IQCD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.95369219
2acrosome assembly (GO:0001675)9.53735258
3binding of sperm to zona pellucida (GO:0007339)9.30067177
4multicellular organism reproduction (GO:0032504)9.14167264
5regulation of cilium movement (GO:0003352)9.09910645
6cell-cell recognition (GO:0009988)8.91282618
7cell wall macromolecule catabolic process (GO:0016998)8.62468845
8cell wall macromolecule metabolic process (GO:0044036)8.62468845
9spermatid development (GO:0007286)8.59627038
10plasma membrane fusion (GO:0045026)8.33519850
11piRNA metabolic process (GO:0034587)8.16457902
12reproduction (GO:0000003)7.61982610
13male meiosis (GO:0007140)7.44472629
14synaptonemal complex organization (GO:0070193)7.06376241
15single fertilization (GO:0007338)6.82274592
16synaptonemal complex assembly (GO:0007130)6.58731243
17ventricular system development (GO:0021591)6.50257154
18negative regulation of inclusion body assembly (GO:0090084)6.41892663
19sperm capacitation (GO:0048240)5.99316864
20male meiosis I (GO:0007141)5.82218145
21fertilization (GO:0009566)5.81130694
22primary alcohol catabolic process (GO:0034310)5.79452360
23spermatogenesis (GO:0007283)5.76632049
24male gamete generation (GO:0048232)5.74270891
25axoneme assembly (GO:0035082)5.45399224
26regulation of microtubule-based movement (GO:0060632)5.41440169
27microtubule severing (GO:0051013)5.38439582
28vitamin transmembrane transport (GO:0035461)5.30496925
29gamete generation (GO:0007276)5.26601609
30regulation of inclusion body assembly (GO:0090083)5.25573126
31DNA methylation involved in gamete generation (GO:0043046)5.12950414
32organic cation transport (GO:0015695)4.96719890
33protein localization to cilium (GO:0061512)4.93784144
34diterpenoid biosynthetic process (GO:0016102)4.84539528
35germ cell development (GO:0007281)4.82901658
36protein polyglutamylation (GO:0018095)4.81914299
37meiosis I (GO:0007127)4.81639582
38negative regulation of T cell differentiation in thymus (GO:0033085)4.76467313
39intraciliary transport (GO:0042073)4.70826749
40cellular process involved in reproduction in multicellular organism (GO:0022412)4.69486708
41microtubule depolymerization (GO:0007019)4.67638952
42calcium ion-dependent exocytosis (GO:0017156)4.55031722
43meiotic nuclear division (GO:0007126)4.52811510
44nucleoside diphosphate phosphorylation (GO:0006165)4.50038416
45chromosome organization involved in meiosis (GO:0070192)4.49373958
46centriole assembly (GO:0098534)4.48385945
47ethanol metabolic process (GO:0006067)4.47113250
48left/right pattern formation (GO:0060972)4.45981934
49cell recognition (GO:0008037)4.38971070
50lung epithelium development (GO:0060428)4.38757428
51meiotic cell cycle (GO:0051321)4.17341338
52cilium organization (GO:0044782)4.16110175
53multicellular organismal reproductive process (GO:0048609)4.15148403
54response to xenobiotic stimulus (GO:0009410)4.12942036
55seminiferous tubule development (GO:0072520)4.10513884
56pyrimidine-containing compound transmembrane transport (GO:0072531)4.09206547
57chaperone-mediated protein complex assembly (GO:0051131)4.08883844
58cilium assembly (GO:0042384)3.96509230
59glomerular epithelial cell development (GO:0072310)3.91391044
60microtubule polymerization or depolymerization (GO:0031109)3.90336996
61cilium morphogenesis (GO:0060271)3.87312717
62GTP biosynthetic process (GO:0006183)3.83652209
63tolerance induction (GO:0002507)3.82096042
64microtubule-based movement (GO:0007018)3.72848191
65establishment of apical/basal cell polarity (GO:0035089)3.72327315
66one-carbon compound transport (GO:0019755)3.71971556
67centriole replication (GO:0007099)3.66479829
68chromosome condensation (GO:0030261)3.65853219
69spermatid nucleus differentiation (GO:0007289)3.64943389
70nonmotile primary cilium assembly (GO:0035058)3.58849887
71terpenoid biosynthetic process (GO:0016114)3.58418629
72UTP biosynthetic process (GO:0006228)3.53611793
73DNA packaging (GO:0006323)3.50971586
74determination of left/right symmetry (GO:0007368)3.47464911
75cellular component assembly involved in morphogenesis (GO:0010927)3.46962510
76establishment or maintenance of monopolar cell polarity (GO:0061339)3.37758949
77establishment of monopolar cell polarity (GO:0061162)3.37758949
78retinoic acid metabolic process (GO:0042573)3.36492005
79negative regulation of immunoglobulin mediated immune response (GO:0002890)3.35248121
80negative regulation of B cell mediated immunity (GO:0002713)3.35248121
81smoothened signaling pathway (GO:0007224)3.32031385
82determination of bilateral symmetry (GO:0009855)3.30778434
83glycerol ether metabolic process (GO:0006662)3.30338710
84lateral ventricle development (GO:0021670)3.30060108
85genitalia morphogenesis (GO:0035112)3.28216103
86protein refolding (GO:0042026)3.25865922
87specification of symmetry (GO:0009799)3.25685755
88cytoplasmic microtubule organization (GO:0031122)3.24995315
89UTP metabolic process (GO:0046051)3.24676912
90ethanol oxidation (GO:0006069)3.24581597
91multicellular organismal development (GO:0007275)3.22817644
92establishment of tissue polarity (GO:0007164)3.22390043
93establishment of planar polarity (GO:0001736)3.22390043
94calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.22012145
95glutathione derivative biosynthetic process (GO:1901687)3.21782683
96glutathione derivative metabolic process (GO:1901685)3.21782683
97regulation of interleukin-5 production (GO:0032674)3.15530086
98intra-S DNA damage checkpoint (GO:0031573)3.08469076
99lateral sprouting from an epithelium (GO:0060601)3.07069778
100left/right axis specification (GO:0070986)3.07036312
101gene silencing by RNA (GO:0031047)3.03800190
102microtubule-based process (GO:0007017)3.02756677
103glycolytic process (GO:0006096)3.02405777
104ether metabolic process (GO:0018904)3.01389631
105negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.97248822
106microtubule bundle formation (GO:0001578)2.95611040
107positive regulation of tolerance induction (GO:0002645)2.94949425
108aldehyde catabolic process (GO:0046185)2.94766131
109meiotic cell cycle process (GO:1903046)2.93494950
110regulation of centriole replication (GO:0046599)2.93372564
111negative regulation of humoral immune response (GO:0002921)2.92987257
112negative regulation of organelle assembly (GO:1902116)2.91832807
113retinol metabolic process (GO:0042572)2.89934409
114single strand break repair (GO:0000012)2.87605167
115ADP metabolic process (GO:0046031)2.83308473
116guanosine-containing compound biosynthetic process (GO:1901070)2.82409979
117cornea development in camera-type eye (GO:0061303)2.78728062
118peptidyl-glutamic acid modification (GO:0018200)2.78290862
119positive regulation of gastrulation (GO:2000543)2.78267815
120ear development (GO:0043583)2.76545515
121interferon-gamma secretion (GO:0072643)2.75915079
122organelle assembly (GO:0070925)2.75034277
123positive regulation of smoothened signaling pathway (GO:0045880)2.71397490
124regulation of response to osmotic stress (GO:0047484)2.70345652
125regulation of spindle checkpoint (GO:0090231)2.70096194
126neurotransmitter catabolic process (GO:0042135)2.67971205
127primary alcohol metabolic process (GO:0034308)2.66970866
128regulation of interleukin-13 production (GO:0032656)2.66499487
129lactate metabolic process (GO:0006089)2.63299904
130exogenous drug catabolic process (GO:0042738)2.62974348
131embryonic camera-type eye development (GO:0031076)2.62477387
132CTP biosynthetic process (GO:0006241)2.61482429
133CTP metabolic process (GO:0046036)2.61482429
134regulation of microtubule depolymerization (GO:0031114)2.61159127
135excretion (GO:0007588)2.60831557
136heart looping (GO:0001947)2.56954241
137regulation of meiosis I (GO:0060631)2.56144450
138regulation of germinal center formation (GO:0002634)2.55694006
139amino-acid betaine transport (GO:0015838)2.53006423
140carnitine transport (GO:0015879)2.53006423
141nucleus organization (GO:0006997)2.52572261
142synapsis (GO:0007129)2.51999591
143regulation of chromatin binding (GO:0035561)2.51926160
144cell projection assembly (GO:0030031)2.51439310
145nucleotide phosphorylation (GO:0046939)2.51095633
146nuclear pore complex assembly (GO:0051292)2.50017871
147hydrogen peroxide biosynthetic process (GO:0050665)2.46484638
148embryonic body morphogenesis (GO:0010172)2.45851487
149O-glycan processing (GO:0016266)2.44880500
150photoreceptor cell maintenance (GO:0045494)2.43476862
151regulation of collateral sprouting (GO:0048670)2.40484332
152regulation of smoothened signaling pathway (GO:0008589)2.40039727
153embryonic heart tube morphogenesis (GO:0003143)2.37765569
154nucleoside diphosphate metabolic process (GO:0009132)2.37290978
155retinal rod cell development (GO:0046548)2.36183674
156retinal cone cell development (GO:0046549)2.33543071
157regulation of autophagic vacuole assembly (GO:2000785)2.27904014
158apical protein localization (GO:0045176)2.27361759
159carnitine metabolic process (GO:0009437)2.24778317
160cilium or flagellum-dependent cell motility (GO:0001539)13.9078828
161axonemal dynein complex assembly (GO:0070286)12.4703691
162sperm motility (GO:0030317)11.9423109
163epithelial cilium movement (GO:0003351)11.1804336
164fusion of sperm to egg plasma membrane (GO:0007342)11.1037537
165motile cilium assembly (GO:0044458)10.7243041
166cilium movement (GO:0003341)10.4923571
167acrosome reaction (GO:0007340)10.3697239
168epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.3683100

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.87695261
2EZH2_22144423_ChIP-Seq_EOC_Human4.97538906
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.49552972
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.41911438
5TRIM28_21343339_ChIP-Seq_HEK293_Human3.53012901
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.44895345
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.22342887
8FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.16131820
9GATA1_26923725_Chip-Seq_HPCs_Mouse3.03064158
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.73938253
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.40233181
12DROSHA_22980978_ChIP-Seq_HELA_Human2.30699179
13CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.25422290
14ZNF274_21170338_ChIP-Seq_K562_Hela2.09457113
15VDR_22108803_ChIP-Seq_LS180_Human2.00764138
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.1860095
17* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.98588341
18ELK4_26923725_Chip-Seq_MESODERM_Mouse1.90284141
19ESR1_21235772_ChIP-Seq_MCF-7_Human1.85461146
20CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.77777770
21WDR5_24793694_ChIP-Seq_LNCAP_Human1.76174651
22RUNX1_27514584_Chip-Seq_MCF-7_Human1.75350818
23* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.72723485
24ESR1_20079471_ChIP-ChIP_T-47D_Human1.71642216
25FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.69082861
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.68742397
27FOXM1_26456572_ChIP-Seq_MCF-7_Human1.68583467
28SOX2_22085726_ChIP-Seq_NPCs_Mouse1.65274237
29AHR_22903824_ChIP-Seq_MCF-7_Human1.61208537
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.58477140
31ESR2_21235772_ChIP-Seq_MCF-7_Human1.58355553
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54641595
33CDX2_20551321_ChIP-Seq_CACO-2_Human1.50818650
34EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.49280969
35KLF5_25053715_ChIP-Seq_YYC3_Human1.47645596
36MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.47185951
37FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46886410
38STAT1_17558387_ChIP-Seq_HELA_Human1.45782616
39ARNT_22903824_ChIP-Seq_MCF-7_Human1.45683448
40IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44378659
41CBP_20019798_ChIP-Seq_JUKART_Human1.44378659
42TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.43884857
43YY1_22570637_ChIP-Seq_MALME-3M_Human1.42634466
44* GATA3_21867929_ChIP-Seq_CD8_Mouse1.39949658
45FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.38114953
46TAL1_26923725_Chip-Seq_HPCs_Mouse1.37923646
47TDRD3_21172665_ChIP-Seq_MCF-7_Human1.36832454
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.36117711
49REST_21632747_ChIP-Seq_MESCs_Mouse1.35585202
50PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.34931021
51KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.34778345
52NR3C1_21868756_ChIP-Seq_MCF10A_Human1.33212590
53P53_21459846_ChIP-Seq_SAOS-2_Human1.33008107
54GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.32358560
55CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31643604
56SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.31029696
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.30234826
58LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.29232612
59GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26989515
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26877336
61* RAD21_21589869_ChIP-Seq_MESCs_Mouse1.26466829
62ERG_20517297_ChIP-Seq_VCAP_Human1.26258781
63CTCF_20526341_ChIP-Seq_ESCs_Human1.25281676
64FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24707040
65EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.23884228
66ELF1_20517297_ChIP-Seq_JURKAT_Human1.23168092
67TP63_23658742_ChIP-Seq_EP156T_Human1.20455896
68FOXA1_25552417_ChIP-Seq_VCAP_Human1.19802538
69LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19632253
70BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19454985
71MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16882117
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.16870285
73ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16309847
74* TP63_22573176_ChIP-Seq_HFKS_Human1.15778127
75SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.15721038
76SOX2_20726797_ChIP-Seq_SW620_Human1.15653465
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.15540778
78PHF8_20622853_ChIP-Seq_HELA_Human1.15392873
79SMRT_27268052_Chip-Seq_Bcells_Human1.15067189
80ETV1_20927104_ChIP-Seq_GIST48_Human1.14986363
81TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14548494
82STAT6_21828071_ChIP-Seq_BEAS2B_Human1.14256238
83* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13450063
84KAP1_22055183_ChIP-Seq_ESCs_Mouse1.13133725
85SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11939760
86SOX2_27498859_Chip-Seq_STOMACH_Mouse1.10811237
87RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.10598821
88EZH2_27294783_Chip-Seq_ESCs_Mouse1.10445751
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10442981
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10442981
91GATA3_21867929_ChIP-Seq_TH1_Mouse1.08166407
92CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.07919253
93TP53_18474530_ChIP-ChIP_U2OS_Human1.07612658
94SPI1_26923725_Chip-Seq_HPCs_Mouse1.06390593
95PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.05501608
96RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.05046636
97MYC_27129775_Chip-Seq_CORNEA_Mouse1.04529126
98KDM2B_26808549_Chip-Seq_REH_Human1.04209620
99RBPJ_21746931_ChIP-Seq_IB4_Human1.04093620
100RBPJ_22232070_ChIP-Seq_NCS_Mouse1.03933677
101ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.02923465
102GATA4_25053715_ChIP-Seq_YYC3_Human1.02916129
103P68_20966046_ChIP-Seq_HELA_Human1.02768116
104PHF8_20622854_ChIP-Seq_HELA_Human1.02691391
105BCOR_27268052_Chip-Seq_Bcells_Human1.02372177
106SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.01522241
107E2F1_17053090_ChIP-ChIP_MCF-7_Human1.01313424
108CBP_21632823_ChIP-Seq_H3396_Human1.00699019
109RUNX1_26923725_Chip-Seq_HPCs_Mouse1.00078807
110* GATA3_24758297_ChIP-Seq_MCF-7_Human0.99324694
111RARA_24833708_ChIP-Seq_LIVER_Mouse0.99274766
112CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99073781
113NCOR_22424771_ChIP-Seq_293T_Human0.98407508
114PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97518309
115FLI1_21867929_ChIP-Seq_CD8_Mouse0.97472091
116CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97096199
117CTCF_27219007_Chip-Seq_Bcells_Human0.96976375
118FLI1_21867929_ChIP-Seq_TH2_Mouse0.96896051
119EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95919077
120GF1_26923725_Chip-Seq_HPCs_Mouse0.95807054
121GATA1_19941827_ChIP-Seq_MEL86_Mouse0.95139072
122SMC4_20622854_ChIP-Seq_HELA_Human0.95052592
123AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.94888036
124* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94709321
125AR_20517297_ChIP-Seq_VCAP_Human0.94593538
126TET1_21451524_ChIP-Seq_MESCs_Mouse0.94231896
127NANOG_20526341_ChIP-Seq_ESCs_Human0.93410779
128SOX2_21211035_ChIP-Seq_LN229_Human0.93210243
129GATA6_21074721_ChIP-Seq_CACO-2_Human0.92050218
130CEBPB_22108803_ChIP-Seq_LS180_Human0.91504115
131PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91276600
132E2F1_20622854_ChIP-Seq_HELA_Human0.91022633
133SMC3_22415368_ChIP-Seq_MEFs_Mouse0.90964725
134ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.90565232
135STAT1_20625510_ChIP-Seq_HELA_Human0.90524886
136HNFA_21074721_ChIP-Seq_CACO-2_Human0.90462621
137RXRA_24833708_ChIP-Seq_LIVER_Mouse0.90183304
138RNF2_27304074_Chip-Seq_NSC_Mouse0.89914555
139GABP_17652178_ChIP-ChIP_JURKAT_Human0.89737909
140P300_27268052_Chip-Seq_Bcells_Human0.88935731
141EWS_26573619_Chip-Seq_HEK293_Human0.88859916
142PCGF2_27294783_Chip-Seq_NPCs_Mouse0.88693608
143RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.88157538
144P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.88003822
145* TCF4_22108803_ChIP-Seq_LS180_Human0.87250539
146* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86914792
147GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.86746244
148KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.86360645
149MYC_19829295_ChIP-Seq_ESCs_Human0.86103737
150FOXA1_25329375_ChIP-Seq_VCAP_Human0.85870664
151FOXA1_27270436_Chip-Seq_PROSTATE_Human0.85870664
152TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.85463949
153SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.84952716
154ZNF217_24962896_ChIP-Seq_MCF-7_Human0.84624602
155CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84584839
156NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.84519390
157PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84264312
158FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.84221706
159NFE2_27457419_Chip-Seq_LIVER_Mouse0.83961820
160CREB1_26743006_Chip-Seq_LNCaP_Human0.83434622
161STAT3_1855785_ChIP-Seq_MESCs_Mouse0.83211467
162NFYA_21822215_ChIP-Seq_K562_Human0.83075886
163PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.83046956
164TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.82628661
165SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82272212
166ETV2_25802403_ChIP-Seq_MESCs_Mouse0.82264042
167SOX11_22085726_ChIP-Seq_ESNs_Mouse0.81988074
168SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.80497600
169CTBP2_25329375_ChIP-Seq_LNCAP_Human0.79989882

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.62660688
2MP0008875_abnormal_xenobiotic_pharmacok5.08319905
3MP0001929_abnormal_gametogenesis5.02004245
4MP0002653_abnormal_ependyma_morphology4.50317471
5MP0000566_synostosis4.29200248
6MP0008877_abnormal_DNA_methylation4.11339001
7MP0001984_abnormal_olfaction3.71822392
8MP0010030_abnormal_orbit_morphology3.47412347
9MP0002210_abnormal_sex_determination3.32202635
10MP0002161_abnormal_fertility/fecundity3.09395528
11MP0002277_abnormal_respiratory_mucosa3.04760266
12MP0001145_abnormal_male_reproductive2.79549597
13MP0005623_abnormal_meninges_morphology2.45877674
14MP0000653_abnormal_sex_gland2.37413352
15MP0009379_abnormal_foot_pigmentation2.28220911
16MP0001346_abnormal_lacrimal_gland2.27195050
17MP0002160_abnormal_reproductive_system2.15233199
18MP0009780_abnormal_chondrocyte_physiolo2.07936164
19MP0005670_abnormal_white_adipose2.00263521
20MP0006292_abnormal_olfactory_placode2.00034062
21MP0005410_abnormal_fertilization14.2242640
22MP0000383_abnormal_hair_follicle1.84943121
23MP0005083_abnormal_biliary_tract1.69301179
24MP0003011_delayed_dark_adaptation1.61549522
25MP0005248_abnormal_Harderian_gland1.57321335
26MP0003718_maternal_effect1.55249582
27MP0003938_abnormal_ear_development1.53857988
28MP0010678_abnormal_skin_adnexa1.51191536
29MP0002282_abnormal_trachea_morphology1.50426677
30MP0002249_abnormal_larynx_morphology1.39264742
31MP0002233_abnormal_nose_morphology1.36172451
32MP0000049_abnormal_middle_ear1.34548038
33MP0005551_abnormal_eye_electrophysiolog1.30193007
34MP0000026_abnormal_inner_ear1.19641445
35MP0005389_reproductive_system_phenotype1.19115953
36MP0002928_abnormal_bile_duct1.18339963
37MP0003890_abnormal_embryonic-extraembry1.18192870
38MP0005408_hypopigmentation1.13863627
39MP0009046_muscle_twitch1.11857445
40MP0000678_abnormal_parathyroid_gland1.09417338
41MP0001849_ear_inflammation1.06811508
42MP0005647_abnormal_sex_gland1.05274510
43MP0002638_abnormal_pupillary_reflex1.04939599
44MP0003878_abnormal_ear_physiology1.04514468
45MP0005377_hearing/vestibular/ear_phenot1.04514468
46MP0005395_other_phenotype1.02913779
47MP0003646_muscle_fatigue0.99643370
48MP0002822_catalepsy0.96812131
49MP0008058_abnormal_DNA_repair0.93239626
50MP0003186_abnormal_redox_activity0.92704726
51MP0003136_yellow_coat_color0.90833579
52MP0002098_abnormal_vibrissa_morphology0.90408573
53MP0001765_abnormal_ion_homeostasis0.89087665
54MP0002734_abnormal_mechanical_nocicepti0.88988503
55MP0005253_abnormal_eye_physiology0.88836416
56MP0000631_abnormal_neuroendocrine_gland0.88494713
57MP0001286_abnormal_eye_development0.83729629
58MP0009384_cardiac_valve_regurgitation0.83303835
59MP0003937_abnormal_limbs/digits/tail_de0.83114232
60MP0010094_abnormal_chromosome_stability0.82766889
61MP0001545_abnormal_hematopoietic_system0.81822767
62MP0005397_hematopoietic_system_phenotyp0.81822767
63MP0005645_abnormal_hypothalamus_physiol0.80375308
64MP0002234_abnormal_pharynx_morphology0.78848549
65MP0008057_abnormal_DNA_replication0.78261470
66MP0005171_absent_coat_pigmentation0.78102703
67MP0000681_abnormal_thyroid_gland0.77692735
68MP0004133_heterotaxia0.77142638
69MP0001188_hyperpigmentation0.76681727
70MP0008789_abnormal_olfactory_epithelium0.76093851
71MP0005394_taste/olfaction_phenotype0.76003619
72MP0005499_abnormal_olfactory_system0.76003619
73MP0001270_distended_abdomen0.73124728
74MP0002168_other_aberrant_phenotype0.73123976
75MP0005084_abnormal_gallbladder_morpholo0.72410130
76MP0003111_abnormal_nucleus_morphology0.72020328
77MP0002116_abnormal_craniofacial_bone0.71004374
78MP0008007_abnormal_cellular_replicative0.70079297
79MP0005391_vision/eye_phenotype0.67335836
80MP0000647_abnormal_sebaceous_gland0.66850830
81MP0005195_abnormal_posterior_eye0.66844473
82MP0003705_abnormal_hypodermis_morpholog0.66605308
83MP0004885_abnormal_endolymph0.66493737
84MP0002938_white_spotting0.66375378
85MP0003115_abnormal_respiratory_system0.66221181
86MP0005167_abnormal_blood-brain_barrier0.65431014
87MP0000955_abnormal_spinal_cord0.63939321
88MP0004233_abnormal_muscle_weight0.63874518
89MP0005646_abnormal_pituitary_gland0.61151678
90MP0003879_abnormal_hair_cell0.60604152
91MP0009115_abnormal_fat_cell0.60430190
92MP0000537_abnormal_urethra_morphology0.60237261
93MP0001944_abnormal_pancreas_morphology0.60009465
94MP0001293_anophthalmia0.58268727
95MP0003656_abnormal_erythrocyte_physiolo0.58070457
96MP0009765_abnormal_xenobiotic_induced0.57967975
97MP0005636_abnormal_mineral_homeostasis0.57859151
98MP0008995_early_reproductive_senescence0.57222416
99MP0000762_abnormal_tongue_morphology0.56999508
100MP0000372_irregular_coat_pigmentation0.56782559
101MP0002102_abnormal_ear_morphology0.56743038
102MP0004019_abnormal_vitamin_homeostasis0.56412995
103MP0003942_abnormal_urinary_system0.55877416
104MP0001963_abnormal_hearing_physiology0.54669420
105MP0003806_abnormal_nucleotide_metabolis0.53882998
106MP0005164_abnormal_response_to0.53791142
107MP0003634_abnormal_glial_cell0.53440275
108MP0002876_abnormal_thyroid_physiology0.53433666
109MP0003633_abnormal_nervous_system0.53383588
110MP0003755_abnormal_palate_morphology0.53328077
111MP0002084_abnormal_developmental_patter0.53021411
112MP0003329_amyloid_beta_deposits0.52664060
113MP0002132_abnormal_respiratory_system0.51765782
114MP0003880_abnormal_central_pattern0.51060718
115MP0003453_abnormal_keratinocyte_physiol0.51045171
116MP0002557_abnormal_social/conspecific_i0.50385370
117MP0000778_abnormal_nervous_system0.50050429
118MP0002152_abnormal_brain_morphology0.49439185
119MP0002229_neurodegeneration0.47183556
120MP0005423_abnormal_somatic_nervous0.45381012
121MP0002752_abnormal_somatic_nervous0.43956943
122MP0002909_abnormal_adrenal_gland0.43759660
123MP0003279_aneurysm0.42741401
124MP0003861_abnormal_nervous_system0.42714560
125MP0001529_abnormal_vocalization0.41986498
126MP0002736_abnormal_nociception_after0.41716186
127MP0001986_abnormal_taste_sensitivity0.41564636
128MP0001486_abnormal_startle_reflex0.41470333
129MP0002089_abnormal_postnatal_growth/wei0.41361280
130MP0006054_spinal_hemorrhage0.40960453
131MP0000358_abnormal_cell_content/0.40551222
132MP0001324_abnormal_eye_pigmentation0.40288840
133MP0003699_abnormal_female_reproductive0.39378283
134MP0002092_abnormal_eye_morphology0.38632129
135MP0004811_abnormal_neuron_physiology0.38266779
136MP0006072_abnormal_retinal_apoptosis0.36745998
137MP0001764_abnormal_homeostasis0.36546513
138MP0000534_abnormal_ureter_morphology0.36451822
139MP0008569_lethality_at_weaning0.36058382
140MP0003950_abnormal_plasma_membrane0.33653135
141MP0008770_decreased_survivor_rate0.32719129
142MP0003631_nervous_system_phenotype0.32702158
143MP0002882_abnormal_neuron_morphology0.31611321
144MP0008872_abnormal_physiological_respon0.31185547
145MP0001485_abnormal_pinna_reflex0.30142216
146MP0002971_abnormal_brown_adipose0.30118973
147MP0004145_abnormal_muscle_electrophysio0.28128832
148MP0001119_abnormal_female_reproductive0.27860693
149MP0000313_abnormal_cell_death0.27579702
150MP0001502_abnormal_circadian_rhythm0.27048620
151MP0003693_abnormal_embryo_hatching0.26994924
152MP0005666_abnormal_adipose_tissue0.26817177
153MP0006036_abnormal_mitochondrial_physio0.26278362
154MP0004043_abnormal_pH_regulation0.25296518
155MP0001440_abnormal_grooming_behavior0.25108826

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.44299915
2Abnormal respiratory epithelium morphology (HP:0012253)9.44299915
3Abnormal ciliary motility (HP:0012262)8.91226520
4Rhinitis (HP:0012384)8.68800825
5Chronic bronchitis (HP:0004469)6.57224387
6Nasal polyposis (HP:0100582)6.37431660
7Infertility (HP:0000789)6.10986263
8Bronchiectasis (HP:0002110)5.18433165
9Abnormality of the nasal mucosa (HP:0000433)5.15977087
10Male infertility (HP:0003251)4.22363092
11Bronchitis (HP:0012387)4.09186955
12Nephronophthisis (HP:0000090)4.02833372
13Abnormality of the renal medulla (HP:0100957)3.27295233
14Recurrent otitis media (HP:0000403)3.21547555
15Recurrent sinusitis (HP:0011108)3.17035097
16Tubulointerstitial nephritis (HP:0001970)3.15046888
17Chronic otitis media (HP:0000389)3.13675185
18Chronic hepatic failure (HP:0100626)2.90924688
19Abnormality of midbrain morphology (HP:0002418)2.79419814
20Molar tooth sign on MRI (HP:0002419)2.79419814
21Medial flaring of the eyebrow (HP:0010747)2.75217985
22Supernumerary spleens (HP:0009799)2.66711707
23Abnormality of the lower motor neuron (HP:0002366)2.61338187
24Chronic sinusitis (HP:0011109)2.58529646
25Atelectasis (HP:0100750)2.58129602
26Abnormality of dentin (HP:0010299)2.50099819
27Tubulointerstitial abnormality (HP:0001969)2.45550583
28Tubular atrophy (HP:0000092)2.44299231
29Recurrent bronchitis (HP:0002837)2.43828667
30Hyperactive renin-angiotensin system (HP:0000841)2.38520435
31Congenital hepatic fibrosis (HP:0002612)2.32501036
32Pancreatic fibrosis (HP:0100732)2.30358812
33Abnormal spermatogenesis (HP:0008669)2.26211422
34Cystic liver disease (HP:0006706)2.22983324
35Impulsivity (HP:0100710)2.21913274
36Postaxial foot polydactyly (HP:0001830)2.20505186
37Short nail (HP:0001799)2.20393467
38Anencephaly (HP:0002323)2.19130722
39Amyotrophic lateral sclerosis (HP:0007354)2.08585122
40Male pseudohermaphroditism (HP:0000037)2.08347159
41Abnormality of permanent molar morphology (HP:0011071)2.05961857
42Abnormality of the dental root (HP:0006486)2.05961857
43Taurodontia (HP:0000679)2.05961857
44True hermaphroditism (HP:0010459)2.05835531
45Hypoplasia of the capital femoral epiphysis (HP:0003090)2.03716648
46Stage 5 chronic kidney disease (HP:0003774)2.02251703
47Gonadotropin excess (HP:0000837)2.01196573
48Abnormal drinking behavior (HP:0030082)2.01036820
49Polydipsia (HP:0001959)2.01036820
50Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.5972106
51Dynein arm defect of respiratory motile cilia (HP:0012255)11.6124645
52Absent/shortened dynein arms (HP:0200106)11.6124645
53Abnormal respiratory motile cilium physiology (HP:0012261)10.1420394
54Fibular hypoplasia (HP:0003038)1.97551838
55Median cleft lip (HP:0000161)1.95172152
56Occipital encephalocele (HP:0002085)1.93277295
57Oculomotor apraxia (HP:0000657)1.92859868
58Abnormality of molar morphology (HP:0011070)1.91462902
59Abnormality of molar (HP:0011077)1.91462902
60Congenital primary aphakia (HP:0007707)1.90424036
61Gait imbalance (HP:0002141)1.90144253
62Hemiparesis (HP:0001269)1.89165430
63Abnormal biliary tract physiology (HP:0012439)1.88634154
64Bile duct proliferation (HP:0001408)1.88634154
65Sclerocornea (HP:0000647)1.85595825
66Tubulointerstitial fibrosis (HP:0005576)1.85513498
67Aplasia/Hypoplasia of the spleen (HP:0010451)1.82653659
68Abnormality of the dental pulp (HP:0006479)1.82056917
69Asplenia (HP:0001746)1.81851109
70Abnormality of renal excretion (HP:0011036)1.80483640
71Postaxial hand polydactyly (HP:0001162)1.80103930
72Abnormal gallbladder physiology (HP:0012438)1.79916465
73Cholecystitis (HP:0001082)1.79916465
74Short ribs (HP:0000773)1.78172198
75Aplasia/Hypoplasia of the tongue (HP:0010295)1.75883693
76Genital tract atresia (HP:0001827)1.73893724
77Facial cleft (HP:0002006)1.73297692
78Renal dysplasia (HP:0000110)1.72843331
79Retinal dysplasia (HP:0007973)1.70260532
80Dyschromatopsia (HP:0007641)1.69428871
81Broad distal phalanx of finger (HP:0009836)1.69149734
82Pancreatic cysts (HP:0001737)1.69019622
83Nephrogenic diabetes insipidus (HP:0009806)1.65569554
84Abnormal urine output (HP:0012590)1.65550535
85Bony spicule pigmentary retinopathy (HP:0007737)1.65088099
86Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.63770200
87Absent epiphyses (HP:0010577)1.63770200
88Heterotopia (HP:0002282)1.61570419
89J-shaped sella turcica (HP:0002680)1.56667471
90Furrowed tongue (HP:0000221)1.56242975
91Nephropathy (HP:0000112)1.55884190
92Decreased circulating renin level (HP:0003351)1.54437203
93Impaired proprioception (HP:0010831)1.50372522
94Spastic tetraparesis (HP:0001285)1.49300702
95Renal salt wasting (HP:0000127)1.48848375
96Azoospermia (HP:0000027)1.48630319
97Abnormality of the renal cortex (HP:0011035)1.48540417
98Facial shape deformation (HP:0011334)1.47023268
99Potter facies (HP:0002009)1.47023268
100Aplasia/Hypoplasia of the sacrum (HP:0008517)1.46086103
101Aplasia/Hypoplasia of the lens (HP:0008063)1.44870667
102Bifid scrotum (HP:0000048)1.44727827
103Bell-shaped thorax (HP:0001591)1.42986278
104Decreased central vision (HP:0007663)1.42573750
105Poor coordination (HP:0002370)1.38304901
106Choroideremia (HP:0001139)1.33978124
107Cone-rod dystrophy (HP:0000548)1.31457636
108Attenuation of retinal blood vessels (HP:0007843)1.30033127
109Degeneration of anterior horn cells (HP:0002398)1.29593591
110Abnormality of the anterior horn cell (HP:0006802)1.29593591
111Vaginal atresia (HP:0000148)1.27018038
112Popliteal pterygium (HP:0009756)1.26967224
113Short femoral neck (HP:0100864)1.26605133
114Deformed sella turcica (HP:0002681)1.26572892
115Abnormality of abdominal situs (HP:0011620)1.26411299
116Abdominal situs inversus (HP:0003363)1.26411299
117Short thorax (HP:0010306)1.26398359
118Preaxial hand polydactyly (HP:0001177)1.25935037
119Absent frontal sinuses (HP:0002688)1.24675669
120Polyuria (HP:0000103)1.24323698
121Aplasia of the musculature (HP:0100854)1.24129706
122Absent rod-and cone-mediated responses on ERG (HP:0007688)1.19981148
123Retinitis pigmentosa (HP:0000510)1.18418149
124Aganglionic megacolon (HP:0002251)1.15969433
125Narrow forehead (HP:0000341)1.15343735
126Hyperkalemia (HP:0002153)1.13757991
127Hyperaldosteronism (HP:0000859)1.12907672
128Multicystic kidney dysplasia (HP:0000003)1.11464874
129Vascular calcification (HP:0004934)1.11198852
130Abnormality of renin-angiotensin system (HP:0000847)1.09029764

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.87561181
2PDK47.87561181
3TESK15.17981652
4PDK24.95666273
5MST44.72411360
6EPHA24.50991280
7PRKD34.06505295
8ICK4.02245797
9PNCK2.95028068
10TLK12.94451942
11MAPK152.25334025
12PTK2B2.23856285
13NME12.20851429
14MST1R1.99921580
15NEK21.99669668
16WNK41.99174352
17EEF2K1.97051647
18STK241.83926913
19STK391.74576164
20NEK61.67564775
21STK381.61066069
22DYRK1B1.50304537
23MAP3K21.46872558
24EPHA31.42799514
25MUSK1.41619331
26BCR1.40162564
27PRKCI1.35637667
28LRRK21.34648579
29CDC71.20348198
30MAP3K101.14774718
31MAP3K121.14491393
32SMG11.11896331
33STK161.08709758
34MAP3K41.05034780
35MET1.03867025
36DYRK31.03123374
37MAP3K30.98868664
38CAMK1G0.98363258
39FGFR20.98068344
40WNK10.95099880
41PBK0.92743067
42TRIB30.91721534
43TTK0.90732878
44VRK10.86974179
45PDK10.86714749
46CDK80.86052832
47WEE10.85715053
48TYRO30.84741938
49INSRR0.82245741
50ERBB30.78041801
51MAP2K40.77413729
52TESK20.74672099
53PRKCG0.70910942
54CDK30.68474670
55ABL20.64807866
56NTRK20.64675657
57EPHB20.64246157
58PASK0.64094384
59BRD40.60609477
60LMTK20.60597716
61IRAK10.59731474
62PIM20.59327966
63CHEK20.58034018
64ARAF0.56169332
65LIMK10.55265858
66CHEK10.54839377
67PINK10.54375698
68TAOK10.54088999
69MAP3K70.52270052
70TSSK60.51903319
71CDK120.51893918
72CAMKK10.51598313
