HPDL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1purine nucleobase biosynthetic process (GO:0009113)6.32658551
2ribosome assembly (GO:0042255)5.98206155
3nucleobase biosynthetic process (GO:0046112)5.90011397
4folic acid metabolic process (GO:0046655)5.30158395
5DNA unwinding involved in DNA replication (GO:0006268)4.94919082
6proteasome assembly (GO:0043248)4.93586628
7mitotic metaphase plate congression (GO:0007080)4.91413956
8ribosome biogenesis (GO:0042254)4.90463023
9formation of translation preinitiation complex (GO:0001731)4.62957296
10rRNA modification (GO:0000154)4.53832732
11DNA deamination (GO:0045006)4.51448224
12folic acid transport (GO:0015884)4.50992382
13telomere maintenance via semi-conservative replication (GO:0032201)4.45525454
14DNA replication checkpoint (GO:0000076)4.35491751
15maturation of SSU-rRNA (GO:0030490)4.31099137
16transcription elongation from RNA polymerase III promoter (GO:0006385)4.24959744
17termination of RNA polymerase III transcription (GO:0006386)4.24959744
18anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.20978504
19pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.15678933
20positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.14578187
21ribosomal small subunit biogenesis (GO:0042274)4.14394667
22regulation of spindle organization (GO:0090224)4.10208000
23regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.08664248
24negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.04229678
25ribonucleoprotein complex biogenesis (GO:0022613)4.04179035
26termination of RNA polymerase I transcription (GO:0006363)3.96230466
27transcription elongation from RNA polymerase I promoter (GO:0006362)3.93939910
28intestinal epithelial cell development (GO:0060576)3.91964988
29transcription from RNA polymerase I promoter (GO:0006360)3.86045984
30regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.85702653
31transcription from mitochondrial promoter (GO:0006390)3.84928734
32rRNA processing (GO:0006364)3.79208765
33positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.77771635
34regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.77270639
35ribosomal large subunit biogenesis (GO:0042273)3.75128484
367-methylguanosine mRNA capping (GO:0006370)3.73606327
37establishment of integrated proviral latency (GO:0075713)3.73421163
38metaphase plate congression (GO:0051310)3.71821663
39spliceosomal snRNP assembly (GO:0000387)3.71731785
40regulation of translation in response to stress (GO:0043555)3.71723563
41telomere maintenance via recombination (GO:0000722)3.70023569
42blastocyst development (GO:0001824)3.69389437
43rRNA metabolic process (GO:0016072)3.67656933
44amino acid salvage (GO:0043102)3.66122306
45L-methionine salvage (GO:0071267)3.66122306
46L-methionine biosynthetic process (GO:0071265)3.66122306
47establishment of protein localization to mitochondrial membrane (GO:0090151)3.65744408
48viral mRNA export from host cell nucleus (GO:0046784)3.65085665
49negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.64043997
50negative regulation of ligase activity (GO:0051352)3.64043997
51DNA strand renaturation (GO:0000733)3.63039080
52RNA capping (GO:0036260)3.60455959
537-methylguanosine RNA capping (GO:0009452)3.60455959
54negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.58537221
55mitochondrial RNA metabolic process (GO:0000959)3.56875846
56DNA replication initiation (GO:0006270)3.56793357
57mitotic chromosome condensation (GO:0007076)3.54411816
58positive regulation of ligase activity (GO:0051351)3.54304086
59lung-associated mesenchyme development (GO:0060484)3.53503416
60mitotic recombination (GO:0006312)3.53428266
61vitamin transmembrane transport (GO:0035461)3.50526616
62base-excision repair, AP site formation (GO:0006285)3.50327466
63regulation of mitochondrial translation (GO:0070129)3.49000519
64transcription initiation from RNA polymerase I promoter (GO:0006361)3.47494693
65regulation of cellular amino acid metabolic process (GO:0006521)3.42858649
66ribosomal small subunit assembly (GO:0000028)3.41645572
67pseudouridine synthesis (GO:0001522)3.41464370
68protein localization to kinetochore (GO:0034501)3.39918550
69mitotic sister chromatid segregation (GO:0000070)3.38890310
70positive regulation of chromosome segregation (GO:0051984)3.37586764
71maturation of 5.8S rRNA (GO:0000460)3.36958871
72mitotic nuclear envelope disassembly (GO:0007077)3.36256339
73rRNA methylation (GO:0031167)3.34748614
74regulation of ubiquitin-protein transferase activity (GO:0051438)3.32882325
75pyrimidine nucleotide catabolic process (GO:0006244)3.32637552
76CENP-A containing nucleosome assembly (GO:0034080)3.31728176
77protein localization to chromosome, centromeric region (GO:0071459)3.31677052
78chromatin remodeling at centromere (GO:0031055)3.31550178
79nuclear pore complex assembly (GO:0051292)3.28509439
80DNA duplex unwinding (GO:0032508)3.28431791
81interferon-gamma secretion (GO:0072643)3.26721047
82spindle checkpoint (GO:0031577)3.26228049
83base-excision repair (GO:0006284)3.25921953
84rRNA transcription (GO:0009303)3.24790530
85pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.24448219
86regulation of translational termination (GO:0006449)3.23474547
