KIR3DX1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.54161472
2fucose catabolic process (GO:0019317)4.61404336
3L-fucose metabolic process (GO:0042354)4.61404336
4L-fucose catabolic process (GO:0042355)4.61404336
5DNA deamination (GO:0045006)4.43437054
6indolalkylamine metabolic process (GO:0006586)4.19567875
7response to pheromone (GO:0019236)4.10693256
8detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.07089900
9tryptophan catabolic process (GO:0006569)4.01499375
10indole-containing compound catabolic process (GO:0042436)4.01499375
11indolalkylamine catabolic process (GO:0046218)4.01499375
12detection of light stimulus involved in sensory perception (GO:0050962)3.94002000
13detection of light stimulus involved in visual perception (GO:0050908)3.94002000
14kynurenine metabolic process (GO:0070189)3.72004287
15cellular ketone body metabolic process (GO:0046950)3.60524554
16tryptophan metabolic process (GO:0006568)3.39856486
17ketone body metabolic process (GO:1902224)3.22646963
18water-soluble vitamin biosynthetic process (GO:0042364)3.21708409
19reflex (GO:0060004)3.10458083
20indole-containing compound metabolic process (GO:0042430)3.09930080
21protein polyglutamylation (GO:0018095)3.04493362
22piRNA metabolic process (GO:0034587)3.01779022
23epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.99359032
24gamma-aminobutyric acid transport (GO:0015812)2.98694077
25signal peptide processing (GO:0006465)2.98382661
26cytidine deamination (GO:0009972)2.96494876
27cytidine metabolic process (GO:0046087)2.96494876
28cytidine catabolic process (GO:0006216)2.96494876
29axoneme assembly (GO:0035082)2.95223996
30neural tube formation (GO:0001841)2.94825482
31amine catabolic process (GO:0009310)2.93952082
32cellular biogenic amine catabolic process (GO:0042402)2.93952082
33cilium or flagellum-dependent cell motility (GO:0001539)2.90982027
34photoreceptor cell maintenance (GO:0045494)2.90820952
35retinal cone cell development (GO:0046549)2.87158565
36behavioral response to ethanol (GO:0048149)2.86191406
37G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.84516976
38respiratory chain complex IV assembly (GO:0008535)2.84258900
39nonmotile primary cilium assembly (GO:0035058)2.80901370
40phosphatidylinositol acyl-chain remodeling (GO:0036149)2.80707670
41transmission of nerve impulse (GO:0019226)2.78869152
42platelet dense granule organization (GO:0060155)2.78423321
43protein complex biogenesis (GO:0070271)2.78096256
44cilium morphogenesis (GO:0060271)2.76914617
45sulfation (GO:0051923)2.74233843
46regulation of rhodopsin mediated signaling pathway (GO:0022400)2.73808929
47multicellular organism reproduction (GO:0032504)2.73705742
48regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.73606158
49cAMP catabolic process (GO:0006198)2.73522409
50primary amino compound metabolic process (GO:1901160)2.72268695
51auditory receptor cell stereocilium organization (GO:0060088)2.72168559
52neuronal action potential (GO:0019228)2.71890649
53negative regulation of telomere maintenance (GO:0032205)2.71348563
54epithelial cilium movement (GO:0003351)2.71214438
55tachykinin receptor signaling pathway (GO:0007217)2.69762299
56serotonin metabolic process (GO:0042428)2.68233132
57rhodopsin mediated signaling pathway (GO:0016056)2.67921925
58mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.67568998
59mitochondrial respiratory chain complex I assembly (GO:0032981)2.67568998
60NADH dehydrogenase complex assembly (GO:0010257)2.67568998
61positive regulation of defense response to virus by host (GO:0002230)2.67335670
62pyrimidine ribonucleoside catabolic process (GO:0046133)2.63626192
63cytochrome complex assembly (GO:0017004)2.63284635
64negative regulation of cytosolic calcium ion concentration (GO:0051481)2.62583224
65regulation of action potential (GO:0098900)2.61467788
66protein K11-linked deubiquitination (GO:0035871)2.60178778
67detection of mechanical stimulus involved in sensory perception (GO:0050974)2.59795042
68DNA methylation involved in gamete generation (GO:0043046)2.59649514
69regulation of neurotransmitter uptake (GO:0051580)2.58131634
70cilium organization (GO:0044782)2.58051653
71cyclic nucleotide catabolic process (GO:0009214)2.57322359
72oxidative demethylation (GO:0070989)2.56289557
73photoreceptor cell development (GO:0042461)2.55754562
74cornea development in camera-type eye (GO:0061303)2.55669752
75nucleoside transmembrane transport (GO:1901642)2.55429366
76reciprocal DNA recombination (GO:0035825)2.55043051
77reciprocal meiotic recombination (GO:0007131)2.55043051
78mitochondrial respiratory chain complex assembly (GO:0033108)2.54837860
79kidney morphogenesis (GO:0060993)2.54042205
80tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.52728608
81RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.52728608
82synaptic transmission, cholinergic (GO:0007271)2.52508504
83adaptation of signaling pathway (GO:0023058)2.52202211
84negative regulation of mast cell activation (GO:0033004)2.51667189
85cilium assembly (GO:0042384)2.50842391
86positive regulation of fatty acid transport (GO:2000193)2.50634192
87recombinational repair (GO:0000725)2.50023605
88double-strand break repair via homologous recombination (GO:0000724)2.49637267
89replication fork processing (GO:0031297)2.49408438
90negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.49030512
91negative regulation of translation, ncRNA-mediated (GO:0040033)2.49030512
92regulation of translation, ncRNA-mediated (GO:0045974)2.49030512
93preassembly of GPI anchor in ER membrane (GO:0016254)2.47438984
94NAD biosynthetic process (GO:0009435)2.47348397
95RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.46801022
96interferon-gamma production (GO:0032609)2.46573953
97regulation of cilium movement (GO:0003352)2.46353647
98inner ear receptor stereocilium organization (GO:0060122)2.45548789
99regulation of hippo signaling (GO:0035330)2.45183699
100endoderm formation (GO:0001706)2.44995992

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.58999993
2VDR_22108803_ChIP-Seq_LS180_Human3.24351515
3GBX2_23144817_ChIP-Seq_PC3_Human3.16835517
4EZH2_22144423_ChIP-Seq_EOC_Human3.07224409
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.88360556
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.63429051
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.55264318
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.38547243
9IGF1R_20145208_ChIP-Seq_DFB_Human2.37732570
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.30215983
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.19484879
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.12536618
13TAF15_26573619_Chip-Seq_HEK293_Human2.10831043
14P300_19829295_ChIP-Seq_ESCs_Human2.07775229
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.07661363
16CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04348955
17EWS_26573619_Chip-Seq_HEK293_Human2.02853048
18FUS_26573619_Chip-Seq_HEK293_Human1.98208253
19ER_23166858_ChIP-Seq_MCF-7_Human1.87803347
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.78887857
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.76963742
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.75146116
23BCAT_22108803_ChIP-Seq_LS180_Human1.74993041
24EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.68517843
25PCGF2_27294783_Chip-Seq_ESCs_Mouse1.67131712
26UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.66563061
27STAT3_23295773_ChIP-Seq_U87_Human1.64662585
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.63728411
29SMAD4_21799915_ChIP-Seq_A2780_Human1.59522411
30HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.59108754
31PIAS1_25552417_ChIP-Seq_VCAP_Human1.58115373
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57935813
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56551650
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.56349608
35POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.52315206
36TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52315206
37IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52091161
38CBP_20019798_ChIP-Seq_JUKART_Human1.52091161
39TCF4_23295773_ChIP-Seq_U87_Human1.49265795
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.49121410
41TP53_22573176_ChIP-Seq_HFKS_Human1.48070392
42MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44404304
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.42978778
44SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42250506
45NR3C1_21868756_ChIP-Seq_MCF10A_Human1.41151745
46* AR_25329375_ChIP-Seq_VCAP_Human1.40805918
47TCF4_22108803_ChIP-Seq_LS180_Human1.39885799
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.38089360
49REST_21632747_ChIP-Seq_MESCs_Mouse1.37855867
50MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.37440512
51NANOG_19829295_ChIP-Seq_ESCs_Human1.35626933
52SOX2_19829295_ChIP-Seq_ESCs_Human1.35626933
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.35229241
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32447602
55PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32237246
56PRDM14_20953172_ChIP-Seq_ESCs_Human1.31319379
57SUZ12_27294783_Chip-Seq_NPCs_Mouse1.31128263
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.30723908
59IRF1_19129219_ChIP-ChIP_H3396_Human1.28187494
60AR_21572438_ChIP-Seq_LNCaP_Human1.28172008
61FOXA1_27270436_Chip-Seq_PROSTATE_Human1.26645129
62FOXA1_25329375_ChIP-Seq_VCAP_Human1.26645129
63EZH2_27294783_Chip-Seq_NPCs_Mouse1.26229075
64RNF2_27304074_Chip-Seq_NSC_Mouse1.25560167
65EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.24688133
66RUNX2_22187159_ChIP-Seq_PCA_Human1.24171540
67NFE2_27457419_Chip-Seq_LIVER_Mouse1.24091674
68GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21071046
69KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20485235
70SMAD4_21741376_ChIP-Seq_EPCs_Human1.19881868
71FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18579639
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.18206908
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15889038
74CDX2_22108803_ChIP-Seq_LS180_Human1.15744336
75GATA3_21878914_ChIP-Seq_MCF-7_Human1.14828366
76OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12089015
77NCOR_22424771_ChIP-Seq_293T_Human1.11658263
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.11235416
79TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10950972
80CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.10707106
81AR_20517297_ChIP-Seq_VCAP_Human1.09229109
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09039903
83ETV2_25802403_ChIP-Seq_MESCs_Mouse1.08931503
84CRX_20693478_ChIP-Seq_RETINA_Mouse1.07378941
85P53_22387025_ChIP-Seq_ESCs_Mouse1.05375474
86MYC_18940864_ChIP-ChIP_HL60_Human1.04877246
87HOXB7_26014856_ChIP-Seq_BT474_Human1.04122572
88EGR1_23403033_ChIP-Seq_LIVER_Mouse1.02529104
89TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02175827
90DROSHA_22980978_ChIP-Seq_HELA_Human0.98585237
91STAT3_18555785_Chip-Seq_ESCs_Mouse0.98460269
92E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.97911778
93PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96869709
94TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.94829607
95GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.94599699
96AUTS2_25519132_ChIP-Seq_293T-REX_Human0.94388592
97GABP_17652178_ChIP-ChIP_JURKAT_Human0.94228821
98SOX2_21211035_ChIP-Seq_LN229_Gbm0.93532374
99E2F1_18555785_Chip-Seq_ESCs_Mouse0.93502956
100TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.93442190

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003195_calcinosis3.25304695
2MP0008877_abnormal_DNA_methylation2.83418107
3MP0005551_abnormal_eye_electrophysiolog2.66237060
4MP0003646_muscle_fatigue2.64839848
5MP0000569_abnormal_digit_pigmentation2.45848042
6MP0002638_abnormal_pupillary_reflex2.36637338
7MP0006072_abnormal_retinal_apoptosis2.34715374
8MP0001968_abnormal_touch/_nociception2.33349466
9MP0004043_abnormal_pH_regulation2.23208186
10MP0002102_abnormal_ear_morphology2.14440442
11MP0009046_muscle_twitch2.12390456
12MP0001501_abnormal_sleep_pattern2.08123237
13MP0002837_dystrophic_cardiac_calcinosis2.05129184
14MP0002736_abnormal_nociception_after2.00156322
15MP0009745_abnormal_behavioral_response1.99750546
16MP0003136_yellow_coat_color1.95437789
17MP0005253_abnormal_eye_physiology1.91475890
18MP0008872_abnormal_physiological_respon1.91086660
19MP0002876_abnormal_thyroid_physiology1.89260522
20MP0005646_abnormal_pituitary_gland1.87907714
21MP0003787_abnormal_imprinting1.86238687
22MP0001485_abnormal_pinna_reflex1.79923186
23MP0004142_abnormal_muscle_tone1.78843564
24MP0000372_irregular_coat_pigmentation1.77188580
25MP0005645_abnormal_hypothalamus_physiol1.75291930
26MP0005174_abnormal_tail_pigmentation1.71994072
27MP0001986_abnormal_taste_sensitivity1.71888359
28MP0000427_abnormal_hair_cycle1.71555221
29MP0006276_abnormal_autonomic_nervous1.70943855
30MP0003880_abnormal_central_pattern1.64895296
31MP0004147_increased_porphyrin_level1.63619182
32MP0002272_abnormal_nervous_system1.63164317
33MP0004133_heterotaxia1.62352849
34MP0004885_abnormal_endolymph1.55354092
35MP0001486_abnormal_startle_reflex1.54458644
36MP0006292_abnormal_olfactory_placode1.48465195
37MP0010386_abnormal_urinary_bladder1.40240068
38MP0000631_abnormal_neuroendocrine_gland1.39389209
39MP0002163_abnormal_gland_morphology1.37776809
40MP0008875_abnormal_xenobiotic_pharmacok1.36863289
41MP0002572_abnormal_emotion/affect_behav1.33021684
42MP0002653_abnormal_ependyma_morphology1.32055514
43MP0002064_seizures1.27541023
44MP0002557_abnormal_social/conspecific_i1.26176632
45MP0001529_abnormal_vocalization1.25124872
46MP0004742_abnormal_vestibular_system1.24005568
47MP0001970_abnormal_pain_threshold1.23897465
48MP0002733_abnormal_thermal_nociception1.23567697
49MP0005386_behavior/neurological_phenoty1.23503408
50MP0004924_abnormal_behavior1.23503408
51MP0002735_abnormal_chemical_nociception1.23023724
52MP0001984_abnormal_olfaction1.21992747
53MP0002938_white_spotting1.21109971
54MP0002138_abnormal_hepatobiliary_system1.20871532
55MP0005084_abnormal_gallbladder_morpholo1.20727540
56MP0004145_abnormal_muscle_electrophysio1.19484689
57MP0003011_delayed_dark_adaptation1.16829526
58MP0002928_abnormal_bile_duct1.15397234
59MP0003890_abnormal_embryonic-extraembry1.12212332
60MP0005379_endocrine/exocrine_gland_phen1.12202467
61MP0002160_abnormal_reproductive_system1.11318882
62MP0002067_abnormal_sensory_capabilities1.11168669
63MP0005195_abnormal_posterior_eye1.10925482
64MP0005389_reproductive_system_phenotype1.08967362
65MP0000383_abnormal_hair_follicle1.07614771
66MP0003635_abnormal_synaptic_transmissio1.06650561
67MP0000230_abnormal_systemic_arterial1.06323024
68MP0008775_abnormal_heart_ventricle1.03263537
69MP0002095_abnormal_skin_pigmentation1.03161347
70MP0002063_abnormal_learning/memory/cond1.01122313
71MP0005410_abnormal_fertilization1.00918240
72MP0003252_abnormal_bile_duct1.00883463
73MP0005671_abnormal_response_to1.00482385
74MP0005085_abnormal_gallbladder_physiolo0.96170528
75MP0004215_abnormal_myocardial_fiber0.94983896
76MP0005167_abnormal_blood-brain_barrier0.94724413
77MP0002234_abnormal_pharynx_morphology0.94628370
78MP0005377_hearing/vestibular/ear_phenot0.94476361
79MP0003878_abnormal_ear_physiology0.94476361
80MP0002229_neurodegeneration0.93418967
81MP0002734_abnormal_mechanical_nocicepti0.91993291
82MP0001905_abnormal_dopamine_level0.91457903
83MP0002752_abnormal_somatic_nervous0.89857435
84MP0008995_early_reproductive_senescence0.89518031
85MP0002693_abnormal_pancreas_physiology0.88283507
86MP0001963_abnormal_hearing_physiology0.86052842
87MP0003137_abnormal_impulse_conducting0.83005965
88MP0002751_abnormal_autonomic_nervous0.82709255
89MP0003698_abnormal_male_reproductive0.82266580
90MP0005075_abnormal_melanosome_morpholog0.82129626
91MP0000026_abnormal_inner_ear0.81946789
92MP0003718_maternal_effect0.81792462
93MP0000778_abnormal_nervous_system0.80358598
94MP0000538_abnormal_urinary_bladder0.79827331
95MP0003283_abnormal_digestive_organ0.79744912
96MP0001324_abnormal_eye_pigmentation0.77555570
97MP0001919_abnormal_reproductive_system0.77516612
98MP0002184_abnormal_innervation0.76462380
99MP0002210_abnormal_sex_determination0.75308173
100MP0003121_genomic_imprinting0.74484742

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.57454169
2Congenital stationary night blindness (HP:0007642)4.40811015
3Molar tooth sign on MRI (HP:0002419)4.20949188
4Abnormality of midbrain morphology (HP:0002418)4.20949188
5Pancreatic fibrosis (HP:0100732)4.05488001
6True hermaphroditism (HP:0010459)4.00802076
7Nephronophthisis (HP:0000090)3.46583002
8Abnormality of the renal cortex (HP:0011035)3.32814766
9Attenuation of retinal blood vessels (HP:0007843)3.22894719
10Abnormality of the renal medulla (HP:0100957)3.09449433
11Medial flaring of the eyebrow (HP:0010747)3.07552801
12Hyperventilation (HP:0002883)3.01333829
13Abolished electroretinogram (ERG) (HP:0000550)2.93884696
14Type II lissencephaly (HP:0007260)2.89541588
15Chronic hepatic failure (HP:0100626)2.85778969
16Gaze-evoked nystagmus (HP:0000640)2.85210221
17Cystic liver disease (HP:0006706)2.77871722
18Hyperalaninemia (HP:0003348)2.72620204
19Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.72620204
20Abnormality of alanine metabolism (HP:0010916)2.72620204
21Progressive cerebellar ataxia (HP:0002073)2.72614426
22Abnormal rod and cone electroretinograms (HP:0008323)2.67989190
23Renal cortical cysts (HP:0000803)2.67349371
24Genetic anticipation (HP:0003743)2.56287937
25Inability to walk (HP:0002540)2.48123902
26Sclerocornea (HP:0000647)2.43017934
27Aplasia/Hypoplasia of the tibia (HP:0005772)2.42001226
28Tubular atrophy (HP:0000092)2.41564987
29Large for gestational age (HP:0001520)2.41467903
30Methylmalonic acidemia (HP:0002912)2.41268772
31Pendular nystagmus (HP:0012043)2.39425196
32Gait imbalance (HP:0002141)2.38474005
33Bony spicule pigmentary retinopathy (HP:0007737)2.34379149
34Congenital primary aphakia (HP:0007707)2.33507502
35Decreased central vision (HP:0007663)2.33209557
36Increased corneal curvature (HP:0100692)2.30790902
37Keratoconus (HP:0000563)2.30790902
38Progressive inability to walk (HP:0002505)2.30673292
39Congenital sensorineural hearing impairment (HP:0008527)2.29509932
40Congenital, generalized hypertrichosis (HP:0004540)2.28604713
41Polydipsia (HP:0001959)2.28454726
42Abnormal drinking behavior (HP:0030082)2.28454726
43Decreased electroretinogram (ERG) amplitude (HP:0000654)2.28015632
44Clumsiness (HP:0002312)2.25443915
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.21954160
46Dynein arm defect of respiratory motile cilia (HP:0012255)2.18615514
47Absent/shortened dynein arms (HP:0200106)2.18615514
48Broad-based gait (HP:0002136)2.17782624
49Furrowed tongue (HP:0000221)2.16821986
50Abnormal biliary tract physiology (HP:0012439)2.16767762
51Bile duct proliferation (HP:0001408)2.16767762
52Ketoacidosis (HP:0001993)2.15695281
53Decreased circulating renin level (HP:0003351)2.14502757
54Methylmalonic aciduria (HP:0012120)2.14227108
55Chorioretinal atrophy (HP:0000533)2.13409026
56Nephrogenic diabetes insipidus (HP:0009806)2.12175696
57Anencephaly (HP:0002323)2.11151894
58Congenital hepatic fibrosis (HP:0002612)2.09113952
59Absent rod-and cone-mediated responses on ERG (HP:0007688)2.04348623
60Abnormality of macular pigmentation (HP:0008002)2.04116031
61Abnormality of the pons (HP:0007361)2.03515330
62Febrile seizures (HP:0002373)2.01385956
63Male pseudohermaphroditism (HP:0000037)2.01270028
64Genital tract atresia (HP:0001827)2.00691160
65Hypothermia (HP:0002045)1.99784233
66Ketosis (HP:0001946)1.98790071
67Hypoplasia of the pons (HP:0012110)1.98182772
68Protruding tongue (HP:0010808)1.98056391
69Agitation (HP:0000713)1.97930249
70Lissencephaly (HP:0001339)1.96276017
71Polyuria (HP:0000103)1.94633532
723-Methylglutaconic aciduria (HP:0003535)1.94360804
73Fair hair (HP:0002286)1.94048420
74Cerebellar dysplasia (HP:0007033)1.93998607
75Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.93600469
76Vaginal atresia (HP:0000148)1.91911526
77Increased CSF lactate (HP:0002490)1.91501059
78Aplasia/Hypoplasia of the fovea (HP:0008060)1.91230392
79Hypoplasia of the fovea (HP:0007750)1.91230392
80Optic nerve hypoplasia (HP:0000609)1.86863038
81Postaxial foot polydactyly (HP:0001830)1.84618729
82Intestinal atresia (HP:0011100)1.84422312
83Retinitis pigmentosa (HP:0000510)1.82396934
84Hemiparesis (HP:0001269)1.82243065
85Dyskinesia (HP:0100660)1.80471866
86Hyperglycinemia (HP:0002154)1.79030250
87Abnormal ciliary motility (HP:0012262)1.77463470
88Mitochondrial inheritance (HP:0001427)1.75497520
89Patellar aplasia (HP:0006443)1.74850364
90Thyroiditis (HP:0100646)1.74204921
91Stomach cancer (HP:0012126)1.72929986
92Hypoproteinemia (HP:0003075)1.70881490
93Absent speech (HP:0001344)1.70662935
94Abnormal respiratory motile cilium morphology (HP:0005938)1.70459960
95Abnormal respiratory epithelium morphology (HP:0012253)1.70459960
96Tachypnea (HP:0002789)1.70350581
97Constricted visual fields (HP:0001133)1.70108250
98Retinal dysplasia (HP:0007973)1.68215608
99Focal seizures (HP:0007359)1.67281360
100Abnormality of the fovea (HP:0000493)1.66125876

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK7.09698612
2BMPR1B3.48314744
3ADRBK23.32853229
4MAP4K22.73033338
5ACVR1B2.58411458
6WNK32.44411853
7GRK12.38406469
8ZAK2.25599599
9NUAK12.22412589
10TAOK32.19879040
11WNK42.15673071
12INSRR2.07728688
13TXK1.94695938
14PINK11.89264820
15CASK1.80340908
16MAPK131.75529669
17OXSR11.64536208
18STK391.56151900
19TLK11.55150449
20MKNK21.41886165
21MAP3K41.38116423
22MAP2K61.34903026
23TNIK1.32602336
24ADRBK11.31258291
25DAPK21.28304685
26NTRK31.21712027
27PAK31.13075442
28TGFBR11.11755815
29TRIM281.07810129
30PRKCE0.96100162
31PRKCG0.95118330
32MAPKAPK30.91159822
33TEC0.90612386
34PTK2B0.84280576
35PLK20.81337318
36BCKDK0.80735023
37MUSK0.79450296
38PIK3CA0.75106993
39TNK20.74971109
40STK38L0.74903668
41DYRK20.73715031
42PHKG20.72839047
43PHKG10.72839047
44PNCK0.71293647
45VRK10.71186192
46MARK10.70964353
47PIK3CG0.70964056
48CSNK1G10.68128437
49AKT30.67950654
50CAMKK20.67832221
51MAP2K70.67664869
52CSNK1G20.67171460
53ITK0.66676239
54TIE10.66473786
55STK30.66469608
56PKN10.62737092
57TAF10.62079380
58MST40.60658611
59PRKCQ0.60195382
60KIT0.60000301
61CAMK2A0.59766279
62OBSCN0.59511262
63FGFR20.59496492
64NLK0.57475295
65PLK40.57378301
66CSNK1G30.56713102
67IKBKB0.54771572
68CSNK1A1L0.54128622
69NTRK20.53379127
70EIF2AK30.52813571
71MKNK10.51627776
72MAPKAPK50.51281910
73STK160.50675894
74PDK20.49117480
75PRKACA0.49051457
76GRK70.48944335
77SYK0.48156136
78STK110.46543642
79ERBB30.46284652
80BCR0.44296444
81IRAK10.43921465
82GRK50.43524912
83MAPK150.43391157
84TRPM70.42839587
85BRSK20.40609426
86SIK20.39395140
87PRKCA0.38400912
88CSNK1A10.38340539
89CSNK1D0.36893979
90PLK30.36844903
91RPS6KA50.36593352
92PRKAA20.35538668
93EPHA40.34939894
94NEK20.34079471
95CAMK10.33324767
96FLT30.33318633
97PRKG10.32539511
98SGK20.31977234
99FER0.31131652
100LCK0.29940338

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047443.01922987
2Linoleic acid metabolism_Homo sapiens_hsa005912.83951692
3alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.74011251
4Nitrogen metabolism_Homo sapiens_hsa009102.53067707
5Butanoate metabolism_Homo sapiens_hsa006502.43804265
6Nicotine addiction_Homo sapiens_hsa050332.26025678
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.24678865
8Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.12119220
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.08778250
10Maturity onset diabetes of the young_Homo sapiens_hsa049502.07692739
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.00010621
12Ether lipid metabolism_Homo sapiens_hsa005651.94372060
13Tryptophan metabolism_Homo sapiens_hsa003801.93123941
14Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.90727903
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.87714189
16Selenocompound metabolism_Homo sapiens_hsa004501.80138620
17Homologous recombination_Homo sapiens_hsa034401.76322661
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.73791696
19Oxidative phosphorylation_Homo sapiens_hsa001901.64528620
20Morphine addiction_Homo sapiens_hsa050321.52217670
21Caffeine metabolism_Homo sapiens_hsa002321.50314135
22Taste transduction_Homo sapiens_hsa047421.50273127
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.48921192
24Primary bile acid biosynthesis_Homo sapiens_hsa001201.47600342
25Olfactory transduction_Homo sapiens_hsa047401.45554936
26RNA polymerase_Homo sapiens_hsa030201.45472035
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.45151830
28Regulation of autophagy_Homo sapiens_hsa041401.44649863
29Propanoate metabolism_Homo sapiens_hsa006401.44220376
30ABC transporters_Homo sapiens_hsa020101.41797087
31Basal transcription factors_Homo sapiens_hsa030221.39852001
32Protein export_Homo sapiens_hsa030601.39071252
33Fanconi anemia pathway_Homo sapiens_hsa034601.34360636
34Steroid hormone biosynthesis_Homo sapiens_hsa001401.23259493
35GABAergic synapse_Homo sapiens_hsa047271.19101108
36Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.18905922
37Parkinsons disease_Homo sapiens_hsa050121.17490877
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.17176914
39Chemical carcinogenesis_Homo sapiens_hsa052041.16038599
40Serotonergic synapse_Homo sapiens_hsa047261.15438362
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.15290332
42Arachidonic acid metabolism_Homo sapiens_hsa005901.13837119
43Insulin secretion_Homo sapiens_hsa049111.11980321
44Peroxisome_Homo sapiens_hsa041461.10760976
45Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.10727101
46RNA degradation_Homo sapiens_hsa030181.10273973
47Sulfur metabolism_Homo sapiens_hsa009201.08263925
48Retinol metabolism_Homo sapiens_hsa008301.07487426
49Circadian entrainment_Homo sapiens_hsa047131.06591859
50Glutamatergic synapse_Homo sapiens_hsa047241.04162153
51Intestinal immune network for IgA production_Homo sapiens_hsa046721.03963740
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.98197911
53One carbon pool by folate_Homo sapiens_hsa006700.90733783
54Primary immunodeficiency_Homo sapiens_hsa053400.85599012
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.84398160
56Salivary secretion_Homo sapiens_hsa049700.83810412
57Calcium signaling pathway_Homo sapiens_hsa040200.82151209
58Glycerolipid metabolism_Homo sapiens_hsa005610.81715614
59Huntingtons disease_Homo sapiens_hsa050160.81230347
60Cardiac muscle contraction_Homo sapiens_hsa042600.81121967
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.80814581
62Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.79872922
63Type I diabetes mellitus_Homo sapiens_hsa049400.78088881
64Ovarian steroidogenesis_Homo sapiens_hsa049130.77564498
65Graft-versus-host disease_Homo sapiens_hsa053320.77282321
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77162966
67Collecting duct acid secretion_Homo sapiens_hsa049660.75441323
68Alzheimers disease_Homo sapiens_hsa050100.75150700
69beta-Alanine metabolism_Homo sapiens_hsa004100.68472487
70Purine metabolism_Homo sapiens_hsa002300.64525387
71Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.61634163
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.60928275
73Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60435518
74Histidine metabolism_Homo sapiens_hsa003400.60095815
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57920003
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.57847227
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.57474014
78Asthma_Homo sapiens_hsa053100.57391354
79Dopaminergic synapse_Homo sapiens_hsa047280.55566673
80Fat digestion and absorption_Homo sapiens_hsa049750.54555092
81Long-term depression_Homo sapiens_hsa047300.54470997
82Non-homologous end-joining_Homo sapiens_hsa034500.53782746
83Metabolic pathways_Homo sapiens_hsa011000.53438023
84Dorso-ventral axis formation_Homo sapiens_hsa043200.53359312
85Autoimmune thyroid disease_Homo sapiens_hsa053200.53279457
86Allograft rejection_Homo sapiens_hsa053300.51116949
87Cocaine addiction_Homo sapiens_hsa050300.43333909
88Cholinergic synapse_Homo sapiens_hsa047250.39816168
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.39732940
90Circadian rhythm_Homo sapiens_hsa047100.39676614
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.39124991
92cAMP signaling pathway_Homo sapiens_hsa040240.38861621
93Mineral absorption_Homo sapiens_hsa049780.37583886
94Renin secretion_Homo sapiens_hsa049240.37521276
95Amphetamine addiction_Homo sapiens_hsa050310.36693332
96Fatty acid degradation_Homo sapiens_hsa000710.36166049
97Sphingolipid metabolism_Homo sapiens_hsa006000.33535339
98Vitamin digestion and absorption_Homo sapiens_hsa049770.32855008
99Oxytocin signaling pathway_Homo sapiens_hsa049210.31382929
100Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.30599851

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »