GTF2F2P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule catabolic process (GO:0016998)9.14036888
2cell wall macromolecule metabolic process (GO:0044036)7.83192864
3auditory receptor cell differentiation (GO:0042491)6.88086051
4acrosome assembly (GO:0001675)6.47728669
5rRNA methylation (GO:0031167)6.47307407
6cellular extravasation (GO:0045123)6.41214996
7rRNA modification (GO:0000154)5.77511521
8positive regulation of phosphoprotein phosphatase activity (GO:0032516)5.72699001
9positive regulation of inositol phosphate biosynthetic process (GO:0060732)5.67878709
10myelin assembly (GO:0032288)5.34251733
11positive regulation of uterine smooth muscle contraction (GO:0070474)5.14217281
12positive regulation of mast cell activation involved in immune response (GO:0033008)4.81137569
13positive regulation of mast cell degranulation (GO:0043306)4.81137569
14glomerular visceral epithelial cell development (GO:0072015)4.77636545
15regulation of cytokine secretion involved in immune response (GO:0002739)4.67993714
16negative regulation of Rho protein signal transduction (GO:0035024)4.62944076
17negative regulation of smooth muscle cell migration (GO:0014912)4.60665538
18positive regulation of macrophage activation (GO:0043032)4.56424648
19positive regulation of actin filament depolymerization (GO:0030836)4.54075616
20hair cell differentiation (GO:0035315)4.48600258
21phagocytosis, recognition (GO:0006910)4.45897170
22regulation of MHC class II biosynthetic process (GO:0045346)4.41754069
23phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)4.29010014
24Notch signaling involved in heart development (GO:0061314)4.19035510
25cAMP catabolic process (GO:0006198)4.13457720
26glomerular epithelial cell development (GO:0072310)4.11401563
27positive regulation of mast cell activation (GO:0033005)4.10114894
28cyclic nucleotide catabolic process (GO:0009214)4.09953279
29cardiac right ventricle morphogenesis (GO:0003215)4.02587909
30regulation of inositol phosphate biosynthetic process (GO:0010919)4.01319952
31transcription from mitochondrial promoter (GO:0006390)3.99625553
32negative regulation of stress fiber assembly (GO:0051497)3.93781759
33regulation of uterine smooth muscle contraction (GO:0070472)3.93678397
34regulation of timing of cell differentiation (GO:0048505)3.91215477
35regulation of gene silencing by RNA (GO:0060966)3.82177320
36regulation of posttranscriptional gene silencing (GO:0060147)3.82177320
37regulation of gene silencing by miRNA (GO:0060964)3.82177320
38regulation of cilium movement (GO:0003352)3.81896704
39TOR signaling (GO:0031929)3.81090574
40negative regulation of actin filament bundle assembly (GO:0032232)3.70559213
41positive regulation of smooth muscle cell migration (GO:0014911)3.69260237
42ventricular cardiac muscle cell development (GO:0055015)3.63181135
43regulation of development, heterochronic (GO:0040034)3.56207112
44mitochondrial RNA metabolic process (GO:0000959)3.55226460
45regulation of hippo signaling (GO:0035330)3.52240876
46negative regulation of cell cycle arrest (GO:0071157)3.52188619
47DNA double-strand break processing (GO:0000729)3.51018818
48positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.50899648
49corticosteroid receptor signaling pathway (GO:0031958)3.47734669
50retinal rod cell development (GO:0046548)3.41715185
51negative regulation of axon extension involved in axon guidance (GO:0048843)3.41021231
52fibroblast migration (GO:0010761)3.40310604
53regulation of DNA damage checkpoint (GO:2000001)3.39641002
54phosphorelay signal transduction system (GO:0000160)3.38086573
55detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.36488594