73STK30.51418574
74AURKB0.49307104
75CHUK0.49093889
76ERBB20.48931539
77PLK40.48772399
78STK100.43749186
79AKT20.43710111
80PDPK10.42990807
81GRK60.42913449
82AURKA0.42248921
83GRK10.42126406
84ZAK0.41848819
85TRIM280.41530958
86CCNB10.41140165
87MAPKAPK50.38248194
88VRK20.38046658
89BMPR1B0.37555283
90MAP2K70.37539346
91ATR0.37363618
92PLK10.37096689
93MAPK120.36867348
94ATM0.36504018
95CAMK2G0.36467196
96ADRBK10.36237275
97PRKCQ0.35493359
98CDK90.35472748
99MTOR0.34256965
100TRPM70.34077367
101TGFBR10.33215282
102MARK20.33095973
103PAK40.32241245
104MAPKAPK30.31925858
105TBK10.31203615
106WNK30.31181376
107PRKCD0.30540030
108PAK10.28541433
109PRKAA10.27856590
110MAPK110.26955382
111EIF2AK30.25606510
112PRKACA0.25523330
113PTK60.25353088
114MAP4K20.25124454
115CDK70.23644380
116RIPK40.23624519
117MINK10.23488309
118PKN10.21721327
119RPS6KB10.20223806
120PAK20.19390880
121NEK90.19321264
122MAP3K60.18015783
123CSNK1G20.17939518
124MAP3K50.17844610
125BRSK20.17517305
126RPS6KA50.17308527
127STK40.16766771
128PRKCZ0.16668249
129MAPK70.15734052
130CSNK1D0.15310259
131PRKCA0.14884807
132ERBB40.14228158
133BUB10.13365262
134CAMK1D0.13028947
135GSK3B0.11972351
136CDK150.11774449
137CDK10.11557280
138CAMKK20.11424300
139PRKCB0.11136345
140PRKACG0.10679045
141MAPK80.10526867
142MAP4K10.10264593
143CDK11A0.09518723
144BRSK10.09395810
145CDK20.09349510
146CDK180.09271044
147STK110.08420359
148MAPK100.08417425
149MAP3K110.08296965
150CSK0.08066205
151CSNK2A10.07578620
152RPS6KA10.06673814
153IRAK20.06588351
154DAPK20.06381536
155MAP2K60.05842367
156PRKDC0.05612435
157RPS6KB20.03051490
158MAPK40.02957840
159CSNK1E0.02574815
160FRK0.02540075
161STK38L0.02440022
162CDK140.02426171
163SRC0.02117189
164RPS6KA30.02071525
165CSNK2A20.02018966

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.07755646
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.95348410
3Vitamin B6 metabolism_Homo sapiens_hsa007503.94182594
4Phenylalanine metabolism_Homo sapiens_hsa003603.64099893
5Pyruvate metabolism_Homo sapiens_hsa006203.45935054
6Histidine metabolism_Homo sapiens_hsa003403.44992834
7Tyrosine metabolism_Homo sapiens_hsa003502.85488548
8alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.79030191
9Oxidative phosphorylation_Homo sapiens_hsa001902.78011808
10Propanoate metabolism_Homo sapiens_hsa006402.74314181
11Olfactory transduction_Homo sapiens_hsa047402.72641556
12Linoleic acid metabolism_Homo sapiens_hsa005912.66266109
13beta-Alanine metabolism_Homo sapiens_hsa004102.48781058
14Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.48597746
15Caffeine metabolism_Homo sapiens_hsa002322.24729610
16Glucagon signaling pathway_Homo sapiens_hsa049222.21678184
17Basal transcription factors_Homo sapiens_hsa030222.18127380
18Phototransduction_Homo sapiens_hsa047442.13286615
19Ribosome_Homo sapiens_hsa030101.97547795
20Parkinsons disease_Homo sapiens_hsa050121.96404972
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.94154903
22Huntingtons disease_Homo sapiens_hsa050161.91385542
23Dorso-ventral axis formation_Homo sapiens_hsa043201.91098228
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.87394057
25Oocyte meiosis_Homo sapiens_hsa041141.82136284
26Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.82085239
27Selenocompound metabolism_Homo sapiens_hsa004501.81297051
28Glycerophospholipid metabolism_Homo sapiens_hsa005641.80778183
29Ether lipid metabolism_Homo sapiens_hsa005651.76861712
30Retinol metabolism_Homo sapiens_hsa008301.76829338
31Carbohydrate digestion and absorption_Homo sapiens_hsa049731.76474233
32Sphingolipid metabolism_Homo sapiens_hsa006001.67076955
33Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.61758825
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.61679533
35Glycerolipid metabolism_Homo sapiens_hsa005611.60184101
36Pentose phosphate pathway_Homo sapiens_hsa000301.58751834
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.50463365
38Alzheimers disease_Homo sapiens_hsa050101.47959009
39Fanconi anemia pathway_Homo sapiens_hsa034601.47606892
40PPAR signaling pathway_Homo sapiens_hsa033201.46511313
41Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.46360981
42Fructose and mannose metabolism_Homo sapiens_hsa000511.45314714
43Carbon metabolism_Homo sapiens_hsa012001.42658558
44Cysteine and methionine metabolism_Homo sapiens_hsa002701.41990733
45Purine metabolism_Homo sapiens_hsa002301.40985958
46Peroxisome_Homo sapiens_hsa041461.35678332
47Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.35234294
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.32788550
49mRNA surveillance pathway_Homo sapiens_hsa030151.32468004
50Tight junction_Homo sapiens_hsa045301.30452315
51Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.27155273
52Antigen processing and presentation_Homo sapiens_hsa046121.26818768
53Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.22650609
54Cardiac muscle contraction_Homo sapiens_hsa042601.21825045
55RNA transport_Homo sapiens_hsa030131.15931773
56Fat digestion and absorption_Homo sapiens_hsa049751.12642507
57Renin secretion_Homo sapiens_hsa049241.12133109
58Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.11891711
59Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.11045405
60Steroid hormone biosynthesis_Homo sapiens_hsa001401.09922697
61Amphetamine addiction_Homo sapiens_hsa050311.06949126
62Arachidonic acid metabolism_Homo sapiens_hsa005901.04108477
63Mineral absorption_Homo sapiens_hsa049781.03468899
64Fatty acid metabolism_Homo sapiens_hsa012121.00313881
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.96553591
66Fatty acid degradation_Homo sapiens_hsa000710.95967574
67Systemic lupus erythematosus_Homo sapiens_hsa053220.94289502
68Biosynthesis of amino acids_Homo sapiens_hsa012300.93854855
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.91912177
70Homologous recombination_Homo sapiens_hsa034400.91317316
71Synaptic vesicle cycle_Homo sapiens_hsa047210.89392345
72Bile secretion_Homo sapiens_hsa049760.89095918
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88547568
74Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.88365062
75Pyrimidine metabolism_Homo sapiens_hsa002400.88175638
76Circadian rhythm_Homo sapiens_hsa047100.86034312
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82860447
78RNA polymerase_Homo sapiens_hsa030200.82323538
79Glutathione metabolism_Homo sapiens_hsa004800.81272748
80Base excision repair_Homo sapiens_hsa034100.81101157
81Proteasome_Homo sapiens_hsa030500.79524233
82Renin-angiotensin system_Homo sapiens_hsa046140.79384767
83Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77903759
84Insulin secretion_Homo sapiens_hsa049110.76847820
85Calcium signaling pathway_Homo sapiens_hsa040200.75682423
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75268359
87Sulfur relay system_Homo sapiens_hsa041220.74690843
88Mismatch repair_Homo sapiens_hsa034300.73083831
89Protein export_Homo sapiens_hsa030600.72966268
90Hedgehog signaling pathway_Homo sapiens_hsa043400.72719691
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.70480170
92Estrogen signaling pathway_Homo sapiens_hsa049150.67517901
93Inositol phosphate metabolism_Homo sapiens_hsa005620.66031407
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65927295
95Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64862588
96Long-term potentiation_Homo sapiens_hsa047200.64361899
97Adipocytokine signaling pathway_Homo sapiens_hsa049200.63617823
98ABC transporters_Homo sapiens_hsa020100.62921968
99Collecting duct acid secretion_Homo sapiens_hsa049660.62877956
100Hippo signaling pathway_Homo sapiens_hsa043900.59748907
101Chemical carcinogenesis_Homo sapiens_hsa052040.58978318
102Butanoate metabolism_Homo sapiens_hsa006500.58231282
103Pancreatic secretion_Homo sapiens_hsa049720.57824512
104Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57201734
105Drug metabolism - other enzymes_Homo sapiens_hsa009830.56173651
106Thyroid hormone synthesis_Homo sapiens_hsa049180.55800036
107Alcoholism_Homo sapiens_hsa050340.55426053
108Glycosaminoglycan degradation_Homo sapiens_hsa005310.55164003
109Notch signaling pathway_Homo sapiens_hsa043300.52864806
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52146848
111Nitrogen metabolism_Homo sapiens_hsa009100.51382446
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51289960
113Folate biosynthesis_Homo sapiens_hsa007900.51191085
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50865488
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50470561
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50317608
117Other glycan degradation_Homo sapiens_hsa005110.49102311
118Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.46480020
119cAMP signaling pathway_Homo sapiens_hsa040240.45354549
120Arginine and proline metabolism_Homo sapiens_hsa003300.45272606
121cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44790297
122Gastric acid secretion_Homo sapiens_hsa049710.43778655
123Basal cell carcinoma_Homo sapiens_hsa052170.43037725
124Metabolic pathways_Homo sapiens_hsa011000.42720186
125Spliceosome_Homo sapiens_hsa030400.42069896
126p53 signaling pathway_Homo sapiens_hsa041150.40829449
127Hepatitis C_Homo sapiens_hsa051600.40416274
128Lysosome_Homo sapiens_hsa041420.39947248
129Salivary secretion_Homo sapiens_hsa049700.39284956
130Glutamatergic synapse_Homo sapiens_hsa047240.38552410
131Viral carcinogenesis_Homo sapiens_hsa052030.38268049
132DNA replication_Homo sapiens_hsa030300.37461696
133Cell cycle_Homo sapiens_hsa041100.37153989
134Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.36870418
135Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.35902975
136Maturity onset diabetes of the young_Homo sapiens_hsa049500.34927821
137Legionellosis_Homo sapiens_hsa051340.34686097
138Nucleotide excision repair_Homo sapiens_hsa034200.34149124
139Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.33294639
140Cocaine addiction_Homo sapiens_hsa050300.32862495
141AMPK signaling pathway_Homo sapiens_hsa041520.31583584
142RNA degradation_Homo sapiens_hsa030180.31037913
143Wnt signaling pathway_Homo sapiens_hsa043100.29002698
144N-Glycan biosynthesis_Homo sapiens_hsa005100.28847139
145Circadian entrainment_Homo sapiens_hsa047130.28826155
146Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28056042
147Taste transduction_Homo sapiens_hsa047420.26237683
148Starch and sucrose metabolism_Homo sapiens_hsa005000.26167922
149VEGF signaling pathway_Homo sapiens_hsa043700.25500500
150Nicotine addiction_Homo sapiens_hsa050330.25146052
151Steroid biosynthesis_Homo sapiens_hsa001000.24938449
152Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23814240
153Axon guidance_Homo sapiens_hsa043600.22869908
154Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.22188513
155Vascular smooth muscle contraction_Homo sapiens_hsa042700.20898222
156Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.20855180
157Vibrio cholerae infection_Homo sapiens_hsa051100.19728106
158Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.19047384
159Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.18669993
160Prostate cancer_Homo sapiens_hsa052150.17486762
161Transcriptional misregulation in cancer_Homo sapiens_hsa052020.16827907

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