IWS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.11511124
2regulation of DNA methylation (GO:0044030)5.89265977
3nuclear pore organization (GO:0006999)5.74621258
4mitotic sister chromatid cohesion (GO:0007064)5.26110294
5positive regulation of histone H3-K4 methylation (GO:0051571)5.05421991
6regulation of meiosis I (GO:0060631)4.85025644
7pore complex assembly (GO:0046931)4.57373254
8meiotic cell cycle (GO:0051321)4.39808676
9pre-miRNA processing (GO:0031054)4.38737407
10mitotic chromosome condensation (GO:0007076)4.34559413
11regulation of histone H3-K9 methylation (GO:0051570)4.28202351
12DNA unwinding involved in DNA replication (GO:0006268)4.27392070
13negative regulation of histone methylation (GO:0031061)4.16983860
14protein localization to kinetochore (GO:0034501)4.13836299
15kinetochore organization (GO:0051383)4.11529997
16DNA strand elongation involved in DNA replication (GO:0006271)4.08923847
17DNA strand elongation (GO:0022616)3.96689901
18piRNA metabolic process (GO:0034587)3.95771888
19* regulation of RNA export from nucleus (GO:0046831)3.94670204
20centriole replication (GO:0007099)3.90556681
21sister chromatid segregation (GO:0000819)3.90128194
22mitotic nuclear envelope disassembly (GO:0007077)3.86226861
23protein localization to chromosome, centromeric region (GO:0071459)3.84766465
24mitotic metaphase plate congression (GO:0007080)3.78820698
25telomere maintenance via semi-conservative replication (GO:0032201)3.76723479
26dosage compensation (GO:0007549)3.73543042
27DNA geometric change (GO:0032392)3.71875124
28DNA replication-dependent nucleosome assembly (GO:0006335)3.71389844
29DNA replication-dependent nucleosome organization (GO:0034723)3.71389844
30DNA duplex unwinding (GO:0032508)3.71297492
31membrane disassembly (GO:0030397)3.68849654
32nuclear envelope disassembly (GO:0051081)3.68849654
33regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.67666125
34positive regulation of histone methylation (GO:0031062)3.64913813
35establishment of integrated proviral latency (GO:0075713)3.64714140
36regulation of DNA endoreduplication (GO:0032875)3.58265747
37regulation of spindle organization (GO:0090224)3.55528722
38regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.51830361
39regulation of spindle checkpoint (GO:0090231)3.51393119
40positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.51361865
41positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.51361865
42positive regulation of mitotic sister chromatid separation (GO:1901970)3.51361865
43mitotic G2/M transition checkpoint (GO:0044818)3.51091265
44telomere maintenance via recombination (GO:0000722)3.50579942
45metaphase plate congression (GO:0051310)3.50293744
46regulation of mitotic spindle checkpoint (GO:1903504)3.49793907
47regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.49793907
48mitotic sister chromatid segregation (GO:0000070)3.45557228
49monoubiquitinated protein deubiquitination (GO:0035520)3.45191961
50double-strand break repair via nonhomologous end joining (GO:0006303)3.43479327
51non-recombinational repair (GO:0000726)3.43479327
52mitotic recombination (GO:0006312)3.43339744
53regulation of sister chromatid cohesion (GO:0007063)3.42772615
54negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.42144662
55regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.41559615
56regulation of mitotic spindle organization (GO:0060236)3.33856882
57positive regulation of chromosome segregation (GO:0051984)3.27762446
58translesion synthesis (GO:0019985)3.25917470
59kinetochore assembly (GO:0051382)3.24253212
60negative regulation of RNA splicing (GO:0033119)3.23208214
61chromatin assembly or disassembly (GO:0006333)3.22774509
62histone mRNA catabolic process (GO:0071044)3.22405649
63regulation of centriole replication (GO:0046599)3.21077503
64regulation of histone H3-K4 methylation (GO:0051569)3.20983016
65negative regulation of mRNA processing (GO:0050686)3.20015484
66chromatin assembly (GO:0031497)3.19976367
67sister chromatid cohesion (GO:0007062)3.19650805
68synapsis (GO:0007129)3.18944986
69DNA replication-independent nucleosome organization (GO:0034724)3.18687272
70DNA replication-independent nucleosome assembly (GO:0006336)3.18687272
71RNA stabilization (GO:0043489)3.18309494
72mRNA stabilization (GO:0048255)3.18309494
73alternative mRNA splicing, via spliceosome (GO:0000380)3.18107691
74nucleotide-excision repair, DNA gap filling (GO:0006297)3.17891423
75meiotic chromosome segregation (GO:0045132)3.15505937
76DNA topological change (GO:0006265)3.12492533
77DNA conformation change (GO:0071103)3.11523088
78negative regulation of DNA-dependent DNA replication (GO:2000104)3.11143465
79histone H2A monoubiquitination (GO:0035518)3.10968207
80telomere maintenance via telomere lengthening (GO:0010833)3.10443568
81ATP-dependent chromatin remodeling (GO:0043044)3.08165841
82protein localization to chromosome (GO:0034502)3.06690551
83retinal cone cell development (GO:0046549)3.05553045
84DNA methylation involved in gamete generation (GO:0043046)3.04239981
85postreplication repair (GO:0006301)3.03865162
86regulation of helicase activity (GO:0051095)3.03490304
87chromatin remodeling at centromere (GO:0031055)3.03059969
88histone H2B ubiquitination (GO:0033523)3.02451015
89regulation of centrosome cycle (GO:0046605)3.01973991
90regulation of chromosome segregation (GO:0051983)3.01535506
91spindle checkpoint (GO:0031577)3.01152771
92telomere maintenance via telomerase (GO:0007004)3.00950883
93negative regulation of DNA repair (GO:0045738)2.99612931
94negative regulation of mitotic sister chromatid separation (GO:2000816)2.98938479
95negative regulation of sister chromatid segregation (GO:0033046)2.98938479
96negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.98938479
97negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.98938479
98negative regulation of mitotic sister chromatid segregation (GO:0033048)2.98938479
99attachment of spindle microtubules to kinetochore (GO:0008608)2.98467301
100negative regulation of mRNA metabolic process (GO:1903312)2.97137824
101folic acid-containing compound biosynthetic process (GO:0009396)2.95737075
102mRNA splice site selection (GO:0006376)2.95632751
103paraxial mesoderm development (GO:0048339)2.95049818
104CENP-A containing nucleosome assembly (GO:0034080)2.94981617
105establishment of chromosome localization (GO:0051303)2.94134739
106regulation of mitotic metaphase/anaphase transition (GO:0030071)2.93421174
107gene silencing by RNA (GO:0031047)2.92106583
108IMP biosynthetic process (GO:0006188)2.91700439
109female gamete generation (GO:0007292)2.91699897
110spliceosomal tri-snRNP complex assembly (GO:0000244)2.91578306
111histone H3-K9 methylation (GO:0051567)2.90987738
112* regulation of nucleobase-containing compound transport (GO:0032239)2.90322576
113formation of translation preinitiation complex (GO:0001731)2.89671052
114nuclear envelope organization (GO:0006998)2.89233454
115regulation of telomere maintenance via telomerase (GO:0032210)2.88655763
116regulation of posttranscriptional gene silencing (GO:0060147)2.88029282
117regulation of gene silencing by miRNA (GO:0060964)2.88029282
118regulation of gene silencing by RNA (GO:0060966)2.88029282
119* mRNA transport (GO:0051028)2.87950233
120DNA replication initiation (GO:0006270)2.87795035
121spindle assembly checkpoint (GO:0071173)2.86701389
122heterochromatin organization (GO:0070828)2.86321054
123histone exchange (GO:0043486)2.86285365
124regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.85826371
125chromosome condensation (GO:0030261)2.84944067
126DNA replication checkpoint (GO:0000076)2.84818847
127chromosome segregation (GO:0007059)2.83580110
128mitotic spindle checkpoint (GO:0071174)2.81142688
129regulation of mitotic sister chromatid separation (GO:0010965)2.79539765
130regulation of mitotic sister chromatid segregation (GO:0033047)2.79539765
131regulation of sister chromatid segregation (GO:0033045)2.79539765
132negative regulation of histone modification (GO:0031057)2.79496278
133DNA packaging (GO:0006323)2.77340378
134negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.77201264
135ribosome assembly (GO:0042255)2.77126683
136mitotic spindle assembly checkpoint (GO:0007094)2.76613040
137negative regulation of chromosome segregation (GO:0051985)2.76314636
138regulation of mRNA stability (GO:0043488)2.75463801

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.21136655
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.65847922
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.04335042
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.51791801
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.43916196
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.41419600
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.38419500
8EZH2_22144423_ChIP-Seq_EOC_Human3.27277676
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.21714698
10* MYC_18555785_ChIP-Seq_MESCs_Mouse2.95724505
11TP63_19390658_ChIP-ChIP_HaCaT_Human2.66636720
12* E2F1_21310950_ChIP-Seq_MCF-7_Human2.61987916
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.44800223
14AR_21909140_ChIP-Seq_LNCAP_Human2.39215935
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.31103217
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.30575735
17HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.29338462
18MYC_22102868_ChIP-Seq_BL_Human2.28645441
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.27731597
20NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.05347704
21MYC_19030024_ChIP-ChIP_MESCs_Mouse2.04588512
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.02947909
23E2F7_22180533_ChIP-Seq_HELA_Human10.9523083
24MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95454524
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.79172475
26RBPJ_22232070_ChIP-Seq_NCS_Mouse1.78181840
27* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.75355178
28MYCN_18555785_ChIP-Seq_MESCs_Mouse1.71270155
29THAP11_20581084_ChIP-Seq_MESCs_Mouse1.70841118
30CIITA_25753668_ChIP-Seq_RAJI_Human1.69861559
31BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.68201424
32HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.63179796
33FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.62157648
34SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.60857441
35PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59056729
36* DCP1A_22483619_ChIP-Seq_HELA_Human1.54859943
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53724806
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.52155348
39GATA1_26923725_Chip-Seq_HPCs_Mouse1.47482896
40EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.45668463
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.45012866
42ELK1_19687146_ChIP-ChIP_HELA_Human1.43936752
43XRN2_22483619_ChIP-Seq_HELA_Human1.42948524
44* VDR_23849224_ChIP-Seq_CD4+_Human1.39545623
45KDM5A_27292631_Chip-Seq_BREAST_Human1.39165135
46STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.35643884
47RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35270337
48SOX2_18555785_ChIP-Seq_MESCs_Mouse1.34508621
49HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.32993544
50* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32062669
51* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.31250598
52CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.25937988
53FOXP3_21729870_ChIP-Seq_TREG_Human1.25911916
54* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.23879758
55PKCTHETA_26484144_Chip-Seq_BREAST_Human1.22926298
56SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.22842027
57EWS_26573619_Chip-Seq_HEK293_Human1.20087891
58YY1_21170310_ChIP-Seq_MESCs_Mouse1.19965529
59* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.19273710
60TTF2_22483619_ChIP-Seq_HELA_Human1.19214043
61SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.17720444
62EST1_17652178_ChIP-ChIP_JURKAT_Human1.17009147
63NANOG_18555785_ChIP-Seq_MESCs_Mouse1.16235163
64FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.13326399
65* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12766629
66WT1_19549856_ChIP-ChIP_CCG9911_Human1.11995104
67ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.11821851
68ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07670726
69KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.05077411
70KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.05077411
71KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.05077411
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.04473709
73TCF3_18692474_ChIP-Seq_MESCs_Mouse1.03197739
74NANOG_21062744_ChIP-ChIP_HESCs_Human1.02424798
75ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01126556
76TCF7_22412390_ChIP-Seq_EML_Mouse1.00642857
77ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.00579320
78CREB1_15753290_ChIP-ChIP_HEK293T_Human1.00319643
79NANOG_16153702_ChIP-ChIP_HESCs_Human0.99453967
80CHD1_26751641_Chip-Seq_LNCaP_Human0.98773783
81HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98481632
82NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.98424843
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97997613
84NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.97605084
85NOTCH1_21737748_ChIP-Seq_TLL_Human0.96772952
86TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96241983
87* MYB_26560356_Chip-Seq_TH1_Human0.96146740
88FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.95383534
89PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.95310611
90* MYC_18940864_ChIP-ChIP_HL60_Human0.95253155
91SOX17_20123909_ChIP-Seq_XEN_Mouse0.94556403
92SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94534078
93KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92637860
94E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.91655420
95STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.90800020
96KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.90685764
97* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.89771535
98POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88491556
99TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.88137454
100IRF1_19129219_ChIP-ChIP_H3396_Human0.87749559
101DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87713778
102ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.86275903
103FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.85082231
104* ETS1_20019798_ChIP-Seq_JURKAT_Human0.84873966
105UTX_26944678_Chip-Seq_JUKART_Human0.84226548
106GABP_19822575_ChIP-Seq_HepG2_Human0.84019571
107MYB_26560356_Chip-Seq_TH2_Human0.83784621
108KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.82894320
109STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.82126790
110POU5F1_16153702_ChIP-ChIP_HESCs_Human0.81659305
111* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.81639846
112SOX2_16153702_ChIP-ChIP_HESCs_Human0.81522686
113TFEB_21752829_ChIP-Seq_HELA_Human0.81341567
114KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.81283923
115POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.80922485
116CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.80864710
117POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.80449686
118E2F1_18555785_ChIP-Seq_MESCs_Mouse0.80406034
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.80107434
120TCF3_18692474_ChIP-Seq_MEFs_Mouse0.80093373
121STAT6_21828071_ChIP-Seq_BEAS2B_Human0.79434629
122CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.79002833
123VDR_21846776_ChIP-Seq_THP-1_Human0.77046830
124* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.76948799
125ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.75487068
126ELF1_17652178_ChIP-ChIP_JURKAT_Human0.74457184
127TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.71236517
128TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.69821822
129NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.66525762
130GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.66135027

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003718_maternal_effect4.23506944
2MP0006292_abnormal_olfactory_placode4.14572068
3MP0010094_abnormal_chromosome_stability3.64045242
4MP0008057_abnormal_DNA_replication3.62869708
5MP0003111_abnormal_nucleus_morphology3.61110192
6MP0003693_abnormal_embryo_hatching3.56705328
7MP0003077_abnormal_cell_cycle3.15242925
8MP0004957_abnormal_blastocyst_morpholog2.76455357
9MP0005499_abnormal_olfactory_system2.62949132
10MP0005394_taste/olfaction_phenotype2.62949132
11MP0008877_abnormal_DNA_methylation2.60767678
12MP0010352_gastrointestinal_tract_polyps2.57830248
13MP0008058_abnormal_DNA_repair2.55477834
14MP0008007_abnormal_cellular_replicative2.46999974
15MP0010307_abnormal_tumor_latency2.43983192
16MP0005076_abnormal_cell_differentiation2.41492942
17MP0000569_abnormal_digit_pigmentation2.37885271
18MP0003123_paternal_imprinting2.21103903
19MP0001730_embryonic_growth_arrest2.09386574
20MP0000350_abnormal_cell_proliferation2.08630721
21MP0003890_abnormal_embryonic-extraembry2.07653155
22MP0003121_genomic_imprinting2.06454961
23MP0001672_abnormal_embryogenesis/_devel1.89685985
24MP0005380_embryogenesis_phenotype1.89685985
25MP0004197_abnormal_fetal_growth/weight/1.85055395
26MP0002396_abnormal_hematopoietic_system1.82412670
27MP0004808_abnormal_hematopoietic_stem1.76571436
28MP0003984_embryonic_growth_retardation1.76026576
29MP0002088_abnormal_embryonic_growth/wei1.75570713
30MP0002084_abnormal_developmental_patter1.73712475
31MP0003787_abnormal_imprinting1.68312246
32MP0005395_other_phenotype1.67747487
33MP0000537_abnormal_urethra_morphology1.65564284
34MP0009053_abnormal_anal_canal1.64866543
35MP0002086_abnormal_extraembryonic_tissu1.63594644
36MP0001697_abnormal_embryo_size1.62922416
37MP0002085_abnormal_embryonic_tissue1.62309022
38MP0008932_abnormal_embryonic_tissue1.59002866
39MP0003941_abnormal_skin_development1.57752111
40MP0003567_abnormal_fetal_cardiomyocyte1.50870868
41MP0003705_abnormal_hypodermis_morpholog1.49641042
42MP0001293_anophthalmia1.49080305
43MP0003937_abnormal_limbs/digits/tail_de1.36728765
44MP0003699_abnormal_female_reproductive1.35476999
45MP0002080_prenatal_lethality1.35274968
46MP0010030_abnormal_orbit_morphology1.34870373
47MP0009703_decreased_birth_body1.29604163
48MP0009672_abnormal_birth_weight1.29511069
49MP0003763_abnormal_thymus_physiology1.28668269
50MP0000703_abnormal_thymus_morphology1.21473508
51MP0003119_abnormal_digestive_system1.19544637
52MP0003786_premature_aging1.19159441
53MP0000490_abnormal_crypts_of1.16312135
54MP0010234_abnormal_vibrissa_follicle1.15487347
55MP0003935_abnormal_craniofacial_develop1.11584733
56MP0002166_altered_tumor_susceptibility1.11326592
57MP0000313_abnormal_cell_death1.11191149
58MP0000428_abnormal_craniofacial_morphol1.10824327
59MP0009697_abnormal_copulation1.10696420
60MP0002092_abnormal_eye_morphology1.10513009
61MP0000566_synostosis1.10315901
62MP0000432_abnormal_head_morphology1.09862051
63MP0000733_abnormal_muscle_development1.08558656
64MP0002697_abnormal_eye_size1.07725545
65MP0002009_preneoplasia1.07481076
66MP0002210_abnormal_sex_determination1.07461859
67MP0001915_intracranial_hemorrhage1.06262268
68MP0001286_abnormal_eye_development1.06110369
69MP0002161_abnormal_fertility/fecundity0.99956998
70MP0002019_abnormal_tumor_incidence0.98954416
71MP0003300_gastrointestinal_ulcer0.98011540
72MP0005367_renal/urinary_system_phenotyp0.96088847
73MP0000516_abnormal_urinary_system0.96088847
74MP0002269_muscular_atrophy0.95631730
75MP0001849_ear_inflammation0.94750309
76MP0003115_abnormal_respiratory_system0.94701005
77MP0002925_abnormal_cardiovascular_devel0.93217485
78MP0006054_spinal_hemorrhage0.92611402
79MP0003186_abnormal_redox_activity0.92452908
80MP0005451_abnormal_body_composition0.92261162
81MP0002006_tumorigenesis0.91750021
82MP0001145_abnormal_male_reproductive0.90535311
83MP0002138_abnormal_hepatobiliary_system0.90517165
84MP0004264_abnormal_extraembryonic_tissu0.88724448
85MP0002398_abnormal_bone_marrow0.88709034
86MP0005501_abnormal_skin_physiology0.88678434
87MP0004233_abnormal_muscle_weight0.88563670
88MP0002938_white_spotting0.87502934
89MP0003755_abnormal_palate_morphology0.87210510
90MP0002111_abnormal_tail_morphology0.86490699
91MP0001929_abnormal_gametogenesis0.84822164
92MP0000762_abnormal_tongue_morphology0.82463154
93MP0009278_abnormal_bone_marrow0.81864571
94MP0010368_abnormal_lymphatic_system0.81236005
95MP0000653_abnormal_sex_gland0.81110689
96MP0002234_abnormal_pharynx_morphology0.79101764
97MP0001119_abnormal_female_reproductive0.78834771
98MP0002139_abnormal_hepatobiliary_system0.78236199
99MP0000383_abnormal_hair_follicle0.77727648
100MP0002163_abnormal_gland_morphology0.77469584
101MP0006035_abnormal_mitochondrial_morpho0.76794064
102MP0002722_abnormal_immune_system0.76412191
103MP0003136_yellow_coat_color0.76101140
104MP0009379_abnormal_foot_pigmentation0.76018242
105MP0000358_abnormal_cell_content/0.75863618
106MP0003861_abnormal_nervous_system0.75304339
107MP0005187_abnormal_penis_morphology0.75009635
108MP0005384_cellular_phenotype0.74980759
109MP0000049_abnormal_middle_ear0.74842776
110MP0010678_abnormal_skin_adnexa0.73777258
111MP0005023_abnormal_wound_healing0.73000699
112MP0002796_impaired_skin_barrier0.72995067
113MP0003385_abnormal_body_wall0.72198171
114MP0003122_maternal_imprinting0.72152957
115MP0000631_abnormal_neuroendocrine_gland0.71052861
116MP0003698_abnormal_male_reproductive0.70826532
117MP0002098_abnormal_vibrissa_morphology0.70394917
118MP0003566_abnormal_cell_adhesion0.69700836
119MP0005248_abnormal_Harderian_gland0.69480395
120MP0000266_abnormal_heart_morphology0.69274230
121MP0002160_abnormal_reproductive_system0.69249130
122MP0005621_abnormal_cell_physiology0.66439566
123MP0000427_abnormal_hair_cycle0.66297829
124MP0002116_abnormal_craniofacial_bone0.65944236
125MP0004185_abnormal_adipocyte_glucose0.65307803
126MP0002653_abnormal_ependyma_morphology0.65170146
127MP0002114_abnormal_axial_skeleton0.65087783
128MP0000689_abnormal_spleen_morphology0.64706142
129MP0002233_abnormal_nose_morphology0.64326992
130MP0008789_abnormal_olfactory_epithelium0.63867953
131MP0003943_abnormal_hepatobiliary_system0.63429313
132MP0003221_abnormal_cardiomyocyte_apopto0.63175820
133MP0005408_hypopigmentation0.63088352
134MP0002932_abnormal_joint_morphology0.62843804
135MP0006072_abnormal_retinal_apoptosis0.56494245
136MP0001299_abnormal_eye_distance/0.55792602
137MP0003806_abnormal_nucleotide_metabolis0.55782241
138MP0005391_vision/eye_phenotype0.55591905

Predicted human phenotypes

RankGene SetZ-score
1Septo-optic dysplasia (HP:0100842)3.98334871
2Volvulus (HP:0002580)3.71423025
3Abnormality of the fingertips (HP:0001211)3.40589713
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.21504165
5Short 4th metacarpal (HP:0010044)3.21504165
6Abnormal lung lobation (HP:0002101)3.15033172
7Supernumerary spleens (HP:0009799)3.12401154
8Chromsome breakage (HP:0040012)3.11733928
9Abnormality of abdominal situs (HP:0011620)3.09097483
10Abdominal situs inversus (HP:0003363)3.09097483
11Chromosomal breakage induced by crosslinking agents (HP:0003221)2.95585089
12Embryonal renal neoplasm (HP:0011794)2.93758904
13Increased nuchal translucency (HP:0010880)2.84315339
14Absent septum pellucidum (HP:0001331)2.82655231
15Ectopic kidney (HP:0000086)2.80090247
16Long eyelashes (HP:0000527)2.74153613
17Gonadotropin excess (HP:0000837)2.71675457
18Medulloblastoma (HP:0002885)2.70386443
19Birth length less than 3rd percentile (HP:0003561)2.68638401
20Abnormality of the septum pellucidum (HP:0007375)2.67087597
21Osteomalacia (HP:0002749)2.64535733
22Ependymoma (HP:0002888)2.62454413
23Horseshoe kidney (HP:0000085)2.58491927
24Impulsivity (HP:0100710)2.58226619
25Colon cancer (HP:0003003)2.57058395
26Abnormality of chromosome stability (HP:0003220)2.54446948
27Microglossia (HP:0000171)2.51344528
28Prominent nose (HP:0000448)2.50638934
29Median cleft lip (HP:0000161)2.45140119
30Premature ovarian failure (HP:0008209)2.42651715
31Multiple enchondromatosis (HP:0005701)2.42157435
32Capillary hemangiomas (HP:0005306)2.41550795
33Bifid tongue (HP:0010297)2.40113634
34Selective tooth agenesis (HP:0001592)2.37792061
35Biliary tract neoplasm (HP:0100574)2.36848635
36Deviation of the thumb (HP:0009603)2.34287711
37Proximal placement of thumb (HP:0009623)2.33357131
38Deep palmar crease (HP:0006191)2.30482137
39Hypoplastic labia majora (HP:0000059)2.26333512
40Anal stenosis (HP:0002025)2.24626399
41Abnormality of the astrocytes (HP:0100707)2.24522618
42Astrocytoma (HP:0009592)2.24522618
43Renovascular hypertension (HP:0100817)2.24015797
44Glioma (HP:0009733)2.20566499
45Rhabdomyosarcoma (HP:0002859)2.20482962
46Male infertility (HP:0003251)2.19006162
47Meckel diverticulum (HP:0002245)2.18505760
48Stenosis of the external auditory canal (HP:0000402)2.18367396
49Abnormality of the labia minora (HP:0012880)2.17839188
50Abnormality of the 4th metacarpal (HP:0010012)2.17805791
51Deep philtrum (HP:0002002)2.17008897
52Skull defect (HP:0001362)2.16855275
53Microvesicular hepatic steatosis (HP:0001414)2.16797531
54Papillary thyroid carcinoma (HP:0002895)2.15544463
55Heterotopia (HP:0002282)2.15404183
56Patellar aplasia (HP:0006443)2.13559761
57Progressive external ophthalmoplegia (HP:0000590)2.13217849
58Renal duplication (HP:0000075)2.12846818
59Neoplasm of the oral cavity (HP:0100649)2.11039216
60Urethral obstruction (HP:0000796)2.10496456
61Duplication of thumb phalanx (HP:0009942)2.10466859
62Aplasia/Hypoplasia of the uvula (HP:0010293)2.09844446
63Hyperacusis (HP:0010780)2.09655059
64Abnormal number of incisors (HP:0011064)2.08035253
65Cortical dysplasia (HP:0002539)2.07388169
66Abnormal gallbladder physiology (HP:0012438)2.07142134
67Cholecystitis (HP:0001082)2.07142134
68Aplasia/Hypoplasia of the patella (HP:0006498)2.06333286
69Malignant gastrointestinal tract tumors (HP:0006749)2.05930123
70Gastrointestinal carcinoma (HP:0002672)2.05930123
71Hypophosphatemic rickets (HP:0004912)2.05782101
72Abnormality of the labia majora (HP:0012881)2.05619741
73Abnormality of the ileum (HP:0001549)2.05374564
74Abnormal hair whorl (HP:0010721)2.04071488
75Thyroid carcinoma (HP:0002890)2.04010814
76Abnormality of the carotid arteries (HP:0005344)2.03104305
77Aplasia/Hypoplasia of the sternum (HP:0006714)2.03095516
78Poikiloderma (HP:0001029)2.02599174
79Abnormality of the preputium (HP:0100587)2.02217215
80High pitched voice (HP:0001620)2.01402328
81Cleft eyelid (HP:0000625)2.00957865
82Subacute progressive viral hepatitis (HP:0006572)2.00770620
83Trigonocephaly (HP:0000243)2.00495442
84Facial hemangioma (HP:0000329)1.99860924
85Myelodysplasia (HP:0002863)1.98787550
86Sandal gap (HP:0001852)1.98463465
87Syringomyelia (HP:0003396)1.96896593
88Spinal cord lesions (HP:0100561)1.96896593
89Choanal atresia (HP:0000453)1.96875885
90Absent radius (HP:0003974)1.95996874
91Triphalangeal thumb (HP:0001199)1.95315936
92Pelvic girdle muscle weakness (HP:0003749)1.94054319
93Abnormality of DNA repair (HP:0003254)1.93400606
94Oligodactyly (HP:0012165)1.93068684
95Maternal diabetes (HP:0009800)1.92907930
96Cutis marmorata (HP:0000965)1.91641530
97Neoplasm of striated muscle (HP:0009728)1.90933774
98Obsessive-compulsive behavior (HP:0000722)1.90608531
99Hypoplastic pelvis (HP:0008839)1.90141108
100Broad alveolar ridges (HP:0000187)1.90015467
101Short tibia (HP:0005736)1.89036671
102Myelomeningocele (HP:0002475)1.88230597
103Short thumb (HP:0009778)1.87940936
104Supernumerary ribs (HP:0005815)1.86572231
105Pseudobulbar signs (HP:0002200)1.86297961
106T lymphocytopenia (HP:0005403)1.86148009
107Reticulocytopenia (HP:0001896)1.85015774
108Lip pit (HP:0100267)1.84629337
109Facial cleft (HP:0002006)1.82649296
110Atresia of the external auditory canal (HP:0000413)1.82453133
111Intrahepatic cholestasis (HP:0001406)1.82448710
112Basal cell carcinoma (HP:0002671)1.82127779
113Absent forearm bone (HP:0003953)1.82038286
114Aplasia involving forearm bones (HP:0009822)1.82038286
115Truncal obesity (HP:0001956)1.81368935
116Acute myeloid leukemia (HP:0004808)1.81338056
117Cafe-au-lait spot (HP:0000957)1.80204224
118Small intestinal stenosis (HP:0012848)1.79987736
119Duodenal stenosis (HP:0100867)1.79987736
120Low anterior hairline (HP:0000294)1.79435595
121Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.79240798
122Entropion (HP:0000621)1.78262296
123Partial duplication of thumb phalanx (HP:0009944)1.76977207
124Wide intermamillary distance (HP:0006610)1.76798221
125Absent frontal sinuses (HP:0002688)1.76785182
126Broad thumb (HP:0011304)1.73506466
127Oligodactyly (hands) (HP:0001180)1.73216950
128Breast hypoplasia (HP:0003187)1.73164245
129Tracheoesophageal fistula (HP:0002575)1.71307194
130Supernumerary bones of the axial skeleton (HP:0009144)1.70869891
131Stillbirth (HP:0003826)1.69236921
132Elfin facies (HP:0004428)1.68557497
133Carpal bone hypoplasia (HP:0001498)1.67687935
134Neoplasm of the pancreas (HP:0002894)1.66764035
135Skin tags (HP:0010609)1.66656884
136Tubulointerstitial nephritis (HP:0001970)1.66318545
137Overriding aorta (HP:0002623)1.65867483
138Rib fusion (HP:0000902)1.65583341
139Hepatoblastoma (HP:0002884)1.64405999
140Absent thumb (HP:0009777)1.64262848
141Embryonal neoplasm (HP:0002898)1.64031369
142Dislocated radial head (HP:0003083)1.63640951
143Sloping forehead (HP:0000340)1.63358349
144Abnormal biliary tract morphology (HP:0012440)1.63035911
145Intestinal atresia (HP:0011100)1.62735160
146Nephroblastoma (Wilms tumor) (HP:0002667)1.62423718
147Overlapping toe (HP:0001845)1.62385418
148Abnormality of T cell number (HP:0011839)1.62106186
149Transitional cell carcinoma of the bladder (HP:0006740)1.61556840
150Abnormality of the diencephalon (HP:0010662)1.61472498
151Sensory axonal neuropathy (HP:0003390)1.61328238
152Narrow palate (HP:0000189)1.61268342
153Posterior subcapsular cataract (HP:0007787)1.61015915
154Abnormality of the duodenum (HP:0002246)1.60608626

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.63241353
2CDK124.24851824
3MAP3K92.79362012
4SRPK12.75760962
5LATS12.69080970
6NEK22.67527114
7MKNK12.44358297
8EIF2AK32.44292659
9PBK2.28683252
10BRD42.16384054
11TRIM282.10934077
12TTK2.06376816
13MKNK22.03441358
14WEE11.96124293
15STK31.95128868
16MAP3K101.88134220
17ARAF1.87859452
18ATR1.79784815
19BRAF1.75870736
20PASK1.66003157
21ACVR1B1.64384257
22CHEK21.64342120
23ZAK1.63396359
24TLK11.60840800
25TNIK1.60247471
26PLK31.59091453
27STK101.55526947
28CDK191.55406039
29CHEK11.55224708
30PLK11.53721568
31CDK61.53421506
32AURKB1.53302971
33ERBB31.53037220
34PLK41.52650858
35NUAK11.48864361
36SCYL21.48179831
37EEF2K1.44541927
38BUB11.43242703
39MAP3K131.42267461
40CDK41.40495962
41CDK71.40409814
42STK41.38299806
43ATM1.36679218
44MST41.31092453
45RPS6KB21.24679310
46FGFR31.24190863
47DYRK31.21901403
48NEK61.17347317
49BRSK21.17295742
50RPS6KA41.15910691
51MTOR1.15212344
52FRK1.14661383
53KSR11.11575607
54BMPR1B1.09215854
55CDK21.09005066
56BRSK11.08759044
57RAF11.08231639
58PNCK1.07789487
59FGFR21.06697579
60TGFBR11.06036791
61MELK1.04399193
62ALK1.04033794
63STK161.00736605
64MAP3K40.99643414
65CAMK1D0.97011021
66PKN20.95797610
67MAP3K80.95756743
68TYRO30.95472865
69TSSK60.94413375
70CDK90.89654073
71CDK10.89068105
72PDGFRA0.86788659
73EPHA20.86715889
74PDK20.86500793
75PIM10.85475887
76FGFR10.85207805
77MAP4K10.81765922
78PLK20.81636640
79MET0.81430970
80STK38L0.81062290
81ERBB40.80597975
82EIF2AK10.78657429
83CDK80.78081301
84FGFR40.76391491
85TAF10.76094477
86MOS0.74203806
87CHUK0.74107568
88PDGFRB0.73548908
89BCR0.71581617
90PRKCI0.71508063
91CLK10.69644803
92CAMK1G0.69436474
93ITK0.69339691
94PTK60.67838613
95WNK10.67750310
96MARK30.66907735
97PRKDC0.66332553
98NEK10.64911474
99TTN0.64372117
100CSNK1D0.61153680
101* MAPK140.59840246
102YES10.59825456
103STK240.59771860
104NME10.59256959
105CSNK1E0.58746365
106JAK30.56661415
107DMPK0.54974800
108DYRK1B0.53618572
109NEK90.53134683
110SIK20.52899509
111PAK40.52538543
112RPS6KA50.52279898
113TIE10.50826347
114KSR20.49555106
115EIF2AK20.49538448
116PAK20.46950255
117AURKA0.46734414
118CSNK2A10.46210796
119CSNK2A20.45810210
120TAOK30.45772962
121VRK10.45689715
122LRRK20.45478860
123GSK3B0.44579244
124NME20.44211170
125AKT10.43914283
126MAP3K50.42952923
127PRKACB0.42849006
128LATS20.42281007
129MAPK100.41846224
130MAPK10.40969458
131FLT30.40499462
132NLK0.38884643
133EPHA30.38119569
134TEC0.37663850
135MAPK80.36977948
136SIK10.35697190
137CSNK1A1L0.35437579
138AKT20.34612647

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.04285098
2Spliceosome_Homo sapiens_hsa030402.87918297
3RNA transport_Homo sapiens_hsa030132.85094099
4DNA replication_Homo sapiens_hsa030302.84760534
5Cell cycle_Homo sapiens_hsa041102.77007660
6Mismatch repair_Homo sapiens_hsa034302.75086693
7One carbon pool by folate_Homo sapiens_hsa006702.61001288
8mRNA surveillance pathway_Homo sapiens_hsa030152.55994237
9Fanconi anemia pathway_Homo sapiens_hsa034602.37009266
10Systemic lupus erythematosus_Homo sapiens_hsa053222.27686802
11Non-homologous end-joining_Homo sapiens_hsa034502.11215098
12Homologous recombination_Homo sapiens_hsa034402.08490977
13Proteasome_Homo sapiens_hsa030502.05332126
14Base excision repair_Homo sapiens_hsa034101.85052478
15Cysteine and methionine metabolism_Homo sapiens_hsa002701.84693690
16Nucleotide excision repair_Homo sapiens_hsa034201.84358192
17RNA degradation_Homo sapiens_hsa030181.80477223
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.77057334
19MicroRNAs in cancer_Homo sapiens_hsa052061.71760737
20Viral carcinogenesis_Homo sapiens_hsa052031.66829992
21p53 signaling pathway_Homo sapiens_hsa041151.65637840
22Basal transcription factors_Homo sapiens_hsa030221.63304785
23Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.57057913
24Protein export_Homo sapiens_hsa030601.54950403
25Lysine degradation_Homo sapiens_hsa003101.54549231
26RNA polymerase_Homo sapiens_hsa030201.42529843
27Herpes simplex infection_Homo sapiens_hsa051681.35991935
28HTLV-I infection_Homo sapiens_hsa051661.34794449
29Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.34690135
30Small cell lung cancer_Homo sapiens_hsa052221.33324949
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.32289479
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.31053843
33Chronic myeloid leukemia_Homo sapiens_hsa052201.30123270
34Adherens junction_Homo sapiens_hsa045201.26392357
35Antigen processing and presentation_Homo sapiens_hsa046121.24955908
36TGF-beta signaling pathway_Homo sapiens_hsa043501.22676600
37Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19336004
38Basal cell carcinoma_Homo sapiens_hsa052171.14893990
39Primary immunodeficiency_Homo sapiens_hsa053401.14053905
40Epstein-Barr virus infection_Homo sapiens_hsa051691.13933475
41Steroid biosynthesis_Homo sapiens_hsa001001.13302070
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.13083335
43Hippo signaling pathway_Homo sapiens_hsa043901.11196482
44NF-kappa B signaling pathway_Homo sapiens_hsa040641.10395237
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.10185147
46Colorectal cancer_Homo sapiens_hsa052101.08535827
47Oocyte meiosis_Homo sapiens_hsa041141.06193426
48Notch signaling pathway_Homo sapiens_hsa043301.04224811
49mTOR signaling pathway_Homo sapiens_hsa041501.01056681
50T cell receptor signaling pathway_Homo sapiens_hsa046601.00899950
51Folate biosynthesis_Homo sapiens_hsa007900.99108970
52Prostate cancer_Homo sapiens_hsa052150.96316206
53Alcoholism_Homo sapiens_hsa050340.95570661
54Propanoate metabolism_Homo sapiens_hsa006400.93768918
55Viral myocarditis_Homo sapiens_hsa054160.93360473
56Pyrimidine metabolism_Homo sapiens_hsa002400.93322541
57Hepatitis B_Homo sapiens_hsa051610.92360416
58Endometrial cancer_Homo sapiens_hsa052130.84723866
59Proteoglycans in cancer_Homo sapiens_hsa052050.84066604
60Pancreatic cancer_Homo sapiens_hsa052120.83923052
61Selenocompound metabolism_Homo sapiens_hsa004500.83434145
62Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81848276
63Non-small cell lung cancer_Homo sapiens_hsa052230.81179812
64Thyroid cancer_Homo sapiens_hsa052160.79764742
65Pyruvate metabolism_Homo sapiens_hsa006200.79629808
66Wnt signaling pathway_Homo sapiens_hsa043100.78510646
67Measles_Homo sapiens_hsa051620.77432898
68FoxO signaling pathway_Homo sapiens_hsa040680.76385101
69B cell receptor signaling pathway_Homo sapiens_hsa046620.73784179
70Pathways in cancer_Homo sapiens_hsa052000.69804889
71Hedgehog signaling pathway_Homo sapiens_hsa043400.67090135
72Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.66445116
73Apoptosis_Homo sapiens_hsa042100.64094528
74Acute myeloid leukemia_Homo sapiens_hsa052210.63938321
75Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.63669470
76Dorso-ventral axis formation_Homo sapiens_hsa043200.63301854
77Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63138305
78Central carbon metabolism in cancer_Homo sapiens_hsa052300.63059930
79Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62052695
80Caffeine metabolism_Homo sapiens_hsa002320.60082673
81NOD-like receptor signaling pathway_Homo sapiens_hsa046210.59827994
82Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59372471
83Influenza A_Homo sapiens_hsa051640.59071433
84Ribosome_Homo sapiens_hsa030100.58544560
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.57772768
86Huntingtons disease_Homo sapiens_hsa050160.57190386
87Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.56047831
88Prolactin signaling pathway_Homo sapiens_hsa049170.55482980
89Toxoplasmosis_Homo sapiens_hsa051450.53323013
90Hematopoietic cell lineage_Homo sapiens_hsa046400.52879416
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.52772461
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.52539714
93Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.52291098
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.51872914
95Circadian rhythm_Homo sapiens_hsa047100.50387872
96Renal cell carcinoma_Homo sapiens_hsa052110.50233469
97AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.49941917
98Glioma_Homo sapiens_hsa052140.49456163
99Melanoma_Homo sapiens_hsa052180.49324251
100Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48335481
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48119276
102Biosynthesis of amino acids_Homo sapiens_hsa012300.47265474
103Focal adhesion_Homo sapiens_hsa045100.47216543
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47114149
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.46649580
106Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.46482900
107Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.45643354
108HIF-1 signaling pathway_Homo sapiens_hsa040660.45170809
109Bladder cancer_Homo sapiens_hsa052190.42497379
110Legionellosis_Homo sapiens_hsa051340.42323639
111Tight junction_Homo sapiens_hsa045300.42244974
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.41157328
113Insulin resistance_Homo sapiens_hsa049310.38824078
114Purine metabolism_Homo sapiens_hsa002300.38750618
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37363668
116TNF signaling pathway_Homo sapiens_hsa046680.37342388
117Carbon metabolism_Homo sapiens_hsa012000.36788911
118Ovarian steroidogenesis_Homo sapiens_hsa049130.36432013
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36307931
120Osteoclast differentiation_Homo sapiens_hsa043800.34283903
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33947072
122PI3K-Akt signaling pathway_Homo sapiens_hsa041510.33284903
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33129197
124AMPK signaling pathway_Homo sapiens_hsa041520.32449155
125Platelet activation_Homo sapiens_hsa046110.31464942
126Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30642477
127Fatty acid elongation_Homo sapiens_hsa000620.26866472
128Regulation of autophagy_Homo sapiens_hsa041400.25934899
129Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.24961926
130ErbB signaling pathway_Homo sapiens_hsa040120.23521783
131Inositol phosphate metabolism_Homo sapiens_hsa005620.20795950
132Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.20506020
133Metabolic pathways_Homo sapiens_hsa011000.17735733
134Shigellosis_Homo sapiens_hsa051310.14813901
135Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.14395962
136Olfactory transduction_Homo sapiens_hsa047400.12931975

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