87DNA strand elongation involved in DNA replication (GO:0006271)3.23447802
88regulation of mitotic spindle organization (GO:0060236)3.21341942
89negative regulation of chromosome segregation (GO:0051985)3.20929223
90negative regulation of mRNA processing (GO:0050686)3.20824821
91L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.19605561
92mitotic spindle checkpoint (GO:0071174)3.18859731
93DNA geometric change (GO:0032392)3.18408116
94signal transduction involved in DNA damage checkpoint (GO:0072422)3.17805526
95signal transduction involved in DNA integrity checkpoint (GO:0072401)3.17805526
96glycine metabolic process (GO:0006544)3.17442984
97methionine biosynthetic process (GO:0009086)3.17370895
98meiotic chromosome segregation (GO:0045132)3.15933183
99negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.15838725
100negative regulation of sister chromatid segregation (GO:0033046)3.15838725
101negative regulation of mitotic sister chromatid separation (GO:2000816)3.15838725
102negative regulation of mitotic sister chromatid segregation (GO:0033048)3.15838725
103cell cycle G1/S phase transition (GO:0044843)3.15609030
104G1/S transition of mitotic cell cycle (GO:0000082)3.15609030
105regulation of ligase activity (GO:0051340)3.15074468
106signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.14741716
107signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.14741716
108signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.14741716
109mitotic spindle assembly checkpoint (GO:0007094)3.14615825
110oxidative phosphorylation (GO:0006119)3.13854024
111tRNA methylation (GO:0030488)3.13627200
112DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.12328176
113signal transduction involved in cell cycle checkpoint (GO:0072395)3.11878110
114negative regulation of translational initiation (GO:0045947)3.10641350
115deoxyribonucleotide catabolic process (GO:0009264)3.10234060
116nuclear envelope disassembly (GO:0051081)3.10079445
117membrane disassembly (GO:0030397)3.10079445
118cellular component biogenesis (GO:0044085)3.08908766
119ncRNA 3-end processing (GO:0043628)3.08821901
120GMP metabolic process (GO:0046037)3.08470313
121regulation of translational fidelity (GO:0006450)3.07792550
122telomere maintenance via telomere lengthening (GO:0010833)3.07463056
123intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.07190285
124signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.07190285
125deoxyribose phosphate catabolic process (GO:0046386)3.06968355
126DNA strand elongation (GO:0022616)3.06581081
127spindle assembly checkpoint (GO:0071173)3.06515539
128negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.05747935
129regulation of chromosome segregation (GO:0051983)3.05717623
130chaperone-mediated protein transport (GO:0072321)3.04819418
131ncRNA processing (GO:0034470)3.03327047
132establishment of chromosome localization (GO:0051303)3.02976034
133IMP biosynthetic process (GO:0006188)3.02555719
134negative regulation of mRNA metabolic process (GO:1903312)3.01494255
135DNA-templated transcription, elongation (GO:0006354)3.01427046
136negative regulation of RNA splicing (GO:0033119)3.01092607
137protein targeting to mitochondrion (GO:0006626)2.99441740
138sister chromatid segregation (GO:0000819)2.99102911
139deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.98960261
140establishment of viral latency (GO:0019043)2.98763929
141termination of RNA polymerase II transcription (GO:0006369)2.98499368
142NADH metabolic process (GO:0006734)2.97970206
143methionine metabolic process (GO:0006555)2.97956231
144DNA replication-dependent nucleosome assembly (GO:0006335)2.97806732
145L-serine metabolic process (GO:0006563)2.97456307
146DNA replication-dependent nucleosome organization (GO:0034723)2.96054469
147negative regulation of B cell apoptotic process (GO:0002903)2.94734723
148viral transcription (GO:0019083)2.94725077
149peptidyl-arginine omega-N-methylation (GO:0035247)2.93586766
150GDP-mannose metabolic process (GO:0019673)2.90836814
151nucleotide-excision repair, DNA gap filling (GO:0006297)2.90738183
152translational termination (GO:0006415)2.90410609
153DNA catabolic process, exonucleolytic (GO:0000738)2.90264471
154kinetochore organization (GO:0051383)2.87406999
155tRNA modification (GO:0006400)2.87392192
156histone arginine methylation (GO:0034969)2.85450215
157nuclear pore organization (GO:0006999)2.83956342
158ncRNA metabolic process (GO:0034660)2.83051108
159chromatin assembly or disassembly (GO:0006333)2.82267518

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.22893324
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.30457913
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.26821182
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.62526969
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.59259824
6ETS1_20019798_ChIP-Seq_JURKAT_Human3.57081367
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.40035835
8CREB1_15753290_ChIP-ChIP_HEK293T_Human3.33518123
9MYC_19079543_ChIP-ChIP_MESCs_Mouse3.29413538
10FOXM1_23109430_ChIP-Seq_U2OS_Human3.23908053
11GABP_17652178_ChIP-ChIP_JURKAT_Human3.19524631
12EST1_17652178_ChIP-ChIP_JURKAT_Human3.12249162
