IQCH

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.70342339
2piRNA metabolic process (GO:0034587)9.42797684
3binding of sperm to zona pellucida (GO:0007339)9.41632601
4cell-cell recognition (GO:0009988)9.35797891
5motile cilium assembly (GO:0044458)9.24445826
6cilium movement (GO:0003341)8.87711889
7reproduction (GO:0000003)8.82551930
8spermatid development (GO:0007286)8.61479800
9male meiosis (GO:0007140)8.50890861
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.50818780
11regulation of cilium movement (GO:0003352)7.76432728
12synaptonemal complex organization (GO:0070193)7.38528183
13single fertilization (GO:0007338)7.23347235
14synaptonemal complex assembly (GO:0007130)7.01571820
15sperm capacitation (GO:0048240)6.80984124
16DNA methylation involved in gamete generation (GO:0043046)6.50107000
17fertilization (GO:0009566)6.10660297
18spermatogenesis (GO:0007283)5.85198616
19male gamete generation (GO:0048232)5.82910906
20male meiosis I (GO:0007141)5.53341897
21ventricular system development (GO:0021591)5.46349331
22microtubule depolymerization (GO:0007019)5.45919174
23gamete generation (GO:0007276)5.36980644
24negative regulation of inclusion body assembly (GO:0090084)5.35743558
25chromosome organization involved in meiosis (GO:0070192)5.17634341
26organic cation transport (GO:0015695)5.12513748
27germ cell development (GO:0007281)5.12135948
28cellular process involved in reproduction in multicellular organism (GO:0022412)5.06612689
29microtubule bundle formation (GO:0001578)4.95367234
30microtubule severing (GO:0051013)4.84023247
31retinal cone cell development (GO:0046549)4.78400748
32meiotic nuclear division (GO:0007126)4.77654101
33calcium ion-dependent exocytosis (GO:0017156)4.70886530
34photoreceptor cell maintenance (GO:0045494)4.53820741
35cell recognition (GO:0008037)4.52800474
36protein localization to cilium (GO:0061512)4.45662749
37regulation of inclusion body assembly (GO:0090083)4.34254706
38meiosis I (GO:0007127)4.27312337
39retinal rod cell development (GO:0046548)4.27235620
40multicellular organismal reproductive process (GO:0048609)4.19162899
41meiotic cell cycle (GO:0051321)4.15112580
42left/right pattern formation (GO:0060972)4.08412587
43regulation of microtubule-based movement (GO:0060632)4.08407253
44intraciliary transport (GO:0042073)4.06088181
45spermatid nucleus differentiation (GO:0007289)4.02180839
46seminiferous tubule development (GO:0072520)3.99671864
47axoneme assembly (GO:0035082)3.94966867
48centriole assembly (GO:0098534)3.77931405
49nonmotile primary cilium assembly (GO:0035058)3.75540738
50monoubiquitinated protein deubiquitination (GO:0035520)3.75453572
51cell projection assembly (GO:0030031)3.62409623
52protein K11-linked deubiquitination (GO:0035871)3.61671841
53protein polyglutamylation (GO:0018095)3.59442153
54cilium organization (GO:0044782)3.52121826
55polyol catabolic process (GO:0046174)3.44971426
56genitalia morphogenesis (GO:0035112)3.43690862
57synapsis (GO:0007129)3.42467910
58multicellular organismal development (GO:0007275)3.40408266
59cilium assembly (GO:0042384)3.40328260
60centriole replication (GO:0007099)3.27854328
61cellular component assembly involved in morphogenesis (GO:0010927)3.23893812
62lactate metabolic process (GO:0006089)3.21846669
63protein refolding (GO:0042026)3.19916882
64glycerol ether metabolic process (GO:0006662)3.14717522
65microtubule-based movement (GO:0007018)3.11354747
66meiotic cell cycle process (GO:1903046)3.09392725
67cilium morphogenesis (GO:0060271)3.07665759
68regulation of meiosis I (GO:0060631)3.05787063
69negative regulation of organelle assembly (GO:1902116)3.02433273
70lateral ventricle development (GO:0021670)3.00721337
71nucleoside diphosphate phosphorylation (GO:0006165)2.96854985
72coenzyme catabolic process (GO:0009109)2.95713869
73determination of left/right symmetry (GO:0007368)2.95556954
74ether metabolic process (GO:0018904)2.93972982
75gene silencing by RNA (GO:0031047)2.93422382
76single strand break repair (GO:0000012)2.93052612
77determination of bilateral symmetry (GO:0009855)2.89593124
78microtubule-based process (GO:0007017)2.87585768
79smoothened signaling pathway (GO:0007224)2.81500778
80specification of symmetry (GO:0009799)2.81185518
81brain morphogenesis (GO:0048854)2.78427764
82regulation of spindle checkpoint (GO:0090231)2.77812597
83microtubule polymerization or depolymerization (GO:0031109)2.75090159
84glutathione derivative metabolic process (GO:1901685)2.73315147
85glutathione derivative biosynthetic process (GO:1901687)2.73315147
86regulation of autophagic vacuole assembly (GO:2000785)2.73146902
87DNA integration (GO:0015074)2.70441028
88organelle assembly (GO:0070925)2.69796587
89pyrimidine-containing compound transmembrane transport (GO:0072531)2.67212934
90alditol metabolic process (GO:0019400)2.65946773
91GTP biosynthetic process (GO:0006183)2.61874391
92intra-S DNA damage checkpoint (GO:0031573)2.60249100
93histone H2A acetylation (GO:0043968)2.59441663
94neural tube formation (GO:0001841)2.56722217
95DNA packaging (GO:0006323)2.56185357
96regulation of centriole replication (GO:0046599)2.55602165
97establishment of protein localization to Golgi (GO:0072600)2.53908632
98primary alcohol catabolic process (GO:0034310)2.53618009
99response to nitrosative stress (GO:0051409)2.52257719
100photoreceptor cell development (GO:0042461)2.46914248
101spinal cord motor neuron differentiation (GO:0021522)2.46273487
102nucleus organization (GO:0006997)2.45984574
103left/right axis specification (GO:0070986)2.45785612
104glycerol metabolic process (GO:0006071)2.42784310
105regulation of acrosome reaction (GO:0060046)2.42407731
106regulation of vacuole organization (GO:0044088)2.39615111
107vitamin transmembrane transport (GO:0035461)2.39298800
108sequestering of actin monomers (GO:0042989)2.39089210
109regulation of protein polyubiquitination (GO:1902914)2.38786969
110chromosome condensation (GO:0030261)2.37688909
111ubiquinone biosynthetic process (GO:0006744)2.35755565
112sulfate transmembrane transport (GO:1902358)2.35742373
113chaperone-mediated protein complex assembly (GO:0051131)2.34260148
114negative regulation of skeletal muscle tissue development (GO:0048642)2.34140774
115limb development (GO:0060173)2.34027017
116appendage development (GO:0048736)2.34027017
117protein targeting to Golgi (GO:0000042)2.33074668
118calcium ion import (GO:0070509)2.32328967
119terpenoid biosynthetic process (GO:0016114)2.32197889
120oocyte development (GO:0048599)2.31772592
121peptidyl-glutamic acid modification (GO:0018200)2.31698932
122replicative senescence (GO:0090399)2.31106670
123cellular ketone body metabolic process (GO:0046950)2.29916130
124eye photoreceptor cell development (GO:0042462)2.29443709
125carnitine transport (GO:0015879)2.28395012
126amino-acid betaine transport (GO:0015838)2.28395012
127resolution of meiotic recombination intermediates (GO:0000712)2.24358803
128neurotransmitter catabolic process (GO:0042135)2.20173787
129protein localization to Golgi apparatus (GO:0034067)2.19242325
130ubiquinone metabolic process (GO:0006743)2.18624438
131lung epithelium development (GO:0060428)2.18576464
132regulation of feeding behavior (GO:0060259)2.18517444
133one-carbon compound transport (GO:0019755)2.17289178
134regulation of centrosome duplication (GO:0010824)2.17113884
135ADP metabolic process (GO:0046031)2.15406708
136cytoplasmic microtubule organization (GO:0031122)2.14866128
137nucleotide transmembrane transport (GO:1901679)2.14016583
138retrograde transport, vesicle recycling within Golgi (GO:0000301)2.13986560
139microtubule-based transport (GO:0010970)2.13777507
140benzene-containing compound metabolic process (GO:0042537)2.13332753
141cilium or flagellum-dependent cell motility (GO:0001539)13.8321921
142fusion of sperm to egg plasma membrane (GO:0007342)12.7117875
143sperm motility (GO:0030317)11.9549437
144multicellular organism reproduction (GO:0032504)10.8823710
145acrosome assembly (GO:0001675)10.8614876
146axonemal dynein complex assembly (GO:0070286)10.5440586
147acrosome reaction (GO:0007340)10.5021084
148sperm-egg recognition (GO:0035036)10.4884538
149epithelial cilium movement (GO:0003351)10.1633384
150cell wall macromolecule catabolic process (GO:0016998)10.0593345
151cell wall macromolecule metabolic process (GO:0044036)10.0593345

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse7.59935578
2EZH2_22144423_ChIP-Seq_EOC_Human5.35610351
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.51961934
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.59550867
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.11404791
6IGF1R_20145208_ChIP-Seq_DFB_Human3.06185211
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.87031546
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.77290722
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.65855082
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.45329109
11AR_21572438_ChIP-Seq_LNCaP_Human2.30596125
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.24238584
13SALL1_21062744_ChIP-ChIP_HESCs_Human2.21356863
14CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.10203551
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.07936914
16EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.03575833
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.03116574
18NFE2_27457419_Chip-Seq_LIVER_Mouse2.02153536
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.00486941
20VDR_22108803_ChIP-Seq_LS180_Human2.00138648
21SUZ12_27294783_Chip-Seq_NPCs_Mouse1.99744273
22PCGF2_27294783_Chip-Seq_NPCs_Mouse1.99381953
23PIAS1_25552417_ChIP-Seq_VCAP_Human1.93273536
24* STAT3_23295773_ChIP-Seq_U87_Human1.92111711
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81436587
26PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.80206906
27TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.78790310
28TOP2B_26459242_ChIP-Seq_MCF-7_Human1.78240886
29EWS_26573619_Chip-Seq_HEK293_Human1.75613857
30NANOG_18555785_Chip-Seq_ESCs_Mouse1.69092759
31* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.65656239
32GBX2_23144817_ChIP-Seq_PC3_Human1.65568467
33EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.65299194
34KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.64281000
35BCAT_22108803_ChIP-Seq_LS180_Human1.63050104
36KDM2B_26808549_Chip-Seq_REH_Human1.60921439
37P53_22387025_ChIP-Seq_ESCs_Mouse1.59451671
38KLF5_20875108_ChIP-Seq_MESCs_Mouse1.59097607
39TAL1_26923725_Chip-Seq_HPCs_Mouse1.58098859
40RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.55426940
41FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.55143091
42KAP1_22055183_ChIP-Seq_ESCs_Mouse1.54861233
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.53912424
44STAT1_17558387_ChIP-Seq_HELA_Human1.53409275
45* RNF2_27304074_Chip-Seq_NSC_Mouse1.52826295
46STAT3_18555785_Chip-Seq_ESCs_Mouse1.52658082
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52250775
48NR3C1_21868756_ChIP-Seq_MCF10A_Human1.51212820
49TAF15_26573619_Chip-Seq_HEK293_Human1.50872458
50CBP_20019798_ChIP-Seq_JUKART_Human1.47788467
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.47788467
52* ARNT_22903824_ChIP-Seq_MCF-7_Human1.46431677
53OCT4_18555785_Chip-Seq_ESCs_Mouse1.45752190
54SUZ12_18555785_Chip-Seq_ESCs_Mouse1.45276517
55CMYC_18555785_Chip-Seq_ESCs_Mouse1.43982612
56P300_18555785_Chip-Seq_ESCs_Mouse1.43746911
57EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.42837575
58* ELK4_26923725_Chip-Seq_MESODERM_Mouse1.42620477
59MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.42078606
60* AR_25329375_ChIP-Seq_VCAP_Human1.41585276
61ZNF274_21170338_ChIP-Seq_K562_Hela1.40827693
62TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.40510901
63CRX_20693478_ChIP-Seq_RETINA_Mouse1.39268927
64E2F1_18555785_Chip-Seq_ESCs_Mouse1.38236448
65GATA1_26923725_Chip-Seq_HPCs_Mouse1.37023393
66* AHR_22903824_ChIP-Seq_MCF-7_Human1.36563732
67* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.36183874
68ESR1_20079471_ChIP-ChIP_T-47D_Human1.36133063
69KLF4_18555785_Chip-Seq_ESCs_Mouse1.33684181
70RUNX2_22187159_ChIP-Seq_PCA_Human1.30787450
71CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.30175910
72WDR5_24793694_ChIP-Seq_LNCAP_Human1.29986804
73REST_21632747_ChIP-Seq_MESCs_Mouse1.29559671
74ESRRB_18555785_Chip-Seq_ESCs_Mouse1.29545344
75* TCF4_22108803_ChIP-Seq_LS180_Human1.29322289
76SOX2_18555785_Chip-Seq_ESCs_Mouse1.28126516
77PU1_27457419_Chip-Seq_LIVER_Mouse1.27842367
78RUNX1_27457419_Chip-Seq_LIVER_Mouse1.27825328
79ER_23166858_ChIP-Seq_MCF-7_Human1.26716627
80OCT4_21477851_ChIP-Seq_ESCs_Mouse1.26672878
81POU3F2_20337985_ChIP-ChIP_501MEL_Human1.24849753
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24783895
83NMYC_18555785_Chip-Seq_ESCs_Mouse1.23775294
84HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23103302
85SOX2_19829295_ChIP-Seq_ESCs_Human1.22810230
86NANOG_19829295_ChIP-Seq_ESCs_Human1.22810230
87CDX2_22108803_ChIP-Seq_LS180_Human1.21747929
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21426785
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21426785
90ZFX_18555785_Chip-Seq_ESCs_Mouse1.21212656
91CTCF_18555785_Chip-Seq_ESCs_Mouse1.19627394
92CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.19023219
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18693274
94MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18654729
95ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18635231
96* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18155954
97CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.16547223
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16295671
99SMAD4_21799915_ChIP-Seq_A2780_Human1.16045812
100TP53_18474530_ChIP-ChIP_U2OS_Human1.14266923
101GF1_26923725_Chip-Seq_HPCs_Mouse1.14021503
102* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12696164
103* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.12434963
104PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12406101
105TCF4_23295773_ChIP-Seq_U87_Human1.11571082
106ETV1_20927104_ChIP-Seq_GIST48_Human1.11297957
107SMAD1_18555785_Chip-Seq_ESCs_Mouse1.10246133
108GABP_17652178_ChIP-ChIP_JURKAT_Human1.09214283
109* SMAD4_21741376_ChIP-Seq_EPCs_Human1.08995559
110FLI1_21867929_ChIP-Seq_TH2_Mouse1.08666151
111IRF1_19129219_ChIP-ChIP_H3396_Human1.08622387
112CTBP1_25329375_ChIP-Seq_LNCAP_Human1.08188234
113GATA3_21867929_ChIP-Seq_CD8_Mouse1.07036452
114PHF8_20622853_ChIP-Seq_HELA_Human1.06678539
115* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.06621877
116FUS_26573619_Chip-Seq_HEK293_Human1.06257437
117GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.06014420
118* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.05465637
119* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04698920
120* FOXA1_25329375_ChIP-Seq_VCAP_Human1.04698920
121SOX2_22085726_ChIP-Seq_NPCs_Mouse1.03879690
122TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03682099
123* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03596677
124* TP53_22573176_ChIP-Seq_HFKS_Human1.02409369
125SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.02119110
126PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.01844823
127AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01380889
128EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01370877
129* SOX2_21211035_ChIP-Seq_LN229_Gbm1.01124454
130* SMAD3_21741376_ChIP-Seq_EPCs_Human1.00682975
131SOX9_26525672_Chip-Seq_HEART_Mouse1.00650292
132OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99885558
133PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99694212
134NFYA_21822215_ChIP-Seq_K562_Human0.99235407
135ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.98934574
136AUTS2_25519132_ChIP-Seq_293T-REX_Human0.98641071
137GATA3_21867929_ChIP-Seq_TH1_Mouse0.98214707
138SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.96472104
139CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.96265011
140RBPJ_21746931_ChIP-Seq_IB4_Human0.96239787
141ERG_20517297_ChIP-Seq_VCAP_Human0.96056099
142HNFA_21074721_ChIP-Seq_CACO-2_Human0.95920636
143CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95897503
144* TBL1_22424771_ChIP-Seq_293T_Human0.94941718
145CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.94552683
146JUN_21703547_ChIP-Seq_K562_Human0.94008528
147NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.93197340
148NFYB_21822215_ChIP-Seq_K562_Human0.92890611
149* P300_19829295_ChIP-Seq_ESCs_Human0.92655626
150PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.92230538
151GF1B_26923725_Chip-Seq_HPCs_Mouse0.91531805
152VDR_24787735_ChIP-Seq_THP-1_Human0.90679615
153UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90266080
154CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89201501

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.50557861
2MP0001929_abnormal_gametogenesis4.88854673
3MP0008877_abnormal_DNA_methylation4.43991130
4MP0002210_abnormal_sex_determination3.47402197
5MP0002161_abnormal_fertility/fecundity2.87805218
6MP0001145_abnormal_male_reproductive2.74886385
7MP0002653_abnormal_ependyma_morphology2.47775543
8MP0000653_abnormal_sex_gland2.41946611
9MP0002160_abnormal_reproductive_system2.35426310
10MP0008875_abnormal_xenobiotic_pharmacok2.24471198
11MP0009046_muscle_twitch2.21629456
12MP0000383_abnormal_hair_follicle2.11634865
13MP0005410_abnormal_fertilization13.7873752
14MP0005499_abnormal_olfactory_system1.94903122
15MP0005394_taste/olfaction_phenotype1.94903122
16MP0004043_abnormal_pH_regulation1.94081492
17MP0003646_muscle_fatigue1.93791772
18MP0008789_abnormal_olfactory_epithelium1.91949797
19MP0005248_abnormal_Harderian_gland1.85371729
20MP0005623_abnormal_meninges_morphology1.74167782
21MP0005670_abnormal_white_adipose1.72389489
22MP0001348_abnormal_lacrimal_gland1.70342760
23MP0005075_abnormal_melanosome_morpholog1.61449243
24MP0010678_abnormal_skin_adnexa1.60803140
25MP0001984_abnormal_olfaction1.60499066
26MP0010386_abnormal_urinary_bladder1.55679892
27MP0003718_maternal_effect1.53987228
28MP0001529_abnormal_vocalization1.53423392
29MP0005389_reproductive_system_phenotype1.49614683
30MP0005647_abnormal_sex_gland1.49102923
31MP0004381_abnormal_hair_follicle1.47941698
32MP0000372_irregular_coat_pigmentation1.46670190
33MP0005083_abnormal_biliary_tract1.42291325
34MP0003878_abnormal_ear_physiology1.41201205
35MP0005377_hearing/vestibular/ear_phenot1.41201205
36MP0006072_abnormal_retinal_apoptosis1.41090701
37MP0003879_abnormal_hair_cell1.40607213
38MP0001986_abnormal_taste_sensitivity1.34899984
39MP0002102_abnormal_ear_morphology1.33295348
40MP0000427_abnormal_hair_cycle1.30997187
41MP0003937_abnormal_limbs/digits/tail_de1.28456240
42MP0002282_abnormal_trachea_morphology1.24987974
43MP0008058_abnormal_DNA_repair1.22219330
44MP0000631_abnormal_neuroendocrine_gland1.22215165
45MP0009697_abnormal_copulation1.20576023
46MP0000015_abnormal_ear_pigmentation1.17358769
47MP0002734_abnormal_mechanical_nocicepti1.13456822
48MP0001486_abnormal_startle_reflex1.13201379
49MP0005646_abnormal_pituitary_gland1.06741992
50MP0001502_abnormal_circadian_rhythm1.06262662
51MP0003656_abnormal_erythrocyte_physiolo1.03403073
52MP0005195_abnormal_posterior_eye1.02546746
53MP0002909_abnormal_adrenal_gland1.01546777
54MP0002229_neurodegeneration1.01469223
55MP0008995_early_reproductive_senescence1.01008681
56MP0001346_abnormal_lacrimal_gland0.99677434
57MP0003806_abnormal_nucleotide_metabolis0.98220030
58MP0002233_abnormal_nose_morphology0.92546361
59MP0002090_abnormal_vision0.91655113
60MP0002938_white_spotting0.90647383
61MP0002736_abnormal_nociception_after0.88581342
62MP0000566_synostosis0.88513314
63MP0001765_abnormal_ion_homeostasis0.86395124
64MP0008057_abnormal_DNA_replication0.83956772
65MP0003283_abnormal_digestive_organ0.83508660
66MP0002752_abnormal_somatic_nervous0.82879177
67MP0001919_abnormal_reproductive_system0.80918715
68MP0010030_abnormal_orbit_morphology0.80607300
69MP0004215_abnormal_myocardial_fiber0.78610292
70MP0009780_abnormal_chondrocyte_physiolo0.77829787
71MP0008872_abnormal_physiological_respon0.77657169
72MP0004085_abnormal_heartbeat0.77053673
73MP0001324_abnormal_eye_pigmentation0.76154878
74MP0000955_abnormal_spinal_cord0.75921164
75MP0006036_abnormal_mitochondrial_physio0.75706432
76MP0001661_extended_life_span0.75369646
77MP0004145_abnormal_muscle_electrophysio0.74331215
78MP0001944_abnormal_pancreas_morphology0.73542473
79MP0005551_abnormal_eye_electrophysiolog0.73399929
80MP0002837_dystrophic_cardiac_calcinosis0.72833550
81MP0000569_abnormal_digit_pigmentation0.72828895
82MP0000647_abnormal_sebaceous_gland0.72071420
83MP0005220_abnormal_exocrine_pancreas0.71632292
84MP0006035_abnormal_mitochondrial_morpho0.71387775
85MP0001119_abnormal_female_reproductive0.70498637
86MP0003861_abnormal_nervous_system0.69728246
87MP0001905_abnormal_dopamine_level0.69461400
88MP0005645_abnormal_hypothalamus_physiol0.69365438
89MP0003786_premature_aging0.69349175
90MP0005253_abnormal_eye_physiology0.65450423
91MP0001968_abnormal_touch/_nociception0.64786962
92MP0003942_abnormal_urinary_system0.62438549
93MP0004019_abnormal_vitamin_homeostasis0.62431805
94MP0001188_hyperpigmentation0.62036559
95MP0001963_abnormal_hearing_physiology0.61581768
96MP0003011_delayed_dark_adaptation0.60820381
97MP0002572_abnormal_emotion/affect_behav0.60038571
98MP0010094_abnormal_chromosome_stability0.58642845
99MP0002876_abnormal_thyroid_physiology0.56862577
100MP0003136_yellow_coat_color0.56514803
101MP0002735_abnormal_chemical_nociception0.56328420
102MP0004134_abnormal_chest_morphology0.56003946
103MP0006292_abnormal_olfactory_placode0.55618423
104MP0003787_abnormal_imprinting0.54966881
105MP0002168_other_aberrant_phenotype0.54734740
106MP0005174_abnormal_tail_pigmentation0.51372044
107MP0002067_abnormal_sensory_capabilities0.51053931
108MP0005408_hypopigmentation0.50721495
109MP0003699_abnormal_female_reproductive0.49209320
110MP0003880_abnormal_central_pattern0.48407717
111MP0002277_abnormal_respiratory_mucosa0.47897150
112MP0000026_abnormal_inner_ear0.45899066
113MP0005171_absent_coat_pigmentation0.44903572
114MP0002272_abnormal_nervous_system0.44472012
115MP0009745_abnormal_behavioral_response0.44469397
116MP0002132_abnormal_respiratory_system0.43146615
117MP0002009_preneoplasia0.41943121
118MP0004742_abnormal_vestibular_system0.41764991
119MP0006276_abnormal_autonomic_nervous0.41332712
120MP0003950_abnormal_plasma_membrane0.41332181
121MP0000778_abnormal_nervous_system0.40717200
122MP0002998_abnormal_bone_remodeling0.39305467
123MP0002557_abnormal_social/conspecific_i0.39237668
124MP0002177_abnormal_outer_ear0.38888639
125MP0004133_heterotaxia0.38194229
126MP0003890_abnormal_embryonic-extraembry0.37319589
127MP0000432_abnormal_head_morphology0.37227037
128MP0006082_CNS_inflammation0.36818086
129MP0002933_joint_inflammation0.36421485
130MP0000678_abnormal_parathyroid_gland0.36416680
131MP0003633_abnormal_nervous_system0.36255245
132MP0002148_abnormal_hypersensitivity_rea0.36234978
133MP0004142_abnormal_muscle_tone0.36215159
134MP0005391_vision/eye_phenotype0.36195104
135MP0008007_abnormal_cellular_replicative0.35951270
136MP0005395_other_phenotype0.35669519
137MP0001293_anophthalmia0.35558797
138MP0002928_abnormal_bile_duct0.34363442
139MP0009785_altered_susceptibility_to0.33011463
140MP0005636_abnormal_mineral_homeostasis0.32930838
141MP0001485_abnormal_pinna_reflex0.32772851
142MP0001764_abnormal_homeostasis0.32766915
143MP0008004_abnormal_stomach_pH0.31290934
144MP0002638_abnormal_pupillary_reflex0.30907789
145MP0000049_abnormal_middle_ear0.30685746

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.01039937
2Abnormal respiratory motile cilium morphology (HP:0005938)8.63682565
3Abnormal respiratory epithelium morphology (HP:0012253)8.63682565
4Abnormal ciliary motility (HP:0012262)7.68285296
5Rhinitis (HP:0012384)7.43290997
6Chronic bronchitis (HP:0004469)6.00504297
7Infertility (HP:0000789)5.42906495
8Nasal polyposis (HP:0100582)5.14995032
9Nephronophthisis (HP:0000090)4.50182889
10Bronchiectasis (HP:0002110)4.19501159
11Abnormality of the nasal mucosa (HP:0000433)4.10879817
12Occipital encephalocele (HP:0002085)3.93576250
13Tubulointerstitial nephritis (HP:0001970)3.83490133
14Bronchitis (HP:0012387)3.66451030
15Abnormality of the renal medulla (HP:0100957)3.64871600
16Recurrent sinusitis (HP:0011108)3.20565088
17Medial flaring of the eyebrow (HP:0010747)3.07563616
18Abnormal spermatogenesis (HP:0008669)3.02072493
19Absent rod-and cone-mediated responses on ERG (HP:0007688)2.89827775
20Recurrent otitis media (HP:0000403)2.83045876
21Tubulointerstitial abnormality (HP:0001969)2.78359685
22Male infertility (HP:0003251)2.72941972
23Molar tooth sign on MRI (HP:0002419)2.66910588
24Abnormality of midbrain morphology (HP:0002418)2.66910588
25Tubular atrophy (HP:0000092)2.63002861
26Selective tooth agenesis (HP:0001592)2.62648230
27Congenital hepatic fibrosis (HP:0002612)2.49652807
28Azoospermia (HP:0000027)2.45317823
29Fibular hypoplasia (HP:0003038)2.43810068
30Abnormal rod and cone electroretinograms (HP:0008323)2.39294332
31Male pseudohermaphroditism (HP:0000037)2.38651172
32Postaxial foot polydactyly (HP:0001830)2.38600709
33Gonadotropin excess (HP:0000837)2.33709013
34Sclerocornea (HP:0000647)2.33476837
35Anencephaly (HP:0002323)2.30605639
36Pancreatic fibrosis (HP:0100732)2.23968826
37Bony spicule pigmentary retinopathy (HP:0007737)2.23068709
38Abnormal biliary tract physiology (HP:0012439)2.22986131
39Bile duct proliferation (HP:0001408)2.22986131
40Supernumerary spleens (HP:0009799)2.16419421
41Impulsivity (HP:0100710)2.15407087
42Renal dysplasia (HP:0000110)2.12539514
43Stage 5 chronic kidney disease (HP:0003774)2.12349187
44Abnormality of the renal cortex (HP:0011035)2.10624451
45Recurrent bronchitis (HP:0002837)2.10415519
46Taurodontia (HP:0000679)2.09318547
47Abnormality of permanent molar morphology (HP:0011071)2.09318547
48Abnormality of the dental root (HP:0006486)2.09318547
49Chronic hepatic failure (HP:0100626)2.07910098
50Abnormality of molar morphology (HP:0011070)2.06728374
51Abnormality of molar (HP:0011077)2.06728374
52True hermaphroditism (HP:0010459)2.06706585
53Absent frontal sinuses (HP:0002688)2.06225521
54Preaxial hand polydactyly (HP:0001177)2.05751344
55Decreased central vision (HP:0007663)2.05316879
56Abnormality of the lower motor neuron (HP:0002366)2.02572096
57Median cleft lip (HP:0000161)2.01198485
58Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.3988632
59Dynein arm defect of respiratory motile cilia (HP:0012255)12.1785008
60Absent/shortened dynein arms (HP:0200106)12.1785008
61Large for gestational age (HP:0001520)1.94797081
62Chronic sinusitis (HP:0011109)1.93276633
63Abnormality of the dental pulp (HP:0006479)1.91889086
64Abnormal drinking behavior (HP:0030082)1.91279993
65Polydipsia (HP:0001959)1.91279993
66Postaxial hand polydactyly (HP:0001162)1.89534819
67Type II lissencephaly (HP:0007260)1.88786114
68Congenital primary aphakia (HP:0007707)1.86763332
69Facial cleft (HP:0002006)1.85988883
70Hypoplasia of the capital femoral epiphysis (HP:0003090)1.84832051
71Furrowed tongue (HP:0000221)1.84378931
72Gait imbalance (HP:0002141)1.84118443
73Abnormality of macular pigmentation (HP:0008002)1.83949331
74Tubulointerstitial fibrosis (HP:0005576)1.83125020
75Cerebellar dysplasia (HP:0007033)1.83025711
76Dyschromatopsia (HP:0007641)1.81157964
77Impaired proprioception (HP:0010831)1.80582812
78Hyperinsulinemic hypoglycemia (HP:0000825)1.78539463
79J-shaped sella turcica (HP:0002680)1.77857733
80Nephrogenic diabetes insipidus (HP:0009806)1.77523230
81Aplasia/Hypoplasia of the lens (HP:0008063)1.76139727
82Vascular calcification (HP:0004934)1.74619966
83Hyperactive renin-angiotensin system (HP:0000841)1.74591934
84Retinitis pigmentosa (HP:0000510)1.72894151
85Spastic tetraparesis (HP:0001285)1.71862421
86Prominent nasal bridge (HP:0000426)1.71150468
87Hyperphosphatemia (HP:0002905)1.70539094
88Abnormality of renal excretion (HP:0011036)1.69914807
89Aplasia/Hypoplasia of the tongue (HP:0010295)1.67135461
90Microglossia (HP:0000171)1.65510216
91Cystic liver disease (HP:0006706)1.65066270
92Multicystic kidney dysplasia (HP:0000003)1.62460509
93Aganglionic megacolon (HP:0002251)1.60889587
94Broad foot (HP:0001769)1.59666362
95Hyperglycinemia (HP:0002154)1.59507372
96Oculomotor apraxia (HP:0000657)1.59325344
97Absent epiphyses (HP:0010577)1.57957488
98Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.57957488
99Gaze-evoked nystagmus (HP:0000640)1.55659723
100Constricted visual fields (HP:0001133)1.55488478
101Atelectasis (HP:0100750)1.55390567
102Nephropathy (HP:0000112)1.55248067
103Cone-rod dystrophy (HP:0000548)1.54888487
104Deformed sella turcica (HP:0002681)1.53791522
105Aplasia/Hypoplasia of the fibula (HP:0006492)1.53664199
106Specific learning disability (HP:0001328)1.52815713
107Insulin-resistant diabetes mellitus (HP:0000831)1.52496864
108Narrow forehead (HP:0000341)1.50714656
109Short femoral neck (HP:0100864)1.50367483
110Absent eyebrow (HP:0002223)1.50302347
111Cardiovascular calcification (HP:0011915)1.50242318
112Short ribs (HP:0000773)1.49768135
113Genital tract atresia (HP:0001827)1.48541065
114Bell-shaped thorax (HP:0001591)1.48067320
115Central scotoma (HP:0000603)1.47183239
116Pancreatic cysts (HP:0001737)1.44364401
117Short thorax (HP:0010306)1.44222107
118Retinal dysplasia (HP:0007973)1.43869224
119Amyotrophic lateral sclerosis (HP:0007354)1.43071920
120Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.40746640
121Sloping forehead (HP:0000340)1.40584712
122Vaginal atresia (HP:0000148)1.40489768
123Poor coordination (HP:0002370)1.40346196
124Polyuria (HP:0000103)1.39777979
125Asthma (HP:0002099)1.38188521
126Absent speech (HP:0001344)1.38065702
127Decreased circulating renin level (HP:0003351)1.37869294
128Aplasia/Hypoplasia of the tibia (HP:0005772)1.37727460
129Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.37595136
130Hyperkalemia (HP:0002153)1.37284990
131Ectopic kidney (HP:0000086)1.37076327
132Upper motor neuron abnormality (HP:0002127)1.36931248
133Decreased testicular size (HP:0008734)1.36381600
134Left ventricular hypertrophy (HP:0001712)1.36202842
135Abnormality of renal resorption (HP:0011038)1.35570869
136Short nail (HP:0001799)1.34901475
137Abnormality of dentin (HP:0010299)1.34784825
138Astigmatism (HP:0000483)1.33286395
139Menstrual irregularities (HP:0000858)1.30513930
140Aplasia/Hypoplasia of the spleen (HP:0010451)1.30502484
141Hypothermia (HP:0002045)1.28786448
142Highly arched eyebrow (HP:0002553)1.28537178
143Hyperaldosteronism (HP:0000859)1.26874122

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.48829549
2PDK38.48829549
3PDK25.72355223
4TESK14.19022502
5TLK13.96355896
6MST43.64198402
7PRKD33.33039237
8FRK3.09567396
9ICK2.56729434
10LATS12.51471754
11PTK2B2.23675629
12BCR2.21028271
13CASK1.88871243
14WNK41.70851300
15PNCK1.64866904
16STK391.62303992
17YES11.58200483
18MUSK1.54629081
19SIK31.48840724
20MAPK151.44231749
21MARK11.41379054
22STK381.37702911
23CSNK1A1L1.36280359
24CDC71.28389458
25PLK21.24924642
26CSNK1G31.19159369
27CSNK1G11.12340396
28CSNK1G21.09600563
29PHKG21.07618082
30PHKG11.07618082
31DYRK1B1.07601060
32STK38L1.06863524
33PLK11.06795963
34NEK21.05929248
35NUAK11.05807409
36BRSK21.00783538
37BMPR1B0.98346517
38IRAK10.95976797
39PINK10.95061775
40MET0.91243191
41TXK0.90489877
42EPHA20.90310076
43WNK10.85811771
44RIPK40.84770201
45TRIM280.83260363
46STK240.80109779
47ZAK0.74024188
48PDK10.72394137
49MAP2K70.70385543
50STK30.70186591
51BRD40.68785540
52PRKCI0.68386377
53AKT30.68308730
54AURKA0.67007671
55MAP3K120.66244649
56CCNB10.65988359
57INSRR0.63181369
58MST1R0.62301875
59RPS6KA40.61660202
60ACVR1B0.61171848
61RPS6KA50.59664761
62CDK80.59292129
63MAP3K140.58607699
64OXSR10.57920850
65PRKCE0.57858288
66CDK30.57548959
67PRPF4B0.56334657
68MAP4K20.55875897
69PASK0.55344649
70DYRK20.54657979
71PAK30.54369082
72NEK60.52481600
73MYLK0.52402579
74ADRBK20.50497923
75LIMK10.50371949
76ADRBK10.50112783
77NTRK20.49985629
78CHEK20.49567752
79TNIK0.49502191
80EIF2AK30.46967066
81SGK20.46896131
82TTK0.46806706
83ATR0.46719948
84BUB10.42855509
85NME10.42614494
86PRKCG0.42495965
87TEC0.42105880
88PLK40.41984076
89SRPK10.40217193
90VRK10.40181046
91TYRO30.39799392
92ROCK10.37499525
93DYRK30.37154796
94MAP2K60.36819547
95PLK30.35449246
96TIE10.35041307
97LMTK20.34685286
98SIK20.34497024
99MARK20.34435409
100EIF2AK20.34152098
101MARK30.33570768
102CAMK2G0.33490847
103RPS6KB10.32844938
104IRAK20.31753117
105ATM0.31366477
106CHEK10.30999347
107OBSCN0.29376489
108PKN10.28134686
109ERBB30.24318904
110BRAF0.23600277
111WNK30.22450026
112CAMK2A0.22264719
113GRK10.22116056
114CAMK10.21815307
115BMPR20.21706542
116PRKG10.21615288
117EIF2AK10.20714444
118PRKAA10.19600483
119WEE10.19558758
120GRK70.18127217
121MAPK100.17378867
122PBK0.17262274
123MAPK130.17122056
124TNK20.16924358
125IRAK30.15999994
126NTRK30.15739754
127PIM10.15604675
128CSK0.15509167
129HCK0.14765615
130MKNK20.14593993
131MAPK40.14314426
132SGK4940.14206541
133SGK2230.14206541
134PDPK10.14084523
135MAPK80.13298412
136PRKCA0.12710084
137STK160.11952534
138MAPKAPK50.11877703
139CAMK1G0.10488773
140MAP3K40.10481511
141EPHA40.10199778
142PRKCD0.10035394
143PRKCZ0.09431877
144PAK10.09276592
145LYN0.08850405
146GSK3B0.08448131

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.06838359
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.65190927
3Basal transcription factors_Homo sapiens_hsa030223.11342561
4Fatty acid biosynthesis_Homo sapiens_hsa000612.89195952
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.86539663
6Fanconi anemia pathway_Homo sapiens_hsa034602.82810851
7Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.79390955
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.71623141
9Butanoate metabolism_Homo sapiens_hsa006502.69555133
10Pyruvate metabolism_Homo sapiens_hsa006202.66246090
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.42302584
12Linoleic acid metabolism_Homo sapiens_hsa005912.23186481
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.22662578
14beta-Alanine metabolism_Homo sapiens_hsa004102.12077366
15Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.09489422
16Glucagon signaling pathway_Homo sapiens_hsa049222.02083276
17Glutathione metabolism_Homo sapiens_hsa004801.97552387
18Propanoate metabolism_Homo sapiens_hsa006401.93106010
19Nicotine addiction_Homo sapiens_hsa050331.88331636
20Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.87655377
21Dorso-ventral axis formation_Homo sapiens_hsa043201.83543844
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.74890572
23Histidine metabolism_Homo sapiens_hsa003401.74721133
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.70744232
25Selenocompound metabolism_Homo sapiens_hsa004501.66983890
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.65661142
27Peroxisome_Homo sapiens_hsa041461.57687697
28Glycosaminoglycan degradation_Homo sapiens_hsa005311.57592436
29Circadian rhythm_Homo sapiens_hsa047101.56478183
30Huntingtons disease_Homo sapiens_hsa050161.48729996
31Mineral absorption_Homo sapiens_hsa049781.47996569
32Phenylalanine metabolism_Homo sapiens_hsa003601.44581556
33Glycerolipid metabolism_Homo sapiens_hsa005611.43761745
34Amphetamine addiction_Homo sapiens_hsa050311.38107989
35Protein export_Homo sapiens_hsa030601.37997586
36Carbohydrate digestion and absorption_Homo sapiens_hsa049731.33871101
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.33002387
38Tyrosine metabolism_Homo sapiens_hsa003501.32905962
39Arachidonic acid metabolism_Homo sapiens_hsa005901.29889862
40Fatty acid degradation_Homo sapiens_hsa000711.29213330
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29133197
42Pentose phosphate pathway_Homo sapiens_hsa000301.25926484
43Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.24387054
44Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.21701581
45Ether lipid metabolism_Homo sapiens_hsa005651.19349822
46Oxidative phosphorylation_Homo sapiens_hsa001901.18112635
47Mismatch repair_Homo sapiens_hsa034301.15178637
48Synaptic vesicle cycle_Homo sapiens_hsa047211.14629111
49Taste transduction_Homo sapiens_hsa047421.14335822
50Nitrogen metabolism_Homo sapiens_hsa009101.13999779
51Steroid biosynthesis_Homo sapiens_hsa001001.12018834
52One carbon pool by folate_Homo sapiens_hsa006701.11178264
53Collecting duct acid secretion_Homo sapiens_hsa049661.11035320
54Primary bile acid biosynthesis_Homo sapiens_hsa001201.09951417
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.06686302
56Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.06349218
57Renin secretion_Homo sapiens_hsa049241.02217990
58Graft-versus-host disease_Homo sapiens_hsa053321.01720473
59Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.00622020
60Tryptophan metabolism_Homo sapiens_hsa003801.00226049
61Calcium signaling pathway_Homo sapiens_hsa040200.99543557
62Parkinsons disease_Homo sapiens_hsa050120.99152319
63Purine metabolism_Homo sapiens_hsa002300.97200309
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.97011820
65Oocyte meiosis_Homo sapiens_hsa041140.95585316
66Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.94603353
67Phototransduction_Homo sapiens_hsa047440.93803544
68Rheumatoid arthritis_Homo sapiens_hsa053230.93277080
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93032013
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.91363267
71PPAR signaling pathway_Homo sapiens_hsa033200.91199466
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.91198117
73Legionellosis_Homo sapiens_hsa051340.90595291
74Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.89793705
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.87455596
76Non-homologous end-joining_Homo sapiens_hsa034500.87399483
77Nucleotide excision repair_Homo sapiens_hsa034200.85984125
78Olfactory transduction_Homo sapiens_hsa047400.85674350
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.80435443
80Regulation of autophagy_Homo sapiens_hsa041400.79085194
81Lysine degradation_Homo sapiens_hsa003100.78263015
82Inositol phosphate metabolism_Homo sapiens_hsa005620.77601277
83Measles_Homo sapiens_hsa051620.76807127
84Glutamatergic synapse_Homo sapiens_hsa047240.75904910
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.75724369
86Arginine and proline metabolism_Homo sapiens_hsa003300.75635151
87Fructose and mannose metabolism_Homo sapiens_hsa000510.75249033
88ABC transporters_Homo sapiens_hsa020100.75135351
89Antigen processing and presentation_Homo sapiens_hsa046120.74298227
90Sphingolipid metabolism_Homo sapiens_hsa006000.74012913
91Maturity onset diabetes of the young_Homo sapiens_hsa049500.73917932
92Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.72625341
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.72283508
94Ovarian steroidogenesis_Homo sapiens_hsa049130.70730508
95Alcoholism_Homo sapiens_hsa050340.68743385
96RNA transport_Homo sapiens_hsa030130.68498354
97Hippo signaling pathway_Homo sapiens_hsa043900.67734191
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67592571
99Cell cycle_Homo sapiens_hsa041100.66619054
100Insulin secretion_Homo sapiens_hsa049110.66002148
101Herpes simplex infection_Homo sapiens_hsa051680.65382743
102Basal cell carcinoma_Homo sapiens_hsa052170.65229770
103Morphine addiction_Homo sapiens_hsa050320.64948106
104Alzheimers disease_Homo sapiens_hsa050100.64874808
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.63881354
106Circadian entrainment_Homo sapiens_hsa047130.63270517
107Tight junction_Homo sapiens_hsa045300.63247270
108Folate biosynthesis_Homo sapiens_hsa007900.62785221
109Phagosome_Homo sapiens_hsa041450.61048863
110Gap junction_Homo sapiens_hsa045400.57821662
111Steroid hormone biosynthesis_Homo sapiens_hsa001400.57322933
112Cardiac muscle contraction_Homo sapiens_hsa042600.57138121
113Base excision repair_Homo sapiens_hsa034100.56948544
114Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56737181
115Allograft rejection_Homo sapiens_hsa053300.55869878
116Fat digestion and absorption_Homo sapiens_hsa049750.55308253
117Pyrimidine metabolism_Homo sapiens_hsa002400.54948375
118Salmonella infection_Homo sapiens_hsa051320.53377253
119Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52142775
120Homologous recombination_Homo sapiens_hsa034400.50857280
121Fatty acid elongation_Homo sapiens_hsa000620.49124588
122DNA replication_Homo sapiens_hsa030300.48878039
123RNA polymerase_Homo sapiens_hsa030200.48768803
124Influenza A_Homo sapiens_hsa051640.48613833
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.48562286
126Long-term potentiation_Homo sapiens_hsa047200.47508643
127RNA degradation_Homo sapiens_hsa030180.47112027
128Vitamin digestion and absorption_Homo sapiens_hsa049770.46616950
129Caffeine metabolism_Homo sapiens_hsa002320.45964703
130Cysteine and methionine metabolism_Homo sapiens_hsa002700.45839387
131Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45370039
132Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.45275595
133Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43621229
134mRNA surveillance pathway_Homo sapiens_hsa030150.43206269
135Retinol metabolism_Homo sapiens_hsa008300.42599156
136SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41681436
137p53 signaling pathway_Homo sapiens_hsa041150.41257003
138Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40884856
139Autoimmune thyroid disease_Homo sapiens_hsa053200.40875581
140Tuberculosis_Homo sapiens_hsa051520.40564423
141Wnt signaling pathway_Homo sapiens_hsa043100.39089472
142Serotonergic synapse_Homo sapiens_hsa047260.38993343
143Malaria_Homo sapiens_hsa051440.37864451
144Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.37824217
145Chemical carcinogenesis_Homo sapiens_hsa052040.37590601
146Hematopoietic cell lineage_Homo sapiens_hsa046400.37500623
147Asthma_Homo sapiens_hsa053100.36771587
148Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35962073
149cAMP signaling pathway_Homo sapiens_hsa040240.35495674
150Type I diabetes mellitus_Homo sapiens_hsa049400.34203651
151Metabolic pathways_Homo sapiens_hsa011000.32192192
152cGMP-PKG signaling pathway_Homo sapiens_hsa040220.30770854
153Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30749559
154Hedgehog signaling pathway_Homo sapiens_hsa043400.29138365
155Renin-angiotensin system_Homo sapiens_hsa046140.28834532
156Fatty acid metabolism_Homo sapiens_hsa012120.28614480
157Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28273172
158Salivary secretion_Homo sapiens_hsa049700.26641649

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