KIFC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.59224068
2DNA unwinding involved in DNA replication (GO:0006268)4.96599782
3* mitotic sister chromatid segregation (GO:0000070)4.81128034
4DNA topological change (GO:0006265)4.78396797
5protein localization to chromosome, centromeric region (GO:0071459)4.75582237
6nuclear pore organization (GO:0006999)4.71430707
7nuclear pore complex assembly (GO:0051292)4.60823867
8* sister chromatid segregation (GO:0000819)4.54135983
9regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.49715489
10regulation of gene silencing by RNA (GO:0060966)4.37110018
11regulation of posttranscriptional gene silencing (GO:0060147)4.37110018
12regulation of gene silencing by miRNA (GO:0060964)4.37110018
13establishment of integrated proviral latency (GO:0075713)4.30831255
14mitotic nuclear envelope disassembly (GO:0007077)4.24938268
15mitotic metaphase plate congression (GO:0007080)4.16580001
16mitotic chromosome condensation (GO:0007076)4.16175153
17DNA replication-dependent nucleosome organization (GO:0034723)4.11014189
18DNA replication-dependent nucleosome assembly (GO:0006335)4.11014189
19folic acid-containing compound biosynthetic process (GO:0009396)4.08085804
20heterochromatin organization (GO:0070828)4.06185067
21DNA packaging (GO:0006323)4.06128207
22DNA replication initiation (GO:0006270)4.02898973
23membrane disassembly (GO:0030397)3.97187417
24nuclear envelope disassembly (GO:0051081)3.97187417
25positive regulation of chromosome segregation (GO:0051984)3.95473014
26pre-miRNA processing (GO:0031054)3.86517626
27regulation of spindle organization (GO:0090224)3.79034409
28DNA duplex unwinding (GO:0032508)3.72569120
29regulation of translational fidelity (GO:0006450)3.72120189
30DNA geometric change (GO:0032392)3.72058420
31DNA strand elongation involved in DNA replication (GO:0006271)3.71513326
32regulation of sister chromatid cohesion (GO:0007063)3.64167781
33positive regulation of mitotic sister chromatid separation (GO:1901970)3.62862788
34positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.62862788
35positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.62862788
36metaphase plate congression (GO:0051310)3.60497661
37negative regulation of histone methylation (GO:0031061)3.58123719
38chromatin assembly (GO:0031497)3.56625475
39regulation of mitotic spindle organization (GO:0060236)3.55788989
40regulation of histone H3-K9 methylation (GO:0051570)3.54815672
41kinetochore organization (GO:0051383)3.52426196
42DNA strand elongation (GO:0022616)3.52140337
43pore complex assembly (GO:0046931)3.46492595
44protein localization to chromosome (GO:0034502)3.45474669
45regulation of telomere maintenance via telomerase (GO:0032210)3.45091982
46dosage compensation (GO:0007549)3.44094840
47paraxial mesoderm development (GO:0048339)3.43714304
48DNA ligation (GO:0006266)3.41223985
49negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.39261391
50nucleosome disassembly (GO:0006337)3.37686340
51protein-DNA complex disassembly (GO:0032986)3.37686340
52IMP biosynthetic process (GO:0006188)3.37211642
53formation of translation preinitiation complex (GO:0001731)3.35978879
54protein complex localization (GO:0031503)3.35627102
55DNA replication checkpoint (GO:0000076)3.35166750
56regulation of RNA export from nucleus (GO:0046831)3.34868749
57regulation of chromosome segregation (GO:0051983)3.34079878
58protein K6-linked ubiquitination (GO:0085020)3.32916300
59establishment of chromosome localization (GO:0051303)3.31666424
60establishment of viral latency (GO:0019043)3.29535145
61telomere maintenance via semi-conservative replication (GO:0032201)3.22952788
62attachment of spindle microtubules to kinetochore (GO:0008608)3.22635865
63spliceosomal tri-snRNP complex assembly (GO:0000244)3.22157327
64COPI coating of Golgi vesicle (GO:0048205)3.21640589
65Golgi transport vesicle coating (GO:0048200)3.21640589
66proline biosynthetic process (GO:0006561)3.21568104
67somatic hypermutation of immunoglobulin genes (GO:0016446)3.20834196
68somatic diversification of immune receptors via somatic mutation (GO:0002566)3.20834196
69regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.20460166
70nuclear envelope organization (GO:0006998)3.17498440
71establishment of apical/basal cell polarity (GO:0035089)3.17289105
72positive regulation of DNA-dependent DNA replication (GO:2000105)3.16968952
73regulation of centrosome cycle (GO:0046605)3.16009307
74chromatin assembly or disassembly (GO:0006333)3.14283184
75meiotic chromosome segregation (GO:0045132)3.14196559
76DNA synthesis involved in DNA repair (GO:0000731)3.14184401
77regulation of mammary gland epithelial cell proliferation (GO:0033599)3.13669217
78negative regulation of chromosome segregation (GO:0051985)3.09812948
79DNA conformation change (GO:0071103)3.06950573
