GSPT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)5.30437911
2nuclear pore complex assembly (GO:0051292)5.27702849
3folic acid-containing compound biosynthetic process (GO:0009396)5.01016886
4DNA unwinding involved in DNA replication (GO:0006268)4.99899227
5protein localization to kinetochore (GO:0034501)4.47929412
6mitotic nuclear envelope disassembly (GO:0007077)4.43438071
7membrane disassembly (GO:0030397)4.19856439
8nuclear envelope disassembly (GO:0051081)4.19856439
9mitotic sister chromatid cohesion (GO:0007064)3.97608725
10heterochromatin organization (GO:0070828)3.92430382
11regulation of histone H3-K27 methylation (GO:0061085)3.92228739
12formation of translation preinitiation complex (GO:0001731)3.91128631
13regulation of translational fidelity (GO:0006450)3.88641735
14pore complex assembly (GO:0046931)3.88429143
15regulation of translational termination (GO:0006449)3.83485082
16IMP biosynthetic process (GO:0006188)3.76529689
17nucleobase biosynthetic process (GO:0046112)3.76352276
18pre-miRNA processing (GO:0031054)3.75372493
19ribosome assembly (GO:0042255)3.69209714
20protein localization to chromosome, centromeric region (GO:0071459)3.67713905
21regulation of spindle organization (GO:0090224)3.65649115
22negative regulation of DNA repair (GO:0045738)3.65473921
23protein export from nucleus (GO:0006611)3.64783893
24regulation of RNA export from nucleus (GO:0046831)3.56758054
25protoporphyrinogen IX metabolic process (GO:0046501)3.56202903
26DNA replication initiation (GO:0006270)3.53380408
27DNA duplex unwinding (GO:0032508)3.50384953
28DNA geometric change (GO:0032392)3.48096752
29hepatocyte apoptotic process (GO:0097284)3.46783633
30mitotic metaphase plate congression (GO:0007080)3.42688718
31IMP metabolic process (GO:0046040)3.41081248
32nuclear envelope organization (GO:0006998)3.40557407
33positive regulation of chromosome segregation (GO:0051984)3.37824952
34regulation of mitotic spindle organization (GO:0060236)3.37628923
35mitotic chromosome condensation (GO:0007076)3.35760504
36DNA strand elongation involved in DNA replication (GO:0006271)3.35252998
37regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.35047397
38folic acid metabolic process (GO:0046655)3.34039489
39DNA replication-dependent nucleosome assembly (GO:0006335)3.32479914
40DNA replication-dependent nucleosome organization (GO:0034723)3.32479914
41purine nucleobase biosynthetic process (GO:0009113)3.29189501
42tetrahydrofolate metabolic process (GO:0046653)3.27608783
43sister chromatid segregation (GO:0000819)3.25939687
44mRNA stabilization (GO:0048255)3.22667012
45RNA stabilization (GO:0043489)3.22667012
46embryonic process involved in female pregnancy (GO:0060136)3.19948288
47cellular protein complex localization (GO:0034629)3.18903905
48COPI coating of Golgi vesicle (GO:0048205)3.18341680
49Golgi transport vesicle coating (GO:0048200)3.18341680
50DNA strand elongation (GO:0022616)3.14088070
51histone H3-K36 demethylation (GO:0070544)3.13391783
52chromatin assembly (GO:0031497)3.12131287
53dosage compensation (GO:0007549)3.11916421
54regulation of posttranscriptional gene silencing (GO:0060147)3.10672358
55regulation of gene silencing by miRNA (GO:0060964)3.10672358
56regulation of gene silencing by RNA (GO:0060966)3.10672358
57mitotic sister chromatid segregation (GO:0000070)3.09720053
58maturation of SSU-rRNA (GO:0030490)3.04795093
59negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.04757091
60regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.01157107
61regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.00754314
62protein complex localization (GO:0031503)2.96407786
63regulation of sister chromatid cohesion (GO:0007063)2.94153163
64histone H2A monoubiquitination (GO:0035518)2.92509900
65chaperone-mediated protein complex assembly (GO:0051131)2.91675232
66metaphase plate congression (GO:0051310)2.91548438
67glycine metabolic process (GO:0006544)2.90314517
683-UTR-mediated mRNA stabilization (GO:0070935)2.90010756
69negative regulation of histone methylation (GO:0031061)2.88691712
70positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.86886713
71positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.86886713
72positive regulation of mitotic sister chromatid separation (GO:1901970)2.86886713
73DNA replication checkpoint (GO:0000076)2.86494281
74cellular hyperosmotic response (GO:0071474)2.85622027
75regulation of histone H3-K9 methylation (GO:0051570)2.85041866
76folic acid-containing compound metabolic process (GO:0006760)2.82280851
77negative regulation of RNA splicing (GO:0033119)2.81696477
78positive regulation of SMAD protein import into nucleus (GO:0060391)2.81144721
79NLS-bearing protein import into nucleus (GO:0006607)2.79971610
80regulation of nucleobase-containing compound transport (GO:0032239)2.78170825
81chromatin assembly or disassembly (GO:0006333)2.76384965
82very-low-density lipoprotein particle assembly (GO:0034379)2.75282005
83protein localization to chromosome (GO:0034502)2.75263235
84DNA conformation change (GO:0071103)2.74400100
85ribosome biogenesis (GO:0042254)2.73384499
86positive regulation of cellular response to insulin stimulus (GO:1900078)2.72564209
87chromosome condensation (GO:0030261)2.72549589
88focal adhesion assembly (GO:0048041)2.71947030
89cell-substrate adherens junction assembly (GO:0007045)2.71947030
90negative regulation of mRNA metabolic process (GO:1903312)2.71301243
91histone-serine phosphorylation (GO:0035404)2.70927609
92pteridine-containing compound biosynthetic process (GO:0042559)2.70330576
93cytoplasmic mRNA processing body assembly (GO:0033962)2.70141758
94kinetochore organization (GO:0051383)2.68810776
95negative regulation of mRNA processing (GO:0050686)2.68783368
96telomere maintenance via semi-conservative replication (GO:0032201)2.68095565
97regulation of centrosome cycle (GO:0046605)2.66225126
98regulation of chromosome segregation (GO:0051983)2.65033864
99iron ion import (GO:0097286)2.64927978
100positive regulation of insulin receptor signaling pathway (GO:0046628)2.62352025
101positive regulation of protein import into nucleus, translocation (GO:0033160)2.60591473
102translational initiation (GO:0006413)2.59713972
103nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.59095758
104mitotic G1 DNA damage checkpoint (GO:0031571)2.58858708
105L-serine metabolic process (GO:0006563)2.58521238
106glucocorticoid receptor signaling pathway (GO:0042921)2.58419048
107spliceosomal tri-snRNP complex assembly (GO:0000244)2.58087099
108DNA replication-independent nucleosome organization (GO:0034724)2.57746479
109DNA replication-independent nucleosome assembly (GO:0006336)2.57746479
110attachment of spindle microtubules to kinetochore (GO:0008608)2.57595068
111histone phosphorylation (GO:0016572)2.57291248
112alternative mRNA splicing, via spliceosome (GO:0000380)2.56917442
113mRNA transport (GO:0051028)2.56294770
114mitotic recombination (GO:0006312)2.56016358
115regulation of mRNA stability (GO:0043488)2.55583280
116protein localization to microtubule (GO:0035372)2.55497716
117chromatin remodeling at centromere (GO:0031055)2.55367889
118COPII vesicle coating (GO:0048208)2.55289227
119peptidyl-threonine modification (GO:0018210)2.55247075
120DNA topological change (GO:0006265)2.54338637
121serine family amino acid biosynthetic process (GO:0009070)2.53900246
122cellular response to epidermal growth factor stimulus (GO:0071364)2.53833406
123establishment of chromosome localization (GO:0051303)2.52852231
124peptidyl-threonine phosphorylation (GO:0018107)2.50903475
125hypotonic response (GO:0006971)2.50664928
126negative regulation of necroptotic process (GO:0060546)2.50220745
127ribosomal large subunit biogenesis (GO:0042273)2.50027354
128regulation of RNA stability (GO:0043487)2.49690018
129proline biosynthetic process (GO:0006561)2.49574390
130corticosteroid receptor signaling pathway (GO:0031958)2.49278452
131response to epidermal growth factor (GO:0070849)2.49162142
132translesion synthesis (GO:0019985)2.48961895
133histone H3-K9 demethylation (GO:0033169)2.48709396
134adherens junction assembly (GO:0034333)2.48343654
135one-carbon metabolic process (GO:0006730)2.47875107
136DNA packaging (GO:0006323)2.47365000
137N-terminal protein amino acid acetylation (GO:0006474)2.44980888
138cell-substrate junction assembly (GO:0007044)2.44028030
139histone H2B ubiquitination (GO:0033523)2.43907593
140positive regulation of receptor recycling (GO:0001921)2.35758898
141negative regulation of histone modification (GO:0031057)2.35158235
142negative regulation of fibroblast apoptotic process (GO:2000270)2.33733266
143positive regulation of keratinocyte differentiation (GO:0045618)2.33467568
144regulation of centriole replication (GO:0046599)2.32011366
145phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.31712490
146regulation of NFAT protein import into nucleus (GO:0051532)2.31129973

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.40749347
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.54695306
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.74174958
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.54028977
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.32563545
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.27282893
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.80821377
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.71920597
9AR_21909140_ChIP-Seq_LNCAP_Human2.60810961
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.53662180
11MYC_22102868_ChIP-Seq_BL_Human2.50863797
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.30160014
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.14957299
14* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.03742971
15E2F1_21310950_ChIP-Seq_MCF-7_Human2.02768143
16GATA1_22025678_ChIP-Seq_K562_Human2.01903796
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.97540747
18PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.93113318
19XRN2_22483619_ChIP-Seq_HELA_Human1.89210089
20MYCN_18555785_ChIP-Seq_MESCs_Mouse1.76701018
21CREB1_15753290_ChIP-ChIP_HEK293T_Human1.75065318
22FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.69289781
23TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.67913048
24STAT3_1855785_ChIP-Seq_MESCs_Mouse1.62329198
25ZNF263_19887448_ChIP-Seq_K562_Human1.56596346
26* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.54660484
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.54556241
28* ETS1_20019798_ChIP-Seq_JURKAT_Human1.53579374
29SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.49425353
30POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.49153353
31* KDM5A_27292631_Chip-Seq_BREAST_Human1.48446944
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.46573534
33* EST1_17652178_ChIP-ChIP_JURKAT_Human1.46169933
34POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.44870678
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.43381883
36KLF4_18555785_ChIP-Seq_MESCs_Mouse1.42987291
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39785867
38DCP1A_22483619_ChIP-Seq_HELA_Human1.39716859
39TP63_17297297_ChIP-ChIP_HaCaT_Human1.37929409
40SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.36987965
41ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.36467368
42CLOCK_20551151_ChIP-Seq_293T_Human1.35771096
43E2F1_18555785_ChIP-Seq_MESCs_Mouse1.35560490
44TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.34715296
45VDR_23849224_ChIP-Seq_CD4+_Human1.34582440
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.33798970
47ESR1_15608294_ChIP-ChIP_MCF-7_Human1.30444002
48VDR_21846776_ChIP-Seq_THP-1_Human1.30283278
49* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28572997
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.27058512
51* GABP_19822575_ChIP-Seq_HepG2_Human1.27005179
52TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.25222062
53CIITA_25753668_ChIP-Seq_RAJI_Human1.25183449
54* TTF2_22483619_ChIP-Seq_HELA_Human1.25142548
55DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.24057954
56TFEB_21752829_ChIP-Seq_HELA_Human1.23788877
57DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21374199
58* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.21180198
59FOXP3_21729870_ChIP-Seq_TREG_Human1.20754580
60GABP_17652178_ChIP-ChIP_JURKAT_Human1.20108362
61NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.20034924
62WT1_19549856_ChIP-ChIP_CCG9911_Human1.18982343
63ATF3_27146783_Chip-Seq_COLON_Human1.18639545
64P300_27058665_Chip-Seq_ZR-75-30cells_Human1.18021842
65SALL1_21062744_ChIP-ChIP_HESCs_Human1.17879719
66* CHD1_26751641_Chip-Seq_LNCaP_Human1.17355618
67KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16424043
68ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.16118333
69NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.15959988
70KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.15322654
71TCF3_18692474_ChIP-Seq_MEFs_Mouse1.15224232
72FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.14481593
73* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.13795785
74HIF1A_21447827_ChIP-Seq_MCF-7_Human1.13711137
75* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.12795714
76* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.12795714
77CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.11562473
78NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.11374230
79ELK1_19687146_ChIP-ChIP_HELA_Human1.09028152
80TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08726959
81* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08493386
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08435881
83SALL4_18804426_ChIP-ChIP_XEN_Mouse1.08081172
84SOX2_27498859_Chip-Seq_STOMACH_Mouse1.06234246
85* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05882885
86ERG_20887958_ChIP-Seq_HPC-7_Mouse1.05138728
87GATA1_22383799_ChIP-Seq_G1ME_Mouse1.04687001
88* TCF7_22412390_ChIP-Seq_EML_Mouse1.04493119
89SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.04201947
90RACK7_27058665_Chip-Seq_MCF-7_Human1.03418076
91JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.02900635
92GATA1_19941826_ChIP-Seq_K562_Human1.02611237
93* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.01992273
94* ELK3_25401928_ChIP-Seq_HUVEC_Human1.01948375
95* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01890379
96* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01858066
97YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01842804
98ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01356080
99SCL_19346495_ChIP-Seq_HPC-7_Human1.01236737
100TP63_19390658_ChIP-ChIP_HaCaT_Human1.01081926
101KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.00857172
102* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00779613
103STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.00753221
104* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00423877
105ESR1_20079471_ChIP-ChIP_T-47D_Human1.00123712
106STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99824218
107PPARA_22158963_ChIP-Seq_LIVER_Mouse0.99336569
108* MYB_26560356_Chip-Seq_TH1_Human0.99332773
109GATA4_21415370_ChIP-Seq_HL-1_Mouse0.98113376
110PKCTHETA_26484144_Chip-Seq_BREAST_Human0.98028215
111HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97780226
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97537667
113MYB_21317192_ChIP-Seq_ERMYB_Mouse0.97370979
114GATA6_25053715_ChIP-Seq_YYC3_Human0.96947701
115* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96183316
116SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.95281834
117SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.95090603
118NANOG_21062744_ChIP-ChIP_HESCs_Human0.94552146
119NCOR1_26117541_ChIP-Seq_K562_Human0.94376847
120PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.93884234
121* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.93313969
122ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.92838112
123UTX_26944678_Chip-Seq_JUKART_Human0.92329993
124KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.92176168
125KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.92176168
126KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.92176168
127* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.91678761
128FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.90934003
129MAF_26560356_Chip-Seq_TH1_Human0.90913227
130* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.89964409
131EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.89938718
132* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.89709184
133TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89246109
134SOX2_18555785_ChIP-Seq_MESCs_Mouse0.87204290
135HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.86645198
136* KDM2B_26808549_Chip-Seq_DND41_Human0.86499805

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.48332060
2MP0003705_abnormal_hypodermis_morpholog3.46593255
3MP0003693_abnormal_embryo_hatching3.42889321
4MP0004957_abnormal_blastocyst_morpholog3.20520529
5MP0003111_abnormal_nucleus_morphology3.05422856
6MP0005451_abnormal_body_composition3.01291579
7MP0010094_abnormal_chromosome_stability2.96281164
8MP0003656_abnormal_erythrocyte_physiolo2.93356324
9MP0003077_abnormal_cell_cycle2.67403414
10MP0008260_abnormal_autophagy2.61009237
11MP0008057_abnormal_DNA_replication2.49990199
12MP0005076_abnormal_cell_differentiation2.46811122
13MP0001730_embryonic_growth_arrest2.31222172
14MP0010307_abnormal_tumor_latency2.19097801
15MP0004233_abnormal_muscle_weight2.18307890
16MP0002009_preneoplasia2.00316735
17MP0000350_abnormal_cell_proliferation1.98329453
18MP0002396_abnormal_hematopoietic_system1.89464856
19MP0003806_abnormal_nucleotide_metabolis1.85321389
20MP0003123_paternal_imprinting1.85295190
21MP0004197_abnormal_fetal_growth/weight/1.84106708
22MP0008007_abnormal_cellular_replicative1.82937552
23MP0001672_abnormal_embryogenesis/_devel1.79453189
24MP0005380_embryogenesis_phenotype1.79453189
25MP0009053_abnormal_anal_canal1.73833105
26MP0003566_abnormal_cell_adhesion1.71494128
27MP0003984_embryonic_growth_retardation1.71357864
28MP0002088_abnormal_embryonic_growth/wei1.70045664
29MP0002086_abnormal_extraembryonic_tissu1.68404776
30MP0002166_altered_tumor_susceptibility1.68260085
31MP0001697_abnormal_embryo_size1.67627210
32MP0008932_abnormal_embryonic_tissue1.58721651
33MP0002084_abnormal_developmental_patter1.57876063
34MP0010234_abnormal_vibrissa_follicle1.53898760
35MP0010030_abnormal_orbit_morphology1.49341069
36MP0002080_prenatal_lethality1.49298749
37MP0003567_abnormal_fetal_cardiomyocyte1.48645128
38MP0008438_abnormal_cutaneous_collagen1.48391016
39MP0002877_abnormal_melanocyte_morpholog1.47391024
40MP0003763_abnormal_thymus_physiology1.45805147
41MP0002085_abnormal_embryonic_tissue1.45581536
42MP0005023_abnormal_wound_healing1.40109719
43MP0002796_impaired_skin_barrier1.39742251
44MP0003300_gastrointestinal_ulcer1.36596215
45MP0004185_abnormal_adipocyte_glucose1.36170706
46MP0000537_abnormal_urethra_morphology1.33891384
47MP0003941_abnormal_skin_development1.32554372
48MP0000733_abnormal_muscle_development1.32543328
49MP0003950_abnormal_plasma_membrane1.32029422
50MP0000490_abnormal_crypts_of1.29190349
51MP0009672_abnormal_birth_weight1.27537848
52MP0004808_abnormal_hematopoietic_stem1.26955189
53MP0006054_spinal_hemorrhage1.26861378
54MP0008058_abnormal_DNA_repair1.25313929
55MP0005409_darkened_coat_color1.24616875
56MP0004381_abnormal_hair_follicle1.23114779
57MP0001915_intracranial_hemorrhage1.17583447
58MP0002006_tumorigenesis1.17019625
59MP0003890_abnormal_embryonic-extraembry1.14541524
60MP0002019_abnormal_tumor_incidence1.11469626
61MP0001661_extended_life_span1.09595899
62MP0001849_ear_inflammation1.08376044
63MP0009278_abnormal_bone_marrow1.08055852
64MP0005397_hematopoietic_system_phenotyp1.07793263
65MP0001545_abnormal_hematopoietic_system1.07793263
66MP0000569_abnormal_digit_pigmentation1.04334945
67MP0001293_anophthalmia1.03778057
68MP0005408_hypopigmentation1.03041279
69MP0000313_abnormal_cell_death1.01043212
70MP0002139_abnormal_hepatobiliary_system0.98018094
71MP0009703_decreased_birth_body0.97598613
72MP0005360_urolithiasis0.96978119
73MP0004264_abnormal_extraembryonic_tissu0.95082702
74MP0002092_abnormal_eye_morphology0.93751172
75MP0003303_peritoneal_inflammation0.92467922
76MP0000428_abnormal_craniofacial_morphol0.91713849
77MP0009697_abnormal_copulation0.89138931
78MP0003221_abnormal_cardiomyocyte_apopto0.88000416
79MP0004087_abnormal_muscle_fiber0.87442125
80MP0002697_abnormal_eye_size0.87420478
81MP0003453_abnormal_keratinocyte_physiol0.87300278
82MP0009333_abnormal_splenocyte_physiolog0.85839145
83MP0004272_abnormal_basement_membrane0.85809747
84MP0002269_muscular_atrophy0.85716309
85MP0002111_abnormal_tail_morphology0.84671826
86MP0009840_abnormal_foam_cell0.84071959
87MP0005275_abnormal_skin_tensile0.82841051
88MP0000377_abnormal_hair_follicle0.81953906
89MP0000858_altered_metastatic_potential0.81868336
90MP0005666_abnormal_adipose_tissue0.81503083
91MP0003119_abnormal_digestive_system0.80648977
92MP0000598_abnormal_liver_morphology0.79945104
93MP0003115_abnormal_respiratory_system0.79130859
94MP0000759_abnormal_skeletal_muscle0.78031621
95MP0002925_abnormal_cardiovascular_devel0.77733162
96MP0003786_premature_aging0.75750617
97MP0010678_abnormal_skin_adnexa0.75253742
98MP0000477_abnormal_intestine_morphology0.74847153
99MP0000703_abnormal_thymus_morphology0.73677292
100MP0003448_altered_tumor_morphology0.73660659
101MP0005501_abnormal_skin_physiology0.73026079
102MP0003943_abnormal_hepatobiliary_system0.72440530
103MP0001243_abnormal_dermal_layer0.71462727
104MP0005621_abnormal_cell_physiology0.71395806
105MP0002060_abnormal_skin_morphology0.70991559
106MP0003937_abnormal_limbs/digits/tail_de0.70805734
107MP0001348_abnormal_lacrimal_gland0.70134929
108MP0000627_abnormal_mammary_gland0.69635212
109MP0001216_abnormal_epidermal_layer0.69088629
110MP0005085_abnormal_gallbladder_physiolo0.68864936
111MP0005375_adipose_tissue_phenotype0.67360967
112MP0003868_abnormal_feces_composition0.67287296
113MP0000003_abnormal_adipose_tissue0.66607227
114MP0000609_abnormal_liver_physiology0.66001352
115MP0008770_decreased_survivor_rate0.65693329
116MP0000432_abnormal_head_morphology0.65437383
117MP0005384_cellular_phenotype0.64112410
118MP0003091_abnormal_cell_migration0.63647109
119MP0000358_abnormal_cell_content/0.63326782
120MP0002722_abnormal_immune_system0.63224998
121MP0002089_abnormal_postnatal_growth/wei0.63130633
122MP0006138_congestive_heart_failure0.62151645
123MP0009931_abnormal_skin_appearance0.61962116
124MP0003252_abnormal_bile_duct0.61301907
125MP0005623_abnormal_meninges_morphology0.60883951
126MP0010630_abnormal_cardiac_muscle0.60842830
127MP0002398_abnormal_bone_marrow0.60775085
128MP0004947_skin_inflammation0.60663820
129MP0009780_abnormal_chondrocyte_physiolo0.60537432
130MP0000383_abnormal_hair_follicle0.60446615
131MP0003121_genomic_imprinting0.60063196
132MP0000747_muscle_weakness0.58856050

Predicted human phenotypes

RankGene SetZ-score
1Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.90582301
2Protrusio acetabuli (HP:0003179)3.13461424
3Asymmetry of the thorax (HP:0001555)3.07977928
4Colon cancer (HP:0003003)2.98611287
5Ependymoma (HP:0002888)2.95238608
6Ankyloglossia (HP:0010296)2.90725906
7Selective tooth agenesis (HP:0001592)2.86099024
8Orthostatic hypotension (HP:0001278)2.85198098
9Papillary thyroid carcinoma (HP:0002895)2.81951411
10Deviation of the thumb (HP:0009603)2.78934616
11Dysmetric saccades (HP:0000641)2.70024340
12Proximal placement of thumb (HP:0009623)2.69796276
13Premature rupture of membranes (HP:0001788)2.59835441
14Abnormality of oral frenula (HP:0000190)2.58923451
15Spinal cord lesions (HP:0100561)2.54869830
16Syringomyelia (HP:0003396)2.54869830
17Rhabdomyosarcoma (HP:0002859)2.52878810
18Spastic diplegia (HP:0001264)2.51684837
19Ankle contracture (HP:0006466)2.46460222
20Deep philtrum (HP:0002002)2.45199592
21Rectal prolapse (HP:0002035)2.42830553
22Acute myeloid leukemia (HP:0004808)2.40227457
23Slow saccadic eye movements (HP:0000514)2.38557223
24Increased nuchal translucency (HP:0010880)2.38284308
25Birth length less than 3rd percentile (HP:0003561)2.35631274
26Biliary tract neoplasm (HP:0100574)2.34215866
27Medulloblastoma (HP:0002885)2.34126054
28Abnormality of the fingertips (HP:0001211)2.33680796
29Osteolytic defects of the hand bones (HP:0009699)2.32167714
30Osteolytic defects of the phalanges of the hand (HP:0009771)2.32167714
31Flat acetabular roof (HP:0003180)2.30045300
32Nephroblastoma (Wilms tumor) (HP:0002667)2.27249685
33Septate vagina (HP:0001153)2.27127174
34Shallow orbits (HP:0000586)2.26965008
35Increased density of long bones (HP:0006392)2.25595212
36Genu recurvatum (HP:0002816)2.24920671
37Abnormality of the astrocytes (HP:0100707)2.22056850
38Astrocytoma (HP:0009592)2.22056850
39Abnormal foot bone ossification (HP:0010675)2.21992063
40Insidious onset (HP:0003587)2.21845639
41Termporal pattern (HP:0011008)2.21845639
42Progressive muscle weakness (HP:0003323)2.20364574
43Volvulus (HP:0002580)2.19759198
44Dislocated radial head (HP:0003083)2.17766361
45Basal cell carcinoma (HP:0002671)2.16148386
46Multiple enchondromatosis (HP:0005701)2.15097015
47Cholecystitis (HP:0001082)2.14371303
48Abnormal gallbladder physiology (HP:0012438)2.14371303
49Poikilocytosis (HP:0004447)2.13473886
50Abnormality of the calcaneus (HP:0008364)2.12893842
51Deep venous thrombosis (HP:0002625)2.12006058
52Short 4th metacarpal (HP:0010044)2.11047915
53Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.11047915
54Gastrointestinal carcinoma (HP:0002672)2.10429492
55Malignant gastrointestinal tract tumors (HP:0006749)2.10429492
56Embryonal renal neoplasm (HP:0011794)2.10385906
57Leiomyosarcoma (HP:0100243)2.09535088
58Uterine leiomyosarcoma (HP:0002891)2.09535088
59Abnormality of the anterior horn cell (HP:0006802)2.09202495
60Degeneration of anterior horn cells (HP:0002398)2.09202495
61Back pain (HP:0003418)2.07137668
62Subacute progressive viral hepatitis (HP:0006572)2.06394211
63High pitched voice (HP:0001620)2.04954468
64Progressive external ophthalmoplegia (HP:0000590)2.03674774
65Chromsome breakage (HP:0040012)2.03057347
66Pseudobulbar signs (HP:0002200)2.01732974
67Resting tremor (HP:0002322)2.01651117
68Urethral obstruction (HP:0000796)2.00117585
69Pelvic girdle muscle weakness (HP:0003749)1.99920055
70Oral leukoplakia (HP:0002745)1.99596422
71Reticulocytopenia (HP:0001896)1.99417277
72Viral hepatitis (HP:0006562)1.96387551
73Neoplasm of striated muscle (HP:0009728)1.96112404
74Abnormality of the radial head (HP:0003995)1.95914559
75Atresia of the external auditory canal (HP:0000413)1.95450894
76Chromosomal breakage induced by crosslinking agents (HP:0003221)1.95387204
77Trismus (HP:0000211)1.95016900
78Abnormality of the left ventricular outflow tract (HP:0011103)1.94397791
79Subaortic stenosis (HP:0001682)1.94397791
80Squamous cell carcinoma (HP:0002860)1.94341813
81Acanthocytosis (HP:0001927)1.94121806
82Micronodular cirrhosis (HP:0001413)1.93381579
83Sandal gap (HP:0001852)1.92671335
84Cholelithiasis (HP:0001081)1.91726503
85Ulnar bowing (HP:0003031)1.90506543
86Transitional cell carcinoma of the bladder (HP:0006740)1.90356164
87Cerebral inclusion bodies (HP:0100314)1.89613902
88Abnormality of monocarboxylic acid metabolism (HP:0010996)1.89004469
89Breast hypoplasia (HP:0003187)1.88484028
90Mitral valve prolapse (HP:0001634)1.88453425
91Facial hemangioma (HP:0000329)1.88268466
92Cerebral aneurysm (HP:0004944)1.86852878
93Macroorchidism (HP:0000053)1.86190193
94Bladder carcinoma (HP:0002862)1.85313916
95Bladder neoplasm (HP:0009725)1.85313916
96Renal cell carcinoma (HP:0005584)1.85090314
97Thyroid carcinoma (HP:0002890)1.84401249
98Abnormality of the peritoneum (HP:0002585)1.84369944
99Arterial tortuosity (HP:0005116)1.82637132
100Polycythemia (HP:0001901)1.82079077
101Disproportionate tall stature (HP:0001519)1.81882482
102Achilles tendon contracture (HP:0001771)1.81773847
103Hyperacusis (HP:0010780)1.81647159
104Adenoma sebaceum (HP:0009720)1.81619028
105Angiofibromas (HP:0010615)1.81619028
106Abnormality of the Achilles tendon (HP:0005109)1.81275682
107Metaphyseal cupping (HP:0003021)1.80641246
108Fatigue (HP:0012378)1.79614823
109Neoplasm of the oral cavity (HP:0100649)1.79338790
110Glioma (HP:0009733)1.78587347
111Abnormality of pyrimidine metabolism (HP:0004353)1.77952448
112Distal lower limb amyotrophy (HP:0008944)1.77425256
113Missing ribs (HP:0000921)1.77379980
114Abnormality of carpal bone ossification (HP:0006257)1.76254971
115Uterine neoplasm (HP:0010784)1.76109763
116Increased mean platelet volume (HP:0011877)1.75835362
117Abnormality of the 4th metacarpal (HP:0010012)1.75217883
118Advanced eruption of teeth (HP:0006288)1.74876622
119Limited elbow extension (HP:0001377)1.74151401
120T lymphocytopenia (HP:0005403)1.73688468
121Relative macrocephaly (HP:0004482)1.73269488
122Overlapping toe (HP:0001845)1.72908454
123Agnosia (HP:0010524)1.71383737
124Low anterior hairline (HP:0000294)1.70875136
125Prominent nose (HP:0000448)1.70614037
126Abnormality of the distal phalanx of the thumb (HP:0009617)1.69878265
127Neoplasm of the pancreas (HP:0002894)1.69277970
128Fibroma (HP:0010614)1.69236225
129Cortical dysplasia (HP:0002539)1.68515177
130Skin tags (HP:0010609)1.68359202
131Cutaneous melanoma (HP:0012056)1.68322467
132Fibrous tissue neoplasm (HP:0012316)1.68050518
133Right ventricular cardiomyopathy (HP:0011663)1.67328562
134Long eyelashes (HP:0000527)1.67309984
135Increased connective tissue (HP:0009025)1.67299035
136Abnormality of skeletal muscle fiber size (HP:0012084)1.66000263
137Germ cell neoplasia (HP:0100728)1.65501552
138Microglossia (HP:0000171)1.65414761
139Abnormality of reticulocytes (HP:0004312)1.65322452
140Cervical subluxation (HP:0003308)1.65231061
141Vertebral arch anomaly (HP:0008438)1.64914040
142Centrally nucleated skeletal muscle fibers (HP:0003687)1.64398525
143Intestinal polyp (HP:0005266)1.64180186
144Abnormal ossification of hand bones (HP:0005921)1.63532240
145Abnormal gallbladder morphology (HP:0012437)1.63195945
146Impulsivity (HP:0100710)1.62564025
147Cutis marmorata (HP:0000965)1.62120606
148Heterotopia (HP:0002282)1.61163905
149Intestinal polyposis (HP:0200008)1.60720503
150Abnormality of the distal phalanges of the toes (HP:0010182)1.60698736
151Myocardial infarction (HP:0001658)1.60583911
152Reticulocytosis (HP:0001923)1.60326142
153Hallux valgus (HP:0001822)1.59829349
154Peritonitis (HP:0002586)1.59785592
155Broad thumb (HP:0011304)1.59636652
156Blepharitis (HP:0000498)1.58780772
157Vertebral clefting (HP:0008428)1.58506669
158Bowel diverticulosis (HP:0005222)1.57994745
159Ovarian neoplasm (HP:0100615)1.57887362
160Thrombocytosis (HP:0001894)1.57765966
161Abnormal platelet volume (HP:0011876)1.57432970
162Preauricular skin tag (HP:0000384)1.57355789
163Abnormal biliary tract morphology (HP:0012440)1.57211671
164Broad palm (HP:0001169)1.56860075
165Dilatation of the ascending aorta (HP:0005111)1.56748551
166Sparse lateral eyebrow (HP:0005338)1.56598888
167Cafe-au-lait spot (HP:0000957)1.56285989
168Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.56089807
169Deviation of the hallux (HP:0010051)1.55807829
170Renal duplication (HP:0000075)1.55804019

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.56595964
2CDK123.18789359
3SMG13.17458043
4PKN23.15328554
5EEF2K2.87889109
6TRIB32.74585395
7WEE12.68088527
8NEK22.59639543
9MAP3K102.52017717
10BUB12.12614708
11SCYL21.97224542
12TTK1.95740030
13NEK11.89247095
14EIF2AK11.82177393
15LATS11.76219078
16PRPF4B1.73877440
17ALK1.71727879
18RPS6KA41.70866930
19STK101.70411083
20NME21.66173773
21RPS6KB21.63661740
22TSSK61.60911953
23CDK41.58682038
24MAP3K81.57257188
25CDK61.55846464
26EPHA21.53960567
27IRAK31.50967602
28KSR21.49723667
29WNK11.46449336
30PASK1.42704970
31CLK11.41527745
32STK31.36753963
33MKNK11.33996801
34MAP3K21.32918406
35LRRK21.29918013
36TESK21.29534853
37CDK71.27718130
38DMPK1.27041779
39MAP3K131.26773507
40ACVR1B1.25895569
41TTN1.24452970
42PLK11.21576893
43MTOR1.21290996
44ATR1.20189319
45PTK61.20065589
46AURKB1.19770859
47PAK41.19358245
48TRPM71.17813609
49TGFBR11.16873902
50CHEK11.15300870
51BRSK21.13463971
52FLT31.12777308
53SRPK11.07497037
54BRD41.07476152
55TAF11.07268480
56MAP3K141.06738991
57KSR11.05812815
58MAP2K31.03461659
59PAK21.03279721
60BMX1.03152965
61YES11.01216317
62PLK30.98020469
63PDGFRA0.96723990
64SGK30.93083077
65CAMK1G0.92040331
66STK40.88583962
67MET0.88187109
68RAF10.87727759
69TAOK20.87563319
70ERN10.86192456
71MAP3K10.86091540
72LATS20.85282856
73FGFR10.83726370
74MKNK20.83594548
75ATM0.83110271
76CDK20.81942364
77CHEK20.81379547
78DYRK30.78893161
79MELK0.78540739
80MAP4K10.78327818
81NEK90.77134766
82FGR0.76673907
83CDK80.76640655
84PIM10.76545117
85EIF2AK30.76169455
86SIK10.71314858
87GRK60.71306469
88MST1R0.70822747
89PLK40.69934125
90RIPK10.69402557
91ICK0.68201956
92JAK30.64889214
93MAP3K30.63704782
94TESK10.63324129
95NEK60.62480987
96AURKA0.60494040
97CDK90.58985577
98AKT30.58696882
99FGFR40.57089168
100CAMK1D0.57027578
101SGK20.56847800
102TYRO30.54960891
103CDK10.54641327
104CSNK1E0.54505067
105CSNK2A20.52140075
106RET0.51053121
107MAP3K110.50922251
108MAP3K90.50683135
109DDR20.50146675
110RPS6KB10.49051787
111PAK10.48834723
112CSNK1D0.47970205
113MAPK110.47395355
114PDGFRB0.46724194
115EIF2AK20.46424127
116STK240.46045887
117AKT20.44848078
118ZAP700.44172496
119PRKDC0.41995759
120FGFR30.39175630
121PDPK10.38217183
122ERBB40.37226639
123MAP3K50.34972862
124PBK0.34616857
125PNCK0.34224381
126ILK0.34170396
127BRSK10.33790587
128TAOK10.33597550
129MAPK10.33080498
130RPS6KA10.32160045
131PTK20.31121589
132EGFR0.30878699
133MAPK140.30784493
134CSNK2A10.30435437
135CSF1R0.29893741

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.49797500
2One carbon pool by folate_Homo sapiens_hsa006703.33897723
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.05216506
4RNA transport_Homo sapiens_hsa030132.98235347
5Mismatch repair_Homo sapiens_hsa034302.75307177
6Spliceosome_Homo sapiens_hsa030402.48529984
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.43104383
8Cell cycle_Homo sapiens_hsa041102.37378400
9Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.91460438
10Base excision repair_Homo sapiens_hsa034101.83688978
11Selenocompound metabolism_Homo sapiens_hsa004501.83656916
12Nucleotide excision repair_Homo sapiens_hsa034201.72373796
13Nitrogen metabolism_Homo sapiens_hsa009101.61754118
14* mRNA surveillance pathway_Homo sapiens_hsa030151.58977136
15Cyanoamino acid metabolism_Homo sapiens_hsa004601.47352762
16p53 signaling pathway_Homo sapiens_hsa041151.43820502
17Biosynthesis of amino acids_Homo sapiens_hsa012301.37929961
18Homologous recombination_Homo sapiens_hsa034401.37477316
19Thyroid hormone signaling pathway_Homo sapiens_hsa049191.36309784
20Glioma_Homo sapiens_hsa052141.34626252
21B cell receptor signaling pathway_Homo sapiens_hsa046621.33777297
22Ribosome_Homo sapiens_hsa030101.32427711
23Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.27797269
24Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.25176370
25Small cell lung cancer_Homo sapiens_hsa052221.22219688
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.22022692
27Antigen processing and presentation_Homo sapiens_hsa046121.21437697
28MicroRNAs in cancer_Homo sapiens_hsa052061.20393216
29VEGF signaling pathway_Homo sapiens_hsa043701.20246520
30Cysteine and methionine metabolism_Homo sapiens_hsa002701.19459052
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.17687383
32Viral carcinogenesis_Homo sapiens_hsa052031.16574437
33RNA degradation_Homo sapiens_hsa030181.16541411
34Drug metabolism - other enzymes_Homo sapiens_hsa009831.16532583
35Longevity regulating pathway - mammal_Homo sapiens_hsa042111.15820745
36Prolactin signaling pathway_Homo sapiens_hsa049171.14337490
37FoxO signaling pathway_Homo sapiens_hsa040681.13626788
38ErbB signaling pathway_Homo sapiens_hsa040121.13330553
39Chronic myeloid leukemia_Homo sapiens_hsa052201.12902062
40Inositol phosphate metabolism_Homo sapiens_hsa005621.12542018
41Pyrimidine metabolism_Homo sapiens_hsa002401.10978232
42Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.09846661
43RNA polymerase_Homo sapiens_hsa030201.09761430
44Lysine degradation_Homo sapiens_hsa003101.09512546
45Insulin signaling pathway_Homo sapiens_hsa049101.09372924
46Neurotrophin signaling pathway_Homo sapiens_hsa047221.06143141
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05367638
48Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.04078255
49Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02044897
50Non-homologous end-joining_Homo sapiens_hsa034501.02014613
51Pentose phosphate pathway_Homo sapiens_hsa000301.00188545
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99294323
53Thyroid cancer_Homo sapiens_hsa052160.98124888
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96306182
55Carbon metabolism_Homo sapiens_hsa012000.95676807
56Proteasome_Homo sapiens_hsa030500.95451646
57HTLV-I infection_Homo sapiens_hsa051660.95416418
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.94907743
59T cell receptor signaling pathway_Homo sapiens_hsa046600.94502584
60Legionellosis_Homo sapiens_hsa051340.92403178
61Adherens junction_Homo sapiens_hsa045200.91025384
62Epstein-Barr virus infection_Homo sapiens_hsa051690.89710821
63Fatty acid biosynthesis_Homo sapiens_hsa000610.87227076
64Herpes simplex infection_Homo sapiens_hsa051680.87170266
65Fanconi anemia pathway_Homo sapiens_hsa034600.85902639
66Folate biosynthesis_Homo sapiens_hsa007900.84928945
67Bladder cancer_Homo sapiens_hsa052190.84479332
68Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.83840020
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.83190189
70mTOR signaling pathway_Homo sapiens_hsa041500.82973213
71Hepatitis C_Homo sapiens_hsa051600.82148724
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.79070608
73Proteoglycans in cancer_Homo sapiens_hsa052050.78456748
74Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.78343910
75TGF-beta signaling pathway_Homo sapiens_hsa043500.77950617
76Systemic lupus erythematosus_Homo sapiens_hsa053220.77037955
77Hippo signaling pathway_Homo sapiens_hsa043900.76884776
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.76328085
79Arginine biosynthesis_Homo sapiens_hsa002200.75505978
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.75419296
81Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.74492762
82Choline metabolism in cancer_Homo sapiens_hsa052310.72894626
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69736901
84Viral myocarditis_Homo sapiens_hsa054160.68731589
85Basal transcription factors_Homo sapiens_hsa030220.68552292
86Colorectal cancer_Homo sapiens_hsa052100.66576215
87Melanoma_Homo sapiens_hsa052180.66504919
88Long-term potentiation_Homo sapiens_hsa047200.66178284
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65889793
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.64630062
91Caffeine metabolism_Homo sapiens_hsa002320.63926700
92Acute myeloid leukemia_Homo sapiens_hsa052210.63707755
93Sulfur relay system_Homo sapiens_hsa041220.62983286
94Hepatitis B_Homo sapiens_hsa051610.62667086
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61765904
96Prostate cancer_Homo sapiens_hsa052150.61573444
97Apoptosis_Homo sapiens_hsa042100.60990494
98Oocyte meiosis_Homo sapiens_hsa041140.59569499
99Vitamin B6 metabolism_Homo sapiens_hsa007500.58462048
100Glucagon signaling pathway_Homo sapiens_hsa049220.58017613
101N-Glycan biosynthesis_Homo sapiens_hsa005100.54935105
102Pancreatic cancer_Homo sapiens_hsa052120.54470956
103Focal adhesion_Homo sapiens_hsa045100.54297443
104Prion diseases_Homo sapiens_hsa050200.53910460
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.53688360
106Fructose and mannose metabolism_Homo sapiens_hsa000510.52688390
107Estrogen signaling pathway_Homo sapiens_hsa049150.52305536
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.51583136
109Wnt signaling pathway_Homo sapiens_hsa043100.51098292
110Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.50792167
111Jak-STAT signaling pathway_Homo sapiens_hsa046300.50715008
112Shigellosis_Homo sapiens_hsa051310.49661200
113Non-small cell lung cancer_Homo sapiens_hsa052230.49467592
114Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.48949945
115Basal cell carcinoma_Homo sapiens_hsa052170.48878825
116Glutathione metabolism_Homo sapiens_hsa004800.48029984
117Notch signaling pathway_Homo sapiens_hsa043300.47999495
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.47000600
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.46189002
120ECM-receptor interaction_Homo sapiens_hsa045120.45948080
121HIF-1 signaling pathway_Homo sapiens_hsa040660.45472043
122Endometrial cancer_Homo sapiens_hsa052130.44850459
123Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44591084
124AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.44428357
125PI3K-Akt signaling pathway_Homo sapiens_hsa041510.44322151
126Insulin resistance_Homo sapiens_hsa049310.43697253
127Platelet activation_Homo sapiens_hsa046110.43265108
128Toxoplasmosis_Homo sapiens_hsa051450.41859168
129AMPK signaling pathway_Homo sapiens_hsa041520.41772490
130Measles_Homo sapiens_hsa051620.40611638
131NF-kappa B signaling pathway_Homo sapiens_hsa040640.40432799
132Amoebiasis_Homo sapiens_hsa051460.38115360
133Fat digestion and absorption_Homo sapiens_hsa049750.37881954
134Pathways in cancer_Homo sapiens_hsa052000.37860779
135Tight junction_Homo sapiens_hsa045300.37353052
136Renal cell carcinoma_Homo sapiens_hsa052110.35876323
137Influenza A_Homo sapiens_hsa051640.34969411

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