IQCC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1doxorubicin metabolic process (GO:0044598)5.59690371
2daunorubicin metabolic process (GO:0044597)5.59690371
3polyketide metabolic process (GO:0030638)5.59690371
4behavioral response to nicotine (GO:0035095)4.84350855
5axon ensheathment in central nervous system (GO:0032291)4.47766737
6central nervous system myelination (GO:0022010)4.47766737
7mannosylation (GO:0097502)4.43152433
8mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.30569119
9mitochondrial respiratory chain complex I assembly (GO:0032981)4.30569119
10NADH dehydrogenase complex assembly (GO:0010257)4.30569119
11L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.14945852
12GPI anchor biosynthetic process (GO:0006506)4.08775868
13N-acetylneuraminate metabolic process (GO:0006054)3.99830240
14energy coupled proton transport, down electrochemical gradient (GO:0015985)3.86565068
15ATP synthesis coupled proton transport (GO:0015986)3.86565068
16protein complex biogenesis (GO:0070271)3.77056463
17chaperone-mediated protein transport (GO:0072321)3.73330130
18mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.71815862
19preassembly of GPI anchor in ER membrane (GO:0016254)3.70386857
20aminoglycoside antibiotic metabolic process (GO:0030647)3.68064156
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.67579553
22fatty acid elongation (GO:0030497)3.65843652
23cullin deneddylation (GO:0010388)3.61721357
24presynaptic membrane assembly (GO:0097105)3.55741242
25somatic hypermutation of immunoglobulin genes (GO:0016446)3.51692067
26somatic diversification of immune receptors via somatic mutation (GO:0002566)3.51692067
27GPI anchor metabolic process (GO:0006505)3.50887345
28response to pheromone (GO:0019236)3.50454128
29DNA deamination (GO:0045006)3.48696947
30quinone biosynthetic process (GO:1901663)3.48309609
31ubiquinone biosynthetic process (GO:0006744)3.48309609
32tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.46059335
33RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.46059335
34centriole assembly (GO:0098534)3.45675345
35regulation of RIG-I signaling pathway (GO:0039535)3.44775095
36replication fork processing (GO:0031297)3.44215020
37detection of light stimulus involved in visual perception (GO:0050908)3.43074677
38detection of light stimulus involved in sensory perception (GO:0050962)3.43074677
39presynaptic membrane organization (GO:0097090)3.39708193
40regulation of cilium movement (GO:0003352)3.38312094
41ubiquinone metabolic process (GO:0006743)3.38108627
42protein deneddylation (GO:0000338)3.37242780
43epithelial cilium movement (GO:0003351)3.36608544
44C-terminal protein lipidation (GO:0006501)3.35374590
45piRNA metabolic process (GO:0034587)3.33559171
46DNA double-strand break processing (GO:0000729)3.30143897
47GDP-mannose metabolic process (GO:0019673)3.29181850
48DNA replication checkpoint (GO:0000076)3.24748803
49base-excision repair, AP site formation (GO:0006285)3.22574174
50meiotic chromosome segregation (GO:0045132)3.20322014
51pseudouridine synthesis (GO:0001522)3.19275993
52GTP biosynthetic process (GO:0006183)3.19171677
53mitochondrial respiratory chain complex assembly (GO:0033108)3.18203162
54DNA strand renaturation (GO:0000733)3.17723512
55signal peptide processing (GO:0006465)3.17646933
56reciprocal meiotic recombination (GO:0007131)3.16678363
57reciprocal DNA recombination (GO:0035825)3.16678363
58rRNA modification (GO:0000154)3.14717527
59amino acid salvage (GO:0043102)3.14291400
60L-methionine salvage (GO:0071267)3.14291400
61L-methionine biosynthetic process (GO:0071265)3.14291400
62epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.12729321
63respiratory electron transport chain (GO:0022904)3.12579358
64respiratory chain complex IV assembly (GO:0008535)3.12313071
65long-chain fatty acid biosynthetic process (GO:0042759)3.09169757
66negative regulation of telomere maintenance (GO:0032205)3.08430121
67regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.07903096
68DNA methylation involved in gamete generation (GO:0043046)3.07150489
69electron transport chain (GO:0022900)3.05027133
70mast cell activation (GO:0045576)3.05011801
71rRNA methylation (GO:0031167)3.04884188
72cytochrome complex assembly (GO:0017004)3.03721788
73nonmotile primary cilium assembly (GO:0035058)3.03572075
74protein neddylation (GO:0045116)3.02845072
75quinone metabolic process (GO:1901661)3.01581095
76positive regulation of mitochondrial fission (GO:0090141)3.01507864
77C-terminal protein amino acid modification (GO:0018410)3.01191713
78synapsis (GO:0007129)2.99233449
79ribosomal small subunit assembly (GO:0000028)2.97821634
80mast cell activation involved in immune response (GO:0002279)2.95768271
81mast cell degranulation (GO:0043303)2.95768271
82microtubule depolymerization (GO:0007019)2.95168332
83male meiosis (GO:0007140)2.94923177
84intraciliary transport (GO:0042073)2.93981110
85guanosine-containing compound biosynthetic process (GO:1901070)2.93800211
86transcription elongation from RNA polymerase III promoter (GO:0006385)2.93606668
87termination of RNA polymerase III transcription (GO:0006386)2.93606668
88proteasome assembly (GO:0043248)2.93421101
89male meiosis I (GO:0007141)2.90675682
90regulation of nuclear cell cycle DNA replication (GO:0033262)2.89794004
91sperm motility (GO:0030317)2.87513993
92L-fucose catabolic process (GO:0042355)2.86510705
93fucose catabolic process (GO:0019317)2.86510705
94L-fucose metabolic process (GO:0042354)2.86510705
95mitochondrial RNA metabolic process (GO:0000959)2.83649221
96platelet dense granule organization (GO:0060155)2.80769411
97cilium or flagellum-dependent cell motility (GO:0001539)2.80763690
98negative regulation of osteoblast proliferation (GO:0033689)2.80720428
99S-adenosylmethionine metabolic process (GO:0046500)2.80597085
100cilium movement (GO:0003341)2.80412596
101protein K6-linked ubiquitination (GO:0085020)2.79940265
102axonemal dynein complex assembly (GO:0070286)2.79862786
103cellular ketone body metabolic process (GO:0046950)2.77680787
104water-soluble vitamin biosynthetic process (GO:0042364)2.76751627
105RNA capping (GO:0036260)2.76225144
1067-methylguanosine RNA capping (GO:0009452)2.76225144
107antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.75939024
108pyrimidine dimer repair (GO:0006290)2.73957851
109glycolipid biosynthetic process (GO:0009247)2.73305975
110peptidyl-histidine modification (GO:0018202)2.72915920
1117-methylguanosine mRNA capping (GO:0006370)2.72870499
112tRNA modification (GO:0006400)2.71866828
113cilium morphogenesis (GO:0060271)2.70790731
114dopamine transport (GO:0015872)2.70255741
115deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.69738677
116eye photoreceptor cell differentiation (GO:0001754)2.68657229
117photoreceptor cell differentiation (GO:0046530)2.68657229
118axoneme assembly (GO:0035082)2.68037675
119regulation of mitochondrial translation (GO:0070129)2.67728557
120regulation of metalloenzyme activity (GO:0048552)2.67400225
121recombinational repair (GO:0000725)2.67305087
122cyclooxygenase pathway (GO:0019371)2.66955761
123DNA ligation (GO:0006266)2.66866246
124regulation of pigment cell differentiation (GO:0050932)2.66364121
125cilium organization (GO:0044782)2.65749771
126protein-cofactor linkage (GO:0018065)2.64990593
127multicellular organism reproduction (GO:0032504)2.64332917
128double-strand break repair via homologous recombination (GO:0000724)2.63368198
129maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.63256299
130dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.62761969
131response to redox state (GO:0051775)2.61920660
132tRNA metabolic process (GO:0006399)2.61407012
133isoprenoid biosynthetic process (GO:0008299)2.61034938
134CTP metabolic process (GO:0046036)2.60485184
135CTP biosynthetic process (GO:0006241)2.60485184
136cilium assembly (GO:0042384)2.60198042
137aerobic respiration (GO:0009060)2.59702288
138positive regulation of granulocyte differentiation (GO:0030854)2.57990784
139ketone body metabolic process (GO:1902224)2.57710516
140tRNA methylation (GO:0030488)2.55547049
141regulation of microtubule-based movement (GO:0060632)2.55523319
142heart process (GO:0003015)2.55197684
143heart contraction (GO:0060047)2.55197684
144deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.54734044
145histamine secretion (GO:0001821)2.54414382
146histone H2A acetylation (GO:0043968)2.53547243
147nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.52120519
148positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.52078704
149resolution of meiotic recombination intermediates (GO:0000712)2.51579748
150substantia nigra development (GO:0021762)2.50709284
151estrogen biosynthetic process (GO:0006703)2.50459425
152purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.50417067
153protein import into peroxisome matrix (GO:0016558)2.49273974
154iron-sulfur cluster assembly (GO:0016226)2.49265502
155metallo-sulfur cluster assembly (GO:0031163)2.49265502
156neurotransmitter uptake (GO:0001504)2.48926952
157UTP biosynthetic process (GO:0006228)2.47962168
158GMP metabolic process (GO:0046037)2.47745130
159protein localization to cilium (GO:0061512)2.47588754
160DNA replication-dependent nucleosome organization (GO:0034723)2.46875506
161DNA replication-dependent nucleosome assembly (GO:0006335)2.46875506
162spinal cord motor neuron differentiation (GO:0021522)2.45941267
163negative regulation of cell aging (GO:0090344)2.44560027
164spermatid development (GO:0007286)2.44368569
165methionine biosynthetic process (GO:0009086)2.44202033
166lymphoid progenitor cell differentiation (GO:0002320)2.44005387
167exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.43904880
168positive regulation of cellular amine metabolic process (GO:0033240)2.42180131
169histamine transport (GO:0051608)2.41661278
170regulation of oxidative phosphorylation (GO:0002082)2.41392690
171centriole replication (GO:0007099)2.41298756
172tRNA processing (GO:0008033)2.38497953

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.68352507
2GBX2_23144817_ChIP-Seq_PC3_Human3.60092012
3EZH2_22144423_ChIP-Seq_EOC_Human3.52787538
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.35848179
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.35036018
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.02436155
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.91711576
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.88130299
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.83550349
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.82631967
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.78275839
12SRF_21415370_ChIP-Seq_HL-1_Mouse2.65815163
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.64024753
14* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.49447710
15PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.41395562
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.31145554
17VDR_22108803_ChIP-Seq_LS180_Human2.25891450
18TAF15_26573619_Chip-Seq_HEK293_Human2.17452621
19IRF8_22096565_ChIP-ChIP_GC-B_Human2.05015850
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04926156
21SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.04275408
22IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.02211009
23SALL1_21062744_ChIP-ChIP_HESCs_Human2.00234509
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.95423099
25FUS_26573619_Chip-Seq_HEK293_Human1.93697427
26GABP_19822575_ChIP-Seq_HepG2_Human1.92065523
27TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.91056266
28ERG_20887958_ChIP-Seq_HPC-7_Mouse1.89751553
29POU3F2_20337985_ChIP-ChIP_501MEL_Human1.88839609
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.86816125
31EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.86672417
32LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.86200107
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.86112465
34SCL_19346495_ChIP-Seq_HPC-7_Human1.84264946
35* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.83424126
36* XRN2_22483619_ChIP-Seq_HELA_Human1.80867375
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.76613414
38CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.76079460
39IGF1R_20145208_ChIP-Seq_DFB_Human1.71387327
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.70260482
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.69197453
42BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.68181950
43KDM5A_27292631_Chip-Seq_BREAST_Human1.61639660
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.60823815
45IRF1_19129219_ChIP-ChIP_H3396_Human1.60361106
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.60206374
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58232138
48TP63_19390658_ChIP-ChIP_HaCaT_Human1.56268176
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.55087701
50TP53_22573176_ChIP-Seq_HFKS_Human1.54490976
51CIITA_25753668_ChIP-Seq_RAJI_Human1.52025999
52FOXP3_21729870_ChIP-Seq_TREG_Human1.52014267
53TTF2_22483619_ChIP-Seq_HELA_Human1.50872135
54E2F7_22180533_ChIP-Seq_HELA_Human1.48336770
55FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.48082708
56VDR_23849224_ChIP-Seq_CD4+_Human1.46296983
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44734307
58ELK1_19687146_ChIP-ChIP_HELA_Human1.43190996
59ERA_21632823_ChIP-Seq_H3396_Human1.42048931
60* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41945838
61CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39196509
62THAP11_20581084_ChIP-Seq_MESCs_Mouse1.33264148
63CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33178919
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.32563511
65P300_19829295_ChIP-Seq_ESCs_Human1.31537056
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.30834965
67* NANOG_20526341_ChIP-Seq_ESCs_Human1.29820863
68ER_23166858_ChIP-Seq_MCF-7_Human1.29293223
69MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.29240630
70IRF8_21731497_ChIP-ChIP_J774_Mouse1.29230139
71CREB1_15753290_ChIP-ChIP_HEK293T_Human1.26264436
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24887878
73TAL1_26923725_Chip-Seq_HPCs_Mouse1.23932047
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.23759767
75EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.23055673
76NCOR_22424771_ChIP-Seq_293T_Human1.22253270
77PADI4_21655091_ChIP-ChIP_MCF-7_Human1.20848576
78* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20638653
79MYC_18555785_ChIP-Seq_MESCs_Mouse1.15949944
80HTT_18923047_ChIP-ChIP_STHdh_Human1.15221923
81RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.14775358
82NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.14607175
83MYC_19829295_ChIP-Seq_ESCs_Human1.14174201
84HOXB7_26014856_ChIP-Seq_BT474_Human1.13893685
85FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.13340871
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13327237
87GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.11864486
88* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.11672385
89TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10692594
90RAC3_21632823_ChIP-Seq_H3396_Human1.10375326
91EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.09962338
92E2F1_20622854_ChIP-Seq_HELA_Human1.09774060
93EWS_26573619_Chip-Seq_HEK293_Human1.08915137
94SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08472533
95* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.08173788
96GATA3_21878914_ChIP-Seq_MCF-7_Human1.07516783
97OCT4_20526341_ChIP-Seq_ESCs_Human1.07331850
98FOXP1_21924763_ChIP-Seq_HESCs_Human1.06368635
99RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06135438
100NOTCH1_21737748_ChIP-Seq_TLL_Human1.06083036
101STAT3_18555785_Chip-Seq_ESCs_Mouse1.06075350
102SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05549895
103OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05442494
104SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05409681
105FOXA1_25329375_ChIP-Seq_VCAP_Human1.05097810
106FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05097810
107P53_21459846_ChIP-Seq_SAOS-2_Human1.04946659
108CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.04843993
109SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.04542335
110LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04331592
111BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03470829
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03037482
113MYC_19030024_ChIP-ChIP_MESCs_Mouse1.02040986
114YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.00511694
115TAF2_19829295_ChIP-Seq_ESCs_Human1.00313490
116NFE2_27457419_Chip-Seq_LIVER_Mouse1.00266592
117EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00046375
118ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99714782
119CBX2_27304074_Chip-Seq_ESCs_Mouse0.98197694
120SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97799814
121P53_22387025_ChIP-Seq_ESCs_Mouse0.97146778
