IVL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intermediate filament organization (GO:0045109)8.41881262
2* keratinocyte differentiation (GO:0030216)7.56508886
3multicellular organismal water homeostasis (GO:0050891)7.51053706
4* peptide cross-linking (GO:0018149)6.71785996
5water homeostasis (GO:0030104)6.42723897
6hemidesmosome assembly (GO:0031581)6.31803735
7epidermis development (GO:0008544)6.23080461
8bundle of His cell to Purkinje myocyte communication (GO:0086069)6.08639518
9* epidermal cell differentiation (GO:0009913)5.97840531
10skin morphogenesis (GO:0043589)5.95887550
11keratinocyte proliferation (GO:0043616)5.66607386
12sphingoid metabolic process (GO:0046519)5.64228484
13gap junction assembly (GO:0016264)5.56918870
14sphingosine metabolic process (GO:0006670)5.01988462
15intermediate filament cytoskeleton organization (GO:0045104)5.00348649
16keratinocyte development (GO:0003334)4.96547378
17fatty acid elongation (GO:0030497)4.95561245
18intermediate filament-based process (GO:0045103)4.87617747
19virion attachment to host cell (GO:0019062)4.75119515
20adhesion of symbiont to host cell (GO:0044650)4.75119515
21long-chain fatty acid biosynthetic process (GO:0042759)4.70699249
22regulation of ruffle assembly (GO:1900027)4.67119360
23diol metabolic process (GO:0034311)4.66701197
24positive regulation of interleukin-8 secretion (GO:2000484)4.66425337
25glucosamine-containing compound catabolic process (GO:1901072)4.39320536
26positive regulation of epidermal cell differentiation (GO:0045606)4.38093825
27hair follicle morphogenesis (GO:0031069)4.25984705
28positive regulation of hair cycle (GO:0042635)4.16815342
29positive regulation of hair follicle development (GO:0051798)4.16815342
30ectoderm development (GO:0007398)4.14047760
31regulation of transforming growth factor beta1 production (GO:0032908)3.97684056
32phosphatidylinositol acyl-chain remodeling (GO:0036149)3.89999309
33detection of bacterium (GO:0016045)3.85511897
34adhesion of symbiont to host (GO:0044406)3.82070557
35interferon-gamma secretion (GO:0072643)3.77543463
36linoleic acid metabolic process (GO:0043651)3.77280083
37negative regulation of interleukin-17 production (GO:0032700)3.75912301
38ventricular cardiac muscle cell action potential (GO:0086005)3.74333596
39regulation of chemokine secretion (GO:0090196)3.73506407
40regulation of keratinocyte proliferation (GO:0010837)3.65395128
41sequestering of metal ion (GO:0051238)3.64089849
42regulation of cell proliferation involved in kidney development (GO:1901722)3.63873182
43phosphatidylserine acyl-chain remodeling (GO:0036150)3.62977015
44regulation of phospholipase A2 activity (GO:0032429)3.61760004
45eyelid development in camera-type eye (GO:0061029)3.47634494
46detection of external biotic stimulus (GO:0098581)3.47095497
47regulation of hair follicle development (GO:0051797)3.46211635
48regulation of interleukin-8 secretion (GO:2000482)3.42864212
49negative regulation of keratinocyte proliferation (GO:0010839)3.40921648
50primary alcohol catabolic process (GO:0034310)3.37041911
51positive regulation of keratinocyte differentiation (GO:0045618)3.34467623
52regulation of keratinocyte differentiation (GO:0045616)3.32485887
53regulation of heart rate by cardiac conduction (GO:0086091)3.32333805
54atrioventricular valve morphogenesis (GO:0003181)3.31680854
55positive regulation of T cell chemotaxis (GO:0010820)3.29236123
56regulation of T cell chemotaxis (GO:0010819)3.29236123
57regulation of hypersensitivity (GO:0002883)3.28831749
58detection of other organism (GO:0098543)3.28384776
59ceramide biosynthetic process (GO:0046513)3.28345838
60positive regulation of epidermis development (GO:0045684)3.27229522
61polarized epithelial cell differentiation (GO:0030859)3.23034741
62positive regulation of glomerulus development (GO:0090193)3.21998097
63hair cycle process (GO:0022405)3.16302076
64molting cycle process (GO:0022404)3.16302076
65phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.16133122
66chemical homeostasis within a tissue (GO:0048875)3.14251739
67long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.12222035
68negative regulation of stress fiber assembly (GO:0051497)3.11723809
69epithelium development (GO:0060429)3.09188921
70lipoxygenase pathway (GO:0019372)3.08779211
71regulation of monocyte chemotaxis (GO:0090025)3.08707527
72phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.08504500
73G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.04840586
74cell-substrate junction assembly (GO:0007044)3.02773108
75cyclooxygenase pathway (GO:0019371)3.01701200
76alditol phosphate metabolic process (GO:0052646)3.00930355
77cell communication involved in cardiac conduction (GO:0086065)3.00562293
78regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.96797836
79phospholipid scrambling (GO:0017121)2.96055772
80regulation of hair cycle (GO:0042634)2.94790675
81detection of biotic stimulus (GO:0009595)2.92568290
82planar cell polarity pathway involved in neural tube closure (GO:0090179)2.91596486
83regulation of epidermal cell differentiation (GO:0045604)2.90139712
84surfactant homeostasis (GO:0043129)2.88997132
85defense response to fungus (GO:0050832)2.83907175
86citrulline biosynthetic process (GO:0019240)2.82830361
87viral transcription (GO:0019083)2.82175502
88positive regulation of cellular amide metabolic process (GO:0034250)2.81191161
89epithelial cell differentiation involved in prostate gland development (GO:0060742)2.78151724
90* epithelial cell differentiation (GO:0030855)2.75763682
91phosphatidylcholine acyl-chain remodeling (GO:0036151)2.75271410
92negative regulation of cell fate specification (GO:0009996)2.75132695
93cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.73472582
94intestinal epithelial cell development (GO:0060576)2.72408538
95positive regulation of monocyte chemotaxis (GO:0090026)2.71596673
96epithelial cell-cell adhesion (GO:0090136)2.69425476
97negative regulation of interferon-gamma production (GO:0032689)2.68039793
98regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.67914832
99regulation of glomerular filtration (GO:0003093)2.67764103
100establishment of planar polarity (GO:0001736)2.67310790
101establishment of tissue polarity (GO:0007164)2.67310790
102regulation of epidermis development (GO:0045682)2.67256476
103cardiac conduction (GO:0061337)2.63615605
104lateral sprouting from an epithelium (GO:0060601)2.63320546
105translational termination (GO:0006415)2.60132473
106positive regulation of cell cycle checkpoint (GO:1901978)2.59872074
107skin development (GO:0043588)2.59211418
108dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.58948655
109phospholipid catabolic process (GO:0009395)2.57905771
110regulation of natural killer cell differentiation (GO:0032823)2.57114922
111regulation of axon regeneration (GO:0048679)2.55738601
112regulation of neuron projection regeneration (GO:0070570)2.55738601
113prostaglandin biosynthetic process (GO:0001516)2.52842230
114prostanoid biosynthetic process (GO:0046457)2.52842230
115fatty-acyl-CoA metabolic process (GO:0035337)2.50384620
116negative regulation of kidney development (GO:0090185)2.48755095
117regulation of natural killer cell activation (GO:0032814)2.47459662
118gland morphogenesis (GO:0022612)2.46931192
119positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.44316546
120regulation of protein localization to cell surface (GO:2000008)2.42985605
121defense response to Gram-negative bacterium (GO:0050829)2.41638159
122long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.40513570
123hair follicle development (GO:0001942)2.39896363
124ephrin receptor signaling pathway (GO:0048013)2.39337002
125ethanol metabolic process (GO:0006067)2.39063085
126phospholipid efflux (GO:0033700)2.38396251
127phosphatidylserine metabolic process (GO:0006658)2.36105583
128cardiac right ventricle morphogenesis (GO:0003215)2.35836106
129sphingolipid biosynthetic process (GO:0030148)2.35295962
130cardiac muscle cell action potential involved in contraction (GO:0086002)2.32649203
131response to phenylpropanoid (GO:0080184)2.31792136
132wound healing (GO:0042060)2.28519251
133positive regulation of p38MAPK cascade (GO:1900745)2.25880648
134molting cycle (GO:0042303)15.9494630
135hair cycle (GO:0042633)15.9494630
136desmosome organization (GO:0002934)13.9634770
137* keratinization (GO:0031424)13.2711893
138establishment of skin barrier (GO:0061436)12.5064377
139regulation of water loss via skin (GO:0033561)11.2595448

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse5.35215664
2* P63_26484246_Chip-Seq_KERATINOCYTES_Human3.36211900
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.85946344
4SOX9_24532713_ChIP-Seq_HFSC_Mouse2.58846742
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.29928496
6* SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.19132171
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.16711051
8ESR2_21235772_ChIP-Seq_MCF-7_Human2.12457488
9* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.08495027
10* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.08495027
11TRIM28_21343339_ChIP-Seq_HEK293_Human2.08172932
12TP63_17297297_ChIP-ChIP_HaCaT_Human14.4110993
13FOXO3_23340844_ChIP-Seq_DLD1_Human1.97173887
14CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.77647705
15ZNF217_24962896_ChIP-Seq_MCF-7_Human1.57505571
16BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.57031603
17RARG_19884340_ChIP-ChIP_MEFs_Mouse1.56200644
18SOX2_20726797_ChIP-Seq_SW620_Human1.52549371
19ZNF263_19887448_ChIP-Seq_K562_Human1.49773562
20EGR1_19032775_ChIP-ChIP_M12_Human1.49147483
21TP63_23658742_ChIP-Seq_EP156T_Human1.44852678
22TP53_18474530_ChIP-ChIP_U2OS_Human1.42269310
23TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.38462240
24TP63_22573176_ChIP-Seq_HFKS_Human1.37949639
25STAT6_21828071_ChIP-Seq_BEAS2B_Human1.37394447
26TCF4_18268006_ChIP-ChIP_LS174T_Human1.33231241
27CJUN_26792858_Chip-Seq_BT549_Human1.31804424
28KLF5_25053715_ChIP-Seq_YYC3_Human1.26447610
29RUNX1_27514584_Chip-Seq_MCF-7_Human1.26153867
30RACK7_27058665_Chip-Seq_MCF-7_Human1.25021813
31GATA4_25053715_ChIP-Seq_YYC3_Human1.24503128
32* GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.24388712
33TP53_20018659_ChIP-ChIP_R1E_Mouse1.24148139
34GATA3_24758297_ChIP-Seq_MCF-7_Human1.23073258
35* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.19661370
36* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.19379914
37* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16035680
38HIF1A_21447827_ChIP-Seq_MCF-7_Human1.15840292
39ATF3_27146783_Chip-Seq_COLON_Human1.15781765
40SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.15163437
41* GATA6_21074721_ChIP-Seq_CACO-2_Human1.09083753
42CLOCK_20551151_ChIP-Seq_293T_Human1.08971791
43AHR_22903824_ChIP-Seq_MCF-7_Human1.08623847
44RXR_22108803_ChIP-Seq_LS180_Human1.07706130
45P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.06368150
46ERG_20517297_ChIP-Seq_VCAP_Human1.06186351
47SUZ12_27294783_Chip-Seq_ESCs_Mouse1.04744649
48UBF1/2_26484160_Chip-Seq_HMECs_Human1.04123555
49CEBPB_22108803_ChIP-Seq_LS180_Human1.02640398
50SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01573040
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01202979
52CTCF_20526341_ChIP-Seq_ESCs_Human1.00820273
53CTCF_27219007_Chip-Seq_Bcells_Human0.99927513
54ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.99732873
55* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99551008
56SMC4_20622854_ChIP-Seq_HELA_Human0.98638431
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96420265
58JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95975262
59ARNT_22903824_ChIP-Seq_MCF-7_Human0.95647494
60LXR_22292898_ChIP-Seq_THP-1_Human0.95085206
61CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.93056028
62TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92188440
63ELK3_25401928_ChIP-Seq_HUVEC_Human0.92103418
64* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.91977213
65JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.88426703
66STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.88229198
67JARID2_20075857_ChIP-Seq_MESCs_Mouse0.87673596
68SA1_27219007_Chip-Seq_ERYTHROID_Human0.86650635
69YY1_22570637_ChIP-Seq_MALME-3M_Human0.85538648
70EZH2_27294783_Chip-Seq_ESCs_Mouse0.84996809
71EED_16625203_ChIP-ChIP_MESCs_Mouse0.84056677
72GATA6_25053715_ChIP-Seq_YYC3_Human0.83981750
73CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.83776135
74CDX2_19796622_ChIP-Seq_MESCs_Mouse0.83359964
75ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.83303575
76DNAJC2_21179169_ChIP-ChIP_NT2_Human0.82576364
77SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.82277009
78* CSB_26484114_Chip-Seq_FIBROBLAST_Human0.82044319
79SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.81367249
80NANOG_20526341_ChIP-Seq_ESCs_Human0.80635343
81BCAT_22108803_ChIP-Seq_LS180_Human0.80605408
82BCOR_27268052_Chip-Seq_Bcells_Human0.80343197
83AR_21572438_ChIP-Seq_LNCaP_Human0.80309694
84EZH2_27304074_Chip-Seq_ESCs_Mouse0.79771830
85BMI1_23680149_ChIP-Seq_NPCS_Mouse0.79755119
86CDX2_20551321_ChIP-Seq_CACO-2_Human0.78380590
87ESR1_20079471_ChIP-ChIP_T-47D_Human0.78181748
88ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77630444
89E2F1_20622854_ChIP-Seq_HELA_Human0.77375052
90SOX2_27498859_Chip-Seq_STOMACH_Mouse0.76741366
91SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.76603246
92* VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.76554803
93CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.76354328
94PPAR_26484153_Chip-Seq_NCI-H1993_Human0.76104910
95TAF2_19829295_ChIP-Seq_ESCs_Human0.75989609
96SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.75274024
97BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.75086778
98SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.73772684
99P53_21459846_ChIP-Seq_SAOS-2_Human0.73506946
100FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.72912482
101RBPJ_21746931_ChIP-Seq_IB4_Human0.72662019
102FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.71389497
103ERG_21242973_ChIP-ChIP_JURKAT_Human0.71331979
104TCF4_22108803_ChIP-Seq_LS180_Human0.71100209
105RNF2_27304074_Chip-Seq_ESCs_Mouse0.71052217
106AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.70639135
107NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.70529094
108FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.70070522
109RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.69204840
110HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.68487185
111SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.68093022
112PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.66865417
113* HNFA_21074721_ChIP-Seq_CACO-2_Human0.66855512
114FOXM1_26456572_ChIP-Seq_MCF-7_Human0.65868005
115P300_27058665_Chip-Seq_ZR-75-30cells_Human0.65443831
116EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.64611176
117HTT_18923047_ChIP-ChIP_STHdh_Human0.59621775
118RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.59383477
119SA1_27219007_Chip-Seq_Bcells_Human0.59081762
120PPARA_22158963_ChIP-Seq_LIVER_Mouse0.58914917
121P68_20966046_ChIP-Seq_HELA_Human0.58353025
122KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.58232674
123GATA2_21666600_ChIP-Seq_HMVEC_Human0.58188945
124TBX20_22080862_ChIP-Seq_HEART_Mouse0.57873475
125TBX20_22328084_ChIP-Seq_HEART_Mouse0.57873475
126BCL6_27268052_Chip-Seq_Bcells_Human0.52961674
127TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.50597670
128* GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.50223242

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier7.74900504
2MP0005275_abnormal_skin_tensile5.89076034
3MP0010234_abnormal_vibrissa_follicle5.26825895
4MP0000579_abnormal_nail_morphology5.04317908
5MP0005501_abnormal_skin_physiology4.86926407
6MP0003941_abnormal_skin_development4.23855756
7MP0004381_abnormal_hair_follicle4.20645717
8MP0002098_abnormal_vibrissa_morphology4.19685564
9MP0000647_abnormal_sebaceous_gland3.65577724
10MP0001216_abnormal_epidermal_layer3.35294489
11MP0002060_abnormal_skin_morphology3.31766575
12MP0002254_reproductive_system_inflammat3.11038162
13MP0010771_integument_phenotype2.98143806
14MP0005451_abnormal_body_composition2.98061602
15MP0010678_abnormal_skin_adnexa2.92695360
16MP0000383_abnormal_hair_follicle2.87667252
17MP0004947_skin_inflammation2.81093991
18MP0000427_abnormal_hair_cycle2.79714682
19MP0000377_abnormal_hair_follicle2.79325017
20MP0003453_abnormal_keratinocyte_physiol2.73492922
21MP0003705_abnormal_hypodermis_morpholog2.49984289
22MP0004885_abnormal_endolymph2.47785579
23MP0005377_hearing/vestibular/ear_phenot2.23337853
24MP0003878_abnormal_ear_physiology2.23337853
25MP0000467_abnormal_esophagus_morphology1.97397842
26MP0000762_abnormal_tongue_morphology1.72743471
27MP0001243_abnormal_dermal_layer1.70591275
28MP0009931_abnormal_skin_appearance1.68444056
29MP0003566_abnormal_cell_adhesion1.68021909
30MP0000367_abnormal_coat/_hair1.65859385
31MP0005367_renal/urinary_system_phenotyp1.57807759
32MP0000516_abnormal_urinary_system1.57807759
33MP0001191_abnormal_skin_condition1.50055680
34MP0004185_abnormal_adipocyte_glucose1.40282526
35MP0001346_abnormal_lacrimal_gland1.37773163
36MP0000566_synostosis1.23754098
37MP0002009_preneoplasia1.22904389
38MP0010386_abnormal_urinary_bladder1.15794092
39MP0002234_abnormal_pharynx_morphology1.12426064
40MP0003191_abnormal_cellular_cholesterol1.10578099
41MP0004043_abnormal_pH_regulation1.03721351
42MP0009053_abnormal_anal_canal1.00520808
43MP0001851_eye_inflammation0.97875122
44MP0010352_gastrointestinal_tract_polyps0.96685299
45MP0001340_abnormal_eyelid_morphology0.85809736
46MP0002877_abnormal_melanocyte_morpholog0.83978376
47MP0000465_gastrointestinal_hemorrhage0.82138780
48MP0004782_abnormal_surfactant_physiolog0.80467459
49MP0005075_abnormal_melanosome_morpholog0.77914770
50MP0006054_spinal_hemorrhage0.75828603
51MP0000627_abnormal_mammary_gland0.73910132
52MP0009379_abnormal_foot_pigmentation0.71637969
53MP0005023_abnormal_wound_healing0.71575664
54MP0000537_abnormal_urethra_morphology0.70709038
55MP0003315_abnormal_perineum_morphology0.67384680
56MP0003011_delayed_dark_adaptation0.62309086
57MP0003950_abnormal_plasma_membrane0.61330036
58MP0008004_abnormal_stomach_pH0.59117900
59MP0001784_abnormal_fluid_regulation0.59102016
60MP0010030_abnormal_orbit_morphology0.57772505
61MP0004264_abnormal_extraembryonic_tissu0.57491118
62MP0002095_abnormal_skin_pigmentation0.53657025
63MP0002177_abnormal_outer_ear0.53036069
64MP0002006_tumorigenesis0.52606646
65MP0003755_abnormal_palate_morphology0.51439860
66MP0001188_hyperpigmentation0.48996034
67MP0003385_abnormal_body_wall0.47420898
68MP0008260_abnormal_autophagy0.47072488
69MP0004272_abnormal_basement_membrane0.45493644
70MP0002249_abnormal_larynx_morphology0.44231455
71MP0004019_abnormal_vitamin_homeostasis0.44193434
72MP0005409_darkened_coat_color0.43390587
73MP0002166_altered_tumor_susceptibility0.42759837
74MP0002277_abnormal_respiratory_mucosa0.42714452