80mitotic sister chromatid cohesion (GO:0007064)3.06327131
81positive regulation of SMAD protein import into nucleus (GO:0060391)3.05857340
82kinetochore assembly (GO:0051382)3.05742115
83negative regulation of mRNA processing (GO:0050686)3.05722820
84histone H2A monoubiquitination (GO:0035518)3.05053186
85peptidyl-arginine omega-N-methylation (GO:0035247)3.02867325
86nucleobase biosynthetic process (GO:0046112)3.02631914
87* chromosome segregation (GO:0007059)3.01573025
88ATP-dependent chromatin remodeling (GO:0043044)3.01509635
89negative regulation of mRNA metabolic process (GO:1903312)3.01366621
90chromosome condensation (GO:0030261)3.00322110
91spindle checkpoint (GO:0031577)3.00243495
92nucleotide-excision repair, DNA gap filling (GO:0006297)2.99860893
93mitotic recombination (GO:0006312)2.99036859
94regulation of translational termination (GO:0006449)2.98733613
95negative regulation of RNA splicing (GO:0033119)2.96797883
96mRNA stabilization (GO:0048255)2.95784871
97RNA stabilization (GO:0043489)2.95784871
98cellular protein complex localization (GO:0034629)2.95356649
99regulation of centriole replication (GO:0046599)2.93732799
100regulation of hippo signaling (GO:0035330)2.93598914
101spindle assembly checkpoint (GO:0071173)2.93372632
102regulation of mitotic metaphase/anaphase transition (GO:0030071)2.92995916
103IMP metabolic process (GO:0046040)2.92730012
104establishment of mitotic spindle localization (GO:0040001)2.90432363
105regulation of gene silencing (GO:0060968)2.90169000
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.89896498
107negative regulation of sister chromatid segregation (GO:0033046)2.89896498
108negative regulation of mitotic sister chromatid separation (GO:2000816)2.89896498
109negative regulation of mitotic sister chromatid segregation (GO:0033048)2.89896498
110telomere maintenance via recombination (GO:0000722)2.88979335
111regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.87830748
112V(D)J recombination (GO:0033151)2.87761249
113regulation of helicase activity (GO:0051095)2.87696630
114regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.87489309
115mitotic spindle checkpoint (GO:0071174)2.86582569
116mitotic cytokinesis (GO:0000281)2.86521904
117mitotic spindle assembly checkpoint (GO:0007094)2.86461558
118telomere maintenance via telomere lengthening (GO:0010833)2.85942617
119double-strand break repair via nonhomologous end joining (GO:0006303)2.85348686
120non-recombinational repair (GO:0000726)2.85348686
121protein export from nucleus (GO:0006611)2.85281716
122regulation of sister chromatid segregation (GO:0033045)2.85281528
123regulation of mitotic sister chromatid separation (GO:0010965)2.85281528
124regulation of mitotic sister chromatid segregation (GO:0033047)2.85281528
125microtubule depolymerization (GO:0007019)2.85065111
126chromatin remodeling at centromere (GO:0031055)2.84051486
127DNA replication-independent nucleosome assembly (GO:0006336)2.83730995
128DNA replication-independent nucleosome organization (GO:0034724)2.83730995
129CENP-A containing nucleosome assembly (GO:0034080)2.82610146
130nucleobase-containing small molecule interconversion (GO:0015949)2.80191503
131glucocorticoid receptor signaling pathway (GO:0042921)2.78252064
132regulation of nucleobase-containing compound transport (GO:0032239)2.77767964
133mitotic cell cycle (GO:0000278)2.77420894
134negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.77153403

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.20503748
2* FOXM1_23109430_ChIP-Seq_U2OS_Human5.91742958
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.73128694
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.47130950
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.45663621
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.98609019
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.84078541
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.81194436
9MYC_22102868_ChIP-Seq_BL_Human2.40885454
10SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.38706805
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.33170004
12KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.23711636
13KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.23711636
14KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.23711636
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.21208014
16AR_21909140_ChIP-Seq_LNCAP_Human2.09622394
17KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.07011219
18* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.05771534
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.01839014
20NANOG_18555785_ChIP-Seq_MESCs_Mouse2.00115317
21POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.99816899
22E2F1_21310950_ChIP-Seq_MCF-7_Human1.98030105