122PHF8_20622854_ChIP-Seq_HELA_Human0.96859285
123CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96703291
124ERG_20517297_ChIP-Seq_VCAP_Human0.96459313
125AR_20517297_ChIP-Seq_VCAP_Human0.95956746
126CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95046207
127CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94462955
128ETV2_25802403_ChIP-Seq_MESCs_Mouse0.94201144
129* MYC_18358816_ChIP-ChIP_MESCs_Mouse0.94067892
130GATA1_22025678_ChIP-Seq_K562_Human0.93642857
131RUNX1_27457419_Chip-Seq_LIVER_Mouse0.93319845
132MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92566532
133STAT4_19710469_ChIP-ChIP_TH1__Mouse0.92493964
134EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.92478280
135LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.92349399
136SPI1_23547873_ChIP-Seq_NB4_Human0.91489924
137E2F1_17053090_ChIP-ChIP_MCF-7_Human0.91469287
138NANOG_18555785_Chip-Seq_ESCs_Mouse0.91073124
139BP1_19119308_ChIP-ChIP_Hs578T_Human0.91041795
140EZH2_27294783_Chip-Seq_NPCs_Mouse0.90951853
141SALL4_22934838_ChIP-ChIP_CD34+_Human0.90724760
142SOX2_19829295_ChIP-Seq_ESCs_Human0.90683384
143NANOG_19829295_ChIP-Seq_ESCs_Human0.90683384
144* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.90552978
145E2F1_21310950_ChIP-Seq_MCF-7_Human0.89817776
146GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89453006
147UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88866169
148KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88666649
149RNF2_27304074_Chip-Seq_NSC_Mouse0.88372936
150PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.88185717
151RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87989390
152MYC_18940864_ChIP-ChIP_HL60_Human0.87824459
153P300_18555785_Chip-Seq_ESCs_Mouse0.83202076
154OCT4_18555785_Chip-Seq_ESCs_Mouse0.82345023
155DCP1A_22483619_ChIP-Seq_HELA_Human0.82049250

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001986_abnormal_taste_sensitivity5.15938075
2MP0004147_increased_porphyrin_level2.99445464
3MP0004142_abnormal_muscle_tone2.81566254
4MP0001188_hyperpigmentation2.76282817
5MP0009379_abnormal_foot_pigmentation2.70461518
6MP0005409_darkened_coat_color2.64127699
7MP0003880_abnormal_central_pattern2.62659334
8MP0000372_irregular_coat_pigmentation2.46968399
9MP0010094_abnormal_chromosome_stability2.32054772
10MP0005083_abnormal_biliary_tract2.31104217
11MP0001529_abnormal_vocalization2.20365110
12MP0000015_abnormal_ear_pigmentation2.18002339
13MP0002160_abnormal_reproductive_system2.13627614
14MP0000920_abnormal_myelination2.13222052
15MP0002638_abnormal_pupillary_reflex2.11915972
16MP0002148_abnormal_hypersensitivity_rea2.11616516
17MP0003693_abnormal_embryo_hatching2.07854615
18MP0008004_abnormal_stomach_pH2.07672154
19MP0008875_abnormal_xenobiotic_pharmacok2.00856773
20MP0001905_abnormal_dopamine_level1.95310787
21MP0006072_abnormal_retinal_apoptosis1.94456429
22MP0002736_abnormal_nociception_after1.91827146
23MP0003786_premature_aging1.91246561
24MP0005253_abnormal_eye_physiology1.88783473
25MP0009697_abnormal_copulation1.85891104
26MP0008995_early_reproductive_senescence1.81371013
27MP0005075_abnormal_melanosome_morpholog1.79998758
28MP0002272_abnormal_nervous_system1.78984532
29MP0005410_abnormal_fertilization1.75954968
30MP0008789_abnormal_olfactory_epithelium1.73672157
31MP0003806_abnormal_nucleotide_metabolis1.64996363
32MP0003718_maternal_effect1.64772183
33MP0005171_absent_coat_pigmentation1.62273034
34MP0002653_abnormal_ependyma_morphology1.60337795
35MP0001929_abnormal_gametogenesis1.58873983
36MP0001968_abnormal_touch/_nociception1.58118275
37MP0005646_abnormal_pituitary_gland1.57698250
38MP0003950_abnormal_plasma_membrane1.57539847
39MP0005671_abnormal_response_to1.54010911
40MP0003698_abnormal_male_reproductive1.53756882
41MP0001485_abnormal_pinna_reflex1.46738638
42MP0004270_analgesia1.46685993
43MP0003195_calcinosis1.46616773
44MP0006292_abnormal_olfactory_placode1.45752085
45MP0002876_abnormal_thyroid_physiology1.45723636
46MP0005389_reproductive_system_phenotype1.45017432
47MP0002210_abnormal_sex_determination1.44030552
48MP0008260_abnormal_autophagy1.42335705
49MP0004133_heterotaxia1.41268914
50MP0009745_abnormal_behavioral_response1.40338045
51MP0005379_endocrine/exocrine_gland_phen1.39601925
52MP0003111_abnormal_nucleus_morphology1.39592905
53MP0005499_abnormal_olfactory_system1.38693867
54MP0005394_taste/olfaction_phenotype1.38693867
55MP0006035_abnormal_mitochondrial_morpho1.37969156
56MP0009046_muscle_twitch1.37801278
57MP0004043_abnormal_pH_regulation1.37248883
58MP0005174_abnormal_tail_pigmentation1.32912036
59MP0001919_abnormal_reproductive_system1.32543346
60MP0005423_abnormal_somatic_nervous1.31446174
61MP0005645_abnormal_hypothalamus_physiol1.29821281
62MP0009785_altered_susceptibility_to1.27694466
63MP0002064_seizures1.27270564
64MP0008877_abnormal_DNA_methylation1.26348458
65MP0001486_abnormal_startle_reflex1.26297762
66MP0002095_abnormal_skin_pigmentation1.25724532
67MP0003763_abnormal_thymus_physiology1.23536812
68MP0001145_abnormal_male_reproductive1.21619215
69MP0001984_abnormal_olfaction1.20715579
70MP0004742_abnormal_vestibular_system1.19089065
71MP0003724_increased_susceptibility_to1.18603988
72MP0000653_abnormal_sex_gland1.18003702
73MP0003077_abnormal_cell_cycle1.16117417
74MP0002067_abnormal_sensory_capabilities1.14279882
75MP0005377_hearing/vestibular/ear_phenot1.14206678
76MP0003878_abnormal_ear_physiology1.14206678
77MP0002229_neurodegeneration1.13918658
78MP0002572_abnormal_emotion/affect_behav1.13029560
79MP0008057_abnormal_DNA_replication1.12941736
80MP0002396_abnormal_hematopoietic_system1.12062729
81MP0002933_joint_inflammation1.10836928
82MP0001348_abnormal_lacrimal_gland1.09256813
83MP0008872_abnormal_physiological_respon1.08367781
84MP0002102_abnormal_ear_morphology1.06985727
85MP0006036_abnormal_mitochondrial_physio1.06317738
86MP0002735_abnormal_chemical_nociception1.06249162
87MP0000427_abnormal_hair_cycle1.06239125
88MP0003186_abnormal_redox_activity1.05787176
89MP0001963_abnormal_hearing_physiology1.04244106
90MP0005551_abnormal_eye_electrophysiolog1.03405730
91MP0002909_abnormal_adrenal_gland1.03402460
92MP0002163_abnormal_gland_morphology1.02920435
93MP0002557_abnormal_social/conspecific_i1.02140418
94MP0005391_vision/eye_phenotype1.01861716
95MP0003011_delayed_dark_adaptation1.01627835
96MP0004145_abnormal_muscle_electrophysio1.01502022
97MP0003646_muscle_fatigue1.01376854
98MP0008007_abnormal_cellular_replicative1.01096484
99MP0000490_abnormal_crypts_of1.00920835
100MP0002837_dystrophic_cardiac_calcinosis1.00702077
101MP0004885_abnormal_endolymph0.99115431
102MP0005195_abnormal_posterior_eye0.98265914
103MP0002132_abnormal_respiratory_system0.97427323
104MP0003635_abnormal_synaptic_transmissio0.97283390
105MP0004924_abnormal_behavior0.96920469
106MP0005386_behavior/neurological_phenoty0.96920469
107MP0000685_abnormal_immune_system0.96813664
108MP0003879_abnormal_hair_cell0.96509000
109MP0001790_abnormal_immune_system0.96506979
110MP0005387_immune_system_phenotype0.96506979
111MP0005084_abnormal_gallbladder_morpholo0.94588531
112MP0001324_abnormal_eye_pigmentation0.93293192
113MP0002723_abnormal_immune_serum0.93256135
114MP0003121_genomic_imprinting0.92718196
115MP0005000_abnormal_immune_tolerance0.92142149
116MP0002751_abnormal_autonomic_nervous0.91669142
117MP0001835_abnormal_antigen_presentation0.91583650
118MP0001293_anophthalmia0.91301074
119MP0002734_abnormal_mechanical_nocicepti0.91112780
120MP0003787_abnormal_imprinting0.90598186
121MP0008058_abnormal_DNA_repair0.87162147
122MP0000749_muscle_degeneration0.87111434
123MP0003183_abnormal_peptide_metabolism0.87047718
124MP0002420_abnormal_adaptive_immunity0.87019725
125MP0001819_abnormal_immune_cell0.86688712
126MP0002752_abnormal_somatic_nervous0.86573533
127MP0005025_abnormal_response_to0.86329556
128MP0003137_abnormal_impulse_conducting0.84577918
129MP0002928_abnormal_bile_duct0.84320491
130MP0000689_abnormal_spleen_morphology0.84219968
131MP0002398_abnormal_bone_marrow0.83912615
132MP0001765_abnormal_ion_homeostasis0.82909516
133MP0005332_abnormal_amino_acid0.82139272
134MP0000538_abnormal_urinary_bladder0.81813706
135MP0003136_yellow_coat_color0.80669104
136MP0000566_synostosis0.80593143
137MP0004859_abnormal_synaptic_plasticity0.80479367
138MP0002938_white_spotting0.79977014
139MP0000678_abnormal_parathyroid_gland0.79832822
140MP0001800_abnormal_humoral_immune0.79792605
141MP0001970_abnormal_pain_threshold0.79220036
142MP0000049_abnormal_middle_ear0.79116778
143MP0006276_abnormal_autonomic_nervous0.78990138
144MP0002161_abnormal_fertility/fecundity0.78540770
145MP0001502_abnormal_circadian_rhythm0.77818108
146MP0000631_abnormal_neuroendocrine_gland0.77798197
147MP0001119_abnormal_female_reproductive0.77685226
148MP0000716_abnormal_immune_system0.77674590
149MP0002234_abnormal_pharynx_morphology0.76680611
150MP0003690_abnormal_glial_cell0.75881290
151MP0002419_abnormal_innate_immunity0.75390627
152MP0003866_abnormal_defecation0.75379838
153MP0001764_abnormal_homeostasis0.74851707
154MP0000647_abnormal_sebaceous_gland0.74707126
155MP0001346_abnormal_lacrimal_gland0.74250089
156MP0002452_abnormal_antigen_presenting0.74205115
157MP0001501_abnormal_sleep_pattern0.73973583
158MP0008569_lethality_at_weaning0.73748140
159MP0001545_abnormal_hematopoietic_system0.73591026
160MP0005397_hematopoietic_system_phenotyp0.73591026

Predicted human phenotypes

RankGene SetZ-score
1Type I transferrin isoform profile (HP:0003642)4.65459110
2Increased hepatocellular lipid droplets (HP:0006565)4.30615754
3Mitochondrial inheritance (HP:0001427)4.08984555
4Acute necrotizing encephalopathy (HP:0006965)4.02843511
5Renal Fanconi syndrome (HP:0001994)4.01220291
6Hepatocellular necrosis (HP:0001404)3.97528734
7Hypothermia (HP:0002045)3.90590606
8Lipid accumulation in hepatocytes (HP:0006561)3.89798432
9Thyroid-stimulating hormone excess (HP:0002925)3.77216052
10Increased CSF lactate (HP:0002490)3.69084612
11Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.68497053
12Abnormality of renal resorption (HP:0011038)3.62597611
13Abnormal mitochondria in muscle tissue (HP:0008316)3.62430903
14Attenuation of retinal blood vessels (HP:0007843)3.52883665
15Hepatic necrosis (HP:0002605)3.42648281
16Increased serum pyruvate (HP:0003542)3.35154619
17Abnormality of glycolysis (HP:0004366)3.35154619
18Nephronophthisis (HP:0000090)3.34171714
19Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.32936414
20Abnormal glycosylation (HP:0012345)3.32169961
21Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.32169961
22Abnormal protein N-linked glycosylation (HP:0012347)3.32169961
23Abnormal protein glycosylation (HP:0012346)3.32169961
24Molar tooth sign on MRI (HP:0002419)3.31497380
25Abnormality of midbrain morphology (HP:0002418)3.31497380
26Methylmalonic acidemia (HP:0002912)3.30598846
27Congenital stationary night blindness (HP:0007642)3.22158244
28Progressive macrocephaly (HP:0004481)3.20519397
29Acute encephalopathy (HP:0006846)3.07297035
30Pendular nystagmus (HP:0012043)3.01294120
31Reduced antithrombin III activity (HP:0001976)2.97192648
32Abnormal hair whorl (HP:0010721)2.94420782
33Increased serum lactate (HP:0002151)2.92431788
34Medial flaring of the eyebrow (HP:0010747)2.90651012
35Exertional dyspnea (HP:0002875)2.90522360
36True hermaphroditism (HP:0010459)2.90447614
37Abnormality of the renal medulla (HP:0100957)2.83566992
38Increased intramyocellular lipid droplets (HP:0012240)2.76822875
39Abnormality of cochlea (HP:0000375)2.75742089
40Exercise intolerance (HP:0003546)2.75259078
413-Methylglutaconic aciduria (HP:0003535)2.74537620
42Absent thumb (HP:0009777)2.74002751
43Methylmalonic aciduria (HP:0012120)2.71736585
44Gait imbalance (HP:0002141)2.71670202
45Congenital primary aphakia (HP:0007707)2.71535252
46Aplasia/Hypoplasia of the uvula (HP:0010293)2.70118494
47Severe visual impairment (HP:0001141)2.66809746
48Abnormality of the renal cortex (HP:0011035)2.65637408
49Abnormal rod and cone electroretinograms (HP:0008323)2.65005180
50Nephrogenic diabetes insipidus (HP:0009806)2.62021935
51Bony spicule pigmentary retinopathy (HP:0007737)2.57078977
52Respiratory difficulties (HP:0002880)2.56976061
53Chromsome breakage (HP:0040012)2.55969156
54Lactic acidosis (HP:0003128)2.54222045
55Chromosomal breakage induced by crosslinking agents (HP:0003221)2.52176997
56Patellar aplasia (HP:0006443)2.51676979
57Microvesicular hepatic steatosis (HP:0001414)2.51403947
58Bile duct proliferation (HP:0001408)2.50918733
59Abnormal biliary tract physiology (HP:0012439)2.50918733
60Polydipsia (HP:0001959)2.50271412
61Abnormal drinking behavior (HP:0030082)2.50271412
62Optic disc pallor (HP:0000543)2.48910736
63Type II lissencephaly (HP:0007260)2.48614456
64Cystic liver disease (HP:0006706)2.45839984
65Chronic hepatic failure (HP:0100626)2.45808305
66Abnormality of the ileum (HP:0001549)2.45088494
67Decreased central vision (HP:0007663)2.44687885
68Aplasia/Hypoplasia of the patella (HP:0006498)2.43666552
69Meckel diverticulum (HP:0002245)2.42592316
70Morphological abnormality of the inner ear (HP:0011390)2.39508187
71Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.37778732
72Decreased activity of mitochondrial respiratory chain (HP:0008972)2.37778732
73Abnormality of DNA repair (HP:0003254)2.37346333
74Leukodystrophy (HP:0002415)2.34683723
75Increased muscle lipid content (HP:0009058)2.33174959
76Birth length less than 3rd percentile (HP:0003561)2.28866623
77Abnormal number of erythroid precursors (HP:0012131)2.27816068
78Abnormality of cells of the erythroid lineage (HP:0012130)2.26514098
79Hyperalaninemia (HP:0003348)2.24961892
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.24961892
81Abnormality of alanine metabolism (HP:0010916)2.24961892
82Sclerocornea (HP:0000647)2.21653338
83Rib fusion (HP:0000902)2.20429231
84Decreased electroretinogram (ERG) amplitude (HP:0000654)2.19348185
85Focal motor seizures (HP:0011153)2.18321599
86Respiratory failure (HP:0002878)2.17431501
87Tubular atrophy (HP:0000092)2.16805685
88Renal tubular dysfunction (HP:0000124)2.16635415
89Hyperventilation (HP:0002883)2.15447441
90Decreased lacrimation (HP:0000633)2.14164654
91Cerebral edema (HP:0002181)2.14035622
92Aplasia/hypoplasia of the uterus (HP:0008684)2.13609965
93Pancreatic fibrosis (HP:0100732)2.13299327
94Abnormal respiratory epithelium morphology (HP:0012253)2.12285162
95Abnormal respiratory motile cilium morphology (HP:0005938)2.12285162
96Alacrima (HP:0000522)2.11367503
97Testicular atrophy (HP:0000029)2.09530671
98Abnormality of vitamin B metabolism (HP:0004340)2.08544568
99Anencephaly (HP:0002323)2.06987565
100Vaginal atresia (HP:0000148)2.06924715
101Absent rod-and cone-mediated responses on ERG (HP:0007688)2.06826806
102Abnormality of the renal collecting system (HP:0004742)2.05628645
103Squamous cell carcinoma (HP:0002860)2.04572690
104Polyuria (HP:0000103)2.04268725
105Dynein arm defect of respiratory motile cilia (HP:0012255)2.04122811
106Absent/shortened dynein arms (HP:0200106)2.04122811
107Male pseudohermaphroditism (HP:0000037)2.04081284
108Centrally nucleated skeletal muscle fibers (HP:0003687)2.04035748
109Abnormality of the pons (HP:0007361)2.03444505
110Abnormality of the preputium (HP:0100587)2.03337037
111Hypoplasia of the uterus (HP:0000013)2.03289601
112Muscle hypertrophy of the lower extremities (HP:0008968)2.02288111
113Hypoplastic pelvis (HP:0008839)2.02208521
114Hypoplasia of the pons (HP:0012110)2.00687507
115Congenital hepatic fibrosis (HP:0002612)1.99921532
116Genital tract atresia (HP:0001827)1.99499231
117Poor coordination (HP:0002370)1.99343212
118Epileptic encephalopathy (HP:0200134)1.97998066
119Split foot (HP:0001839)1.97956953
120Abnormality of chromosome stability (HP:0003220)1.97433224
121Abnormality of the vitamin B12 metabolism (HP:0004341)1.97143121
122Opisthotonus (HP:0002179)1.96785324
123Abnormality of urine glucose concentration (HP:0011016)1.95969422
124Glycosuria (HP:0003076)1.95969422
125Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.93971630
126Renal cortical cysts (HP:0000803)1.93497354
127Dyschromatopsia (HP:0007641)1.90029637
128Occipital encephalocele (HP:0002085)1.89154380
129Cerebellar dysplasia (HP:0007033)1.87068041
130Postaxial foot polydactyly (HP:0001830)1.85679252
131Sloping forehead (HP:0000340)1.84811746
132Mesangial abnormality (HP:0001966)1.83936680
133Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.82446488
134Abnormality of the heme biosynthetic pathway (HP:0010472)1.81833158
135Duplicated collecting system (HP:0000081)1.80420376
136Retinal dysplasia (HP:0007973)1.80134766
137Aplasia/Hypoplasia of the tongue (HP:0010295)1.79846220
138Ketosis (HP:0001946)1.79629874
139Hypergonadotropic hypogonadism (HP:0000815)1.78533733
140Neuroendocrine neoplasm (HP:0100634)1.78364157
141Hyperphosphaturia (HP:0003109)1.76757898
142Abnormal urine phosphate concentration (HP:0012599)1.75858649
