GPR174

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.90808022
2negative T cell selection (GO:0043383)6.88325685
3negative thymic T cell selection (GO:0045060)6.67645704
4positive thymic T cell selection (GO:0045059)6.39842831
5positive T cell selection (GO:0043368)6.25964379
6positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.98084961
7regulation of isotype switching to IgG isotypes (GO:0048302)5.98027284
8cellular response to interleukin-15 (GO:0071350)5.90743775
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.85335495
10negative regulation of cell killing (GO:0031342)5.85335495
11thymic T cell selection (GO:0045061)5.71670406
12response to interleukin-15 (GO:0070672)5.71667790
13interferon-gamma production (GO:0032609)5.60678551
14T cell selection (GO:0045058)5.58226672
15antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.56874797
16positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.33482858
17regulation of gamma-delta T cell differentiation (GO:0045586)5.09424032
18T cell migration (GO:0072678)5.05977244
19regulation of alpha-beta T cell proliferation (GO:0046640)4.92579114
20regulation of B cell receptor signaling pathway (GO:0050855)4.86009771
21regulation of gamma-delta T cell activation (GO:0046643)4.84578316
22activated T cell proliferation (GO:0050798)4.75140598
23positive regulation of granulocyte differentiation (GO:0030854)4.71578188
24leukocyte aggregation (GO:0070486)4.69971135
25regulation of interleukin-2 biosynthetic process (GO:0045076)4.65461851
26antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.62664422
27antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.62664422
28regulation of regulatory T cell differentiation (GO:0045589)4.60963304
29antigen processing and presentation of endogenous antigen (GO:0019883)4.57716764
30regulation of T cell tolerance induction (GO:0002664)4.57072969
31negative regulation of T cell mediated immunity (GO:0002710)4.56024633
32positive regulation of alpha-beta T cell proliferation (GO:0046641)4.55632508
33T cell receptor signaling pathway (GO:0050852)4.54465856
34regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.46636296
35positive regulation of interleukin-2 production (GO:0032743)4.42189740
36T cell costimulation (GO:0031295)4.41927439
37lymphocyte costimulation (GO:0031294)4.37836185
38antigen receptor-mediated signaling pathway (GO:0050851)4.32145616
39tolerance induction (GO:0002507)4.24529932
40positive regulation of B cell differentiation (GO:0045579)4.08728901
41B cell receptor signaling pathway (GO:0050853)4.03632106
42positive regulation of isotype switching (GO:0045830)4.03529302
43regulation of interleukin-12 biosynthetic process (GO:0045075)4.01283832
44regulation of isotype switching (GO:0045191)4.00386114
45regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.95640492
46positive regulation of DNA recombination (GO:0045911)3.82228658
47regulation of T cell receptor signaling pathway (GO:0050856)3.72442002
48natural killer cell differentiation (GO:0001779)3.65670320
49positive regulation of humoral immune response (GO:0002922)3.61355925
50negative regulation of lymphocyte mediated immunity (GO:0002707)3.59822593
51regulation of immunoglobulin mediated immune response (GO:0002889)3.58779503
52positive regulation of B cell mediated immunity (GO:0002714)3.57669611
53positive regulation of immunoglobulin mediated immune response (GO:0002891)3.57669611
54regulation of B cell mediated immunity (GO:0002712)3.54720323
55regulation of interleukin-2 production (GO:0032663)3.54385506
56regulation of B cell differentiation (GO:0045577)3.53744515
57CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.53009883
58regulation of immunoglobulin production (GO:0002637)3.50398477
59positive regulation of tolerance induction (GO:0002645)3.48763413
60alpha-beta T cell differentiation (GO:0046632)3.44138754
61hepatocyte apoptotic process (GO:0097284)3.43646046
62positive regulation by symbiont of host defense response (GO:0052509)3.42620542
63modulation by symbiont of host defense response (GO:0052031)3.42620542
64modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.42620542
65modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.42620542
66positive regulation by organism of defense response of other organism involved in symbiotic interact3.42620542
67modulation by symbiont of host immune response (GO:0052553)3.42620542
68mast cell activation (GO:0045576)3.42125779
69negative regulation of leukocyte mediated immunity (GO:0002704)3.38142580
70positive regulation of immunoglobulin production (GO:0002639)3.38007669
71positive regulation of natural killer cell mediated immunity (GO:0002717)3.37505567
72positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.37505567
73regulation of natural killer cell mediated immunity (GO:0002715)3.37290058
74regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.37290058
75alpha-beta T cell activation (GO:0046631)3.36288103
76negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.32849914
77regulation of tolerance induction (GO:0002643)3.32376959
78B cell proliferation (GO:0042100)3.28281880
79positive regulation of interleukin-4 production (GO:0032753)3.27595101
80T cell homeostasis (GO:0043029)3.27442773
81negative regulation of interleukin-12 production (GO:0032695)3.20699321
82regulation of granulocyte differentiation (GO:0030852)3.20049932
83regulation of alpha-beta T cell activation (GO:0046634)3.19780126
84T cell differentiation (GO:0030217)3.18981460
85regulation of B cell proliferation (GO:0030888)3.17611637
86positive regulation of B cell proliferation (GO:0030890)3.16298554
87T cell proliferation (GO:0042098)3.13786463
88Peyers patch development (GO:0048541)3.11805823
89mucosal-associated lymphoid tissue development (GO:0048537)3.11805823
90cellular extravasation (GO:0045123)3.10635119
91negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.08651192
92regulation of T cell mediated cytotoxicity (GO:0001914)3.06705779
93mature B cell differentiation (GO:0002335)3.06366298
94regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)3.06191323
95natural killer cell activation (GO:0030101)3.06084837
96phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.05747729
97immune response-activating cell surface receptor signaling pathway (GO:0002429)3.04593643
98regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.04208451
99T-helper cell differentiation (GO:0042093)3.03819521
100CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.03819521
101negative regulation of adaptive immune response (GO:0002820)3.01980157
102antigen processing and presentation via MHC class Ib (GO:0002475)3.00934783
103lymphocyte homeostasis (GO:0002260)3.00712675
104myeloid dendritic cell activation (GO:0001773)3.00513143
105B cell homeostasis (GO:0001782)2.99846586
106cellular response to type I interferon (GO:0071357)2.99508765
107type I interferon signaling pathway (GO:0060337)2.99508765
108response to type I interferon (GO:0034340)2.98465837
109positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.97469064
110regulation of interleukin-4 production (GO:0032673)2.97449975
111response to muramyl dipeptide (GO:0032495)2.97370612
112negative regulation of B cell proliferation (GO:0030889)2.95860742
113detection of other organism (GO:0098543)2.95222525
114positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.94953746
115NIK/NF-kappaB signaling (GO:0038061)2.94717830
116positive regulation of B cell activation (GO:0050871)2.92516928
117regulation of chronic inflammatory response (GO:0002676)2.90015038
118regulation of leukocyte mediated cytotoxicity (GO:0001910)2.89995369
119regulation of lymphocyte mediated immunity (GO:0002706)2.88387947
120negative regulation of erythrocyte differentiation (GO:0045647)2.88018131
121positive regulation of T cell activation (GO:0050870)2.87875802
122T cell differentiation involved in immune response (GO:0002292)2.87572727
123alpha-beta T cell differentiation involved in immune response (GO:0002293)2.87572727
124alpha-beta T cell activation involved in immune response (GO:0002287)2.87572727
125regulation of cell killing (GO:0031341)2.86381265
126T cell activation (GO:0042110)2.86265756
127CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.85399320
128positive regulation of T cell proliferation (GO:0042102)2.84990293
129T cell lineage commitment (GO:0002360)2.84848458
130regulation of B cell activation (GO:0050864)2.84601015
131detection of bacterium (GO:0016045)2.84573576
132positive regulation of cell killing (GO:0031343)2.81558562
133positive regulation of T cell mediated cytotoxicity (GO:0001916)2.80851393
134positive regulation of alpha-beta T cell activation (GO:0046635)2.79919012

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.81376380
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.92688814
3RUNX_20019798_ChIP-Seq_JUKART_Human4.08572317
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.97982390
5* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.88773679
6IRF8_22096565_ChIP-ChIP_GC-B_Human3.81655221
7FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.43918778
8STAT4_19710469_ChIP-ChIP_TH1__Mouse3.17650625
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.15557718
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.82258421
11* MYB_26560356_Chip-Seq_TH2_Human2.70255663
12NOTCH1_21737748_ChIP-Seq_TLL_Human2.67308762
13IRF8_21731497_ChIP-ChIP_J774_Mouse2.64577840
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.58758808
15SMAD_19615063_ChIP-ChIP_OVARY_Human2.52789452
16* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.50622439
17VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.48697415
18MYB_26560356_Chip-Seq_TH1_Human2.27033578
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.21025875
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.18968296
21IRF8_27001747_Chip-Seq_BMDM_Mouse2.09202416
22MAF_26560356_Chip-Seq_TH1_Human2.07742412
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.01951671
24GATA1_22025678_ChIP-Seq_K562_Human1.94315490
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.88109337
26SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.86317837
27BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.81406523
28UTX_26944678_Chip-Seq_JUKART_Human1.76373115
29MYC_22102868_ChIP-Seq_BL_Human1.70633274
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68778974
31AR_21572438_ChIP-Seq_LNCaP_Human1.62660843
32GATA3_27048872_Chip-Seq_THYMUS_Human1.59698956
33RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.59387286
34CIITA_25753668_ChIP-Seq_RAJI_Human1.58659518
35PCGF2_27294783_Chip-Seq_NPCs_Mouse1.52569454
36NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.51225600
37SCL_19346495_ChIP-Seq_HPC-7_Human1.50371086
38Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.45129344
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.44979136
40MAF_26560356_Chip-Seq_TH2_Human1.42057715
41KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41246693
42RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.39973348
43IKZF1_21737484_ChIP-ChIP_HCT116_Human1.39675930
44KDM2B_26808549_Chip-Seq_DND41_Human1.39425950
45* TAF15_26573619_Chip-Seq_HEK293_Human1.38336004
46TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.36176751
47GATA2_22383799_ChIP-Seq_G1ME_Mouse1.35877725
48SPI1_23547873_ChIP-Seq_NB4_Human1.35746211
49NFE2_27457419_Chip-Seq_LIVER_Mouse1.34530849
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.34089845
51SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.33767586
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.29744891
53E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.27805477
54RUNX1_22412390_ChIP-Seq_EML_Mouse1.24478924
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.22391834
56EZH2_27294783_Chip-Seq_NPCs_Mouse1.21472589
57GATA3_26560356_Chip-Seq_TH2_Human1.20158709
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.20030398
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.19479285
60MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.18710910
61RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.17777795
62VDR_21846776_ChIP-Seq_THP-1_Human1.15220350
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13663057
64PU_27001747_Chip-Seq_BMDM_Mouse1.13577794
65KDM2B_26808549_Chip-Seq_JURKAT_Human1.11321609
66KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10158463
67GATA1_19941826_ChIP-Seq_K562_Human1.08083101
68VDR_24763502_ChIP-Seq_THP-1_Human1.07289892
69IRF1_19129219_ChIP-ChIP_H3396_Human1.06670303
70GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06341996
71PRDM14_20953172_ChIP-Seq_ESCs_Human1.06075753
72POU3F2_20337985_ChIP-ChIP_501MEL_Human1.06030729
73TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.05899332
74VDR_23849224_ChIP-Seq_CD4+_Human1.04519585
75VDR_24787735_ChIP-Seq_THP-1_Human1.02480366
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.02175022
77MYB_21317192_ChIP-Seq_ERMYB_Mouse1.01942217
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.01801901
79NMYC_18555785_Chip-Seq_ESCs_Mouse1.00460716
80TP63_19390658_ChIP-ChIP_HaCaT_Human1.00076177
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99180155
82SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99070989
83CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.98138333
84GBX2_23144817_ChIP-Seq_PC3_Human0.97507693
85ELF1_17652178_ChIP-ChIP_JURKAT_Human0.97457979
86CMYC_18555785_Chip-Seq_ESCs_Mouse0.96762833
87GATA1_22383799_ChIP-Seq_G1ME_Mouse0.96513459
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96385524
89* LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.95281889
90EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95235043
91NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.93952179
92GATA2_19941826_ChIP-Seq_K562_Human0.93419217
93P53_22387025_ChIP-Seq_ESCs_Mouse0.92585922
94PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92548438
95OCT4_21477851_ChIP-Seq_ESCs_Mouse0.91530869
96CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.91082031
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90293769
98FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89742745
99EZH2_22144423_ChIP-Seq_EOC_Human0.89530074
100SPI1_23127762_ChIP-Seq_K562_Human0.89210516
101P300_18555785_Chip-Seq_ESCs_Mouse0.88423347
102CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.88163670
103RUNX1_27457419_Chip-Seq_LIVER_Mouse0.87756529
104E2F1_18555785_Chip-Seq_ESCs_Mouse0.87724801
105STAT3_18555785_Chip-Seq_ESCs_Mouse0.86778113
106P300_19829295_ChIP-Seq_ESCs_Human0.86142611
107OCT4_18555785_Chip-Seq_ESCs_Mouse0.85520060
108EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.85025665
109* LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.84920520
110SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.84521361
111SMRT_27268052_Chip-Seq_Bcells_Human0.84033464
112ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.83888782
113PU1_27457419_Chip-Seq_LIVER_Mouse0.83589564
114CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.83360418
115CRX_20693478_ChIP-Seq_RETINA_Mouse0.82548433
116FOXP3_21729870_ChIP-Seq_TREG_Human0.82546844
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82092480
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.81953372
119CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.81228267
120GATA3_26560356_Chip-Seq_TH1_Human0.81193620
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81122591
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.81122591
123CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80869686
124RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80806476
125HOXB4_20404135_ChIP-ChIP_EML_Mouse0.79904300
126TCF7_22412390_ChIP-Seq_EML_Mouse0.79213005
127PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78754299
128* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.76287325
129NCOR1_26117541_ChIP-Seq_K562_Human0.75814257
130BRD4_27068464_Chip-Seq_AML-cells_Mouse0.75790731
131ESRRB_18555785_Chip-Seq_ESCs_Mouse0.75671115
132PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.75547678
133ZFX_18555785_Chip-Seq_ESCs_Mouse0.74744871
134CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.74730891
135FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73646194
136SOX2_18555785_Chip-Seq_ESCs_Mouse0.73349644
137VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.73114049
138GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.71276980
139CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.70506922
140PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.70020787
141PU.1_20513432_ChIP-Seq_Bcells_Mouse0.68039319
142GATA2_21666600_ChIP-Seq_HMVEC_Human0.66374208
143* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.65666288

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.89584552
2MP0005671_abnormal_response_to4.54309440
3MP0001835_abnormal_antigen_presentation3.94776038
4MP0001790_abnormal_immune_system3.80497467
5MP0005387_immune_system_phenotype3.80497467
6MP0001800_abnormal_humoral_immune3.74463622
7MP0005000_abnormal_immune_tolerance3.29490804
8MP0000685_abnormal_immune_system3.01712696
9MP0002723_abnormal_immune_serum2.97725869
10MP0002420_abnormal_adaptive_immunity2.91018481
11MP0002452_abnormal_antigen_presenting2.89406625
12MP0001819_abnormal_immune_cell2.84720393
13MP0002398_abnormal_bone_marrow2.59477982
14MP0001873_stomach_inflammation2.56870744
15MP0009785_altered_susceptibility_to2.56093267
16MP0006082_CNS_inflammation2.50572543
17MP0002148_abnormal_hypersensitivity_rea2.46216860
18MP0005025_abnormal_response_to2.40811292
19MP0000716_abnormal_immune_system2.38373942
20MP0004381_abnormal_hair_follicle2.37146751
21MP0009333_abnormal_splenocyte_physiolog2.32235233
22MP0002405_respiratory_system_inflammati2.31618132
23MP0003436_decreased_susceptibility_to2.23690947
24MP0003303_peritoneal_inflammation2.21224661
25MP0003724_increased_susceptibility_to2.19778537
26MP0002166_altered_tumor_susceptibility2.18246756
27MP0000703_abnormal_thymus_morphology2.12138658
28MP0000689_abnormal_spleen_morphology2.06985300
29MP0002722_abnormal_immune_system2.00491092
30MP0002006_tumorigenesis1.98756348
31MP0000569_abnormal_digit_pigmentation1.92482683
32MP0002933_joint_inflammation1.91306281
33MP0002419_abnormal_innate_immunity1.90599995
34MP0003866_abnormal_defecation1.86293321
35MP0002429_abnormal_blood_cell1.83298875
36MP0010155_abnormal_intestine_physiology1.78930596
37MP0004510_myositis1.71027065
38MP0002396_abnormal_hematopoietic_system1.69472980
39MP0005310_abnormal_salivary_gland1.62900382
40MP0001845_abnormal_inflammatory_respons1.50061573
41MP0004947_skin_inflammation1.49520984
42MP0003300_gastrointestinal_ulcer1.49305575
43MP0001853_heart_inflammation1.48987612
44MP0003787_abnormal_imprinting1.47142173
45MP0003172_abnormal_lysosome_physiology1.47034386
46MP0000465_gastrointestinal_hemorrhage1.39287280
47MP0002277_abnormal_respiratory_mucosa1.33639647
48MP0002132_abnormal_respiratory_system1.29861640
49MP0005464_abnormal_platelet_physiology1.25610636
50MP0003828_pulmonary_edema1.24604263
51MP0008057_abnormal_DNA_replication1.15119056
52MP0002009_preneoplasia1.12132245
53MP0004742_abnormal_vestibular_system1.09172133
54MP0001986_abnormal_taste_sensitivity1.08591880
55MP0005075_abnormal_melanosome_morpholog1.05679321
56MP0002138_abnormal_hepatobiliary_system1.05414752
57MP0003221_abnormal_cardiomyocyte_apopto1.05058638
58MP0008877_abnormal_DNA_methylation1.03979256
59MP0003448_altered_tumor_morphology1.03691962
60MP0001851_eye_inflammation1.03150035
61MP0004883_abnormal_blood_vessel1.02077467
62MP0005451_abnormal_body_composition0.99581887
63MP0005174_abnormal_tail_pigmentation0.97244544
64MP0002102_abnormal_ear_morphology0.96007150
65MP0003656_abnormal_erythrocyte_physiolo0.95372414
66MP0005409_darkened_coat_color0.91021429
67MP0009278_abnormal_bone_marrow0.89854876
68MP0000858_altered_metastatic_potential0.89844119
69MP0000490_abnormal_crypts_of0.89355537
70MP0004808_abnormal_hematopoietic_stem0.89245741
71MP0005645_abnormal_hypothalamus_physiol0.88797328
72MP0003136_yellow_coat_color0.88290583
73MP0008469_abnormal_protein_level0.87589694
74MP0001533_abnormal_skeleton_physiology0.87333572
75MP0005397_hematopoietic_system_phenotyp0.86609601
76MP0001545_abnormal_hematopoietic_system0.86609601
77MP0000015_abnormal_ear_pigmentation0.85899426
78MP0006292_abnormal_olfactory_placode0.84941468
79MP0002998_abnormal_bone_remodeling0.84249478
80MP0000920_abnormal_myelination0.79249542
81MP0003880_abnormal_central_pattern0.77608805
82MP0004130_abnormal_muscle_cell0.77272984
83MP0003045_fibrosis0.76243387
84MP0001348_abnormal_lacrimal_gland0.74574699
85MP0005423_abnormal_somatic_nervous0.72941915
86MP0001663_abnormal_digestive_system0.70291294
87MP0003091_abnormal_cell_migration0.68396831
88MP0000383_abnormal_hair_follicle0.67322380
89MP0009764_decreased_sensitivity_to0.67111118
90MP0001188_hyperpigmentation0.64285747
91MP0001501_abnormal_sleep_pattern0.63423282
92MP0008569_lethality_at_weaning0.62741993
93MP0000604_amyloidosis0.62533897
94MP0000249_abnormal_blood_vessel0.60611391
95MP0003252_abnormal_bile_duct0.59173939
96MP0009765_abnormal_xenobiotic_induced0.59106205
97MP0002735_abnormal_chemical_nociception0.56706965
98MP0002095_abnormal_skin_pigmentation0.56230954
99MP0002019_abnormal_tumor_incidence0.55925753
100MP0005164_abnormal_response_to0.52390158
101MP0002163_abnormal_gland_morphology0.51713556
102MP0003183_abnormal_peptide_metabolism0.49821372
103MP0009115_abnormal_fat_cell0.48160808
104MP0003690_abnormal_glial_cell0.46880182
105MP0003191_abnormal_cellular_cholesterol0.46850612
106MP0005166_decreased_susceptibility_to0.46736755
107MP0002693_abnormal_pancreas_physiology0.46690233
108MP0003795_abnormal_bone_structure0.45885249
109MP0004185_abnormal_adipocyte_glucose0.45310411
110MP0008260_abnormal_autophagy0.44587695
111MP0009763_increased_sensitivity_to0.44567936
112MP0005621_abnormal_cell_physiology0.43919719
113MP0008961_abnormal_basal_metabolism0.43648959
114MP0005390_skeleton_phenotype0.42816363
115MP0002822_catalepsy0.42655344
116MP0001191_abnormal_skin_condition0.42514498
117MP0000609_abnormal_liver_physiology0.42427058
118MP0005379_endocrine/exocrine_gland_phen0.42376732
119MP0008874_decreased_physiological_sensi0.42129616
120MP0001905_abnormal_dopamine_level0.41414885
121MP0005646_abnormal_pituitary_gland0.41177620
122MP0001486_abnormal_startle_reflex0.40679115
123MP0003938_abnormal_ear_development0.40674483
124MP0001216_abnormal_epidermal_layer0.39376122
125MP0001919_abnormal_reproductive_system0.37860967
126MP0005381_digestive/alimentary_phenotyp0.37464703
127MP0002136_abnormal_kidney_physiology0.36641976

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)5.84648181
2Abnormality of T cell number (HP:0011839)5.63696377
3Stomatitis (HP:0010280)4.85460136
4Panhypogammaglobulinemia (HP:0003139)4.76955939
5Agammaglobulinemia (HP:0004432)4.74856225
6Recurrent bronchitis (HP:0002837)4.61031973
7Abnormal delayed hypersensitivity skin test (HP:0002963)4.40522568
8IgM deficiency (HP:0002850)4.37602010
9Abnormality of T cells (HP:0002843)4.24544332
10Chronic otitis media (HP:0000389)4.24167698
11Recurrent sinusitis (HP:0011108)4.18108510
12Recurrent cutaneous fungal infections (HP:0011370)4.17745069
13Chronic mucocutaneous candidiasis (HP:0002728)4.17745069
14Recurrent fungal infections (HP:0002841)4.06513709
15Recurrent viral infections (HP:0004429)4.03955855
16Severe combined immunodeficiency (HP:0004430)3.86698507
17Meningitis (HP:0001287)3.85526604
18IgG deficiency (HP:0004315)3.82861307
19Elevated erythrocyte sedimentation rate (HP:0003565)3.72192648
20Eczematoid dermatitis (HP:0000976)3.68561740
21Chronic diarrhea (HP:0002028)3.66197410
22Lymphopenia (HP:0001888)3.63404577
23Vasculitis (HP:0002633)3.60059620
24Gastrointestinal stroma tumor (HP:0100723)3.54811177
25Inflammation of the large intestine (HP:0002037)3.51566746
26Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.43526181
27Chronic sinusitis (HP:0011109)3.41617535
28Retrobulbar optic neuritis (HP:0100654)3.40956701
29Optic neuritis (HP:0100653)3.40956701
30Combined immunodeficiency (HP:0005387)3.40631866
31Abnormality of cells of the lymphoid lineage (HP:0012140)3.39795891
32B lymphocytopenia (HP:0010976)3.27830972
33Abnormality of B cell number (HP:0010975)3.27830972
34Encephalitis (HP:0002383)3.22178763
35Obstructive lung disease (HP:0006536)3.20463169
36Chronic obstructive pulmonary disease (HP:0006510)3.20463169
37Gastrointestinal inflammation (HP:0004386)3.20165027
38Myositis (HP:0100614)3.18283184
39Mediastinal lymphadenopathy (HP:0100721)3.15280184
40IgA deficiency (HP:0002720)3.13013304
41Nasal polyposis (HP:0100582)3.08949852
42Pulmonary infiltrates (HP:0002113)3.08160527
43Increased IgM level (HP:0003496)3.06853614
44Abnormality of macrophages (HP:0004311)3.03329859
45Hypoplasia of the thymus (HP:0000778)2.95047229
46Abnormality of T cell physiology (HP:0011840)2.91951304
47Abnormality of the fingertips (HP:0001211)2.90985847
48Recurrent abscess formation (HP:0002722)2.81679814
49Autoimmune hemolytic anemia (HP:0001890)2.75502660
50Abnormality of eosinophils (HP:0001879)2.74440276
51Colitis (HP:0002583)2.69562487
52Pustule (HP:0200039)2.67232137
53Slow saccadic eye movements (HP:0000514)2.67016445
54Thyroiditis (HP:0100646)2.65841914
55Eosinophilia (HP:0001880)2.63476533
56Bronchitis (HP:0012387)2.60917073
57Gingivitis (HP:0000230)2.59528054
58Lymphoma (HP:0002665)2.57669601
59Hemoptysis (HP:0002105)2.56167382
60Recurrent skin infections (HP:0001581)2.53243727
61Papilledema (HP:0001085)2.50308298
62Orchitis (HP:0100796)2.48768635
63Recurrent otitis media (HP:0000403)2.45733955
64Fatigue (HP:0012378)2.40379987
65Recurrent gram-negative bacterial infections (HP:0005420)2.38520104
66Emphysema (HP:0002097)2.37608769
67Leukocytosis (HP:0001974)2.37518108
68Spontaneous hematomas (HP:0007420)2.36563179
69Joint swelling (HP:0001386)2.36146912
70Granulocytopenia (HP:0001913)2.29193919
71Abnormality of the prostate (HP:0008775)2.28862637
72Abnormal hair whorl (HP:0010721)2.28025164
73Abnormality of the nasal mucosa (HP:0000433)2.26241792
74Keratoconjunctivitis sicca (HP:0001097)2.25685575
75Viral hepatitis (HP:0006562)2.25674704
76Bronchiectasis (HP:0002110)2.24186451
77Acute hepatic failure (HP:0006554)2.23557481
78Parakeratosis (HP:0001036)2.22181033
79Papilloma (HP:0012740)2.21749101
80Verrucae (HP:0200043)2.21749101
81Cheilitis (HP:0100825)2.20802222
82Subacute progressive viral hepatitis (HP:0006572)2.20448725
83Urticaria (HP:0001025)2.17200483
84Neoplasm of the tracheobronchial system (HP:0100552)2.15687026
85Aplasia/Hypoplasia of the thymus (HP:0010515)2.14869054
86Stomach cancer (HP:0012126)2.10407190
87Anorexia (HP:0002039)2.10351937
88Aplasia cutis congenita (HP:0001057)2.10242145
89Basal cell carcinoma (HP:0002671)2.08743457
90Keratoconjunctivitis (HP:0001096)2.08618218
91Chest pain (HP:0100749)2.07190152
92Osteomyelitis (HP:0002754)2.06724222
93Prolonged bleeding time (HP:0003010)2.06667582
94Restrictive lung disease (HP:0002091)2.05311172
95Increased IgE level (HP:0003212)2.04733544
96Gastrointestinal infarctions (HP:0005244)2.04262686
97Alveolar cell carcinoma (HP:0006519)2.03693743
98Amaurosis fugax (HP:0100576)2.03645603
99Hypergammaglobulinemia (HP:0010702)2.02114929
100Cellulitis (HP:0100658)2.01580236
101Recurrent pneumonia (HP:0006532)2.00509213
102Recurrent bacterial skin infections (HP:0005406)1.99936690
103Microcytic anemia (HP:0001935)1.98006625
104Abnormality of the pleura (HP:0002103)1.96471876
105Arterial thrombosis (HP:0004420)1.92612499
106Gangrene (HP:0100758)1.91750010
107Pulmonary embolism (HP:0002204)1.87480615
108Diplopia (HP:0000651)1.86107127
109Abnormality of binocular vision (HP:0011514)1.86107127
110Hypochromic anemia (HP:0001931)1.86105482
111Abnormality of DNA repair (HP:0003254)1.86010216
112Xerostomia (HP:0000217)1.85578126
113Leukopenia (HP:0001882)1.84201474
114Gingival bleeding (HP:0000225)1.81008921
115Epistaxis (HP:0000421)1.79828993
116Recurrent lower respiratory tract infections (HP:0002783)1.79559459
117Ureteral stenosis (HP:0000071)1.76472834
118Lip pit (HP:0100267)1.76203659
119Autoimmune thrombocytopenia (HP:0001973)1.74126093
120Arthralgia (HP:0002829)1.73806977
121Thrombocytosis (HP:0001894)1.73806215
122Glomerulopathy (HP:0100820)1.72486026
123Sepsis (HP:0100806)1.72118827

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.83193648
2MAP4K15.29111412
3MAP3K143.15243142
4JAK32.98649968
5BLK2.80864810
6ITK2.67419901
7TAOK32.39699363
8IKBKE2.21101845
9MST42.17034755
10MAP3K132.15139509
11ZAP702.08561051
12STK102.01549320
13TYK21.93027855
14GRK61.88681041
15LCK1.85360594
16JAK11.82714574
17NLK1.82028146
18TEC1.81666513
19SYK1.73086102
20IRAK41.70968311
21IKBKB1.64476502
22SIK21.62668425
23TNK21.60309364
24FGFR41.59386656
25PRKCQ1.55440714
26BTK1.52313937
27CAMKK21.51792905
28PRPF4B1.50733269
29CSK1.47982537
30PASK1.46593246
31MAP3K101.39967425
32HCK1.37087337
33CASK1.36654960
34SIK31.36088925
35FGFR31.31433539
36RIPK41.30272847
37FES1.28623388
38MAP2K31.26213010
39CLK11.25840497
40CAMKK11.18927527
41LYN1.13071285
42KIT1.08510848
43NUAK11.07047769
44TBK11.04081509
45CHUK1.03788734
46MKNK21.02982687
47MARK31.02046853
48CDK60.96841059
49IRAK30.96447688
50PIK3CG0.96435852
51PRKCH0.93940094
52PKN10.92291959
53IRAK10.91327383
54CSF1R0.89790385
55CDK40.86762317
56MAPK70.82314907
57ADRBK20.79218714
58MAP3K10.78724368
59BMPR20.78715729
60LRRK20.78314085
61PRKD20.78174925
62MAP3K70.75652235
63EPHB10.75487275
64BRD40.75018258
65TNIK0.74801678
66MAPK110.74257114
67FGR0.73905523
68GRK10.73726770
69GRK70.73210528
70NTRK20.73083750
71TYRO30.72106391
72PIM10.72069693
73YES10.68811857
74STK240.66200975
75MARK20.65272629
76MATK0.59739293
77IRAK20.58100730
78EPHA30.54154593
79INSR0.53388778
80JAK20.51277898
81MAP3K20.50748020
82MAPK120.50661373
83HIPK20.50658585
84FYN0.48360087
85NME20.48232250
86SMG10.47646320
87TGFBR20.47179346
88EEF2K0.46914329
89KSR20.46779211
90TRPM70.45527255
91NEK60.44717064
92RET0.43971826
93CDK30.43384773
94CDK120.43040771
95EGFR0.42970308
96ROCK20.41765694
97MKNK10.41447762
98DYRK1B0.38921652
99ABL10.38183798
100CDK90.37747432
101MAP3K30.37516882
102PDK10.37159751
103MAP3K50.37089367
104RPS6KA50.36576890
105IGF1R0.34961037
106TAOK20.34788368
107ERN10.34392645
108MAP3K110.33998798
109WNK10.32977313
110EIF2AK20.32720081
111RPS6KC10.31903336
112RPS6KL10.31903336
113CAMK1G0.31219127
114SGK20.28910298
115RPS6KA60.28535903
116ALK0.28490212
117CAMK40.28325702
118PDGFRB0.27423205
119STK40.27314674
120PTK2B0.27313299
121DMPK0.27224573
122MAPK40.27036335
123MAP3K120.26447668
124MAPK30.25721046
125FGFR20.25286005
126SGK10.25232198
127RAF10.24058479
128MAPKAPK20.23988217
129MELK0.23312839
130TAOK10.22166687
131CSNK1A1L0.21063331
132DYRK1A0.20035478
133SGK30.18744753

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.00310084
2Graft-versus-host disease_Homo sapiens_hsa053323.38676612
3T cell receptor signaling pathway_Homo sapiens_hsa046603.24525079
4Allograft rejection_Homo sapiens_hsa053303.16742295
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053213.06836121
6Autoimmune thyroid disease_Homo sapiens_hsa053202.79987391
7Intestinal immune network for IgA production_Homo sapiens_hsa046722.79499704
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.65997718
9Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.54437441
10Hematopoietic cell lineage_Homo sapiens_hsa046402.46549310
11Measles_Homo sapiens_hsa051622.43730681
12B cell receptor signaling pathway_Homo sapiens_hsa046622.37864275
13Leishmaniasis_Homo sapiens_hsa051401.80480005
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.73357097
15Osteoclast differentiation_Homo sapiens_hsa043801.70176584
16Type I diabetes mellitus_Homo sapiens_hsa049401.68355782
17Jak-STAT signaling pathway_Homo sapiens_hsa046301.64887112
18Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.59370433
19Asthma_Homo sapiens_hsa053101.58226960
20Antigen processing and presentation_Homo sapiens_hsa046121.56018719
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.49786658
22Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.47352159
23Chemokine signaling pathway_Homo sapiens_hsa040621.42205210
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.41904310
25Viral myocarditis_Homo sapiens_hsa054161.29490850
26Herpes simplex infection_Homo sapiens_hsa051681.22720840
27Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.17096520
28Toll-like receptor signaling pathway_Homo sapiens_hsa046201.14160551
29Malaria_Homo sapiens_hsa051441.07006677
30Toxoplasmosis_Homo sapiens_hsa051451.05135413
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.04643258
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03410609
33Rheumatoid arthritis_Homo sapiens_hsa053231.00830964
34Hepatitis B_Homo sapiens_hsa051610.98537844
35Influenza A_Homo sapiens_hsa051640.94912858
36TNF signaling pathway_Homo sapiens_hsa046680.90304446
37Leukocyte transendothelial migration_Homo sapiens_hsa046700.90286319
38Ribosome_Homo sapiens_hsa030100.90263977
39Acute myeloid leukemia_Homo sapiens_hsa052210.90199221
40Endometrial cancer_Homo sapiens_hsa052130.88930275
41Dorso-ventral axis formation_Homo sapiens_hsa043200.87748283
42Tuberculosis_Homo sapiens_hsa051520.87565230
43Non-homologous end-joining_Homo sapiens_hsa034500.84116855
44Shigellosis_Homo sapiens_hsa051310.81679701
45African trypanosomiasis_Homo sapiens_hsa051430.81424271
46Phosphatidylinositol signaling system_Homo sapiens_hsa040700.76437202
47HTLV-I infection_Homo sapiens_hsa051660.75944919
48Transcriptional misregulation in cancer_Homo sapiens_hsa052020.75097970
49Platelet activation_Homo sapiens_hsa046110.75036000
50Hepatitis C_Homo sapiens_hsa051600.71832315
51mTOR signaling pathway_Homo sapiens_hsa041500.71742794
52Epstein-Barr virus infection_Homo sapiens_hsa051690.70602983
53Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70032970
54Thyroid cancer_Homo sapiens_hsa052160.68978676
55AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68739397
56Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.67175931
57MAPK signaling pathway_Homo sapiens_hsa040100.66405778
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65707134
59Pancreatic cancer_Homo sapiens_hsa052120.63769758
60Apoptosis_Homo sapiens_hsa042100.62783452
61Glioma_Homo sapiens_hsa052140.62569255
62Prolactin signaling pathway_Homo sapiens_hsa049170.60896612
63Pertussis_Homo sapiens_hsa051330.60521302
64Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60130740
65Salmonella infection_Homo sapiens_hsa051320.58171366
66Staphylococcus aureus infection_Homo sapiens_hsa051500.57013309
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56661566
68Long-term potentiation_Homo sapiens_hsa047200.55591702
69HIF-1 signaling pathway_Homo sapiens_hsa040660.54704950
70Fanconi anemia pathway_Homo sapiens_hsa034600.51049855
71Sphingolipid signaling pathway_Homo sapiens_hsa040710.49924383
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49847374
73Inositol phosphate metabolism_Homo sapiens_hsa005620.49573354
74Insulin resistance_Homo sapiens_hsa049310.49036602
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.47768118
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47490424
77Systemic lupus erythematosus_Homo sapiens_hsa053220.46978039
78Morphine addiction_Homo sapiens_hsa050320.46820173
79Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46295933
80Legionellosis_Homo sapiens_hsa051340.46203947
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.45746734
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44987969
83Chronic myeloid leukemia_Homo sapiens_hsa052200.44311117
84Choline metabolism in cancer_Homo sapiens_hsa052310.43746878
85Ras signaling pathway_Homo sapiens_hsa040140.43746618
86Endocytosis_Homo sapiens_hsa041440.41816118
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39900137
88Viral carcinogenesis_Homo sapiens_hsa052030.39764350
89GnRH signaling pathway_Homo sapiens_hsa049120.39509746
90Rap1 signaling pathway_Homo sapiens_hsa040150.39269322
91Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37898080
92Nicotine addiction_Homo sapiens_hsa050330.37537196
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37419401
94MicroRNAs in cancer_Homo sapiens_hsa052060.36892695
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36351759
96Type II diabetes mellitus_Homo sapiens_hsa049300.36201727
97Prostate cancer_Homo sapiens_hsa052150.36169817
98Colorectal cancer_Homo sapiens_hsa052100.35993193
99VEGF signaling pathway_Homo sapiens_hsa043700.35649873
100Spliceosome_Homo sapiens_hsa030400.34618832
101Serotonergic synapse_Homo sapiens_hsa047260.34090773
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.34020140
103Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33608144
104Renal cell carcinoma_Homo sapiens_hsa052110.32926240
105ErbB signaling pathway_Homo sapiens_hsa040120.30709719
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.30314933
107Regulation of autophagy_Homo sapiens_hsa041400.30086066
108Phagosome_Homo sapiens_hsa041450.29993378
109Sphingolipid metabolism_Homo sapiens_hsa006000.29812550
110Glutamatergic synapse_Homo sapiens_hsa047240.29605657
111Renin secretion_Homo sapiens_hsa049240.29026853
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.28503180
113Taste transduction_Homo sapiens_hsa047420.28388297
114Calcium signaling pathway_Homo sapiens_hsa040200.27865319
115RNA degradation_Homo sapiens_hsa030180.27338121
116Axon guidance_Homo sapiens_hsa043600.27309592
117FoxO signaling pathway_Homo sapiens_hsa040680.26231414
118Long-term depression_Homo sapiens_hsa047300.24843138
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24706034
120Non-small cell lung cancer_Homo sapiens_hsa052230.23970059
121Notch signaling pathway_Homo sapiens_hsa043300.23940606
122Small cell lung cancer_Homo sapiens_hsa052220.23599218
123Salivary secretion_Homo sapiens_hsa049700.23306936

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