75MP0009384_cardiac_valve_regurgitation0.42387038
76MP0000538_abnormal_urinary_bladder0.40164379
77MP0002282_abnormal_trachea_morphology0.38921139
78MP0003638_abnormal_response/metabolism_0.36503821
79MP0002111_abnormal_tail_morphology0.36412150
80MP0000678_abnormal_parathyroid_gland0.36069392
81MP0002148_abnormal_hypersensitivity_rea0.35283236
82MP0000470_abnormal_stomach_morphology0.35269938
83MP0003763_abnormal_thymus_physiology0.34911571
84MP0001849_ear_inflammation0.33686509
85MP0003436_decreased_susceptibility_to0.32326671
86MP0005666_abnormal_adipose_tissue0.30905845
87MP0005248_abnormal_Harderian_gland0.30353393
88MP0008789_abnormal_olfactory_epithelium0.30273028
89MP0005508_abnormal_skeleton_morphology0.30047484
90MP0008438_abnormal_cutaneous_collagen0.29643221
91MP0005375_adipose_tissue_phenotype0.29542764
92MP0004197_abnormal_fetal_growth/weight/0.29525752
93MP0009780_abnormal_chondrocyte_physiolo0.29359563
94MP0002233_abnormal_nose_morphology0.28984758
95MP0001984_abnormal_olfaction0.28800576
96MP0005076_abnormal_cell_differentiation0.26395650
97MP0003136_yellow_coat_color0.25570368
98MP0000432_abnormal_head_morphology0.25440596
99MP0000613_abnormal_salivary_gland0.25372875
100MP0005193_abnormal_anterior_eye0.24601507
101MP0002697_abnormal_eye_size0.24466562
102MP0000015_abnormal_ear_pigmentation0.23223910
103MP0005394_taste/olfaction_phenotype0.22985290
104MP0005499_abnormal_olfactory_system0.22985290
105MP0008569_lethality_at_weaning0.22841177
106MP0002133_abnormal_respiratory_system0.22343487
107MP0005388_respiratory_system_phenotype0.22343487
108MP0005623_abnormal_meninges_morphology0.22104083
109MP0002896_abnormal_bone_mineralization0.20544265
110MP0005257_abnormal_intraocular_pressure0.20404042
111MP0010155_abnormal_intestine_physiology0.20317796
112MP0001765_abnormal_ion_homeostasis0.20115050
113MP0000858_altered_metastatic_potential0.20091021
114MP0001186_pigmentation_phenotype0.19829105
115MP0002090_abnormal_vision0.19394639
116MP0009333_abnormal_splenocyte_physiolog0.19277317
117MP0001485_abnormal_pinna_reflex0.17953486
118MP0000685_abnormal_immune_system0.17580616
119MP0001542_abnormal_bone_strength0.17536998
120MP0009250_abnormal_appendicular_skeleto0.17199958
121MP0000003_abnormal_adipose_tissue0.17060652
122MP0003936_abnormal_reproductive_system0.16657064
123MP0008961_abnormal_basal_metabolism0.15187170
124MP0003045_fibrosis0.15015257
125MP0003300_gastrointestinal_ulcer0.14772924
126MP0003828_pulmonary_edema0.13556284
127MP0001177_atelectasis0.12851172
128MP0002075_abnormal_coat/hair_pigmentati0.11040287
129MP0003448_altered_tumor_morphology0.09884475
130MP0009840_abnormal_foam_cell0.08452017

Predicted human phenotypes

RankGene SetZ-score
1Hypotrichosis (HP:0001006)9.44262253
2Woolly hair (HP:0002224)7.80624545
3Abnormality of nail color (HP:0100643)7.73483887
4Increased IgE level (HP:0003212)6.85230526
5Palmoplantar hyperkeratosis (HP:0000972)6.63896335
6Plantar hyperkeratosis (HP:0007556)6.37248928
7Palmar hyperkeratosis (HP:0010765)6.25821051
8Congenital ichthyosiform erythroderma (HP:0007431)6.15693966
9Right ventricular cardiomyopathy (HP:0011663)5.85028036
10Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.80334279
11Onycholysis (HP:0001806)5.60651319
12Erythema (HP:0010783)5.52418319
13Parakeratosis (HP:0001036)5.27092501
14Pili torti (HP:0003777)5.26378516
15Nail dystrophy (HP:0008404)5.13838107
16Brittle hair (HP:0002299)5.05369892
17Erythroderma (HP:0001019)4.95706687
18Fragile nails (HP:0001808)4.76427038
19Lip pit (HP:0100267)4.75186769
20Natal tooth (HP:0000695)4.57894541
21Conjunctival hamartoma (HP:0100780)4.03781549
22Milia (HP:0001056)3.92913375
23Thick nail (HP:0001805)3.91910602
24Abnormal hair laboratory examination (HP:0003328)3.89097882
25Abnormal blistering of the skin (HP:0008066)3.81558512
26Abnormality of hair growth rate (HP:0011363)3.71090102
27Slow-growing hair (HP:0002217)3.71090102
28Advanced eruption of teeth (HP:0006288)3.69339361
29Corneal erosion (HP:0200020)3.64104094
30Ectropion (HP:0000656)3.61690184
31Absent eyelashes (HP:0000561)3.51755249
32Gangrene (HP:0100758)3.43757200
33Hypohidrosis (HP:0000966)3.35044496
34Sparse eyelashes (HP:0000653)3.33644219
35Curly hair (HP:0002212)3.28003084
36Dry hair (HP:0011359)3.25962035
37Palmoplantar keratoderma (HP:0000982)3.23016791
38Hyporeflexia of lower limbs (HP:0002600)3.15461303
39Amniotic constriction ring (HP:0009775)3.13887607
40Abnormality of placental membranes (HP:0011409)3.13887607
41Alopecia of scalp (HP:0002293)3.09501145
42Ventricular tachycardia (HP:0004756)3.06422970
43Absent hair (HP:0002298)3.05505795
44Sparse scalp hair (HP:0002209)3.05478222
45Pruritus (HP:0000989)3.03253467
46Distal lower limb muscle weakness (HP:0009053)2.97818272