143Progressive muscle weakness (HP:0003323)1.74854452
144Scanning speech (HP:0002168)1.73547901
145Abnormal ciliary motility (HP:0012262)1.72930122
146Progressive neurologic deterioration (HP:0002344)1.70796598
147Pancytopenia (HP:0001876)1.69792703
148Psychosis (HP:0000709)1.69512372
149Tubulointerstitial nephritis (HP:0001970)1.67433588
150Aplasia/Hypoplasia of the sacrum (HP:0008517)1.65835027
151Abnormal respiratory motile cilium physiology (HP:0012261)1.63351551
152Pancreatic cysts (HP:0001737)1.63017468
153Progressive external ophthalmoplegia (HP:0000590)1.61742207
154Cortical visual impairment (HP:0100704)1.60163166
155Rhinitis (HP:0012384)1.59651573
156Calf muscle hypertrophy (HP:0008981)1.59409259

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK5.45758752
2FRK3.70735769
3MAPKAPK52.80714792
4STK162.65048432
5CASK2.56148657
6TRIM282.36641300
7STK392.26447760
8MAP4K22.25074566
9BMPR1B2.15967152
10EIF2AK32.12561912
11GRK12.03695354
12MKNK11.99116793
13MAP4K11.97730705
14NUAK11.96292656
15MUSK1.95455862
16CDK31.94496735
17TLK11.93850605
18WNK31.92451658
19TXK1.88124413
20TRPM71.86567867
21MAP3K121.86292414
22INSRR1.84987128
23SIK31.82949152
24PIM21.77013430
25ACVR1B1.73839618
26MAP3K41.72774158
27NEK21.61340636
28ERBB31.60529888
29MAPK151.59474834
30OXSR11.58891399
31MAP2K71.55738837
32RAF11.50613590
33VRK11.45466140
34ZAK1.44015911
35MYLK1.41042707
36TEC1.36187020
37PBK1.34971559
38KIT1.34103328
39BMPR21.33010295
40BCR1.32777006
41MST41.32635105
42BCKDK1.29112482
43FES1.26929322
44CAMKK21.25599842
45PLK41.25556443
46KSR11.21541210
47CDK191.14795162
48NTRK31.14560941
49PLK11.14177889
50DYRK21.11003341
51CDC71.10374813
52BRSK21.07907995
53NME21.04884377
54CSNK1G31.04558403
55ATR1.03426971
56WEE11.00778997
57PRPF4B0.99467206
58ADRBK20.98932786
59YES10.98043941
60SYK0.97877277
61VRK20.94583979
62MKNK20.94445025
63DYRK30.89934867
64MAPK130.89261051
65CHEK20.88432756
66EIF2AK20.85350358
67BUB10.84260307
68MAP2K60.83306267
69OBSCN0.82530564
70PKN10.82438099
71PAK30.82178613
72PRKCQ0.80598422
73TTK0.79931928
74PLK30.79900248
75RPS6KA40.79835427
76NME10.78708426
77UHMK10.78093687
78NLK0.77972802
79PRKCI0.77853983
80ADRBK10.77725526
81RIPK40.76614330
82IRAK10.76477715
83TSSK60.76327910
84NEK60.73004242
85SRPK10.72956167
86LCK0.72717532
87WNK40.72602586
88BTK0.72350087
89CAMK2B0.70770077
90LYN0.66184964
91PASK0.63951708
92EPHA40.63628645
93IKBKE0.63461342
94ATM0.63204571
95PNCK0.62379127
96EIF2AK10.59922402
97MARK30.59171969
98MAP2K30.58933629
99CAMK2A0.58927135
100JAK30.58748429
101DAPK10.58624680
102ZAP700.58260229
103RPS6KB20.57941870
104PRKCG0.57860570
105CAMK10.57588366
106RPS6KA50.57271768
107FLT30.56080416
108PIM10.55974865
109AURKB0.55199916
110SIK20.54541710
111PRKD30.54162705
112STK38L0.53911630
113CSNK1G20.53789702
114IKBKB0.52827477
115CLK10.52507791
116HCK0.52098433
117CSNK1A10.50818277
118PHKG20.50613246
119PHKG10.50613246
120CSNK1G10.50343170
121PRKCE0.49640113
122AURKA0.49095724
123LMTK20.48394282
124WNK10.47426658
125CSF1R0.47218133
126TAOK30.47107598
127CCNB10.47099978
128CSNK1D0.47007116
129CSNK1A1L0.45911097
130NEK90.45874515
131PRKAA10.44801401
132IRAK20.43354230
133JAK10.43321433
134PINK10.42513442
135CAMK2D0.41961788
136PTK2B0.40905229
137PLK20.40709038
138IRAK40.40529367
139MAP3K60.39794888
140CSNK2A10.39381795
141TNK20.37758980
142MAPK40.37547636
143MAPK120.37528725
144PDK20.36676817
145PRKG10.36355760
146CHEK10.36349721
147CDK10.35951396
148GRK70.34306186
149CAMK1D0.34247684
150CSNK1E0.34199814
151NEK10.33260285
152CAMK1G0.31885102
153PRKACA0.31785776
154FGFR20.31507814
155DYRK1A0.31064218
156CDK20.30102190
157CSNK2A20.29751794

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030604.11703726
2Oxidative phosphorylation_Homo sapiens_hsa001903.87676754
3Parkinsons disease_Homo sapiens_hsa050122.96569387
4Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.89728129
5Fatty acid elongation_Homo sapiens_hsa000622.86553584
6Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.63652177
7RNA polymerase_Homo sapiens_hsa030202.53504499
8Alzheimers disease_Homo sapiens_hsa050102.48436695
9Ribosome_Homo sapiens_hsa030102.40905057
10Proteasome_Homo sapiens_hsa030502.20550197
11Huntingtons disease_Homo sapiens_hsa050162.19345645
12Sulfur relay system_Homo sapiens_hsa041221.79895364
13Selenocompound metabolism_Homo sapiens_hsa004501.79816950
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.72980648
15DNA replication_Homo sapiens_hsa030301.72442556
16Non-homologous end-joining_Homo sapiens_hsa034501.71581668
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.70249107
18Homologous recombination_Homo sapiens_hsa034401.69580199
19Arachidonic acid metabolism_Homo sapiens_hsa005901.68025762
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66329738
21Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.61699402
22Mismatch repair_Homo sapiens_hsa034301.54292651
23Pyrimidine metabolism_Homo sapiens_hsa002401.42373244
24Nitrogen metabolism_Homo sapiens_hsa009101.40239991
25Collecting duct acid secretion_Homo sapiens_hsa049661.38876706
26Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.34563093
27Ether lipid metabolism_Homo sapiens_hsa005651.33593421
28RNA transport_Homo sapiens_hsa030131.30895476
29Primary immunodeficiency_Homo sapiens_hsa053401.25950368
30Nicotine addiction_Homo sapiens_hsa050331.24427401
31Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.21124365
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.21029704
33Vitamin B6 metabolism_Homo sapiens_hsa007501.19620395
34Purine metabolism_Homo sapiens_hsa002301.17284943
35Serotonergic synapse_Homo sapiens_hsa047261.16589633
36Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.16225277
37Basal transcription factors_Homo sapiens_hsa030221.15959437
38Linoleic acid metabolism_Homo sapiens_hsa005911.15516753
39Nucleotide excision repair_Homo sapiens_hsa034201.15023689
40Vibrio cholerae infection_Homo sapiens_hsa051101.14186710
41Rheumatoid arthritis_Homo sapiens_hsa053231.13806803
42Steroid biosynthesis_Homo sapiens_hsa001001.12170772
43Taste transduction_Homo sapiens_hsa047421.11526904
44Autoimmune thyroid disease_Homo sapiens_hsa053201.10265219
45Sulfur metabolism_Homo sapiens_hsa009201.08446697
46Base excision repair_Homo sapiens_hsa034101.04626326
47Cardiac muscle contraction_Homo sapiens_hsa042601.03255143
48Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.01268892
49Allograft rejection_Homo sapiens_hsa053300.99440893
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.96627292
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.95662952
52alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.92859322
53Olfactory transduction_Homo sapiens_hsa047400.92729701
54N-Glycan biosynthesis_Homo sapiens_hsa005100.90952689
55Metabolic pathways_Homo sapiens_hsa011000.90685468
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87348134
57Tryptophan metabolism_Homo sapiens_hsa003800.87328450
58Morphine addiction_Homo sapiens_hsa050320.87125685
59Regulation of autophagy_Homo sapiens_hsa041400.85931742
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.83660876
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.82126265
62Spliceosome_Homo sapiens_hsa030400.80289966
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.79807824
64Phototransduction_Homo sapiens_hsa047440.78925596
65Maturity onset diabetes of the young_Homo sapiens_hsa049500.78611433
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77195786
67Propanoate metabolism_Homo sapiens_hsa006400.76046551
68RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.75591116
69Circadian rhythm_Homo sapiens_hsa047100.74919606
70Glutamatergic synapse_Homo sapiens_hsa047240.74227663
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.73915240
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72444234
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71719239
74Other glycan degradation_Homo sapiens_hsa005110.69999774
75Steroid hormone biosynthesis_Homo sapiens_hsa001400.68407680
76GABAergic synapse_Homo sapiens_hsa047270.68218054
77Cell cycle_Homo sapiens_hsa041100.67966063
78One carbon pool by folate_Homo sapiens_hsa006700.66384281
79Glutathione metabolism_Homo sapiens_hsa004800.66083096
80Circadian entrainment_Homo sapiens_hsa047130.65125958
81Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63800174
82Hedgehog signaling pathway_Homo sapiens_hsa043400.63642380
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.62058917
84RNA degradation_Homo sapiens_hsa030180.61426239
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.60834990
86Pyruvate metabolism_Homo sapiens_hsa006200.57349712
87Fatty acid metabolism_Homo sapiens_hsa012120.56446875
88Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.52586398
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51647979
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51557998
91Chemical carcinogenesis_Homo sapiens_hsa052040.51454427
92Fat digestion and absorption_Homo sapiens_hsa049750.51253660
93Cysteine and methionine metabolism_Homo sapiens_hsa002700.51005980
94p53 signaling pathway_Homo sapiens_hsa041150.49889748
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.49496276
96Primary bile acid biosynthesis_Homo sapiens_hsa001200.49053568
97Arginine and proline metabolism_Homo sapiens_hsa003300.48656695
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.48199660
99Fanconi anemia pathway_Homo sapiens_hsa034600.46227176
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.45137849
101Peroxisome_Homo sapiens_hsa041460.43347540
102Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.43088890
103Type I diabetes mellitus_Homo sapiens_hsa049400.42795006
104Synaptic vesicle cycle_Homo sapiens_hsa047210.41634597
105Herpes simplex infection_Homo sapiens_hsa051680.39964809
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.39496002
107Caffeine metabolism_Homo sapiens_hsa002320.39135868
108Lysine degradation_Homo sapiens_hsa003100.38955557
109Retinol metabolism_Homo sapiens_hsa008300.38704974
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38674596
111Phagosome_Homo sapiens_hsa041450.38314622
112Ovarian steroidogenesis_Homo sapiens_hsa049130.37904625
113Hematopoietic cell lineage_Homo sapiens_hsa046400.37062347
114Asthma_Homo sapiens_hsa053100.36934082
115Sphingolipid metabolism_Homo sapiens_hsa006000.36635041
116Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36404542
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35569161
118Alcoholism_Homo sapiens_hsa050340.35531972
119Folate biosynthesis_Homo sapiens_hsa007900.34686892
120Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.34539085
121Cyanoamino acid metabolism_Homo sapiens_hsa004600.34519493
122ABC transporters_Homo sapiens_hsa020100.34369282
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.34025016
124Long-term depression_Homo sapiens_hsa047300.33489497
125Insulin secretion_Homo sapiens_hsa049110.32689518
126mRNA surveillance pathway_Homo sapiens_hsa030150.31642743
127Phosphatidylinositol signaling system_Homo sapiens_hsa040700.31486334
128Butanoate metabolism_Homo sapiens_hsa006500.31351458
129Epstein-Barr virus infection_Homo sapiens_hsa051690.29703620
130beta-Alanine metabolism_Homo sapiens_hsa004100.29334812

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