GTF3C1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)4.14658896
2DNA unwinding involved in DNA replication (GO:0006268)3.94521253
3peptidyl-lysine dimethylation (GO:0018027)3.93009662
4retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.74253071
5cytoskeletal anchoring at plasma membrane (GO:0007016)3.73611816
6regulation of mammary gland epithelial cell proliferation (GO:0033599)3.57072951
7pore complex assembly (GO:0046931)3.39847455
8mitotic chromosome condensation (GO:0007076)3.36858148
9protein retention in ER lumen (GO:0006621)3.31535853
10protein complex localization (GO:0031503)3.29237899
11nuclear pore complex assembly (GO:0051292)3.28208265
12embryonic foregut morphogenesis (GO:0048617)3.25941014
13maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.24909572
14insulin-like growth factor receptor signaling pathway (GO:0048009)3.22248602
15establishment of nucleus localization (GO:0040023)3.20837631
16basement membrane organization (GO:0071711)3.18463112
17cellular protein complex localization (GO:0034629)3.18208898
18negative regulation of cell size (GO:0045792)3.16928525
19NLS-bearing protein import into nucleus (GO:0006607)3.15488018
20stress granule assembly (GO:0034063)3.13735881
21regulation of hippo signaling (GO:0035330)3.11434967
22regulation of NFAT protein import into nucleus (GO:0051532)3.10916971
23hemidesmosome assembly (GO:0031581)3.08991850
24adherens junction assembly (GO:0034333)3.08712963
25proline biosynthetic process (GO:0006561)3.08186096
26nuclear pore organization (GO:0006999)3.04851185
27heterochromatin organization (GO:0070828)3.02096972
28polarized epithelial cell differentiation (GO:0030859)3.01171032
29glial cell proliferation (GO:0014009)2.97110463
30protein localization to endosome (GO:0036010)2.96607968
31desmosome organization (GO:0002934)2.95760446
32cytoplasmic mRNA processing body assembly (GO:0033962)2.95317129
33glucocorticoid receptor signaling pathway (GO:0042921)2.94263163
34sodium ion export (GO:0071436)2.92196010
35layer formation in cerebral cortex (GO:0021819)2.92035057
36cell communication by electrical coupling (GO:0010644)2.89637580
37cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.89097609
38regulation of translational fidelity (GO:0006450)2.88253050
39convergent extension (GO:0060026)2.87855912
40activation of Rac GTPase activity (GO:0032863)2.85382687
41hippo signaling (GO:0035329)2.84449421
42semaphorin-plexin signaling pathway (GO:0071526)2.84318278
43peptidyl-arginine omega-N-methylation (GO:0035247)2.82205469
44regulation of glucose import in response to insulin stimulus (GO:2001273)2.81565191
45paraxial mesoderm development (GO:0048339)2.81514440
46regulation of histone H3-K27 methylation (GO:0061085)2.80526078
47regulation of translational termination (GO:0006449)2.79874902
48establishment of apical/basal cell polarity (GO:0035089)2.76626994
49plasma membrane repair (GO:0001778)2.76054426
50apoptotic process involved in morphogenesis (GO:0060561)2.75531428
51focal adhesion assembly (GO:0048041)2.74844510
52cell-substrate adherens junction assembly (GO:0007045)2.74844510
53positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.74814863
54positive regulation of histone deacetylation (GO:0031065)2.74684015
55negative regulation of histone methylation (GO:0031061)2.71449917
56histone H3-K9 demethylation (GO:0033169)2.69812422
57establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.68207496
58maternal placenta development (GO:0001893)2.65743771
59planar cell polarity pathway involved in neural tube closure (GO:0090179)2.63841769
60mitotic sister chromatid cohesion (GO:0007064)2.59847031
61gastrulation with mouth forming second (GO:0001702)2.58777133
62DNA duplex unwinding (GO:0032508)2.58744088
63protein export from nucleus (GO:0006611)2.58588714
64Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.58393524
65regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.56111822
66negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.52049419
67embryonic eye morphogenesis (GO:0048048)2.50576524
68negative regulation of potassium ion transmembrane transport (GO:1901380)2.49679951
69regulation of cardioblast differentiation (GO:0051890)2.49325015
70dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.49323373
71embryonic process involved in female pregnancy (GO:0060136)2.48781908
72vesicle coating (GO:0006901)2.48689368
73cardiac myofibril assembly (GO:0055003)2.47216258
74locomotory exploration behavior (GO:0035641)2.46578014
75regulation of establishment of planar polarity (GO:0090175)2.46365628
76cell-substrate junction assembly (GO:0007044)2.46154809
77regulation of RNA export from nucleus (GO:0046831)2.46009605
78dosage compensation (GO:0007549)2.43910587
79positive regulation of nuclease activity (GO:0032075)2.43740418
80spliceosomal tri-snRNP complex assembly (GO:0000244)2.42425137
81dorsal/ventral axis specification (GO:0009950)2.41436802
82gene silencing (GO:0016458)2.41419889
83neural tube development (GO:0021915)2.41077365
84establishment of monopolar cell polarity (GO:0061162)2.40304617
85establishment or maintenance of monopolar cell polarity (GO:0061339)2.40304617
86regulation of early endosome to late endosome transport (GO:2000641)2.40181678
87negative regulation of organelle assembly (GO:1902116)2.39977716
88chromatin assembly (GO:0031497)2.39972746
89regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.39762655
90regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.39747248
91positive regulation of RNA splicing (GO:0033120)2.38910368
92synaptic vesicle maturation (GO:0016188)2.38779306
93branching involved in mammary gland duct morphogenesis (GO:0060444)2.38356443
94eye morphogenesis (GO:0048592)2.37585499
95intracellular estrogen receptor signaling pathway (GO:0030520)2.37548725
96negative regulation of cytosolic calcium ion concentration (GO:0051481)2.37234604
97histone arginine methylation (GO:0034969)2.37181670
98stress fiber assembly (GO:0043149)2.37070797
99protein localization to microtubule (GO:0035372)2.36657673
100gene silencing by RNA (GO:0031047)2.35448398
101positive regulation of synapse maturation (GO:0090129)2.34257932
102DNA geometric change (GO:0032392)2.33760724
103peptidyl-arginine N-methylation (GO:0035246)2.33092810
104peptidyl-arginine methylation (GO:0018216)2.33092810
105epithelial cell differentiation involved in prostate gland development (GO:0060742)2.32495276
106nucleus localization (GO:0051647)2.32471621
107corticosteroid receptor signaling pathway (GO:0031958)2.32313106
108embryonic camera-type eye morphogenesis (GO:0048596)2.30982088
109notochord development (GO:0030903)2.30319438
110negative regulation of vascular permeability (GO:0043116)2.29919472
111regulation of short-term neuronal synaptic plasticity (GO:0048172)2.28835712
112histone H3-K36 demethylation (GO:0070544)2.28721426
113regulation of sister chromatid cohesion (GO:0007063)2.27596865
114heart morphogenesis (GO:0003007)2.27472170
115negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.27391635
116positive regulation of blood vessel endothelial cell migration (GO:0043536)2.27233798
117regulation of fatty acid beta-oxidation (GO:0031998)2.26966542
118establishment or maintenance of bipolar cell polarity (GO:0061245)2.26897088
119establishment or maintenance of apical/basal cell polarity (GO:0035088)2.26897088
120Golgi transport vesicle coating (GO:0048200)2.26342965
121COPI coating of Golgi vesicle (GO:0048205)2.26342965
122skin morphogenesis (GO:0043589)2.26330613
123positive regulation of glycogen biosynthetic process (GO:0045725)2.24774046
124adherens junction organization (GO:0034332)2.24027661
125COPII vesicle coating (GO:0048208)2.23801576
126response to epidermal growth factor (GO:0070849)2.23669891
127morphogenesis of an epithelial sheet (GO:0002011)2.23410012
128mRNA stabilization (GO:0048255)2.23336450
129RNA stabilization (GO:0043489)2.23336450
130cellular response to epidermal growth factor stimulus (GO:0071364)2.23208705
131chromosome condensation (GO:0030261)2.22972386
132gap junction assembly (GO:0016264)2.22880066
133regulation of chromatin binding (GO:0035561)2.22331901
134macroautophagy (GO:0016236)2.22234097
135protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.21882111
136endoplasmic reticulum unfolded protein response (GO:0030968)2.21830097
137regulation of mitotic spindle organization (GO:0060236)2.21400388
138synaptic vesicle docking involved in exocytosis (GO:0016081)2.21333701
139response to UV-C (GO:0010225)2.21107679
140cell communication involved in cardiac conduction (GO:0086065)2.20779787
141positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.20726010
142histone H4-K16 acetylation (GO:0043984)2.20664488
143nucleosome disassembly (GO:0006337)2.20542425
144protein-DNA complex disassembly (GO:0032986)2.20542425
145histone lysine demethylation (GO:0070076)2.19052970
146histone H4-K5 acetylation (GO:0043981)2.18139105
147histone H4-K8 acetylation (GO:0043982)2.18139105
148activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.17936103
149positive regulation of SMAD protein import into nucleus (GO:0060391)2.16767786
150negative regulation of fatty acid transport (GO:2000192)2.16582405
151collecting duct development (GO:0072044)2.16364526
152chromatin silencing (GO:0006342)2.16109279
153epithelial cell-cell adhesion (GO:0090136)2.16038087
154histone H2A monoubiquitination (GO:0035518)2.14311412
155regulation of clathrin-mediated endocytosis (GO:2000369)2.14215863
156regulation of nucleobase-containing compound transport (GO:0032239)2.12486326
157regulation of tight junction assembly (GO:2000810)2.11682151

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.47017866
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.10087762
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.03502187
4E2F7_22180533_ChIP-Seq_HELA_Human2.95793171
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.76264709
6MYC_22102868_ChIP-Seq_BL_Human2.53351360
7* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.47817296
8SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.38414970
9* DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.35066828
10KDM2B_26808549_Chip-Seq_DND41_Human2.34952639
11ZFP281_27345836_Chip-Seq_ESCs_Mouse2.32910360
12ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.24070367
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.19568715
14KDM2B_26808549_Chip-Seq_SUP-B15_Human2.14401902
15WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.12063371
16STAT6_21828071_ChIP-Seq_BEAS2B_Human2.09696321
17KDM2B_26808549_Chip-Seq_K562_Human2.02773461
18KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.96811053
19KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.94817530
20TCF7_22412390_ChIP-Seq_EML_Mouse1.94648071
21SALL1_21062744_ChIP-ChIP_HESCs_Human1.94180588
22TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.91793834
23EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.90786417
24AR_21909140_ChIP-Seq_LNCAP_Human1.86695321
25STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.85806193
26ZNF263_19887448_ChIP-Seq_K562_Human1.83869571
27EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.80992499
28KDM2B_26808549_Chip-Seq_JURKAT_Human1.80456865
29* RARB_27405468_Chip-Seq_BRAIN_Mouse1.80022138
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.74211130
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.72731959
32SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.72112660
33P300_27058665_Chip-Seq_ZR-75-30cells_Human1.71306958
34DROSHA_22980978_ChIP-Seq_HELA_Human1.69292894
35ESR1_15608294_ChIP-ChIP_MCF-7_Human1.69157071
36EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.69091609
37THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.68179926
38* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.66052240
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.65828975
40DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.65367579
41TP63_17297297_ChIP-ChIP_HaCaT_Human1.64952132
42ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.63773150
43CLOCK_20551151_ChIP-Seq_293T_Human1.61665798
44* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.58422814
45MYC_18555785_ChIP-Seq_MESCs_Mouse1.58042943
46ZFX_18555785_ChIP-Seq_MESCs_Mouse1.55578544
47KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.52771267
48KLF4_18555785_ChIP-Seq_MESCs_Mouse1.49497061
49FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.49135610
50TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.48375249
51CREB1_26743006_Chip-Seq_LNCaP_Human1.47943225
52LXR_22292898_ChIP-Seq_THP-1_Human1.47532207
53* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.46112689
54ELK3_25401928_ChIP-Seq_HUVEC_Human1.42747496
55ISL1_27105846_Chip-Seq_CPCs_Mouse1.41745356
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.37537719
57NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.33695332
58RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.33259180
59RACK7_27058665_Chip-Seq_MCF-7_Human1.32912368
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32674189
61RUNX1_27514584_Chip-Seq_MCF-7_Human1.31933718
62ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.31920932
63TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30631884
64MYC_19079543_ChIP-ChIP_MESCs_Mouse1.30305557
65SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.29385597
66GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28446130
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.26194269
68CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.25142888
69BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.20522074
70KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.20509805
71WT1_25993318_ChIP-Seq_PODOCYTE_Human1.19888425
72* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.19767952
73* TBX20_22080862_ChIP-Seq_HEART_Mouse1.18464773
74* TBX20_22328084_ChIP-Seq_HEART_Mouse1.18464773
75FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.18377234
76FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.18006606
77UBF1/2_26484160_Chip-Seq_HMECs_Human1.17067678
78ESR2_21235772_ChIP-Seq_MCF-7_Human1.16499818
79TP53_22127205_ChIP-Seq_IMR90_Human1.16294592
80TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.16284398
81ATF3_27146783_Chip-Seq_COLON_Human1.15703631
82* TP53_23651856_ChIP-Seq_MEFs_Mouse1.15525129
83XRN2_22483619_ChIP-Seq_HELA_Human1.15031571
84FOXA2_19822575_ChIP-Seq_HepG2_Human1.14890490
85POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.13881958
86RARG_19884340_ChIP-ChIP_MEFs_Mouse1.13515211
87* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.12409554
88PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.11778403
89HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.11428070
90NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.11282624
91NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.10742994
92SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.10392449
93NFIB_24661679_ChIP-Seq_LUNG_Mouse1.10336516
94NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.09435134
95FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09028409
96MYCN_18555785_ChIP-Seq_MESCs_Mouse1.08280992
97POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.07697349
98TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.07670573
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.07115400
100SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.06375211
101DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06322467
102NANOG_18555785_ChIP-Seq_MESCs_Mouse1.06178484
103* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.06018750
104PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.05228457
105* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.05187219
106TET1_21451524_ChIP-Seq_MESCs_Mouse1.05067610
107ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.04510582
108CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.04311085
109CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04253688
110VDR_21846776_ChIP-Seq_THP-1_Human1.04018299
111CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03984465
112MYC_19030024_ChIP-ChIP_MESCs_Mouse1.02790464
113CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.02764627
114NCOR1_26117541_ChIP-Seq_K562_Human1.02693205
115UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.01544324
116E2F1_21310950_ChIP-Seq_MCF-7_Human1.01139559
117* AR_19668381_ChIP-Seq_PC3_Human1.01107023
118P68_20966046_ChIP-Seq_HELA_Human0.99739042
119HIF1A_21447827_ChIP-Seq_MCF-7_Human0.99225749
120CTNNB1_20460455_ChIP-Seq_HCT116_Human0.98809714
121STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98236520
122DNAJC2_21179169_ChIP-ChIP_NT2_Human0.96746207
123ESR1_20079471_ChIP-ChIP_T-47D_Human0.95996923
124NANOG_21062744_ChIP-ChIP_HESCs_Human0.95754548
125FOXO3_23340844_ChIP-Seq_DLD1_Human0.94733286
126SMC4_20622854_ChIP-Seq_HELA_Human0.93149283
127POU5F1_16518401_ChIP-PET_MESCs_Mouse0.92599965
128EP300_21415370_ChIP-Seq_HL-1_Mouse0.92510261
129RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.91937384
130PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91862450
131SOX9_24532713_ChIP-Seq_HFSC_Mouse0.90249042
132CHD1_26751641_Chip-Seq_LNCaP_Human0.90204881
133ERG_21242973_ChIP-ChIP_JURKAT_Human0.89999919
134ZNF217_24962896_ChIP-Seq_MCF-7_Human0.89485810
135EZH2_22144423_ChIP-Seq_EOC_Human0.89179099
136TBX3_20139965_ChIP-Seq_ESCs_Mouse0.89039844
137ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.88305251
138TBX3_20139965_ChIP-Seq_MESCs_Mouse0.88254043
139RBPJ_22232070_ChIP-Seq_NCS_Mouse0.88237508

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.76409262
2MP0003283_abnormal_digestive_organ3.05156514
3MP0005076_abnormal_cell_differentiation2.69786529
4MP0010352_gastrointestinal_tract_polyps2.66259969
5MP0000569_abnormal_digit_pigmentation2.55778867
6MP0010234_abnormal_vibrissa_follicle2.50726738
7MP0004859_abnormal_synaptic_plasticity2.40114263
8MP0005623_abnormal_meninges_morphology2.32536178
9MP0000537_abnormal_urethra_morphology2.32459047
10MP0008961_abnormal_basal_metabolism2.23513738
11MP0004233_abnormal_muscle_weight2.06647593
12MP0005409_darkened_coat_color1.99786820
13MP0009780_abnormal_chondrocyte_physiolo1.96699465
14MP0004084_abnormal_cardiac_muscle1.95283729
15MP0005451_abnormal_body_composition1.91245235
16MP0001849_ear_inflammation1.89842730
17MP0003115_abnormal_respiratory_system1.85376296
18MP0010307_abnormal_tumor_latency1.73713118
19MP0002234_abnormal_pharynx_morphology1.71692452
20MP0003119_abnormal_digestive_system1.68058482
21MP0003123_paternal_imprinting1.67379673
22MP0002084_abnormal_developmental_patter1.65387012
23MP0000579_abnormal_nail_morphology1.64973010
24MP0003121_genomic_imprinting1.64577236
25MP0005257_abnormal_intraocular_pressure1.64569897
26MP0002653_abnormal_ependyma_morphology1.63864956
27MP0002796_impaired_skin_barrier1.62752565
28MP0000733_abnormal_muscle_development1.62686892
29MP0002009_preneoplasia1.62549802
30MP0009053_abnormal_anal_canal1.61272017
31MP0003122_maternal_imprinting1.60655118
32MP0004197_abnormal_fetal_growth/weight/1.59980293
33MP0004858_abnormal_nervous_system1.59974899
34MP0003941_abnormal_skin_development1.59486804
35MP0003300_gastrointestinal_ulcer1.56636904
36MP0003787_abnormal_imprinting1.55861407
37MP0001730_embryonic_growth_arrest1.54844782
38MP0003890_abnormal_embryonic-extraembry1.54844758
39MP0000428_abnormal_craniofacial_morphol1.54475003
40MP0002909_abnormal_adrenal_gland1.51000681
41MP0002249_abnormal_larynx_morphology1.48739453
42MP0003566_abnormal_cell_adhesion1.44132465
43MP0003045_fibrosis1.44011936
44MP0004272_abnormal_basement_membrane1.41893380
45MP0000534_abnormal_ureter_morphology1.41248524
46MP0002877_abnormal_melanocyte_morpholog1.40878477
47MP0005380_embryogenesis_phenotype1.39726181
48MP0001672_abnormal_embryogenesis/_devel1.39726181
49MP0005187_abnormal_penis_morphology1.39343116
50MP0003984_embryonic_growth_retardation1.38735291
51MP0002088_abnormal_embryonic_growth/wei1.38540753
52MP0010030_abnormal_orbit_morphology1.37819724
53MP0003453_abnormal_keratinocyte_physiol1.37670159
54MP0004957_abnormal_blastocyst_morpholog1.36718880
55MP0000751_myopathy1.36458290
56MP0000566_synostosis1.34469746
57MP0002060_abnormal_skin_morphology1.33558567
58MP0002086_abnormal_extraembryonic_tissu1.33071209
59MP0003935_abnormal_craniofacial_develop1.31889990
60MP0009672_abnormal_birth_weight1.31073170
61MP0008260_abnormal_autophagy1.30389616
62MP0002085_abnormal_embryonic_tissue1.30196020
63MP0010630_abnormal_cardiac_muscle1.29431869
64MP0003077_abnormal_cell_cycle1.28474269
65MP0004087_abnormal_muscle_fiber1.27370263
66MP0008932_abnormal_embryonic_tissue1.24872475
67MP0005275_abnormal_skin_tensile1.23785411
68MP0003693_abnormal_embryo_hatching1.23469308
69MP0000003_abnormal_adipose_tissue1.23421022
70MP0003091_abnormal_cell_migration1.23294736
71MP0005501_abnormal_skin_physiology1.22245039
72MP0009703_decreased_birth_body1.21939269
73MP0001661_extended_life_span1.21197744
74MP0000678_abnormal_parathyroid_gland1.21149839
75MP0000762_abnormal_tongue_morphology1.20636898
76MP0002697_abnormal_eye_size1.20198667
77MP0003111_abnormal_nucleus_morphology1.19238150
78MP0001697_abnormal_embryo_size1.16984816
79MP0002925_abnormal_cardiovascular_devel1.15070053
80MP0002089_abnormal_postnatal_growth/wei1.13750829
81MP0005248_abnormal_Harderian_gland1.13526768
82MP0008877_abnormal_DNA_methylation1.12961415
83MP0002269_muscular_atrophy1.10099870
84MP0003385_abnormal_body_wall1.07345772
85MP0001299_abnormal_eye_distance/1.06700985
86MP0006138_congestive_heart_failure1.06106883
87MP0001348_abnormal_lacrimal_gland1.04320453
88MP0005058_abnormal_lysosome_morphology1.03994856
89MP0001346_abnormal_lacrimal_gland1.02575837
90MP0003861_abnormal_nervous_system1.02560554
91MP0005621_abnormal_cell_physiology1.01115824
92MP0008438_abnormal_cutaneous_collagen1.00812537
93MP0010094_abnormal_chromosome_stability1.00562456
94MP0000350_abnormal_cell_proliferation0.99997799
95MP0000266_abnormal_heart_morphology0.98726729
96MP0002080_prenatal_lethality0.98205565
97MP0008057_abnormal_DNA_replication0.98162326
98MP0009384_cardiac_valve_regurgitation0.96132550
99MP0002108_abnormal_muscle_morphology0.95905568
100MP0005375_adipose_tissue_phenotype0.94866279
101MP0009278_abnormal_bone_marrow0.94365710
102MP0003942_abnormal_urinary_system0.94110057
103MP0000467_abnormal_esophagus_morphology0.93755530
104MP0004264_abnormal_extraembryonic_tissu0.91626089
105MP0000462_abnormal_digestive_system0.91219974
106MP0001293_anophthalmia0.91189662
107MP0002092_abnormal_eye_morphology0.91157898
108MP0004130_abnormal_muscle_cell0.86770986
109MP0005023_abnormal_wound_healing0.86710385
110MP0004036_abnormal_muscle_relaxation0.86361333
111MP0001915_intracranial_hemorrhage0.86042994
112MP0003315_abnormal_perineum_morphology0.86017142
113MP0002098_abnormal_vibrissa_morphology0.85720050
114MP0004185_abnormal_adipocyte_glucose0.85576767
115MP0002822_catalepsy0.85156012
116MP0005377_hearing/vestibular/ear_phenot0.84804088
117MP0003878_abnormal_ear_physiology0.84804088
118MP0002114_abnormal_axial_skeleton0.83814206
119MP0004811_abnormal_neuron_physiology0.83116487
120MP0005666_abnormal_adipose_tissue0.82349572
121MP0000767_abnormal_smooth_muscle0.81977092
122MP0002116_abnormal_craniofacial_bone0.81006679
123MP0008770_decreased_survivor_rate0.80810670
124MP0003937_abnormal_limbs/digits/tail_de0.80621152
125MP0002932_abnormal_joint_morphology0.79345622
126MP0002896_abnormal_bone_mineralization0.77985142
127MP0008775_abnormal_heart_ventricle0.75230442
128MP0003567_abnormal_fetal_cardiomyocyte0.74512796
129MP0000747_muscle_weakness0.74449871
130MP0003279_aneurysm0.73960367
131MP0004885_abnormal_endolymph0.72069041
132MP0001784_abnormal_fluid_regulation0.72009489
133MP0000432_abnormal_head_morphology0.71972057
134MP0004808_abnormal_hematopoietic_stem0.71256963
135MP0003635_abnormal_synaptic_transmissio0.71061551
136MP0005330_cardiomyopathy0.70377739
137MP0000759_abnormal_skeletal_muscle0.69287406

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)3.46038323
2Abnormality of the lower motor neuron (HP:0002366)3.44511482
3Hyperacusis (HP:0010780)3.43739302
4Premature rupture of membranes (HP:0001788)3.21041364
5Shallow orbits (HP:0000586)2.99991058
6Astrocytoma (HP:0009592)2.97531297
7Abnormality of the astrocytes (HP:0100707)2.97531297
8Ependymoma (HP:0002888)2.84297952
9Elfin facies (HP:0004428)2.78946305
10Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.78090345
11Short 4th metacarpal (HP:0010044)2.78090345
12Renovascular hypertension (HP:0100817)2.74703828
13Renal duplication (HP:0000075)2.71461229
14Macroorchidism (HP:0000053)2.69114698
15Broad face (HP:0000283)2.69087739
16Distal upper limb amyotrophy (HP:0007149)2.65449892
17Upper limb amyotrophy (HP:0009129)2.65449892
18Pointed chin (HP:0000307)2.58314387
19Flat acetabular roof (HP:0003180)2.57401396
20Insomnia (HP:0100785)2.55878079
21Bowel diverticulosis (HP:0005222)2.55284350
22Dysmetric saccades (HP:0000641)2.52602945
23Abnormality of the distal phalanx of the thumb (HP:0009617)2.50934105
24Hand muscle atrophy (HP:0009130)2.47947636
25Lymphangioma (HP:0100764)2.40510367
26Protrusio acetabuli (HP:0003179)2.33654285
27Distal lower limb amyotrophy (HP:0008944)2.33290283
28Abnormality of the 4th metacarpal (HP:0010012)2.32411449
29Advanced eruption of teeth (HP:0006288)2.30400931
30Subacute progressive viral hepatitis (HP:0006572)2.29892935
31Aneurysm (HP:0002617)2.27068783
32Overriding aorta (HP:0002623)2.24315081
33Selective tooth agenesis (HP:0001592)2.21886942
34Heterotopia (HP:0002282)2.20955397
35Glioma (HP:0009733)2.20162960
36Neoplasm of the heart (HP:0100544)2.18059735
37Increased nuchal translucency (HP:0010880)2.17791820
38Bladder diverticulum (HP:0000015)2.16502144
39Disproportionate tall stature (HP:0001519)2.16323772
40Ankyloglossia (HP:0010296)2.12687233
41Flat cornea (HP:0007720)2.11852819
42Centrally nucleated skeletal muscle fibers (HP:0003687)2.08899533
43Obstructive sleep apnea (HP:0002870)2.07479208
44Enlarged penis (HP:0000040)2.07188477
45Mitral valve prolapse (HP:0001634)2.06336955
46Short nail (HP:0001799)2.05258249
47Obsessive-compulsive behavior (HP:0000722)2.04236890
48Ankle contracture (HP:0006466)1.98787652
49Abnormality of the fingertips (HP:0001211)1.98279342
50Abnormality of the calcaneus (HP:0008364)1.98240827
51Resting tremor (HP:0002322)1.97407659
52Atrophic scars (HP:0001075)1.96235495
53Spinal rigidity (HP:0003306)1.95762953
54Bronchomalacia (HP:0002780)1.93372664
55Natal tooth (HP:0000695)1.92751063
56Arnold-Chiari malformation (HP:0002308)1.92676949
57Achilles tendon contracture (HP:0001771)1.92081414
58Broad thumb (HP:0011304)1.90715845
59Trigonocephaly (HP:0000243)1.88448367
60Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.87934219
61Medulloblastoma (HP:0002885)1.87668523
62Long eyelashes (HP:0000527)1.87249016
63Dislocated radial head (HP:0003083)1.86944424
64Germ cell neoplasia (HP:0100728)1.86893536
65Pseudobulbar signs (HP:0002200)1.86780611
66Biconcave vertebral bodies (HP:0004586)1.86704207
67Asymmetry of the thorax (HP:0001555)1.86337379
68Narrow palate (HP:0000189)1.85552839
69Wormian bones (HP:0002645)1.85302610
70Abnormality of the distal phalanges of the toes (HP:0010182)1.85031225
71Abnormality of oral frenula (HP:0000190)1.84879084
72Vertebral compression fractures (HP:0002953)1.84518378
73Broad metatarsal (HP:0001783)1.84308490
74Difficulty running (HP:0009046)1.84303750
75Dilatation of the ascending aorta (HP:0005111)1.84230439
76Broad distal phalanx of finger (HP:0009836)1.82516750
77Increased variability in muscle fiber diameter (HP:0003557)1.81587017
78Fragile skin (HP:0001030)1.80897573
79Abnormal ossification of hand bones (HP:0005921)1.79549512
80Long toe (HP:0010511)1.79405375
81Termporal pattern (HP:0011008)1.78730630
82Insidious onset (HP:0003587)1.78730630
83Bundle branch block (HP:0011710)1.78663235
84Hypopigmentation of the fundus (HP:0007894)1.78409308
85Right ventricular cardiomyopathy (HP:0011663)1.77773166
86Fibroma (HP:0010614)1.76130734
87Patellar dislocation (HP:0002999)1.76038747
88Osteolytic defects of the phalanges of the hand (HP:0009771)1.75538984
89Osteolytic defects of the hand bones (HP:0009699)1.75538984
90Sparse lateral eyebrow (HP:0005338)1.75420711
91Vertebral arch anomaly (HP:0008438)1.75168197
92Proximal placement of thumb (HP:0009623)1.74854706
93Urethral obstruction (HP:0000796)1.74082886
94Abnormality of dentin (HP:0010299)1.72939254
95Fibrous tissue neoplasm (HP:0012316)1.72896906
96Genu recurvatum (HP:0002816)1.71637666
97Abnormality of the Achilles tendon (HP:0005109)1.71597637
98Syringomyelia (HP:0003396)1.71304798
99Spinal cord lesions (HP:0100561)1.71304798
100Abnormality of the radial head (HP:0003995)1.71279639
101Mitral regurgitation (HP:0001653)1.71273275
102Mildly elevated creatine phosphokinase (HP:0008180)1.71162974
103Cervical subluxation (HP:0003308)1.70898979
104Aortic aneurysm (HP:0004942)1.70552925
105Annular pancreas (HP:0001734)1.69946480
106Abnormality of the phalanges of the hallux (HP:0010057)1.69934928
107Aplasia of the phalanges of the hand (HP:0009802)1.69396580
108Aplasia involving bones of the extremities (HP:0009825)1.69396580
109Aplasia involving bones of the upper limbs (HP:0009823)1.69396580
110Missing ribs (HP:0000921)1.68210497
111Precocious puberty (HP:0000826)1.67757027
112Sandal gap (HP:0001852)1.67693113
113High pitched voice (HP:0001620)1.67412541
114Premature skin wrinkling (HP:0100678)1.66702002
115Neoplasm of the oral cavity (HP:0100649)1.66693626
116Persistence of primary teeth (HP:0006335)1.66572861
117Trismus (HP:0000211)1.66388994
118Hallux valgus (HP:0001822)1.66257432
119Malignant gastrointestinal tract tumors (HP:0006749)1.66028743
120Gastrointestinal carcinoma (HP:0002672)1.66028743
121Abnormality of the salivary glands (HP:0010286)1.65610645
122Deviation of the hallux (HP:0010051)1.65449715
123Hemiplegia (HP:0002301)1.64740565
124Difficulty climbing stairs (HP:0003551)1.64517222
125Distal lower limb muscle weakness (HP:0009053)1.64481757
126Arterial tortuosity (HP:0005116)1.63969735
127Abnormality of the diencephalon (HP:0010662)1.63882562
128Hammertoe (HP:0001765)1.63746373
129Hepatoblastoma (HP:0002884)1.63284602
130Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.63010436
131Turricephaly (HP:0000262)1.61976784
132Exostoses (HP:0100777)1.61293428
133Abnormality of carpal bone ossification (HP:0006257)1.61208692
134Septate vagina (HP:0001153)1.61056192
135Broad phalanges of the hand (HP:0009768)1.60205523
136Megalocornea (HP:0000485)1.60049556
137Abnormality of skeletal muscle fiber size (HP:0012084)1.59655729
138Blue sclerae (HP:0000592)1.59313972
139Midface retrusion (HP:0011800)1.57660631
140Thin ribs (HP:0000883)1.57599412
141Deviation of the thumb (HP:0009603)1.57164878
142Rectal prolapse (HP:0002035)1.55345176
143Skull defect (HP:0001362)1.55072542
144Ulnar bowing (HP:0003031)1.54466132
145Back pain (HP:0003418)1.53309341
146Hypoplastic ischia (HP:0003175)1.52839976
147Truncal obesity (HP:0001956)1.52687108
148Hyporeflexia of lower limbs (HP:0002600)1.52159961
149Broad finger (HP:0001500)1.51691826
150Sacral dimple (HP:0000960)1.50870438
151Broad palm (HP:0001169)1.50820492
152Spina bifida occulta (HP:0003298)1.50495367
153Lower limb amyotrophy (HP:0007210)1.50118654
154Increased connective tissue (HP:0009025)1.49528435
155Neoplasm of striated muscle (HP:0009728)1.49245214
156Volvulus (HP:0002580)1.48746119
157Scapular winging (HP:0003691)1.47988071
158Long palpebral fissure (HP:0000637)1.47941076
159Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.47342755
160Buphthalmos (HP:0000557)1.47220262
161Absent frontal sinuses (HP:0002688)1.46786734
162Anal stenosis (HP:0002025)1.45677063

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.82898913
2TRIB33.65150187
3CDK123.63643565
4PKN23.38520694
5EEF2K3.01507228
6PRKD32.53053932
7MAP3K102.46844688
8LATS12.31009401
9RIPK12.30400788
10PDGFRA2.17344715
11TTN2.00121187
12ICK1.98326083
13NEK11.84368660
14PRPF4B1.78626438
15BRD41.72642007
16PTK61.68738133
17TYRO31.62246794
18MAP3K91.58995392
19SIK11.55449549
20CAMK1G1.55048794
21ALK1.51381937
22CAMK1D1.51070214
23MTOR1.50226467
24DDR21.47197017
25NEK21.46886857
26PAK61.46607603
27SCYL21.38915366
28LATS21.36414112
29LMTK21.30322492
30KSR11.28337324
31IRAK31.24980456
32KSR21.24033987
33RET1.12405018
34CDC71.12171726
35STK381.10458978
36SIK21.06907701
37CAMKK11.06448587
38BMX1.06042436
39DMPK1.05674312
40NTRK31.05447045
41FGFR21.04166629
42PTK21.04161589
43FGFR11.01261677
44CDK71.00970312
45MAP3K70.99461448
46MST1R0.98078646
47CDC42BPA0.91015566
48PDGFRB0.89802288
49PAK20.89711636
50PAK30.89628103
51FGFR40.89550743
52MAP3K40.87496915
53EPHA20.86781172
54EPHA40.86749829
55DAPK20.86201574
56MAP3K20.85657459
57SGK30.85034620
58MET0.84639169
59PRKCH0.82859122
60TAOK10.82553577
61CDK60.81130825
62AKT30.80597572
63PASK0.77525033
64FER0.77006415
65MAP3K130.74568062
66PAK40.74410808
67PDK30.73878077
68PDK40.73878077
69CDK40.72084613
70FGFR30.68426893
71NTRK20.67738841
72BRAF0.67620208
73ERBB20.65187655
74ERN10.64219631
75STK30.63366599
76DYRK1B0.61721295
77WNK10.60638065
78MARK20.60266983
79MAPK110.59256404
80RPS6KA20.58516984
81ARAF0.57269907
82CAMK40.56968496
83PDPK10.56759586
84PRKAA10.56103634
85TESK10.55593733
86RPS6KC10.55221719
87RPS6KL10.55221719
88* CHEK10.54392129
89CDK90.53594785
90NTRK10.53419182
91EPHB10.51581923
92TTK0.50817079
93LRRK20.49598048
94* CDK20.49424871
95STK110.48619691
96CHEK20.48560566
97TSSK60.48413691
98MAP2K20.48237611
99NEK60.47040308
100PRKD10.47013397
101MAP3K80.46341356
102EPHB20.46326263
103ATR0.45795702
104CSNK1D0.45697608
105RPS6KB20.45174641
106MINK10.44754766
107MAPK100.44524533
108MAP2K30.44443406
109AURKA0.44229350
110CSNK1E0.44201940
111AKT20.42772351
112PRKD20.42492893
113MAPK80.41477720
114NME20.41117188
115SRPK10.40684881
116* GSK3B0.40626793
117* RPS6KA30.40085355
118ATM0.39392973
119MELK0.39319494
120MAP3K60.39154081
121CDK10.38675897
122EPHA30.38057005
123* PRKDC0.37692125
124UHMK10.37048091
125ROCK10.36876690
126TAOK20.36765185
127PHKG20.36633042
128RPS6KA10.36501594
129RPS6KB10.35701018
130ERBB40.35193163
131CDK150.34870740
132STK40.33989556
133CDK11A0.33926839
134TESK20.32391749
135NEK90.32201221
136AURKB0.31633905
137CLK10.30974082

Predicted pathways (KEGG)

RankGene SetZ-score
1Lysine degradation_Homo sapiens_hsa003101.84186142
2Nitrogen metabolism_Homo sapiens_hsa009101.83577949
3mTOR signaling pathway_Homo sapiens_hsa041501.74033134
4Thyroid hormone signaling pathway_Homo sapiens_hsa049191.55234411
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.51681173
6Type II diabetes mellitus_Homo sapiens_hsa049301.51292134
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.49495472
8Endometrial cancer_Homo sapiens_hsa052131.46716105
9Central carbon metabolism in cancer_Homo sapiens_hsa052301.43511875
10Glioma_Homo sapiens_hsa052141.42681208
11Adherens junction_Homo sapiens_hsa045201.41859234
12Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.41741429
13Chronic myeloid leukemia_Homo sapiens_hsa052201.39789861
14Dilated cardiomyopathy_Homo sapiens_hsa054141.33609032
15Hippo signaling pathway_Homo sapiens_hsa043901.33465075
16Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.33064696
17Basal cell carcinoma_Homo sapiens_hsa052171.32081130
18Acute myeloid leukemia_Homo sapiens_hsa052211.30444374
19Proteoglycans in cancer_Homo sapiens_hsa052051.30294365
20Focal adhesion_Homo sapiens_hsa045101.29941809
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.27718371
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.26958836
23Non-small cell lung cancer_Homo sapiens_hsa052231.26440749
24Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.25806878
25Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.24889942
26Dorso-ventral axis formation_Homo sapiens_hsa043201.24183756
27Glucagon signaling pathway_Homo sapiens_hsa049221.22205683
28Prion diseases_Homo sapiens_hsa050201.21541998
29Pentose phosphate pathway_Homo sapiens_hsa000301.19035580
30MicroRNAs in cancer_Homo sapiens_hsa052061.18763402
31Estrogen signaling pathway_Homo sapiens_hsa049151.18326292
32Cell cycle_Homo sapiens_hsa041101.16425435
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.14565330
34DNA replication_Homo sapiens_hsa030301.14551681
35Longevity regulating pathway - mammal_Homo sapiens_hsa042111.14154651
36Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.12520514
37Small cell lung cancer_Homo sapiens_hsa052221.12013117
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.11990146
39Long-term potentiation_Homo sapiens_hsa047201.11931270
40Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.11530294
41Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11264160
42Insulin resistance_Homo sapiens_hsa049311.10776120
43Hedgehog signaling pathway_Homo sapiens_hsa043401.10269108
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.10178303
45Colorectal cancer_Homo sapiens_hsa052101.08627168
46Bladder cancer_Homo sapiens_hsa052191.08201508
47Notch signaling pathway_Homo sapiens_hsa043301.07247079
48Insulin secretion_Homo sapiens_hsa049111.06009905
49Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.04610057
50Insulin signaling pathway_Homo sapiens_hsa049101.04326209
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.04016241
52Neurotrophin signaling pathway_Homo sapiens_hsa047221.02387331
53Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.00685046
54Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00532685
552-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.99621564
56Tight junction_Homo sapiens_hsa045300.99089703
57mRNA surveillance pathway_Homo sapiens_hsa030150.97281966
58Other glycan degradation_Homo sapiens_hsa005110.97118654
59AMPK signaling pathway_Homo sapiens_hsa041520.96621589
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95977292
61ErbB signaling pathway_Homo sapiens_hsa040120.95078599
62Vitamin B6 metabolism_Homo sapiens_hsa007500.94954442
63ECM-receptor interaction_Homo sapiens_hsa045120.94903181
64Fructose and mannose metabolism_Homo sapiens_hsa000510.94547619
65Oxytocin signaling pathway_Homo sapiens_hsa049210.93970865
66Gap junction_Homo sapiens_hsa045400.93780091
67Olfactory transduction_Homo sapiens_hsa047400.93293925
68Inositol phosphate metabolism_Homo sapiens_hsa005620.92537348
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91783062
70Melanogenesis_Homo sapiens_hsa049160.91781744
71Circadian entrainment_Homo sapiens_hsa047130.90133314
72Oocyte meiosis_Homo sapiens_hsa041140.89924556
73Choline metabolism in cancer_Homo sapiens_hsa052310.89782519
74VEGF signaling pathway_Homo sapiens_hsa043700.88286855
75Renal cell carcinoma_Homo sapiens_hsa052110.86989951
76Fatty acid biosynthesis_Homo sapiens_hsa000610.86204728
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86086058
78GnRH signaling pathway_Homo sapiens_hsa049120.85794217
79Wnt signaling pathway_Homo sapiens_hsa043100.85722012
80Gastric acid secretion_Homo sapiens_hsa049710.85020745
81Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.84753068
82Amphetamine addiction_Homo sapiens_hsa050310.81738629
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.81722825
84Bile secretion_Homo sapiens_hsa049760.80460086
85Dopaminergic synapse_Homo sapiens_hsa047280.79821706
86Cocaine addiction_Homo sapiens_hsa050300.77266393
87Rap1 signaling pathway_Homo sapiens_hsa040150.77254322
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.77082966
89Carbon metabolism_Homo sapiens_hsa012000.76731713
90Cholinergic synapse_Homo sapiens_hsa047250.76160680
91Axon guidance_Homo sapiens_hsa043600.75326557
92Renin secretion_Homo sapiens_hsa049240.75130353
93Thyroid cancer_Homo sapiens_hsa052160.74653931
94Spliceosome_Homo sapiens_hsa030400.74113792
95Pancreatic cancer_Homo sapiens_hsa052120.73341258
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73248901
97Amoebiasis_Homo sapiens_hsa051460.73176196
98cAMP signaling pathway_Homo sapiens_hsa040240.73173506
99Melanoma_Homo sapiens_hsa052180.71766711
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.71073091
101Viral myocarditis_Homo sapiens_hsa054160.69683604
102HTLV-I infection_Homo sapiens_hsa051660.68973910
103AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68717933
104Biosynthesis of amino acids_Homo sapiens_hsa012300.68688057
105HIF-1 signaling pathway_Homo sapiens_hsa040660.67953971
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67381631
107Salivary secretion_Homo sapiens_hsa049700.67122188
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.66448510
109N-Glycan biosynthesis_Homo sapiens_hsa005100.66387932
110Prolactin signaling pathway_Homo sapiens_hsa049170.66248244
111Pathways in cancer_Homo sapiens_hsa052000.65517741
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65321846
113Galactose metabolism_Homo sapiens_hsa000520.65083314
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.64946431
115Vibrio cholerae infection_Homo sapiens_hsa051100.64595592
116RNA transport_Homo sapiens_hsa030130.64584319
117Thyroid hormone synthesis_Homo sapiens_hsa049180.64295334
118Viral carcinogenesis_Homo sapiens_hsa052030.63147919
119Alcoholism_Homo sapiens_hsa050340.62075762
120TGF-beta signaling pathway_Homo sapiens_hsa043500.61121238
121Prostate cancer_Homo sapiens_hsa052150.61095419
122FoxO signaling pathway_Homo sapiens_hsa040680.60782575
123Arginine biosynthesis_Homo sapiens_hsa002200.60392406
124Protein digestion and absorption_Homo sapiens_hsa049740.60359123
125PI3K-Akt signaling pathway_Homo sapiens_hsa041510.56929209
126Sphingolipid signaling pathway_Homo sapiens_hsa040710.56916106
127Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54537365

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