13MYC_18358816_ChIP-ChIP_MESCs_Mouse3.04903409
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91048888
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.70346736
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.63675874
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.62794161
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.50769882
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.46077535
20VDR_23849224_ChIP-Seq_CD4+_Human2.32385250
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.27981438
22NANOG_18555785_ChIP-Seq_MESCs_Mouse2.27437258
23XRN2_22483619_ChIP-Seq_HELA_Human2.26627814
24* MYC_22102868_ChIP-Seq_BL_Human2.22004114
25AR_21909140_ChIP-Seq_LNCAP_Human2.21714032
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17852157
27VDR_21846776_ChIP-Seq_THP-1_Human2.12869898
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.10113052
29POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.07412317
30YY1_21170310_ChIP-Seq_MESCs_Mouse2.04475937
31GABP_19822575_ChIP-Seq_HepG2_Human2.03343216
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.03149987
33POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.99654468
34ZNF263_19887448_ChIP-Seq_K562_Human1.98336197
35DCP1A_22483619_ChIP-Seq_HELA_Human1.98331105
36HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.96232230
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.93335449
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91118269
39FOXP3_21729870_ChIP-Seq_TREG_Human1.81263149
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.69959423
41TTF2_22483619_ChIP-Seq_HELA_Human1.69085317
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64621781
43SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.62254025
44STAT3_1855785_ChIP-Seq_MESCs_Mouse1.61924794
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60470908
46KDM5A_27292631_Chip-Seq_BREAST_Human1.59198469
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54926454
48KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51351672
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49280928
50KLF4_18555785_ChIP-Seq_MESCs_Mouse1.46736800
51E2F1_21310950_ChIP-Seq_MCF-7_Human1.43076636
52NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.42414707
53KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.41637252
54TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.41145282
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.39024922
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38641454
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.34705357
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33262971
59CIITA_25753668_ChIP-Seq_RAJI_Human1.32634086
60NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.30921167
61CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26332226
62PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.26096922
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25110722
64NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.25024139
65ELK1_22589737_ChIP-Seq_MCF10A_Human1.22233619
66DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21722419
67CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20556099
68ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19770420
69FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18983521
70CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.17600047
71KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.17331833
72KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.17331833
73KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.17331833
74DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.17005601
75ELK1_19687146_ChIP-ChIP_HELA_Human1.15338677
76TCF3_18692474_ChIP-Seq_MEFs_Mouse1.15175166
77NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.14299112
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.13897877
79KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.13498237
80BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11829541
81FOXP1_21924763_ChIP-Seq_HESCs_Human1.11010522
82OCT4_18692474_ChIP-Seq_MEFs_Mouse1.10507850
83* TET1_21451524_ChIP-Seq_MESCs_Mouse1.09728160
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.09693879
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.08963830
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.08006700
87* P68_20966046_ChIP-Seq_HELA_Human1.07680452
88PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.07005060
89ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.06774168
90SOX2_18692474_ChIP-Seq_MEFs_Mouse1.05871224
91MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05819245
92NANOG_21062744_ChIP-ChIP_HESCs_Human1.05341525
93CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02548539
94SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.02256646
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00512038
96PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99278236
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99221909
98CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98353359
99CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97981127
100LXR_22292898_ChIP-Seq_THP-1_Human0.97813103
101HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97604728