47Pustule (HP:0200039)2.89269648
48Congenital, generalized hypertrichosis (HP:0004540)2.66845558
49Furrowed tongue (HP:0000221)2.62771509
50Concave nail (HP:0001598)2.54673528
51Follicular hyperkeratosis (HP:0007502)2.50747565
52Acanthosis nigricans (HP:0000956)2.46790373
53Popliteal pterygium (HP:0009756)2.46608431
54Abnormality of the axillary hair (HP:0100134)2.39171426
55Abnormality of secondary sexual hair (HP:0009888)2.39171426
56Ridged nail (HP:0001807)2.38281127
57Epidermoid cyst (HP:0200040)2.37121941
58Hamartoma of the eye (HP:0010568)2.35977833
59Autoamputation (HP:0001218)2.31611207
60Atrophic scars (HP:0001075)2.27299123
61Multifactorial inheritance (HP:0001426)2.23171480
62Lack of skin elasticity (HP:0100679)2.21348043
63Aplasia cutis congenita (HP:0001057)2.19764477
64Axonal loss (HP:0003447)2.17666811
65Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.17599036
66Fine hair (HP:0002213)2.07551655
67Hypergammaglobulinemia (HP:0010702)2.06243017
68Abnormality of the gastric mucosa (HP:0004295)2.01364366
69Carious teeth (HP:0000670)2.01361519
70Corneal dystrophy (HP:0001131)2.00784420
71Abnormality of the salivary glands (HP:0010286)1.93678956
72Dry skin (HP:0000958)1.92560706
73Ventricular fibrillation (HP:0001663)1.91898054
74Eczematoid dermatitis (HP:0000976)1.91107393
75Areflexia of lower limbs (HP:0002522)1.86838693
76Severe Myopia (HP:0011003)1.86639169
77Selective tooth agenesis (HP:0001592)1.83050718
78Recurrent corneal erosions (HP:0000495)1.82480547
79Dehydration (HP:0001944)1.81483594
80Anonychia (HP:0001798)1.79933246
81Abnormality of the fingernails (HP:0001231)1.77418611
82Blepharitis (HP:0000498)1.74251560
83Abnormality of the neuromuscular junction (HP:0003398)1.73204036
84Fatigable weakness (HP:0003473)1.73204036
85Oral leukoplakia (HP:0002745)1.70786236
86Pterygium (HP:0001059)1.70292926
87Hoarse voice (HP:0001609)1.69026951
88Malignant hyperthermia (HP:0002047)1.67908597
89Round ear (HP:0100830)1.67477246
90Laryngomalacia (HP:0001601)1.67384435
91Fragile skin (HP:0001030)1.66397546
92Amelogenesis imperfecta (HP:0000705)1.65267810
93Hypoplastic labia majora (HP:0000059)1.65009656
94Segmental peripheral demyelination/remyelination (HP:0003481)1.63565061
95Paralysis (HP:0003470)1.62288076
96Abnormality of the frontal sinuses (HP:0002687)1.61938110
97Verrucae (HP:0200043)1.61121479
98Papilloma (HP:0012740)1.61121479
99Neck muscle weakness (HP:0000467)1.61040201
100Sepsis (HP:0100806)1.60880439
101Hyperhidrosis (HP:0000975)1.60537406
102Distal lower limb amyotrophy (HP:0008944)1.59563528
103Increased connective tissue (HP:0009025)1.58928731
104Down-sloping shoulders (HP:0200021)1.58863967
105Skin ulcer (HP:0200042)1.58315973
106Upper limb muscle weakness (HP:0003484)1.55367235
107Keratoconjunctivitis sicca (HP:0001097)1.54111169
108Xerostomia (HP:0000217)1.50555011
109Skin pits (HP:0100276)1.49118010
110Abnormality of the labia majora (HP:0012881)1.46582226
111Melanocytic nevus (HP:0000995)1.46096384
112Neonatal death (HP:0003811)1.45580884
113Achilles tendon contracture (HP:0001771)1.45227286
114Intention tremor (HP:0002080)1.44871238
115Hypoplasia of dental enamel (HP:0006297)1.44191742
116Hypoplastic toenails (HP:0001800)1.44099084
117Abnormality of the 2nd finger (HP:0004100)1.43767172
118Oligodontia (HP:0000677)1.42053300
119Trismus (HP:0000211)1.41235332
120Adenoma sebaceum (HP:0009720)1.41154133
121Angiofibromas (HP:0010615)1.41154133
122Urticaria (HP:0001025)1.40837289
123Abnormal hemoglobin (HP:0011902)1.39711833
124Type 1 muscle fiber predominance (HP:0003803)1.39028576
125Keratoconjunctivitis (HP:0001096)1.37862057
126Abnormal auditory evoked potentials (HP:0006958)1.36539219
127Recurrent bacterial skin infections (HP:0005406)1.35267307
128Ankyloglossia (HP:0010296)1.35030857
129Labial hypoplasia (HP:0000066)1.27917611
130Squamous cell carcinoma (HP:0002860)1.25381391

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK35.26258242
2MST1R4.21239660
3MST44.14591982
4FER3.62796686
5MAP3K33.46695224
6TGFBR13.37256640
7EPHA23.21169295
8TTN3.03610622
9PIK3CG2.71084079
10MAP3K22.60254269
11EPHB22.59889413
12RPS6KB22.54317047
13SGK2232.51849278
14SGK4942.51849278
15LATS12.41421934
16PIM22.18822683
17BLK2.05853189
18ERN11.91343548
19STK241.79053630
20CDK31.68983663
21MET1.67158248
22LRRK21.59944444
23MAPKAPK51.58353523
24TRPM71.56446356
25CDK121.46657872
26PTK61.44359576
27EEF2K1.35843055
28GRK61.35000673
29MAP2K61.31980430
30MAP3K111.27442498
31DYRK1B1.23455296
32TESK11.13563529
33IRAK11.13264359
34TAOK11.12593808
35STK101.11950879
36MYLK1.10831907
37MAPKAPK21.04710428
38EPHA31.03818099
39PRKCI1.02757087
40FGFR40.98783636
41ERBB30.96031878
42PRPF4B0.91465507
43FGFR10.90952371
44PTK20.90044450
45MAP3K10.88984904
46IRAK30.88263125
47EPHB10.87139649
48CDK60.86447525
49RIPK10.85042460
50ITK0.82515674
51BCR0.82231626
52MAP3K70.82179607
53LATS20.79987226
54WNK10.77187885
55MAP3K60.76785855
56STK380.75623164
57NTRK10.75614248
58IKBKB0.75600700
59MAP3K130.74965084
60MAPK70.74555554
61MAP3K90.74228169
62NTRK20.71946537
63RPS6KA40.71655318
64JAK30.70787932
65ARAF0.70276277
66GRK10.69989347
67PAK30.69966487
68TRIB30.69788805
69MAP3K140.69233260
70FGR0.68073981
71FLT30.65106332
72SMG10.63390166
73FGFR20.63325038
74STK110.60835154
75TGFBR20.60019344
76MAP2K10.59690702
77DMPK0.58663526
78KSR20.58114432
79PAK20.57660951
80LIMK10.56509755
81SGK10.55582557
82PRKCE0.55190310
83RPS6KA10.53490208
84PDGFRA0.52646052
85ILK0.52459644
86PRKD20.51617185
87MAP3K120.51438385
88TNK20.51176341
89PRKD10.49775190
90PBK0.49029856
91FGFR30.47866671
92CSNK1D0.45897343
93MAP2K20.45507243
94MAP2K30.45256046
95ABL20.44652364
96RET0.43998605
97SIK10.43458672
98IRAK20.42762134
99DDR20.42437935
100LMTK20.41961092
101IRAK40.41762721
102MAP3K50.41621224
103STK30.41043698
104SGK30.40721497
105IKBKE0.40351963
106ROCK10.40245695
107CDC42BPA0.40215435
108MTOR0.39816348
109TYRO30.37829671
110HCK0.35735347
111ERBB20.34692892
112NEK60.33399143
113MAPK40.32929221
114BMX0.32773603
115FRK0.32581396
116ERBB40.31457498
117STK38L0.30930259
118ADRBK10.30209763
119OBSCN0.29809358
120TYK20.29102772
121PDGFRB0.29069293
122MOS0.28723787
123RPS6KB10.28157457
124CSK0.26319660
125ROCK20.26098667
126BMPR20.25583309
127BRD40.25212710
128SYK0.25107686
129SRC0.24953523
130FYN0.24081287
131NME10.23415649
132PKN10.23401514
133SIK30.23124347
134TAOK20.23119184
135MAP3K100.21905436
136PRKCA0.21262224
137GSK3A0.21016839
138MAP2K40.20736935
139MARK20.20499741

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.41640600
2Linoleic acid metabolism_Homo sapiens_hsa005913.71278471
3alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.70065155
4Sphingolipid metabolism_Homo sapiens_hsa006003.31771167
5Arachidonic acid metabolism_Homo sapiens_hsa005902.89674704
6Cyanoamino acid metabolism_Homo sapiens_hsa004602.84149255
7Fatty acid elongation_Homo sapiens_hsa000622.77211994
8Phenylalanine metabolism_Homo sapiens_hsa003602.21981130
9Ether lipid metabolism_Homo sapiens_hsa005652.20936385
10Histidine metabolism_Homo sapiens_hsa003402.18491305
11Ribosome_Homo sapiens_hsa030102.03170471
12Graft-versus-host disease_Homo sapiens_hsa053321.90711366
13Bladder cancer_Homo sapiens_hsa052191.78485324
14Basal cell carcinoma_Homo sapiens_hsa052171.67474831
15VEGF signaling pathway_Homo sapiens_hsa043701.53015388
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.52919618
17Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.48196723
18Tight junction_Homo sapiens_hsa045301.45165683
19Adherens junction_Homo sapiens_hsa045201.42179685
20ECM-receptor interaction_Homo sapiens_hsa045121.39574667
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.37496396
22Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.36894017
23Circadian rhythm_Homo sapiens_hsa047101.33729190
24Fat digestion and absorption_Homo sapiens_hsa049751.25538898
25Leukocyte transendothelial migration_Homo sapiens_hsa046701.24697808
26Vascular smooth muscle contraction_Homo sapiens_hsa042701.23237980
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.23079399
28Proteoglycans in cancer_Homo sapiens_hsa052051.22754502
29Axon guidance_Homo sapiens_hsa043601.21819633
30Hedgehog signaling pathway_Homo sapiens_hsa043401.19143468
31Sphingolipid signaling pathway_Homo sapiens_hsa040711.16971070
32Staphylococcus aureus infection_Homo sapiens_hsa051501.15757805
33Chemical carcinogenesis_Homo sapiens_hsa052041.15158299
34Choline metabolism in cancer_Homo sapiens_hsa052311.12446184
35Collecting duct acid secretion_Homo sapiens_hsa049661.12003414
36Hippo signaling pathway_Homo sapiens_hsa043901.11416402
37GnRH signaling pathway_Homo sapiens_hsa049121.09791147
38Tyrosine metabolism_Homo sapiens_hsa003501.09056151
39Amoebiasis_Homo sapiens_hsa051461.03000923
40ABC transporters_Homo sapiens_hsa020101.01242937
41Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99859925
42Steroid biosynthesis_Homo sapiens_hsa001000.99451381
43Retinol metabolism_Homo sapiens_hsa008300.96089040
44p53 signaling pathway_Homo sapiens_hsa041150.95986101
45Melanogenesis_Homo sapiens_hsa049160.95961552
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.95795421
47Pertussis_Homo sapiens_hsa051330.90365436
48Renal cell carcinoma_Homo sapiens_hsa052110.90023304
49Ras signaling pathway_Homo sapiens_hsa040140.89557389
50Antigen processing and presentation_Homo sapiens_hsa046120.88631253
51Pancreatic secretion_Homo sapiens_hsa049720.87093840
52ErbB signaling pathway_Homo sapiens_hsa040120.85031594
53Platelet activation_Homo sapiens_hsa046110.84277749
54Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82998027
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82868466
56MicroRNAs in cancer_Homo sapiens_hsa052060.82341529
57Phototransduction_Homo sapiens_hsa047440.77005679
58Serotonergic synapse_Homo sapiens_hsa047260.73271945
59Glycerophospholipid metabolism_Homo sapiens_hsa005640.71266421
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.69794962
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.69743614
62Renin secretion_Homo sapiens_hsa049240.68840808
63Hepatitis C_Homo sapiens_hsa051600.67918909
64Endocytosis_Homo sapiens_hsa041440.67847742
65HIF-1 signaling pathway_Homo sapiens_hsa040660.67690982
66beta-Alanine metabolism_Homo sapiens_hsa004100.67157656
67Focal adhesion_Homo sapiens_hsa045100.66561687
68Fructose and mannose metabolism_Homo sapiens_hsa000510.65468831
69Dorso-ventral axis formation_Homo sapiens_hsa043200.64875373
70Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64568083
71Mineral absorption_Homo sapiens_hsa049780.63869893
72Toxoplasmosis_Homo sapiens_hsa051450.63636637
73TGF-beta signaling pathway_Homo sapiens_hsa043500.62512546
74Rap1 signaling pathway_Homo sapiens_hsa040150.62225606
75Inositol phosphate metabolism_Homo sapiens_hsa005620.61015894
76Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.58600723
77Wnt signaling pathway_Homo sapiens_hsa043100.58421940
78Thyroid cancer_Homo sapiens_hsa052160.58400103
79AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.58254029
80Shigellosis_Homo sapiens_hsa051310.57825343
81NOD-like receptor signaling pathway_Homo sapiens_hsa046210.57161164
82Gastric acid secretion_Homo sapiens_hsa049710.57089001
83Oxytocin signaling pathway_Homo sapiens_hsa049210.56195680
84Fatty acid biosynthesis_Homo sapiens_hsa000610.55995567
85Pancreatic cancer_Homo sapiens_hsa052120.55877551
86Insulin signaling pathway_Homo sapiens_hsa049100.55079309
87Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.55062212
88Melanoma_Homo sapiens_hsa052180.54802394
89Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.54741995
90Long-term depression_Homo sapiens_hsa047300.54515941
91Glioma_Homo sapiens_hsa052140.54216131
92Galactose metabolism_Homo sapiens_hsa000520.53984878
93Notch signaling pathway_Homo sapiens_hsa043300.53698585
94Caffeine metabolism_Homo sapiens_hsa002320.53266536
95Jak-STAT signaling pathway_Homo sapiens_hsa046300.52513623
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52103424
97Influenza A_Homo sapiens_hsa051640.51837403
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51805522
99Olfactory transduction_Homo sapiens_hsa047400.51258432
100Acute myeloid leukemia_Homo sapiens_hsa052210.51167688
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51044421
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.50459108
103Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50243718
104Vibrio cholerae infection_Homo sapiens_hsa051100.49570264
105MAPK signaling pathway_Homo sapiens_hsa040100.49243043
106Hematopoietic cell lineage_Homo sapiens_hsa046400.48349116
107Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.44865198
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43570377
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43039985
110Estrogen signaling pathway_Homo sapiens_hsa049150.41942034
111Small cell lung cancer_Homo sapiens_hsa052220.41582475
112Malaria_Homo sapiens_hsa051440.41409968
113Steroid hormone biosynthesis_Homo sapiens_hsa001400.41195168
114T cell receptor signaling pathway_Homo sapiens_hsa046600.41016643
115Protein digestion and absorption_Homo sapiens_hsa049740.39329541
116Ovarian steroidogenesis_Homo sapiens_hsa049130.38048092
117Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37725412
118Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.37673396
119Endometrial cancer_Homo sapiens_hsa052130.37511132
120PPAR signaling pathway_Homo sapiens_hsa033200.37379073
121Osteoclast differentiation_Homo sapiens_hsa043800.37083357
122Glutamatergic synapse_Homo sapiens_hsa047240.36568546
123Rheumatoid arthritis_Homo sapiens_hsa053230.36180701
124Salmonella infection_Homo sapiens_hsa051320.36045498
125Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35974189
126Tuberculosis_Homo sapiens_hsa051520.35665082
127TNF signaling pathway_Homo sapiens_hsa046680.33979830
128Chronic myeloid leukemia_Homo sapiens_hsa052200.33748453
129Pathways in cancer_Homo sapiens_hsa052000.33612453
130Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33503994
131Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32568798
132Long-term potentiation_Homo sapiens_hsa047200.28505812
133Salivary secretion_Homo sapiens_hsa049700.25737693

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