KDF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal epithelial cell development (GO:0060576)6.11418024
2COPI coating of Golgi vesicle (GO:0048205)5.43836754
3Golgi transport vesicle coating (GO:0048200)5.43836754
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.96558934
5desmosome organization (GO:0002934)4.86434898
6intestinal cholesterol absorption (GO:0030299)4.77048516
7protein retention in ER lumen (GO:0006621)4.72153089
8bundle of His cell to Purkinje myocyte communication (GO:0086069)4.69914279
9interferon-gamma secretion (GO:0072643)4.66687904
10glandular epithelial cell differentiation (GO:0002067)4.46053913
11intestinal absorption (GO:0050892)4.42945569
12proline biosynthetic process (GO:0006561)4.26955919
13proline metabolic process (GO:0006560)4.01070639
14exocrine pancreas development (GO:0031017)3.97770353
15COPII vesicle coating (GO:0048208)3.97303617
16endocrine pancreas development (GO:0031018)3.93601157
17hemidesmosome assembly (GO:0031581)3.83835944
18piRNA metabolic process (GO:0034587)3.81474984
19peptide catabolic process (GO:0043171)3.80250735
20nucleoside salvage (GO:0043174)3.66773887
21cysteine metabolic process (GO:0006534)3.65603335
22calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.63943312
23GDP-mannose metabolic process (GO:0019673)3.63810407
24polarized epithelial cell differentiation (GO:0030859)3.62239915
25pyrimidine nucleoside salvage (GO:0043097)3.59140212
26pyrimidine-containing compound salvage (GO:0008655)3.59140212
27sulfur amino acid catabolic process (GO:0000098)3.58840130
28drug transmembrane transport (GO:0006855)3.56438269
29renal absorption (GO:0070293)3.52976531
30erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.47267226
31L-phenylalanine metabolic process (GO:0006558)3.47267226
32pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)3.45646197
33UMP biosynthetic process (GO:0006222)3.45646197
34pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)3.45646197
35UMP metabolic process (GO:0046049)3.45646197
36regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.43706429
37columnar/cuboidal epithelial cell development (GO:0002066)3.34665639
38digestion (GO:0007586)3.28876900
39drug transport (GO:0015893)3.28869237
40respiratory chain complex IV assembly (GO:0008535)3.28812172
41erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.28028493
42L-phenylalanine catabolic process (GO:0006559)3.28028493
43DNA methylation involved in gamete generation (GO:0043046)3.27734480
44proteasome assembly (GO:0043248)3.12354988
45* establishment of skin barrier (GO:0061436)3.11298321
46retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.06373179
47sphingomyelin metabolic process (GO:0006684)3.04744819
48hormone catabolic process (GO:0042447)3.03573610
49NADPH regeneration (GO:0006740)3.01116684
50trophectodermal cell differentiation (GO:0001829)3.00237734
514-hydroxyproline metabolic process (GO:0019471)2.98817610
52* keratinocyte development (GO:0003334)2.98252898
53pteridine-containing compound biosynthetic process (GO:0042559)2.98073241
54regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.96468626
55diterpenoid biosynthetic process (GO:0016102)2.95464638
56activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.94432144
57protein autoprocessing (GO:0016540)2.92762446
58nucleotide salvage (GO:0043173)2.91171381
59urate metabolic process (GO:0046415)2.90789648
60negative regulation of cell fate commitment (GO:0010454)2.88241714
61UDP-N-acetylglucosamine metabolic process (GO:0006047)2.85191340
62* regulation of water loss via skin (GO:0033561)2.85088958
63positive regulation of nuclease activity (GO:0032075)2.84876098
64homocysteine metabolic process (GO:0050667)2.84267507
65glutathione derivative metabolic process (GO:1901685)2.83840124
66glutathione derivative biosynthetic process (GO:1901687)2.83840124
67pyrimidine-containing compound transmembrane transport (GO:0072531)2.81849584
68glucose catabolic process (GO:0006007)2.80174882
69tight junction assembly (GO:0070830)2.77332797
70pentose-phosphate shunt (GO:0006098)2.76508700
71DNA replication checkpoint (GO:0000076)2.75927629
72folic acid metabolic process (GO:0046655)2.75811130
73ribosome assembly (GO:0042255)2.74396748
74signal transduction involved in regulation of gene expression (GO:0023019)2.73672120
75peptide hormone processing (GO:0016486)2.72512649
76vitamin transport (GO:0051180)2.72277983
77serine family amino acid metabolic process (GO:0009069)2.72257021
78L-alpha-amino acid transmembrane transport (GO:1902475)2.71519958
79lysine catabolic process (GO:0006554)2.70383347
80lysine metabolic process (GO:0006553)2.70383347
81cytochrome complex assembly (GO:0017004)2.69490741
82cardiac right ventricle morphogenesis (GO:0003215)2.67876337
83serine family amino acid catabolic process (GO:0009071)2.67440491
84nucleotide-sugar biosynthetic process (GO:0009226)2.66473027
85SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.66086703
86regulation of cholesterol homeostasis (GO:2000188)2.65383617
87regulation of nuclease activity (GO:0032069)2.63423578
88pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.63389246
89transcytosis (GO:0045056)2.63253502
90diol metabolic process (GO:0034311)2.61954883
91regulation of posttranscriptional gene silencing (GO:0060147)2.61953798
92regulation of gene silencing by miRNA (GO:0060964)2.61953798
93regulation of gene silencing by RNA (GO:0060966)2.61953798
94modified amino acid transport (GO:0072337)2.61603151
95positive regulation of glycoprotein biosynthetic process (GO:0010560)2.61306743
96establishment or maintenance of monopolar cell polarity (GO:0061339)2.60796463
97establishment of monopolar cell polarity (GO:0061162)2.60796463
98transcription from mitochondrial promoter (GO:0006390)2.60041494
99cobalamin metabolic process (GO:0009235)2.59666435
100regulation of apoptotic process involved in morphogenesis (GO:1902337)2.59652627
101protein targeting to ER (GO:0045047)2.58771165
102regulation of translational termination (GO:0006449)2.57874642
103signal peptide processing (GO:0006465)2.57631282
104glycine metabolic process (GO:0006544)2.57585854
105positive regulation of glycoprotein metabolic process (GO:1903020)2.57141812
106sphingosine metabolic process (GO:0006670)2.56332276
107cotranslational protein targeting to membrane (GO:0006613)2.55387851
108rRNA modification (GO:0000154)2.53649226
109formation of translation preinitiation complex (GO:0001731)2.53647489
110gap junction assembly (GO:0016264)2.53320417
111keratinocyte proliferation (GO:0043616)2.53182490
112endoplasmic reticulum unfolded protein response (GO:0030968)2.52374085
113nucleoside transmembrane transport (GO:1901642)2.51219089
114cellular response to vitamin D (GO:0071305)2.50531926
115purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.50289932
1163-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.50289932
117pentose metabolic process (GO:0019321)2.50036217
118folic acid-containing compound biosynthetic process (GO:0009396)2.49864733
119rRNA methylation (GO:0031167)2.49030407
120response to nitrosative stress (GO:0051409)2.48362835
121flavonoid metabolic process (GO:0009812)2.46539299
122positive regulation of Cdc42 GTPase activity (GO:0043089)2.46226850
123nucleoside transport (GO:0015858)2.45807330
124* multicellular organismal water homeostasis (GO:0050891)2.44778065
125drug catabolic process (GO:0042737)2.44176087
126cellular response to unfolded protein (GO:0034620)2.43992625
127NADH metabolic process (GO:0006734)2.43780301
128regulation of hippo signaling (GO:0035330)2.43198748
129establishment of protein localization to endoplasmic reticulum (GO:0072599)2.43139478
130lactate metabolic process (GO:0006089)2.43118555
131negative regulation of cell fate specification (GO:0009996)2.42933972
132male meiosis I (GO:0007141)2.42492265
133protein localization to endoplasmic reticulum (GO:0070972)2.42478469
134valine metabolic process (GO:0006573)2.42018974
135protein maturation by protein folding (GO:0022417)2.39687305
136cellular modified amino acid catabolic process (GO:0042219)2.39639853
137branched-chain amino acid catabolic process (GO:0009083)2.39591236
138bile acid and bile salt transport (GO:0015721)2.38965437
139branched-chain amino acid metabolic process (GO:0009081)2.38704058
140* negative regulation of keratinocyte proliferation (GO:0010839)2.38588791
141cellular response to topologically incorrect protein (GO:0035967)2.38405647
142nodal signaling pathway (GO:0038092)2.38315748
143establishment of integrated proviral latency (GO:0075713)2.37237223
144establishment of apical/basal cell polarity (GO:0035089)2.37144976
145pteridine-containing compound metabolic process (GO:0042558)2.37077348
146regulation of cellular amino acid metabolic process (GO:0006521)2.36739357
147oocyte development (GO:0048599)2.36366693
148pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.36095754
149regulation of chemokine secretion (GO:0090196)2.36048489
150L-ascorbic acid metabolic process (GO:0019852)2.34710394
151L-serine metabolic process (GO:0006563)2.34160932
152pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.33330317
153negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.32655753
154purine ribonucleotide transport (GO:0015868)2.31696548
155ectoderm development (GO:0007398)2.31545176
156phenylpropanoid metabolic process (GO:0009698)2.31056575
157biotin metabolic process (GO:0006768)2.30098099
158synapsis (GO:0007129)2.28453671
159water-soluble vitamin biosynthetic process (GO:0042364)2.27769669
160CTP biosynthetic process (GO:0006241)2.26653609
161CTP metabolic process (GO:0046036)2.26653609
162regulation of bile acid biosynthetic process (GO:0070857)2.26198350
163terpenoid biosynthetic process (GO:0016114)2.26152603
164* water homeostasis (GO:0030104)2.25958983
165regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.25728470
166negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.24362491
167regulation of cardioblast differentiation (GO:0051890)2.22371457
168negative regulation of ligase activity (GO:0051352)2.21083276
169negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.21083276
170epithelial cell maturation (GO:0002070)2.20910373
171phosphate ion homeostasis (GO:0055062)2.20796559
172trivalent inorganic anion homeostasis (GO:0072506)2.20796559
173notochord development (GO:0030903)2.20443347
174dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.18661243
175vitamin transmembrane transport (GO:0035461)2.18515292
176NADP metabolic process (GO:0006739)2.16366755
177regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.16218354
178pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.15324702
179epithelial cell-cell adhesion (GO:0090136)2.14918887
180positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.13312256
181pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.13221970

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.87008147
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.59490850
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.22731401
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.21863973
5E2F7_22180533_ChIP-Seq_HELA_Human3.05667248
6PPARA_22158963_ChIP-Seq_LIVER_Mouse2.80055686
7RXR_22158963_ChIP-Seq_LIVER_Mouse2.67153467
8TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.56721943
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.40609798
10SOX2_27498859_Chip-Seq_STOMACH_Mouse2.30936439
11ESR1_21235772_ChIP-Seq_MCF-7_Human2.14242808
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.11834684
13CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.05326692
14STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.01703762
15GATA6_25053715_ChIP-Seq_YYC3_Human2.00471348
16GATA4_25053715_ChIP-Seq_YYC3_Human2.00099758
17POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.92182714
18ZNF263_19887448_ChIP-Seq_K562_Human1.91545071
19LXR_22158963_ChIP-Seq_LIVER_Mouse1.90390426
20EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.89405654
21PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.86333978
22MYC_19079543_ChIP-ChIP_MESCs_Mouse1.83418719
23AR_21909140_ChIP-Seq_LNCAP_Human1.82767862
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.77193461
25GABP_17652178_ChIP-ChIP_JURKAT_Human1.69771623
26KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.69246475
27TCF3_18692474_ChIP-Seq_MEFs_Mouse1.66291882
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.65292775
29FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.63027460
30JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.62856608
31STAT3_1855785_ChIP-Seq_MESCs_Mouse1.61555220
32ESR2_21235772_ChIP-Seq_MCF-7_Human1.60736358
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.60058101
34E2F1_18555785_ChIP-Seq_MESCs_Mouse1.59969981
35MYC_19030024_ChIP-ChIP_MESCs_Mouse1.55947204
36PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.55448887
37EGR1_23403033_ChIP-Seq_LIVER_Mouse1.55066096
38ESR1_15608294_ChIP-ChIP_MCF-7_Human1.54187038
39THAP11_20581084_ChIP-Seq_MESCs_Mouse1.52626910
40FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.51374488
41CDX2_20551321_ChIP-Seq_CACO-2_Human1.51091126
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49166087
43SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.48300987
44ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.48040054
45NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.47394771
46CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.46878387
47KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.45985645
48ETS1_20019798_ChIP-Seq_JURKAT_Human1.45441992
49NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.44169194
50NELFA_20434984_ChIP-Seq_ESCs_Mouse1.44134251
51TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.43603979
52PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.42545713
53ATF3_27146783_Chip-Seq_COLON_Human1.40905031
54EST1_17652178_ChIP-ChIP_JURKAT_Human1.39699555
55SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.39419334
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.39369428
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.38740182
58CREB1_15753290_ChIP-ChIP_HEK293T_Human1.36788689
59SOX2_20726797_ChIP-Seq_SW620_Human1.35192908
60KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.34556379
61RACK7_27058665_Chip-Seq_MCF-7_Human1.32294786
62PADI4_21655091_ChIP-ChIP_MCF-7_Human1.30513503
63TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.28019244
64ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.27644150
65ELF5_23300383_ChIP-Seq_T47D_Human1.25549299
66KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.24901988
67KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.24901988
68KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.24901988
69ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24307600
70SOX2_18692474_ChIP-Seq_MEFs_Mouse1.23700717
71P63_26484246_Chip-Seq_KERATINOCYTES_Human1.22902133
72XRN2_22483619_ChIP-Seq_HELA_Human1.22891204
73CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.22498472
74EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.21907226
75KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.18187487
76DCP1A_22483619_ChIP-Seq_HELA_Human1.16149401
77ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16143445
78SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.15060616
79KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14077490
80TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.13610255
81ZFX_18555785_ChIP-Seq_MESCs_Mouse1.13535494
82TTF2_22483619_ChIP-Seq_HELA_Human1.13248420
83ESR1_20079471_ChIP-ChIP_T-47D_Human1.13154350
84RARG_19884340_ChIP-ChIP_MEFs_Mouse1.13135472
85CLOCK_20551151_ChIP-Seq_293T_Human1.12991021
86FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.12961659
87SRF_21415370_ChIP-Seq_HL-1_Mouse1.12013250
88CHD1_26751641_Chip-Seq_LNCaP_Human1.11776965
89TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11157844
90GATA3_24758297_ChIP-Seq_MCF-7_Human1.08876814
91PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08095886
92OCT4_18692474_ChIP-Seq_MEFs_Mouse1.07337703
93RUNX1_27514584_Chip-Seq_MCF-7_Human1.06587198
94POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05607114
95GABP_19822575_ChIP-Seq_HepG2_Human1.05139117
96FOXP3_21729870_ChIP-Seq_TREG_Human1.05110563
97MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.05069129
98DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.05068953
99NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.04611383
100SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.04336276
101SRY_22984422_ChIP-ChIP_TESTIS_Rat1.03557384
102KDM5A_27292631_Chip-Seq_BREAST_Human1.02986651
103FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.02355032
104TCF3_18692474_ChIP-Seq_MESCs_Mouse1.02305593
105ELK1_22589737_ChIP-Seq_MCF10A_Human1.02101772
106FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.01623341
107FOXM1_23109430_ChIP-Seq_U2OS_Human1.01085402
108POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.98310422
109EGR1_19374776_ChIP-ChIP_THP-1_Human0.98172697
110ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.98027855
111NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.97630301
112NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.96798051
113YY1_21170310_ChIP-Seq_MESCs_Mouse0.96143395
114CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.95655486
115HIF1A_21447827_ChIP-Seq_MCF-7_Human0.94967620
116NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.94864290
117SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.94150426
118RARB_24833708_ChIP-Seq_LIVER_Mouse0.94083863
119ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.93519142
120ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93343836
121E2F1_21310950_ChIP-Seq_MCF-7_Human0.92811042
122TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92756705
123SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.91772616
124FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.90967453
125FOXO3_23340844_ChIP-Seq_DLD1_Human0.90644491
126CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90643576
127KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89493028
128BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.88361851
129NANOG_18692474_ChIP-Seq_MEFs_Mouse0.88253850

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle3.93849997
2MP0005360_urolithiasis3.27047018
3MP0004264_abnormal_extraembryonic_tissu3.22575297
4MP0001666_abnormal_nutrient_absorption3.15187332
5MP0005365_abnormal_bile_salt2.95637923
6MP0002139_abnormal_hepatobiliary_system2.89523705
7MP0008877_abnormal_DNA_methylation2.84125888
8MP0005085_abnormal_gallbladder_physiolo2.72119377
9MP0004019_abnormal_vitamin_homeostasis2.56305173
10MP0004043_abnormal_pH_regulation2.52999553
11MP0003693_abnormal_embryo_hatching2.41695737
12MP0002254_reproductive_system_inflammat2.38039143
13MP0002796_impaired_skin_barrier2.21542825
14MP0000678_abnormal_parathyroid_gland2.21375512
15MP0005220_abnormal_exocrine_pancreas2.17692117
16MP0003195_calcinosis2.11771952
17MP0002098_abnormal_vibrissa_morphology2.06329987
18MP0003283_abnormal_digestive_organ2.05445751
19MP0005083_abnormal_biliary_tract2.03728577
20MP0000566_synostosis1.97418983
21MP0003123_paternal_imprinting1.93349848
22MP0008875_abnormal_xenobiotic_pharmacok1.91666087
23MP0000537_abnormal_urethra_morphology1.88628171
24MP0009643_abnormal_urine_homeostasis1.87531894
25MP0002877_abnormal_melanocyte_morpholog1.85494401
26MP0010352_gastrointestinal_tract_polyps1.79471852
27MP0000462_abnormal_digestive_system1.73034040
28MP0005332_abnormal_amino_acid1.71432913
29MP0002138_abnormal_hepatobiliary_system1.70656482
30MP0003806_abnormal_nucleotide_metabolis1.66568810
31MP0004957_abnormal_blastocyst_morpholog1.65756529
32MP0003941_abnormal_skin_development1.64390900
33MP0002909_abnormal_adrenal_gland1.57155947
34MP0000579_abnormal_nail_morphology1.54622464
35MP0001849_ear_inflammation1.48637580
36MP0003252_abnormal_bile_duct1.47594102
37MP0001756_abnormal_urination1.45731763
38MP0002163_abnormal_gland_morphology1.45213463
39MP0003705_abnormal_hypodermis_morpholog1.44931370
40MP0001944_abnormal_pancreas_morphology1.44074851
41MP0000427_abnormal_hair_cycle1.41537575
42MP0000613_abnormal_salivary_gland1.39855860
43MP0002693_abnormal_pancreas_physiology1.39643783
44MP0003868_abnormal_feces_composition1.38046139
45MP0005501_abnormal_skin_physiology1.36013455
46MP0008058_abnormal_DNA_repair1.31949948
47MP0003183_abnormal_peptide_metabolism1.31089267
48MP0001765_abnormal_ion_homeostasis1.30742714
49MP0010678_abnormal_skin_adnexa1.29295486
50MP0010771_integument_phenotype1.28637836
51MP0004782_abnormal_surfactant_physiolog1.28401145
52MP0001216_abnormal_epidermal_layer1.27709651
53MP0003453_abnormal_keratinocyte_physiol1.26966533
54MP0009672_abnormal_birth_weight1.26624576
55MP0000647_abnormal_sebaceous_gland1.25507462
56MP0008057_abnormal_DNA_replication1.23379027
57MP0001873_stomach_inflammation1.18967673
58MP0005084_abnormal_gallbladder_morpholo1.18867556
59MP0010030_abnormal_orbit_morphology1.18782725
60MP0000490_abnormal_crypts_of1.17331352
61MP0009840_abnormal_foam_cell1.17197500
62MP0005636_abnormal_mineral_homeostasis1.16140617
63MP0002060_abnormal_skin_morphology1.15753233
64MP0009053_abnormal_anal_canal1.14599319
65MP0000467_abnormal_esophagus_morphology1.11572767
66MP0000538_abnormal_urinary_bladder1.10543546
67MP0003787_abnormal_imprinting1.10404563
68MP0005408_hypopigmentation1.09878946
69MP0000627_abnormal_mammary_gland1.08994335
70MP0003111_abnormal_nucleus_morphology1.07435961
71MP0003119_abnormal_digestive_system1.06943183
72MP0003890_abnormal_embryonic-extraembry1.06851855
73MP0001661_extended_life_span1.05486345
74MP0004381_abnormal_hair_follicle1.05340031
75MP0005075_abnormal_melanosome_morpholog1.04585436
76MP0003878_abnormal_ear_physiology1.04322072
77MP0005377_hearing/vestibular/ear_phenot1.04322072
78MP0001881_abnormal_mammary_gland1.02951453
79MP0000762_abnormal_tongue_morphology1.02861739
80MP0000013_abnormal_adipose_tissue1.01847468
81MP0010094_abnormal_chromosome_stability1.01503083
82MP0003866_abnormal_defecation1.01236237
83MP0000477_abnormal_intestine_morphology1.00274504
84MP0003718_maternal_effect0.97896868
85MP0000383_abnormal_hair_follicle0.96049056
86MP0000470_abnormal_stomach_morphology0.95464335
87MP0002136_abnormal_kidney_physiology0.95010677
88MP0001664_abnormal_digestion0.93941551
89MP0001346_abnormal_lacrimal_gland0.92748217
90MP0010386_abnormal_urinary_bladder0.92526380
91MP0003300_gastrointestinal_ulcer0.91157367
92MP0010329_abnormal_lipoprotein_level0.88744321
93MP0002210_abnormal_sex_determination0.88363027
94MP0000377_abnormal_hair_follicle0.88297324
95MP0000003_abnormal_adipose_tissue0.88207253
96MP0003077_abnormal_cell_cycle0.86708095
97MP0001764_abnormal_homeostasis0.85735796
98MP0005379_endocrine/exocrine_gland_phen0.84989877
99MP0003315_abnormal_perineum_morphology0.84238530
100MP0000516_abnormal_urinary_system0.83435490
101MP0005367_renal/urinary_system_phenotyp0.83435490
102MP0004133_heterotaxia0.82430294
103MP0003186_abnormal_redox_activity0.81977651
104MP0008932_abnormal_embryonic_tissue0.81895404
105MP0009780_abnormal_chondrocyte_physiolo0.80691486
106MP0005451_abnormal_body_composition0.79850543
107MP0006292_abnormal_olfactory_placode0.79818578
108MP0001188_hyperpigmentation0.79782942
109MP0001145_abnormal_male_reproductive0.78509293
110MP0002234_abnormal_pharynx_morphology0.78481831
111MP0008789_abnormal_olfactory_epithelium0.77876787
112MP0000367_abnormal_coat/_hair0.77159233
113MP0002118_abnormal_lipid_homeostasis0.76196923
114MP0001672_abnormal_embryogenesis/_devel0.75045289
115MP0005380_embryogenesis_phenotype0.75045289
116MP0001727_abnormal_embryo_implantation0.74072428
117MP0010155_abnormal_intestine_physiology0.73821233
118MP0001929_abnormal_gametogenesis0.73759151
119MP0002928_abnormal_bile_duct0.73564628
120MP0002084_abnormal_developmental_patter0.73181564
121MP0002078_abnormal_glucose_homeostasis0.72390661
122MP0003936_abnormal_reproductive_system0.72082580
123MP0000609_abnormal_liver_physiology0.71737816
124MP0003786_premature_aging0.71632352
125MP0008872_abnormal_physiological_respon0.71590191
126MP0002111_abnormal_tail_morphology0.71435502
127MP0001730_embryonic_growth_arrest0.71424057
128MP0002277_abnormal_respiratory_mucosa0.70725350
129MP0005395_other_phenotype0.70439980
130MP0003566_abnormal_cell_adhesion0.70204693
131MP0002085_abnormal_embryonic_tissue0.69942376
132MP0002160_abnormal_reproductive_system0.69881409
133MP0000653_abnormal_sex_gland0.69678420
134MP0009379_abnormal_foot_pigmentation0.69117882
135MP0008004_abnormal_stomach_pH0.67220494
136MP0005381_digestive/alimentary_phenotyp0.66309726
137MP0005076_abnormal_cell_differentiation0.64270755
138MP0005248_abnormal_Harderian_gland0.64159055

Predicted human phenotypes

RankGene SetZ-score
1Gout (HP:0001997)4.39253717
2Hypoglycemic coma (HP:0001325)4.36683819
3Right ventricular cardiomyopathy (HP:0011663)3.96296926
4Hyperactive renin-angiotensin system (HP:0000841)3.72469536
5Pili torti (HP:0003777)3.68198991
6Onycholysis (HP:0001806)3.66123397
7Hypoglycemic seizures (HP:0002173)3.65501773
8Abnormality of aromatic amino acid family metabolism (HP:0004338)3.64904349
9Hyperinsulinemic hypoglycemia (HP:0000825)3.61973755
10Abnormality of chloride homeostasis (HP:0011422)3.61966740
11Symptomatic seizures (HP:0011145)3.61124064
12Hyperglycinuria (HP:0003108)3.41378943
13Hyperglycemia (HP:0003074)3.36749396
14Ketoacidosis (HP:0001993)3.34436889
15Palmoplantar hyperkeratosis (HP:0000972)3.20038358
16Late onset (HP:0003584)3.19578864
17Fragile nails (HP:0001808)3.14712362
18Abnormality of purine metabolism (HP:0004352)3.11909393
19Intrahepatic cholestasis (HP:0001406)3.10969912
20Lip pit (HP:0100267)3.04705932
21Abnormal pancreas size (HP:0012094)3.02122081
22Abnormality of glutamine family amino acid metabolism (HP:0010902)2.99458721
23Generalized aminoaciduria (HP:0002909)2.99181017
24Proximal tubulopathy (HP:0000114)2.98477698
25Palmar hyperkeratosis (HP:0010765)2.96337852
26Abnormality of monocarboxylic acid metabolism (HP:0010996)2.96170335
27Milia (HP:0001056)2.93618310
28Septate vagina (HP:0001153)2.91769857
29Abdominal distention (HP:0003270)2.87813575
30Malnutrition (HP:0004395)2.81887255
31Fat malabsorption (HP:0002630)2.76420200
32Woolly hair (HP:0002224)2.76066387
33Abnormality of glycine metabolism (HP:0010895)2.74559136
34Abnormality of serine family amino acid metabolism (HP:0010894)2.74559136
35Ketosis (HP:0001946)2.73723525
36Hyperuricemia (HP:0002149)2.73393810
37Increased purine levels (HP:0004368)2.73393810
38Vacuolated lymphocytes (HP:0001922)2.69477857
39Hyperglycinemia (HP:0002154)2.68212917
40Hypokinesia (HP:0002375)2.66475900
41Abnormal biliary tract morphology (HP:0012440)2.61643698
42Conjugated hyperbilirubinemia (HP:0002908)2.59773948
43Ileus (HP:0002595)2.53001800
44Abnormality of nucleobase metabolism (HP:0010932)2.52673999
45Hypokalemic alkalosis (HP:0001949)2.51757554
46Plantar hyperkeratosis (HP:0007556)2.50698037
47Alopecia of scalp (HP:0002293)2.49051414
48Abnormality of the distal phalanges of the toes (HP:0010182)2.45541376
49Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.44522010
50Pterygium (HP:0001059)2.43483808
51Abnormality of nail color (HP:0100643)2.43201661
52Abnormality of the intrinsic pathway (HP:0010989)2.42794052
53Unilateral renal agenesis (HP:0000122)2.40419647
54Renal salt wasting (HP:0000127)2.40257502
55Abnormality of proline metabolism (HP:0010907)2.38506727
56Hydroxyprolinuria (HP:0003080)2.38506727
57Abnormality of urine glucose concentration (HP:0011016)2.38166794
58Glycosuria (HP:0003076)2.38166794
59Abnormal hemoglobin (HP:0011902)2.33777882
60Abnormal hair laboratory examination (HP:0003328)2.31203497
61Trismus (HP:0000211)2.29724046
62Insulin resistance (HP:0000855)2.29461201
63Abnormality of permanent molar morphology (HP:0011071)2.28027957
64Abnormality of the dental root (HP:0006486)2.28027957
65Taurodontia (HP:0000679)2.28027957
66Hypotrichosis (HP:0001006)2.28018505
67Popliteal pterygium (HP:0009756)2.27153724
68Abnormality of endocrine pancreas physiology (HP:0012093)2.27088913
69Abnormality of the pancreatic islet cells (HP:0006476)2.27088913
70Amelogenesis imperfecta (HP:0000705)2.23212640
71Abnormality of the salivary glands (HP:0010286)2.22289227
72Abnormality of the labia minora (HP:0012880)2.20818117
73Dicarboxylic aciduria (HP:0003215)2.17710223
74Abnormality of dicarboxylic acid metabolism (HP:0010995)2.17710223
75Abnormality of sulfur amino acid metabolism (HP:0004339)2.16157328
76Poor suck (HP:0002033)2.16113696
77Abnormality of renin-angiotensin system (HP:0000847)2.16006969
78Hypokalemia (HP:0002900)2.15934551
79Aplasia/hypoplasia of the uterus (HP:0008684)2.15411492
80Widely patent fontanelles and sutures (HP:0004492)2.14611097
81Alkalosis (HP:0001948)2.13965933
82Congenital ichthyosiform erythroderma (HP:0007431)2.13208630
83Hyperammonemia (HP:0001987)2.12833427
84Abnormality of fatty-acid metabolism (HP:0004359)2.12724057
85Exocrine pancreatic insufficiency (HP:0001738)2.12350260
86Tetany (HP:0001281)2.11997953
87Dehydration (HP:0001944)2.11791808
88Abnormality of renal excretion (HP:0011036)2.11195208
89Sensory axonal neuropathy (HP:0003390)2.09777306
90Steatorrhea (HP:0002570)2.07603344
91Absent eyebrow (HP:0002223)2.07518928
92Abnormality of vitamin metabolism (HP:0100508)2.07498446
93Hypoplasia of the uterus (HP:0000013)2.07417647
94Insulin-resistant diabetes mellitus (HP:0000831)2.07398263
95Metabolic alkalosis (HP:0200114)2.07323228
96Biliary tract neoplasm (HP:0100574)2.06934235
97Hypoplasia of dental enamel (HP:0006297)2.05730909
98Lethargy (HP:0001254)2.03762952
99Absent eyelashes (HP:0000561)2.03129327
100Atrophic scars (HP:0001075)2.02863597
101Esophageal varix (HP:0002040)2.02572629
102Micronodular cirrhosis (HP:0001413)2.02535817
103Enlarged penis (HP:0000040)2.02466474
104Abnormality of molar (HP:0011077)2.01642028
105Abnormality of molar morphology (HP:0011070)2.01642028
106Type I transferrin isoform profile (HP:0003642)2.00216505
107Oral leukoplakia (HP:0002745)1.96597871
108Progressive hearing impairment (HP:0001730)1.96466067
109Breast carcinoma (HP:0003002)1.95896233
110Abnormality of the labia majora (HP:0012881)1.95114543
111Abnormality of the dental pulp (HP:0006479)1.94851721
112Megaloblastic anemia (HP:0001889)1.93088507
113Abnormality of the gastric mucosa (HP:0004295)1.93032052
114Xanthomatosis (HP:0000991)1.91087098
115Hyperphosphatemia (HP:0002905)1.90616933
116Hypoplasia of the pons (HP:0012110)1.89980714
117Congenital malformation of the right heart (HP:0011723)1.89273628
118Double outlet right ventricle (HP:0001719)1.89273628
119Abnormality of vitamin B metabolism (HP:0004340)1.89128636
120Increased circulating renin level (HP:0000848)1.89036738
121Sparse eyelashes (HP:0000653)1.88672149
122Prominent metopic ridge (HP:0005487)1.88298998
123Hypoplastic labia majora (HP:0000059)1.87323220
124Abnormality of calcium-phosphate metabolism (HP:0100530)1.87243038
125Abnormality of small intestinal villus morphology (HP:0011472)1.87155823
126Villous atrophy (HP:0011473)1.87155823
127Chronic bronchitis (HP:0004469)1.86801370
128Hyperparathyroidism (HP:0000843)1.85698076
129Hypoplastic female external genitalia (HP:0012815)1.84427668
130Abnormality of magnesium homeostasis (HP:0004921)1.83805044
131Abnormality of methionine metabolism (HP:0010901)1.83685526
132Abnormality of the labia (HP:0000058)1.83317371
133Hyperphosphaturia (HP:0003109)1.81518758
134Hypomagnesemia (HP:0002917)1.81518261
135Hypotension (HP:0002615)1.81505547
136Tongue fasciculations (HP:0001308)1.80198247
137Neonatal death (HP:0003811)1.80011889
138Abnormality of aspartate family amino acid metabolism (HP:0010899)1.79934476
139Labial hypoplasia (HP:0000066)1.79306503
140Microvesicular hepatic steatosis (HP:0001414)1.78168468
141Selective tooth agenesis (HP:0001592)1.77826431
142Abnormality of the preputium (HP:0100587)1.76716903
143Concave nail (HP:0001598)1.76339580
144Abnormality of the pons (HP:0007361)1.71505555
145Nail dystrophy (HP:0008404)1.70272077
146Diminished movement (HP:0002374)1.69868679
147Angiofibromas (HP:0010615)1.68083890
148Adenoma sebaceum (HP:0009720)1.68083890
149Absent hair (HP:0002298)1.67450008
150Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.66528359
151Abnormal protein N-linked glycosylation (HP:0012347)1.66528359
152Abnormal protein glycosylation (HP:0012346)1.66528359
153Abnormal glycosylation (HP:0012345)1.66528359
154Curly hair (HP:0002212)1.66012604
155Urethral obstruction (HP:0000796)1.65354642
156Ependymoma (HP:0002888)1.64245680
157Dry hair (HP:0011359)1.61875829

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA25.52898011
2FRK3.65301282
3MAPK153.32601909
4BCKDK3.32600175
5ERN13.20773723
6STK38L2.88099354
7WNK42.82466868
8PASK2.50791607
9NME12.49221582
10RPS6KB22.42619831
11INSRR2.33210609
12TNIK2.32817372
13MAP2K22.29841294
14LATS12.18594562
15MAP3K32.15290120
16MAP3K22.11372636
17MST42.09109621
18WNK32.07009210
19VRK21.99808182
20MUSK1.97537793
21MAP3K91.97224587
22TTK1.79377694
23FGFR21.72668604
24SMG11.67538462
25FER1.65315262
26IRAK31.51924221
27PTK61.50409982
28EIF2AK11.47780202
29PRKCI1.40945284
30TESK11.28894793
31BUB11.28064374
32MAPKAPK31.26668603
33PIK3CG1.26493308
34PTK21.26328828
35ACVR1B1.24311839
36AKT31.23320844
37DYRK1B1.22210329
38MAP3K121.16552065
39MST1R1.16446800
40MAP3K111.12584493
41SIK11.11390318
42TRIM281.08732785
43STK241.04950173
44STK161.03994810
45PAK40.97191844
46PLK30.94917675
47GRK10.94140895
48PLK40.92240403
49CDK120.90973643
50TAF10.90352295
51AURKB0.89672531
52FGFR40.87952488
53CDK70.86299632
54ZAK0.85854837
55EIF2AK30.83989306
56MAP2K60.82314780
57PRKG20.81747421
58MET0.81739836
59NEK60.80447393
60BRSK10.79391339
61NEK10.79231405
62TAOK30.77810822
63STK100.77006663
64FLT30.75368619
65EPHB20.75287671
66MKNK20.75172305
67PKN20.74835385
68TGFBR10.73526602
69NLK0.72817419
70PRKD30.72211127
71LMTK20.71447041
72BMX0.71039998
73HIPK20.70081955
74CDK80.68668825
75AURKA0.67636234
76PHKG10.67509008
77PHKG20.67509008
78ILK0.65146432
79LRRK20.65144793
80RPS6KA40.63859785
81PLK10.63719847
82DYRK30.63273005
83NEK20.62830735
84RIPK10.62089752
85PNCK0.61729112
86IRAK10.60194669
87STK40.59662510
88PBK0.59079822
89MAP3K80.58679680
90MAPK110.57768021
91BRSK20.56652222
92WEE10.56190223
93CHUK0.56185272
94BRAF0.55486690
95BMPR1B0.54168343
96PDK40.53931320
97PDK30.53931320
98SCYL20.53312562
99MAP3K10.50411622
100MTOR0.49516944
101STK30.49125656
102PDK20.48056971
103PRKD20.47885802
104NME20.47595454
105SRPK10.47010474
106DAPK10.46863650
107FGFR10.46741526
108MELK0.46523792
109STK390.44506823
110NUAK10.44436287
111MAP2K10.44158911
112CDC42BPA0.43951934
113TAOK10.43251126
114ERBB20.43244174
115ERBB40.42457821
116EPHA30.42078128
117TRIB30.41888507
118CDC70.41493204
119CSNK1E0.41296557
120ARAF0.41052320
121PRKCE0.40906915
122CDK40.40392547
123CSNK2A20.39402307
124CHEK10.37643866
125CSNK2A10.36981849
126VRK10.36790672
127CSNK1G10.36789939
128AKT20.36673917
129MAP3K100.36128190
130CHEK20.35839260
131CDK60.34909128
132TSSK60.34085633
133LIMK10.33087226
134OXSR10.32625287
135BCR0.31302145
136ATM0.30201773
137ATR0.29285608
138EEF2K0.29014687
139RPS6KA10.28427946
140GSK3A0.26571270

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049505.27637881
2Sulfur metabolism_Homo sapiens_hsa009203.07865044
3Protein export_Homo sapiens_hsa030602.70672248
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.69609605
5Folate biosynthesis_Homo sapiens_hsa007902.67243856
6Fat digestion and absorption_Homo sapiens_hsa049752.51838231
7Cyanoamino acid metabolism_Homo sapiens_hsa004602.29265382
8Vitamin B6 metabolism_Homo sapiens_hsa007502.21933273
9Pentose and glucuronate interconversions_Homo sapiens_hsa000402.12784142
10Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.96044366
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.94830145
12Selenocompound metabolism_Homo sapiens_hsa004501.91257342
13Glutathione metabolism_Homo sapiens_hsa004801.88126213
14Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.81555814
15Histidine metabolism_Homo sapiens_hsa003401.78637562
16Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.78242889
17Tryptophan metabolism_Homo sapiens_hsa003801.75274108
18Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.65529953
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.65265432
20Vitamin digestion and absorption_Homo sapiens_hsa049771.60040995
21Fatty acid degradation_Homo sapiens_hsa000711.57918729
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.55890203
23Drug metabolism - other enzymes_Homo sapiens_hsa009831.54727712
24Chemical carcinogenesis_Homo sapiens_hsa052041.50748966
25DNA replication_Homo sapiens_hsa030301.50613125
26Phenylalanine metabolism_Homo sapiens_hsa003601.50335533
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.42928444
28Ribosome_Homo sapiens_hsa030101.40200423
29Protein digestion and absorption_Homo sapiens_hsa049741.34416716
30Non-homologous end-joining_Homo sapiens_hsa034501.34121751
31Galactose metabolism_Homo sapiens_hsa000521.33372174
32alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.31948570
33Linoleic acid metabolism_Homo sapiens_hsa005911.31456127
34beta-Alanine metabolism_Homo sapiens_hsa004101.29726748
35Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.29037006
36Butanoate metabolism_Homo sapiens_hsa006501.27317147
37Peroxisome_Homo sapiens_hsa041461.23488213
38Propanoate metabolism_Homo sapiens_hsa006401.20810532
39Arginine and proline metabolism_Homo sapiens_hsa003301.19998929
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.18770092
41Fructose and mannose metabolism_Homo sapiens_hsa000511.18279263
42One carbon pool by folate_Homo sapiens_hsa006701.15916592
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.15161885
44Pancreatic secretion_Homo sapiens_hsa049721.12354266
45Retinol metabolism_Homo sapiens_hsa008301.05366231
46Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.05242197
47Arachidonic acid metabolism_Homo sapiens_hsa005901.03530097
48Starch and sucrose metabolism_Homo sapiens_hsa005001.02385395
49Cysteine and methionine metabolism_Homo sapiens_hsa002701.01460804
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.00936861
51Other glycan degradation_Homo sapiens_hsa005111.00657212
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00463039
53RNA polymerase_Homo sapiens_hsa030200.99997076
54Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.96189012
55Proteasome_Homo sapiens_hsa030500.94937329
56Basal transcription factors_Homo sapiens_hsa030220.94896314
57Homologous recombination_Homo sapiens_hsa034400.94690838
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.94500161
59Sulfur relay system_Homo sapiens_hsa041220.90568664
60Pyruvate metabolism_Homo sapiens_hsa006200.88790970
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.88727194
62Mineral absorption_Homo sapiens_hsa049780.88675057
63Pyrimidine metabolism_Homo sapiens_hsa002400.88127238
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.86863095
65Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79833074
66Renin-angiotensin system_Homo sapiens_hsa046140.79795087
67Vibrio cholerae infection_Homo sapiens_hsa051100.79683017
68Fatty acid metabolism_Homo sapiens_hsa012120.77526121
69Bladder cancer_Homo sapiens_hsa052190.76001118
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75944096
71Arginine biosynthesis_Homo sapiens_hsa002200.75764958
72Tyrosine metabolism_Homo sapiens_hsa003500.75631703
73RNA degradation_Homo sapiens_hsa030180.75327316
74Carbon metabolism_Homo sapiens_hsa012000.74957347
75Fanconi anemia pathway_Homo sapiens_hsa034600.73440362
76Tight junction_Homo sapiens_hsa045300.71306586
77Biosynthesis of amino acids_Homo sapiens_hsa012300.70159397
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.67087397
79Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.66749517
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.66747200
81Mismatch repair_Homo sapiens_hsa034300.66392561
82Cell cycle_Homo sapiens_hsa041100.65388096
83Bile secretion_Homo sapiens_hsa049760.64461385
84Glycerolipid metabolism_Homo sapiens_hsa005610.64218594
85Lysine degradation_Homo sapiens_hsa003100.63611147
86Purine metabolism_Homo sapiens_hsa002300.63190925
87Huntingtons disease_Homo sapiens_hsa050160.62750217
88Caffeine metabolism_Homo sapiens_hsa002320.61721736
89Pentose phosphate pathway_Homo sapiens_hsa000300.61219217
90Metabolic pathways_Homo sapiens_hsa011000.60438124
91Thyroid cancer_Homo sapiens_hsa052160.60360450
92Nitrogen metabolism_Homo sapiens_hsa009100.57264242
93PPAR signaling pathway_Homo sapiens_hsa033200.57050181
94Nucleotide excision repair_Homo sapiens_hsa034200.56360120
95RNA transport_Homo sapiens_hsa030130.54702105
96Oocyte meiosis_Homo sapiens_hsa041140.54022870
97Basal cell carcinoma_Homo sapiens_hsa052170.53442178
98Base excision repair_Homo sapiens_hsa034100.52578487
99Glucagon signaling pathway_Homo sapiens_hsa049220.51346605
100Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50536345
101Sphingolipid metabolism_Homo sapiens_hsa006000.50401335
102mRNA surveillance pathway_Homo sapiens_hsa030150.50345519
103N-Glycan biosynthesis_Homo sapiens_hsa005100.47847059
104Regulation of autophagy_Homo sapiens_hsa041400.46429397
105Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45502164
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44987967
107Fatty acid biosynthesis_Homo sapiens_hsa000610.43489791
108Spliceosome_Homo sapiens_hsa030400.42626112
109p53 signaling pathway_Homo sapiens_hsa041150.42270610
110Hippo signaling pathway_Homo sapiens_hsa043900.42239056
111Fatty acid elongation_Homo sapiens_hsa000620.39722364
112Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37552522
113ABC transporters_Homo sapiens_hsa020100.37015259
114Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.36722792
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35632077
116Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35040642
117Steroid biosynthesis_Homo sapiens_hsa001000.33232342
118Adherens junction_Homo sapiens_hsa045200.31977793
119Oxidative phosphorylation_Homo sapiens_hsa001900.31332571
120Hedgehog signaling pathway_Homo sapiens_hsa043400.30474425
121Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29588575
122Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.29140743
123Legionellosis_Homo sapiens_hsa051340.28598999
124Lysosome_Homo sapiens_hsa041420.28116311

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