102MAF_26560356_Chip-Seq_TH2_Human0.97457343
103SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.96661777
104POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.96162309
105SOX2_18555785_ChIP-Seq_MESCs_Mouse0.96045302
106NANOG_18692474_ChIP-Seq_MEFs_Mouse0.94648242
107SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.94448711
108TFEB_21752829_ChIP-Seq_HELA_Human0.93834455
109CTCF_18555785_ChIP-Seq_MESCs_Mouse0.92798704
110EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.92691029
111HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92066026
112SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.91067977
113* RACK7_27058665_Chip-Seq_MCF-7_Human0.90925411
114TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90674944
115* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.90602011
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.89890146
117* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.89798143
118CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89759729
119SRY_22984422_ChIP-ChIP_TESTIS_Rat0.88534742
120TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.85626002
121NOTCH1_21737748_ChIP-Seq_TLL_Human0.85233317
122SALL1_21062744_ChIP-ChIP_HESCs_Human0.84859073
123* ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.84766262
124* CTCF_21964334_Chip-Seq_Bcells_Human0.84629575
125TP63_19390658_ChIP-ChIP_HaCaT_Human0.84079135
126TCF3_18692474_ChIP-Seq_MESCs_Mouse0.82914745

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching7.01789945
2MP0003111_abnormal_nucleus_morphology5.29841685
3MP0004957_abnormal_blastocyst_morpholog4.87576183
4MP0003077_abnormal_cell_cycle3.76412132
5MP0003718_maternal_effect3.75449911
6MP0010094_abnormal_chromosome_stability3.74233306
7MP0009840_abnormal_foam_cell3.04208300
8MP0008260_abnormal_autophagy3.03718097
9MP0008058_abnormal_DNA_repair2.88247918
10MP0008932_abnormal_embryonic_tissue2.75276858
11MP0008057_abnormal_DNA_replication2.71488731
12MP0003123_paternal_imprinting2.63463926
13MP0001730_embryonic_growth_arrest2.63289489
14MP0003786_premature_aging2.44187266
15MP0005083_abnormal_biliary_tract2.05911453
16MP0005380_embryogenesis_phenotype2.02114241
17MP0001672_abnormal_embryogenesis/_devel2.02114241
18MP0000350_abnormal_cell_proliferation1.98191196
19MP0003315_abnormal_perineum_morphology1.93431008
20MP0005377_hearing/vestibular/ear_phenot1.88116553
21MP0003878_abnormal_ear_physiology1.88116553
22MP0008007_abnormal_cellular_replicative1.82164313
23MP0008877_abnormal_DNA_methylation1.79033442
24MP0010352_gastrointestinal_tract_polyps1.74228817
25MP0003984_embryonic_growth_retardation1.74175635
26MP0002088_abnormal_embryonic_growth/wei1.71778680
27MP0001697_abnormal_embryo_size1.69394254
28MP0002080_prenatal_lethality1.68865068
29MP0003646_muscle_fatigue1.62848870
30MP0001661_extended_life_span1.60026415
31MP0005451_abnormal_body_composition1.51299428
32MP0006035_abnormal_mitochondrial_morpho1.49110235
33MP0000750_abnormal_muscle_regeneration1.44402201
34MP0005395_other_phenotype1.43899745
35MP0010307_abnormal_tumor_latency1.43880542
36MP0002085_abnormal_embryonic_tissue1.43103199
37MP0003567_abnormal_fetal_cardiomyocyte1.42908114
38MP0003806_abnormal_nucleotide_metabolis1.41662656
39MP0003221_abnormal_cardiomyocyte_apopto1.41197053
40MP0005423_abnormal_somatic_nervous1.37405417
41MP0002086_abnormal_extraembryonic_tissu1.33456150
42MP0001542_abnormal_bone_strength1.30838628
43MP0003941_abnormal_skin_development1.29346155
44MP0000358_abnormal_cell_content/1.27466953
45MP0005076_abnormal_cell_differentiation1.25607561
46MP0001727_abnormal_embryo_implantation1.25271135
47MP0004019_abnormal_vitamin_homeostasis1.25241216
48MP0009333_abnormal_splenocyte_physiolog1.24647193
49MP0002084_abnormal_developmental_patter1.22802096
50MP0005171_absent_coat_pigmentation1.21826350
51MP0002210_abnormal_sex_determination1.20624272
52MP0001986_abnormal_taste_sensitivity1.18453912
53MP0001145_abnormal_male_reproductive1.16278026
54MP0002396_abnormal_hematopoietic_system1.15966344
55MP0005670_abnormal_white_adipose1.15875122
56MP0004808_abnormal_hematopoietic_stem1.15776879
57MP0006036_abnormal_mitochondrial_physio1.14510898
58MP0002653_abnormal_ependyma_morphology1.14328560
59MP0000313_abnormal_cell_death1.12934724
60MP0003938_abnormal_ear_development1.08433287
61MP0004233_abnormal_muscle_weight1.07480925
62MP0000490_abnormal_crypts_of1.05850290
63MP0009278_abnormal_bone_marrow1.05736074
64MP0001929_abnormal_gametogenesis1.04642830
65MP0003119_abnormal_digestive_system1.04225748
66MP0005220_abnormal_exocrine_pancreas1.02889662
67MP0005174_abnormal_tail_pigmentation1.02875674
68MP0004084_abnormal_cardiac_muscle1.01624773
69MP0009697_abnormal_copulation0.98253592
70MP0004185_abnormal_adipocyte_glucose0.97325107
71MP0009379_abnormal_foot_pigmentation0.97195722
72MP0005389_reproductive_system_phenotype0.96916456
73MP0009672_abnormal_birth_weight0.96897431
74MP0000703_abnormal_thymus_morphology0.96150738
75MP0003763_abnormal_thymus_physiology0.94555041
76MP0004197_abnormal_fetal_growth/weight/0.94507660
77MP0001756_abnormal_urination0.93993822
78MP0000653_abnormal_sex_gland0.93183593
79MP0002019_abnormal_tumor_incidence0.92218465
80MP0002160_abnormal_reproductive_system0.91473095
81MP0000747_muscle_weakness0.90758714
82MP0003136_yellow_coat_color0.90414261
83MP0000537_abnormal_urethra_morphology0.89917718
84MP0003186_abnormal_redox_activity0.88175281
85MP0010030_abnormal_orbit_morphology0.87399170
86MP0005384_cellular_phenotype0.86125138
87MP0010234_abnormal_vibrissa_follicle0.84464065
88MP0005332_abnormal_amino_acid0.84241000
89MP0002269_muscular_atrophy0.84036773
90MP0001293_anophthalmia0.83908413
91MP0005621_abnormal_cell_physiology0.83231786
92MP0001919_abnormal_reproductive_system0.82931480
93MP0008789_abnormal_olfactory_epithelium0.82862541
94MP0002254_reproductive_system_inflammat0.81955013
95MP0000015_abnormal_ear_pigmentation0.81107467
96MP0005075_abnormal_melanosome_morpholog0.80272998
97MP0002398_abnormal_bone_marrow0.79861644
98MP0004147_increased_porphyrin_level0.79618174
99MP0000627_abnormal_mammary_gland0.79539418
100MP0002722_abnormal_immune_system0.78492162
101MP0002877_abnormal_melanocyte_morpholog0.76405986
102MP0005330_cardiomyopathy0.74322044
103MP0009931_abnormal_skin_appearance0.73988384
104MP0004133_heterotaxia0.71957338
105MP0000477_abnormal_intestine_morphology0.70716457
106MP0003937_abnormal_limbs/digits/tail_de0.69979504
107MP0001188_hyperpigmentation0.69346442
108MP0001849_ear_inflammation0.69344342
109MP0002429_abnormal_blood_cell0.68481900
110MP0003787_abnormal_imprinting0.67544463
111MP0002796_impaired_skin_barrier0.67055834
112MP0003699_abnormal_female_reproductive0.66411972
113MP0001881_abnormal_mammary_gland0.66279762
114MP0002111_abnormal_tail_morphology0.66252155
115MP0005394_taste/olfaction_phenotype0.65898798
116MP0005499_abnormal_olfactory_system0.65898798
117MP0000428_abnormal_craniofacial_morphol0.65882632
118MP0005645_abnormal_hypothalamus_physiol0.65447146
119MP0000647_abnormal_sebaceous_gland0.64815718
120MP0000372_irregular_coat_pigmentation0.64705492
121MP0000689_abnormal_spleen_morphology0.64586917
122MP0009703_decreased_birth_body0.62902263
123MP0001764_abnormal_homeostasis0.62887739
124MP0002161_abnormal_fertility/fecundity0.62539402
125MP0003936_abnormal_reproductive_system0.60798883
126MP0005666_abnormal_adipose_tissue0.59014734
127MP0003698_abnormal_male_reproductive0.58769270
128MP0006292_abnormal_olfactory_placode0.57719881
129MP0002132_abnormal_respiratory_system0.57525679
130MP0005501_abnormal_skin_physiology0.54029105
131MP0004264_abnormal_extraembryonic_tissu0.53262250
132MP0002092_abnormal_eye_morphology0.52509336
133MP0002127_abnormal_cardiovascular_syste0.52168719
134MP0000383_abnormal_hair_follicle0.51402960
135MP0005397_hematopoietic_system_phenotyp0.51331087
136MP0001545_abnormal_hematopoietic_system0.51331087
137MP0001119_abnormal_female_reproductive0.50549939
138MP0003879_abnormal_hair_cell0.49792149

Predicted human phenotypes

RankGene SetZ-score
1Breast hypoplasia (HP:0003187)5.86424716
2Birth length less than 3rd percentile (HP:0003561)5.36441210
3Cerebral hypomyelination (HP:0006808)4.95993050
4Rough bone trabeculation (HP:0100670)4.46108906
5Hyperglycinemia (HP:0002154)4.39114923
6Carpal bone hypoplasia (HP:0001498)4.33158799
7Hyperglycinuria (HP:0003108)3.94862024
8Impulsivity (HP:0100710)3.88647546
9Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.85295283
10Ureteral duplication (HP:0000073)3.83959686
11Increased hepatocellular lipid droplets (HP:0006565)3.63958970
12Ragged-red muscle fibers (HP:0003200)3.58803336
13Multiple enchondromatosis (HP:0005701)3.58110336
14Lipid accumulation in hepatocytes (HP:0006561)3.53619012
15Increased intramyocellular lipid droplets (HP:0012240)3.53600885
16Progressive muscle weakness (HP:0003323)3.46324982
17Premature ovarian failure (HP:0008209)3.43232826
18Abnormality of the umbilical cord (HP:0010881)3.39514262
19Aplasia/Hypoplasia of the patella (HP:0006498)3.35963358
20Patellar aplasia (HP:0006443)3.35300892
21Abnormal trabecular bone morphology (HP:0100671)3.26589313
22Abnormality of serine family amino acid metabolism (HP:0010894)3.25370858
23Abnormality of glycine metabolism (HP:0010895)3.25370858
24Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.17001573
25Increased muscle lipid content (HP:0009058)3.16131826
26Absent radius (HP:0003974)3.14943479
27Secondary amenorrhea (HP:0000869)3.13700439
28Poikiloderma (HP:0001029)3.09801315
29CNS hypomyelination (HP:0003429)3.08169529
30Oral leukoplakia (HP:0002745)3.05248115
31Progressive external ophthalmoplegia (HP:0000590)3.04684712
32Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.02249874
33Abnormality of alanine metabolism (HP:0010916)3.02249874
34Hyperalaninemia (HP:0003348)3.02249874
35Aplasia involving forearm bones (HP:0009822)2.94237603
36Absent forearm bone (HP:0003953)2.94237603
37Megaloblastic anemia (HP:0001889)2.92243394
38Abnormality of serum amino acid levels (HP:0003112)2.91606625
39Abnormality of the anterior horn cell (HP:0006802)2.86824333
40Degeneration of anterior horn cells (HP:0002398)2.86824333
41Squamous cell carcinoma (HP:0002860)2.85608284
42Type I transferrin isoform profile (HP:0003642)2.84550609
43Death in infancy (HP:0001522)2.80114857
44Abnormality of the labia minora (HP:0012880)2.79910328
45Renal Fanconi syndrome (HP:0001994)2.79733698
46Increased CSF lactate (HP:0002490)2.78677592
47Reduced antithrombin III activity (HP:0001976)2.76980198
48Trismus (HP:0000211)2.75403542
49Hepatocellular necrosis (HP:0001404)2.67960070
50Microretrognathia (HP:0000308)2.67356243
51Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.65540439
52Entropion (HP:0000621)2.61197997
53Abnormal mitochondria in muscle tissue (HP:0008316)2.58309358
54Aplasia/Hypoplasia of the sacrum (HP:0008517)2.57619241
55Respiratory difficulties (HP:0002880)2.55598897
56Gout (HP:0001997)2.54292255
57Aplasia/Hypoplasia involving the musculature (HP:0001460)2.53707509
58Mitochondrial inheritance (HP:0001427)2.53229687
59Personality changes (HP:0000751)2.49775844
60Sparse eyelashes (HP:0000653)2.46699918
61Bundle branch block (HP:0011710)2.45550114
62Delusions (HP:0000746)2.43597224
63Pelvic girdle muscle weakness (HP:0003749)2.42981486
64Muscle fiber splitting (HP:0003555)2.41510427
65Pallor (HP:0000980)2.40676437
66Prolonged neonatal jaundice (HP:0006579)2.39346262
67Patent foramen ovale (HP:0001655)2.37678522
68Areflexia of lower limbs (HP:0002522)2.36581524
69Postnatal microcephaly (HP:0005484)2.34361088
70Macrocytic anemia (HP:0001972)2.33618071
71Aplastic anemia (HP:0001915)2.32670311
72Shoulder girdle muscle weakness (HP:0003547)2.31673016
73Atrioventricular block (HP:0001678)2.31312393
74Difficulty climbing stairs (HP:0003551)2.30450002
75Exercise intolerance (HP:0003546)2.30421691
76CNS demyelination (HP:0007305)2.28959299
77Abnormal protein glycosylation (HP:0012346)2.27685020
78Abnormal glycosylation (HP:0012345)2.27685020
79Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.27685020
80Abnormal protein N-linked glycosylation (HP:0012347)2.27685020
81Horseshoe kidney (HP:0000085)2.26120704
82Cerebral edema (HP:0002181)2.25466337
83Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.25247977
84Decreased activity of mitochondrial respiratory chain (HP:0008972)2.25247977
85Pancytopenia (HP:0001876)2.22434310
86Testicular atrophy (HP:0000029)2.22242740
87Lactic acidosis (HP:0003128)2.21875441
88Neoplasm of the pancreas (HP:0002894)2.21081008
89Ventricular fibrillation (HP:0001663)2.20392923
90Abnormal spermatogenesis (HP:0008669)2.18928529
91Abnormality of the distal phalanges of the toes (HP:0010182)2.18706881
92Meckel diverticulum (HP:0002245)2.18162655
93Abnormality of the preputium (HP:0100587)2.16320195
94Acute encephalopathy (HP:0006846)2.15747321
95Hepatic necrosis (HP:0002605)2.15721591
96Dyschromatopsia (HP:0007641)2.15462198
97Breast aplasia (HP:0100783)2.15404556
98Aplasia/hypoplasia of the humerus (HP:0006507)2.14791610
99Abnormalities of placenta or umbilical cord (HP:0001194)2.13889329
100Selective tooth agenesis (HP:0001592)2.13077879
101Acute necrotizing encephalopathy (HP:0006965)2.13063540
102Hypoplasia of the capital femoral epiphysis (HP:0003090)2.12147990
103Congenital, generalized hypertrichosis (HP:0004540)2.11030987
104Hypoplasia of the pons (HP:0012110)2.10066229
105Spinal muscular atrophy (HP:0007269)2.09542593
106Short thumb (HP:0009778)2.09377042
107Unsteady gait (HP:0002317)2.09312832
108Aplasia/Hypoplasia of the breasts (HP:0010311)2.09307032
109Abnormality of cells of the erythroid lineage (HP:0012130)2.08675827
110Rib fusion (HP:0000902)2.08267932
111Chromosomal breakage induced by crosslinking agents (HP:0003221)2.06902376
112Tetraplegia (HP:0002445)2.06528482
113Vaginal fistula (HP:0004320)2.06502129
114Rectal fistula (HP:0100590)2.05411850
115Rectovaginal fistula (HP:0000143)2.05411850
116Myelodysplasia (HP:0002863)2.05356029
117Reticulocytopenia (HP:0001896)2.05198259
118Aplasia/Hypoplasia of the uvula (HP:0010293)2.05052324
119Atrophy/Degeneration involving motor neurons (HP:0007373)2.04294467
120Premature graying of hair (HP:0002216)2.04053439
121Absent hand (HP:0004050)2.03200154
122Abnormality of the ileum (HP:0001549)2.01951143
123Bone marrow hypocellularity (HP:0005528)2.01829851
124Dysautonomia (HP:0002459)2.01720504
125Facial cleft (HP:0002006)2.01267111
126Absent thumb (HP:0009777)2.01013146
127Nausea (HP:0002018)2.00811183
128Abnormality of the hip-girdle musculature (HP:0001445)1.97837353
129Abnormality of the musculature of the pelvis (HP:0001469)1.97837353
130Intestinal fistula (HP:0100819)1.97119942
131Ependymoma (HP:0002888)1.95704150
132Glossoptosis (HP:0000162)1.95104345
133Hypergonadotropic hypogonadism (HP:0000815)1.90643469
134Abnormal number of erythroid precursors (HP:0012131)1.90186665
135Cellular immunodeficiency (HP:0005374)1.89949937
136Microvesicular hepatic steatosis (HP:0001414)1.89635998
137Lethargy (HP:0001254)1.88644458
138Sparse lateral eyebrow (HP:0005338)1.87025506
139Hypoplasia of the radius (HP:0002984)1.86166782
140Abnormality of the pons (HP:0007361)1.85726267
141Colon cancer (HP:0003003)1.82358629
142Cleft eyelid (HP:0000625)1.82305067
143Irregular epiphyses (HP:0010582)1.81727838
144Chromsome breakage (HP:0040012)1.81393880
145Increased serum lactate (HP:0002151)1.81351294
146External ophthalmoplegia (HP:0000544)1.81135575
147Abnormality of glycolysis (HP:0004366)1.80684941
148Increased serum pyruvate (HP:0003542)1.78971650
149Muscle fibrillation (HP:0010546)1.78783647
150Abnormality of chromosome stability (HP:0003220)1.78766140
151Proximal placement of thumb (HP:0009623)1.78191084
152Abnormality of pyrimidine metabolism (HP:0004353)1.77752332
153Thrombocytosis (HP:0001894)1.74329602
154Acute lymphatic leukemia (HP:0006721)1.72849127
155Abnormality of small intestinal villus morphology (HP:0011472)1.72347864
156Villous atrophy (HP:0011473)1.72347864
157Impaired proprioception (HP:0010831)1.70791340

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB16.79238966
2WEE14.98502817
3VRK24.13072218
4EPHA24.10215758
5PBK3.67694431
6TSSK63.25051175
7EIF2AK13.06180134
8SMG13.05471054
9PLK42.98510431
10AKT32.89904618
11STK162.59199054
12NEK22.52908494
13PNCK2.51966135
14TTK2.49345258
15NME22.37408772
16NEK12.31373334
17SRPK12.22407877
18BRSK21.91774294
19PLK11.87122760
20EIF2AK31.81245142
21PDK31.75474735
22PDK41.75474735
23DYRK31.64963187
24ZAK1.63472384
25PLK31.61942201
26CDC71.58364697
27MAP3K101.56601751
28TAF11.49235485
29IRAK31.42743098
30ACVR1B1.40599873
31PDK21.35656850
32BRSK11.35422806
33NME11.34566682
34STK38L1.32029936
35AURKA1.29291778
36AURKB1.25812832
37EEF2K1.22846785
38TESK21.22277092
39CHEK21.19869635
40NUAK11.17053313
41CCNB11.15849051
42PINK11.15545071
43BCKDK1.14202208
44LATS21.13293467
45MKNK21.07905917
46BRAF1.07254200
47MAP3K81.06547088
48MUSK1.04693950
49RPS6KB21.01516041
50CDK70.99348361
51DAPK10.96703208
52ARAF0.95879805
53CDK40.95670790
54PRKCI0.94592179
55ALK0.94249477
56PIM20.94003597
57WNK40.87876824
58STK30.82788438
59CHEK10.82723649
60RPS6KA40.82300614
61MKNK10.79247178
62PAK10.78711006
63TLK10.75916438
64ATR0.74083052
65MAP2K20.70226359
66MST1R0.69302029
67CDK80.67268695
68PAK40.67060267
69VRK10.66519844
70PRPF4B0.65616461
71CDK20.61393823
72ERN10.61196972
73EIF2AK20.59979369
74SIK10.59977000
75MST40.57140596
76CSNK2A20.55988392
77CDK60.55557080
78FLT30.55173859
79CSNK1E0.54926124
80MAP4K10.53344918
81CSNK2A10.52933590
82STK240.50309533
83MAP3K110.48924013
84MAPK110.48623041
85OXSR10.48316178
86DAPK30.48117891
87DYRK20.47470149
88ICK0.46283765
89MELK0.44846992
90PASK0.44735862
91STK390.44371913
92CDK90.44136257
93CDK10.40480005
94MAPK150.40193111
95RPS6KA10.37292262
96ABL20.36944729
97PIM10.36038022
98STK100.34808615
99TAOK20.33996619
100ATM0.32986625
101MAPKAPK50.32173611
102AKT20.32112171
103MTOR0.32096411
104NEK60.31279970
105STK40.29879041
106CDK11A0.29723560
107KDR0.28844742
108BMX0.28596819
109MAP3K30.28118757
110MARK10.27046026
111PRKCG0.26272925
112MAP3K50.23274946
113RPS6KA50.22809876
114RAF10.20768820
115SCYL20.20479764
116STK380.20394919
117TAOK10.20265181
118LATS10.19718451
119CSNK1G30.17457569
120CSNK1A10.17252789
121PRKAA10.15966395
122CSNK1G10.15743691
123DDR20.13959421
124CAMK2G0.13867045
125PRKDC0.12867961
126IRAK20.11836784
127MAPK100.11580015
128GRK60.11002607
129MARK30.09985108
130CDK120.09475311
131MAPK90.09434075
132MAP3K90.08561699

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.71618177
2Proteasome_Homo sapiens_hsa030504.58380137
3RNA polymerase_Homo sapiens_hsa030204.54979087
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.48114931
5RNA transport_Homo sapiens_hsa030133.39869774
6DNA replication_Homo sapiens_hsa030303.13625740
7Ribosome_Homo sapiens_hsa030102.72872304
8Spliceosome_Homo sapiens_hsa030402.71793707
9Pyrimidine metabolism_Homo sapiens_hsa002402.69500699
10Mismatch repair_Homo sapiens_hsa034302.58999633
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.17878630
12Cell cycle_Homo sapiens_hsa041102.17478323
13Base excision repair_Homo sapiens_hsa034102.16975887
14Folate biosynthesis_Homo sapiens_hsa007902.16958087
15Regulation of autophagy_Homo sapiens_hsa041402.12173638
16Nucleotide excision repair_Homo sapiens_hsa034202.06395662
17Homologous recombination_Homo sapiens_hsa034402.05149145
18Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.85925669
19Basal transcription factors_Homo sapiens_hsa030221.78004478
20Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.74241261
21Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.70591971
22One carbon pool by folate_Homo sapiens_hsa006701.66107366
23Purine metabolism_Homo sapiens_hsa002301.62650489
24Pentose phosphate pathway_Homo sapiens_hsa000301.62201644
25Cysteine and methionine metabolism_Homo sapiens_hsa002701.52854909
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.51951094
27Fanconi anemia pathway_Homo sapiens_hsa034601.45228814
28p53 signaling pathway_Homo sapiens_hsa041151.39597694
29Glycerophospholipid metabolism_Homo sapiens_hsa005641.37028862
30Fructose and mannose metabolism_Homo sapiens_hsa000511.32189112
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.28068910
32Biosynthesis of amino acids_Homo sapiens_hsa012301.22449336
33mRNA surveillance pathway_Homo sapiens_hsa030151.22418930
34RNA degradation_Homo sapiens_hsa030181.20589348
35Epstein-Barr virus infection_Homo sapiens_hsa051691.20144763
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.16627315
37Oocyte meiosis_Homo sapiens_hsa041141.15551613
38Pyruvate metabolism_Homo sapiens_hsa006201.14947613
39Vitamin digestion and absorption_Homo sapiens_hsa049771.14885009
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10196323
41Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.08587722
42Carbon metabolism_Homo sapiens_hsa012001.00846842
43N-Glycan biosynthesis_Homo sapiens_hsa005100.98226092
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96339035
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.96220713
46Sulfur relay system_Homo sapiens_hsa041220.91242390
47Fatty acid elongation_Homo sapiens_hsa000620.91117715
48Glutathione metabolism_Homo sapiens_hsa004800.82762255
49Cyanoamino acid metabolism_Homo sapiens_hsa004600.81258837
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78553678
51Alzheimers disease_Homo sapiens_hsa050100.76601290
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.75087299
53Huntingtons disease_Homo sapiens_hsa050160.74199677
54Primary immunodeficiency_Homo sapiens_hsa053400.73454264
55Non-homologous end-joining_Homo sapiens_hsa034500.71111874
56Selenocompound metabolism_Homo sapiens_hsa004500.69106518
57Alcoholism_Homo sapiens_hsa050340.61939430
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.60896993
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.58547768
60Metabolic pathways_Homo sapiens_hsa011000.58328709
61Arginine and proline metabolism_Homo sapiens_hsa003300.56826299
62Lysine degradation_Homo sapiens_hsa003100.53799949
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51043559
64Oxidative phosphorylation_Homo sapiens_hsa001900.49455954
65Renin-angiotensin system_Homo sapiens_hsa046140.48191765
66Parkinsons disease_Homo sapiens_hsa050120.48007451
67Galactose metabolism_Homo sapiens_hsa000520.47694264
68Bladder cancer_Homo sapiens_hsa052190.45512451
69Arginine biosynthesis_Homo sapiens_hsa002200.45391372
70Glycerolipid metabolism_Homo sapiens_hsa005610.43390916
71Arachidonic acid metabolism_Homo sapiens_hsa005900.40665444
72Fat digestion and absorption_Homo sapiens_hsa049750.37761024
73Protein export_Homo sapiens_hsa030600.36047565
74Antigen processing and presentation_Homo sapiens_hsa046120.36022290
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35925003
76mTOR signaling pathway_Homo sapiens_hsa041500.35665831
77Linoleic acid metabolism_Homo sapiens_hsa005910.35045115
78Steroid biosynthesis_Homo sapiens_hsa001000.33814087
79Viral carcinogenesis_Homo sapiens_hsa052030.32639399
80Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.31855770
81Circadian rhythm_Homo sapiens_hsa047100.31153094
82Hippo signaling pathway_Homo sapiens_hsa043900.28689468
83beta-Alanine metabolism_Homo sapiens_hsa004100.27352382
84Apoptosis_Homo sapiens_hsa042100.26159386
85Phenylalanine metabolism_Homo sapiens_hsa003600.26008526
86Tight junction_Homo sapiens_hsa045300.24446859
87alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24005077
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.23311570
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.21091974
90Longevity regulating pathway - mammal_Homo sapiens_hsa042110.20388167
91Hedgehog signaling pathway_Homo sapiens_hsa043400.19445840
92Fatty acid metabolism_Homo sapiens_hsa012120.18816660
93HTLV-I infection_Homo sapiens_hsa051660.18810740
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18336664
95Herpes simplex infection_Homo sapiens_hsa051680.18246789
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.17305163
97Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.16285766
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.16225919
99Peroxisome_Homo sapiens_hsa041460.16103417
100HIF-1 signaling pathway_Homo sapiens_hsa040660.15822793
101TGF-beta signaling pathway_Homo sapiens_hsa043500.14465506
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.14160316
103Acute myeloid leukemia_Homo sapiens_hsa052210.13510040
104Basal cell carcinoma_Homo sapiens_hsa052170.12808769
105Mineral absorption_Homo sapiens_hsa049780.12460388
106Shigellosis_Homo sapiens_hsa051310.11819688
107Tyrosine metabolism_Homo sapiens_hsa003500.11670530
108Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.11598797
109Lysosome_Homo sapiens_hsa041420.09794149
110Thyroid cancer_Homo sapiens_hsa052160.09757892
111Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.08911601
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.08811061
113Colorectal cancer_Homo sapiens_hsa052100.08765991
114Sphingolipid metabolism_Homo sapiens_hsa006000.08636495
115Propanoate metabolism_Homo sapiens_hsa006400.08486023
116Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.07902283
117AMPK signaling pathway_Homo sapiens_hsa041520.07509383
118Systemic lupus erythematosus_Homo sapiens_hsa053220.07149172
119FoxO signaling pathway_Homo sapiens_hsa040680.04638194
120Legionellosis_Homo sapiens_hsa051340.03792317
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.03761235
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.03565166
123Inositol phosphate metabolism_Homo sapiens_hsa005620.03202472
124Small cell lung cancer_Homo sapiens_hsa052220.02117170
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.02090599
126MicroRNAs in cancer_Homo sapiens_hsa052060.01247264
127Butanoate metabolism_Homo sapiens_hsa006500.01184978
128Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.00996762
129Cardiac muscle contraction_Homo sapiens_hsa04260-0.0140277

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »