KATNAL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.10197100
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.08628776
3vocalization behavior (GO:0071625)4.69483774
4synaptic vesicle maturation (GO:0016188)4.61769008
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.55135416
6locomotory exploration behavior (GO:0035641)4.54224201
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.49189211
8synaptic vesicle exocytosis (GO:0016079)4.49100066
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.48282465
10glutamate secretion (GO:0014047)4.32028148
11protein localization to synapse (GO:0035418)4.26050687
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.22730449
13regulation of synaptic vesicle exocytosis (GO:2000300)4.20693720
14neuronal action potential propagation (GO:0019227)4.18636027
15regulation of glutamate receptor signaling pathway (GO:1900449)4.05134944
16neuron recognition (GO:0008038)4.00948832
17presynaptic membrane organization (GO:0097090)4.00420221
18axon ensheathment in central nervous system (GO:0032291)3.90165369
19central nervous system myelination (GO:0022010)3.90165369
20glutamate receptor signaling pathway (GO:0007215)3.81195357
21presynaptic membrane assembly (GO:0097105)3.81162952
22axonal fasciculation (GO:0007413)3.74706784
23exploration behavior (GO:0035640)3.73001548
24synaptic transmission, glutamatergic (GO:0035249)3.70117695
25regulation of neuronal synaptic plasticity (GO:0048168)3.68581667
26dendritic spine morphogenesis (GO:0060997)3.67242130
27neurotransmitter secretion (GO:0007269)3.67103887
28transmission of nerve impulse (GO:0019226)3.62619484
29regulation of synaptic vesicle transport (GO:1902803)3.62451509
30neuron-neuron synaptic transmission (GO:0007270)3.59391953
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.56364266
32membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.51880302
33regulation of long-term neuronal synaptic plasticity (GO:0048169)3.50609062
34gamma-aminobutyric acid transport (GO:0015812)3.45600543
35layer formation in cerebral cortex (GO:0021819)3.43500846
36neuronal ion channel clustering (GO:0045161)3.42015127
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.41213277
38gamma-aminobutyric acid signaling pathway (GO:0007214)3.40817477
39retinal cone cell development (GO:0046549)3.39663365
40neurotransmitter transport (GO:0006836)3.33029041
41negative regulation of synaptic transmission, GABAergic (GO:0032229)3.31809134
42L-amino acid import (GO:0043092)3.31726100
43synaptic vesicle docking involved in exocytosis (GO:0016081)3.30819292
44postsynaptic membrane organization (GO:0001941)3.28516807
45regulation of excitatory postsynaptic membrane potential (GO:0060079)3.28218581
46positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.24654846
47dendrite morphogenesis (GO:0048813)3.24126377
48regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.23295388
49long-term memory (GO:0007616)3.21941493
50cellular potassium ion homeostasis (GO:0030007)3.21209113
51adult walking behavior (GO:0007628)3.17372115
52regulation of postsynaptic membrane potential (GO:0060078)3.17363080
53cerebellar Purkinje cell differentiation (GO:0021702)3.16741168
54negative regulation of neurotransmitter transport (GO:0051589)3.13240890
55membrane depolarization during action potential (GO:0086010)3.11304484
56neurotransmitter-gated ion channel clustering (GO:0072578)3.10127419
57calcium ion-dependent exocytosis (GO:0017156)3.08725297
58proline transport (GO:0015824)3.07217150
59regulation of synapse structural plasticity (GO:0051823)3.05044875
60regulation of neurotransmitter secretion (GO:0046928)3.04147784
61regulation of synaptic transmission, glutamatergic (GO:0051966)3.03644315
62synaptic vesicle endocytosis (GO:0048488)3.03414631
63positive regulation of membrane potential (GO:0045838)3.02720007
64membrane hyperpolarization (GO:0060081)3.01746951
65positive regulation of synaptic transmission, GABAergic (GO:0032230)3.01612659
66negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.00801827
67long-term synaptic potentiation (GO:0060291)2.97190138
68cerebellar granule cell differentiation (GO:0021707)2.96891909
69negative regulation of cytosolic calcium ion concentration (GO:0051481)2.96447914
70mating behavior (GO:0007617)2.95930219
71regulation of synaptic plasticity (GO:0048167)2.95758434
72membrane depolarization (GO:0051899)2.95227346
73positive regulation of synapse assembly (GO:0051965)2.94810024
74G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94432583
75positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.93511379
76central nervous system projection neuron axonogenesis (GO:0021952)2.92474446
77synapse assembly (GO:0007416)2.92225578
78response to auditory stimulus (GO:0010996)2.92180512
79regulation of neurotransmitter levels (GO:0001505)2.91529050
80auditory behavior (GO:0031223)2.90787072
81glycine transport (GO:0015816)2.89140252
82regulation of dendritic spine morphogenesis (GO:0061001)2.85701655
83regulation of vesicle fusion (GO:0031338)2.85414458
84regulation of neurotransmitter transport (GO:0051588)2.84729679
85pyrimidine nucleobase catabolic process (GO:0006208)2.83843629
86regulation of respiratory system process (GO:0044065)2.83597102
87startle response (GO:0001964)2.83354447
88learning (GO:0007612)2.82327171
89sodium ion export (GO:0071436)2.81905545
90neuromuscular process controlling posture (GO:0050884)2.80414731
91cell migration in hindbrain (GO:0021535)2.80343593
92cerebral cortex radially oriented cell migration (GO:0021799)2.79422849
93regulation of acrosome reaction (GO:0060046)2.76190872
94dendritic spine organization (GO:0097061)2.74671330
95regulation of respiratory gaseous exchange (GO:0043576)2.73466042
96prepulse inhibition (GO:0060134)2.70640182
97positive regulation of dendritic spine development (GO:0060999)2.70088446
98regulation of synaptic transmission, GABAergic (GO:0032228)2.69150972
99central nervous system neuron axonogenesis (GO:0021955)2.67496189
100synapse organization (GO:0050808)2.66625631
101long-chain fatty acid biosynthetic process (GO:0042759)2.66340022
102regulation of meiosis I (GO:0060631)2.66322821
103synaptic transmission (GO:0007268)2.65429464
104vesicle transport along microtubule (GO:0047496)2.65311587
105activation of protein kinase A activity (GO:0034199)2.65265208
106retinal ganglion cell axon guidance (GO:0031290)2.64271943
107negative regulation of neurotransmitter secretion (GO:0046929)2.64090296
108response to pheromone (GO:0019236)2.63973999
109negative regulation of axon guidance (GO:1902668)2.60415764
110regulation of axon guidance (GO:1902667)2.59604825
111establishment of nucleus localization (GO:0040023)2.52888741
112positive regulation of dendritic spine morphogenesis (GO:0061003)2.51141302
113lymphangiogenesis (GO:0001946)2.50715944
114behavioral response to nicotine (GO:0035095)2.50069292
115regulation of axon extension involved in axon guidance (GO:0048841)2.47261555
116epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.43170444
117nucleus localization (GO:0051647)2.42245608
118negative regulation of axon extension involved in axon guidance (GO:0048843)2.40023854
119negative regulation of hormone biosynthetic process (GO:0032353)2.38428528
120interkinetic nuclear migration (GO:0022027)2.34993152
121positive regulation of meiosis (GO:0045836)2.34588435
122axon extension (GO:0048675)2.32675358
123nucleobase catabolic process (GO:0046113)2.30916304
124positive regulation of gastrulation (GO:2000543)2.30311930
125ganglion development (GO:0061548)2.29427870
126meiotic cell cycle (GO:0051321)2.27496567
127artery development (GO:0060840)2.24312722
128piRNA metabolic process (GO:0034587)2.23952207
129epithelial cilium movement (GO:0003351)2.23256576
130cochlea development (GO:0090102)2.22505851
131cilium morphogenesis (GO:0060271)2.22066444
132mechanosensory behavior (GO:0007638)2.20653143
133positive regulation of cardiac muscle cell differentiation (GO:2000727)2.20366147
134spinal cord development (GO:0021510)2.19254923
135protein polyglutamylation (GO:0018095)2.18570255
136nonmotile primary cilium assembly (GO:0035058)2.18052305
137regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.17378165
138regulation of DNA endoreduplication (GO:0032875)2.16049017
139neuron projection extension (GO:1990138)2.15699260
140retina layer formation (GO:0010842)2.14985533
141urinary tract smooth muscle contraction (GO:0014848)2.12827976
142regulation of synapse assembly (GO:0051963)2.12518224
143behavioral response to ethanol (GO:0048149)2.11969402
144regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.11159500
145appendage development (GO:0048736)2.11041313
146limb development (GO:0060173)2.11041313
147positive regulation of meiotic cell cycle (GO:0051446)2.10844415
148regulation of DNA methylation (GO:0044030)2.10477652
149neuron fate determination (GO:0048664)2.10183877
150inner ear receptor cell development (GO:0060119)2.09862838
151negative chemotaxis (GO:0050919)2.08129938
152regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.07040983
153intraciliary transport (GO:0042073)2.04574256
154cilium movement (GO:0003341)2.03994602
155detection of calcium ion (GO:0005513)2.03666076
156cilium assembly (GO:0042384)2.03202148
157cilium organization (GO:0044782)2.02573308
158microtubule anchoring (GO:0034453)2.02405322
159regulation of calcium ion-dependent exocytosis (GO:0017158)2.02311053
160brain morphogenesis (GO:0048854)2.01646643
161atrial septum morphogenesis (GO:0060413)2.01448893
162olfactory bulb development (GO:0021772)1.98385153
163neuron maturation (GO:0042551)1.97747190
164hindbrain development (GO:0030902)1.96217824

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.57967509
2GBX2_23144817_ChIP-Seq_PC3_Human3.66219122
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.86748314
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.79652810
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.76630070
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.46930012
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.46930012
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.44739547
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.35971089
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.34896499
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.33226722
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31021840
13REST_21632747_ChIP-Seq_MESCs_Mouse2.28633071
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25760494
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.24459967
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.22560121
17TAF15_26573619_Chip-Seq_HEK293_Human2.20405754
18DROSHA_22980978_ChIP-Seq_HELA_Human2.16784602
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.15533817
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.13865008
21SALL1_21062744_ChIP-ChIP_HESCs_Human2.13283351
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.10934321
23BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.10268755
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09081876
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.07272480
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95654153
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94143503
28AR_21572438_ChIP-Seq_LNCaP_Human1.93934935
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89276224
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.87373611
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.85116434
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.80263331
33RARB_27405468_Chip-Seq_BRAIN_Mouse1.79172698
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.78214330
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76545375
36REST_18959480_ChIP-ChIP_MESCs_Mouse1.76203764
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72168326
38SMAD4_21799915_ChIP-Seq_A2780_Human1.71655695
39EWS_26573619_Chip-Seq_HEK293_Human1.68775993
40NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.68760394
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.67950969
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.64685047
43P300_19829295_ChIP-Seq_ESCs_Human1.59432708
44IGF1R_20145208_ChIP-Seq_DFB_Human1.59338677
45EP300_21415370_ChIP-Seq_HL-1_Mouse1.58221251
46TP53_16413492_ChIP-PET_HCT116_Human1.55165539
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52449524
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.52388271
49IKZF1_21737484_ChIP-ChIP_HCT116_Human1.50941976
50* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.49846731
51BMI1_23680149_ChIP-Seq_NPCS_Mouse1.47037079
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.45997446
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.44883876
54POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44432459
55WT1_19549856_ChIP-ChIP_CCG9911_Human1.43933119
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41977959
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41744302
58ZNF274_21170338_ChIP-Seq_K562_Hela1.40268776
59RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.38561010
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.37748081
61RNF2_27304074_Chip-Seq_NSC_Mouse1.36825762
62STAT3_23295773_ChIP-Seq_U87_Human1.34390854
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30553213
64HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.30491726
65PIAS1_25552417_ChIP-Seq_VCAP_Human1.30263640
66* CBP_20019798_ChIP-Seq_JUKART_Human1.29415456
67* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29415456
68TOP2B_26459242_ChIP-Seq_MCF-7_Human1.28575948
69ER_23166858_ChIP-Seq_MCF-7_Human1.28523865
70KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.27752508
71FUS_26573619_Chip-Seq_HEK293_Human1.23679759
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23427007
73BCAT_22108803_ChIP-Seq_LS180_Human1.23267849
74* SOX2_21211035_ChIP-Seq_LN229_Gbm1.22511957
75TCF4_23295773_ChIP-Seq_U87_Human1.22148455
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21996424
77AR_25329375_ChIP-Seq_VCAP_Human1.21380951
78TP53_18474530_ChIP-ChIP_U2OS_Human1.20202588
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19594990
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18701082
81RING1B_27294783_Chip-Seq_ESCs_Mouse1.17338784
82NANOG_18555785_Chip-Seq_ESCs_Mouse1.16860469
83NRF2_20460467_ChIP-Seq_MEFs_Mouse1.16720039
84NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.16720039
85EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16580201
86* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.16030597
87* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15485799
88STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15126355
89TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14932469
90MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.13613561
91SOX9_26525672_Chip-Seq_HEART_Mouse1.12662926
92EZH2_27294783_Chip-Seq_NPCs_Mouse1.11994325
93UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11792556
94CJUN_26792858_Chip-Seq_BT549_Human1.11706879
95SMAD_19615063_ChIP-ChIP_OVARY_Human1.11590090
96VDR_22108803_ChIP-Seq_LS180_Human1.10776339
97PCGF2_27294783_Chip-Seq_NPCs_Mouse1.10004004
98* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09429292
99SUZ12_27294783_Chip-Seq_NPCs_Mouse1.08549612
100TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08000271
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08000271
102PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.07914637
103RUNX2_22187159_ChIP-Seq_PCA_Human1.07609105
104ARNT_22903824_ChIP-Seq_MCF-7_Human1.06798458
105P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06109797
106NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05481482
107EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05442535
108AR_19668381_ChIP-Seq_PC3_Human1.05215802
109* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03511877
110CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03419409
111CMYC_18555785_Chip-Seq_ESCs_Mouse1.02032588
112E2F1_18555785_Chip-Seq_ESCs_Mouse1.01788275
113* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01731141
114PRDM14_20953172_ChIP-Seq_ESCs_Human1.01022620
115MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00979511
116AHR_22903824_ChIP-Seq_MCF-7_Human1.00545877
117RING1B_27294783_Chip-Seq_NPCs_Mouse1.00090514
118YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98972012
119FLI1_27457419_Chip-Seq_LIVER_Mouse0.98151076
120PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97253148
121VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97178405
122P53_22387025_ChIP-Seq_ESCs_Mouse0.97036094
123* KDM2B_26808549_Chip-Seq_REH_Human0.95878420
124RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95199901
125JUN_21703547_ChIP-Seq_K562_Human0.94164763
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.93401153

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.08826176
2MP0003880_abnormal_central_pattern5.02097589
3MP0003635_abnormal_synaptic_transmissio3.58399626
4MP0004270_analgesia3.42581312
5MP0009046_muscle_twitch3.21222875
6MP0005423_abnormal_somatic_nervous3.17176159
7MP0009745_abnormal_behavioral_response3.04003213
8MP0002064_seizures2.94353277
9MP0001968_abnormal_touch/_nociception2.82031374
10MP0002063_abnormal_learning/memory/cond2.78435737
11MP0001486_abnormal_startle_reflex2.73059661
12MP0002272_abnormal_nervous_system2.63681733
13MP0002572_abnormal_emotion/affect_behav2.55576905
14MP0002734_abnormal_mechanical_nocicepti2.51687440
15MP0002736_abnormal_nociception_after2.26871628
16MP0000778_abnormal_nervous_system2.20862045
17MP0006276_abnormal_autonomic_nervous2.16392927
18MP0002735_abnormal_chemical_nociception2.12911893
19MP0001440_abnormal_grooming_behavior2.05934162
20MP0006292_abnormal_olfactory_placode2.03559896
21MP0002067_abnormal_sensory_capabilities1.99847731
22MP0003890_abnormal_embryonic-extraembry1.98863361
23MP0005646_abnormal_pituitary_gland1.92007863
24MP0002733_abnormal_thermal_nociception1.91163246
25MP0005645_abnormal_hypothalamus_physiol1.88039525
26MP0001501_abnormal_sleep_pattern1.85315587
27MP0001529_abnormal_vocalization1.83041976
28MP0001970_abnormal_pain_threshold1.82780363
29MP0002184_abnormal_innervation1.75914062
30MP0008569_lethality_at_weaning1.74828872
31MP0002822_catalepsy1.73892203
32MP0005410_abnormal_fertilization1.73475175
33MP0002557_abnormal_social/conspecific_i1.72031144
34MP0002234_abnormal_pharynx_morphology1.71234794
35MP0004885_abnormal_endolymph1.71229089
36MP0004924_abnormal_behavior1.66653535
37MP0005386_behavior/neurological_phenoty1.66653535
38MP0000955_abnormal_spinal_cord1.62085429
39MP0000920_abnormal_myelination1.61531104
40MP0001984_abnormal_olfaction1.61302416
41MP0003122_maternal_imprinting1.59168528
42MP0004142_abnormal_muscle_tone1.57185353
43MP0003329_amyloid_beta_deposits1.56425987
44MP0008789_abnormal_olfactory_epithelium1.53979700
45MP0004742_abnormal_vestibular_system1.52930939
46MP0002882_abnormal_neuron_morphology1.52103336
47MP0004811_abnormal_neuron_physiology1.51847459
48MP0001905_abnormal_dopamine_level1.50924291
49MP0010368_abnormal_lymphatic_system1.49768357
50MP0004084_abnormal_cardiac_muscle1.48516160
51MP0005503_abnormal_tendon_morphology1.48121307
52MP0003787_abnormal_imprinting1.44538714
53MP0003718_maternal_effect1.40817332
54MP0009780_abnormal_chondrocyte_physiolo1.40670504
55MP0004858_abnormal_nervous_system1.39781134
56MP0002066_abnormal_motor_capabilities/c1.39650642
57MP0001188_hyperpigmentation1.36278838
58MP0001502_abnormal_circadian_rhythm1.35481598
59MP0004145_abnormal_muscle_electrophysio1.32855930
60MP0005187_abnormal_penis_morphology1.29456575
61MP0005551_abnormal_eye_electrophysiolog1.28904882
62MP0002928_abnormal_bile_duct1.26547666
63MP0000534_abnormal_ureter_morphology1.25592147
64MP0003950_abnormal_plasma_membrane1.25152100
65MP0002160_abnormal_reproductive_system1.23523219
66MP0000427_abnormal_hair_cycle1.22715748
67MP0005409_darkened_coat_color1.21316491
68MP0003937_abnormal_limbs/digits/tail_de1.19787630
69MP0003879_abnormal_hair_cell1.19329547
70MP0003633_abnormal_nervous_system1.18233965
71MP0002229_neurodegeneration1.17043772
72MP0008438_abnormal_cutaneous_collagen1.16836996
73MP0002152_abnormal_brain_morphology1.14135753
74MP0010030_abnormal_orbit_morphology1.12903294
75MP0003634_abnormal_glial_cell1.12824285
76MP0002233_abnormal_nose_morphology1.12350976
77MP0005623_abnormal_meninges_morphology1.12316288
78MP0003631_nervous_system_phenotype1.11762739
79MP0003690_abnormal_glial_cell1.10995253
80MP0003755_abnormal_palate_morphology1.08222955
81MP0001963_abnormal_hearing_physiology1.08079574
82MP0001879_abnormal_lymphatic_vessel1.07575392
83MP0000631_abnormal_neuroendocrine_gland1.06273282
84MP0000049_abnormal_middle_ear1.06188718
85MP0009384_cardiac_valve_regurgitation1.05673872
86MP0000751_myopathy1.04429856
87MP0002752_abnormal_somatic_nervous1.03824627
88MP0009250_abnormal_appendicular_skeleto1.03550205
89MP0002909_abnormal_adrenal_gland1.02090365
90MP0008775_abnormal_heart_ventricle1.01051074
91MP0003632_abnormal_nervous_system1.00656657
92MP0003935_abnormal_craniofacial_develop0.99763264
93MP0001485_abnormal_pinna_reflex0.96594622
94MP0005171_absent_coat_pigmentation0.96424965
95MP0002638_abnormal_pupillary_reflex0.96332993
96MP0004133_heterotaxia0.95982719
97MP0001293_anophthalmia0.94745182
98MP0004272_abnormal_basement_membrane0.94084908
99MP0001299_abnormal_eye_distance/0.93660229
100MP0003283_abnormal_digestive_organ0.93475991
101MP0004134_abnormal_chest_morphology0.90446141
102MP0003119_abnormal_digestive_system0.89752329
103MP0002938_white_spotting0.88421580
104MP0001177_atelectasis0.88204469
105MP0000013_abnormal_adipose_tissue0.85579987
106MP0003942_abnormal_urinary_system0.85382679
107MP0002102_abnormal_ear_morphology0.85325546
108MP0000569_abnormal_digit_pigmentation0.85012708
109MP0005499_abnormal_olfactory_system0.84011060
110MP0005394_taste/olfaction_phenotype0.84011060
111MP0005620_abnormal_muscle_contractility0.83295287
112MP0000566_synostosis0.82980657
113MP0003698_abnormal_male_reproductive0.81333923
114MP0004085_abnormal_heartbeat0.81123071
115MP0002069_abnormal_eating/drinking_beha0.81070613
116MP0005253_abnormal_eye_physiology0.75078360
117MP0008872_abnormal_physiological_respon0.74682459
118MP0003137_abnormal_impulse_conducting0.74643489
119MP0000026_abnormal_inner_ear0.73841733
120MP0006072_abnormal_retinal_apoptosis0.73139594
121MP0003861_abnormal_nervous_system0.67857064
122MP0001943_abnormal_respiration0.67695319
123MP0002751_abnormal_autonomic_nervous0.66845352
124MP0001348_abnormal_lacrimal_gland0.66499832
125MP0008877_abnormal_DNA_methylation0.64570379
126MP0001664_abnormal_digestion0.60675527
127MP0004215_abnormal_myocardial_fiber0.59318629
128MP0005535_abnormal_body_temperature0.58475910
129MP0010386_abnormal_urinary_bladder0.58298030
130MP0008874_decreased_physiological_sensi0.55688167
131MP0002090_abnormal_vision0.55498782
132MP0003121_genomic_imprinting0.55313701
133MP0005195_abnormal_posterior_eye0.54141840
134MP0002837_dystrophic_cardiac_calcinosis0.53606626
135MP0003136_yellow_coat_color0.53299479
136MP0002653_abnormal_ependyma_morphology0.53211824

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.32503999
2Myokymia (HP:0002411)5.16893156
3Focal seizures (HP:0007359)4.75172518
4Atonic seizures (HP:0010819)4.11096026
5Epileptic encephalopathy (HP:0200134)4.06878560
6Dynein arm defect of respiratory motile cilia (HP:0012255)4.01647090
7Absent/shortened dynein arms (HP:0200106)4.01647090
8Progressive cerebellar ataxia (HP:0002073)3.94776161
9Febrile seizures (HP:0002373)3.89427692
10Visual hallucinations (HP:0002367)3.73314791
11Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.55052075
12Supranuclear gaze palsy (HP:0000605)3.50757134
13Absence seizures (HP:0002121)3.41807226
14Action tremor (HP:0002345)3.32764115
15Generalized tonic-clonic seizures (HP:0002069)3.22565922
16Degeneration of the lateral corticospinal tracts (HP:0002314)3.22154844
17Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.22154844
18Dialeptic seizures (HP:0011146)3.19595513
19Broad-based gait (HP:0002136)3.19396980
20Ankle clonus (HP:0011448)3.18756852
21Abnormality of the corticospinal tract (HP:0002492)3.17984887
22Gaze-evoked nystagmus (HP:0000640)3.17939550
23Abnormal respiratory motile cilium physiology (HP:0012261)3.17195467
24Abnormal ciliary motility (HP:0012262)3.12300898
25Neurofibrillary tangles (HP:0002185)2.93718676
26Dysmetria (HP:0001310)2.92747918
27Molar tooth sign on MRI (HP:0002419)2.85704833
28Abnormality of midbrain morphology (HP:0002418)2.85704833
29Abnormal respiratory epithelium morphology (HP:0012253)2.82772990
30Abnormal respiratory motile cilium morphology (HP:0005938)2.82772990
31Urinary bladder sphincter dysfunction (HP:0002839)2.77500874
32Spastic gait (HP:0002064)2.77408865
33Dysdiadochokinesis (HP:0002075)2.75231247
34Abnormal eating behavior (HP:0100738)2.74583347
35Impaired vibration sensation in the lower limbs (HP:0002166)2.73232307
36Scanning speech (HP:0002168)2.73230409
37Insidious onset (HP:0003587)2.72906682
38Termporal pattern (HP:0011008)2.72906682
39Hyperventilation (HP:0002883)2.71896486
40Truncal ataxia (HP:0002078)2.68933437
41Peripheral hypomyelination (HP:0007182)2.62255881
42Urinary urgency (HP:0000012)2.57119734
43Limb dystonia (HP:0002451)2.55552191
44Pancreatic fibrosis (HP:0100732)2.55319213
45Pheochromocytoma (HP:0002666)2.53796135
46Papillary thyroid carcinoma (HP:0002895)2.53316216
47Volvulus (HP:0002580)2.50263344
48Supernumerary spleens (HP:0009799)2.50230854
49Depression (HP:0000716)2.45064064
50Anxiety (HP:0000739)2.44937320
51Fair hair (HP:0002286)2.41141721
52Chronic hepatic failure (HP:0100626)2.39864224
53Hemiparesis (HP:0001269)2.39830588
54Progressive inability to walk (HP:0002505)2.39201033
55Cerebral inclusion bodies (HP:0100314)2.37772503
56Genetic anticipation (HP:0003743)2.37554309
57Excessive salivation (HP:0003781)2.37507519
58Drooling (HP:0002307)2.37507519
59Postural instability (HP:0002172)2.37396523
60Absent speech (HP:0001344)2.37123808
61Amblyopia (HP:0000646)2.35882182
62Retinal dysplasia (HP:0007973)2.31413511
63Oligodactyly (hands) (HP:0001180)2.30505971
64Lower limb muscle weakness (HP:0007340)2.28347813
65Gait imbalance (HP:0002141)2.27316516
66Poor eye contact (HP:0000817)2.26919281
67Intention tremor (HP:0002080)2.26466356
68Abnormality of the renal medulla (HP:0100957)2.25549266
69Rhinitis (HP:0012384)2.25122783
70Fetal akinesia sequence (HP:0001989)2.23946294
71Polyphagia (HP:0002591)2.23672613
72Mutism (HP:0002300)2.17834593
73Pancreatic cysts (HP:0001737)2.17388886
74Neuroendocrine neoplasm (HP:0100634)2.16086403
75True hermaphroditism (HP:0010459)2.13999094
76Pachygyria (HP:0001302)2.12854202
77Megalencephaly (HP:0001355)2.11762501
78Agitation (HP:0000713)2.11035999
79Anterior segment dysgenesis (HP:0007700)2.10859008
80Aplasia/Hypoplasia of the tongue (HP:0010295)2.08246833
81Medial flaring of the eyebrow (HP:0010747)2.07802399
82Truncal obesity (HP:0001956)2.06882643
83Abnormality of the renal cortex (HP:0011035)2.05685290
84Optic nerve hypoplasia (HP:0000609)2.04643545
85Abnormality of the ischium (HP:0003174)2.04570955
86Abnormality of the labia minora (HP:0012880)2.02719458
87Abnormal social behavior (HP:0012433)2.02094539
88Impaired social interactions (HP:0000735)2.02094539
89Type II lissencephaly (HP:0007260)1.98365207
90Diplopia (HP:0000651)1.96259571
91Abnormality of binocular vision (HP:0011514)1.96259571
92Epileptiform EEG discharges (HP:0011182)1.96104283
93Impaired smooth pursuit (HP:0007772)1.95609421
94Generalized myoclonic seizures (HP:0002123)1.95250049
95Wrist flexion contracture (HP:0001239)1.94522053
96Specific learning disability (HP:0001328)1.94426943
97Congenital primary aphakia (HP:0007707)1.92065465
98EEG with generalized epileptiform discharges (HP:0011198)1.89715274
99Akinesia (HP:0002304)1.89391825
100Blue irides (HP:0000635)1.88886117
101Sensory axonal neuropathy (HP:0003390)1.88839484
102Aplasia involving bones of the upper limbs (HP:0009823)1.88092150
103Aplasia of the phalanges of the hand (HP:0009802)1.88092150
104Aplasia involving bones of the extremities (HP:0009825)1.88092150
105Impaired vibratory sensation (HP:0002495)1.88017978
106Tubular atrophy (HP:0000092)1.85712490
107Papilledema (HP:0001085)1.84566868
108Lissencephaly (HP:0001339)1.83569551
109Esotropia (HP:0000565)1.82903819
110Protruding tongue (HP:0010808)1.82607432
111Narrow forehead (HP:0000341)1.82198681
112Genital tract atresia (HP:0001827)1.80752272
113Bradykinesia (HP:0002067)1.79939026
114Abnormality of saccadic eye movements (HP:0000570)1.79873691
115Aplasia/Hypoplasia of the tibia (HP:0005772)1.79600772
116Abnormality of ocular smooth pursuit (HP:0000617)1.79268015
117Onion bulb formation (HP:0003383)1.79114557
118Hypsarrhythmia (HP:0002521)1.79097038
119Vaginal atresia (HP:0000148)1.79010218
120Abnormal hair whorl (HP:0010721)1.77937814
121Inability to walk (HP:0002540)1.77800760
122Limited hip movement (HP:0008800)1.77765287
123Postaxial hand polydactyly (HP:0001162)1.76238903
124Overgrowth (HP:0001548)1.76006261
125Nephrogenic diabetes insipidus (HP:0009806)1.75127830
126Abdominal situs inversus (HP:0003363)1.74835397
127Abnormality of abdominal situs (HP:0011620)1.74835397
128Ankle contracture (HP:0006466)1.74762750
129Gait ataxia (HP:0002066)1.72990389
130Heterotopia (HP:0002282)1.72175012
131Nephronophthisis (HP:0000090)1.72051806
132Widely spaced teeth (HP:0000687)1.71895639
133Thyroid carcinoma (HP:0002890)1.70599645
134Alacrima (HP:0000522)1.69088884
135Hypoplastic ischia (HP:0003175)1.68817099
136Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67937299
137Hemiplegia (HP:0002301)1.67630332
138Chorioretinal atrophy (HP:0000533)1.66308385
139Poor coordination (HP:0002370)1.64598628
140Soft skin (HP:0000977)1.63046983
141Thyroid-stimulating hormone excess (HP:0002925)1.61567092
142Bundle branch block (HP:0011710)1.61219916
143Generalized hypopigmentation of hair (HP:0011358)1.60636310
144Short foot (HP:0001773)1.60461475
145Exotropia (HP:0000577)1.59453528
146Cerebellar dysplasia (HP:0007033)1.58407664
147Aplasia/Hypoplasia of the lens (HP:0008063)1.58389699
148Intestinal atresia (HP:0011100)1.57887981
149Abnormality of chromosome segregation (HP:0002916)1.57701296
150Cutaneous finger syndactyly (HP:0010554)1.57684490
151Aplasia/Hypoplasia of the brainstem (HP:0007362)1.56691946
152Hypoplasia of the brainstem (HP:0002365)1.56691946
153Small hand (HP:0200055)1.56121412
154Renal cortical cysts (HP:0000803)1.55369106
155Hip contracture (HP:0003273)1.54867334
156Enlarged penis (HP:0000040)1.54560875
157Micropenis (HP:0000054)1.54335449
158Delayed gross motor development (HP:0002194)1.54049045
159Intellectual disability, moderate (HP:0002342)1.52305166
160Tubulointerstitial abnormality (HP:0001969)1.49762659
161Postaxial foot polydactyly (HP:0001830)1.49732968
162Round face (HP:0000311)1.48813816
163Abnormality of the metopic suture (HP:0005556)1.48625957
164Occipital encephalocele (HP:0002085)1.48401847
165Vascular tortuosity (HP:0004948)1.48323033
166Aqueductal stenosis (HP:0002410)1.48210599
167Pulmonic stenosis (HP:0001642)1.48090281

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.77577641
2CASK3.10561321
3FRK3.05105288
4EPHA43.02099239
5MARK12.99503205
6MAP3K42.67805178
7MAP3K92.63156190
8MAP2K72.46216780
9TNIK2.30678708
10NTRK22.28982263
11MINK12.21677934
12STK392.10303746
13PAK62.08946467
14AKT32.08238287
15PNCK1.93705684
16NTRK11.83271897
17OXSR11.78480504
18CDK191.77628767
19MAPK131.77122250
20PRKD31.76095546
21UHMK11.70648186
22BMPR1B1.60886973
23PRPF4B1.59392609
24MAP3K121.58052171
25CDK51.46017541
26DAPK21.45283571
27EPHB21.45155484
28MAP2K41.39602968
29SGK2231.32692861
30SGK4941.32692861
31TIE11.32023220
32PLK21.31571415
33KSR21.30590039
34FES1.30488796
35ERBB31.26327786
36PHKG11.25639026
37PHKG21.25639026
38WNK11.21708977
39PKN11.20189667
40NEK91.18946564
41CAMK2A1.14929659
42MAP4K21.13887102
43MET1.13183697
44KSR11.12762726
45TRIM281.12475156
46CAMKK11.10517130
47WNK41.08675711
48CSNK1G11.08438436
49GRK51.07187833
50LATS11.05935281
51MAPKAPK51.04528702
52STK31.03857811
53PRKCG1.03801307
54TYRO31.01776578
55CAMK2B0.99790690
56PAK30.99493075
57STK38L0.98816605
58MUSK0.95620407
59SIK20.92888171
60STK380.92729456
61PTK2B0.92707183
62NEK60.92556634
63LMTK20.92259198
64NLK0.91244656
65MARK20.89869167
66CDK180.89669248
67ADRBK20.88576258
68CDK150.87304062
69BCR0.86078824
70CDK140.86023090
71BRSK20.85569883
72CSNK1G20.84874199
73CAMK1G0.84648873
74MAP3K130.83659751
75GRK10.82799692
76MYLK0.81790666
77ARAF0.81205274
78SGK20.80853344
79STK110.80045212
80CAMKK20.79849010
81PDK40.77941809
82PDK30.77941809
83CAMK2D0.77320734
84RIPK40.76370544
85DMPK0.76160435
86CDK11A0.75973737
87FGFR20.75513918
88CAMK10.74230307
89ROCK20.73484891
90PRKCH0.73431375
91WEE10.73157758
92NEK20.72823105
93EPHA30.72785218
94PTK20.72467406
95WNK30.72047211
96MKNK20.71944658
97TNK20.71390366
98SGK10.70577979
99IRAK20.67973900
100DYRK20.67398209
101STK160.67011150
102PRKCE0.65007778
103DYRK1A0.64688034
104INSRR0.64223192
105MAP3K20.64221439
106CCNB10.62320278
107ICK0.62245378
108BRAF0.61352527
109CDK90.60757958
110BMPR20.60450196
111FGR0.60062986
112CAMK2G0.58581043
113NUAK10.56792631
114LATS20.56221066
115SGK30.55627442
116PINK10.54942685
117RET0.54003539
118SIK30.53918107
119STK240.53886887
120DAPK10.53759017
121CSNK1G30.53406771
122MAPK100.52718532
123OBSCN0.52702858
124GRK70.52623870
125ADRBK10.52499020
126PLK30.50662222
127ACVR1B0.50483535
128ROCK10.47186828
129RPS6KA30.46928245
130PDK10.46687232
131PLK10.46271645
132PRKAA10.46198974
133PRKG10.45945579
134PLK40.45221378
135FYN0.45071465
136CSNK1D0.43786080
137PDGFRA0.43655285
138BRD40.43614085
139PDPK10.43468660
140LIMK10.43078928
141TRPM70.41884281
142PDK20.39431657
143CDC42BPA0.39378842
144CSNK1A1L0.36982539
145PRKACA0.36119600

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.83218625
2Synaptic vesicle cycle_Homo sapiens_hsa047213.08703003
3GABAergic synapse_Homo sapiens_hsa047272.63134116
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.62155959
5Glutamatergic synapse_Homo sapiens_hsa047242.55536255
6Olfactory transduction_Homo sapiens_hsa047402.49575624
7Circadian entrainment_Homo sapiens_hsa047132.48584565
8Morphine addiction_Homo sapiens_hsa050322.48084860
9Amphetamine addiction_Homo sapiens_hsa050312.26190528
10Long-term potentiation_Homo sapiens_hsa047202.22820207
11Salivary secretion_Homo sapiens_hsa049702.06863514
12Dopaminergic synapse_Homo sapiens_hsa047282.03416210
13Insulin secretion_Homo sapiens_hsa049111.88154381
14Serotonergic synapse_Homo sapiens_hsa047261.87885297
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.86910873
16Taste transduction_Homo sapiens_hsa047421.86186186
17Cholinergic synapse_Homo sapiens_hsa047251.82058738
18Gastric acid secretion_Homo sapiens_hsa049711.75497664
19Long-term depression_Homo sapiens_hsa047301.70190414
20Cocaine addiction_Homo sapiens_hsa050301.69148815
21Renin secretion_Homo sapiens_hsa049241.64261763
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.62382975
23Collecting duct acid secretion_Homo sapiens_hsa049661.57129125
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56985532
25Axon guidance_Homo sapiens_hsa043601.54613911
26Basal transcription factors_Homo sapiens_hsa030221.54443894
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.50042751
28Calcium signaling pathway_Homo sapiens_hsa040201.49758496
29Oxytocin signaling pathway_Homo sapiens_hsa049211.47195358
30Hippo signaling pathway_Homo sapiens_hsa043901.44578274
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.34211251
32ECM-receptor interaction_Homo sapiens_hsa045121.33739854
33Phototransduction_Homo sapiens_hsa047441.30500722
34Cardiac muscle contraction_Homo sapiens_hsa042601.27025842
35Gap junction_Homo sapiens_hsa045401.25944320
36cAMP signaling pathway_Homo sapiens_hsa040241.25806133
37Butanoate metabolism_Homo sapiens_hsa006501.20136614
38GnRH signaling pathway_Homo sapiens_hsa049121.19797140
39Dorso-ventral axis formation_Homo sapiens_hsa043201.16912525
40Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.16900839
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.15546758
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.14271727
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.14088049
44TGF-beta signaling pathway_Homo sapiens_hsa043501.09509405
45Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05627179
46Fanconi anemia pathway_Homo sapiens_hsa034601.05357649
47ErbB signaling pathway_Homo sapiens_hsa040121.01514995
48Estrogen signaling pathway_Homo sapiens_hsa049151.01280693
49Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99922583
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.98884222
51Type II diabetes mellitus_Homo sapiens_hsa049300.98758586
52Basal cell carcinoma_Homo sapiens_hsa052170.98552381
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95638209
54Vibrio cholerae infection_Homo sapiens_hsa051100.95416334
55Melanogenesis_Homo sapiens_hsa049160.92781174
56Vascular smooth muscle contraction_Homo sapiens_hsa042700.92771248
57Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90739305
58Focal adhesion_Homo sapiens_hsa045100.89083590
59Glioma_Homo sapiens_hsa052140.88442401
60Melanoma_Homo sapiens_hsa052180.87696252
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.87083968
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86838724
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.85861520
64Adherens junction_Homo sapiens_hsa045200.85784771
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.84252937
66Dilated cardiomyopathy_Homo sapiens_hsa054140.83097571
67Pancreatic secretion_Homo sapiens_hsa049720.82218007
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.81294981
69Tight junction_Homo sapiens_hsa045300.79796450
70Choline metabolism in cancer_Homo sapiens_hsa052310.77885128
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77712167
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76817027
73Oocyte meiosis_Homo sapiens_hsa041140.75494960
74Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.74458343
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73947689
76MAPK signaling pathway_Homo sapiens_hsa040100.72110069
77Ether lipid metabolism_Homo sapiens_hsa005650.71157384
78Cell cycle_Homo sapiens_hsa041100.70801406
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70748435
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.70743010
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69590568
82MicroRNAs in cancer_Homo sapiens_hsa052060.67604072
83Thyroid hormone synthesis_Homo sapiens_hsa049180.67418453
84Alzheimers disease_Homo sapiens_hsa050100.67094532
85Alcoholism_Homo sapiens_hsa050340.66472884
86Propanoate metabolism_Homo sapiens_hsa006400.66313744
87Oxidative phosphorylation_Homo sapiens_hsa001900.66195597
88Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65851723
89Ras signaling pathway_Homo sapiens_hsa040140.65646327
90RNA degradation_Homo sapiens_hsa030180.63629755
91Ovarian steroidogenesis_Homo sapiens_hsa049130.61187891
92Lysine degradation_Homo sapiens_hsa003100.60540015
93PI3K-Akt signaling pathway_Homo sapiens_hsa041510.59970706
94Inositol phosphate metabolism_Homo sapiens_hsa005620.59953929
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.57218136
96Wnt signaling pathway_Homo sapiens_hsa043100.55486737
97SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55319545
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.54410505
99Renal cell carcinoma_Homo sapiens_hsa052110.54291377
100Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54148616
101Regulation of autophagy_Homo sapiens_hsa041400.53993584
102Selenocompound metabolism_Homo sapiens_hsa004500.53447103
103Endocytosis_Homo sapiens_hsa041440.52765626
104Steroid biosynthesis_Homo sapiens_hsa001000.52528027
105Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52429305
106ABC transporters_Homo sapiens_hsa020100.50517518
107Glucagon signaling pathway_Homo sapiens_hsa049220.48860677
108FoxO signaling pathway_Homo sapiens_hsa040680.48174003
109Protein export_Homo sapiens_hsa030600.48051614
110Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.47957665
111Proteoglycans in cancer_Homo sapiens_hsa052050.47423752
112Circadian rhythm_Homo sapiens_hsa047100.46396995
113Parkinsons disease_Homo sapiens_hsa050120.45836470
114Rap1 signaling pathway_Homo sapiens_hsa040150.43056634
115Fatty acid biosynthesis_Homo sapiens_hsa000610.42511330
116Huntingtons disease_Homo sapiens_hsa050160.41820852
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.41447973
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40633263
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.37841964
120Hedgehog signaling pathway_Homo sapiens_hsa043400.36847914
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35854192
122Type I diabetes mellitus_Homo sapiens_hsa049400.34810346
123Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33859104
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33058687
125Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32451979
126Fatty acid elongation_Homo sapiens_hsa000620.32084921
127Rheumatoid arthritis_Homo sapiens_hsa053230.31660860
128Prion diseases_Homo sapiens_hsa050200.29025573
129Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27416157

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