HNRNPA3P9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1rRNA methylation (GO:0031167)6.09421768
2negative regulation of calcium ion-dependent exocytosis (GO:0045955)5.81703901
3positive regulation of male gonad development (GO:2000020)5.63408648
4rRNA modification (GO:0000154)5.48254472
5positive regulation of granulocyte differentiation (GO:0030854)5.08152334
6negative regulation of neurotransmitter secretion (GO:0046929)4.90182697
7DNA replication checkpoint (GO:0000076)4.85381098
8regulation of male gonad development (GO:2000018)4.58628952
9regulation of establishment of cell polarity (GO:2000114)4.55055353
10negative regulation of granulocyte differentiation (GO:0030853)4.43871843
11pericardium development (GO:0060039)4.31354453
12erythrocyte development (GO:0048821)4.31224055
13monoubiquitinated protein deubiquitination (GO:0035520)4.29675087
14glucocorticoid receptor signaling pathway (GO:0042921)4.19748256
15cytoplasmic mRNA processing body assembly (GO:0033962)4.07252992
16erythrocyte maturation (GO:0043249)4.00886692
17protein localization to kinetochore (GO:0034501)3.92264932
18mitotic sister chromatid cohesion (GO:0007064)3.89053694
19histone-serine phosphorylation (GO:0035404)3.86519779
20regulation of granulocyte differentiation (GO:0030852)3.82744453
21nuclear pore complex assembly (GO:0051292)3.82209449
22nerve growth factor signaling pathway (GO:0038180)3.78195623
23positive regulation of developmental pigmentation (GO:0048087)3.65428269
24SMAD protein complex assembly (GO:0007183)3.56609414
25termination of RNA polymerase III transcription (GO:0006386)3.54142303
26transcription elongation from RNA polymerase III promoter (GO:0006385)3.54142303
27mitotic chromosome condensation (GO:0007076)3.53773094
28protein localization to chromosome, centromeric region (GO:0071459)3.47357761
29granulocyte differentiation (GO:0030851)3.44424066
30microtubule polymerization or depolymerization (GO:0031109)3.44218201
31respiratory chain complex IV assembly (GO:0008535)3.37028299
32prenylation (GO:0097354)3.35298828
33protein prenylation (GO:0018342)3.35298828
34regulation of DNA endoreduplication (GO:0032875)3.34983016
35negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.31529315
36sister chromatid segregation (GO:0000819)3.27815059
37regulation of establishment or maintenance of cell polarity (GO:0032878)3.23325779
38positive regulation of mRNA processing (GO:0050685)3.20791572
39negative regulation of neurotransmitter transport (GO:0051589)3.18334699
40mitotic sister chromatid segregation (GO:0000070)3.10841788
41definitive hemopoiesis (GO:0060216)3.08527731
42microtubule depolymerization (GO:0007019)3.06010162
43rRNA catabolic process (GO:0016075)3.05460886
44nodal signaling pathway (GO:0038092)3.04845507
45centriole replication (GO:0007099)3.04335914
46corticosteroid receptor signaling pathway (GO:0031958)3.01308896
47peptidyl-histidine modification (GO:0018202)3.00399450
48positive regulation of hair cycle (GO:0042635)3.00123701
49positive regulation of hair follicle development (GO:0051798)3.00123701
50replication fork processing (GO:0031297)2.99279780
51attachment of spindle microtubules to kinetochore (GO:0008608)2.95603869
52nuclear pore organization (GO:0006999)2.94007753
53mast cell degranulation (GO:0043303)2.93935211
54mast cell activation involved in immune response (GO:0002279)2.93935211
55regulation of centriole replication (GO:0046599)2.93114557
56regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.87520124
57positive regulation of Rap GTPase activity (GO:0032854)2.86974588
58endocardial cushion development (GO:0003197)2.86700576
59mitotic spindle checkpoint (GO:0071174)2.85665770
60cell differentiation involved in embryonic placenta development (GO:0060706)2.84555154
61positive regulation of vasculogenesis (GO:2001214)2.83134302
62Rap protein signal transduction (GO:0032486)2.82718231
63nucleotide-excision repair, DNA gap filling (GO:0006297)2.82184156
64regulation of RNA export from nucleus (GO:0046831)2.82136286
65DNA topological change (GO:0006265)2.81634371
66positive regulation of cellular response to oxidative stress (GO:1900409)2.81489344
67positive regulation of response to oxidative stress (GO:1902884)2.81489344
68negative regulation of myeloid cell apoptotic process (GO:0033033)2.80927500
69positive regulation of mRNA metabolic process (GO:1903313)2.79931781
70pore complex assembly (GO:0046931)2.77527752
71spindle checkpoint (GO:0031577)2.77009328
72peptidyl-lysine methylation (GO:0018022)2.76895723
73positive regulation of mRNA 3-end processing (GO:0031442)2.75302932
74regulation of pigment cell differentiation (GO:0050932)2.74299977
75double-strand break repair via homologous recombination (GO:0000724)2.71960416
76DNA synthesis involved in DNA repair (GO:0000731)2.70239857
77T cell lineage commitment (GO:0002360)2.69994370
78V(D)J recombination (GO:0033151)2.69054228
79nonmotile primary cilium assembly (GO:0035058)2.69004852
80pseudouridine synthesis (GO:0001522)2.68489843
81negative regulation of glial cell proliferation (GO:0060253)2.67082678
82DNA replication-dependent nucleosome assembly (GO:0006335)2.66255077
83DNA replication-dependent nucleosome organization (GO:0034723)2.66255077
84recombinational repair (GO:0000725)2.65686287
85positive regulation of steroid hormone secretion (GO:2000833)2.64511702
86regulation of penile erection (GO:0060405)2.63794205
87negative regulation of chromosome segregation (GO:0051985)2.62159351
88histone deubiquitination (GO:0016578)2.61816648
89cranial suture morphogenesis (GO:0060363)2.61661096
90left/right axis specification (GO:0070986)2.59293104
91peptidyl-lysine trimethylation (GO:0018023)2.59259277
92mitotic nuclear envelope disassembly (GO:0007077)2.58827666
93endoderm formation (GO:0001706)2.58634497
94regulation of female gonad development (GO:2000194)2.58202431
95protein heterotetramerization (GO:0051290)2.57030587
96mitotic recombination (GO:0006312)2.56740397
97response to UV-C (GO:0010225)2.52228478
98coronary vasculature morphogenesis (GO:0060977)2.51749591
99trophectodermal cell differentiation (GO:0001829)2.51303863
100response to pheromone (GO:0019236)10.2847378

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.59532848
2E2F4_17652178_ChIP-ChIP_JURKAT_Human5.05845732
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.49497584
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.34705600
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.11548574
6NOTCH1_21737748_ChIP-Seq_TLL_Human2.87879889
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.74228291
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.69510856
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.68248595
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.57736882
11KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.53721936
12E2F1_21310950_ChIP-Seq_MCF-7_Human2.46576672
13ELK1_19687146_ChIP-ChIP_HELA_Human2.43307853
14VDR_23849224_ChIP-Seq_CD4+_Human2.40497315
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.40198711
16CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.38035226
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.34330879
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.30391391
19EWS_26573619_Chip-Seq_HEK293_Human2.26625299
20RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.25338892
21AR_21909140_ChIP-Seq_LNCAP_Human2.16144725
22GABP_17652178_ChIP-ChIP_JURKAT_Human2.07029004
23IRF1_19129219_ChIP-ChIP_H3396_Human2.00133724
24FOXP3_21729870_ChIP-Seq_TREG_Human1.93182288
25MYC_18940864_ChIP-ChIP_HL60_Human1.92758168
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.86321467
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.85898159
28ER_23166858_ChIP-Seq_MCF-7_Human1.77705676
29POU3F2_20337985_ChIP-ChIP_501MEL_Human1.77425126
30CREB1_15753290_ChIP-ChIP_HEK293T_Human1.76993940
31ZNF274_21170338_ChIP-Seq_K562_Hela1.75973269
32PADI4_21655091_ChIP-ChIP_MCF-7_Human1.73958913
33ETS1_20019798_ChIP-Seq_JURKAT_Human1.70732570
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58823227
35GBX2_23144817_ChIP-Seq_PC3_Human1.58384435
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.58077840
37CIITA_25753668_ChIP-Seq_RAJI_Human1.56302951
38VDR_22108803_ChIP-Seq_LS180_Human1.54836855
39IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.52231271
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.50635281
41E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.48604737
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.48085381
43KDM5A_27292631_Chip-Seq_BREAST_Human1.46778273
44FUS_26573619_Chip-Seq_HEK293_Human1.46139244
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45105050
46IRF8_22096565_ChIP-ChIP_GC-B_Human1.41695035
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.40307112
48SMAD_19615063_ChIP-ChIP_OVARY_Human1.35050753
49BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.33853777
50TP53_18474530_ChIP-ChIP_U2OS_Human1.29536493
51MYB_26560356_Chip-Seq_TH2_Human1.26079734
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.25144230
53MYB_26560356_Chip-Seq_TH1_Human1.24808493
54STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.18728186
55HIF1A_21447827_ChIP-Seq_MCF-7_Human1.18230984
56MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.17869318
57TTF2_22483619_ChIP-Seq_HELA_Human1.11970448
58MYC_22102868_ChIP-Seq_BL_Human1.10143387
59STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.07970662
60MYC_19030024_ChIP-ChIP_MESCs_Mouse1.04073153
61PKCTHETA_26484144_Chip-Seq_BREAST_Human1.01839603
62YY1_21170310_ChIP-Seq_MESCs_Mouse1.01765030
63DCP1A_22483619_ChIP-Seq_HELA_Human1.00837356
64RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.00457754
65TAF15_26573619_Chip-Seq_HEK293_Human0.99897128
66PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98750687
67POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97697989
68SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97685821
69JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97094348
70NELFA_20434984_ChIP-Seq_ESCs_Mouse0.96664174
71FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.96406226
72CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.96258169
73HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95237561
74ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.94351774
75FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.94289512
76FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.92972260
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.92303715
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92132181
79MYC_19079543_ChIP-ChIP_MESCs_Mouse0.91116101
80TP53_16413492_ChIP-PET_HCT116_Human0.90952317
81STAT3_23295773_ChIP-Seq_U87_Human0.89364519
82CRX_20693478_ChIP-Seq_RETINA_Mouse0.89140444
83SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.88741065
84TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87994721
85EZH2_27294783_Chip-Seq_NPCs_Mouse0.87942263
86MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87267435
87NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.85696057
88SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.84746635
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84590465
90AUTS2_25519132_ChIP-Seq_293T-REX_Human0.84299030
91SALL4_22934838_ChIP-ChIP_CD34+_Human0.83656553
92GATA3_26560356_Chip-Seq_TH2_Human0.83638922
93SCL_19346495_ChIP-Seq_HPC-7_Human0.82834650
94MYC_18358816_ChIP-ChIP_MESCs_Mouse0.82631200
95HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.82216866
96RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.81999719
97ELF1_17652178_ChIP-ChIP_JURKAT_Human0.81662277
98BRD4_25478319_ChIP-Seq_HGPS_Human0.81335316
99CTBP1_25329375_ChIP-Seq_LNCAP_Human0.81139225
100ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.80870739

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003123_paternal_imprinting6.61213593
2MP0008057_abnormal_DNA_replication3.63092494
3MP0002396_abnormal_hematopoietic_system3.45220711
4MP0003693_abnormal_embryo_hatching3.10536827
5MP0003787_abnormal_imprinting3.04469230
6MP0010094_abnormal_chromosome_stability2.99912378
7MP0004808_abnormal_hematopoietic_stem2.57461773
8MP0009697_abnormal_copulation2.53860719
9MP0008058_abnormal_DNA_repair2.18412415
10MP0008995_early_reproductive_senescence2.15149214
11MP0003890_abnormal_embryonic-extraembry2.13238913
12MP0000516_abnormal_urinary_system2.06283242
13MP0005367_renal/urinary_system_phenotyp2.06283242
14MP0005646_abnormal_pituitary_gland2.03819884
15MP0003763_abnormal_thymus_physiology1.98700226
16MP0003111_abnormal_nucleus_morphology1.95660433
17MP0000537_abnormal_urethra_morphology1.90878378
18MP0004957_abnormal_blastocyst_morpholog1.83204671
19MP0003195_calcinosis1.62336870
20MP0003077_abnormal_cell_cycle1.60718313
21MP0005671_abnormal_response_to1.57539586
22MP0003943_abnormal_hepatobiliary_system1.55922958
23MP0001529_abnormal_vocalization1.54602603
24MP0001727_abnormal_embryo_implantation1.54370236
25MP0000639_abnormal_adrenal_gland1.35542765
26MP0004142_abnormal_muscle_tone1.32068445
27MP0003119_abnormal_digestive_system1.27805900
28MP0003121_genomic_imprinting1.27544121
29MP0000490_abnormal_crypts_of1.25982306
30MP0008932_abnormal_embryonic_tissue1.25809431
31MP0003942_abnormal_urinary_system1.25648225
32MP0000703_abnormal_thymus_morphology1.21852886
33MP0005076_abnormal_cell_differentiation1.19576330
34MP0010030_abnormal_orbit_morphology1.18739650
35MP0005360_urolithiasis1.17717098
36MP0001790_abnormal_immune_system1.16652402
37MP0005387_immune_system_phenotype1.16652402
38MP0003786_premature_aging1.15066582
39MP0000372_irregular_coat_pigmentation1.11587654
40MP0002398_abnormal_bone_marrow1.09134029
41MP0004197_abnormal_fetal_growth/weight/1.08642803
42MP0003656_abnormal_erythrocyte_physiolo1.07391670
43MP0002019_abnormal_tumor_incidence1.06952285
44MP0005451_abnormal_body_composition1.06268201
45MP0002166_altered_tumor_susceptibility1.05357094
46MP0001697_abnormal_embryo_size1.04815787
47MP0000566_synostosis1.03947536
48MP0003936_abnormal_reproductive_system1.03729275
49MP0009384_cardiac_valve_regurgitation1.01946761
50MP0000733_abnormal_muscle_development1.01756391
51MP0001730_embryonic_growth_arrest1.01555225
52MP0008961_abnormal_basal_metabolism1.00396636
53MP0000689_abnormal_spleen_morphology1.00379276
54MP0000631_abnormal_neuroendocrine_gland0.95091228
55MP0002086_abnormal_extraembryonic_tissu0.93254788
56MP0006035_abnormal_mitochondrial_morpho0.93201949
57MP0002822_catalepsy0.92551398
58MP0002638_abnormal_pupillary_reflex0.92515090
59MP0002722_abnormal_immune_system0.91826308
60MP0006036_abnormal_mitochondrial_physio0.90801453
61MP0000313_abnormal_cell_death0.90709238
62MP0001800_abnormal_humoral_immune0.89908060
63MP0001919_abnormal_reproductive_system0.87232395
64MP0002006_tumorigenesis0.86493245
65MP0001346_abnormal_lacrimal_gland0.85550180
66MP0004947_skin_inflammation0.85442172
67MP0000350_abnormal_cell_proliferation0.84223385
68MP0001191_abnormal_skin_condition0.84028149
69MP0002088_abnormal_embryonic_growth/wei0.83622627
70MP0003984_embryonic_growth_retardation0.83003337
71MP0000358_abnormal_cell_content/0.81920970
72MP0010307_abnormal_tumor_latency0.81055272
73MP0001835_abnormal_antigen_presentation0.80709759
74MP0003315_abnormal_perineum_morphology0.80485146
75MP0005389_reproductive_system_phenotype0.80461725
76MP0008789_abnormal_olfactory_epithelium0.80413854
77MP0003718_maternal_effect0.78769231
78MP0001672_abnormal_embryogenesis/_devel0.78696483
79MP0005380_embryogenesis_phenotype0.78696483
80MP0001929_abnormal_gametogenesis0.78643826
81MP0000716_abnormal_immune_system0.78639616
82MP0006292_abnormal_olfactory_placode0.78214751
83MP0004185_abnormal_adipocyte_glucose0.78009595
84MP0002210_abnormal_sex_determination0.76734031
85MP0005310_abnormal_salivary_gland0.71566757
86MP0002751_abnormal_autonomic_nervous0.70986803
87MP0002429_abnormal_blood_cell0.70623691
88MP0000371_diluted_coat_color0.70464767
89MP0001873_stomach_inflammation0.69901862
90MP0001119_abnormal_female_reproductive0.69495939
91MP0000858_altered_metastatic_potential0.68986151
92MP0009053_abnormal_anal_canal0.68830775
93MP0002080_prenatal_lethality0.68462458
94MP0002160_abnormal_reproductive_system0.67345754
95MP0002084_abnormal_developmental_patter0.67263064
96MP0008007_abnormal_cellular_replicative0.65736092
97MP0006072_abnormal_retinal_apoptosis0.64853011
98MP0001501_abnormal_sleep_pattern0.64697363
99MP0000627_abnormal_mammary_gland0.63432052
100MP0005397_hematopoietic_system_phenotyp0.62930432

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.15981364
2Septate vagina (HP:0001153)4.38434934
3Genetic anticipation (HP:0003743)4.02598098
4Abnormality of the pons (HP:0007361)3.60061606
5Cerebellar dysplasia (HP:0007033)3.57823633
6Chromsome breakage (HP:0040012)3.38083179
7T lymphocytopenia (HP:0005403)3.29870272
8Hypoplasia of the pons (HP:0012110)3.29722328
9Hypoplasia of the thymus (HP:0000778)3.24548200
10Stenosis of the external auditory canal (HP:0000402)3.21588428
11Chronic diarrhea (HP:0002028)3.10438468
12Acute myeloid leukemia (HP:0004808)3.01628189
13Abnormality of T cell number (HP:0011839)2.83218317
14Gaze-evoked nystagmus (HP:0000640)2.82799234
15Severe combined immunodeficiency (HP:0004430)2.79481697
16Chromosomal breakage induced by crosslinking agents (HP:0003221)2.76551814
17Acanthocytosis (HP:0001927)2.74694577
18Overlapping toe (HP:0001845)2.72845565
19Type II lissencephaly (HP:0007260)2.63682836
20Flat occiput (HP:0005469)2.54514550
21Ectopic kidney (HP:0000086)2.52312481
22Progressive cerebellar ataxia (HP:0002073)2.50081969
23Abnormality of the fingertips (HP:0001211)2.47891708
24Fair hair (HP:0002286)2.45640512
25Brushfield spots (HP:0001088)2.41708281
26Abnormality of chromosome stability (HP:0003220)2.40653549
27Acute lymphatic leukemia (HP:0006721)2.40256132
28Combined immunodeficiency (HP:0005387)2.39949536
29Chronic hepatic failure (HP:0100626)2.29978932
30Upper limb muscle weakness (HP:0003484)2.23371455
31Increased hepatocellular lipid droplets (HP:0006565)2.22548531
32Aplasia cutis congenita (HP:0001057)2.22148705
33Hypoplasia of the uterus (HP:0000013)2.21709197
34Protruding tongue (HP:0010808)2.21479768
35IgA deficiency (HP:0002720)2.20561618
36Abnormality of the labia majora (HP:0012881)2.19232139
37Multiple enchondromatosis (HP:0005701)2.18655684
38Intestinal fistula (HP:0100819)2.17712542
39Abnormality of DNA repair (HP:0003254)2.16176192
40Poikilocytosis (HP:0004447)2.15331626
41Molar tooth sign on MRI (HP:0002419)2.13024224
42Abnormality of midbrain morphology (HP:0002418)2.13024224
43Abnormality of T cells (HP:0002843)2.10250965
44Female pseudohermaphroditism (HP:0010458)2.04503779
45Medial flaring of the eyebrow (HP:0010747)2.04007080
46Poikiloderma (HP:0001029)2.03686234
47Aplasia/Hypoplasia of the uvula (HP:0010293)2.02928432
48Breast hypoplasia (HP:0003187)2.02836187
49Prominent nose (HP:0000448)2.02148651
50Clumsiness (HP:0002312)2.01615457
51IgG deficiency (HP:0004315)2.01070427
52Hypoplastic labia majora (HP:0000059)2.00937349
53Overriding aorta (HP:0002623)1.97100928
54Anal stenosis (HP:0002025)1.96313010
55Aplasia/Hypoplasia of the thymus (HP:0010515)1.95659169
56Deep philtrum (HP:0002002)1.94408043
57Facial hemangioma (HP:0000329)1.94398158
58Abnormality of the nasal septum (HP:0000419)1.93987654
59Degeneration of the lateral corticospinal tracts (HP:0002314)1.92422555
60Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.92422555
61Abnormality of the labia minora (HP:0012880)1.92153399
62Large for gestational age (HP:0001520)1.90269857
63Thyroiditis (HP:0100646)1.88875465
64Rectovaginal fistula (HP:0000143)1.88527360
65Rectal fistula (HP:0100590)1.88527360
66Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.88195389
67Menstrual irregularities (HP:0000858)1.87733808
68Abnormality of the carotid arteries (HP:0005344)1.86134714
69Reticulocytopenia (HP:0001896)1.84743004
70Myelodysplasia (HP:0002863)1.84741955
71Concave nail (HP:0001598)1.83716461
72Obsessive-compulsive behavior (HP:0000722)1.83614012
73Increased number of teeth (HP:0011069)1.83203182
74Partial agenesis of the corpus callosum (HP:0001338)1.83053270
75Long eyelashes (HP:0000527)1.81691655
76Ankyloglossia (HP:0010296)1.80572296
77Recurrent viral infections (HP:0004429)1.79524811
78True hermaphroditism (HP:0010459)1.77373993
79Gonadal dysgenesis (HP:0000133)1.76171711
80Lipid accumulation in hepatocytes (HP:0006561)1.75748313
81Constricted visual fields (HP:0001133)1.75490610
82Congenital primary aphakia (HP:0007707)1.75395755
83Nephronophthisis (HP:0000090)1.74782290
84Hypoplastic left heart (HP:0004383)1.74688035
85Sandal gap (HP:0001852)1.74204224
86Poor coordination (HP:0002370)1.74174186
87Triphalangeal thumb (HP:0001199)1.73710037
88Generalized hypopigmentation of hair (HP:0011358)1.73568469
89Abnormality of the preputium (HP:0100587)1.71532692
90Breast aplasia (HP:0100783)1.71096824
91Fatigue (HP:0012378)1.70150496
92Short chin (HP:0000331)1.69703441
93Clubbing of toes (HP:0100760)1.67594342
94Submucous cleft hard palate (HP:0000176)1.67460457
95Spinal canal stenosis (HP:0003416)1.67301928
96Hypoplastic heart (HP:0001961)1.67241413
97Esophageal atresia (HP:0002032)1.66933287
98Abnormality of the renal cortex (HP:0011035)1.66413587
99Diastasis recti (HP:0001540)1.65260192
100Abnormality of the renal medulla (HP:0100957)1.63679395

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ZAK6.74456956
2TLK15.00011358
3BMPR1B4.55724068
4BRD43.93653921
5ACVR1B3.31429760
6TNIK2.98759148
7MST42.81695843
8MKNK22.71343802
9TNK22.50483967
10PLK42.19372243
11CDK122.17146346
12AKT32.08829837
13VRK12.06801342
14BRSK22.00790944
15TGFBR11.93291133
16CDC71.88520399
17PDK21.84926344
18MAP3K131.80353519
19CDK81.74649708
20SCYL21.55745160
21MAP3K41.48788917
22MELK1.43765722
23FRK1.43738903
24MKNK11.41139457
25WEE11.38342316
26NEK91.21672170
27MAP3K101.07041990
28TTK1.06388597
29PLK11.01477686
30CDK70.98137883
31TEC0.95849475
32CSNK1A1L0.94728310
33PIK3CG0.91136848
34RPS6KA40.89819809
35ATR0.87095106
36PBK0.87079589
37MAPK110.86695397
38SRPK10.85294589
39CDK60.79671894
40CSNK1G30.79493280
41PIM10.78749327
42MAP2K10.78077133
43CSNK1G10.75390719
44CHEK20.73240610
45EIF2AK30.70798052
46ERBB40.68978795
47ATM0.68566476
48MAP4K10.68244822
49ICK0.68061997
50KSR20.68003401
51RAF10.65216006
52MAP3K140.64627765
53BRSK10.62969908
54TAOK30.62523730
55TRIM280.62174221
56CAMK1G0.61458309
57NEK20.61014099
58CAMK1D0.58947672
59CSNK1G20.58794452
60MAP3K20.56620425
61PRKCQ0.55439046
62NLK0.54889870
63MAP2K70.48763412
64PDGFRB0.48746045
65AURKB0.48286090
66RPS6KA50.46189907
67PKN10.46136716
68CDK10.45374543
69FGFR10.45099732
70CDK40.44149245
71NEK60.42060131
72EIF2AK10.41951930
73CCNB10.41510605
74CDK20.40382626
75PLK30.39392418
76KSR10.38993563
77CDK30.37850312
78CHEK10.36734499
79CDK90.35823649
80PLK20.34601016
81ADRBK10.33053050
82PRKCE0.31240592
83TYRO30.30999989
84CAMKK20.30914342
85PRKDC0.30200632
86MAP3K70.30014157
87TRPM70.29494709
88GRK70.27251589
89GSK3B0.27071028
90MAPK140.26173408
91ALK0.25239971
92BMPR20.23435906
93CSNK1E0.21474597
94OBSCN0.21380450
95MTOR0.21247791
96JAK10.21129698
97TSSK60.20070274
98EIF2AK20.18924289
99NEK10.18613201
100PRKG20.17998277

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA polymerase_Homo sapiens_hsa030204.89621756
2Homologous recombination_Homo sapiens_hsa034403.79618314
3Nitrogen metabolism_Homo sapiens_hsa009102.77636533
4Mismatch repair_Homo sapiens_hsa034302.68123554
5Non-homologous end-joining_Homo sapiens_hsa034502.62628123
6DNA replication_Homo sapiens_hsa030302.61727364
7Fanconi anemia pathway_Homo sapiens_hsa034602.38347999
8Primary immunodeficiency_Homo sapiens_hsa053402.36797198
9Cell cycle_Homo sapiens_hsa041102.22095076
10Systemic lupus erythematosus_Homo sapiens_hsa053222.03458304
11Nucleotide excision repair_Homo sapiens_hsa034202.02327285
12RNA degradation_Homo sapiens_hsa030181.93432304
13One carbon pool by folate_Homo sapiens_hsa006701.91559054
14Lysine degradation_Homo sapiens_hsa003101.84992720
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.81645672
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.81197576
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.78731190
18Basal transcription factors_Homo sapiens_hsa030221.71202462
19Graft-versus-host disease_Homo sapiens_hsa053321.71093486
20RNA transport_Homo sapiens_hsa030131.70501065
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.58730672
22p53 signaling pathway_Homo sapiens_hsa041151.51258032
23Transcriptional misregulation in cancer_Homo sapiens_hsa052021.42847286
24NF-kappa B signaling pathway_Homo sapiens_hsa040641.39307978
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.33490448
26Ribosome_Homo sapiens_hsa030101.32322579
27Spliceosome_Homo sapiens_hsa030401.30058014
28Pyrimidine metabolism_Homo sapiens_hsa002401.21898959
29Epstein-Barr virus infection_Homo sapiens_hsa051691.16922195
30Alcoholism_Homo sapiens_hsa050341.12974114
31Intestinal immune network for IgA production_Homo sapiens_hsa046721.11787352
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.11554332
33Steroid biosynthesis_Homo sapiens_hsa001001.09904787
34NOD-like receptor signaling pathway_Homo sapiens_hsa046211.08732227
35Allograft rejection_Homo sapiens_hsa053301.05911387
36mRNA surveillance pathway_Homo sapiens_hsa030151.05699108
37Type II diabetes mellitus_Homo sapiens_hsa049301.04231561
38Autoimmune thyroid disease_Homo sapiens_hsa053201.02276852
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00021685
40Base excision repair_Homo sapiens_hsa034100.98723001
41Measles_Homo sapiens_hsa051620.97433787
42Huntingtons disease_Homo sapiens_hsa050160.94532596
43Hematopoietic cell lineage_Homo sapiens_hsa046400.93608948
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.92265992
45RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.90914797
46T cell receptor signaling pathway_Homo sapiens_hsa046600.89433060
47Pancreatic cancer_Homo sapiens_hsa052120.89295717
48Prostate cancer_Homo sapiens_hsa052150.89164591
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.88802010
50Acute myeloid leukemia_Homo sapiens_hsa052210.86429822
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86403362
52Parkinsons disease_Homo sapiens_hsa050120.86196893
53HTLV-I infection_Homo sapiens_hsa051660.84897760
54Jak-STAT signaling pathway_Homo sapiens_hsa046300.83914515
55Oxidative phosphorylation_Homo sapiens_hsa001900.83299820
56Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81025823
57Chronic myeloid leukemia_Homo sapiens_hsa052200.80749739
58Viral carcinogenesis_Homo sapiens_hsa052030.79898707
59Purine metabolism_Homo sapiens_hsa002300.79844993
60Asthma_Homo sapiens_hsa053100.79776255
61Hepatitis B_Homo sapiens_hsa051610.78567529
62Antigen processing and presentation_Homo sapiens_hsa046120.76989406
63Butanoate metabolism_Homo sapiens_hsa006500.75914381
64Olfactory transduction_Homo sapiens_hsa047400.73637468
65TNF signaling pathway_Homo sapiens_hsa046680.70087600
66Proteasome_Homo sapiens_hsa030500.70077782
67MicroRNAs in cancer_Homo sapiens_hsa052060.68832839
68TGF-beta signaling pathway_Homo sapiens_hsa043500.68045666
69Herpes simplex infection_Homo sapiens_hsa051680.65154756
70Protein export_Homo sapiens_hsa030600.63181571
71Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62183830
72FoxO signaling pathway_Homo sapiens_hsa040680.60820795
73Colorectal cancer_Homo sapiens_hsa052100.58272933
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57612537
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55678758
76Melanoma_Homo sapiens_hsa052180.52053847
77Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51323037
78Phototransduction_Homo sapiens_hsa047440.50182951
79Dorso-ventral axis formation_Homo sapiens_hsa043200.48418580
80Alzheimers disease_Homo sapiens_hsa050100.48331087
81Oocyte meiosis_Homo sapiens_hsa041140.44875325
82Renal cell carcinoma_Homo sapiens_hsa052110.41560093
83Type I diabetes mellitus_Homo sapiens_hsa049400.40190452
84Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.38740653
85Viral myocarditis_Homo sapiens_hsa054160.38233503
86Thyroid cancer_Homo sapiens_hsa052160.38066338
87Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35359387
88Pathways in cancer_Homo sapiens_hsa052000.35059862
89Platelet activation_Homo sapiens_hsa046110.34529914
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34132726
91Basal cell carcinoma_Homo sapiens_hsa052170.32614089
92Toll-like receptor signaling pathway_Homo sapiens_hsa046200.32360547
93Taste transduction_Homo sapiens_hsa047420.30991599
94Malaria_Homo sapiens_hsa051440.29107573
95Long-term potentiation_Homo sapiens_hsa047200.28098278
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.26827810
97Longevity regulating pathway - mammal_Homo sapiens_hsa042110.25726581
98Small cell lung cancer_Homo sapiens_hsa052220.25275620
99African trypanosomiasis_Homo sapiens_hsa051430.24996886
100Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.24249959

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