56nonmotile primary cilium assembly (GO:0035058)3.29253685
57regulation of transcription from RNA polymerase III promoter (GO:0006359)3.27937817
58ribosome assembly (GO:0042255)3.26694784
59relaxation of smooth muscle (GO:0044557)3.25120170
60positive regulation of ERBB signaling pathway (GO:1901186)3.24993408
61interkinetic nuclear migration (GO:0022027)3.18686682
62inner ear receptor cell differentiation (GO:0060113)3.18126224
63positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517)3.17180556
64sperm-egg recognition (GO:0035036)3.17180518
65establishment of viral latency (GO:0019043)3.13824434
66positive regulation of leukocyte degranulation (GO:0043302)3.05140560
67neuronal stem cell maintenance (GO:0097150)3.04014851
68positive regulation of phosphatase activity (GO:0010922)3.00972617
69aspartate family amino acid catabolic process (GO:0009068)2.98773574
70negative regulation of axon guidance (GO:1902668)2.98771663
71branching involved in prostate gland morphogenesis (GO:0060442)2.98439374
72positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742)2.94661977
73vasodilation (GO:0042311)2.92870839
74positive regulation of monocyte chemotaxis (GO:0090026)2.90130019
75protein polyglutamylation (GO:0018095)2.87484927
76indolalkylamine metabolic process (GO:0006586)2.87414406
77chondrocyte proliferation (GO:0035988)2.86061320
78microtubule anchoring (GO:0034453)2.84829653
79cellular response to leptin stimulus (GO:0044320)2.84468319
80regulation of response to food (GO:0032095)2.84018823
81iron ion import (GO:0097286)2.83241373
82positive regulation of dephosphorylation (GO:0035306)2.81531156
83positive regulation of neurotransmitter secretion (GO:0001956)2.79539434
84replicative senescence (GO:0090399)2.78785701
85cilium morphogenesis (GO:0060271)2.75932124
86carnitine metabolic process (GO:0009437)2.75838987
87ventricular system development (GO:0021591)2.74466001
88negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.74302595
89negative regulation of lipase activity (GO:0060192)2.74155401
90regulation of execution phase of apoptosis (GO:1900117)2.71204350
91wound healing, spreading of epidermal cells (GO:0035313)2.70845862
92positive regulation of fatty acid transport (GO:2000193)2.70709017
93positive regulation of icosanoid secretion (GO:0032305)2.66967416
94tRNA aminoacylation for protein translation (GO:0006418)2.66920728
95negative regulation of systemic arterial blood pressure (GO:0003085)2.60239145
96response to leptin (GO:0044321)2.57430024
97female gonad development (GO:0008585)2.55768970
98amino acid activation (GO:0043038)2.55049135
99tRNA aminoacylation (GO:0043039)2.55049135
100cell-cell recognition (GO:0009988)2.54395900

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.81351008
2VDR_22108803_ChIP-Seq_LS180_Human3.80901934
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.70567793
4ZNF274_21170338_ChIP-Seq_K562_Hela3.09113507
5FUS_26573619_Chip-Seq_HEK293_Human2.61317695
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.60615027
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.58388431
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.56249450
9EWS_26573619_Chip-Seq_HEK293_Human2.52332413
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.46753099
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29463766
12TAF15_26573619_Chip-Seq_HEK293_Human2.21239944
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.17523342
14CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.07710978
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.03351827
16CTBP2_25329375_ChIP-Seq_LNCAP_Human2.01142445
17GABP_17652178_ChIP-ChIP_JURKAT_Human1.97412162
18EST1_17652178_ChIP-ChIP_JURKAT_Human1.96894672
19EGR1_23403033_ChIP-Seq_LIVER_Mouse1.93809017
20ELK1_19687146_ChIP-ChIP_HELA_Human1.91543303
21UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.83785883
22PCGF2_27294783_Chip-Seq_NPCs_Mouse1.80648602
23TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.80140605
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.78231877
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.75515184
26P300_19829295_ChIP-Seq_ESCs_Human1.72181427
27KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.69363726
28SMAD4_21799915_ChIP-Seq_A2780_Human1.65368832
29ER_23166858_ChIP-Seq_MCF-7_Human1.64995646
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.64435958
31CDX2_22108803_ChIP-Seq_LS180_Human1.61389634
32PADI4_21655091_ChIP-ChIP_MCF-7_Human1.59940977
33CBP_20019798_ChIP-Seq_JUKART_Human1.56791944
34IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.56791944
35CRX_20693478_ChIP-Seq_RETINA_Mouse1.56697828
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.54816820
37BCAT_22108803_ChIP-Seq_LS180_Human1.53405557
38IRF1_19129219_ChIP-ChIP_H3396_Human1.52894781
39OCT4_21477851_ChIP-Seq_ESCs_Mouse1.49219847
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.46337182
41STAT3_23295773_ChIP-Seq_U87_Human1.44761513
42TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43537948
43EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.43431900
44TP53_16413492_ChIP-PET_HCT116_Human1.42299866
45FLI1_21867929_ChIP-Seq_TH2_Mouse1.41539280
46MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.41330853
47SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.40727560
48VDR_23849224_ChIP-Seq_CD4+_Human1.40618720
49AR_25329375_ChIP-Seq_VCAP_Human1.40327592
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39950292
51TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.39581179
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.38291370
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38191981
54SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37359686
55OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35942310
56TCF4_22108803_ChIP-Seq_LS180_Human1.33929203
57TCF4_23295773_ChIP-Seq_U87_Human1.32480165
58KLF5_20875108_ChIP-Seq_MESCs_Mouse1.32175705
59P53_22387025_ChIP-Seq_ESCs_Mouse1.30830744
60SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.29245373
61MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.28629244
62CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27123780
63HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.26927111
64PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.26860619
65SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26442033
66LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25466316
67RUNX2_22187159_ChIP-Seq_PCA_Human1.24257287
68E2F1_18555785_Chip-Seq_ESCs_Mouse1.24053863
69KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.23214365
70RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.22440986
71TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.22211223
72NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.18266896
73PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17726290
74NFE2_27457419_Chip-Seq_LIVER_Mouse1.16067362
75GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.13755104
76CMYC_18555785_Chip-Seq_ESCs_Mouse1.13481916
77SOX2_19829295_ChIP-Seq_ESCs_Human1.12848084
78NANOG_19829295_ChIP-Seq_ESCs_Human1.12848084
79SALL4_22934838_ChIP-ChIP_CD34+_Human1.12074422
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11573014
81STAT3_18555785_Chip-Seq_ESCs_Mouse1.11492026
82MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.10535781
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.10048355
84TBX3_20139965_ChIP-Seq_ESCs_Mouse1.08118577
85SMAD3_21741376_ChIP-Seq_HESCs_Human1.07465373
86SMAD_19615063_ChIP-ChIP_OVARY_Human1.07363809
87BRD4_25478319_ChIP-Seq_HGPS_Human1.07181094
88TBX3_20139965_ChIP-Seq_MESCs_Mouse1.06800601
89FOXM1_26456572_ChIP-Seq_MCF-7_Human1.06737443
90TP53_22573176_ChIP-Seq_HFKS_Human1.06549837
91SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05195517
92SRF_21415370_ChIP-Seq_HL-1_Mouse1.04574037
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04539590
94SOX2_18555785_Chip-Seq_ESCs_Mouse1.02252521
95P300_18555785_Chip-Seq_ESCs_Mouse1.01967303
96POU5F1_16153702_ChIP-ChIP_HESCs_Human0.98248499
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97206117
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96705091
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96705091
100AR_20517297_ChIP-Seq_VCAP_Human0.96623502

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue4.21697740
2MP0008789_abnormal_olfactory_epithelium4.01881241
3MP0004147_increased_porphyrin_level3.67530668
4MP0004272_abnormal_basement_membrane3.27030074
5MP0002938_white_spotting3.23098544
6MP0001661_extended_life_span3.16668313
7MP0005499_abnormal_olfactory_system2.87939822
8MP0005394_taste/olfaction_phenotype2.87939822
9MP0010030_abnormal_orbit_morphology2.82546882
10MP0003195_calcinosis2.78616341
11MP0001984_abnormal_olfaction2.72405474
12MP0008260_abnormal_autophagy2.61422516
13MP0008877_abnormal_DNA_methylation2.48111151
14MP0005085_abnormal_gallbladder_physiolo2.47706273
15MP0000569_abnormal_digit_pigmentation2.33016826
16MP0005551_abnormal_eye_electrophysiolog2.30767347
17MP0003567_abnormal_fetal_cardiomyocyte2.24947655
18MP0005670_abnormal_white_adipose2.21682765
19MP0000516_abnormal_urinary_system2.16592170
20MP0005367_renal/urinary_system_phenotyp2.16592170
21MP0004133_heterotaxia1.95858934
22MP0010234_abnormal_vibrissa_follicle1.89392363
23MP0005332_abnormal_amino_acid1.84400351
24MP0002876_abnormal_thyroid_physiology1.82715889
25MP0000566_synostosis1.81481173
26MP0006054_spinal_hemorrhage1.75521306
27MP0004215_abnormal_myocardial_fiber1.62810553
28MP0003252_abnormal_bile_duct1.62090002
29MP0001986_abnormal_taste_sensitivity1.53809436
30MP0003566_abnormal_cell_adhesion1.47428251
31MP0000749_muscle_degeneration1.46331258
32MP0008775_abnormal_heart_ventricle1.44211064
33MP0003122_maternal_imprinting1.43668513
34MP0004233_abnormal_muscle_weight1.42534575
35MP0009046_muscle_twitch1.42421128
36MP0003137_abnormal_impulse_conducting1.41579246
37MP0005620_abnormal_muscle_contractility1.32486776
38MP0009697_abnormal_copulation1.31432272
39MP0010329_abnormal_lipoprotein_level1.30378571
40MP0000639_abnormal_adrenal_gland1.21939532
41MP0003011_delayed_dark_adaptation1.18779956
42MP0003656_abnormal_erythrocyte_physiolo1.16921489
43MP0002127_abnormal_cardiovascular_syste1.16476900
44MP0008875_abnormal_xenobiotic_pharmacok1.14942030
45MP0002972_abnormal_cardiac_muscle1.14549794
46MP0005075_abnormal_melanosome_morpholog1.13874575
47MP0000470_abnormal_stomach_morphology1.13204591
48MP0005310_abnormal_salivary_gland1.13046979
49MP0004742_abnormal_vestibular_system1.11897136
50MP0010094_abnormal_chromosome_stability1.09707888
51MP0002233_abnormal_nose_morphology1.07197673
52MP0003880_abnormal_central_pattern1.06333320
53MP0002160_abnormal_reproductive_system1.05672385
54MP0000230_abnormal_systemic_arterial1.03002894
55MP0000372_irregular_coat_pigmentation1.01185155
56MP0003121_genomic_imprinting0.98431374
57MP0000013_abnormal_adipose_tissue0.97883301
58MP0006035_abnormal_mitochondrial_morpho0.97826893
59MP0001324_abnormal_eye_pigmentation0.97531325
60MP0005360_urolithiasis0.96781178
61MP0005253_abnormal_eye_physiology0.96699247
62MP0005408_hypopigmentation0.94982061
63MP0002272_abnormal_nervous_system0.92921686
64MP0003718_maternal_effect0.91997450
65MP0000428_abnormal_craniofacial_morphol0.89532572
66MP0005595_abnormal_vascular_smooth0.88257530
67MP0001929_abnormal_gametogenesis0.88170959
68MP0003786_premature_aging0.87715432
69MP0010678_abnormal_skin_adnexa0.86007578
70MP0003698_abnormal_male_reproductive0.84601577
71MP0004957_abnormal_blastocyst_morpholog0.83799952
72MP0005195_abnormal_posterior_eye0.83606160
73MP0001501_abnormal_sleep_pattern0.83225223
74MP0001145_abnormal_male_reproductive0.79137394
75MP0000653_abnormal_sex_gland0.78619053
76MP0005174_abnormal_tail_pigmentation0.77984437
77MP0004270_analgesia0.76374430
78MP0001485_abnormal_pinna_reflex0.74363109
79MP0002928_abnormal_bile_duct0.74354340
80MP0002006_tumorigenesis0.70404396
81MP0000751_myopathy0.70011608
82MP0002734_abnormal_mechanical_nocicepti0.68393111
83MP0009384_cardiac_valve_regurgitation0.68200813
84MP0002108_abnormal_muscle_morphology0.67923348
85MP0002254_reproductive_system_inflammat0.65605075
86MP0000427_abnormal_hair_cycle0.65483299
87MP0005636_abnormal_mineral_homeostasis0.64216729
88MP0002925_abnormal_cardiovascular_devel0.64211299
89MP0008995_early_reproductive_senescence0.63827401
90MP0003119_abnormal_digestive_system0.63716989
91MP0009703_decreased_birth_body0.63224822
92MP0002210_abnormal_sex_determination0.62960747
93MP0002269_muscular_atrophy0.60285410
94MP0001915_intracranial_hemorrhage0.56395906
95MP0005410_abnormal_fertilization0.56301073
96MP0005395_other_phenotype0.56216375
97MP0004264_abnormal_extraembryonic_tissu0.56051248
98MP0004085_abnormal_heartbeat0.55337360
99MP0002557_abnormal_social/conspecific_i0.55260514
100MP0003890_abnormal_embryonic-extraembry0.54340786

Predicted human phenotypes

RankGene SetZ-score
1Short tibia (HP:0005736)4.64194232
2Aplasia/Hypoplasia of the tibia (HP:0005772)4.58162143
3Retinal dysplasia (HP:0007973)4.55766478
4Type II lissencephaly (HP:0007260)4.48832564
5Exercise-induced muscle cramps (HP:0003710)4.44860080
6Metaphyseal dysplasia (HP:0100255)4.32479357
7Bifid tongue (HP:0010297)4.18642666
8Hypokinesia (HP:0002375)4.06805982
9Chorioretinal atrophy (HP:0000533)3.95097628
10Abnormality of midbrain morphology (HP:0002418)3.60612779
11Molar tooth sign on MRI (HP:0002419)3.60612779
12Abnormality of alanine metabolism (HP:0010916)3.48546723
13Hyperalaninemia (HP:0003348)3.48546723
14Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.48546723
15Cerebellar dysplasia (HP:0007033)3.40699109
16Median cleft lip (HP:0000161)3.30629290
17Diminished movement (HP:0002374)3.28745378
18Abnormality of the anterior horn cell (HP:0006802)3.22852017
19Degeneration of anterior horn cells (HP:0002398)3.22852017
20Microglossia (HP:0000171)3.15281447
21Gastrointestinal atresia (HP:0002589)3.07414808
22Pancreatic fibrosis (HP:0100732)3.02377563
23Fair hair (HP:0002286)3.01734222
24Increased serum pyruvate (HP:0003542)2.93355501
25Abnormal biliary tract morphology (HP:0012440)2.92584266
26Genital tract atresia (HP:0001827)2.92408920
27Anterior segment dysgenesis (HP:0007700)2.76748349
28Pancreatic cysts (HP:0001737)2.73495981
29Preaxial foot polydactyly (HP:0001841)2.71403372
30Pulmonary artery stenosis (HP:0004415)2.65835979
31Gaze-evoked nystagmus (HP:0000640)2.59092322
32Congenital, generalized hypertrichosis (HP:0004540)2.58764263
33Large for gestational age (HP:0001520)2.52390657
34Gait imbalance (HP:0002141)2.50510697
35Abnormality of glycolysis (HP:0004366)2.49487966
36Abnormality of lateral ventricle (HP:0030047)2.48269724
37Papillary thyroid carcinoma (HP:0002895)2.47994524
38Medial flaring of the eyebrow (HP:0010747)2.47605549
39Congenital primary aphakia (HP:0007707)2.46027904
40Abnormality of chromosome stability (HP:0003220)2.42837504
41Vertebral arch anomaly (HP:0008438)2.33322148
42Neonatal respiratory distress (HP:0002643)2.31558211
43Aplasia/Hypoplasia of the tongue (HP:0010295)2.31299651
44Chronic hepatic failure (HP:0100626)2.30388048
45Abolished electroretinogram (ERG) (HP:0000550)2.28576067
46Broad-based gait (HP:0002136)2.25717123
47Neoplasm of the adrenal gland (HP:0100631)2.23295826
48Squamous cell carcinoma (HP:0002860)2.22802640
49Amyotrophic lateral sclerosis (HP:0007354)2.18994034
50Thyroid carcinoma (HP:0002890)2.18615968
51Poor coordination (HP:0002370)2.17256151
52Biliary tract neoplasm (HP:0100574)2.14802189
53Prolonged neonatal jaundice (HP:0006579)2.11643641
54Neoplasm of the adrenal cortex (HP:0100641)2.11444138
55Aplasia/Hypoplasia of the uvula (HP:0010293)2.11028872
56Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.09534660
57Meckel diverticulum (HP:0002245)2.08552415
58Cutaneous melanoma (HP:0012056)2.08342881
59Hemiparesis (HP:0001269)2.07404724
60Nephrogenic diabetes insipidus (HP:0009806)2.06095749
61Mutism (HP:0002300)2.01581247
62Abnormality of serum amino acid levels (HP:0003112)2.00272481
63Vaginal atresia (HP:0000148)2.00208265
64Aplasia/Hypoplasia of the hallux (HP:0008362)1.99993275
65Renal hypoplasia (HP:0000089)1.99062609
66Hyperventilation (HP:0002883)1.98328845
67Hypothermia (HP:0002045)1.97575664
68Short hallux (HP:0010109)1.96764354
69Cupped ear (HP:0000378)1.93621680
70Subcapsular cataract (HP:0000523)1.93237517
71Furrowed tongue (HP:0000221)1.91904964
72Abnormality of the ileum (HP:0001549)1.90858623
73Porencephaly (HP:0002132)1.88806711
74Tubulointerstitial nephritis (HP:0001970)1.88250888
75Abnormality of the carotid arteries (HP:0005344)1.88145191
76Type I transferrin isoform profile (HP:0003642)1.87985024
77Abnormality of the lower motor neuron (HP:0002366)1.87328045
78Abnormality of abdominal situs (HP:0011620)1.82016063
79Abdominal situs inversus (HP:0003363)1.82016063
80Abnormality of the renal medulla (HP:0100957)1.81842953
81Oculomotor apraxia (HP:0000657)1.80831468
82Decreased electroretinogram (ERG) amplitude (HP:0000654)1.80347996
83Generalized hypopigmentation of hair (HP:0011358)1.79151281
84Hematochezia (HP:0002573)1.79051225
85Preaxial hand polydactyly (HP:0001177)1.79005447
86Absent thumb (HP:0009777)1.73455186
87Hemivertebrae (HP:0002937)1.72762488
88Confusion (HP:0001289)1.70523006
89Atrophy/Degeneration involving motor neurons (HP:0007373)1.69581888
90Long nose (HP:0003189)1.68448791
91Tubular atrophy (HP:0000092)1.67250275
92Impaired proprioception (HP:0010831)1.67193842
93Abnormality of DNA repair (HP:0003254)1.65998717
94Ectropion (HP:0000656)1.65343608
95Menstrual irregularities (HP:0000858)1.64502631
96Keratoconus (HP:0000563)1.64446147
97Increased corneal curvature (HP:0100692)1.64446147
98Abnormality of the renal cortex (HP:0011035)1.64277179
99Methylmalonic aciduria (HP:0012120)1.63952362
100Gonadotropin excess (HP:0000837)1.63828792

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAF16.70536230
2FRK5.12773579
3NTRK14.12716196
4EIF2AK33.53706064
5TIE13.25277452
6NTRK22.86702056
7EPHA42.69002656
8WNK32.19843177
9MAP4K22.15263834
10STK392.12043369
11FGFR21.79137791
12OXSR11.74538902
13BRSK21.72545764
14ZAK1.69212354
15BMPR1B1.67219387
16ARAF1.57334593
17KSR21.50123657
18TSSK61.46891687
19MAP3K131.45477202
20LIMK11.34413426
21PDK21.34363177
22PLK21.30332547
23SRPK11.29920795
24WEE11.28722948
25MAP3K21.26369107
26NTRK31.24264916
27BCKDK1.22426103
28RAF11.21357203
29PAK31.19858057
30PRKCE1.19838424
31PBK1.18861851
32MAP3K91.17082902
33KSR11.14782754
34PLK31.10732536
35GRK11.10438417
36EIF2AK11.09384957
37ADRBK21.07665036
38STK111.05224486
39ZAP701.04502761
40MKNK21.03617589
41NUAK11.02852427
42TRIM281.00755527
43BUB10.99196582
44CDK30.94484877
45PLK40.93809321
46MKNK10.92978386
47PINK10.92033075
48EIF2AK20.78362801
49MST40.77536756
50MAPK130.75501935
51PIK3CG0.68717345
52ACVR1B0.65121957
53MAP3K120.63574282
54PRKAA10.63039221
55TNIK0.61165735
56PRKD10.60135589
57PLK10.59501199
58CDK80.59154802
59BRSK10.55995912
60TAOK30.55893662
61ERBB40.53765651
62OBSCN0.53700513
63STK30.53219214
64MOS0.52494254
65INSRR0.49311846
66MAP3K10.47193635
67CDC42BPA0.46743135
68TTK0.46477093
69NEK10.44514268
70VRK10.42733504
71PRKG10.42307346
72MAPK120.40802866
73CCNB10.40629849
74MAP2K10.39919499
75TGFBR10.38646335
76TYK20.37755640
77ERBB30.37490544
78JAK20.36920244
79TEC0.36633839
80MYLK0.36548339
81CSNK1A10.35906972
82AKT10.35280857
83MET0.34292278
84ATM0.33336125
85ABL10.32285361
86STK160.31916004
87AURKB0.30138068
88TNK20.28817672
89ADRBK10.28202368
90RPS6KB10.27238196
91SIK30.27040470
92IGF1R0.24793266
93ATR0.24627228
94EGFR0.23577293
95CAMK2A0.23415554
96ILK0.23408325
97MAPKAPK50.21949479
98PRKCQ0.21404948
99KIT0.20907784
100PTK2B0.18784702

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal transcription factors_Homo sapiens_hsa030224.18808000
2Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.17735760
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.03893582
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.03298427
5Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.82839675
6Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.77833607
7Selenocompound metabolism_Homo sapiens_hsa004502.77513112
8Propanoate metabolism_Homo sapiens_hsa006402.56616215
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.56171518
10Homologous recombination_Homo sapiens_hsa034402.50648687
11Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.17967109
12Primary bile acid biosynthesis_Homo sapiens_hsa001202.13147019
13Tryptophan metabolism_Homo sapiens_hsa003802.12986350
14ABC transporters_Homo sapiens_hsa020102.07262585
15Protein export_Homo sapiens_hsa030601.83038498
16Sulfur metabolism_Homo sapiens_hsa009201.71281242
17Non-homologous end-joining_Homo sapiens_hsa034501.67448066
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.56856003
19Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.54567855
20Linoleic acid metabolism_Homo sapiens_hsa005911.52456325
21Regulation of autophagy_Homo sapiens_hsa041401.50669269
22Histidine metabolism_Homo sapiens_hsa003401.48908986
23Chemical carcinogenesis_Homo sapiens_hsa052041.41676898
24Fanconi anemia pathway_Homo sapiens_hsa034601.39550203
25Pyruvate metabolism_Homo sapiens_hsa006201.30361632
26Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.28855175
27Mismatch repair_Homo sapiens_hsa034301.25606351
28Proteasome_Homo sapiens_hsa030501.24709239
29Butanoate metabolism_Homo sapiens_hsa006501.20310491
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18632344
31Phototransduction_Homo sapiens_hsa047441.14069060
32Parkinsons disease_Homo sapiens_hsa050121.13884241
33Nucleotide excision repair_Homo sapiens_hsa034201.13284654
34Inositol phosphate metabolism_Homo sapiens_hsa005621.10125984
35Fat digestion and absorption_Homo sapiens_hsa049751.07996915
36Fatty acid degradation_Homo sapiens_hsa000711.02436086
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.00044622
38Vitamin B6 metabolism_Homo sapiens_hsa007500.98743005
39Glutathione metabolism_Homo sapiens_hsa004800.96096608
40Thyroid hormone synthesis_Homo sapiens_hsa049180.95537515
41Oxidative phosphorylation_Homo sapiens_hsa001900.95238992
42Olfactory transduction_Homo sapiens_hsa047400.93272755
43ECM-receptor interaction_Homo sapiens_hsa045120.92450488
44beta-Alanine metabolism_Homo sapiens_hsa004100.90488890
45RNA degradation_Homo sapiens_hsa030180.90456554
46TGF-beta signaling pathway_Homo sapiens_hsa043500.90353111
47Steroid hormone biosynthesis_Homo sapiens_hsa001400.88907533
48Lysine degradation_Homo sapiens_hsa003100.88221249
49Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.88211912
50Vitamin digestion and absorption_Homo sapiens_hsa049770.87970873
51Caffeine metabolism_Homo sapiens_hsa002320.87667706
52Purine metabolism_Homo sapiens_hsa002300.86593363
53Huntingtons disease_Homo sapiens_hsa050160.83444182
54Dorso-ventral axis formation_Homo sapiens_hsa043200.83198629
55Long-term depression_Homo sapiens_hsa047300.80090379
56Ether lipid metabolism_Homo sapiens_hsa005650.79020750
57Retinol metabolism_Homo sapiens_hsa008300.77037219
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75435252
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75248806
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74701454
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71765185
62Serotonergic synapse_Homo sapiens_hsa047260.71713169
63Estrogen signaling pathway_Homo sapiens_hsa049150.69773028
64Arachidonic acid metabolism_Homo sapiens_hsa005900.68453517
65Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.65598703
66Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.63628429
67Mineral absorption_Homo sapiens_hsa049780.61050548
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60143528
69Sphingolipid metabolism_Homo sapiens_hsa006000.57860911
70Fatty acid elongation_Homo sapiens_hsa000620.57074701
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.56673357
72Taste transduction_Homo sapiens_hsa047420.50983780
73Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.50768794
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50725270
75Nitrogen metabolism_Homo sapiens_hsa009100.50219158
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.49828545
77Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48308041
78Fatty acid metabolism_Homo sapiens_hsa012120.45390516
79RNA transport_Homo sapiens_hsa030130.44379201
80Glycerolipid metabolism_Homo sapiens_hsa005610.44090289
81Steroid biosynthesis_Homo sapiens_hsa001000.43685140
82Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43643461
83Alzheimers disease_Homo sapiens_hsa050100.42682566
84p53 signaling pathway_Homo sapiens_hsa041150.42414465
85mRNA surveillance pathway_Homo sapiens_hsa030150.42217923
86RNA polymerase_Homo sapiens_hsa030200.41889744
87Peroxisome_Homo sapiens_hsa041460.41768379
88Salivary secretion_Homo sapiens_hsa049700.41457113
89Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.41404155
90Morphine addiction_Homo sapiens_hsa050320.40515119
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.40347234
92Metabolic pathways_Homo sapiens_hsa011000.37983341
93Asthma_Homo sapiens_hsa053100.37665372
94PI3K-Akt signaling pathway_Homo sapiens_hsa041510.35982267
95Dilated cardiomyopathy_Homo sapiens_hsa054140.33592473
96Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.33078845
97Adherens junction_Homo sapiens_hsa045200.32783150
98PPAR signaling pathway_Homo sapiens_hsa033200.31776632
99Arginine and proline metabolism_Homo sapiens_hsa003300.30838751
100Glioma_Homo sapiens_hsa052140.27746747

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »