GSG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1spermatid development (GO:0007286)9.93998060
2plasma membrane fusion (GO:0045026)9.82855396
3epithelial cilium movement (GO:0003351)9.72289442
4axonemal dynein complex assembly (GO:0070286)9.65438702
5motile cilium assembly (GO:0044458)9.41752099
6regulation of cilium movement (GO:0003352)9.35990949
7reproduction (GO:0000003)9.26124041
8cilium or flagellum-dependent cell motility (GO:0001539)8.53510155
9cilium movement (GO:0003341)7.83123678
10negative regulation of inclusion body assembly (GO:0090084)7.65428870
11sperm capacitation (GO:0048240)7.42707238
12single fertilization (GO:0007338)7.39200145
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.30262024
14spermatogenesis (GO:0007283)6.95814951
15synaptonemal complex organization (GO:0070193)6.95803774
16male gamete generation (GO:0048232)6.93286633
17organic cation transport (GO:0015695)6.85773775
18synaptonemal complex assembly (GO:0007130)6.76050374
19male meiosis (GO:0007140)6.75626733
20piRNA metabolic process (GO:0034587)6.72489790
21microtubule depolymerization (GO:0007019)6.68014112
22gamete generation (GO:0007276)6.36824675
23regulation of inclusion body assembly (GO:0090083)6.30784417
24fertilization (GO:0009566)6.29967118
25calcium ion-dependent exocytosis (GO:0017156)5.75779752
26chromosome condensation (GO:0030261)5.62404335
27regulation of microtubule-based movement (GO:0060632)5.53943185
28germ cell development (GO:0007281)5.49472392
29cellular process involved in reproduction in multicellular organism (GO:0022412)5.38931517
30glycerol ether metabolic process (GO:0006662)5.37450716
31DNA packaging (GO:0006323)5.31457962
32ventricular system development (GO:0021591)5.13186972
33multicellular organismal reproductive process (GO:0048609)5.02061266
34cell recognition (GO:0008037)5.01127818
35ether metabolic process (GO:0018904)4.96564957
36spermatid nucleus differentiation (GO:0007289)4.95395445
37microtubule severing (GO:0051013)4.92849975
38behavioral response to nicotine (GO:0035095)4.85791479
39response to pheromone (GO:0019236)4.83862739
40male meiosis I (GO:0007141)4.77225210
41seminiferous tubule development (GO:0072520)4.62752544
42chromosome organization involved in meiosis (GO:0070192)4.54242438
43left/right pattern formation (GO:0060972)4.43189197
44sexual reproduction (GO:0019953)4.40862649
45cellular ketone body metabolic process (GO:0046950)4.32964044
46DNA methylation involved in gamete generation (GO:0043046)4.28329607
47detection of light stimulus involved in sensory perception (GO:0050962)4.21464431
48detection of light stimulus involved in visual perception (GO:0050908)4.21464431
49single strand break repair (GO:0000012)4.19075714
50chaperone-mediated protein complex assembly (GO:0051131)4.16755759
51indolalkylamine metabolic process (GO:0006586)4.09922396
52tryptophan catabolic process (GO:0006569)4.09829714
53indole-containing compound catabolic process (GO:0042436)4.09829714
54indolalkylamine catabolic process (GO:0046218)4.09829714
55multicellular organismal development (GO:0007275)4.05985894
56meiotic nuclear division (GO:0007126)4.05281750
57kynurenine metabolic process (GO:0070189)3.98173482
58establishment of protein localization to Golgi (GO:0072600)3.93210207
59ketone body metabolic process (GO:1902224)3.90358150
60photoreceptor cell maintenance (GO:0045494)3.83659879
61meiosis I (GO:0007127)3.80040387
62protein polyglutamylation (GO:0018095)3.72475238
63genitalia morphogenesis (GO:0035112)3.53785120
64tryptophan metabolic process (GO:0006568)3.50446055
65regulation of spindle checkpoint (GO:0090231)3.48600491
66fucose catabolic process (GO:0019317)3.47328945
67L-fucose metabolic process (GO:0042354)3.47328945
68L-fucose catabolic process (GO:0042355)3.47328945
69protein refolding (GO:0042026)3.45651246
70glycolytic process (GO:0006096)3.41879266
71microtubule polymerization or depolymerization (GO:0031109)3.36741358
72protein targeting to Golgi (GO:0000042)3.34382261
73regulation of action potential (GO:0098900)3.34357165
74detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.28284293
75sequestering of actin monomers (GO:0042989)3.27985848
76mitotic sister chromatid cohesion (GO:0007064)3.19674369
77meiotic cell cycle (GO:0051321)3.19486750
78nonmotile primary cilium assembly (GO:0035058)3.19440232
79nucleus organization (GO:0006997)3.18460318
80RNA localization (GO:0006403)3.17636117
81neuronal action potential (GO:0019228)3.17632357
82indole-containing compound metabolic process (GO:0042430)3.15152579
83amino-acid betaine transport (GO:0015838)3.15085500
84carnitine transport (GO:0015879)3.15085500
85protein K11-linked deubiquitination (GO:0035871)3.12892263
86RNA destabilization (GO:0050779)3.12033817
87water-soluble vitamin biosynthetic process (GO:0042364)3.10468558
88retrograde transport, vesicle recycling within Golgi (GO:0000301)3.03405816
89protein localization to cilium (GO:0061512)3.02346715
90platelet dense granule organization (GO:0060155)2.98769486
91polyamine biosynthetic process (GO:0006596)2.96727943
92interferon-gamma secretion (GO:0072643)2.96598786
93carnitine transmembrane transport (GO:1902603)2.95604141
94phosphatidylethanolamine metabolic process (GO:0046337)2.95394145
95reflex (GO:0060004)2.93997422
96protein localization to Golgi apparatus (GO:0034067)2.93597904
97nucleoside diphosphate phosphorylation (GO:0006165)2.93271811
98phosphatidylethanolamine biosynthetic process (GO:0006646)2.92411702
99polyol catabolic process (GO:0046174)2.92387382
100monoubiquitinated protein deubiquitination (GO:0035520)2.91800410
101preassembly of GPI anchor in ER membrane (GO:0016254)2.91601633
102negative regulation of cytosolic calcium ion concentration (GO:0051481)2.90857022
103retinal cone cell development (GO:0046549)2.90239431
104DNA deamination (GO:0045006)2.89926353
105cellular biogenic amine catabolic process (GO:0042402)2.89417880
106amine catabolic process (GO:0009310)2.89417880
107primary amino compound metabolic process (GO:1901160)2.84876200
108positive regulation of macrophage activation (GO:0043032)2.84015444
109mitochondrion degradation (GO:0000422)2.83818356
110behavioral response to ethanol (GO:0048149)2.81727063
111alditol metabolic process (GO:0019400)2.81324161
112synaptic transmission, cholinergic (GO:0007271)2.81120103
113regulation of cilium assembly (GO:1902017)2.77953691
114cilium organization (GO:0044782)2.77005370
115negative regulation of mast cell activation (GO:0033004)2.74241118
116chromatin silencing (GO:0006342)2.73346631
117regulation of meiosis I (GO:0060631)2.72792474
118centriole replication (GO:0007099)2.72419647
119meiotic cell cycle process (GO:1903046)2.71623015
120transmission of nerve impulse (GO:0019226)2.71616813
121microtubule-based movement (GO:0007018)2.70210776
122signal peptide processing (GO:0006465)2.69990256
123neural tube formation (GO:0001841)2.68462557
124spinal cord motor neuron differentiation (GO:0021522)2.68380967
125regulation of sarcomere organization (GO:0060297)2.67721031
126gamma-aminobutyric acid transport (GO:0015812)2.66332969
127cilium assembly (GO:0042384)2.66326757
128membrane depolarization during action potential (GO:0086010)2.65838244
129positive regulation of glycolytic process (GO:0045821)2.64663726
130synapsis (GO:0007129)2.63773444
131GTP biosynthetic process (GO:0006183)2.62965676
132oxidative demethylation (GO:0070989)2.62220376
133photoreceptor cell development (GO:0042461)2.62132487
134cellular component assembly involved in morphogenesis (GO:0010927)2.60905596
135cilium morphogenesis (GO:0060271)2.60792782
136rhodopsin mediated signaling pathway (GO:0016056)2.60017665
137regulation of hippo signaling (GO:0035330)2.59920575
138G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.59651456
139regulation of rhodopsin mediated signaling pathway (GO:0022400)2.58432639
140axoneme assembly (GO:0035082)2.57450633
141regulation of memory T cell differentiation (GO:0043380)2.56968463
142peptidyl-glutamic acid modification (GO:0018200)2.56518049
143sulfation (GO:0051923)2.55586024
144positive regulation of action potential (GO:0045760)2.53861345
145cAMP catabolic process (GO:0006198)2.53497056
146negative regulation of telomere maintenance (GO:0032205)2.51722238
147negative regulation of organelle assembly (GO:1902116)2.51664516
148sensory perception of light stimulus (GO:0050953)2.50403198
149intraciliary transport (GO:0042073)2.50109931
150visual perception (GO:0007601)2.49781470
151negative regulation of synaptic transmission, GABAergic (GO:0032229)2.48457815
152lactate metabolic process (GO:0006089)2.46130191
153membrane protein intracellular domain proteolysis (GO:0031293)2.42878273
154sperm motility (GO:0030317)14.6557483
155fusion of sperm to egg plasma membrane (GO:0007342)12.8917344
156acrosome reaction (GO:0007340)12.7573859
157cell wall macromolecule catabolic process (GO:0016998)12.1661347
158cell wall macromolecule metabolic process (GO:0044036)12.1661347
159sperm-egg recognition (GO:0035036)11.5341800
160acrosome assembly (GO:0001675)11.1393310
161multicellular organism reproduction (GO:0032504)10.6477015
162binding of sperm to zona pellucida (GO:0007339)10.5041333
163cell-cell recognition (GO:0009988)10.3140618

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.89266989
2EZH2_22144423_ChIP-Seq_EOC_Human4.28039440
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.79277561
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.35807419
5GBX2_23144817_ChIP-Seq_PC3_Human3.10878709
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.88620757
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.68752833
8VDR_22108803_ChIP-Seq_LS180_Human2.67827645
9IGF1R_20145208_ChIP-Seq_DFB_Human2.62475505
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.53415610
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.49550904
12POU3F2_20337985_ChIP-ChIP_501MEL_Human2.41407317
13FUS_26573619_Chip-Seq_HEK293_Human2.39665005
14GATA1_26923725_Chip-Seq_HPCs_Mouse2.34811716
15* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.21791824
16CTBP1_25329375_ChIP-Seq_LNCAP_Human2.18839564
17P300_19829295_ChIP-Seq_ESCs_Human2.11756287
18GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.07066275
19SALL1_21062744_ChIP-ChIP_HESCs_Human2.01751033
20ER_23166858_ChIP-Seq_MCF-7_Human2.01597052
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.99301462
22ZNF274_21170338_ChIP-Seq_K562_Hela1.98983942
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.97892906
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.90324498
25AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.86126968
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.84368737
27FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.82700818
28UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.81970938
29ELK4_26923725_Chip-Seq_MESODERM_Mouse1.81575734
30EWS_26573619_Chip-Seq_HEK293_Human1.79572823
31SMAD4_21799915_ChIP-Seq_A2780_Human1.76175694
32KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.75565583
33STAT3_23295773_ChIP-Seq_U87_Human1.73211083
34STAT1_17558387_ChIP-Seq_HELA_Human1.72431768
35MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.72005169
36SOX2_22085726_ChIP-Seq_NPCs_Mouse1.67996927
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.65949930
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.65227046
39TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65169133
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.61721933
41AR_25329375_ChIP-Seq_VCAP_Human1.60732012
42GATA3_21867929_ChIP-Seq_CD8_Mouse1.55877582
43BCAT_22108803_ChIP-Seq_LS180_Human1.53854429
44WDR5_24793694_ChIP-Seq_LNCAP_Human1.53659634
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.53463461
46FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.53168622
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.51947660
48GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.51527072
49TCF4_23295773_ChIP-Seq_U87_Human1.50951061
50* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.49324276
51PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.47796076
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44656259
53CBP_20019798_ChIP-Seq_JUKART_Human1.44656259
54NR3C1_21868756_ChIP-Seq_MCF10A_Human1.44401609
55REST_21632747_ChIP-Seq_MESCs_Mouse1.44053893
56MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.43302584
57KDM2B_26808549_Chip-Seq_REH_Human1.41349900
58ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.40226917
59SMAD4_21741376_ChIP-Seq_EPCs_Human1.37609273
60KLF5_20875108_ChIP-Seq_MESCs_Mouse1.37415914
61PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37092601
62P53_21459846_ChIP-Seq_SAOS-2_Human1.36830494
63LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.36662761
64TAL1_26923725_Chip-Seq_HPCs_Mouse1.36167085
65RUNX2_22187159_ChIP-Seq_PCA_Human1.35591891
66EZH2_27294783_Chip-Seq_NPCs_Mouse1.35274220
67* SOX2_19829295_ChIP-Seq_ESCs_Human1.34236673
68* NANOG_19829295_ChIP-Seq_ESCs_Human1.34236673
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32837922
70* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.31578102
71RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.31209064
72TCF4_22108803_ChIP-Seq_LS180_Human1.30171277
73TP53_22573176_ChIP-Seq_HFKS_Human1.30131775
74RAD21_21589869_ChIP-Seq_MESCs_Mouse1.29621884
75GATA3_21867929_ChIP-Seq_TH1_Mouse1.28316366
76FOXA1_27270436_Chip-Seq_PROSTATE_Human1.27879250
77FOXA1_25329375_ChIP-Seq_VCAP_Human1.27879250
78BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26742094
79PRDM14_20953172_ChIP-Seq_ESCs_Human1.25042019
80FOXA1_21572438_ChIP-Seq_LNCaP_Human1.24739528
81GF1_26923725_Chip-Seq_HPCs_Mouse1.23906665
82CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23654042
83PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23160408
84MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.22627627
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22009470
86SPI1_26923725_Chip-Seq_HPCs_Mouse1.21584563
87KAP1_22055183_ChIP-Seq_ESCs_Mouse1.20670981
88IRF1_19129219_ChIP-ChIP_H3396_Human1.19828827
89RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19794123
90CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.19376497
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.19298277
92ETV2_25802403_ChIP-Seq_MESCs_Mouse1.19218592
93CBX2_27304074_Chip-Seq_ESCs_Mouse1.18835004
94CTBP2_25329375_ChIP-Seq_LNCAP_Human1.17200204
95TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16846084
96POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16846084
97AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16713431
98TET1_21451524_ChIP-Seq_MESCs_Mouse1.16324953
99SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16075702
100* NCOR_22424771_ChIP-Seq_293T_Human1.15211637
101* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14736059
102SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14655662
103EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14332745
104TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13974510
105TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13731739
106NFE2_27457419_Chip-Seq_LIVER_Mouse1.13639347
107HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.13482952
108RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.13133291
109HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.12999185
110PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.12968342
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12057413
112TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11290863
113GATA3_21878914_ChIP-Seq_MCF-7_Human1.11160108
114YY1_22570637_ChIP-Seq_MALME-3M_Human1.10827076
115* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.10489756
116* CDX2_22108803_ChIP-Seq_LS180_Human1.10349664
117P53_22387025_ChIP-Seq_ESCs_Mouse1.09939925
118JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.09654924
119RUNX1_26923725_Chip-Seq_HPCs_Mouse1.08652964
120* MYC_27129775_Chip-Seq_CORNEA_Mouse1.08452293
121TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07269983
122CTCF_20526341_ChIP-Seq_ESCs_Human1.07197669
123GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06925488
124ERG_20517297_ChIP-Seq_VCAP_Human1.06574433
125RARA_24833708_ChIP-Seq_LIVER_Mouse1.06390120
126GATA1_19941827_ChIP-Seq_MEL86_Mouse1.06161537
127EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.05826730
128E2F1_18555785_Chip-Seq_ESCs_Mouse1.04349559
129ARNT_22903824_ChIP-Seq_MCF-7_Human1.03789151
130SOX11_22085726_ChIP-Seq_ESNs_Mouse1.02326865
131TAF15_26573619_Chip-Seq_HEK293_Human1.02237747
132SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01770876
133ETV1_20927104_ChIP-Seq_GIST48_Human1.01556129
134SOX2_21211035_ChIP-Seq_LN229_Gbm1.01030285
135ESET_19884257_ChIP-Seq_ESCs_Mouse1.01007305
136SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00698818
137STAT3_18555785_Chip-Seq_ESCs_Mouse1.00639520
138NFIB_24661679_ChIP-Seq_LUNG_Mouse1.00407058
139ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.99094451
140OCT4_21477851_ChIP-Seq_ESCs_Mouse0.99017820
141* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99011914
142MYC_19829295_ChIP-Seq_ESCs_Human0.98700578
143SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98420059
144SMAD3_21741376_ChIP-Seq_ESCs_Human0.97830383
145PCGF2_27294783_Chip-Seq_NPCs_Mouse0.97825006
146SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.97637851
147HOXB7_26014856_ChIP-Seq_BT474_Human0.97633007
148ELF1_20517297_ChIP-Seq_JURKAT_Human0.97158833
149CRX_20693478_ChIP-Seq_RETINA_Mouse0.96428424
150NANOG_18555785_Chip-Seq_ESCs_Mouse0.96223776
151BCOR_27268052_Chip-Seq_Bcells_Human0.95530644
152NANOG_20526341_ChIP-Seq_ESCs_Human0.95073365
153* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94768390
154NFYB_21822215_ChIP-Seq_K562_Human0.94601577
155FLI1_21867929_ChIP-Seq_CD8_Mouse0.93215829
156CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.93098160
157RNF2_27304074_Chip-Seq_NSC_Mouse0.91198768
158LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.90417776
159TBL1_22424771_ChIP-Seq_293T_Human0.90066524
160STAT3_18555785_ChIP-Seq_MESCs_Mouse0.89649544
161CTCF_27219007_Chip-Seq_Bcells_Human0.89474411
162PHF8_20622854_ChIP-Seq_HELA_Human0.88159594
163RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87902306
164OCT4_18555785_Chip-Seq_ESCs_Mouse0.86906363
165SOX2_21211035_ChIP-Seq_LN229_Human0.86814144

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.01957255
2MP0001929_abnormal_gametogenesis5.41036660
3MP0008877_abnormal_DNA_methylation3.73141514
4MP0005670_abnormal_white_adipose3.51594484
5MP0002161_abnormal_fertility/fecundity3.30729261
6MP0002210_abnormal_sex_determination3.19824828
7MP0003195_calcinosis2.80176984
8MP0001145_abnormal_male_reproductive2.72478040
9MP0002653_abnormal_ependyma_morphology2.55805096
10MP0000653_abnormal_sex_gland2.34144018
11MP0002837_dystrophic_cardiac_calcinosis2.33764828
12MP0006276_abnormal_autonomic_nervous2.06191776
13MP0005410_abnormal_fertilization16.5737275
14MP0005646_abnormal_pituitary_gland1.84885477
15MP0001485_abnormal_pinna_reflex1.82297647
16MP0001486_abnormal_startle_reflex1.80205017
17MP0003787_abnormal_imprinting1.77853342
18MP0009745_abnormal_behavioral_response1.73177496
19MP0005645_abnormal_hypothalamus_physiol1.70205125
20MP0003880_abnormal_central_pattern1.67878242
21MP0002272_abnormal_nervous_system1.65046310
22MP0006292_abnormal_olfactory_placode1.64055097
23MP0000427_abnormal_hair_cycle1.63845101
24MP0002138_abnormal_hepatobiliary_system1.62592269
25MP0001501_abnormal_sleep_pattern1.60193739
26MP0010386_abnormal_urinary_bladder1.57962535
27MP0001986_abnormal_taste_sensitivity1.56331281
28MP0004233_abnormal_muscle_weight1.56066587
29MP0008872_abnormal_physiological_respon1.53839574
30MP0004142_abnormal_muscle_tone1.49201553
31MP0002735_abnormal_chemical_nociception1.45051944
32MP0003646_muscle_fatigue1.42562677
33MP0000372_irregular_coat_pigmentation1.42218862
34MP0005379_endocrine/exocrine_gland_phen1.39293005
35MP0005623_abnormal_meninges_morphology1.39110642
36MP0001529_abnormal_vocalization1.34976116
37MP0001970_abnormal_pain_threshold1.28567610
38MP0002160_abnormal_reproductive_system1.28294813
39MP0005084_abnormal_gallbladder_morpholo1.27577846
40MP0002557_abnormal_social/conspecific_i1.26500985
41MP0002734_abnormal_mechanical_nocicepti1.25136025
42MP0002733_abnormal_thermal_nociception1.22979038
43MP0002282_abnormal_trachea_morphology1.22955230
44MP0002938_white_spotting1.22875374
45MP0000631_abnormal_neuroendocrine_gland1.22295693
46MP0003252_abnormal_bile_duct1.21089090
47MP0003718_maternal_effect1.18977841
48MP0005174_abnormal_tail_pigmentation1.18519299
49MP0002876_abnormal_thyroid_physiology1.16411489
50MP0000230_abnormal_systemic_arterial1.15623155
51MP0001984_abnormal_olfaction1.14752892
52MP0001765_abnormal_ion_homeostasis1.12755139
53MP0002163_abnormal_gland_morphology1.12529554
54MP0002067_abnormal_sensory_capabilities1.09998418
55MP0002064_seizures1.09956768
56MP0005386_behavior/neurological_phenoty1.09886206
57MP0004924_abnormal_behavior1.09886206
58MP0003635_abnormal_synaptic_transmissio1.09239029
59MP0004885_abnormal_endolymph1.06671495
60MP0002638_abnormal_pupillary_reflex1.06162739
61MP0008875_abnormal_xenobiotic_pharmacok1.03625571
62MP0002822_catalepsy1.03439859
63MP0001963_abnormal_hearing_physiology1.00553990
64MP0002063_abnormal_learning/memory/cond0.97607511
65MP0004147_increased_porphyrin_level0.96870843
66MP0002234_abnormal_pharynx_morphology0.93055433
67MP0003137_abnormal_impulse_conducting0.91666334
68MP0002095_abnormal_skin_pigmentation0.91167336
69MP0008995_early_reproductive_senescence0.89212253
70MP0008789_abnormal_olfactory_epithelium0.88477714
71MP0004215_abnormal_myocardial_fiber0.88268208
72MP0000026_abnormal_inner_ear0.87816024
73MP0002184_abnormal_innervation0.87746454
74MP0003115_abnormal_respiratory_system0.86951789
75MP0001905_abnormal_dopamine_level0.84531478
76MP0008775_abnormal_heart_ventricle0.83296663
77MP0004085_abnormal_heartbeat0.82418969
78MP0000383_abnormal_hair_follicle0.80071052
79MP0003136_yellow_coat_color0.79557392
80MP0005647_abnormal_sex_gland0.78756452
81MP0009046_muscle_twitch0.78255703
82MP0003119_abnormal_digestive_system0.78110871
83MP0003011_delayed_dark_adaptation0.73872768
84MP0008058_abnormal_DNA_repair0.72838007
85MP0001324_abnormal_eye_pigmentation0.72148120
86MP0005666_abnormal_adipose_tissue0.70089302
87MP0005551_abnormal_eye_electrophysiolog0.69317641
88MP0003878_abnormal_ear_physiology0.64408626
89MP0005377_hearing/vestibular/ear_phenot0.64408626
90MP0005389_reproductive_system_phenotype0.61439459
91MP0005636_abnormal_mineral_homeostasis0.60635743
92MP0005253_abnormal_eye_physiology0.60524589
93MP0003329_amyloid_beta_deposits0.56948045
94MP0001764_abnormal_homeostasis0.56443004
95MP0002736_abnormal_nociception_after0.55709032
96MP0003950_abnormal_plasma_membrane0.53842356
97MP0009278_abnormal_bone_marrow0.53510659
98MP0002269_muscular_atrophy0.52683887
99MP0000358_abnormal_cell_content/0.48778274
100MP0001293_anophthalmia0.47925266
101MP0000534_abnormal_ureter_morphology0.47443254
102MP0000569_abnormal_digit_pigmentation0.46555080
103MP0004036_abnormal_muscle_relaxation0.46254028
104MP0003699_abnormal_female_reproductive0.45990422
105MP0001545_abnormal_hematopoietic_system0.44489094
106MP0005397_hematopoietic_system_phenotyp0.44489094
107MP0009115_abnormal_fat_cell0.43071243
108MP0005391_vision/eye_phenotype0.39981139
109MP0002928_abnormal_bile_duct0.35884896
110MP0003942_abnormal_urinary_system0.35288558
111MP0006036_abnormal_mitochondrial_physio0.32695117
112MP0002971_abnormal_brown_adipose0.32261624
113MP0004133_heterotaxia0.32108043
114MP0004811_abnormal_neuron_physiology0.31425901
115MP0001968_abnormal_touch/_nociception0.31266336
116MP0006072_abnormal_retinal_apoptosis0.30752994
117MP0010094_abnormal_chromosome_stability0.30594315
118MP0003633_abnormal_nervous_system0.29698266
119MP0003879_abnormal_hair_cell0.29242602
120MP0008961_abnormal_basal_metabolism0.29060537
121MP0005375_adipose_tissue_phenotype0.28862213
122MP0002152_abnormal_brain_morphology0.27466223
123MP0005195_abnormal_posterior_eye0.27442744
124MP0003948_abnormal_gas_homeostasis0.26804407
125MP0000604_amyloidosis0.26561648
126MP0003861_abnormal_nervous_system0.25888084
127MP0001849_ear_inflammation0.25829933
128MP0003959_abnormal_lean_body0.24909148
129MP0004742_abnormal_vestibular_system0.23725739
130MP0002169_no_abnormal_phenotype0.23677397
131MP0002873_normal_phenotype0.23406718
132MP0000751_myopathy0.23193258
133MP0004019_abnormal_vitamin_homeostasis0.22781002
134MP0001730_embryonic_growth_arrest0.22511866
135MP0003111_abnormal_nucleus_morphology0.22401508
136MP0001727_abnormal_embryo_implantation0.22031658
137MP0003631_nervous_system_phenotype0.21907640
138MP0002295_abnormal_pulmonary_circulatio0.21131878
139MP0001661_extended_life_span0.20377160
140MP0001502_abnormal_circadian_rhythm0.20275656
141MP0009672_abnormal_birth_weight0.19978532
142MP0003786_premature_aging0.19392927
143MP0002229_neurodegeneration0.19384252
144MP0000462_abnormal_digestive_system0.19298179
145MP0001119_abnormal_female_reproductive0.19048785
146MP0003045_fibrosis0.18874146
147MP0004145_abnormal_muscle_electrophysio0.18084096
148MP0004270_analgesia0.17272721
149MP0008569_lethality_at_weaning0.16809041
150MP0002102_abnormal_ear_morphology0.15919032
151MP0005423_abnormal_somatic_nervous0.15467526
152MP0004043_abnormal_pH_regulation0.15232977
153MP0000001_mammalian_phenotype0.14910327
154MP0002108_abnormal_muscle_morphology0.14686720
155MP0002572_abnormal_emotion/affect_behav0.14596805
156MP0003183_abnormal_peptide_metabolism0.14567053
157MP0002909_abnormal_adrenal_gland0.14404896
158MP0002092_abnormal_eye_morphology0.14239338
159MP0002752_abnormal_somatic_nervous0.13877998
160MP0004130_abnormal_muscle_cell0.12588532

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.17971917
2Abnormal respiratory motile cilium morphology (HP:0005938)9.17971917
3Abnormal respiratory motile cilium physiology (HP:0012261)9.07546136
4Infertility (HP:0000789)7.16776611
5Rhinitis (HP:0012384)7.13823758
6Abnormal ciliary motility (HP:0012262)7.07784037
7Chronic bronchitis (HP:0004469)7.06925813
8Nasal polyposis (HP:0100582)6.26861629
9Male infertility (HP:0003251)5.41963129
10Abnormality of the nasal mucosa (HP:0000433)5.16130503
11Bronchitis (HP:0012387)4.52654493
12Pancreatic cysts (HP:0001737)4.39498392
13Bronchiectasis (HP:0002110)4.25965970
14Nephronophthisis (HP:0000090)4.14157311
15Pancreatic fibrosis (HP:0100732)4.11127855
16Chronic hepatic failure (HP:0100626)4.07853414
17True hermaphroditism (HP:0010459)3.87471061
18Abnormal spermatogenesis (HP:0008669)3.85020189
19Congenital stationary night blindness (HP:0007642)3.59666462
20Bony spicule pigmentary retinopathy (HP:0007737)3.53198532
21Abolished electroretinogram (ERG) (HP:0000550)3.42058787
22Progressive cerebellar ataxia (HP:0002073)3.40193349
23Recurrent otitis media (HP:0000403)3.28149196
24Genetic anticipation (HP:0003743)3.20507634
25Recurrent sinusitis (HP:0011108)3.16166902
26Abnormal rod and cone electroretinograms (HP:0008323)3.10385812
27Abnormality of the renal medulla (HP:0100957)3.10160240
28Hyperventilation (HP:0002883)3.06223646
29Type II lissencephaly (HP:0007260)3.05518464
30Impulsivity (HP:0100710)2.92624007
31Abnormality of macular pigmentation (HP:0008002)2.89066958
32Recurrent bronchitis (HP:0002837)2.83140279
33Pendular nystagmus (HP:0012043)2.82837628
34Abnormal gallbladder physiology (HP:0012438)2.80886264
35Cholecystitis (HP:0001082)2.80886264
36Gaze-evoked nystagmus (HP:0000640)2.75367155
37Severe visual impairment (HP:0001141)2.67174518
38Tubulointerstitial nephritis (HP:0001970)2.66448857
39Tubular atrophy (HP:0000092)2.64828066
40Dyschromatopsia (HP:0007641)2.54376615
41Absent rod-and cone-mediated responses on ERG (HP:0007688)2.54258307
42Molar tooth sign on MRI (HP:0002419)2.49515195
43Abnormality of midbrain morphology (HP:0002418)2.49515195
44Renal cortical cysts (HP:0000803)2.44199372
45Congenital sensorineural hearing impairment (HP:0008527)2.43197017
46Febrile seizures (HP:0002373)2.42232829
47Increased corneal curvature (HP:0100692)2.42076268
48Keratoconus (HP:0000563)2.42076268
49Tubulointerstitial abnormality (HP:0001969)2.38835155
50Inability to walk (HP:0002540)2.38183690
51Choroideremia (HP:0001139)2.37807273
52Aplasia/Hypoplasia of the tongue (HP:0010295)2.37533713
53Sclerocornea (HP:0000647)2.36339532
54Intestinal atresia (HP:0011100)2.35467578
55Gonadotropin excess (HP:0000837)2.31566681
56Decreased central vision (HP:0007663)2.31484062
57Nephrogenic diabetes insipidus (HP:0009806)2.31023558
58Medial flaring of the eyebrow (HP:0010747)2.27779157
59Anencephaly (HP:0002323)2.23975973
60Azoospermia (HP:0000027)2.21997772
61Genital tract atresia (HP:0001827)2.19876571
62Aplasia/Hypoplasia of the tibia (HP:0005772)2.18123187
63Optic nerve hypoplasia (HP:0000609)2.16629291
64Lissencephaly (HP:0001339)2.16453754
65Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.15930572
66Spastic tetraparesis (HP:0001285)2.14103938
67Vaginal atresia (HP:0000148)2.10158714
68Polyuria (HP:0000103)2.09331503
69Chorioretinal atrophy (HP:0000533)2.08264198
70Fair hair (HP:0002286)2.04061942
71Tubulointerstitial fibrosis (HP:0005576)2.01173866
72Furrowed tongue (HP:0000221)2.00812984
73Dynein arm defect of respiratory motile cilia (HP:0012255)13.4209204
74Absent/shortened dynein arms (HP:0200106)13.4209204
75Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.6864476
76Focal seizures (HP:0007359)1.99915642
77Type 2 muscle fiber atrophy (HP:0003554)1.98306918
78Retinitis pigmentosa (HP:0000510)1.94190200
79Absent speech (HP:0001344)1.93814143
80Decreased circulating renin level (HP:0003351)1.93770989
81Protruding tongue (HP:0010808)1.92644301
82Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.91267048
83Abnormality of alanine metabolism (HP:0010916)1.91267048
84Hyperalaninemia (HP:0003348)1.91267048
85Heterotopia (HP:0002282)1.90760516
86Large for gestational age (HP:0001520)1.87968209
87Type II diabetes mellitus (HP:0005978)1.86843492
88Hemorrhage of the eye (HP:0011885)1.85024523
89Male pseudohermaphroditism (HP:0000037)1.84547357
90Dialeptic seizures (HP:0011146)1.84483103
91Amelogenesis imperfecta (HP:0000705)1.82893983
92Occipital encephalocele (HP:0002085)1.82540575
93Poor coordination (HP:0002370)1.81300890
94Pachygyria (HP:0001302)1.80621351
95Abnormal drinking behavior (HP:0030082)1.79777332
96Polydipsia (HP:0001959)1.79777332
97Supernumerary spleens (HP:0009799)1.77708028
98Progressive inability to walk (HP:0002505)1.77513714
99Photophobia (HP:0000613)1.76895660
100Neurofibrillary tangles (HP:0002185)1.75430257
101Decreased electroretinogram (ERG) amplitude (HP:0000654)1.72703747
102Postaxial foot polydactyly (HP:0001830)1.72173134
103Broad-based gait (HP:0002136)1.72158632
104Hypoplasia of the fovea (HP:0007750)1.71540531
105Aplasia/Hypoplasia of the fovea (HP:0008060)1.71540531
106Abnormality of the labia minora (HP:0012880)1.70775069
107Stage 5 chronic kidney disease (HP:0003774)1.70758990
108Abnormal biliary tract physiology (HP:0012439)1.70162660
109Bile duct proliferation (HP:0001408)1.70162660
110Methylmalonic acidemia (HP:0002912)1.70007022
111Thyroiditis (HP:0100646)1.69841882
112Scotoma (HP:0000575)1.69061818
113Small hand (HP:0200055)1.68845111
114Central scotoma (HP:0000603)1.67926825
115Gastrointestinal atresia (HP:0002589)1.67074787
116Congenital hepatic fibrosis (HP:0002612)1.66451368
117Bell-shaped thorax (HP:0001591)1.61657989
118Abnormality of renal excretion (HP:0011036)1.60935288
119Congenital malformation of the right heart (HP:0011723)1.59504486
120Double outlet right ventricle (HP:0001719)1.59504486
121Abnormality of the renal cortex (HP:0011035)1.58442004
122Asymmetric septal hypertrophy (HP:0001670)1.56777676
123Hypoplasia of the capital femoral epiphysis (HP:0003090)1.56755090
124Short ribs (HP:0000773)1.56576193
125Exercise-induced myalgia (HP:0003738)1.52580903
126Aplasia/Hypoplasia of the lens (HP:0008063)1.51771696
127Oculomotor apraxia (HP:0000657)1.46647552
128Cerebral inclusion bodies (HP:0100314)1.45849400
129Abnormality of the sella turcica (HP:0002679)1.43923881
130Myoglobinuria (HP:0002913)1.43056737
131Abnormal urine output (HP:0012590)1.42050652
132Hemiparesis (HP:0001269)1.41577296
133Hypercholesterolemia (HP:0003124)1.40915439
134Constricted visual fields (HP:0001133)1.40400458
135Deformed sella turcica (HP:0002681)1.40183748
136Abnormality of the lower motor neuron (HP:0002366)1.38805839
137Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.38718076
138Renal dysplasia (HP:0000110)1.37424303
139Abnormality of dentin (HP:0010299)1.36328925
140Easy fatigability (HP:0003388)1.35488623
141Bundle branch block (HP:0011710)1.35371645
142Postaxial hand polydactyly (HP:0001162)1.35195312
143Loss of speech (HP:0002371)1.34400072
144Cystic liver disease (HP:0006706)1.31713349
145Abnormality of permanent molar morphology (HP:0011071)1.31006085
146Abnormality of the dental root (HP:0006486)1.31006085
147Taurodontia (HP:0000679)1.31006085
148Facial cleft (HP:0002006)1.29737875
149Fibular hypoplasia (HP:0003038)1.29588456
150Truncal obesity (HP:0001956)1.27995954
151Neoplasm of the heart (HP:0100544)1.26946778
152Attenuation of retinal blood vessels (HP:0007843)1.26634614
153Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.24908015
154Absent epiphyses (HP:0010577)1.24908015
155Rhabdomyolysis (HP:0003201)1.23820711
156Abnormality of the dental pulp (HP:0006479)1.22054563
157Fatigable weakness (HP:0003473)1.21471655
158Abnormality of the neuromuscular junction (HP:0003398)1.21471655
159Cerebellar dysplasia (HP:0007033)1.20715631
160Abnormality of molar morphology (HP:0011070)1.20671787
161Abnormality of molar (HP:0011077)1.20671787
162Sensory axonal neuropathy (HP:0003390)1.19690628
163Broad distal phalanx of finger (HP:0009836)1.19636732
164Amyotrophic lateral sclerosis (HP:0007354)1.18599733
165Gait imbalance (HP:0002141)1.16997603
166Congenital primary aphakia (HP:0007707)1.16881034
167Polymicrogyria (HP:0002126)1.16542140
168Short femoral neck (HP:0100864)1.15898883

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.53610120
2PDK47.53610120
3FRK6.97739093
4TESK16.76481497
5PRKD35.98569279
6ICK5.16023498
7PDK24.88845847
8BMPR1B3.22535248
9MAP4K23.18615696
10ADRBK22.81755250
11ACVR1B2.51271402
12INSRR2.40214956
13WNK32.37520865
14PTK2B2.25337567
15ZAK2.22082643
16GRK12.19599879
17WNK42.07867155
18NUAK12.06944990
19STK391.94976228
20STK381.93807805
21DYRK1B1.90940933
22PNCK1.89556942
23MAP3K41.76604200
24OXSR11.75081876
25TAOK31.60548194
26PLK21.55199080
27NEK21.51427541
28TLK11.50239428
29MAPK131.49390012
30MKNK21.39943395
31CASK1.34689759
32CDK191.33086368
33DAPK21.26644614
34AKT31.26493985
35TRIM281.25539900
36PDK11.20647144
37TXK1.17814358
38TGFBR11.17341350
39TYRO31.11891409
40TNIK1.08531893
41MAP2K71.08078909
42MAPK151.05464082
43PAK30.96658401
44PIK3CG0.96500428
45DYRK30.95338778
46ERBB30.95102479
47PRKCE0.94072945
48ADRBK10.89457622
49CAMKK20.88576458
50CDK80.86010697
51WNK10.84319633
52TIE10.82048242
53PDPK10.79728122
54CSNK1G20.79553206
55BCR0.78057964
56CSNK1G10.75807584
57PINK10.75716132
58TEC0.74350942
59CSNK1G30.73568527
60RIPK40.72669261
61NTRK30.69880138
62CSNK1A1L0.69164139
63VRK10.68218487
64EEF2K0.67469738
65IRAK10.67251315
66FGFR20.66239160
67PASK0.64271539
68SIK20.63471488
69MKNK10.62441987
70TESK20.59517156
71DYRK20.59325438
72EIF2AK30.58856683
73CAMK10.58713325
74CAMK1G0.58006270
75TNK20.57737131
76CCNB10.57694766
77STK30.56878192
78TTK0.56754135
79CHEK20.55174287
80MAP2K60.54118577
81NTRK20.52748585
82FER0.52477319
83OBSCN0.52051312
84IRAK20.49893369
85SGK20.49487745
86LMTK20.47227434
87PAK10.45600555
88PIK3CA0.45129601
89PRKACA0.42486089
90PHKG20.41278586
91PHKG10.41278586
92BRD40.41137959
93PRKAA20.41015601
94TAF10.40259496
95LATS10.40184321
96STK160.40013007
97IKBKB0.38757896
98PRKCG0.38674081
99STK38L0.38554699
100PKN10.38062546
101CHEK10.38013846
102SGK2230.37453726
103SGK4940.37453726
104KIT0.36632565
105PAK20.36019377
106PRKCH0.35657773
107CAMK1D0.35626273
108MUSK0.33953667
109MAP3K100.33233723
110CSNK1A10.32491168
111EPHA40.32312933
112MARK20.31924088
113PLK30.30962389
114MTOR0.30918196
115BCKDK0.30687809
116PAK40.29061676
117MINK10.28355494
118NEK60.27256832
119ATM0.25195924
120PRKCZ0.23552723
121CAMKK10.22857588
122MAPKAPK50.22649402
123ATR0.22294746
124PRKAA10.21094337
125CDK150.18532906
126RPS6KB10.17556716
127CDK180.16151657
128PAK60.16024970
129PRKCQ0.14908262
130CDK11A0.14510363
131PRKG20.11630126
132CDK140.10131496
133PLK10.09469805
134GSK3B0.09219604
135RPS6KA10.08863580
136BRSK20.08293655
137CLK10.07979806
138CSNK2A10.07561775
139WEE10.05847261
140PRKCD0.05452069
141BRSK10.05249969
142CDK60.05107308
143PIM10.04981356
144PLK40.04354587
145CAMK2A0.03964148
146CDK10.03365263
147CDK20.03325901
148PRKACG0.03292232
149CDK120.03260945
150BRAF0.02807394
151CSNK1D0.02770737
152STK110.02260758
153PRKG10.02216682
154PRKCA0.02074246
155MAPK80.01847923
156STK100.01750115
157MAP3K10.01673328
158CDC70.01248316
159PRKCB0.00950981
160AURKA0.00881967
161CSNK2A20.00861797
162DDR20.00830153
163MARK1-0.0168410
164PDGFRB-0.0154554
165RPS6KA3-0.0073204
166CSK-0.0063867
167MARK3-0.0053537
168YES1-0.0044337
169CSF1R-0.0035608
170PRKD2-0.0023616
171TAOK1-0.0022300
172EGFR-0.0016345
173TRIB3-0.0004482

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000615.10875014
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.56158147
3alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.16707949
4Phototransduction_Homo sapiens_hsa047443.16596320
5Pyruvate metabolism_Homo sapiens_hsa006203.11197857
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.09654396
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.08498937
8Linoleic acid metabolism_Homo sapiens_hsa005913.03310714
9Vitamin B6 metabolism_Homo sapiens_hsa007502.99493347
10Butanoate metabolism_Homo sapiens_hsa006502.66639894
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.62883380
12Carbohydrate digestion and absorption_Homo sapiens_hsa049732.58803083
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.50930894
14Glucagon signaling pathway_Homo sapiens_hsa049222.43298150
15Propanoate metabolism_Homo sapiens_hsa006402.26569640
16Nitrogen metabolism_Homo sapiens_hsa009102.17940178
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.12708871
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.09599006
19Olfactory transduction_Homo sapiens_hsa047402.05639841
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.03489563
21Basal transcription factors_Homo sapiens_hsa030222.02657533
22Glycerolipid metabolism_Homo sapiens_hsa005611.98456568
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.96397702
24PPAR signaling pathway_Homo sapiens_hsa033201.91613210
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.86953759
26Fructose and mannose metabolism_Homo sapiens_hsa000511.86899539
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.84664732
28Tryptophan metabolism_Homo sapiens_hsa003801.82443614
29Glycerophospholipid metabolism_Homo sapiens_hsa005641.79942436
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.75893007
31Morphine addiction_Homo sapiens_hsa050321.73989536
32Selenocompound metabolism_Homo sapiens_hsa004501.70609163
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.68256633
34Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.67651280
35Mineral absorption_Homo sapiens_hsa049781.63269921
36Primary bile acid biosynthesis_Homo sapiens_hsa001201.61590788
37Fatty acid metabolism_Homo sapiens_hsa012121.57590244
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.56879606
39Fat digestion and absorption_Homo sapiens_hsa049751.52099107
40Homologous recombination_Homo sapiens_hsa034401.49184949
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48849435
42Oocyte meiosis_Homo sapiens_hsa041141.47193490
43Fatty acid degradation_Homo sapiens_hsa000711.46592919
44Dorso-ventral axis formation_Homo sapiens_hsa043201.44775085
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.44029574
46Pentose phosphate pathway_Homo sapiens_hsa000301.43413822
47Protein export_Homo sapiens_hsa030601.42127178
48GABAergic synapse_Homo sapiens_hsa047271.40744685
49Amphetamine addiction_Homo sapiens_hsa050311.38953869
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.38805445
51Ether lipid metabolism_Homo sapiens_hsa005651.36249098
52Steroid hormone biosynthesis_Homo sapiens_hsa001401.36183845
53Retinol metabolism_Homo sapiens_hsa008301.35817883
54Carbon metabolism_Homo sapiens_hsa012001.33191006
55Cardiac muscle contraction_Homo sapiens_hsa042601.32484884
56Caffeine metabolism_Homo sapiens_hsa002321.32433580
57Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.28275186
58Glycosaminoglycan degradation_Homo sapiens_hsa005311.26320545
59Glutamatergic synapse_Homo sapiens_hsa047241.25097816
60Intestinal immune network for IgA production_Homo sapiens_hsa046721.21342646
61Serotonergic synapse_Homo sapiens_hsa047261.18012543
62RNA polymerase_Homo sapiens_hsa030201.17023024
63Oxidative phosphorylation_Homo sapiens_hsa001901.14769638
64Hedgehog signaling pathway_Homo sapiens_hsa043401.12819768
65Peroxisome_Homo sapiens_hsa041461.09658106
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09512223
67Renin secretion_Homo sapiens_hsa049241.06159089
68Fanconi anemia pathway_Homo sapiens_hsa034601.05155534
69Antigen processing and presentation_Homo sapiens_hsa046121.02277638
70Cysteine and methionine metabolism_Homo sapiens_hsa002701.00219121
71Biosynthesis of amino acids_Homo sapiens_hsa012300.99134117
72mRNA surveillance pathway_Homo sapiens_hsa030150.95863363
73Collecting duct acid secretion_Homo sapiens_hsa049660.94915874
74Insulin secretion_Homo sapiens_hsa049110.93727677
75Asthma_Homo sapiens_hsa053100.93365140
76Purine metabolism_Homo sapiens_hsa002300.90286684
77Type I diabetes mellitus_Homo sapiens_hsa049400.88522628
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.86572909
79beta-Alanine metabolism_Homo sapiens_hsa004100.85734664
80RNA degradation_Homo sapiens_hsa030180.85221855
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.84275899
82Arachidonic acid metabolism_Homo sapiens_hsa005900.81633394
83Glutathione metabolism_Homo sapiens_hsa004800.81461254
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81343019
85Bile secretion_Homo sapiens_hsa049760.80195090
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78550774
87One carbon pool by folate_Homo sapiens_hsa006700.77936998
88Thyroid hormone synthesis_Homo sapiens_hsa049180.76904539
89Regulation of autophagy_Homo sapiens_hsa041400.76292404
90Estrogen signaling pathway_Homo sapiens_hsa049150.74719781
91Chemical carcinogenesis_Homo sapiens_hsa052040.74436829
92RNA transport_Homo sapiens_hsa030130.72396617
93cGMP-PKG signaling pathway_Homo sapiens_hsa040220.72134851
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.71754683
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70916576
96Central carbon metabolism in cancer_Homo sapiens_hsa052300.69550601
97Huntingtons disease_Homo sapiens_hsa050160.68904131
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.68665137
99Synaptic vesicle cycle_Homo sapiens_hsa047210.68490012
100Parkinsons disease_Homo sapiens_hsa050120.65332561
101Salivary secretion_Homo sapiens_hsa049700.64240452
102Graft-versus-host disease_Homo sapiens_hsa053320.64120269
103Dopaminergic synapse_Homo sapiens_hsa047280.63825093
104Legionellosis_Homo sapiens_hsa051340.62887496
105Long-term potentiation_Homo sapiens_hsa047200.61668024
106SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60444757
107Ovarian steroidogenesis_Homo sapiens_hsa049130.59056697
108Histidine metabolism_Homo sapiens_hsa003400.54806205
109Pancreatic secretion_Homo sapiens_hsa049720.54375177
110ABC transporters_Homo sapiens_hsa020100.54123230
111Endocytosis_Homo sapiens_hsa041440.53312666
112Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52766458
113Renin-angiotensin system_Homo sapiens_hsa046140.51942605
114Protein digestion and absorption_Homo sapiens_hsa049740.51873695
115Circadian rhythm_Homo sapiens_hsa047100.51710330
116Autoimmune thyroid disease_Homo sapiens_hsa053200.51392925
117Calcium signaling pathway_Homo sapiens_hsa040200.49268507
118Cholinergic synapse_Homo sapiens_hsa047250.48821626
119Allograft rejection_Homo sapiens_hsa053300.48633174
120AMPK signaling pathway_Homo sapiens_hsa041520.47528807
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47270269
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.46058121
123Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45311865
124Non-homologous end-joining_Homo sapiens_hsa034500.44907018
125Gastric acid secretion_Homo sapiens_hsa049710.44560863
126Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44137655
127Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.43458897
128Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42777232
129Long-term depression_Homo sapiens_hsa047300.42286279
130Oxytocin signaling pathway_Homo sapiens_hsa049210.40021921
131Alzheimers disease_Homo sapiens_hsa050100.39844950
132Circadian entrainment_Homo sapiens_hsa047130.39131603
133VEGF signaling pathway_Homo sapiens_hsa043700.37782657
134Systemic lupus erythematosus_Homo sapiens_hsa053220.36309230
135Phosphatidylinositol signaling system_Homo sapiens_hsa040700.35384049
136Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.34791016
137Steroid biosynthesis_Homo sapiens_hsa001000.34539760
138Inositol phosphate metabolism_Homo sapiens_hsa005620.34385937
139Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.33276241
140Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33027560
141Metabolic pathways_Homo sapiens_hsa011000.32715895
142cAMP signaling pathway_Homo sapiens_hsa040240.32121799
143Pentose and glucuronate interconversions_Homo sapiens_hsa000400.32020086
144Taste transduction_Homo sapiens_hsa047420.27718124
145Basal cell carcinoma_Homo sapiens_hsa052170.22805346
146Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.21940139
147Alcoholism_Homo sapiens_hsa050340.19447723
148Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.19287715
149HIF-1 signaling pathway_Homo sapiens_hsa040660.18139069
150Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.17546105
151Cocaine addiction_Homo sapiens_hsa050300.16807054
152Sulfur metabolism_Homo sapiens_hsa009200.16355984
153N-Glycan biosynthesis_Homo sapiens_hsa005100.16226788
154Pyrimidine metabolism_Homo sapiens_hsa002400.12852742
155Wnt signaling pathway_Homo sapiens_hsa043100.11742454
156Nicotine addiction_Homo sapiens_hsa050330.10937815
157Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.09965345
158Type II diabetes mellitus_Homo sapiens_hsa049300.07079970

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