HNRNPA1P70

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.34765997
2negative regulation of T-helper cell differentiation (GO:0045623)4.96914176
3negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)4.96914176
4negative T cell selection (GO:0043383)4.66092176
5regulation of B cell receptor signaling pathway (GO:0050855)4.63441897
6negative thymic T cell selection (GO:0045060)4.60128298
7cytidine deamination (GO:0009972)4.43798852
8cytidine metabolic process (GO:0046087)4.43798852
9cytidine catabolic process (GO:0006216)4.43798852
10positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.28883714
11negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)4.23932684
12positive regulation of gamma-delta T cell activation (GO:0046645)4.23421322
13activated T cell proliferation (GO:0050798)4.07311403
14regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.03990570
15positive thymic T cell selection (GO:0045059)3.97526807
16pyrimidine ribonucleoside catabolic process (GO:0046133)3.96892142
17positive T cell selection (GO:0043368)3.94144291
18cellular response to interleukin-15 (GO:0071350)3.86247723
19positive regulation of granulocyte differentiation (GO:0030854)3.83329520
20regulation of isotype switching to IgG isotypes (GO:0048302)3.80357930
21response to interleukin-15 (GO:0070672)3.78583830
22positive regulation of isotype switching (GO:0045830)3.74463624
23negative regulation of alpha-beta T cell differentiation (GO:0046639)3.66715025
24negative regulation of B cell proliferation (GO:0030889)3.64479529
25regulation of B cell differentiation (GO:0045577)3.57142355
26positive regulation of DNA recombination (GO:0045911)3.54741859
27monocyte chemotaxis (GO:0002548)3.47146220
28T cell migration (GO:0072678)3.46725524
29regulation of chronic inflammatory response (GO:0002676)3.46064407
30positive regulation of B cell differentiation (GO:0045579)3.44358244
31antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.42703509
32positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.35015886
33cellular response to interferon-beta (GO:0035458)3.32383098
34regulation of regulatory T cell differentiation (GO:0045589)3.31264600
35regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.24576762
36regulation of alpha-beta T cell proliferation (GO:0046640)3.22710290
37B cell receptor signaling pathway (GO:0050853)3.20069589
38hepatocyte apoptotic process (GO:0097284)3.18581008
39histone mRNA catabolic process (GO:0071044)3.17239129
40thymic T cell selection (GO:0045061)3.17097917
41positive regulation of alpha-beta T cell proliferation (GO:0046641)3.16836663
42negative regulation of alpha-beta T cell activation (GO:0046636)3.16246889
43mast cell degranulation (GO:0043303)3.14754617
44mast cell activation involved in immune response (GO:0002279)3.14754617
45T cell selection (GO:0045058)3.11241465
46regulation of gamma-delta T cell differentiation (GO:0045586)3.11174024
47positive regulation of immunoglobulin production (GO:0002639)3.10257457
48rRNA catabolic process (GO:0016075)3.07862186
49negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.07207816
50negative regulation of cell killing (GO:0031342)3.07207816
51negative regulation of B cell activation (GO:0050869)2.93086171
52regulation of gamma-delta T cell activation (GO:0046643)2.91770075
53antigen processing and presentation of endogenous antigen (GO:0019883)2.91760022
54DNA catabolic process, exonucleolytic (GO:0000738)2.89640563
55negative regulation of T cell differentiation (GO:0045581)2.87479864
56mast cell activation (GO:0045576)2.86319770
57interferon-gamma secretion (GO:0072643)2.83992479
58positive regulation of immunoglobulin mediated immune response (GO:0002891)2.79337258
59positive regulation of B cell mediated immunity (GO:0002714)2.79337258
60negative regulation of T cell apoptotic process (GO:0070233)2.78139349
61nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.76248637
62CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.75972314
63T-helper cell differentiation (GO:0042093)2.75972314
64exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.75959441
65negative regulation of adaptive immune response (GO:0002820)2.75251882
66regulation of B cell proliferation (GO:0030888)2.74426939
67RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.72786875
68tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.72786875
69negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.72668921
70dendritic cell chemotaxis (GO:0002407)2.71608042
71regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.71396886
72T cell proliferation (GO:0042098)2.70222114
73RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.69841540
74protein complex biogenesis (GO:0070271)2.67390715
75regulation of interleukin-2 biosynthetic process (GO:0045076)2.66915474
76replication fork processing (GO:0031297)2.66586474
77positive regulation of defense response to virus by host (GO:0002230)2.66543302
78antigen receptor-mediated signaling pathway (GO:0050851)2.66263198
79leukocyte aggregation (GO:0070486)2.65264377
80interferon-gamma production (GO:0032609)2.62208821
81mitochondrial respiratory chain complex assembly (GO:0033108)2.61467143
82defense response to protozoan (GO:0042832)2.61285447
83purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.61007753
84regulation of T-helper 1 cell differentiation (GO:0045625)2.60067995
85regulation of T cell receptor signaling pathway (GO:0050856)2.58266258
86negative regulation of T cell mediated immunity (GO:0002710)2.57689691
87dendritic cell migration (GO:0036336)2.56713086
88CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.55382426
89response to interferon-beta (GO:0035456)2.54574809
90mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.53964994
91mitochondrial respiratory chain complex I assembly (GO:0032981)2.53964994
92NADH dehydrogenase complex assembly (GO:0010257)2.53964994
93purine nucleobase biosynthetic process (GO:0009113)2.53878292
94antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.53657474
95alpha-beta T cell activation (GO:0046631)2.51808167
96regulation of isotype switching (GO:0045191)2.51214548
97rRNA modification (GO:0000154)2.50138838
98alpha-beta T cell differentiation involved in immune response (GO:0002293)2.49827295
99alpha-beta T cell activation involved in immune response (GO:0002287)2.49827295
100T cell differentiation involved in immune response (GO:0002292)2.49827295

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.03102952
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.96460439
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.92883122
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.77759454
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.53444692
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.50844032
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.40217786
8ELF1_17652178_ChIP-ChIP_JURKAT_Human3.23885697
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.05451993
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.88298111
11VDR_23849224_ChIP-Seq_CD4+_Human2.79077606
12E2F7_22180533_ChIP-Seq_HELA_Human2.76371766
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.56706992
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.35804814
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.32484151
16FOXP3_21729870_ChIP-Seq_TREG_Human2.30044222
17ELK1_19687146_ChIP-ChIP_HELA_Human2.28815182
18IRF8_21731497_ChIP-ChIP_J774_Mouse2.27513597
19MYB_26560356_Chip-Seq_TH2_Human2.26321203
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.19854688
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16135668
22RUNX_20019798_ChIP-Seq_JUKART_Human2.12412138
23ETS1_20019798_ChIP-Seq_JURKAT_Human2.09964865
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.07250300
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.06736546
26CREB1_15753290_ChIP-ChIP_HEK293T_Human2.00011617
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.98405816
28HOXB4_20404135_ChIP-ChIP_EML_Mouse1.93606068
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.92983499
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91995673
31GATA3_26560356_Chip-Seq_TH2_Human1.78994673
32MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.73000449
33PADI4_21655091_ChIP-ChIP_MCF-7_Human1.71481281
34SPI1_23547873_ChIP-Seq_NB4_Human1.69214386
35MYB_26560356_Chip-Seq_TH1_Human1.68141673
36STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.67447869
37VDR_22108803_ChIP-Seq_LS180_Human1.65773434
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.65379487
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.62803815
40CIITA_25753668_ChIP-Seq_RAJI_Human1.60938496
41GATA3_27048872_Chip-Seq_THYMUS_Human1.57842789
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52404917
43MYC_18555785_ChIP-Seq_MESCs_Mouse1.51301653
44GATA1_22025678_ChIP-Seq_K562_Human1.50662251
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50634591
46STAT4_19710469_ChIP-ChIP_TH1__Mouse1.47530401
47PCGF2_27294783_Chip-Seq_ESCs_Mouse1.47300826
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.45879761
49HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.44869675
50FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.42435880
51RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.39701238
52ZNF274_21170338_ChIP-Seq_K562_Hela1.38105388
53PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34234416
54FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.33361526
55BP1_19119308_ChIP-ChIP_Hs578T_Human1.32402380
56YY1_21170310_ChIP-Seq_MESCs_Mouse1.28135412
57DCP1A_22483619_ChIP-Seq_HELA_Human1.24729668
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21398746
59EWS_26573619_Chip-Seq_HEK293_Human1.19701726
60CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.16914931
61IRF8_27001747_Chip-Seq_BMDM_Mouse1.14361938
62PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11817274
63GABP_19822575_ChIP-Seq_HepG2_Human1.11720475
64ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10755137
65E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06481305
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.05687954
67FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05548874
68NFE2_27457419_Chip-Seq_LIVER_Mouse1.04208279
69TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.03815014
70MYC_18358816_ChIP-ChIP_MESCs_Mouse1.03355007
71SUZ12_27294783_Chip-Seq_NPCs_Mouse1.02008434
72EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.01846045
73MYC_19030024_ChIP-ChIP_MESCs_Mouse1.01236982
74MYC_22102868_ChIP-Seq_BL_Human0.97115972
75FUS_26573619_Chip-Seq_HEK293_Human0.94587222
76ELK1_22589737_ChIP-Seq_MCF10A_Human0.94524108
77EZH2_27294783_Chip-Seq_NPCs_Mouse0.94358095
78CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94150010
79MAF_26560356_Chip-Seq_TH1_Human0.93559632
80GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.93110149
81TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93080105
82POU3F2_20337985_ChIP-ChIP_501MEL_Human0.91569780
83MYC_18940864_ChIP-ChIP_HL60_Human0.90957872
84EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90896322
85GATA3_26560356_Chip-Seq_TH1_Human0.90232870
86NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87699072
87TTF2_22483619_ChIP-Seq_HELA_Human0.87391742
88KDM5A_27292631_Chip-Seq_BREAST_Human0.86734641
89RBPJ_22232070_ChIP-Seq_NCS_Mouse0.86512213
90E2F1_21310950_ChIP-Seq_MCF-7_Human0.85374133
91ERG_20887958_ChIP-Seq_HPC-7_Mouse0.84456176
92SCL_19346495_ChIP-Seq_HPC-7_Human0.84372513
93TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.83168670
94IGF1R_20145208_ChIP-Seq_DFB_Human0.82208408
95RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81523793
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.80638925
97BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.79844785
98LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.79767920
99BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.79299516
100SALL4_22934838_ChIP-ChIP_CD34+_Human0.79276323

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.98166319
2MP0005671_abnormal_response_to3.61400330
3MP0003763_abnormal_thymus_physiology3.22397678
4MP0001986_abnormal_taste_sensitivity3.21388280
5MP0001800_abnormal_humoral_immune2.95779606
6MP0008057_abnormal_DNA_replication2.66368927
7MP0005075_abnormal_melanosome_morpholog2.63057779
8MP0000685_abnormal_immune_system2.50630929
9MP0003436_decreased_susceptibility_to2.33890571
10MP0001790_abnormal_immune_system2.32446857
11MP0005387_immune_system_phenotype2.32446857
12MP0005000_abnormal_immune_tolerance2.28120630
13MP0002723_abnormal_immune_serum2.24765371
14MP0001873_stomach_inflammation2.20349525
15MP0004381_abnormal_hair_follicle2.19760966
16MP0002148_abnormal_hypersensitivity_rea2.14543527
17MP0002420_abnormal_adaptive_immunity2.13971391
18MP0000569_abnormal_digit_pigmentation2.13923999
19MP0002452_abnormal_antigen_presenting2.10272711
20MP0001819_abnormal_immune_cell2.08291144
21MP0005084_abnormal_gallbladder_morpholo2.05276569
22MP0002166_altered_tumor_susceptibility2.05067842
23MP0002398_abnormal_bone_marrow2.03377428
24MP0002396_abnormal_hematopoietic_system2.03201331
25MP0008058_abnormal_DNA_repair2.01092054
26MP0009333_abnormal_splenocyte_physiolog1.92895567
27MP0003786_premature_aging1.87421725
28MP0000689_abnormal_spleen_morphology1.86741275
29MP0002006_tumorigenesis1.85946270
30MP0010094_abnormal_chromosome_stability1.83884472
31MP0000716_abnormal_immune_system1.83460467
32MP0008877_abnormal_DNA_methylation1.81325520
33MP0005310_abnormal_salivary_gland1.81107503
34MP0000703_abnormal_thymus_morphology1.80386599
35MP0009785_altered_susceptibility_to1.80071902
36MP0005025_abnormal_response_to1.76092864
37MP0003724_increased_susceptibility_to1.65193185
38MP0002722_abnormal_immune_system1.61822176
39MP0002405_respiratory_system_inflammati1.61095548
40MP0002429_abnormal_blood_cell1.60939777
41MP0008995_early_reproductive_senescence1.55343951
42MP0006035_abnormal_mitochondrial_morpho1.53957747
43MP0003866_abnormal_defecation1.50601084
44MP0008260_abnormal_autophagy1.46423701
45MP0004957_abnormal_blastocyst_morpholog1.43248872
46MP0002419_abnormal_innate_immunity1.39135642
47MP0001845_abnormal_inflammatory_respons1.30517325
48MP0006082_CNS_inflammation1.26569502
49MP0001853_heart_inflammation1.24421723
50MP0003693_abnormal_embryo_hatching1.17190739
51MP0002019_abnormal_tumor_incidence1.12788502
52MP0003195_calcinosis1.10969231
53MP0003172_abnormal_lysosome_physiology1.10234021
54MP0003646_muscle_fatigue1.08262489
55MP0005174_abnormal_tail_pigmentation1.08144582
56MP0005464_abnormal_platelet_physiology1.07414691
57MP0010155_abnormal_intestine_physiology1.07261735
58MP0000372_irregular_coat_pigmentation1.05882497
59MP0006036_abnormal_mitochondrial_physio1.05678018
60MP0002138_abnormal_hepatobiliary_system1.04420761
61MP0009697_abnormal_copulation1.03251073
62MP0003111_abnormal_nucleus_morphology1.01388142
63MP0008872_abnormal_physiological_respon1.01350608
64MP0002095_abnormal_skin_pigmentation1.00363478
65MP0003567_abnormal_fetal_cardiomyocyte0.97425623
66MP0010307_abnormal_tumor_latency0.97087930
67MP0002277_abnormal_respiratory_mucosa0.95348786
68MP0004084_abnormal_cardiac_muscle0.93661902
69MP0003252_abnormal_bile_duct0.91662979
70MP0002009_preneoplasia0.90588383
71MP0003077_abnormal_cell_cycle0.90369638
72MP0008469_abnormal_protein_level0.89659486
73MP0003718_maternal_effect0.88898129
74MP0003186_abnormal_redox_activity0.87942735
75MP0005408_hypopigmentation0.87639064
76MP0009764_decreased_sensitivity_to0.85155435
77MP0004883_abnormal_blood_vessel0.81412380
78MP0001663_abnormal_digestive_system0.80860302
79MP0002102_abnormal_ear_morphology0.80223833
80MP0005377_hearing/vestibular/ear_phenot0.80191451
81MP0003878_abnormal_ear_physiology0.80191451
82MP0000015_abnormal_ear_pigmentation0.79799641
83MP0002693_abnormal_pancreas_physiology0.77469163
84MP0002933_joint_inflammation0.76013129
85MP0000465_gastrointestinal_hemorrhage0.74114713
86MP0001919_abnormal_reproductive_system0.73494200
87MP0001764_abnormal_homeostasis0.73154686
88MP0003806_abnormal_nucleotide_metabolis0.72825598
89MP0003045_fibrosis0.72371345
90MP0004145_abnormal_muscle_electrophysio0.72054123
91MP0008875_abnormal_xenobiotic_pharmacok0.71623167
92MP0000313_abnormal_cell_death0.69300134
93MP0003303_peritoneal_inflammation0.69180112
94MP0005083_abnormal_biliary_tract0.68189492
95MP0008007_abnormal_cellular_replicative0.67228846
96MP0008873_increased_physiological_sensi0.64991135
97MP0004484_altered_response_of0.64415155
98MP0005167_abnormal_blood-brain_barrier0.64245714
99MP0003221_abnormal_cardiomyocyte_apopto0.62804930
100MP0005085_abnormal_gallbladder_physiolo0.62774587

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)5.07099282
2Abnormality of T cell number (HP:0011839)4.70188834
3IgG deficiency (HP:0004315)4.16072824
4Panhypogammaglobulinemia (HP:0003139)4.15718704
5Abnormality of T cells (HP:0002843)4.13603163
6Severe combined immunodeficiency (HP:0004430)3.82239597
7Agammaglobulinemia (HP:0004432)3.76399269
8Abnormal delayed hypersensitivity skin test (HP:0002963)3.65896415
9IgM deficiency (HP:0002850)3.60860801
10Elevated erythrocyte sedimentation rate (HP:0003565)3.52653247
11Encephalitis (HP:0002383)3.36097380
12Recurrent cutaneous fungal infections (HP:0011370)3.36006961
13Chronic mucocutaneous candidiasis (HP:0002728)3.36006961
14Stomatitis (HP:0010280)3.28251166
15Recurrent viral infections (HP:0004429)3.23218137
16Recurrent bronchitis (HP:0002837)3.18514101
17Thyroiditis (HP:0100646)3.13897451
18Recurrent fungal infections (HP:0002841)3.09334310
19Combined immunodeficiency (HP:0005387)3.06635265
20Recurrent bacterial skin infections (HP:0005406)3.05492858
21Abnormality of T cell physiology (HP:0011840)3.01987112
22Hypoplasia of the thymus (HP:0000778)2.97896926
233-Methylglutaconic aciduria (HP:0003535)2.89289236
24Abnormal mitochondria in muscle tissue (HP:0008316)2.77819539
25Meningitis (HP:0001287)2.75980481
26Aplastic anemia (HP:0001915)2.74860271
27Microvesicular hepatic steatosis (HP:0001414)2.73229399
28Abnormality of the prostate (HP:0008775)2.64726021
29Abnormality of eosinophils (HP:0001879)2.60758993
30Acute necrotizing encephalopathy (HP:0006965)2.60079583
31Pustule (HP:0200039)2.52511885
32Mitochondrial inheritance (HP:0001427)2.52090772
33Recurrent abscess formation (HP:0002722)2.51217732
34Recurrent skin infections (HP:0001581)2.48828116
35Abnormality of B cell number (HP:0010975)2.46596122
36Lymphopenia (HP:0001888)2.44268962
37Hypoproteinemia (HP:0003075)2.42336205
38Hepatocellular necrosis (HP:0001404)2.41593869
39Leukocytosis (HP:0001974)2.38356162
40Decreased activity of mitochondrial respiratory chain (HP:0008972)2.36507999
41Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.36507999
42Methylmalonic aciduria (HP:0012120)2.36146314
43Cellular immunodeficiency (HP:0005374)2.35426643
44Increased CSF lactate (HP:0002490)2.35135785
45Abnormality of chromosome stability (HP:0003220)2.31008771
46Myositis (HP:0100614)2.30764030
47Lymphoma (HP:0002665)2.27479475
48Progressive macrocephaly (HP:0004481)2.26249479
49Abnormality of cells of the lymphoid lineage (HP:0012140)2.24452089
50Acute encephalopathy (HP:0006846)2.22740819
51Autoimmune hemolytic anemia (HP:0001890)2.21110086
52Eosinophilia (HP:0001880)2.20176099
53Methylmalonic acidemia (HP:0002912)2.20096285
54Chronic otitis media (HP:0000389)2.18970920
55Retrobulbar optic neuritis (HP:0100654)2.16662148
56Optic neuritis (HP:0100653)2.16662148
57Increased IgM level (HP:0003496)2.15289014
58IgA deficiency (HP:0002720)2.14219586
59Pancreatic cysts (HP:0001737)2.12928079
60Hepatic necrosis (HP:0002605)2.11824527
61Pancytopenia (HP:0001876)2.11453328
62Bronchitis (HP:0012387)2.11283461
63Chronic diarrhea (HP:0002028)2.07636941
64Oral leukoplakia (HP:0002745)2.05602634
65Eczematoid dermatitis (HP:0000976)2.05492980
66Carpal bone hypoplasia (HP:0001498)2.05290727
67Vasculitis (HP:0002633)2.05209409
68Abnormality of the preputium (HP:0100587)2.05114924
69Alveolar cell carcinoma (HP:0006519)2.01842131
70Granulocytopenia (HP:0001913)1.98890385
71Increased serum lactate (HP:0002151)1.98888331
72Mediastinal lymphadenopathy (HP:0100721)1.98646380
73Clubbing of toes (HP:0100760)1.96884537
74Aplasia/Hypoplasia of the uvula (HP:0010293)1.93676461
75Acute hepatic failure (HP:0006554)1.93473057
76Abnormality of midbrain morphology (HP:0002418)1.93271117
77Molar tooth sign on MRI (HP:0002419)1.93271117
78Recurrent sinusitis (HP:0011108)1.92687994
79Basal cell carcinoma (HP:0002671)1.92551733
80Neoplasm of the tracheobronchial system (HP:0100552)1.92374417
81Absent rod-and cone-mediated responses on ERG (HP:0007688)1.91124011
82B lymphocytopenia (HP:0010976)1.90918610
83Cerebral edema (HP:0002181)1.88754416
84Stomach cancer (HP:0012126)1.87210092
85Pulmonary infiltrates (HP:0002113)1.86304387
86Meckel diverticulum (HP:0002245)1.84497745
87Pancreatic fibrosis (HP:0100732)1.84080767
88Increased intramyocellular lipid droplets (HP:0012240)1.83752683
89Dicarboxylic aciduria (HP:0003215)1.81954911
90Abnormality of dicarboxylic acid metabolism (HP:0010995)1.81954911
91Leukopenia (HP:0001882)1.81315373
92Abnormal albumin level (HP:0012116)1.80961256
93Hypoalbuminemia (HP:0003073)1.80961256
94Abnormality of the ileum (HP:0001549)1.80381938
95Chronic hepatic failure (HP:0100626)1.79791864
96Progressive microcephaly (HP:0000253)1.79558906
97Chronic sinusitis (HP:0011109)1.79265787
98Colon cancer (HP:0003003)1.77412905
99True hermaphroditism (HP:0010459)1.74819347
100Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.73563688

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.93433388
2TAOK33.82540728
3EIF2AK33.23884073
4MAP4K12.85451781
5TSSK62.59186556
6EIF2AK12.51577296
7FES2.31912335
8PIK3CG2.19104209
9IKBKE2.07766592
10VRK22.03555198
11MST41.96323755
12NUAK11.89764946
13NEK11.89321449
14PASK1.73053063
15JAK31.71707315
16TEC1.70496149
17TLK11.70029768
18MAP3K141.68797063
19ITK1.63909543
20RIPK41.60046586
21SYK1.59512873
22MKNK11.52608188
23GRK61.48928196
24TNK21.47257866
25TIE11.45992076
26CCNB11.44160504
27IKBKB1.43398764
28STK161.42933553
29VRK11.38284770
30IRAK41.38080779
31PBK1.37921611
32BCKDK1.35439711
33BTK1.34290491
34SRPK11.28524589
35ADRBK21.23493470
36PLK31.22853961
37TYK21.21701631
38BLK1.21014974
39ACVR1B1.20558855
40BUB11.19946209
41CSK1.18581552
42LCK1.17453314
43PRKCQ1.17293243
44TAF11.16907367
45ZAK1.16300368
46FRK1.13551921
47LYN1.05853945
48MAP4K21.01859740
49ZAP701.00830970
50FGR1.00256223
51DAPK10.98770601
52IRAK10.96849538
53NLK0.96609728
54STK40.96581082
55KIT0.96142286
56PIM10.92886748
57ATR0.92155981
58TGFBR10.88822251
59BMPR1B0.88799618
60PLK20.82124023
61FLT30.79544441
62TBK10.76755123
63JAK10.72379696
64GRK10.68196370
65CDC70.67504326
66MAPKAPK30.66895133
67CSF1R0.66463093
68EIF2AK20.65574362
69CDK40.65312727
70PLK40.65043994
71CHUK0.63020141
72PTK2B0.61721544
73CAMKK20.61581679
74HCK0.59791990
75SGK20.53867829
76FGFR30.53250500
77MKNK20.52294076
78MAP3K130.52191670
79JAK20.44975282
80KDR0.44708911
81GRK50.42569317
82RPS6KA50.42205023
83TNIK0.42162185
84MAP2K60.41425355
85MATK0.40534240
86ALK0.38594061
87MARK30.38398125
88STK100.37913875
89OBSCN0.36328909
90INSRR0.35652411
91YES10.33894288
92MAP2K30.33887369
93DYRK20.33868695
94BRD40.32888049
95IRAK20.29385803
96CSNK2A10.28917475
97AKT30.28304883
98NEK90.28241922
99DYRK30.28076196
100WNK30.27660010

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.01959421
2Autoimmune thyroid disease_Homo sapiens_hsa053203.57275107
3Allograft rejection_Homo sapiens_hsa053303.46092962
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.29950857
5Proteasome_Homo sapiens_hsa030503.28184974
6Asthma_Homo sapiens_hsa053102.73262393
7Graft-versus-host disease_Homo sapiens_hsa053322.72669315
8Homologous recombination_Homo sapiens_hsa034402.63500164
9Antigen processing and presentation_Homo sapiens_hsa046122.47584473
10Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.38431134
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.33736592
12Type I diabetes mellitus_Homo sapiens_hsa049402.20680297
13Mismatch repair_Homo sapiens_hsa034302.11716793
14Non-homologous end-joining_Homo sapiens_hsa034502.05428753
15RNA polymerase_Homo sapiens_hsa030202.03484102
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.00612396
17Ribosome_Homo sapiens_hsa030101.97702253
18RNA degradation_Homo sapiens_hsa030181.89267958
19DNA replication_Homo sapiens_hsa030301.83999997
20T cell receptor signaling pathway_Homo sapiens_hsa046601.78082216
21Measles_Homo sapiens_hsa051621.75215255
22Hematopoietic cell lineage_Homo sapiens_hsa046401.64859543
23Protein export_Homo sapiens_hsa030601.63439525
24Fanconi anemia pathway_Homo sapiens_hsa034601.63134895
25Leishmaniasis_Homo sapiens_hsa051401.62825931
26Parkinsons disease_Homo sapiens_hsa050121.58609647
27Spliceosome_Homo sapiens_hsa030401.58298107
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.49205783
29Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.48087610
30NF-kappa B signaling pathway_Homo sapiens_hsa040641.47812425
31Oxidative phosphorylation_Homo sapiens_hsa001901.41918948
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.31501865
33RNA transport_Homo sapiens_hsa030131.25678093
34Basal transcription factors_Homo sapiens_hsa030221.25437601
35Viral myocarditis_Homo sapiens_hsa054161.22408799
36Epstein-Barr virus infection_Homo sapiens_hsa051691.20406943
37Herpes simplex infection_Homo sapiens_hsa051681.15126812
38Propanoate metabolism_Homo sapiens_hsa006401.09533711
39One carbon pool by folate_Homo sapiens_hsa006701.08687207
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.05827606
41B cell receptor signaling pathway_Homo sapiens_hsa046621.05236290
42Rheumatoid arthritis_Homo sapiens_hsa053231.04912812
43RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.99327043
44Staphylococcus aureus infection_Homo sapiens_hsa051500.97818141
45Nucleotide excision repair_Homo sapiens_hsa034200.95547112
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94384220
47Pyrimidine metabolism_Homo sapiens_hsa002400.92589082
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.92560221
49Jak-STAT signaling pathway_Homo sapiens_hsa046300.90629636
50Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88310273
51Purine metabolism_Homo sapiens_hsa002300.85034004
52Huntingtons disease_Homo sapiens_hsa050160.78411825
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.78137618
54Chemokine signaling pathway_Homo sapiens_hsa040620.75756935
55Influenza A_Homo sapiens_hsa051640.75118575
56Phototransduction_Homo sapiens_hsa047440.74379401
57Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.70991399
58Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69565049
59Regulation of autophagy_Homo sapiens_hsa041400.69119491
60Caffeine metabolism_Homo sapiens_hsa002320.65625110
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.63502110
62Alzheimers disease_Homo sapiens_hsa050100.59439677
63Legionellosis_Homo sapiens_hsa051340.59291092
64Base excision repair_Homo sapiens_hsa034100.58551857
65Apoptosis_Homo sapiens_hsa042100.57091313
66Osteoclast differentiation_Homo sapiens_hsa043800.53488973
67Tuberculosis_Homo sapiens_hsa051520.53226194
68Peroxisome_Homo sapiens_hsa041460.49268824
69HTLV-I infection_Homo sapiens_hsa051660.48603375
70Toxoplasmosis_Homo sapiens_hsa051450.48321652
71Cell cycle_Homo sapiens_hsa041100.45484403
72Linoleic acid metabolism_Homo sapiens_hsa005910.42777345
732-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41767050
74Toll-like receptor signaling pathway_Homo sapiens_hsa046200.40744938
75Systemic lupus erythematosus_Homo sapiens_hsa053220.37459242
76Butanoate metabolism_Homo sapiens_hsa006500.36893352
77Sulfur metabolism_Homo sapiens_hsa009200.35583017
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33918057
79mRNA surveillance pathway_Homo sapiens_hsa030150.33842523
80Hepatitis B_Homo sapiens_hsa051610.33445244
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32193940
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.31916705
83Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.31790165
84Tryptophan metabolism_Homo sapiens_hsa003800.30456705
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29939041
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29208893
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29122991
88Shigellosis_Homo sapiens_hsa051310.28418481
89Nitrogen metabolism_Homo sapiens_hsa009100.28228432
90p53 signaling pathway_Homo sapiens_hsa041150.26657018
91Glycerolipid metabolism_Homo sapiens_hsa005610.23446362
92Viral carcinogenesis_Homo sapiens_hsa052030.23013701
93Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.21998113
94Platelet activation_Homo sapiens_hsa046110.21032661
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.19272312
96TNF signaling pathway_Homo sapiens_hsa046680.17183562
97Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.16670943
98Metabolic pathways_Homo sapiens_hsa011000.15167710
99Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.13478426
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.13463253

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »