IGFBP5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pattern specification involved in kidney development (GO:0061004)5.24625718
2extracellular matrix assembly (GO:0085029)4.81646688
3skin morphogenesis (GO:0043589)4.58430454
4glomerular basement membrane development (GO:0032836)4.42912400
5hemidesmosome assembly (GO:0031581)4.18266369
6sequestering of extracellular ligand from receptor (GO:0035581)4.15416608
7glomerular visceral epithelial cell development (GO:0072015)4.01048391
8glomerular epithelial cell development (GO:0072310)3.84285351
9* type B pancreatic cell proliferation (GO:0044342)3.81285075
10extracellular fibril organization (GO:0043206)3.67959654
11peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.61824474
12planar cell polarity pathway involved in neural tube closure (GO:0090179)3.57265528
13virion attachment to host cell (GO:0019062)3.51192692
14adhesion of symbiont to host cell (GO:0044650)3.51192692
15lung vasculature development (GO:0060426)3.50140327
16endocardial cushion morphogenesis (GO:0003203)3.44593988
17hippo signaling (GO:0035329)3.44103662
18growth hormone receptor signaling pathway (GO:0060396)3.42992963
19regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.41691238
20cytoskeletal anchoring at plasma membrane (GO:0007016)3.40250190
21cellular response to vitamin (GO:0071295)3.35195755
22insulin-like growth factor receptor signaling pathway (GO:0048009)3.34998518
23polarized epithelial cell differentiation (GO:0030859)3.34876575
24dermatan sulfate biosynthetic process (GO:0030208)3.30202096
25paraxial mesoderm development (GO:0048339)3.30164479
26dermatan sulfate metabolic process (GO:0030205)3.28177958
27embryonic retina morphogenesis in camera-type eye (GO:0060059)3.26584347
28negative regulation of osteoblast proliferation (GO:0033689)3.23093684
29protein heterotrimerization (GO:0070208)3.22919891
30negative regulation of fatty acid transport (GO:2000192)3.21723845
31tooth mineralization (GO:0034505)3.21577237
32fibril organization (GO:0097435)3.20236786
33renal filtration (GO:0097205)3.19676218
34atrioventricular valve morphogenesis (GO:0003181)3.18595273
35proximal/distal pattern formation (GO:0009954)3.18438522
36neuron projection extension involved in neuron projection guidance (GO:1902284)3.16243675
37axon extension involved in axon guidance (GO:0048846)3.16243675
38metanephric mesenchyme development (GO:0072075)3.15810120
39regulation of extracellular matrix disassembly (GO:0010715)3.15468242
40pericardium development (GO:0060039)3.14527978
41epithelial cell-cell adhesion (GO:0090136)3.14150340
42positive regulation of endothelial cell apoptotic process (GO:2000353)3.12797139
43branching involved in salivary gland morphogenesis (GO:0060445)3.12395091
44adhesion of symbiont to host (GO:0044406)3.10410952
45establishment of apical/basal cell polarity (GO:0035089)3.10363654
46glomerulus development (GO:0032835)3.07760261
47venous blood vessel morphogenesis (GO:0048845)3.07667411
48keratan sulfate catabolic process (GO:0042340)3.07536468
49cellular response to growth hormone stimulus (GO:0071378)3.04051115
50cell adhesion mediated by integrin (GO:0033627)3.03466787
51outer ear morphogenesis (GO:0042473)3.02134383
52mesenchyme morphogenesis (GO:0072132)2.99795190
53muscle cell migration (GO:0014812)2.99645650
54regulation of cardioblast differentiation (GO:0051890)2.98398977
55heart valve morphogenesis (GO:0003179)2.98158528
56blood vessel maturation (GO:0001955)2.98105172
57endothelial cell morphogenesis (GO:0001886)2.97973091
58glomerular filtration (GO:0003094)2.96691427
59cardiac muscle cell proliferation (GO:0060038)2.93055374
60camera-type eye morphogenesis (GO:0048593)2.92534698
61apoptotic cell clearance (GO:0043277)2.92337534
62retina vasculature morphogenesis in camera-type eye (GO:0061299)2.92216323
63basement membrane organization (GO:0071711)2.91792884
64collagen fibril organization (GO:0030199)2.90528242
65kidney mesenchyme development (GO:0072074)2.90216476
66renal system development (GO:0072001)2.89841117
67segment specification (GO:0007379)2.89377434
68G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.88588867
69extracellular matrix organization (GO:0030198)2.87800139
70extracellular structure organization (GO:0043062)2.87400564
71regulation of axon extension involved in axon guidance (GO:0048841)2.85641938
72regulation of response to osmotic stress (GO:0047484)2.83899446
73regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.83805860
74COPI coating of Golgi vesicle (GO:0048205)2.82706593
75Golgi transport vesicle coating (GO:0048200)2.82706593
76collecting duct development (GO:0072044)2.81663730
77regulation of cardioblast proliferation (GO:0003264)2.80409639
78regulation of secondary heart field cardioblast proliferation (GO:0003266)2.80409639
79cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.79625177
80regulation of cell fate specification (GO:0042659)2.79430932
81cell migration involved in sprouting angiogenesis (GO:0002042)2.78850869
82mesodermal cell differentiation (GO:0048333)2.78348074
83smooth muscle tissue development (GO:0048745)2.77902200
84regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.77594577
85gastrulation with mouth forming second (GO:0001702)2.76470603
86hypotonic response (GO:0006971)2.76212911
87barbed-end actin filament capping (GO:0051016)2.76056182
88negative regulation of chondrocyte differentiation (GO:0032331)2.74659072
89negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.74139492
90positive regulation of blood vessel endothelial cell migration (GO:0043536)2.74099588
91positive regulation of mesenchymal cell proliferation (GO:0002053)2.73445276
92positive regulation of histone deacetylation (GO:0031065)2.72949057
93regulation of axon guidance (GO:1902667)2.72865618
94adherens junction assembly (GO:0034333)2.72760227
95cochlea morphogenesis (GO:0090103)2.69870340
96heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.69762434
97regulation of heart morphogenesis (GO:2000826)2.69706464
98chondrocyte development (GO:0002063)2.69640292
99endocardial cushion development (GO:0003197)2.69544290
100coronary vasculature morphogenesis (GO:0060977)2.68855584
101endodermal cell differentiation (GO:0035987)2.68618372
102respiratory tube development (GO:0030323)2.68498910
103collagen metabolic process (GO:0032963)2.67827096
104dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.67256965
105cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.67145365
106collagen catabolic process (GO:0030574)2.65711565
107bone morphogenesis (GO:0060349)2.65301227
108heart valve formation (GO:0003188)2.64829743
109midgut development (GO:0007494)2.64497564
110epithelial cell differentiation involved in prostate gland development (GO:0060742)2.64307760
111cell-substrate junction assembly (GO:0007044)2.64180933
112focal adhesion assembly (GO:0048041)2.64180543
113cell-substrate adherens junction assembly (GO:0007045)2.64180543
114chondrocyte proliferation (GO:0035988)2.63767322
115plasma membrane repair (GO:0001778)2.62885238
116regulation of integrin-mediated signaling pathway (GO:2001044)2.62721805
117multicellular organismal macromolecule metabolic process (GO:0044259)2.62652424
118protein retention in ER lumen (GO:0006621)2.62271542
119non-canonical Wnt signaling pathway (GO:0035567)2.61221015
120Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.61095006
121aorta morphogenesis (GO:0035909)2.60329930
122somatic stem cell division (GO:0048103)2.59463132
123morphogenesis of an epithelial sheet (GO:0002011)2.58934407
124negative regulation of embryonic development (GO:0045992)2.58379875
125protein localization to cell surface (GO:0034394)2.58000914
126extracellular regulation of signal transduction (GO:1900115)2.57536345
127extracellular negative regulation of signal transduction (GO:1900116)2.57536345
128neuromuscular junction development (GO:0007528)2.57514401
129positive regulation of fibroblast migration (GO:0010763)2.57496306
130negative regulation of cell fate specification (GO:0009996)2.56291509
131mesenchymal-epithelial cell signaling (GO:0060638)2.56239208
132negative regulation of catenin import into nucleus (GO:0035414)2.56108024
133negative regulation of axon extension involved in axon guidance (GO:0048843)2.56087389
134heparan sulfate proteoglycan metabolic process (GO:0030201)2.56005357
135regulation of establishment of planar polarity (GO:0090175)2.55796331
136regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.55669874
137lung-associated mesenchyme development (GO:0060484)2.55504486
138Notch signaling involved in heart development (GO:0061314)2.55381509
139bone trabecula formation (GO:0060346)2.55332710
140* negative regulation of smooth muscle cell migration (GO:0014912)2.54882896
141lung lobe morphogenesis (GO:0060463)2.54587117
142vascular endothelial growth factor signaling pathway (GO:0038084)2.54486952
143establishment of monopolar cell polarity (GO:0061162)2.54333561
144establishment or maintenance of monopolar cell polarity (GO:0061339)2.54333561
145vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.52979630
146regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.52965236
147convergent extension (GO:0060026)2.52946936
148positive regulation of epithelial to mesenchymal transition (GO:0010718)2.51980403
149dorsal/ventral axis specification (GO:0009950)2.51500506
150multicellular organismal catabolic process (GO:0044243)2.50834510
151desmosome organization (GO:0002934)2.50817727
152myoblast fusion (GO:0007520)2.50794500
153epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.49548362
154regulation of mesenchymal cell proliferation (GO:0010464)2.48555575
155substrate adhesion-dependent cell spreading (GO:0034446)2.48437215
156extracellular matrix disassembly (GO:0022617)2.47927012
157ectoderm development (GO:0007398)2.47029026
158cell migration involved in heart development (GO:0060973)2.46529847
159multicellular organismal metabolic process (GO:0044236)2.45722433
160protein targeting to plasma membrane (GO:0072661)2.45307446
161semaphorin-plexin signaling pathway (GO:0071526)2.44860382

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.11299526
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.09927590
3ZNF263_19887448_ChIP-Seq_K562_Human2.84758222
4ESR2_21235772_ChIP-Seq_MCF-7_Human2.53128961
5RARG_19884340_ChIP-ChIP_MEFs_Mouse2.51928320
6ESR1_21235772_ChIP-Seq_MCF-7_Human2.48963132
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.43244196
8CLOCK_20551151_ChIP-Seq_293T_Human2.32538280
9WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.29315196
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.20010442
11EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.17073238
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.11286445
13ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.09540193
14ZNF217_24962896_ChIP-Seq_MCF-7_Human2.07356632
15CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.98135462
16SMAD_19615063_ChIP-ChIP_OVARY_Human1.97239346
17* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.96006710
18* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.96006710
19EP300_21415370_ChIP-Seq_HL-1_Mouse1.91715568
20ESR1_20079471_ChIP-ChIP_T-47D_Human1.80412451
21* SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.80222436
22STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.79739449
23* AHR_22903824_ChIP-Seq_MCF-7_Human1.69179639
24NRF2_20460467_ChIP-Seq_MEFs_Mouse1.68871919
25NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.68871919
26* SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.66010411
27* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.65715205
28ERG_21242973_ChIP-ChIP_JURKAT_Human1.64955001
29* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.63379693
30* EED_16625203_ChIP-ChIP_MESCs_Mouse1.63245113
31TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.62008520
32SOX9_24532713_ChIP-Seq_HFSC_Mouse1.61200231
33* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.57143809
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.51297523
35* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.50985080
36* RNF2_27304074_Chip-Seq_ESCs_Mouse1.50697948
37* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.46297863
38ISL1_27105846_Chip-Seq_CPCs_Mouse1.45120871
39EZH2_22144423_ChIP-Seq_EOC_Human1.44543019
40* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.44523554
41* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.44212734
42* ARNT_22903824_ChIP-Seq_MCF-7_Human1.44021724
43* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.43836162
44* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.43807783
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.43535227
46AR_21572438_ChIP-Seq_LNCaP_Human1.42690934
47* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.41330275
48PPAR_26484153_Chip-Seq_NCI-H1993_Human1.41313444
49HIF1A_21447827_ChIP-Seq_MCF-7_Human1.40867640
50TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.40618437
51* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.39606771
52* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.38353689
53KDM2B_26808549_Chip-Seq_K562_Human1.38304128
54PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.37356438
55TP53_16413492_ChIP-PET_HCT116_Human1.36528743
56SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.36350371
57* CJUN_26792858_Chip-Seq_BT549_Human1.34745734
58EGR1_19374776_ChIP-ChIP_THP-1_Human1.34423387
59* EZH2_27304074_Chip-Seq_ESCs_Mouse1.34031393
60* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.33442122
61* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.33061384
62* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.32262482
63KDM2B_26808549_Chip-Seq_SUP-B15_Human1.31471182
64* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.29695378
65FOXO3_23340844_ChIP-Seq_DLD1_Human1.29326840
66* SA1_22415368_ChIP-Seq_MEFs_Mouse1.28934085
67* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.28081146
68* EZH2_27294783_Chip-Seq_ESCs_Mouse1.27756283
69TBX20_22328084_ChIP-Seq_HEART_Mouse1.26372594
70TBX20_22080862_ChIP-Seq_HEART_Mouse1.26372594
71* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.25180099
72SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.24957068
73* TP53_20018659_ChIP-ChIP_R1E_Mouse1.24423784
74RUNX1_27514584_Chip-Seq_MCF-7_Human1.24046232
75STAT6_21828071_ChIP-Seq_BEAS2B_Human1.23487851
76TP53_22127205_ChIP-Seq_IMR90_Human1.22792371
77ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.22293416
78TP53_23651856_ChIP-Seq_MEFs_Mouse1.20198914
79RACK7_27058665_Chip-Seq_MCF-7_Human1.19950866
80P300_27058665_Chip-Seq_ZR-75-30cells_Human1.19822567
81ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18671385
82* RING1B_27294783_Chip-Seq_ESCs_Mouse1.15075267
83* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.13804935
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.12686479
85LXR_22292898_ChIP-Seq_THP-1_Human1.11647153
86* RING1B_27294783_Chip-Seq_NPCs_Mouse1.09966767
87SOX2_20726797_ChIP-Seq_SW620_Human1.09541025
88DROSHA_22980978_ChIP-Seq_HELA_Human1.09126295
89TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.07679435
90CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07374489
91CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.06946995
92NFIB_24661679_ChIP-Seq_LUNG_Mouse1.06007425
93GATA2_21666600_ChIP-Seq_HMVEC_Human1.04927117
94KLF5_25053715_ChIP-Seq_YYC3_Human1.04638452
95BRD4_25478319_ChIP-Seq_HGPS_Human1.04591475
96THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04423321
97ELK3_25401928_ChIP-Seq_HUVEC_Human1.02936744
98CDX2_20551321_ChIP-Seq_CACO-2_Human1.02870436
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.02706030
100MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.02104910
101* TP53_18474530_ChIP-ChIP_U2OS_Human1.01793070
102* KDM2B_26808549_Chip-Seq_DND41_Human1.01701838
103SALL4_18804426_ChIP-ChIP_XEN_Mouse1.01504430
104GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.01490580
105JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01351985
106* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.01305232
107TCF4_18268006_ChIP-ChIP_LS174T_Human1.00701219
108SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.00649001
109SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.00510281
110UBF1/2_26484160_Chip-Seq_HMECs_Human1.00071809
111PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99808597
112* KDM2B_26808549_Chip-Seq_JURKAT_Human0.98963742
113ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.98350150
114NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97917633
115CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.97160446
116* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96880360
117ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.96043548
118CTNNB1_20460455_ChIP-Seq_HCT116_Human0.95917444
119TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95075441
120TET1_21490601_ChIP-Seq_MESCs_Mouse0.94577300
121EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93969307
122SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.93826382

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004272_abnormal_basement_membrane3.43913822
2MP0010234_abnormal_vibrissa_follicle3.35735687
3MP0005257_abnormal_intraocular_pressure3.26962986
4MP0005623_abnormal_meninges_morphology2.82381685
5MP0008438_abnormal_cutaneous_collagen2.79056174
6MP0003705_abnormal_hypodermis_morpholog2.65778119
7MP0005503_abnormal_tendon_morphology2.65002983
8MP0001542_abnormal_bone_strength2.40660850
9MP0005275_abnormal_skin_tensile2.30904388
10MP0003942_abnormal_urinary_system2.22219996
11MP0000534_abnormal_ureter_morphology2.15073805
12MP0000537_abnormal_urethra_morphology2.04696801
13MP0004084_abnormal_cardiac_muscle2.02638269
14MP0001849_ear_inflammation2.01285302
15MP0003566_abnormal_cell_adhesion1.99495762
16MP0010030_abnormal_orbit_morphology1.90824146
17MP0002295_abnormal_pulmonary_circulatio1.89379794
18MP0000751_myopathy1.86384734
19MP0002254_reproductive_system_inflammat1.85069697
20MP0000566_synostosis1.84681039
21MP0000733_abnormal_muscle_development1.80545517
22MP0002282_abnormal_trachea_morphology1.78604471
23MP0009384_cardiac_valve_regurgitation1.73809050
24MP0005377_hearing/vestibular/ear_phenot1.69342017
25MP0003878_abnormal_ear_physiology1.69342017
26MP0004885_abnormal_endolymph1.69069310
27MP0009053_abnormal_anal_canal1.68529501
28MP0005248_abnormal_Harderian_gland1.64319885
29MP0004858_abnormal_nervous_system1.58008050
30MP0003385_abnormal_body_wall1.57929481
31MP0001299_abnormal_eye_distance/1.57056485
32MP0000762_abnormal_tongue_morphology1.56398714
33MP0005076_abnormal_cell_differentiation1.55587102
34MP0003115_abnormal_respiratory_system1.55449774
35MP0001881_abnormal_mammary_gland1.52728709
36MP0002896_abnormal_bone_mineralization1.52441287
37MP0002108_abnormal_muscle_morphology1.50936024
38MP0000750_abnormal_muscle_regeneration1.49911204
39MP0003941_abnormal_skin_development1.47576698
40MP0001348_abnormal_lacrimal_gland1.47250565
41MP0003300_gastrointestinal_ulcer1.46272882
42MP0005508_abnormal_skeleton_morphology1.43778937
43MP0003279_aneurysm1.42306282
44MP0010678_abnormal_skin_adnexa1.40857410
45MP0000767_abnormal_smooth_muscle1.37210612
46MP0009250_abnormal_appendicular_skeleto1.35896518
47MP0009780_abnormal_chondrocyte_physiolo1.35073749
48MP0003950_abnormal_plasma_membrane1.30939375
49MP0004087_abnormal_muscle_fiber1.30909851
50MP0003283_abnormal_digestive_organ1.30792500
51MP0002249_abnormal_larynx_morphology1.30642748
52MP0000428_abnormal_craniofacial_morphol1.29946535
53MP0001243_abnormal_dermal_layer1.27197419
54MP0002932_abnormal_joint_morphology1.27116828
55MP0000579_abnormal_nail_morphology1.25072509
56MP0001346_abnormal_lacrimal_gland1.24620167
57MP0001958_emphysema1.24023753
58MP0000013_abnormal_adipose_tissue1.23076339
59MP0010368_abnormal_lymphatic_system1.22880181
60MP0003091_abnormal_cell_migration1.20438577
61MP0002233_abnormal_nose_morphology1.19847064
62MP0005595_abnormal_vascular_smooth1.19408780
63MP0010630_abnormal_cardiac_muscle1.19349650
64MP0005390_skeleton_phenotype1.18379333
65MP0003935_abnormal_craniofacial_develop1.16276976
66MP0000163_abnormal_cartilage_morphology1.15734876
67MP0002234_abnormal_pharynx_morphology1.15000090
68MP0003755_abnormal_palate_morphology1.12403132
69MP0003045_fibrosis1.12402926
70MP0000516_abnormal_urinary_system1.09812137
71MP0005367_renal/urinary_system_phenotyp1.09812137
72MP0004264_abnormal_extraembryonic_tissu1.08139129
73MP0004036_abnormal_muscle_relaxation1.07451810
74MP0010386_abnormal_urinary_bladder1.05888647
75MP0001485_abnormal_pinna_reflex1.05670820
76MP0005187_abnormal_penis_morphology1.04026514
77MP0002116_abnormal_craniofacial_bone1.03479226
78MP0006054_spinal_hemorrhage1.00957791
79MP0002877_abnormal_melanocyte_morpholog1.00436943
80MP0003567_abnormal_fetal_cardiomyocyte0.99484139
81MP0003879_abnormal_hair_cell0.99140718
82MP0002106_abnormal_muscle_physiology0.99096268
83MP0002115_abnormal_skeleton_extremities0.98975726
84MP0005369_muscle_phenotype0.98777066
85MP0002060_abnormal_skin_morphology0.97632282
86MP0002925_abnormal_cardiovascular_devel0.96951371
87MP0004233_abnormal_muscle_weight0.96830712
88MP0003122_maternal_imprinting0.95989207
89MP0001879_abnormal_lymphatic_vessel0.95855070
90MP0000049_abnormal_middle_ear0.94948525
91MP0002089_abnormal_postnatal_growth/wei0.94846522
92MP0003937_abnormal_limbs/digits/tail_de0.93810220
93MP0000462_abnormal_digestive_system0.93789516
94MP0001270_distended_abdomen0.93534027
95MP0000383_abnormal_hair_follicle0.93377474
96MP0009278_abnormal_bone_marrow0.92421731
97MP0002938_white_spotting0.91032907
98MP0005164_abnormal_response_to0.90913633
99MP0000759_abnormal_skeletal_muscle0.90539558
100MP0000467_abnormal_esophagus_morphology0.89404177
101MP0000432_abnormal_head_morphology0.89365912
102MP0004145_abnormal_muscle_electrophysio0.88938846
103MP0001340_abnormal_eyelid_morphology0.86489212
104MP0000747_muscle_weakness0.85984276
105MP0000749_muscle_degeneration0.85974623
106MP0002933_joint_inflammation0.85972306
107MP0002653_abnormal_ependyma_morphology0.85829978
108MP0006138_congestive_heart_failure0.85562192
109MP0002128_abnormal_blood_circulation0.85263893
110MP0005620_abnormal_muscle_contractility0.84997199
111MP0010352_gastrointestinal_tract_polyps0.84588842
112MP0005197_abnormal_uvea_morphology0.84417357
113MP0005023_abnormal_wound_healing0.84079609
114MP0002972_abnormal_cardiac_muscle0.83771522
115MP0000538_abnormal_urinary_bladder0.82750468
116MP0002837_dystrophic_cardiac_calcinosis0.82600794
117MP0002796_impaired_skin_barrier0.81581040
118MP0008004_abnormal_stomach_pH0.81533449
119MP0002113_abnormal_skeleton_development0.71283249
120MP0001614_abnormal_blood_vessel0.70262725
121MP0002133_abnormal_respiratory_system0.70077571
122MP0005388_respiratory_system_phenotype0.70077571
123MP0001175_abnormal_lung_morphology0.68170087
124MP0003448_altered_tumor_morphology0.66990061
125MP0004883_abnormal_blood_vessel0.66128317
126MP0000681_abnormal_thyroid_gland0.62858712
127MP0002998_abnormal_bone_remodeling0.62164105
128MP0000613_abnormal_salivary_gland0.62043799
129MP0003795_abnormal_bone_structure0.61754112
130MP0005171_absent_coat_pigmentation0.59845963
131MP0004134_abnormal_chest_morphology0.59759933
132MP0002114_abnormal_axial_skeleton0.59197553
133MP0005409_darkened_coat_color0.58295055
134MP0002168_other_aberrant_phenotype0.58032855
135MP0000003_abnormal_adipose_tissue0.57387029

Predicted human phenotypes

RankGene SetZ-score
1Follicular hyperkeratosis (HP:0007502)4.62867751
2Soft skin (HP:0000977)4.51864196
3Shallow orbits (HP:0000586)4.32204526
4Abnormality of dentin (HP:0010299)3.98257135
5Broad metatarsal (HP:0001783)3.78858561
6Right ventricular cardiomyopathy (HP:0011663)3.77402373
7Cervical subluxation (HP:0003308)3.74369041
8Atrophic scars (HP:0001075)3.64067402
9Wormian bones (HP:0002645)3.62917377
10Type 1 muscle fiber predominance (HP:0003803)3.46415939
11Protrusio acetabuli (HP:0003179)3.41812712
12Ankle contracture (HP:0006466)3.31457154
13Genu recurvatum (HP:0002816)3.17174698
14Bowel diverticulosis (HP:0005222)3.11372611
15Peritonitis (HP:0002586)3.08375083
16Pterygium (HP:0001059)3.05563901
17Wide anterior fontanel (HP:0000260)2.96451434
18Premature rupture of membranes (HP:0001788)2.95445326
19Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.92007061
20Hypoplastic ischia (HP:0003175)2.91630588
21Biconcave vertebral bodies (HP:0004586)2.90482932
22Joint laxity (HP:0001388)2.88112645
23Spondylolisthesis (HP:0003302)2.86744084
24Vertebral compression fractures (HP:0002953)2.84896078
25Hypoventilation (HP:0002791)2.82701082
26Exostoses (HP:0100777)2.79233869
27Aortic dissection (HP:0002647)2.71369772
28Milia (HP:0001056)2.69452963
29Aortic regurgitation (HP:0001659)2.68494813
30Cerebral aneurysm (HP:0004944)2.65122241
31Popliteal pterygium (HP:0009756)2.64099202
32Arterial tortuosity (HP:0005116)2.61979629
33Aplasia of the musculature (HP:0100854)2.61375045
34Focal segmental glomerulosclerosis (HP:0000097)2.60772080
35Abnormality of the ischium (HP:0003174)2.55936367
36Aortic aneurysm (HP:0004942)2.55254720
37Mitral regurgitation (HP:0001653)2.52826595
38Elbow flexion contracture (HP:0002987)2.51281122
39Vascular tortuosity (HP:0004948)2.41173804
40Fragile skin (HP:0001030)2.38619194
41Mildly elevated creatine phosphokinase (HP:0008180)2.36020607
42Scapular winging (HP:0003691)2.35525481
43Turricephaly (HP:0000262)2.35163437
44Humeroradial synostosis (HP:0003041)2.32447876
45Synostosis involving the elbow (HP:0003938)2.32447876
46Hypoplasia of the iris (HP:0007676)2.29282766
47Overgrowth (HP:0001548)2.27415595
48Increased connective tissue (HP:0009025)2.25900030
49Germ cell neoplasia (HP:0100728)2.25857757
50Bell-shaped thorax (HP:0001591)2.21070688
51Enlarged penis (HP:0000040)2.19845670
52Osteolytic defects of the phalanges of the hand (HP:0009771)2.19348805
53Osteolytic defects of the hand bones (HP:0009699)2.19348805
54Increased variability in muscle fiber diameter (HP:0003557)2.18429048
55Bronchomalacia (HP:0002780)2.16743911
56Abnormality of the acetabulum (HP:0003170)2.16208487
57Long toe (HP:0010511)2.15492905
58Abnormal delivery (HP:0001787)2.14468237
59Abnormality of the 4th metacarpal (HP:0010012)2.13720164
60Ulnar bowing (HP:0003031)2.11374826
61Aneurysm (HP:0002617)2.09874041
62Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.09527499
63Short 4th metacarpal (HP:0010044)2.09527499
64Mitral valve prolapse (HP:0001634)2.08352259
65Glomerulosclerosis (HP:0000096)2.07216464
66Abnormality of skeletal muscle fiber size (HP:0012084)2.07127512
67Infantile muscular hypotonia (HP:0008947)2.06281493
68Buphthalmos (HP:0000557)2.05834559
69Mild short stature (HP:0003502)2.05221240
70Breech presentation (HP:0001623)2.04175742
71Thin ribs (HP:0000883)2.04046407
72Aortic valve stenosis (HP:0001650)2.03958970
73Protruding ear (HP:0000411)2.03556713
74Coronal craniosynostosis (HP:0004440)2.03447141
75Hip contracture (HP:0003273)2.03418196
76Mesomelia (HP:0003027)2.01726859
77Epiphyseal dysplasia (HP:0002656)2.01141665
78Abnormality of the anterior chamber (HP:0000593)1.98863916
79Difficulty running (HP:0009046)1.97128865
80Urethral obstruction (HP:0000796)1.96007409
81Blue sclerae (HP:0000592)1.95818954
82Spinal rigidity (HP:0003306)1.95364326
83Obstructive sleep apnea (HP:0002870)1.95100359
84Ectopia lentis (HP:0001083)1.94942418
85Joint stiffness (HP:0001387)1.94808362
86Tarsal synostosis (HP:0008368)1.92654074
87Limb-girdle muscle weakness (HP:0003325)1.92568954
88Bladder diverticulum (HP:0000015)1.92411105
89Disproportionate tall stature (HP:0001519)1.91913598
90Calcaneovalgus deformity (HP:0001848)1.91547745
91Lymphangioma (HP:0100764)1.90985825
92Absent frontal sinuses (HP:0002688)1.90715062
93Deformed tarsal bones (HP:0008119)1.89462742
94Inguinal hernia (HP:0000023)1.88631082
95Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.88342861
96Renal duplication (HP:0000075)1.88156933
97Abnormality of the pubic bones (HP:0003172)1.88145168
98Fetal akinesia sequence (HP:0001989)1.88121826
99Aplasia cutis congenita (HP:0001057)1.87364240
100Morphological abnormality of the middle ear (HP:0008609)1.86261640
101Wrist flexion contracture (HP:0001239)1.86259450
102Generalized amyotrophy (HP:0003700)1.85444270
103Natal tooth (HP:0000695)1.84969899
104Anterior segment dysgenesis (HP:0007700)1.82895561
105Pili torti (HP:0003777)1.82772942
106Hyporeflexia of lower limbs (HP:0002600)1.82511288
107Deviation of the hallux (HP:0010051)1.81262765
108Hydroureter (HP:0000072)1.81202591
109Round ear (HP:0100830)1.81162627
110Muscle fiber splitting (HP:0003555)1.80740180
111Premature skin wrinkling (HP:0100678)1.79553696
112Nonimmune hydrops fetalis (HP:0001790)1.78366211
113Choanal stenosis (HP:0000452)1.77975675
114Neonatal short-limb short stature (HP:0008921)1.77910681
115Thoracolumbar scoliosis (HP:0002944)1.77705883
116Muscle fiber inclusion bodies (HP:0100299)1.77400124
117Vitreoretinal degeneration (HP:0000655)1.77332909
118Severe Myopia (HP:0011003)1.76083471
119Ovoid vertebral bodies (HP:0003300)1.75169620
120Subacute progressive viral hepatitis (HP:0006572)1.75061337
121Knee flexion contracture (HP:0006380)1.74923836
122Abnormality of skull ossification (HP:0002703)1.74465906
123Broad long bones (HP:0005622)1.74227498
124Difficulty climbing stairs (HP:0003551)1.73732309
125Achilles tendon contracture (HP:0001771)1.72609384
126Limited hip movement (HP:0008800)1.72295050
127Hallux valgus (HP:0001822)1.70923953
128Persistence of primary teeth (HP:0006335)1.70788376
129Pulmonary artery stenosis (HP:0004415)1.70688611
130Mesangial abnormality (HP:0001966)1.70677617
131Aplasia involving bones of the upper limbs (HP:0009823)1.70018804
132Aplasia of the phalanges of the hand (HP:0009802)1.70018804
133Aplasia involving bones of the extremities (HP:0009825)1.70018804
134Synostosis involving bones of the lower limbs (HP:0009138)1.69749648
135Synostosis involving bones of the feet (HP:0009140)1.69749648
136Osteopenia (HP:0000938)1.69615567
137Ulnar deviation of the wrist (HP:0003049)1.69593427
138Hepatoblastoma (HP:0002884)1.68442236
139Cupped ribs (HP:0000887)1.68432498
140Thin bony cortex (HP:0002753)1.67769224
141Asymmetry of the thorax (HP:0001555)1.67372478
142Coxa vara (HP:0002812)1.66397182
143Abnormality of the calf musculature (HP:0001430)1.65585351
144Flared iliac wings (HP:0002869)1.65500505
145Nemaline bodies (HP:0003798)1.65303187
146Asymmetric septal hypertrophy (HP:0001670)1.65286478
147Osteoarthritis (HP:0002758)1.65094756
148Short nail (HP:0001799)1.65086000
149Dilatation of the ascending aorta (HP:0005111)1.64935859
150Slender build (HP:0001533)1.64132732
151Mitral stenosis (HP:0001718)1.64008795
152Onycholysis (HP:0001806)1.63979958
153Striae distensae (HP:0001065)1.63561292
154Hyperextensible skin (HP:0000974)1.63398368
155Abnormality of the humeroradial joint (HP:0100744)1.62833080
156Trigonocephaly (HP:0000243)1.62464495
157Short hallux (HP:0010109)1.62424910
158Camptodactyly of toe (HP:0001836)1.61862671
159Rectal prolapse (HP:0002035)1.61673585
160Distal upper limb amyotrophy (HP:0007149)1.61296847
161Advanced eruption of teeth (HP:0006288)1.61249809

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SIK15.99001038
2DDR23.58107166
3LATS13.49432883
4TRIB33.29449677
5EPHA32.52508210
6FER2.44001297
7RIPK12.41455660
8PDGFRA2.38374349
9EPHB12.37900952
10WNK42.33289795
11PKN22.23408861
12EPHB22.21429543
13NEK92.19360786
14TTN2.10575835
15GRK12.05503396
16TESK12.01851220
17AKT32.01013035
18GRK51.98917637
19MATK1.80969048
20PIK3CA1.78075341
21GRK71.77345166
22PTK61.76531630
23CAMK1G1.70372495
24LATS21.65272365
25STK391.64005310
26LIMK11.54631088
27TGFBR21.42250764
28PRKD21.41431539
29BMX1.41109879
30FGFR41.40942578
31ADRBK21.38079458
32FGFR11.37510914
33RET1.36511693
34ERBB41.36223044
35LMTK21.33951147
36PAK41.33803164
37ADRBK11.31244141
38GRK61.30206272
39EPHA21.25949720
40ERBB21.24648099
41EEF2K1.22991049
42CAMK1D1.22805983
43PAK31.21785267
44KIT1.20641983
45PDGFRB1.15309445
46ERN11.15101050
47DMPK1.14943690
48FGFR31.12871385
49LRRK21.09832784
50NTRK11.09665356
51PAK21.08745223
52PTK21.07893397
53FLT31.07017827
54CDK61.06787938
55DAPK20.96419015
56DYRK1B0.91617150
57FGFR20.88969514
58ERBB30.85205584
59MAP3K100.84899202
60STK30.84588290
61MAP3K20.82833853
62TIE10.81425239
63PHKG10.81409369
64PHKG20.81409369
65MYLK0.81334895
66MAPKAPK30.80792154
67ABL20.77826111
68ROCK10.77130184
69MTOR0.76414631
70WNK10.75001912
71MAP3K70.74089344
72STK38L0.73942730
73MET0.73106166
74MAP3K60.72229524
75MAPK70.69627346
76ROCK20.68659059
77OBSCN0.68121364
78MARK10.68009786
79TRPM70.67325474
80DAPK30.66141581
81ILK0.64427346
82STK380.62957240
83PRKD30.61475058
84CAMK2G0.61236258
85ICK0.60798538
86OXSR10.58238898
87RPS6KA20.57933453
88PRKD10.56723475
89PRKG20.56646346
90MAP3K30.55856918
91MAP2K10.52459534
92SMG10.52380075
93PIM20.51515626
94MOS0.49892478
95TGFBR10.49396051
96TYRO30.49140599
97KSR20.48516525
98MAPK40.44585591
99MELK0.44407973
100SGK30.43537539
101PAK60.43178558
102PTK2B0.43123698
103ZAP700.41815162
104CDC42BPA0.41667961
105SRC0.41359464
106CSNK1A1L0.40644106
107MAP3K130.40199857
108KSR10.39868430
109GSK3A0.39278543
110CDK120.37268959
111NME20.37265395
112FRK0.36325064
113CDK80.34416768
114RPS6KA60.33646248
115HIPK20.33000037
116TAOK10.32697257
117PDPK10.32107578
118PIK3CG0.31195104
119ALK0.30989340
120CLK10.30423785
121RPS6KC10.29597173
122RPS6KL10.29597173
123ARAF0.29316754
124PRKCE0.29151250
125FYN0.28631864
126MAPKAPK20.28446654
127PRKCH0.28293584
128JAK10.28176413
129EGFR0.28112087
130PNCK0.27897222
131MARK20.27548667
132INSR0.26079989
133CSNK1G10.25945226
134IGF1R0.24939500
135RPS6KA10.24029993
136CDK140.23124883

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.10901010
2Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.58379112
3Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.57187077
4Focal adhesion_Homo sapiens_hsa045102.42756381
5Adherens junction_Homo sapiens_hsa045202.34287505
6Glycosaminoglycan degradation_Homo sapiens_hsa005312.32039220
7Dilated cardiomyopathy_Homo sapiens_hsa054142.26343574
8Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.18333144
9Basal cell carcinoma_Homo sapiens_hsa052172.06959618
10Hippo signaling pathway_Homo sapiens_hsa043901.93180547
11Proteoglycans in cancer_Homo sapiens_hsa052051.93099364
12Amoebiasis_Homo sapiens_hsa051461.83355309
13Protein digestion and absorption_Homo sapiens_hsa049741.77474245
14Bladder cancer_Homo sapiens_hsa052191.64793214
15Small cell lung cancer_Homo sapiens_hsa052221.61652022
16Endometrial cancer_Homo sapiens_hsa052131.54306499
17Tight junction_Homo sapiens_hsa045301.54293241
18AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.53213328
19Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.51263318
20Axon guidance_Homo sapiens_hsa043601.47538752
21Pancreatic cancer_Homo sapiens_hsa052121.46867886
22Hedgehog signaling pathway_Homo sapiens_hsa043401.46751112
23Notch signaling pathway_Homo sapiens_hsa043301.45370378
24Chronic myeloid leukemia_Homo sapiens_hsa052201.39673843
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.38235022
26Complement and coagulation cascades_Homo sapiens_hsa046101.33610550
27Melanogenesis_Homo sapiens_hsa049161.31443069
28Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.30391114
29Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.29374223
30Renal cell carcinoma_Homo sapiens_hsa052111.29252573
31TGF-beta signaling pathway_Homo sapiens_hsa043501.28458510
32Central carbon metabolism in cancer_Homo sapiens_hsa052301.24794659
33Wnt signaling pathway_Homo sapiens_hsa043101.22689976
34Other glycan degradation_Homo sapiens_hsa005111.22679287
35MicroRNAs in cancer_Homo sapiens_hsa052061.20938798
36Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.19925832
37Insulin resistance_Homo sapiens_hsa049311.18899679
38Viral myocarditis_Homo sapiens_hsa054161.16732406
39Glioma_Homo sapiens_hsa052141.15869529
40Dorso-ventral axis formation_Homo sapiens_hsa043201.15799057
41Prion diseases_Homo sapiens_hsa050201.13827109
42Malaria_Homo sapiens_hsa051441.12764289
43Colorectal cancer_Homo sapiens_hsa052101.12149338
44Prostate cancer_Homo sapiens_hsa052151.11747024
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.10922422
46Regulation of actin cytoskeleton_Homo sapiens_hsa048101.10795503
47Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.07056022
48Pathways in cancer_Homo sapiens_hsa052001.06854725
49Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.04701860
50Melanoma_Homo sapiens_hsa052181.04310998
51Estrogen signaling pathway_Homo sapiens_hsa049151.03220955
52Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.02522152
53PI3K-Akt signaling pathway_Homo sapiens_hsa041511.02412959
54Thyroid hormone signaling pathway_Homo sapiens_hsa049190.99397917
55Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.97193780
56Non-small cell lung cancer_Homo sapiens_hsa052230.94753097
57ErbB signaling pathway_Homo sapiens_hsa040120.94533004
58Gastric acid secretion_Homo sapiens_hsa049710.93432854
59Insulin signaling pathway_Homo sapiens_hsa049100.92991522
60Toxoplasmosis_Homo sapiens_hsa051450.92934028
61Rap1 signaling pathway_Homo sapiens_hsa040150.92530138
62mTOR signaling pathway_Homo sapiens_hsa041500.91983887
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.91398231
64Fatty acid biosynthesis_Homo sapiens_hsa000610.90933600
65Vibrio cholerae infection_Homo sapiens_hsa051100.88245005
66Salivary secretion_Homo sapiens_hsa049700.86370877
67Gap junction_Homo sapiens_hsa045400.84188052
68Collecting duct acid secretion_Homo sapiens_hsa049660.84174940
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83348203
70AMPK signaling pathway_Homo sapiens_hsa041520.80757319
71Prolactin signaling pathway_Homo sapiens_hsa049170.79452498
72Lysine degradation_Homo sapiens_hsa003100.78886421
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.78672456
74Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77515072
75HIF-1 signaling pathway_Homo sapiens_hsa040660.76736813
76Oxytocin signaling pathway_Homo sapiens_hsa049210.76456456
77Renin secretion_Homo sapiens_hsa049240.76046194
78Lysosome_Homo sapiens_hsa041420.75292415
79Calcium signaling pathway_Homo sapiens_hsa040200.74452350
80Cocaine addiction_Homo sapiens_hsa050300.71478566
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.70995473
82VEGF signaling pathway_Homo sapiens_hsa043700.70892160
83Platelet activation_Homo sapiens_hsa046110.70220436
84Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68245991
85GnRH signaling pathway_Homo sapiens_hsa049120.67124470
86Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.66070010
87FoxO signaling pathway_Homo sapiens_hsa040680.64827882
88Aldosterone synthesis and secretion_Homo sapiens_hsa049250.64373215
89Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63866028
90Thyroid hormone synthesis_Homo sapiens_hsa049180.63532956
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.63472468
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.62505194
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59882946
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.59645993
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58780960
96Glucagon signaling pathway_Homo sapiens_hsa049220.58069995
97Thyroid cancer_Homo sapiens_hsa052160.57560678
98Type II diabetes mellitus_Homo sapiens_hsa049300.57066881
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.56854395
100HTLV-I infection_Homo sapiens_hsa051660.56099448
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55700184
102MAPK signaling pathway_Homo sapiens_hsa040100.54951860
103Acute myeloid leukemia_Homo sapiens_hsa052210.53890430
104Cholinergic synapse_Homo sapiens_hsa047250.50031260
105Endocytosis_Homo sapiens_hsa041440.49655632
106Renin-angiotensin system_Homo sapiens_hsa046140.49281963
107N-Glycan biosynthesis_Homo sapiens_hsa005100.48204706
108Ras signaling pathway_Homo sapiens_hsa040140.47920684
109Insulin secretion_Homo sapiens_hsa049110.47403997
110cAMP signaling pathway_Homo sapiens_hsa040240.47143420
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.46211571
112Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.45353711
113TNF signaling pathway_Homo sapiens_hsa046680.45244226
114Choline metabolism in cancer_Homo sapiens_hsa052310.45048213
115Fatty acid metabolism_Homo sapiens_hsa012120.44968213
116Circadian entrainment_Homo sapiens_hsa047130.44810531
117Sulfur metabolism_Homo sapiens_hsa009200.43965554
118Pertussis_Homo sapiens_hsa051330.43703245
119Long-term potentiation_Homo sapiens_hsa047200.43284314

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