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92407150
24XRN2_22483619_ChIP-Seq_HELA_Human1.89867550
25POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.74162313
26MYCN_18555785_ChIP-Seq_MESCs_Mouse1.68474003
27STAT3_1855785_ChIP-Seq_MESCs_Mouse1.65209226
28ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.64221847
29NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.60955367
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.56569875
31EST1_17652178_ChIP-ChIP_JURKAT_Human1.56413811
32ETS1_20019798_ChIP-Seq_JURKAT_Human1.55503188
33TP63_19390658_ChIP-ChIP_HaCaT_Human1.54283225
34NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.54182328
35VDR_21846776_ChIP-Seq_THP-1_Human1.51338784
36* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.51017962
37SOX2_18555785_ChIP-Seq_MESCs_Mouse1.50982123
38CREB1_15753290_ChIP-ChIP_HEK293T_Human1.48666096
39CIITA_25753668_ChIP-Seq_RAJI_Human1.47418851
40* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.45819448
41SALL1_21062744_ChIP-ChIP_HESCs_Human1.43356176
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.42141370
43NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.40077667
44ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.39563562
45KLF4_18555785_ChIP-Seq_MESCs_Mouse1.38797422
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.38647954
47KDM5A_27292631_Chip-Seq_BREAST_Human1.38575235
48POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.36362609
49TTF2_22483619_ChIP-Seq_HELA_Human1.36153643
50CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32870973
51SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.32649031
52* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.31973610
53ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29284664
54SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.28816888
55DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.27380542
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27286020
57NANOG_21062744_ChIP-ChIP_HESCs_Human1.26974308
58SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.24381286
59FOXP3_21729870_ChIP-Seq_TREG_Human1.24144475
60PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.23544571
61CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.22415801
62DCP1A_22483619_ChIP-Seq_HELA_Human1.21549116
63* VDR_23849224_ChIP-Seq_CD4+_Human1.20308910
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20284377
65* GABP_19822575_ChIP-Seq_HepG2_Human1.19420753
66JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.18964449
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.18639718
68CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.18620354
69KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.18272894
70HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.17321251
71KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.14552990
72TFEB_21752829_ChIP-Seq_HELA_Human1.14082066
73YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13498554
74KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.12122340
75TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12079158
76NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.11574782
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10850283
78ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.09861955
79RACK7_27058665_Chip-Seq_MCF-7_Human1.07428451
80POU5F1_16518401_ChIP-PET_MESCs_Mouse1.06572334
81TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.06389649
82* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.05906082
83TP63_17297297_ChIP-ChIP_HaCaT_Human1.05533014
84CLOCK_20551151_ChIP-Seq_293T_Human1.04680045
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.04506809
86NCOR1_26117541_ChIP-Seq_K562_Human1.04155389
87* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.00713190
88GABP_17652178_ChIP-ChIP_JURKAT_Human1.00427702
89* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.99943863
90E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99549344
91LXR_22292898_ChIP-Seq_THP-1_Human0.99087628
92* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.98595339
93TCF7_22412390_ChIP-Seq_EML_Mouse0.97976775
94CHD1_26751641_Chip-Seq_LNCaP_Human0.97566752
95* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.96422664
96MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.96386648
97* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.96244698
98TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96180366
99NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.95431001
100* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.94832749
101* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.93714253
102DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.93345044
103* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93312417
104KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93239044
105YY1_21170310_ChIP-Seq_MESCs_Mouse0.93072713
106ELK3_25401928_ChIP-Seq_HUVEC_Human0.92872614
107P300_27058665_Chip-Seq_ZR-75-30cells_Human0.92148249
108HOXB4_20404135_ChIP-ChIP_EML_Mouse0.91289244
109* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.89224995
110* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88631967
111ELF1_17652178_ChIP-ChIP_JURKAT_Human0.88527952
112* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.88253143
113ZFP281_27345836_Chip-Seq_ESCs_Mouse0.87919306
114KDM2B_26808549_Chip-Seq_DND41_Human0.86928162
115ZNF263_19887448_ChIP-Seq_K562_Human0.86887220
116ZFP281_18757296_ChIP-ChIP_E14_Mouse0.86725207
117KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.86405345
118ATF3_27146783_Chip-Seq_COLON_Human0.84391501
119KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.84268157
120SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.84211575
121PKCTHETA_26484144_Chip-Seq_BREAST_Human0.82949965
122SOX17_20123909_ChIP-Seq_XEN_Mouse0.82483477
123RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.81419902
124PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.80490085
125SRY_22984422_ChIP-ChIP_TESTIS_Rat0.80035956

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology4.29473714
2MP0003693_abnormal_embryo_hatching4.06382561
3MP0010094_abnormal_chromosome_stability3.94455513
4MP0004957_abnormal_blastocyst_morpholog3.80753876
5MP0003077_abnormal_cell_cycle3.54528154
6MP0008057_abnormal_DNA_replication3.37163861
7MP0010352_gastrointestinal_tract_polyps2.88716803
8MP0003705_abnormal_hypodermis_morpholog2.66567205
9MP0010307_abnormal_tumor_latency2.51287338
10MP0001730_embryonic_growth_arrest2.49869127
11MP0005076_abnormal_cell_differentiation2.40782772
12MP0000350_abnormal_cell_proliferation2.39051222
13MP0008007_abnormal_cellular_replicative2.17220151
14MP0008932_abnormal_embryonic_tissue2.16363246
15MP0005380_embryogenesis_phenotype2.09194308
16MP0001672_abnormal_embryogenesis/_devel2.09194308
17MP0008058_abnormal_DNA_repair2.07885713
18MP0003123_paternal_imprinting2.06783650
19MP0002084_abnormal_developmental_patter2.02743350
20MP0002085_abnormal_embryonic_tissue1.99362757
21MP0004197_abnormal_fetal_growth/weight/1.98741090
22MP0010030_abnormal_orbit_morphology1.94829662
23MP0001697_abnormal_embryo_size1.91944205
24MP0002086_abnormal_extraembryonic_tissu1.86650558
25MP0003984_embryonic_growth_retardation1.84569356
26MP0002088_abnormal_embryonic_growth/wei1.81656723
27MP0002653_abnormal_ependyma_morphology1.73436284
28MP0002080_prenatal_lethality1.71478417
29MP0009278_abnormal_bone_marrow1.59223629
30MP0003121_genomic_imprinting1.58247313
31MP0003890_abnormal_embryonic-extraembry1.57825707
32MP0000490_abnormal_crypts_of1.53992245
33MP0005451_abnormal_body_composition1.52448038
34MP0003566_abnormal_cell_adhesion1.50433882
35MP0002396_abnormal_hematopoietic_system1.43927722
36MP0003119_abnormal_digestive_system1.43815722
37MP0001293_anophthalmia1.38072193
38MP0001849_ear_inflammation1.37401201
39MP0003567_abnormal_fetal_cardiomyocyte1.35721980
40MP0003786_premature_aging1.34895186
41MP0000313_abnormal_cell_death1.34174816
42MP0000537_abnormal_urethra_morphology1.33266686
43MP0005257_abnormal_intraocular_pressure1.31335186
44MP0003941_abnormal_skin_development1.31066582
45MP0002019_abnormal_tumor_incidence1.30005892
46MP0004264_abnormal_extraembryonic_tissu1.29818663
47MP0001346_abnormal_lacrimal_gland1.28648029
48MP0004808_abnormal_hematopoietic_stem1.28098778
49MP0009697_abnormal_copulation1.27486984
50MP0004133_heterotaxia1.24461938
51MP0009053_abnormal_anal_canal1.23791507
52MP0008877_abnormal_DNA_methylation1.20236703
53MP0003283_abnormal_digestive_organ1.18613270
54MP0000733_abnormal_muscle_development1.15537786
55MP0001915_intracranial_hemorrhage1.13666228
56MP0002009_preneoplasia1.13565980
57MP0002111_abnormal_tail_morphology1.12642211
58MP0005023_abnormal_wound_healing1.12591690
59MP0002697_abnormal_eye_size1.09758798
60MP0003937_abnormal_limbs/digits/tail_de1.08716580
61MP0001348_abnormal_lacrimal_gland1.08354995
62MP0010234_abnormal_vibrissa_follicle1.08146753
63MP0002092_abnormal_eye_morphology1.07188380
64MP0002877_abnormal_melanocyte_morpholog1.06406140
65MP0000428_abnormal_craniofacial_morphol1.06243969
66MP0001661_extended_life_span1.04362575
67MP0003718_maternal_effect1.03832322
68MP0003385_abnormal_body_wall1.01699757
69MP0005623_abnormal_meninges_morphology1.01694897
70MP0001545_abnormal_hematopoietic_system0.99989269
71MP0005397_hematopoietic_system_phenotyp0.99989269
72MP0000566_synostosis0.98502896
73MP0000003_abnormal_adipose_tissue0.96061938
74MP0002089_abnormal_postnatal_growth/wei0.96007123
75MP0000703_abnormal_thymus_morphology0.95875940
76MP0003942_abnormal_urinary_system0.92093229
77MP0000432_abnormal_head_morphology0.91965519
