMTK20.51356096
106ROCK10.51299442
107CDK150.50419165
108MATK0.49877801
109PRKCG0.49694845
110MAP2K10.49433064
111PDGFRB0.49272796
112STK110.47728449
113FYN0.47087834
114SGK10.46379683
115MET0.45814326
116MARK30.45583672
117NEK60.45191481
118TGFBR20.44734133
119CDK190.44514511
120PRKCH0.44509145
121PRKCZ0.44150057
122ERBB20.44087438
123NLK0.41394932
124HCK0.41151938
125CAMKK10.38809603
126MAP3K70.37045341
127PRKD10.37001985
128ABL10.35628627
129CAMK10.35507459
130MAPK80.33127777
131CDK30.32654872
132EGFR0.32068384

Predicted pathways (KEGG)

RankGene SetZ-score
1Axon guidance_Homo sapiens_hsa043601.92387197
2Serotonergic synapse_Homo sapiens_hsa047261.88768452
3Glutamatergic synapse_Homo sapiens_hsa047241.81875334
4Olfactory transduction_Homo sapiens_hsa047401.81216184
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.80449192
6Synaptic vesicle cycle_Homo sapiens_hsa047211.75989926
7Nicotine addiction_Homo sapiens_hsa050331.73711788
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.72556791
9Cholinergic synapse_Homo sapiens_hsa047251.70752850
10Circadian entrainment_Homo sapiens_hsa047131.66701560
11Taste transduction_Homo sapiens_hsa047421.66482181
12Morphine addiction_Homo sapiens_hsa050321.62752131
13Dopaminergic synapse_Homo sapiens_hsa047281.62490243
14Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.56884908
15Dorso-ventral axis formation_Homo sapiens_hsa043201.56791281
16GABAergic synapse_Homo sapiens_hsa047271.54142296
17Long-term depression_Homo sapiens_hsa047301.47454421
18Long-term potentiation_Homo sapiens_hsa047201.46840110
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.37053996
20Salivary secretion_Homo sapiens_hsa049701.30962236
21Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.30062802
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.29215176
23Insulin secretion_Homo sapiens_hsa049111.27063253
24Renin secretion_Homo sapiens_hsa049241.26595924
25Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26580745
26Steroid biosynthesis_Homo sapiens_hsa001001.26083617
27Amphetamine addiction_Homo sapiens_hsa050311.23327089
28Gap junction_Homo sapiens_hsa045401.23225574
29GnRH signaling pathway_Homo sapiens_hsa049121.22651511
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20886464
31ErbB signaling pathway_Homo sapiens_hsa040121.18988320
32Cocaine addiction_Homo sapiens_hsa050301.18774496
33Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.18390275
34Circadian rhythm_Homo sapiens_hsa047101.16018449
35Ether lipid metabolism_Homo sapiens_hsa005651.13917386
36Oxytocin signaling pathway_Homo sapiens_hsa049211.13590868
37Gastric acid secretion_Homo sapiens_hsa049711.13186234
38Renal cell carcinoma_Homo sapiens_hsa052111.11502428
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.08031724
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03878847
41Ras signaling pathway_Homo sapiens_hsa040141.02181163
42Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01483470
43Sphingolipid signaling pathway_Homo sapiens_hsa040710.99444091
44Phospholipase D signaling pathway_Homo sapiens_hsa040720.98046079
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.96526769
46Melanogenesis_Homo sapiens_hsa049160.95974164
47Glioma_Homo sapiens_hsa052140.95485057
48Calcium signaling pathway_Homo sapiens_hsa040200.94885542
49Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.94255830
50Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94181975
51Estrogen signaling pathway_Homo sapiens_hsa049150.93474648
52cAMP signaling pathway_Homo sapiens_hsa040240.93346688
53Collecting duct acid secretion_Homo sapiens_hsa049660.92385124
54MAPK signaling pathway_Homo sapiens_hsa040100.91015525
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.88129681
56Neurotrophin signaling pathway_Homo sapiens_hsa047220.87924512
57Choline metabolism in cancer_Homo sapiens_hsa052310.86323610
58Rheumatoid arthritis_Homo sapiens_hsa053230.84604458
59Regulation of autophagy_Homo sapiens_hsa041400.83812621
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83229080
61Type II diabetes mellitus_Homo sapiens_hsa049300.82982587
62Endometrial cancer_Homo sapiens_hsa052130.82507033
63Cardiac muscle contraction_Homo sapiens_hsa042600.81938762
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81151226
65Dilated cardiomyopathy_Homo sapiens_hsa054140.81067760
66Rap1 signaling pathway_Homo sapiens_hsa040150.80710730
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80089151
68VEGF signaling pathway_Homo sapiens_hsa043700.80018321
69FoxO signaling pathway_Homo sapiens_hsa040680.79179621
70Phototransduction_Homo sapiens_hsa047440.78854423
71Inositol phosphate metabolism_Homo sapiens_hsa005620.76460260
72African trypanosomiasis_Homo sapiens_hsa051430.76262436
73Vibrio cholerae infection_Homo sapiens_hsa051100.75981843
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.75260524
75Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.74822238
76Adherens junction_Homo sapiens_hsa045200.74782170
77Phagosome_Homo sapiens_hsa041450.74706897
78Melanoma_Homo sapiens_hsa052180.74464501
79Chemokine signaling pathway_Homo sapiens_hsa040620.73722344
80Salmonella infection_Homo sapiens_hsa051320.73131006
81Endocytosis_Homo sapiens_hsa041440.72989633
82ECM-receptor interaction_Homo sapiens_hsa045120.72368903
83Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71664469
84Ovarian steroidogenesis_Homo sapiens_hsa049130.70799328
85Alzheimers disease_Homo sapiens_hsa050100.69678707
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67922212
87Osteoclast differentiation_Homo sapiens_hsa043800.67798372
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.66567662
89Colorectal cancer_Homo sapiens_hsa052100.66130783
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.65740914
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65476065
92Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.65150209
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64244859
94Pancreatic secretion_Homo sapiens_hsa049720.63822628
95Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62656608
96Sphingolipid metabolism_Homo sapiens_hsa006000.62598590
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62375039
98Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62338126
99Wnt signaling pathway_Homo sapiens_hsa043100.61595419
100AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61101778
101Amoebiasis_Homo sapiens_hsa051460.60825350
102Prolactin signaling pathway_Homo sapiens_hsa049170.59972831
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59259413
104Hippo signaling pathway_Homo sapiens_hsa043900.56707171
105Notch signaling pathway_Homo sapiens_hsa043300.56697461
106Tight junction_Homo sapiens_hsa045300.56633165
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.56025933
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55678597
109mTOR signaling pathway_Homo sapiens_hsa041500.55103002
110Oxidative phosphorylation_Homo sapiens_hsa001900.54689493
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54679429
112T cell receptor signaling pathway_Homo sapiens_hsa046600.54609755
113Hedgehog signaling pathway_Homo sapiens_hsa043400.54253597
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53393711
115Focal adhesion_Homo sapiens_hsa045100.53189603
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.51239725
117Jak-STAT signaling pathway_Homo sapiens_hsa046300.50912075
118PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50724970
119Platelet activation_Homo sapiens_hsa046110.50536992
120Pancreatic cancer_Homo sapiens_hsa052120.50239072
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49426663
122Tuberculosis_Homo sapiens_hsa051520.49351165

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »