HNRNPM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.83191197
2protein localization to kinetochore (GO:0034501)4.49636020
3DNA strand elongation involved in DNA replication (GO:0006271)4.44151597
4negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.34263890
5establishment of viral latency (GO:0019043)4.25959222
6DNA strand elongation (GO:0022616)4.19889558
7DNA replication initiation (GO:0006270)4.12643024
8protein complex localization (GO:0031503)4.05369720
9negative regulation of RNA splicing (GO:0033119)4.04979187
10nuclear pore organization (GO:0006999)4.01579189
11mitotic nuclear envelope disassembly (GO:0007077)3.92769854
12nuclear pore complex assembly (GO:0051292)3.86636068
13telomere maintenance via semi-conservative replication (GO:0032201)3.86441733
14formation of translation preinitiation complex (GO:0001731)3.85119782
15DNA duplex unwinding (GO:0032508)3.83002722
16DNA geometric change (GO:0032392)3.79667041
17protein localization to chromosome, centromeric region (GO:0071459)3.78156106
18folic acid-containing compound biosynthetic process (GO:0009396)3.71485689
19negative regulation of mRNA processing (GO:0050686)3.70070520
20DNA replication-dependent nucleosome assembly (GO:0006335)3.67462062
21DNA replication-dependent nucleosome organization (GO:0034723)3.67462062
22membrane disassembly (GO:0030397)3.64859303
23nuclear envelope disassembly (GO:0051081)3.64859303
24regulation of RNA export from nucleus (GO:0046831)3.63563516
25regulation of transcription from RNA polymerase I promoter (GO:0006356)3.61196843
26regulation of mRNA stability (GO:0043488)3.58498672
27histone arginine methylation (GO:0034969)3.55041907
28IMP biosynthetic process (GO:0006188)3.54712369
29mitotic chromosome condensation (GO:0007076)3.54627186
30ribosomal small subunit assembly (GO:0000028)3.52758258
31sister chromatid segregation (GO:0000819)3.51295603
32mitotic recombination (GO:0006312)3.50424972
33mitotic sister chromatid cohesion (GO:0007064)3.48946876
34dosage compensation (GO:0007549)3.45817324
35telomere maintenance via recombination (GO:0000722)3.45723917
36regulation of translational termination (GO:0006449)3.43735077
37ribosomal small subunit biogenesis (GO:0042274)3.43535030
38regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.42474343
39mitotic sister chromatid segregation (GO:0000070)3.41875705
40maturation of SSU-rRNA (GO:0030490)3.41653045
41cellular protein complex localization (GO:0034629)3.40929272
42nucleobase biosynthetic process (GO:0046112)3.39378695
43viral transcription (GO:0019083)3.37368814
44regulation of RNA stability (GO:0043487)3.35277415
45translesion synthesis (GO:0019985)3.32934926
46translational termination (GO:0006415)3.31456096
47mitotic metaphase plate congression (GO:0007080)3.31441886
48negative regulation of mRNA metabolic process (GO:1903312)3.30530232
49DNA replication checkpoint (GO:0000076)3.29609902
50* mRNA splicing, via spliceosome (GO:0000398)3.29505406
51* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.29505406
52heterochromatin organization (GO:0070828)3.29434892
53peptidyl-arginine N-methylation (GO:0035246)3.29411659
54peptidyl-arginine methylation (GO:0018216)3.29411659
55kinetochore organization (GO:0051383)3.26372828
56* RNA splicing, via transesterification reactions (GO:0000375)3.26362005
57DNA ligation (GO:0006266)3.18896815
58regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.18670598
59regulation of nucleobase-containing compound transport (GO:0032239)3.16614765
60pre-miRNA processing (GO:0031054)3.16388857
61DNA topological change (GO:0006265)3.16334008
62telomere maintenance via telomere lengthening (GO:0010833)3.15916486
63regulation of spindle organization (GO:0090224)3.15255390
64nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.12543053
65DNA replication-independent nucleosome organization (GO:0034724)3.12433187
66DNA replication-independent nucleosome assembly (GO:0006336)3.12433187
67translational elongation (GO:0006414)3.12015713
68regulation of translational fidelity (GO:0006450)3.11217082
69translational initiation (GO:0006413)3.11117924
70ribonucleoprotein complex biogenesis (GO:0022613)3.11062086
71DNA conformation change (GO:0071103)3.10130871
72viral mRNA export from host cell nucleus (GO:0046784)3.09997280
73IMP metabolic process (GO:0046040)3.08673875
74regulation of sister chromatid cohesion (GO:0007063)3.08539205
75regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.06936483
76proline biosynthetic process (GO:0006561)3.06929193
77negative regulation of histone methylation (GO:0031061)3.06872192
78chromatin assembly or disassembly (GO:0006333)3.05542990
79nucleotide-excision repair, DNA gap filling (GO:0006297)3.05285280
80pentose-phosphate shunt (GO:0006098)3.05067835
81ATP-dependent chromatin remodeling (GO:0043044)3.01233455
82metaphase plate congression (GO:0051310)3.00446414
83termination of RNA polymerase II transcription (GO:0006369)3.00242053
84ribosome assembly (GO:0042255)3.00064189
85chromosome condensation (GO:0030261)2.99785990
86mRNA stabilization (GO:0048255)2.99681440
87RNA stabilization (GO:0043489)2.99681440
883-UTR-mediated mRNA stabilization (GO:0070935)2.98257792
89postreplication repair (GO:0006301)2.98208680
90regulation of histone H3-K9 methylation (GO:0051570)2.97270935
91chromatin remodeling at centromere (GO:0031055)2.97079582
92positive regulation of chromosome segregation (GO:0051984)2.96401591
93CENP-A containing nucleosome assembly (GO:0034080)2.94765874
94mRNA export from nucleus (GO:0006406)2.93409265
95non-recombinational repair (GO:0000726)2.92659660
96double-strand break repair via nonhomologous end joining (GO:0006303)2.92659660
97nuclear envelope organization (GO:0006998)2.88536321
98pore complex assembly (GO:0046931)2.88134846
99spliceosomal tri-snRNP complex assembly (GO:0000244)2.87945060
100peptidyl-arginine omega-N-methylation (GO:0035247)2.85797740
101chromatin assembly (GO:0031497)2.85788411
102NADPH regeneration (GO:0006740)2.85651491
103regulation of chromosome segregation (GO:0051983)2.85542386
104L-serine metabolic process (GO:0006563)2.85446704
105protein export from nucleus (GO:0006611)2.84514479
106protein localization to chromosome (GO:0034502)2.83850746
107negative regulation of chromosome segregation (GO:0051985)2.82940878
108V(D)J recombination (GO:0033151)2.81752467
109regulation of mammary gland epithelial cell proliferation (GO:0033599)2.81718874
110establishment of chromosome localization (GO:0051303)2.81703106
111establishment of integrated proviral latency (GO:0075713)2.81398714
112cellular hyperosmotic response (GO:0071474)2.80096826
113purine nucleobase biosynthetic process (GO:0009113)2.79525159
114spindle assembly checkpoint (GO:0071173)2.79385331
115negative regulation of mitotic sister chromatid separation (GO:2000816)2.79259494
116negative regulation of mitotic sister chromatid segregation (GO:0033048)2.79259494
117negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.79259494
118negative regulation of sister chromatid segregation (GO:0033046)2.79259494
119rRNA transcription (GO:0009303)2.77792334
120nucleobase-containing small molecule interconversion (GO:0015949)2.77694570
121histone H2B ubiquitination (GO:0033523)2.77458802
122mitotic spindle assembly checkpoint (GO:0007094)2.77435166
123glucocorticoid receptor signaling pathway (GO:0042921)2.77189243
124ribosome biogenesis (GO:0042254)2.77010314
125spliceosomal snRNP assembly (GO:0000387)2.76817607
126protein-DNA complex disassembly (GO:0032986)2.76676073
127nucleosome disassembly (GO:0006337)2.76676073
128RNA export from nucleus (GO:0006405)2.74886076
129histone H2A acetylation (GO:0043968)2.74395639
130regulation of mitotic spindle organization (GO:0060236)2.73038051
131mRNA transport (GO:0051028)2.71552038
132base-excision repair (GO:0006284)2.71378490
133attachment of spindle microtubules to kinetochore (GO:0008608)2.71237313

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.29472283
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.92204623
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.90470652
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.75548150
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.69974471
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.20120658
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.19459972
8MYC_22102868_ChIP-Seq_BL_Human2.85486820
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.80430785
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.49360889
11XRN2_22483619_ChIP-Seq_HELA_Human2.31053892
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.30078737
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16487710
14AR_21909140_ChIP-Seq_LNCAP_Human2.15577196
15E2F1_21310950_ChIP-Seq_MCF-7_Human2.12039755
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.09781101
17CIITA_25753668_ChIP-Seq_RAJI_Human2.07738836
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.00983642
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.94175496
20* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.92818539
21CREB1_15753290_ChIP-ChIP_HEK293T_Human1.85747314
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.84437369
23VDR_21846776_ChIP-Seq_THP-1_Human1.80821847
24TP63_19390658_ChIP-ChIP_HaCaT_Human1.75863156
25NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.73338982
26ELF1_17652178_ChIP-ChIP_JURKAT_Human1.73135792
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.72712409
28KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.72565834
29VDR_23849224_ChIP-Seq_CD4+_Human1.72102366
30GABP_17652178_ChIP-ChIP_JURKAT_Human1.72000115
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69450105
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.67854150
33TTF2_22483619_ChIP-Seq_HELA_Human1.66626320
34FOXP3_21729870_ChIP-Seq_TREG_Human1.65795589
35JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.62053244
36ZFX_18555785_ChIP-Seq_MESCs_Mouse1.60517175
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.57267010
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.56860663
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.56576388
40CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.56352781
41* GABP_19822575_ChIP-Seq_HepG2_Human1.54127131
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.53344118
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.51064045
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50647901
45KDM5A_27292631_Chip-Seq_BREAST_Human1.49832098
46DCP1A_22483619_ChIP-Seq_HELA_Human1.49560663
47* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47093307
48TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.45350643
49CLOCK_20551151_ChIP-Seq_293T_Human1.42552504
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41229630
51THAP11_20581084_ChIP-Seq_MESCs_Mouse1.37855684
52ZNF263_19887448_ChIP-Seq_K562_Human1.37374996
53CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.30101247
54TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27444223
55NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.26298163
56DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25114342
57ELK1_19687146_ChIP-ChIP_HELA_Human1.22361800
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22121873
59KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19593427
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.19070813
61* TFEB_21752829_ChIP-Seq_HELA_Human1.17161227
62SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.17145918
63E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15782389
64TCF7_22412390_ChIP-Seq_EML_Mouse1.14232225
65UTX_26944678_Chip-Seq_JUKART_Human1.13786750
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.13662580
67ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.12474496
68ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11302608
69NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.11191774
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11001034
71STAT3_1855785_ChIP-Seq_MESCs_Mouse1.10729633
72SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.09657722
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.09450596
74POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09357738
75HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.08641632
76RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08629962
77MAF_26560356_Chip-Seq_TH1_Human1.08412915
78SOX2_18555785_ChIP-Seq_MESCs_Mouse1.07725170
79ZFP281_18757296_ChIP-ChIP_E14_Mouse1.07591854
80BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.07012537
81* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.02965150
82NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.02627883
83LXR_22292898_ChIP-Seq_THP-1_Human1.02464644
84* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01573172
85NANOG_21062744_ChIP-ChIP_HESCs_Human1.01045898
86KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.00130724
87KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.00130724
88KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.00130724
89NCOR1_26117541_ChIP-Seq_K562_Human0.99886080
90KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.99821091
91OCT4_18692474_ChIP-Seq_MEFs_Mouse0.99769214
92PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99604967
93PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.99273731
94ELK3_25401928_ChIP-Seq_HUVEC_Human0.99022839
95RACK7_27058665_Chip-Seq_MCF-7_Human0.98646312
96KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.98477932
97SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98447733
98FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.97248405
99CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95896439
100SPI1_23547873_ChIP-Seq_NB4_Human0.95660907
101YY1_21170310_ChIP-Seq_MESCs_Mouse0.95519998
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94939786
103GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94848092
104KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.93209486
105PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.93205834
106KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.92263502
107HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.89938359
108* CHD1_26751641_Chip-Seq_LNCaP_Human0.89895811
109ESR1_15608294_ChIP-ChIP_MCF-7_Human0.89065020
110MYB_26560356_Chip-Seq_TH2_Human0.88472690
111POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.88154942
112* KDM2B_26808549_Chip-Seq_DND41_Human0.87958195
113MYB_26560356_Chip-Seq_TH1_Human0.86684730
114DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.86003671
115SCL_19346495_ChIP-Seq_HPC-7_Human0.85028517
116NOTCH1_21737748_ChIP-Seq_TLL_Human0.84282237
117VDR_24763502_ChIP-Seq_THP-1_Human0.82716164
118TCF3_18692474_ChIP-Seq_MEFs_Mouse0.80865179
119TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.80743400

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.98319049
2MP0010094_abnormal_chromosome_stability3.78695087
3MP0003111_abnormal_nucleus_morphology3.72598644
4MP0004957_abnormal_blastocyst_morpholog3.54170517
5MP0003077_abnormal_cell_cycle3.40891608
6MP0008057_abnormal_DNA_replication3.05595216
7MP0002877_abnormal_melanocyte_morpholog2.94671905
8MP0010352_gastrointestinal_tract_polyps2.72862204
9MP0008007_abnormal_cellular_replicative2.66686522
10MP0001730_embryonic_growth_arrest2.37903693
11MP0002396_abnormal_hematopoietic_system2.36879032
12MP0003123_paternal_imprinting2.34957681
13MP0008058_abnormal_DNA_repair2.29851060
14MP0000350_abnormal_cell_proliferation2.23046642
15MP0010030_abnormal_orbit_morphology2.18860226
16MP0004185_abnormal_adipocyte_glucose2.09091087
17MP0005076_abnormal_cell_differentiation2.06250164
18MP0008932_abnormal_embryonic_tissue2.04503292
19MP0010307_abnormal_tumor_latency1.94233168
20MP0004808_abnormal_hematopoietic_stem1.93641115
21MP0000537_abnormal_urethra_morphology1.93006359
22MP0003705_abnormal_hypodermis_morpholog1.89751307
23MP0001672_abnormal_embryogenesis/_devel1.80731233
24MP0005380_embryogenesis_phenotype1.80731233
25MP0004197_abnormal_fetal_growth/weight/1.80612499
26MP0006054_spinal_hemorrhage1.79828601
27MP0001697_abnormal_embryo_size1.77896566
28MP0009053_abnormal_anal_canal1.74446890
29MP0003984_embryonic_growth_retardation1.72170915
30MP0002084_abnormal_developmental_patter1.69542217
31MP0002088_abnormal_embryonic_growth/wei1.69397913
32MP0002085_abnormal_embryonic_tissue1.67357769
33MP0000490_abnormal_crypts_of1.63261752
34MP0002080_prenatal_lethality1.62597549
35MP0003121_genomic_imprinting1.62123719
36MP0005451_abnormal_body_composition1.60961566
37MP0003567_abnormal_fetal_cardiomyocyte1.56006241
38MP0009278_abnormal_bone_marrow1.55974438
39MP0002086_abnormal_extraembryonic_tissu1.54455098
40MP0002796_impaired_skin_barrier1.51307547
41MP0005501_abnormal_skin_physiology1.44567237
42MP0000703_abnormal_thymus_morphology1.39387956
43MP0008877_abnormal_DNA_methylation1.37590731
44MP0000313_abnormal_cell_death1.33102059
45MP0003763_abnormal_thymus_physiology1.33014515
46MP0001293_anophthalmia1.30959258
47MP0002019_abnormal_tumor_incidence1.30635075
48MP0001545_abnormal_hematopoietic_system1.26677092
49MP0005397_hematopoietic_system_phenotyp1.26677092
50MP0002009_preneoplasia1.24714413
51MP0001849_ear_inflammation1.23677724
52MP0009333_abnormal_splenocyte_physiolog1.20845746
53MP0000733_abnormal_muscle_development1.20597031
54MP0002398_abnormal_bone_marrow1.19628025
55MP0000428_abnormal_craniofacial_morphol1.19498899
56MP0008260_abnormal_autophagy1.18406421
57MP0004858_abnormal_nervous_system1.15641305
58MP0009672_abnormal_birth_weight1.13128573
59MP0003890_abnormal_embryonic-extraembry1.12658665
60MP0000678_abnormal_parathyroid_gland1.12518928
61MP0002722_abnormal_immune_system1.08313420
62MP0001727_abnormal_embryo_implantation1.08291151
63MP0003941_abnormal_skin_development1.07728551
64MP0001915_intracranial_hemorrhage1.06997470
65MP0003119_abnormal_digestive_system1.05120470
66MP0003566_abnormal_cell_adhesion1.02205434
67MP0002653_abnormal_ependyma_morphology0.99130726
68MP0002092_abnormal_eye_morphology0.99064415
69MP0003786_premature_aging0.98939010
70MP0003115_abnormal_respiratory_system0.97501802
71MP0000689_abnormal_spleen_morphology0.97038991
72MP0005023_abnormal_wound_healing0.94540620
73MP0002089_abnormal_postnatal_growth/wei0.94413902
74MP0002111_abnormal_tail_morphology0.94143995
75MP0009703_decreased_birth_body0.93861823
76MP0003453_abnormal_keratinocyte_physiol0.93833746
77MP0004782_abnormal_surfactant_physiolog0.91990230
78MP0002254_reproductive_system_inflammat0.91336551
79MP0005623_abnormal_meninges_morphology0.89588937
80MP0002429_abnormal_blood_cell0.87661041
81MP0002697_abnormal_eye_size0.86872442
82MP0003315_abnormal_perineum_morphology0.86780016
83MP0003937_abnormal_limbs/digits/tail_de0.85894967
84MP0002925_abnormal_cardiovascular_devel0.85646349
85MP0005666_abnormal_adipose_tissue0.85395277
86MP0002932_abnormal_joint_morphology0.84729223
87MP0000858_altered_metastatic_potential0.82318367
88MP0005257_abnormal_intraocular_pressure0.81669272
89MP0003935_abnormal_craniofacial_develop0.79685502
90MP0000477_abnormal_intestine_morphology0.79546136
91MP0003283_abnormal_digestive_organ0.79321167
92MP0001853_heart_inflammation0.78297666
93MP0000566_synostosis0.78150181
94MP0000685_abnormal_immune_system0.77703347
95MP0002282_abnormal_trachea_morphology0.76336654
96MP0000358_abnormal_cell_content/0.76326227
97MP0001346_abnormal_lacrimal_gland0.75894273
98MP0001881_abnormal_mammary_gland0.75507525
99MP0000716_abnormal_immune_system0.75325639
100MP0003300_gastrointestinal_ulcer0.74749087
101MP0002938_white_spotting0.74737603
102MP0003385_abnormal_body_wall0.71822500
103MP0005384_cellular_phenotype0.70344424
104MP0005621_abnormal_cell_physiology0.69570585
105MP0000432_abnormal_head_morphology0.69436498
106MP0001286_abnormal_eye_development0.69315906
107MP0001216_abnormal_epidermal_layer0.69309905
108MP0003221_abnormal_cardiomyocyte_apopto0.68748441
109MP0000266_abnormal_heart_morphology0.68332998
110MP0002060_abnormal_skin_morphology0.68177829
111MP0000049_abnormal_middle_ear0.67737153
112MP0003718_maternal_effect0.67193098
113MP0003122_maternal_imprinting0.66959169
114MP0002249_abnormal_larynx_morphology0.66849206
115MP0009379_abnormal_foot_pigmentation0.65647938
116MP0000465_gastrointestinal_hemorrhage0.65478998
117MP0002210_abnormal_sex_determination0.65453033
118MP0008770_decreased_survivor_rate0.65430979
119MP0003942_abnormal_urinary_system0.65332826
120MP0004133_heterotaxia0.64661848
121MP0001800_abnormal_humoral_immune0.64419668
122MP0009697_abnormal_copulation0.63622871
123MP0003943_abnormal_hepatobiliary_system0.62869070
124MP0006035_abnormal_mitochondrial_morpho0.62846606
125MP0001145_abnormal_male_reproductive0.61609472
126MP0004233_abnormal_muscle_weight0.61483659
127MP0003861_abnormal_nervous_system0.60963883
128MP0010234_abnormal_vibrissa_follicle0.59373627
129MP0004264_abnormal_extraembryonic_tissu0.58939883
130MP0010630_abnormal_cardiac_muscle0.58455383

Predicted human phenotypes

RankGene SetZ-score
1Progressive muscle weakness (HP:0003323)3.45898994
2Selective tooth agenesis (HP:0001592)3.33306715
3Short 4th metacarpal (HP:0010044)3.32908362
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.32908362
5Ependymoma (HP:0002888)3.30317852
6Colon cancer (HP:0003003)3.19522225
7Increased nuchal translucency (HP:0010880)3.16204521
8Medulloblastoma (HP:0002885)3.03888995
9Spastic diplegia (HP:0001264)2.97066984
10Hyperacusis (HP:0010780)2.92538891
11Reticulocytopenia (HP:0001896)2.88944967
12Renal duplication (HP:0000075)2.87180196
13Microvesicular hepatic steatosis (HP:0001414)2.83721688
14Proximal placement of thumb (HP:0009623)2.83084086
15Abnormal number of incisors (HP:0011064)2.80346880
16Deviation of the thumb (HP:0009603)2.74394443
17Pseudobulbar signs (HP:0002200)2.72882610
18Patellar aplasia (HP:0006443)2.62714261
19Degeneration of anterior horn cells (HP:0002398)2.62585124
20Abnormality of the anterior horn cell (HP:0006802)2.62585124
21Birth length less than 3rd percentile (HP:0003561)2.58432363
22Progressive external ophthalmoplegia (HP:0000590)2.57470852
23Basal cell carcinoma (HP:0002671)2.54906150
24Volvulus (HP:0002580)2.52076362
25Cortical dysplasia (HP:0002539)2.50856329
26Aplasia/Hypoplasia of the patella (HP:0006498)2.50159648
27Abnormality of cells of the erythroid lineage (HP:0012130)2.50111604
28Abnormality of the 4th metacarpal (HP:0010012)2.47246881
29Long palpebral fissure (HP:0000637)2.44666732
30Urethral obstruction (HP:0000796)2.36247971
31Abnormal number of erythroid precursors (HP:0012131)2.35273583
32Achilles tendon contracture (HP:0001771)2.33399710
33High pitched voice (HP:0001620)2.29857445
34Atresia of the external auditory canal (HP:0000413)2.27519569
35Back pain (HP:0003418)2.24065579
36Broad distal phalanx of finger (HP:0009836)2.24023454
37Increased density of long bones (HP:0006392)2.21977232
38Long eyelashes (HP:0000527)2.20884919
39Neoplasm of the pancreas (HP:0002894)2.19444526
40Ragged-red muscle fibers (HP:0003200)2.15625299
41Abnormality of the fingertips (HP:0001211)2.14261590
42Rhabdomyosarcoma (HP:0002859)2.14238627
43Abnormality of the astrocytes (HP:0100707)2.13925796
44Astrocytoma (HP:0009592)2.13925796
45Missing ribs (HP:0000921)2.10811904
4611 pairs of ribs (HP:0000878)2.10096868
47Ulnar bowing (HP:0003031)2.08592328
48Deep palmar crease (HP:0006191)2.08589989
49Skin tags (HP:0010609)2.08313317
50Pelvic girdle muscle weakness (HP:0003749)2.07712345
51Prominent nose (HP:0000448)2.04763825
52Oral leukoplakia (HP:0002745)2.04388905
53Renovascular hypertension (HP:0100817)2.03439602
54Myelodysplasia (HP:0002863)2.02896951
55Abnormality of the calcaneus (HP:0008364)2.02796219
56Neoplasm of striated muscle (HP:0009728)2.01178590
57Ectopic kidney (HP:0000086)2.00833277
58Abnormality of chromosome stability (HP:0003220)2.00464065
59Thrombocytosis (HP:0001894)2.00448696
60Broad palm (HP:0001169)2.00080264
61Centrally nucleated skeletal muscle fibers (HP:0003687)1.97926126
62Preauricular skin tag (HP:0000384)1.96510784
63Meckel diverticulum (HP:0002245)1.96494413
64Overlapping toe (HP:0001845)1.95838026
65Trismus (HP:0000211)1.95443349
66Agnosia (HP:0010524)1.94218280
67Chromsome breakage (HP:0040012)1.93434787
68Glioma (HP:0009733)1.92170685
69Breast hypoplasia (HP:0003187)1.91931518
70Gastrointestinal carcinoma (HP:0002672)1.91660011
71Malignant gastrointestinal tract tumors (HP:0006749)1.91660011
72Overriding aorta (HP:0002623)1.91579946
73Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90795006
74Abnormality of the Achilles tendon (HP:0005109)1.90736826
75Elfin facies (HP:0004428)1.90214313
76Patellar dislocation (HP:0002999)1.89440033
77Amaurosis fugax (HP:0100576)1.89013045
78Orthostatic hypotension (HP:0001278)1.88766560
79Neoplasm of the oral cavity (HP:0100649)1.88427687
80Abnormality of the hip-girdle musculature (HP:0001445)1.88410779
81Multiple enchondromatosis (HP:0005701)1.87894259
82Pointed chin (HP:0000307)1.87184912
83Abnormality of the ileum (HP:0001549)1.86972179
84Abnormality of the salivary glands (HP:0010286)1.86909657
85Cutis marmorata (HP:0000965)1.86400212
86Bowel diverticulosis (HP:0005222)1.86388556
87Slender long bone (HP:0003100)1.84948411
88Tracheoesophageal fistula (HP:0002575)1.84113362
89Rough bone trabeculation (HP:0100670)1.83942317
90Duodenal stenosis (HP:0100867)1.83575056
91Small intestinal stenosis (HP:0012848)1.83575056
92Insidious onset (HP:0003587)1.83094351
93Termporal pattern (HP:0011008)1.83094351
94Abnormality of the distal phalanx of the thumb (HP:0009617)1.82125866
95Trigonocephaly (HP:0000243)1.81225725
96Aplasia/Hypoplasia of the uvula (HP:0010293)1.81052568
97Distal lower limb amyotrophy (HP:0008944)1.80888597
98Short 5th finger (HP:0009237)1.80811983
99Glossoptosis (HP:0000162)1.80482366
100Bicuspid aortic valve (HP:0001647)1.80075154
101Dysphonia (HP:0001618)1.79733427
102Cafe-au-lait spot (HP:0000957)1.79720095
103Abnormality of the umbilical cord (HP:0010881)1.79340178
104Aplastic anemia (HP:0001915)1.79323318
105Calcaneovalgus deformity (HP:0001848)1.79018003
106Facial cleft (HP:0002006)1.78973803
107Dysmetric saccades (HP:0000641)1.76770416
108Absent thumb (HP:0009777)1.76288310
109Skull defect (HP:0001362)1.75650975
110Secondary amenorrhea (HP:0000869)1.75120219
111Abnormality of the carotid arteries (HP:0005344)1.75011445
112Nephroblastoma (Wilms tumor) (HP:0002667)1.74678574
113Arnold-Chiari malformation (HP:0002308)1.74052941
114Pallor (HP:0000980)1.73094918
115Limb-girdle muscle atrophy (HP:0003797)1.72704320
116Squamous cell carcinoma (HP:0002860)1.72306104
117Aplasia/Hypoplasia of the sternum (HP:0006714)1.71825691
118Duplication of thumb phalanx (HP:0009942)1.70846320
119Abnormality of the phalanges of the hallux (HP:0010057)1.70298598
120Partial duplication of thumb phalanx (HP:0009944)1.69786415
121Cutaneous melanoma (HP:0012056)1.68470789
122Insomnia (HP:0100785)1.68313299
123Protrusio acetabuli (HP:0003179)1.67778786
124Ovarian neoplasm (HP:0100615)1.67461703
125High anterior hairline (HP:0009890)1.67392991
126Horseshoe kidney (HP:0000085)1.67334893
127Abnormal lung lobation (HP:0002101)1.67211887
128Disproportionate tall stature (HP:0001519)1.66292926
129Broad thumb (HP:0011304)1.65256355
130Shallow orbits (HP:0000586)1.65183056
131Intestinal polyp (HP:0005266)1.65017856
132Spina bifida occulta (HP:0003298)1.64919938
133Megalocornea (HP:0000485)1.64560642
134IgM deficiency (HP:0002850)1.64087541
135Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.63800200
136Shoulder girdle muscle weakness (HP:0003547)1.63777523
137Ankle contracture (HP:0006466)1.63731929
138Unilateral renal agenesis (HP:0000122)1.63616077
139Premature ovarian failure (HP:0008209)1.63011576
140Abnormality of the preputium (HP:0100587)1.62857326
141Sparse lateral eyebrow (HP:0005338)1.62830433
142Neoplasm of the colon (HP:0100273)1.62061645
143Biliary tract neoplasm (HP:0100574)1.61842468
144Deep philtrum (HP:0002002)1.61532127
145Chromosomal breakage induced by crosslinking agents (HP:0003221)1.61300238
146Abnormality of the peritoneum (HP:0002585)1.60925020
147Abnormality of the musculature of the pelvis (HP:0001469)1.60493257
148Progressive hearing impairment (HP:0001730)1.60117291
149Turricephaly (HP:0000262)1.59331645
150Flared metaphyses (HP:0003015)1.58775378
151Ankyloglossia (HP:0010296)1.58141785
152Neuroblastoma (HP:0003006)1.57661051
153Primitive neuroectodermal tumor (HP:0030065)1.57661051
154Neuroblastic tumors (HP:0004376)1.57661051
155Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.57661051
156Radioulnar synostosis (HP:0002974)1.55548186
157Embryonal renal neoplasm (HP:0011794)1.54911996
158Personality changes (HP:0000751)1.53142062
159Thoracic kyphosis (HP:0002942)1.53119422
160Syringomyelia (HP:0003396)1.53094595
161Spinal cord lesions (HP:0100561)1.53094595
162Breech presentation (HP:0001623)1.51933431
163Abnormality of reticulocytes (HP:0004312)1.51915976
164Single umbilical artery (HP:0001195)1.51046051
165Abnormality of the fetal cardiovascular system (HP:0010948)1.51046051

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.17300800
2SMG13.80073122
3MAP3K103.31612487
4EEF2K3.23120957
5BUB12.95244641
6CDK122.85993376
7NEK22.81992372
8WEE12.78738039
9PASK2.54427050
10VRK22.39551427
11PKN22.39540152
12TSSK62.09220744
13TRIB32.03972405
14RPS6KB21.89776480
15SRPK11.88986443
16MKNK11.85809928
17EIF2AK11.84316203
18TTK1.84113099
19NEK11.83737638
20STK101.79471506
21RPS6KA41.74121272
22TGFBR11.72679938
23PRPF4B1.72272288
24LATS21.68048040
25CDK41.67816775
26ATR1.67572077
27TESK21.65270250
28MAP4K11.59406321
29CDK71.54194737
30BRD41.54051126
31PAK41.52169584
32AURKB1.46010247
33TAF11.45533997
34PLK11.40913133
35MAP3K81.40339933
36DYRK31.38028095
37LRRK21.29642189
38IRAK31.29077192
39ACVR1B1.28324290
40SCYL21.27594888
41* CHEK11.19463304
42BRSK21.16700072
43CDK61.15881448
44MKNK21.15045673
45ALK1.13578151
46PBK1.09125578
47PTK61.07559911
48ARAF1.07059006
49PLK31.04386471
50STK41.00995092
51PLK40.97899112
52TTN0.96690556
53CHEK20.94663067
54FLT30.94228496
55NME20.93839273
56MTOR0.88796311
57CDK20.87800491
58ATM0.86691387
59SIK10.85962508
60FGFR40.83888903
61BTK0.78485480
62TESK10.77842292
63PDGFRA0.76742733
64PAK20.76041510
65CLK10.75308881
66AURKA0.74233466
67MAP2K30.72839802
68BRSK10.72735767
69VRK10.71748479
70GRK60.70928711
71FGFR10.70131639
72MAP3K140.70043532
73PIM10.68142448
74KDR0.67744700
75CDK11A0.66798479
76EIF2AK30.65187150
77BRAF0.64844070
78ZAP700.64074331
79MAP3K130.63767395
80CDK10.62519183
81CAMK1D0.61074832
82STK30.60501741
83MAPKAPK30.59649561
84CDK150.57739200
85ILK0.57299455
86TLK10.57085358
87MAP2K20.56646842
88MELK0.55055147
89AKT20.54729912
90CDK180.54372411
91CSNK2A20.53130064
92PAK10.52389382
93CDK140.52190369
94CDK190.51865377
95RIPK10.49981524
96SIK20.49438925
97CSF1R0.48357097
98JAK30.47127426
99STK240.46173529
100DAPK10.45483167
101BMX0.45211519
102CAMK1G0.44975181
103ICK0.44792220
104ERBB30.43777019
105EIF2AK20.43580437
106PRKDC0.43474534
107PIM20.42922448
108DYRK1B0.42697660
109STK160.42651719
110ERBB40.42044674
111EPHA20.40695518
112CHUK0.40587033
113LATS10.40485124
114CDK80.40364441
115CSNK2A10.40325998
116CCNB10.39465628
117ERN10.37941189
118CSNK1E0.37158945
119MAP3K110.35746909
120MAP3K90.34981002
121BLK0.34630646
122ITK0.33653110
123TAOK20.33123981
124RPS6KC10.33044871
125RPS6KL10.33044871
126MOS0.32926087
127MAPK140.32565869
128MARK30.32276042
129CDK90.32029355
130RPS6KA10.30654399
131MAPKAPK20.30274757

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.76761531
2Mismatch repair_Homo sapiens_hsa034303.79760002
3* Spliceosome_Homo sapiens_hsa030403.60000880
4RNA transport_Homo sapiens_hsa030132.98747577
5Base excision repair_Homo sapiens_hsa034102.94849337
6Cell cycle_Homo sapiens_hsa041102.86293968
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.79066966
8Ribosome_Homo sapiens_hsa030102.49713530
9One carbon pool by folate_Homo sapiens_hsa006702.49122323
10Nucleotide excision repair_Homo sapiens_hsa034202.40891167
11Homologous recombination_Homo sapiens_hsa034402.39764342
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.37111869
13mRNA surveillance pathway_Homo sapiens_hsa030152.15120769
14Non-homologous end-joining_Homo sapiens_hsa034501.96395213
15Proteasome_Homo sapiens_hsa030501.78841695
16RNA degradation_Homo sapiens_hsa030181.69157377
17RNA polymerase_Homo sapiens_hsa030201.69143852
18Fanconi anemia pathway_Homo sapiens_hsa034601.69046770
19Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.67500886
20Pyrimidine metabolism_Homo sapiens_hsa002401.65766656
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.61937548
22p53 signaling pathway_Homo sapiens_hsa041151.55541041
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.50885557
24Antigen processing and presentation_Homo sapiens_hsa046121.34997266
25Epstein-Barr virus infection_Homo sapiens_hsa051691.31597961
26Viral carcinogenesis_Homo sapiens_hsa052031.30504873
27HTLV-I infection_Homo sapiens_hsa051661.28386235
28Chronic myeloid leukemia_Homo sapiens_hsa052201.24332447
29Herpes simplex infection_Homo sapiens_hsa051681.21960280
30Small cell lung cancer_Homo sapiens_hsa052221.19289580
31MicroRNAs in cancer_Homo sapiens_hsa052061.18932422
32Basal transcription factors_Homo sapiens_hsa030221.12664622
33Primary immunodeficiency_Homo sapiens_hsa053401.11352866
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.11064461
35Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10630138
36Basal cell carcinoma_Homo sapiens_hsa052171.10095912
37Notch signaling pathway_Homo sapiens_hsa043301.08268334
38Thyroid cancer_Homo sapiens_hsa052161.01750942
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01098082
40Systemic lupus erythematosus_Homo sapiens_hsa053220.99591542
41Colorectal cancer_Homo sapiens_hsa052100.97352420
42Oocyte meiosis_Homo sapiens_hsa041140.91724034
43Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90566777
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88080619
45Viral myocarditis_Homo sapiens_hsa054160.87860114
46Legionellosis_Homo sapiens_hsa051340.87766805
47Hippo signaling pathway_Homo sapiens_hsa043900.85662685
48Fructose and mannose metabolism_Homo sapiens_hsa000510.84347792
49Selenocompound metabolism_Homo sapiens_hsa004500.83774061
50Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.83716521
51Apoptosis_Homo sapiens_hsa042100.79234409
52Hepatitis B_Homo sapiens_hsa051610.77753863
53Lysine degradation_Homo sapiens_hsa003100.76353133
54Adherens junction_Homo sapiens_hsa045200.75520434
55Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.74868063
56Central carbon metabolism in cancer_Homo sapiens_hsa052300.74343848
57Measles_Homo sapiens_hsa051620.73724243
58Non-small cell lung cancer_Homo sapiens_hsa052230.72595916
59Acute myeloid leukemia_Homo sapiens_hsa052210.72373559
60Galactose metabolism_Homo sapiens_hsa000520.72299084
61Biosynthesis of amino acids_Homo sapiens_hsa012300.71187544
62Bladder cancer_Homo sapiens_hsa052190.70197047
63Shigellosis_Homo sapiens_hsa051310.69725650
64Prion diseases_Homo sapiens_hsa050200.67704402
65Proteoglycans in cancer_Homo sapiens_hsa052050.66471636
66Purine metabolism_Homo sapiens_hsa002300.66239384
67Folate biosynthesis_Homo sapiens_hsa007900.66083087
68Hedgehog signaling pathway_Homo sapiens_hsa043400.65857981
69B cell receptor signaling pathway_Homo sapiens_hsa046620.65737187
70TGF-beta signaling pathway_Homo sapiens_hsa043500.65254524
71Pyruvate metabolism_Homo sapiens_hsa006200.65150713
72NF-kappa B signaling pathway_Homo sapiens_hsa040640.64190527
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64148052
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63798021
75mTOR signaling pathway_Homo sapiens_hsa041500.62480769
76Pathways in cancer_Homo sapiens_hsa052000.60958140
77Pancreatic cancer_Homo sapiens_hsa052120.60360149
78Pentose phosphate pathway_Homo sapiens_hsa000300.59176867
79Leukocyte transendothelial migration_Homo sapiens_hsa046700.57955768
80Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.55703900
81T cell receptor signaling pathway_Homo sapiens_hsa046600.54564740
82Cyanoamino acid metabolism_Homo sapiens_hsa004600.53796067
83Renal cell carcinoma_Homo sapiens_hsa052110.53787395
84Endometrial cancer_Homo sapiens_hsa052130.53433849
85Prostate cancer_Homo sapiens_hsa052150.52372156
86Leishmaniasis_Homo sapiens_hsa051400.51534829
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.51298107
88N-Glycan biosynthesis_Homo sapiens_hsa005100.50972483
89HIF-1 signaling pathway_Homo sapiens_hsa040660.49598616
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49481386
91AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.49232848
92Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48795741
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.48166320
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.47724120
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47718711
96Influenza A_Homo sapiens_hsa051640.47135115
97Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46495376
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.45902633
99Salmonella infection_Homo sapiens_hsa051320.44416462
100Wnt signaling pathway_Homo sapiens_hsa043100.41513932
101Toxoplasmosis_Homo sapiens_hsa051450.41176052
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40406086
103Hematopoietic cell lineage_Homo sapiens_hsa046400.39671618
104Vitamin B6 metabolism_Homo sapiens_hsa007500.38228386
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38123227
106Tight junction_Homo sapiens_hsa045300.37921034
107Focal adhesion_Homo sapiens_hsa045100.37330559
108Drug metabolism - other enzymes_Homo sapiens_hsa009830.37074832
109Insulin signaling pathway_Homo sapiens_hsa049100.36153863
110Alcoholism_Homo sapiens_hsa050340.35244705
111NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34404911
112VEGF signaling pathway_Homo sapiens_hsa043700.33876481
113Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33806715
114Hepatitis C_Homo sapiens_hsa051600.32834801
115Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.32776797
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.31149914
117AMPK signaling pathway_Homo sapiens_hsa041520.31024024
118ErbB signaling pathway_Homo sapiens_hsa040120.30878530
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.30347823
120Sulfur relay system_Homo sapiens_hsa041220.30300583
121FoxO signaling pathway_Homo sapiens_hsa040680.28467539
122Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.28224476
123Jak-STAT signaling pathway_Homo sapiens_hsa046300.28033251
124Carbon metabolism_Homo sapiens_hsa012000.27920806
125Intestinal immune network for IgA production_Homo sapiens_hsa046720.27569472

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