78MP0002925_abnormal_cardiovascular_devel0.91386064
79MP0009703_decreased_birth_body0.90984154
80MP0002210_abnormal_sex_determination0.88719342
81MP0009672_abnormal_birth_weight0.87339980
82MP0005621_abnormal_cell_physiology0.86923014
83MP0003935_abnormal_craniofacial_develop0.85154168
84MP0003950_abnormal_plasma_membrane0.84948687
85MP0008438_abnormal_cutaneous_collagen0.84270478
86MP0008770_decreased_survivor_rate0.84198872
87MP0001145_abnormal_male_reproductive0.84179043
88MP0000858_altered_metastatic_potential0.84010335
89MP0003115_abnormal_respiratory_system0.83832506
90MP0003861_abnormal_nervous_system0.83474399
91MP0002796_impaired_skin_barrier0.81199053
92MP0005384_cellular_phenotype0.81052425
93MP0001286_abnormal_eye_development0.80209666
94MP0002060_abnormal_skin_morphology0.79304438
95MP0000678_abnormal_parathyroid_gland0.78102745
96MP0002932_abnormal_joint_morphology0.76411413
97MP0009333_abnormal_splenocyte_physiolog0.75316753
98MP0000477_abnormal_intestine_morphology0.74595850
99MP0005501_abnormal_skin_physiology0.73578766
100MP0004185_abnormal_adipocyte_glucose0.73410159
101MP0002722_abnormal_immune_system0.73312156
102MP0003453_abnormal_keratinocyte_physiol0.72752238
103MP0003755_abnormal_palate_morphology0.70709614
104MP0003221_abnormal_cardiomyocyte_apopto0.70598195
105MP0004272_abnormal_basement_membrane0.70350319
106MP0003091_abnormal_cell_migration0.69617297
107MP0001727_abnormal_embryo_implantation0.69401986
108MP0000534_abnormal_ureter_morphology0.69054693
109MP0002114_abnormal_axial_skeleton0.68761567
110MP0003448_altered_tumor_morphology0.68282573
111MP0002398_abnormal_bone_marrow0.68277460
112MP0000762_abnormal_tongue_morphology0.67159407
113MP0003806_abnormal_nucleotide_metabolis0.66792109
114MP0001929_abnormal_gametogenesis0.66465472
115MP0005666_abnormal_adipose_tissue0.65372844
116MP0000653_abnormal_sex_gland0.65310988
117MP0004233_abnormal_muscle_weight0.65220725
118MP0003943_abnormal_hepatobiliary_system0.64931114
119MP0002249_abnormal_larynx_morphology0.63884585
120MP0006292_abnormal_olfactory_placode0.63837541
121MP0000689_abnormal_spleen_morphology0.63465881
122MP0010630_abnormal_cardiac_muscle0.62557369
123MP0000266_abnormal_heart_morphology0.61848737
124MP0004858_abnormal_nervous_system0.61419038
125MP0003315_abnormal_perineum_morphology0.60254270
126MP0000358_abnormal_cell_content/0.59269234

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.33146269
2Selective tooth agenesis (HP:0001592)3.39402880
3Astrocytoma (HP:0009592)3.34545759
4Abnormality of the astrocytes (HP:0100707)3.34545759
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.22039498
6Chromsome breakage (HP:0040012)3.18731248
7Abnormality of the labia minora (HP:0012880)3.13229614
8Medulloblastoma (HP:0002885)3.10933262
9Rib fusion (HP:0000902)2.97611996
10Insomnia (HP:0100785)2.91339135
11Rhabdomyosarcoma (HP:0002859)2.85053691
12Neoplasm of the oral cavity (HP:0100649)2.79229815
13Patellar aplasia (HP:0006443)2.78571849
14Cortical dysplasia (HP:0002539)2.75031727
15Absent radius (HP:0003974)2.74799857
16Deviation of the thumb (HP:0009603)2.70301728
17Basal cell carcinoma (HP:0002671)2.68483278
18Increased nuchal translucency (HP:0010880)2.65688164
19Proximal placement of thumb (HP:0009623)2.65400760
20Glioma (HP:0009733)2.60151974
21Aplasia/Hypoplasia of the patella (HP:0006498)2.59965378
22Neoplasm of striated muscle (HP:0009728)2.58271864
23Missing ribs (HP:0000921)2.56733397
24Absent forearm bone (HP:0003953)2.56635412
25Aplasia involving forearm bones (HP:0009822)2.56635412
26Overlapping toe (HP:0001845)2.54660003
27Aplasia/hypoplasia of the humerus (HP:0006507)2.53532193
28Impulsivity (HP:0100710)2.51059933
29Birth length less than 3rd percentile (HP:0003561)2.50847555
30Agnosia (HP:0010524)2.48789022
31Pseudobulbar signs (HP:0002200)2.46225403
32Abnormal gallbladder physiology (HP:0012438)2.46140664
33Cholecystitis (HP:0001082)2.46140664
34Breast hypoplasia (HP:0003187)2.44859244
35Short humerus (HP:0005792)2.44227667
36Reticulocytopenia (HP:0001896)2.42618500
37Meckel diverticulum (HP:0002245)2.42056547
38Abnormal number of incisors (HP:0011064)2.41204538
39Abnormality of the ileum (HP:0001549)2.38358628
40Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.36866735
41Short 4th metacarpal (HP:0010044)2.36866735
42Colon cancer (HP:0003003)2.34327344
43Abnormality of chromosome stability (HP:0003220)2.31945125
44Ulnar bowing (HP:0003031)2.31069494
45Supernumerary spleens (HP:0009799)2.30506296
46Aplasia/Hypoplasia of the uvula (HP:0010293)2.29717444
47Premature rupture of membranes (HP:0001788)2.28375521
48Facial hemangioma (HP:0000329)2.27847775
49Orthostatic hypotension (HP:0001278)2.26895196
50Aplasia/Hypoplasia of the sacrum (HP:0008517)2.23748443
51Progressive muscle weakness (HP:0003323)2.23438750
52Volvulus (HP:0002580)2.22784797
53Broad distal phalanx of finger (HP:0009836)2.21724509
54Long palpebral fissure (HP:0000637)2.20979453
55Abnormality of abdominal situs (HP:0011620)2.20824954
56Abdominal situs inversus (HP:0003363)2.20824954
57Abnormality of reticulocytes (HP:0004312)2.20406591
58Overriding aorta (HP:0002623)2.18067370
59Asymmetry of the thorax (HP:0001555)2.17286408
60Absent thumb (HP:0009777)2.16863915
61Cafe-au-lait spot (HP:0000957)2.16177549
62Nephroblastoma (Wilms tumor) (HP:0002667)2.15415124
63Cerebral aneurysm (HP:0004944)2.13719514
64Squamous cell carcinoma (HP:0002860)2.13527687
65Small intestinal stenosis (HP:0012848)2.12875023
66Duodenal stenosis (HP:0100867)2.12875023
67Hypoplasia of the capital femoral epiphysis (HP:0003090)2.12308479
68Renal duplication (HP:0000075)2.11097811
69Gastrointestinal carcinoma (HP:0002672)2.10890702
70Malignant gastrointestinal tract tumors (HP:0006749)2.10890702
71Esophageal atresia (HP:0002032)2.10858225
72High pitched voice (HP:0001620)2.10310807
73Atresia of the external auditory canal (HP:0000413)2.08714620
74Ankyloglossia (HP:0010296)2.07467303
75Disproportionate tall stature (HP:0001519)2.06899875
76Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.06121258
77Absent epiphyses (HP:0010577)2.06121258
78Myelodysplasia (HP:0002863)2.05955633
79Ectopic kidney (HP:0000086)2.02995653
80Heterotopia (HP:0002282)2.02708464
81Reticulocytosis (HP:0001923)2.02323423
82Prominent nose (HP:0000448)2.01415908
83Deep philtrum (HP:0002002)2.01393313
84Tracheoesophageal fistula (HP:0002575)1.99859947
85Abnormality of the preputium (HP:0100587)1.98986652
86Carpal bone hypoplasia (HP:0001498)1.98653615
87Hyperacusis (HP:0010780)1.98487151
88Duplication of thumb phalanx (HP:0009942)1.98255059
89Embryonal renal neoplasm (HP:0011794)1.98125591
90Supernumerary ribs (HP:0005815)1.97437628
91Neoplasm of the pancreas (HP:0002894)1.97180298
92Elfin facies (HP:0004428)1.96640845
93Skull defect (HP:0001362)1.93515052
94Degeneration of anterior horn cells (HP:0002398)1.93459819
95Abnormality of the anterior horn cell (HP:0006802)1.93459819
96Achilles tendon contracture (HP:0001771)1.92430342
97Small epiphyses (HP:0010585)1.92072030
98Poikiloderma (HP:0001029)1.91610377
99Pointed chin (HP:0000307)1.87424818
10011 pairs of ribs (HP:0000878)1.86850128
101Flared metaphyses (HP:0003015)1.86208906
102Abnormality of the carotid arteries (HP:0005344)1.85945051
103Skin tags (HP:0010609)1.85137992
104Abnormality of the duodenum (HP:0002246)1.85006362
105Deep palmar crease (HP:0006191)1.84999970
106Aplasia/Hypoplasia of the sternum (HP:0006714)1.84916761
107Trismus (HP:0000211)1.84837873
108Shallow orbits (HP:0000586)1.84753976
109Supernumerary bones of the axial skeleton (HP:0009144)1.84223964
110Vertebral fusion (HP:0002948)1.83794167
111Abnormality of oral frenula (HP:0000190)1.83734506
112Long eyelashes (HP:0000527)1.82663655
113Sloping forehead (HP:0000340)1.82511827
114Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.81713017
115Trigonocephaly (HP:0000243)1.81327578
116Abnormality of cochlea (HP:0000375)1.81024185
117Abnormality of the calcaneus (HP:0008364)1.80857202
118Progressive external ophthalmoplegia (HP:0000590)1.80384228
119Short thumb (HP:0009778)1.80289474
120Abnormality of chromosome segregation (HP:0002916)1.78747650
121Entropion (HP:0000621)1.78586429
122Preauricular skin tag (HP:0000384)1.78551243
123Patellar dislocation (HP:0002999)1.77304344
124Biliary tract neoplasm (HP:0100574)1.76106385
125Hypopigmentation of the fundus (HP:0007894)1.75970458
126Broad thumb (HP:0011304)1.75770411
127Termporal pattern (HP:0011008)1.75768534
128Insidious onset (HP:0003587)1.75768534
129High anterior hairline (HP:0009890)1.75605579
130Amaurosis fugax (HP:0100576)1.75175120
131Flattened epiphyses (HP:0003071)1.74014695
132Distal lower limb amyotrophy (HP:0008944)1.73867314
133Urethral obstruction (HP:0000796)1.73837206
134Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.73357262
135Uterine leiomyosarcoma (HP:0002891)1.72720972
136Leiomyosarcoma (HP:0100243)1.72720972
137Ankle contracture (HP:0006466)1.72465722
138Abnormality of the umbilical cord (HP:0010881)1.72139396
139Multiple enchondromatosis (HP:0005701)1.71736215
140Spastic diplegia (HP:0001264)1.71585053
141Microvesicular hepatic steatosis (HP:0001414)1.71423615
142Hemivertebrae (HP:0002937)1.71000460
143Sandal gap (HP:0001852)1.70114637
144Abnormality of the 4th metacarpal (HP:0010012)1.69866120
145Shawl scrotum (HP:0000049)1.69736150
146Abnormal lung lobation (HP:0002101)1.69193117
147Fused cervical vertebrae (HP:0002949)1.69137625
148Horseshoe kidney (HP:0000085)1.68920700
149Broad palm (HP:0001169)1.68664909
150Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.68299285
151Short 1st metacarpal (HP:0010034)1.68299285
152Angiofibromas (HP:0010615)1.67614332
153Broad face (HP:0000283)1.66554060
154Choanal atresia (HP:0000453)1.64771271
155Abnormality of the distal phalanx of the thumb (HP:0009617)1.64437990
156Abnormality of the Achilles tendon (HP:0005109)1.63762284
157Limited elbow extension (HP:0001377)1.63616942
158Abnormal foot bone ossification (HP:0010675)1.63452031
159Thin ribs (HP:0000883)1.62166171
160Renovascular hypertension (HP:0100817)1.61811647

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.44839653
2CDC73.89845934
3SMG13.51534290
4EEF2K3.50858489
5BUB13.46121641
6NEK23.39225926
7WEE12.90493427
8TTK2.70402317
9MAP3K102.66992207
10EPHA22.63057093
11NEK12.37450168
12RPS6KB22.28635701
13PKN21.99614473
14STK101.93686023
15CDK71.87865778
16PLK11.82895568
17CDK41.82233859
18VRK21.74218624
19PBK1.70953949
20CHEK21.60701978
21PASK1.59868053
22IRAK31.56626686
23ICK1.55636069
24TRIB31.55626286
25MAP3K81.54245053
26BRD41.51195681
27AURKB1.50868718
28TSSK61.46859155
29ATR1.44590813
30PAK41.42932729
31ALK1.39408004
32TESK21.38288347
33* CHEK11.36435929
34SRPK11.33889464
35CDK61.31573200
36PRPF4B1.30980214
37STK41.29545768
38CDK81.27248315
39MKNK11.23389735
40AURKA1.17678034
41BRAF1.15006525
42SIK11.14513369
43MTOR1.13885619
44MST1R1.12523561
45LATS21.10465963
46TAF11.08554634
47PIM11.07705722
48PLK31.05048015
49GRK61.04894128
50STK31.01472500
51FGFR41.01031763
52TTN1.00907576
53SCYL21.00730654
54BMX1.00422559
55LATS10.99654393
56CDK20.99584753
57ATM0.98659055
58MKNK20.90292413
59DYRK30.89828198
60BRSK20.88906044
61PDGFRA0.88602763
62LRRK20.82638348
63PLK40.82433071
64EIF2AK10.82059066
65MELK0.79587195
66TYRO30.78154999
67RPS6KA40.77375495
68TLK10.74435057
69CDK10.73396219
70MAPKAPK30.72633008
71CCNB10.72545164
72BRSK10.70717437
73TGFBR10.69985927
74PAK10.68236865
75KSR20.67694646
76PAK20.66061782
77PTK60.65435058
78CDK11A0.64854689
79FLT30.64010347
80ACVR1B0.63944134
81CDK150.62704962
82PRKCI0.61888891
83AKT20.60882968
84CDK180.59860789
85ZAK0.56690031
86DDR20.56555737
87NME20.56387152
88CSNK1D0.55680077
89ARAF0.52249380
90MAP4K10.52048125
91TAOK20.51955352
92ERBB40.51446896
93MAP3K90.50981457
94CLK10.50788343
95CDK140.48906162
96CSNK1E0.47770673
97CSNK2A20.47615853
98EIF2AK20.46889483
99CAMK1D0.45289199
100PRKDC0.45068790
101MAPK140.43231290
102PNCK0.41797588
103MAPK110.41424058
104MAPK10.39153883
105SIK20.38686891
106ILK0.38357605
107AKT10.37529734
108FGFR10.36886688
109RAF10.35311188
110MAP2K20.34979411
111CDK90.34685367
112NTRK10.33509940
113RPS6KA10.33436594
114CSNK2A10.33266064
115VRK10.32234801
116ERN10.31812499
117GSK3B0.31330330
118CAMK1G0.30920703
119FGR0.30543943
120RIPK10.30319045
121MAP3K110.30166580
122PTK20.29291933
123DMPK0.29085959
124DYRK1B0.28555168
125MET0.27935770
126TRPM70.27682578
127UHMK10.27673966
128TESK10.27663749
129RPS6KL10.26725002
130RPS6KC10.26725002

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.28953272
2Mismatch repair_Homo sapiens_hsa034303.89610857
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.20020288
4Spliceosome_Homo sapiens_hsa030403.16168885
5RNA transport_Homo sapiens_hsa030133.13798488
6Cell cycle_Homo sapiens_hsa041103.12420288
7One carbon pool by folate_Homo sapiens_hsa006702.95176270
8Base excision repair_Homo sapiens_hsa034102.81563969
9Homologous recombination_Homo sapiens_hsa034402.46424762
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.42942063
11Nucleotide excision repair_Homo sapiens_hsa034202.42122623
12mRNA surveillance pathway_Homo sapiens_hsa030152.27735167
13Fanconi anemia pathway_Homo sapiens_hsa034602.22796096
14p53 signaling pathway_Homo sapiens_hsa041152.06292080
15Ribosome_Homo sapiens_hsa030101.89771275
16Non-homologous end-joining_Homo sapiens_hsa034501.85475507
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.61023190
18RNA degradation_Homo sapiens_hsa030181.59664832
19RNA polymerase_Homo sapiens_hsa030201.55880707
20MicroRNAs in cancer_Homo sapiens_hsa052061.48141984
21Viral carcinogenesis_Homo sapiens_hsa052031.42365381
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.37177092
23Systemic lupus erythematosus_Homo sapiens_hsa053221.34929279
24Basal transcription factors_Homo sapiens_hsa030221.34707499
25Small cell lung cancer_Homo sapiens_hsa052221.32327280
26Pyrimidine metabolism_Homo sapiens_hsa002401.29983682
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.29440761
28Notch signaling pathway_Homo sapiens_hsa043301.25288224
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23265151
30Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.22516977
31Basal cell carcinoma_Homo sapiens_hsa052171.20961102
32Bladder cancer_Homo sapiens_hsa052191.20274913
33Hippo signaling pathway_Homo sapiens_hsa043901.18734010
34Oocyte meiosis_Homo sapiens_hsa041141.18659160
35HTLV-I infection_Homo sapiens_hsa051661.15202183
36Chronic myeloid leukemia_Homo sapiens_hsa052201.12830525
37mTOR signaling pathway_Homo sapiens_hsa041501.04306517
38Epstein-Barr virus infection_Homo sapiens_hsa051691.04105358
39Colorectal cancer_Homo sapiens_hsa052100.99781186
40Adherens junction_Homo sapiens_hsa045200.99599335
41Biosynthesis of amino acids_Homo sapiens_hsa012300.96624585
42Transcriptional misregulation in cancer_Homo sapiens_hsa052020.93387867
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.92789098
44N-Glycan biosynthesis_Homo sapiens_hsa005100.91925698
45Hedgehog signaling pathway_Homo sapiens_hsa043400.91315890
46Herpes simplex infection_Homo sapiens_hsa051680.90831511
47Thyroid cancer_Homo sapiens_hsa052160.90025466
48Lysine degradation_Homo sapiens_hsa003100.88984559
49Proteasome_Homo sapiens_hsa030500.87698312
50TGF-beta signaling pathway_Homo sapiens_hsa043500.86825605
51Antigen processing and presentation_Homo sapiens_hsa046120.86814044
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.85967999
53Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.80294601
54Selenocompound metabolism_Homo sapiens_hsa004500.79244081
55Non-small cell lung cancer_Homo sapiens_hsa052230.77899251
56Apoptosis_Homo sapiens_hsa042100.77882946
57Galactose metabolism_Homo sapiens_hsa000520.74527647
58Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.72921960
59Proteoglycans in cancer_Homo sapiens_hsa052050.72770609
60Pyruvate metabolism_Homo sapiens_hsa006200.71853993
61Pathways in cancer_Homo sapiens_hsa052000.66905629
62Cyanoamino acid metabolism_Homo sapiens_hsa004600.64292099
63Folate biosynthesis_Homo sapiens_hsa007900.62956132
64Pentose phosphate pathway_Homo sapiens_hsa000300.62048515
65Prostate cancer_Homo sapiens_hsa052150.61394484
66Endometrial cancer_Homo sapiens_hsa052130.61280437
67Pancreatic cancer_Homo sapiens_hsa052120.61024010
68Hepatitis B_Homo sapiens_hsa051610.60365658
69Viral myocarditis_Homo sapiens_hsa054160.59558143
70Acute myeloid leukemia_Homo sapiens_hsa052210.59154275
71Tight junction_Homo sapiens_hsa045300.57341353
72Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.56851086
73ErbB signaling pathway_Homo sapiens_hsa040120.56600406
74Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.56196471
75Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52649811
76Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52359076
77Alcoholism_Homo sapiens_hsa050340.52088100
78Shigellosis_Homo sapiens_hsa051310.51837196
79Focal adhesion_Homo sapiens_hsa045100.51651580
80HIF-1 signaling pathway_Homo sapiens_hsa040660.51525626
81Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51252940
82Insulin signaling pathway_Homo sapiens_hsa049100.51087790
83Prion diseases_Homo sapiens_hsa050200.50775484
84Wnt signaling pathway_Homo sapiens_hsa043100.50445182
85Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49706663
86Melanoma_Homo sapiens_hsa052180.49298679
87Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47961695
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47361827
89Vitamin B6 metabolism_Homo sapiens_hsa007500.46912762
90Steroid biosynthesis_Homo sapiens_hsa001000.46714281
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.46586003
92Purine metabolism_Homo sapiens_hsa002300.46375349
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.45046707
94Fructose and mannose metabolism_Homo sapiens_hsa000510.44336117
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44069366
96Primary immunodeficiency_Homo sapiens_hsa053400.43218156
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.42498558
98Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41606814
99ECM-receptor interaction_Homo sapiens_hsa045120.41521670
100VEGF signaling pathway_Homo sapiens_hsa043700.40781551
101PI3K-Akt signaling pathway_Homo sapiens_hsa041510.39771799
102Cysteine and methionine metabolism_Homo sapiens_hsa002700.39050184
103Legionellosis_Homo sapiens_hsa051340.38775341
104Glioma_Homo sapiens_hsa052140.37589227
105FoxO signaling pathway_Homo sapiens_hsa040680.36321030
106Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.35997392
107AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35857797
108Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35323271
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.32715815
110Renal cell carcinoma_Homo sapiens_hsa052110.32468364
111Sulfur relay system_Homo sapiens_hsa041220.31640968
112B cell receptor signaling pathway_Homo sapiens_hsa046620.30249359
113Measles_Homo sapiens_hsa051620.29884130
114AMPK signaling pathway_Homo sapiens_hsa041520.29808918
115Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29436193
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.27809296
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.27756022
118Carbon metabolism_Homo sapiens_hsa012000.25964975

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