GPR171

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine deamination (GO:0009972)7.80987649
2cytidine metabolic process (GO:0046087)7.80987649
3cytidine catabolic process (GO:0006216)7.80987649
4pyrimidine ribonucleoside catabolic process (GO:0046133)7.03478379
5regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.38328073
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.61968579
7positive regulation of gamma-delta T cell activation (GO:0046645)5.23971535
8positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.18490252
9activated T cell proliferation (GO:0050798)5.16563864
10regulation of lymphocyte chemotaxis (GO:1901623)5.12405014
11regulation of chronic inflammatory response (GO:0002676)5.10440627
12interferon-gamma production (GO:0032609)4.81405211
13antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.79658010
14antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.79658010
15mature B cell differentiation involved in immune response (GO:0002313)4.76317377
16positive T cell selection (GO:0043368)4.68490636
17regulation of T cell tolerance induction (GO:0002664)4.66785941
18negative regulation by host of viral transcription (GO:0043922)4.61783776
19regulation of T cell chemotaxis (GO:0010819)4.61774809
20positive regulation of T cell chemotaxis (GO:0010820)4.61774809
21ribosomal small subunit assembly (GO:0000028)4.59920564
22antigen processing and presentation of endogenous antigen (GO:0019883)4.59097972
23defense response to protozoan (GO:0042832)4.43058200
24regulation of cell killing (GO:0031341)4.43035731
25regulation of interleukin-2 biosynthetic process (GO:0045076)4.42249728
26positive regulation of calcium-mediated signaling (GO:0050850)4.42037673
27positive regulation of tolerance induction (GO:0002645)4.33200649
28negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.25215141
29negative regulation of cell killing (GO:0031342)4.25215141
30mature B cell differentiation (GO:0002335)4.21510680
31positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.19551532
32response to protozoan (GO:0001562)4.19375877
33positive regulation of lymphocyte migration (GO:2000403)4.15432637
34lymph node development (GO:0048535)4.12466507
35positive regulation of B cell differentiation (GO:0045579)4.12401189
36regulation of gamma-delta T cell differentiation (GO:0045586)4.06568880
37mast cell activation (GO:0045576)4.03904070
38cellular response to interleukin-15 (GO:0071350)4.00881648
39thymic T cell selection (GO:0045061)4.00143956
40regulation of interleukin-12 biosynthetic process (GO:0045075)3.93877946
41regulation of tolerance induction (GO:0002643)3.90843555
42regulation of B cell differentiation (GO:0045577)3.90602303
43lymphocyte chemotaxis (GO:0048247)3.90167626
44regulation of B cell receptor signaling pathway (GO:0050855)3.86899074
45response to interleukin-15 (GO:0070672)3.81243377
46definitive hemopoiesis (GO:0060216)3.79578652
47regulation of gamma-delta T cell activation (GO:0046643)3.77632830
48T cell selection (GO:0045058)3.71453572
49negative regulation of T cell apoptotic process (GO:0070233)3.69598988
50negative regulation of viral genome replication (GO:0045071)3.67541705
51negative regulation of T cell mediated immunity (GO:0002710)3.67450210
52positive regulation of lymphocyte mediated immunity (GO:0002708)3.64120619
53mucosal-associated lymphoid tissue development (GO:0048537)3.62330274
54Peyers patch development (GO:0048541)3.62330274
55regulation of T cell receptor signaling pathway (GO:0050856)3.57315099
56positive regulation of isotype switching (GO:0045830)3.49584459
57immunoglobulin mediated immune response (GO:0016064)3.47603524
58T cell receptor signaling pathway (GO:0050852)3.47046235
59B cell receptor signaling pathway (GO:0050853)3.46405550
60positive regulation of T cell mediated cytotoxicity (GO:0001916)3.46024121
61dosage compensation (GO:0007549)3.43495462
62cellular response to type I interferon (GO:0071357)3.42595187
63type I interferon signaling pathway (GO:0060337)3.42595187
64response to type I interferon (GO:0034340)3.42120693
65negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.39883656
66regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.39484214
67myeloid dendritic cell activation (GO:0001773)3.39412701
68regulation of activation of Janus kinase activity (GO:0010533)3.38964648
69regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.38946235
70regulation of T cell mediated cytotoxicity (GO:0001914)3.38271069
71T cell homeostasis (GO:0043029)3.36630244
72response to interferon-beta (GO:0035456)3.35794416
73regulation of lymphocyte migration (GO:2000401)3.34631394
74eosinophil chemotaxis (GO:0048245)3.34388635
75negative T cell selection (GO:0043383)3.33567609
76pyrimidine nucleoside catabolic process (GO:0046135)3.32031214
77antigen processing and presentation via MHC class Ib (GO:0002475)3.32014205
78Arp2/3 complex-mediated actin nucleation (GO:0034314)3.31612252
79regulation of isotype switching to IgG isotypes (GO:0048302)3.28512984
80negative thymic T cell selection (GO:0045060)3.27916158
81cellular defense response (GO:0006968)3.26777710
82positive regulation of interleukin-17 production (GO:0032740)3.24133566
83lymphocyte costimulation (GO:0031294)3.23227302
84T cell migration (GO:0072678)3.23190703
85CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.22253285
86positive regulation of interleukin-8 secretion (GO:2000484)3.22064409
87T cell costimulation (GO:0031295)3.20148084
88regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.19996463
89regulation of calcium-mediated signaling (GO:0050848)3.19987838
90lymphocyte migration (GO:0072676)3.18408016
91positive regulation of leukocyte mediated immunity (GO:0002705)3.17935270
92antigen receptor-mediated signaling pathway (GO:0050851)3.17088364
93positive regulation of DNA recombination (GO:0045911)3.16086829
94positive regulation of T cell migration (GO:2000406)3.13221096
95regulation of lymphocyte mediated immunity (GO:0002706)3.11886459
96viral transcription (GO:0019083)3.10438001
97positive regulation of humoral immune response (GO:0002922)3.09590008
98positive regulation of defense response to virus by host (GO:0002230)3.08196246
99cellular response to interferon-beta (GO:0035458)3.08073563
100interferon-gamma-mediated signaling pathway (GO:0060333)3.07392016
101alpha-beta T cell activation (GO:0046631)3.06315213
102positive regulation of T cell mediated immunity (GO:0002711)3.05948256
103T cell mediated immunity (GO:0002456)3.05360637
104leukocyte aggregation (GO:0070486)3.04993504
105negative regulation of viral transcription (GO:0032897)3.04921693
106lymphoid progenitor cell differentiation (GO:0002320)3.04029140
107eosinophil migration (GO:0072677)3.00821831
108megakaryocyte development (GO:0035855)3.00357169
109mast cell degranulation (GO:0043303)2.98729885
110mast cell activation involved in immune response (GO:0002279)2.98729885
111positive regulation of interleukin-10 production (GO:0032733)2.97565360
112translational termination (GO:0006415)2.97410027
113regulation of alpha-beta T cell proliferation (GO:0046640)2.97185565
114positive regulation of immunoglobulin mediated immune response (GO:0002891)2.96257930
115positive regulation of B cell mediated immunity (GO:0002714)2.96257930
116regulation of T cell migration (GO:2000404)2.96147058
117positive regulation of alpha-beta T cell proliferation (GO:0046641)2.95077348
118leukocyte homeostasis (GO:0001776)2.93751848
119negative regulation of adaptive immune response (GO:0002820)2.92923778
120B cell mediated immunity (GO:0019724)2.87736299
121alpha-beta T cell differentiation (GO:0046632)2.85693794
122platelet dense granule organization (GO:0060155)2.84337230
123positive regulation of granulocyte differentiation (GO:0030854)2.83938057
124myeloid dendritic cell differentiation (GO:0043011)2.83499192
125CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.82400434
126regulation of response to interferon-gamma (GO:0060330)2.81642606
127positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.81614362
128natural killer cell activation (GO:0030101)2.81473247
129negative regulation of phagocytosis (GO:0050765)2.80691048
130positive regulation of natural killer cell mediated immunity (GO:0002717)2.78726206
131positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.78726206
132regulation of leukocyte mediated cytotoxicity (GO:0001910)2.78260871
133positive regulation of macrophage differentiation (GO:0045651)2.77916582
134regulation of B cell mediated immunity (GO:0002712)2.76966474
135ribosomal small subunit biogenesis (GO:0042274)2.75370162
136cellular response to exogenous dsRNA (GO:0071360)2.75148146
137T cell differentiation (GO:0030217)2.75145524
138regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.75031476
139regulation of isotype switching (GO:0045191)2.74978204
140positive regulation of interferon-gamma production (GO:0032729)2.74702376
141positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.74621830
142regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.74600675
143regulation of natural killer cell mediated immunity (GO:0002715)2.74600675
144positive regulation of B cell activation (GO:0050871)2.73133400
145germinal center formation (GO:0002467)2.72932296
146positive thymic T cell selection (GO:0045059)2.72584734
147lymphocyte homeostasis (GO:0002260)2.72073946
148positive regulation of cell killing (GO:0031343)2.70832674
149response to interferon-alpha (GO:0035455)2.69871799
150CD4-positive, alpha-beta T cell activation (GO:0035710)2.69626574
151NIK/NF-kappaB signaling (GO:0038061)2.68344688
152DNA deamination (GO:0045006)2.67740154
153positive regulation of natural killer cell differentiation (GO:0032825)2.67472817
154regulation of regulatory T cell differentiation (GO:0045589)2.66206899

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.12026857
2E2F7_22180533_ChIP-Seq_HELA_Human4.85771682
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.85671965
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.37332965
5* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.14144189
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.02289001
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.73022897
8BP1_19119308_ChIP-ChIP_Hs578T_Human3.69778934
9IRF8_21731497_ChIP-ChIP_J774_Mouse3.64584259
10SCL_19346495_ChIP-Seq_HPC-7_Human3.29149548
11STAT4_19710469_ChIP-ChIP_TH1__Mouse3.15048159
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.14728583
13RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.97657575
14SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.94022494
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.89376003
16* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.85893328
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79131227
18NOTCH1_21737748_ChIP-Seq_TLL_Human2.70153594
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.60889918
20FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.51343811
21RUNX_20019798_ChIP-Seq_JUKART_Human2.50932259
22* MYB_26560356_Chip-Seq_TH2_Human2.47809540
23SPI1_23547873_ChIP-Seq_NB4_Human2.39951683
24MYB_21317192_ChIP-Seq_ERMYB_Mouse2.39007379
25SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.33103281
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.31140526
27IRF8_27001747_Chip-Seq_BMDM_Mouse2.29453986
28MYC_22102868_ChIP-Seq_BL_Human2.26338558
29TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.26128405
30* MYB_26560356_Chip-Seq_TH1_Human2.13558780
31NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.12580791
32CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.07521583
33MAF_26560356_Chip-Seq_TH1_Human2.05548457
34FLI1_27457419_Chip-Seq_LIVER_Mouse2.01463565
35VDR_21846776_ChIP-Seq_THP-1_Human1.99534383
36RUNX1_22412390_ChIP-Seq_EML_Mouse1.96344764
37* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.94469893
38MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.90152312
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.89500371
40LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.87276457
41EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.82553323
42VDR_24763502_ChIP-Seq_THP-1_Human1.81207034
43SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.80987338
44LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.78814976
45ERG_20887958_ChIP-Seq_HPC-7_Mouse1.76306899
46MYC_18555785_ChIP-Seq_MESCs_Mouse1.74384584
47TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.69010911
48E2F4_17652178_ChIP-ChIP_JURKAT_Human1.68572467
49UTX_26944678_Chip-Seq_JUKART_Human1.67521263
50BRD4_27068464_Chip-Seq_AML-cells_Mouse1.67054367
51VDR_23849224_ChIP-Seq_CD4+_Human1.66948762
52FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63470289
53NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.58247535
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.56909189
55GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.54576831
56PCGF2_27294783_Chip-Seq_NPCs_Mouse1.50101121
57* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.48096854
58VDR_22108803_ChIP-Seq_LS180_Human1.47308539
59* GATA3_27048872_Chip-Seq_THYMUS_Human1.46957697
60SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44861541
61TCF7_22412390_ChIP-Seq_EML_Mouse1.42279563
62FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.40727658
63* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.38721972
64NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.36570576
65* FOXP3_21729870_ChIP-Seq_TREG_Human1.34594952
66EST1_17652178_ChIP-ChIP_JURKAT_Human1.32274308
67GATA1_22025678_ChIP-Seq_K562_Human1.31401669
68GABP_17652178_ChIP-ChIP_JURKAT_Human1.31388633
69E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30539744
70GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.29816667
71* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.29413868
72* MAF_26560356_Chip-Seq_TH2_Human1.27859970
73SPI1_23127762_ChIP-Seq_K562_Human1.26971446
74RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.26610245
75PU_27001747_Chip-Seq_BMDM_Mouse1.25708940
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.19837578
77MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18638323
78CIITA_25753668_ChIP-Seq_RAJI_Human1.18581802
79ELK1_19687146_ChIP-ChIP_HELA_Human1.18562412
80* GATA3_26560356_Chip-Seq_TH2_Human1.14369952
81TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.12374448
82RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08206877
83CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07352010
84HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.07319347
85MYC_18358816_ChIP-ChIP_MESCs_Mouse1.07051984
86SRF_21415370_ChIP-Seq_HL-1_Mouse1.05760271
87ETS1_22383799_ChIP-Seq_G1ME_Mouse1.03925821
88NFE2_27457419_Chip-Seq_LIVER_Mouse1.03189644
89GATA3_26560356_Chip-Seq_TH1_Human1.02444372
90CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01581237
91PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01299611
92E2F1_21310950_ChIP-Seq_MCF-7_Human1.00966163
93SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00237128
94JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.99229002
95MYC_19030024_ChIP-ChIP_MESCs_Mouse0.98818569
96STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.98304131
97PU.1_20513432_ChIP-Seq_Bcells_Mouse0.97936537
98FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.97202518
99CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95012882
100TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94664083
101BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.92878836
102XRN2_22483619_ChIP-Seq_HELA_Human0.92032414
103GATA1_19941827_ChIP-Seq_MEL_Mouse0.91425162
104KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.90327223
105MYC_19079543_ChIP-ChIP_MESCs_Mouse0.88742233
106HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.88421573
107HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.87266462
108ETS1_20019798_ChIP-Seq_JURKAT_Human0.84361022
109FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84047397
110KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.82251831
111NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.81653066
112TP53_22573176_ChIP-Seq_HFKS_Human0.80870649
113PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80324484
114CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80225095
115PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.79999979
116EZH2_27294783_Chip-Seq_NPCs_Mouse0.79903784
117GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.77783862
118PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77421062
119VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.77340280
120TP63_19390658_ChIP-ChIP_HaCaT_Human0.75273504
121SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.75265569
122PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.74951091
123FOXA1_27270436_Chip-Seq_PROSTATE_Human0.74721334
124FOXA1_25329375_ChIP-Seq_VCAP_Human0.74721334
125EGR1_23403033_ChIP-Seq_LIVER_Mouse0.74416916
126PRDM14_20953172_ChIP-Seq_ESCs_Human0.73229372
127RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.71683039
128CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.71451224
129EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.70936898
130CRX_20693478_ChIP-Seq_RETINA_Mouse0.70924119
131EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.70719941
132FOXH1_21741376_ChIP-Seq_EPCs_Human0.69020645
133SMRT_27268052_Chip-Seq_Bcells_Human0.68530308
134VDR_24787735_ChIP-Seq_THP-1_Human0.68437827
135CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.67455073
136CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.66272686
137FOXA1_21572438_ChIP-Seq_LNCaP_Human0.64605529
138CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.64550994
139SMAD1_18555785_Chip-Seq_ESCs_Mouse0.64539195

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.72922514
2MP0005671_abnormal_response_to4.38365804
3MP0009785_altered_susceptibility_to3.60475925
4MP0000685_abnormal_immune_system3.31614276
5MP0003763_abnormal_thymus_physiology3.30439272
6MP0002396_abnormal_hematopoietic_system3.29200543
7MP0001800_abnormal_humoral_immune3.05737006
8MP0002148_abnormal_hypersensitivity_rea2.92832275
9MP0005025_abnormal_response_to2.89255035
10MP0005000_abnormal_immune_tolerance2.84068293
11MP0002723_abnormal_immune_serum2.74946644
12MP0002452_abnormal_antigen_presenting2.73513496
13MP0005387_immune_system_phenotype2.72588446
14MP0001790_abnormal_immune_system2.72588446
15MP0002420_abnormal_adaptive_immunity2.70816934
16MP0001819_abnormal_immune_cell2.69246005
17MP0003436_decreased_susceptibility_to2.66242285
18MP0002398_abnormal_bone_marrow2.59622136
19MP0008057_abnormal_DNA_replication2.41832901
20MP0005464_abnormal_platelet_physiology2.32369882
21MP0004808_abnormal_hematopoietic_stem2.31691934
22MP0000716_abnormal_immune_system2.29552439
23MP0002166_altered_tumor_susceptibility2.29483302
24MP0002419_abnormal_innate_immunity2.26817231
25MP0000689_abnormal_spleen_morphology2.20767818
26MP0002006_tumorigenesis2.16994790
27MP0006082_CNS_inflammation2.12448336
28MP0001853_heart_inflammation2.12370801
29MP0005397_hematopoietic_system_phenotyp2.08954195
30MP0001545_abnormal_hematopoietic_system2.08954195
31MP0002722_abnormal_immune_system2.07804928
32MP0002405_respiratory_system_inflammati2.07468540
33MP0009333_abnormal_splenocyte_physiolog2.07233280
34MP0001873_stomach_inflammation2.03010541
35MP0010155_abnormal_intestine_physiology2.01563698
36MP0003724_increased_susceptibility_to1.98788181
37MP0002429_abnormal_blood_cell1.96671413
38MP0003866_abnormal_defecation1.93894612
39MP0000703_abnormal_thymus_morphology1.80094537
40MP0002163_abnormal_gland_morphology1.74373457
41MP0000490_abnormal_crypts_of1.73368401
42MP0005174_abnormal_tail_pigmentation1.72355334
43MP0005075_abnormal_melanosome_morpholog1.67185514
44MP0001845_abnormal_inflammatory_respons1.65624250
45MP0000465_gastrointestinal_hemorrhage1.58189137
46MP0000569_abnormal_digit_pigmentation1.53301434
47MP0008469_abnormal_protein_level1.31946715
48MP0008007_abnormal_cellular_replicative1.30151851
49MP0004947_skin_inflammation1.29713074
50MP0000858_altered_metastatic_potential1.24075389
51MP0010094_abnormal_chromosome_stability1.22503651
52MP0003448_altered_tumor_morphology1.22298668
53MP0002138_abnormal_hepatobiliary_system1.18243276
54MP0003303_peritoneal_inflammation1.16624088
55MP0001501_abnormal_sleep_pattern1.13919581
56MP0002019_abnormal_tumor_incidence1.13200706
57MP0004510_myositis1.12589179
58MP0002095_abnormal_skin_pigmentation1.10720336
59MP0002277_abnormal_respiratory_mucosa1.09613140
60MP0003300_gastrointestinal_ulcer1.09214723
61MP0008058_abnormal_DNA_repair1.06874373
62MP0008872_abnormal_physiological_respon1.03780842
63MP0002693_abnormal_pancreas_physiology1.02798068
64MP0003693_abnormal_embryo_hatching1.02103113
65MP0001919_abnormal_reproductive_system1.01416165
66MP0009764_decreased_sensitivity_to0.99009099
67MP0003787_abnormal_imprinting0.97561076
68MP0002933_joint_inflammation0.96143979
69MP0005310_abnormal_salivary_gland0.94810235
70MP0005379_endocrine/exocrine_gland_phen0.93414134
71MP0005645_abnormal_hypothalamus_physiol0.93398845
72MP0001533_abnormal_skeleton_physiology0.92279575
73MP0003646_muscle_fatigue0.91868564
74MP0003077_abnormal_cell_cycle0.87957534
75MP0001851_eye_inflammation0.87357450
76MP0000015_abnormal_ear_pigmentation0.86482009
77MP0003868_abnormal_feces_composition0.85413905
78MP0009278_abnormal_bone_marrow0.85155936
79MP0001968_abnormal_touch/_nociception0.84062021
80MP0009763_increased_sensitivity_to0.83552727
81MP0010307_abnormal_tumor_latency0.83490163
82MP0002009_preneoplasia0.81127943
83MP0003943_abnormal_hepatobiliary_system0.79820163
84MP0000343_altered_response_to0.78146658
85MP0009765_abnormal_xenobiotic_induced0.77628024
86MP0002132_abnormal_respiratory_system0.77197003
87MP0003172_abnormal_lysosome_physiology0.77024865
88MP0008877_abnormal_DNA_methylation0.76913537
89MP0001348_abnormal_lacrimal_gland0.76203098
90MP0001663_abnormal_digestive_system0.76031870
91MP0006054_spinal_hemorrhage0.74001789
92MP0002102_abnormal_ear_morphology0.73430866
93MP0000313_abnormal_cell_death0.72874419
94MP0001986_abnormal_taste_sensitivity0.72347150
95MP0002234_abnormal_pharynx_morphology0.72246974
96MP0002877_abnormal_melanocyte_morpholog0.71989146
97MP0004742_abnormal_vestibular_system0.71894972
98MP0003656_abnormal_erythrocyte_physiolo0.70544641
99MP0003186_abnormal_redox_activity0.67684178
100MP0003045_fibrosis0.67448100
101MP0002928_abnormal_bile_duct0.66474837
102MP0002736_abnormal_nociception_after0.66446115
103MP0002876_abnormal_thyroid_physiology0.64549708
104MP0001765_abnormal_ion_homeostasis0.61915301
105MP0004145_abnormal_muscle_electrophysio0.58790379
106MP0001502_abnormal_circadian_rhythm0.56811612
107MP0003191_abnormal_cellular_cholesterol0.56595778
108MP0002168_other_aberrant_phenotype0.56320615
109MP0000613_abnormal_salivary_gland0.55872008
110MP0005166_decreased_susceptibility_to0.55750919
111MP0008873_increased_physiological_sensi0.55284576
112MP0004957_abnormal_blastocyst_morpholog0.55261397
113MP0009643_abnormal_urine_homeostasis0.54259473
114MP0004381_abnormal_hair_follicle0.53714204
115MP0002998_abnormal_bone_remodeling0.53684908
116MP0003111_abnormal_nucleus_morphology0.52906869
117MP0000477_abnormal_intestine_morphology0.52787916
118MP0004142_abnormal_muscle_tone0.52537504
119MP0002136_abnormal_kidney_physiology0.52339964
120MP0005584_abnormal_enzyme/coenzyme_acti0.52305272
121MP0003075_altered_response_to0.50808812
122MP0008995_early_reproductive_senescence0.49246391
123MP0005636_abnormal_mineral_homeostasis0.49058484
124MP0003786_premature_aging0.47695691
125MP0000372_irregular_coat_pigmentation0.47677313
126MP0006292_abnormal_olfactory_placode0.47299406
127MP0005408_hypopigmentation0.46835002
128MP0000371_diluted_coat_color0.46798940
129MP0000920_abnormal_myelination0.46612959
130MP0005389_reproductive_system_phenotype0.46552250
131MP0003183_abnormal_peptide_metabolism0.46416283
132MP0005165_increased_susceptibility_to0.43490580
133MP0001905_abnormal_dopamine_level0.42780242

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)5.31669699
2Myositis (HP:0100614)5.14380550
3Chronic otitis media (HP:0000389)4.60608696
4Thrombocytosis (HP:0001894)4.49892440
5IgM deficiency (HP:0002850)4.25720235
6Recurrent abscess formation (HP:0002722)4.19986597
7Recurrent bronchitis (HP:0002837)4.11217437
8Recurrent bacterial skin infections (HP:0005406)3.79872215
9Recurrent viral infections (HP:0004429)3.78569466
10Retrobulbar optic neuritis (HP:0100654)3.74140726
11Optic neuritis (HP:0100653)3.74140726
12T lymphocytopenia (HP:0005403)3.67807791
13Recurrent fungal infections (HP:0002841)3.65525958
14Aplastic anemia (HP:0001915)3.63907991
15Orchitis (HP:0100796)3.56157242
16Abnormality of T cells (HP:0002843)3.51380278
17Abnormality of T cell number (HP:0011839)3.49265467
18IgG deficiency (HP:0004315)3.47333255
19Meningitis (HP:0001287)3.46371181
20Eczematoid dermatitis (HP:0000976)3.43195477
21Panhypogammaglobulinemia (HP:0003139)3.39953177
22Abnormality of the prostate (HP:0008775)3.28423725
23Joint swelling (HP:0001386)3.26577428
24Gangrene (HP:0100758)3.26162902
25Agammaglobulinemia (HP:0004432)3.23918788
26Encephalitis (HP:0002383)3.18808161
27Stomatitis (HP:0010280)3.15627937
28Abnormality of B cell number (HP:0010975)3.11793587
29B lymphocytopenia (HP:0010976)3.11793587
30Abnormality of T cell physiology (HP:0011840)3.07752404
31Recurrent cutaneous fungal infections (HP:0011370)3.07481402
32Chronic mucocutaneous candidiasis (HP:0002728)3.07481402
33Vasculitis (HP:0002633)3.00711378
34Prolonged bleeding time (HP:0003010)3.00400098
35Recurrent skin infections (HP:0001581)2.98163330
36Eosinophilia (HP:0001880)2.96642585
37Papilledema (HP:0001085)2.95066723
38Amaurosis fugax (HP:0100576)2.93136641
39Cellulitis (HP:0100658)2.93062272
40Mediastinal lymphadenopathy (HP:0100721)2.92727749
41Autoimmune hemolytic anemia (HP:0001890)2.91375950
42Petechiae (HP:0000967)2.89768097
43Epistaxis (HP:0000421)2.87958563
44Thyroiditis (HP:0100646)2.84759494
45Arterial thrombosis (HP:0004420)2.83361397
46Severe combined immunodeficiency (HP:0004430)2.80390021
47Abnormality of macrophages (HP:0004311)2.79124756
48Lymphoma (HP:0002665)2.78836809
49Lymphopenia (HP:0001888)2.78440570
50Pulmonary embolism (HP:0002204)2.77488588
51Birth length less than 3rd percentile (HP:0003561)2.76453387
52Chronic diarrhea (HP:0002028)2.72320950
53Abnormal delayed hypersensitivity skin test (HP:0002963)2.70832591
54Keratoconjunctivitis sicca (HP:0001097)2.70475276
55Acute myeloid leukemia (HP:0004808)2.67800060
56Hypoplasia of the thymus (HP:0000778)2.66397092
57Obstructive lung disease (HP:0006536)2.66306188
58Chronic obstructive pulmonary disease (HP:0006510)2.66306188
59Autoimmune thrombocytopenia (HP:0001973)2.64130563
60Abnormality of the fingertips (HP:0001211)2.63842580
61Muscle fiber atrophy (HP:0100295)2.63174835
62Neonatal hypoglycemia (HP:0001998)2.63039223
63Abnormality of cells of the lymphoid lineage (HP:0012140)2.61296673
64Recurrent sinusitis (HP:0011108)2.57652447
65Nasal polyposis (HP:0100582)2.55122423
66Granulocytopenia (HP:0001913)2.55002451
67Gingival bleeding (HP:0000225)2.54664504
68Combined immunodeficiency (HP:0005387)2.48702694
69IgA deficiency (HP:0002720)2.46671251
70Type 2 muscle fiber atrophy (HP:0003554)2.45783971
71Keratoconjunctivitis (HP:0001096)2.44523577
72Reticulocytopenia (HP:0001896)2.41915682
73Abnormal number of erythroid precursors (HP:0012131)2.41709742
74Anorexia (HP:0002039)2.41335393
75Asplenia (HP:0001746)2.41077334
76Hemoptysis (HP:0002105)2.40590547
77Abnormality of cells of the erythroid lineage (HP:0012130)2.39088538
78Keratitis (HP:0000491)2.38329408
79Chest pain (HP:0100749)2.37681487
80Pulmonary infiltrates (HP:0002113)2.37274604
81Gastrointestinal stroma tumor (HP:0100723)2.34401009
82Polyneuropathy (HP:0001271)2.33426983
83Abnormality of the nasal mucosa (HP:0000433)2.32944278
84Reduced antithrombin III activity (HP:0001976)2.31580809
85Leukocytosis (HP:0001974)2.31441644
86Abnormality of the pericardium (HP:0001697)2.27578862
87Hypoproteinemia (HP:0003075)2.27154481
88Inflammation of the large intestine (HP:0002037)2.24772156
89Chronic sinusitis (HP:0011109)2.24351738
90Glomerulopathy (HP:0100820)2.23659897
91Acute hepatic failure (HP:0006554)2.22712557
92Gastrointestinal inflammation (HP:0004386)2.20748919
93Bronchitis (HP:0012387)2.20635631
94Ureteral stenosis (HP:0000071)2.17994413
95Abnormality of eosinophils (HP:0001879)2.16469982
96Myelodysplasia (HP:0002863)2.14908646
97Acute lymphatic leukemia (HP:0006721)2.14457135
98Hypergammaglobulinemia (HP:0010702)2.13955113
99Increased IgM level (HP:0003496)2.12555054
100Gastrointestinal infarctions (HP:0005244)2.12463819
101Interstitial pulmonary disease (HP:0006530)2.12324900
102Aplasia/Hypoplasia of the spleen (HP:0010451)2.11517019
103Type I transferrin isoform profile (HP:0003642)2.11121591
104Pustule (HP:0200039)2.10412023
105Ureteral obstruction (HP:0006000)2.10165030
1063-Methylglutaconic aciduria (HP:0003535)2.05339326
107Hypoalbuminemia (HP:0003073)2.04825233
108Abnormal albumin level (HP:0012116)2.04825233
109Pancytopenia (HP:0001876)2.04551876
110Basal ganglia calcification (HP:0002135)2.04040551
111Thrombophlebitis (HP:0004418)2.00590522
112Spontaneous hematomas (HP:0007420)2.00053300
113Recurrent gram-negative bacterial infections (HP:0005420)1.99153254
114Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.96876028
115Abnormality of the pleura (HP:0002103)1.95917356
116Pancreatitis (HP:0001733)1.94962653
117Microcytic anemia (HP:0001935)1.93591843
118Skin rash (HP:0000988)1.92028868
119Recurrent pneumonia (HP:0006532)1.91226260
120Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.91020138
121Congenital stationary night blindness (HP:0007642)1.89759974
122Abnormality of the heme biosynthetic pathway (HP:0010472)1.89546899
123Hemiplegia (HP:0002301)1.88594428
124Pulmonary fibrosis (HP:0002206)1.80673275
125Paresthesia (HP:0003401)1.80196282
126Renal cortical cysts (HP:0000803)1.77565879
127Hepatosplenomegaly (HP:0001433)1.75789883
128Abnormality of male internal genitalia (HP:0000022)1.75129976
129Increased hepatocellular lipid droplets (HP:0006565)1.72147523
130Alveolar cell carcinoma (HP:0006519)1.71048154
131Oral leukoplakia (HP:0002745)1.67785072
132Decreased activity of mitochondrial respiratory chain (HP:0008972)1.66820487
133Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.66820487
134Increased intramyocellular lipid droplets (HP:0012240)1.66017824
135Lipid accumulation in hepatocytes (HP:0006561)1.65708812
136Abnormality of the pons (HP:0007361)1.65194923

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME25.39198805
2TXK4.05192720
3MAP4K13.97767906
4STK163.38646591
5KIT3.11117254
6FLT32.87115724
7JAK32.44637868
8TEC2.44061603
9IRAK42.39914762
10BTK2.22367034
11ZAP702.15301907
12MAP3K142.13434880
13TBK11.85292561
14IKBKE1.81830263
15SYK1.79401618
16EPHA31.76754444
17CSF1R1.74506597
18TNIK1.70799837
19ITK1.64075301
20BLK1.62548146
21TYK21.58168772
22PIM21.56271686
23IRAK31.49946559
24TESK11.49029032
25EEF2K1.47287757
26SCYL21.45652308
27NLK1.40914307
28IKBKB1.40610069
29MAP2K31.38607176
30LCK1.36169285
31WNK41.34089338
32MAP3K121.33157851
33MAP4K21.29452455
34NUAK11.27849390
35FES1.27677673
36CLK11.26930257
37TGFBR11.24429255
38PIM11.23376206
39WEE11.21546967
40JAK11.20820355
41TAOK31.19689877
42PIK3CG1.17009141
43ADRBK21.13052198
44LYN1.08143431
45CAMKK21.06447574
46MUSK0.99239186
47SIK30.95793138
48RPS6KB20.95144408
49HCK0.95089713
50BMPR20.93753982
51ACVR1B0.93391372
52VRK10.87913683
53CDK190.87789511
54CHUK0.87527343
55TYRO30.86046599
56GRK60.83576697
57RIPK40.83272010
58FRK0.83226047
59TGFBR20.82053545
60TSSK60.81689270
61STK390.80169882
62PKN20.79657706
63FGFR40.79258886
64TESK20.78781306
65MST40.78541222
66STK100.77910875
67MATK0.77843402
68MAP3K130.72625755
69VRK20.71870579
70TLK10.70866133
71BCKDK0.70803951
72NEK90.70381656
73CSK0.68353811
74EIF2AK30.67593133
75BUB10.67300049
76TAOK20.66932165
77FGFR30.66652772
78MAPKAPK50.65922653
79MARK30.65884075
80BRSK20.65723544
81MAP3K30.65241379
82OXSR10.63644803
83CCNB10.63414272
84MAPK110.58599356
85LRRK20.57542523
86TRPM70.55757165
87ATR0.55419642
88GRK10.54283856
89MAP2K60.54272247
90PASK0.53342718
91KDR0.52971792
92MKNK10.51971147
93ZAK0.51486347
94PDK10.51015489
95PRKCH0.50316789
96CDK80.50291223
97TNK20.50132735
98JAK20.48678051
99GRK70.48579024
100IRAK10.47588563
101CDK40.47302124
102ALK0.45990296
103FYN0.44393729
104DAPK10.43826652
105EIF2AK10.42815221
106MAPK130.42568672
107MAPK40.42106771
108RPS6KA40.41952003
109MAPKAPK30.41891323
110IGF1R0.41408384
111DYRK30.39604503
112CDK70.38566585
113MAP3K60.38476853
114RPS6KA60.36548434
115MAPKAPK20.36483906
116HIPK20.36276789
117STK40.35107920
118PDGFRB0.34203677
119PIK3CA0.33805322
120RPS6KA50.33509701
121MYLK0.32705792
122EIF2AK20.32702843
123PRKCQ0.32238994
124MAP3K110.32043364
125CDK90.30972017
126CDC70.30662698
127SRPK10.29762727
128RPS6KB10.29690026
129EPHB10.29177827
130PRKCD0.29124442
131MKNK20.28974923
132PAK30.28125736
133INSR0.25096473
134STK380.24428982
135CAMKK10.22444687
136CAMK2A0.21696535
137DAPK20.18877478
138PRKCA0.18623078
139EGFR0.18113758

Predicted pathways (KEGG)

RankGene SetZ-score
1Allograft rejection_Homo sapiens_hsa053303.63536904
2Primary immunodeficiency_Homo sapiens_hsa053403.62018252
3Graft-versus-host disease_Homo sapiens_hsa053323.32765682
4Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.92819098
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.75302857
6DNA replication_Homo sapiens_hsa030302.59225678
7Ribosome_Homo sapiens_hsa030102.46968845
8Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.43708550
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.37078524
10Measles_Homo sapiens_hsa051622.36625061
11Leishmaniasis_Homo sapiens_hsa051402.31617701
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.28372677
13Antigen processing and presentation_Homo sapiens_hsa046122.17145780
14RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.02805679
15Type I diabetes mellitus_Homo sapiens_hsa049402.01116446
16Mismatch repair_Homo sapiens_hsa034301.94426951
17B cell receptor signaling pathway_Homo sapiens_hsa046621.93853199
18Herpes simplex infection_Homo sapiens_hsa051681.91691336
19Hematopoietic cell lineage_Homo sapiens_hsa046401.84166610
20Autoimmune thyroid disease_Homo sapiens_hsa053201.81752351
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.78278435
22T cell receptor signaling pathway_Homo sapiens_hsa046601.68917423
23Osteoclast differentiation_Homo sapiens_hsa043801.60712992
24Base excision repair_Homo sapiens_hsa034101.60407517
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.52342189
26Toll-like receptor signaling pathway_Homo sapiens_hsa046201.49822472
27Legionellosis_Homo sapiens_hsa051341.41299061
28Homologous recombination_Homo sapiens_hsa034401.38467621
29Asthma_Homo sapiens_hsa053101.37396612
30Influenza A_Homo sapiens_hsa051641.35091038
31Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.34882082
32Non-homologous end-joining_Homo sapiens_hsa034501.34405791
33Spliceosome_Homo sapiens_hsa030401.29008542
34Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.28873436
35Pertussis_Homo sapiens_hsa051331.24957830
36Transcriptional misregulation in cancer_Homo sapiens_hsa052021.21135884
37Malaria_Homo sapiens_hsa051441.20266157
38Acute myeloid leukemia_Homo sapiens_hsa052211.15711278
39Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.09686359
40Viral myocarditis_Homo sapiens_hsa054161.09461967
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.09121035
42Toxoplasmosis_Homo sapiens_hsa051451.08934963
43Hepatitis B_Homo sapiens_hsa051611.07539214
44Shigellosis_Homo sapiens_hsa051311.07470882
45Pyrimidine metabolism_Homo sapiens_hsa002401.06671442
46Oxidative phosphorylation_Homo sapiens_hsa001901.02068795
47RNA polymerase_Homo sapiens_hsa030201.01551667
48Platelet activation_Homo sapiens_hsa046110.98956897
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.98911523
50RNA degradation_Homo sapiens_hsa030180.97577279
51Tuberculosis_Homo sapiens_hsa051520.96806486
52Nucleotide excision repair_Homo sapiens_hsa034200.96364147
53Parkinsons disease_Homo sapiens_hsa050120.95049949
54Apoptosis_Homo sapiens_hsa042100.94403639
55Epstein-Barr virus infection_Homo sapiens_hsa051690.93866735
56Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.92623098
57Chemokine signaling pathway_Homo sapiens_hsa040620.92456646
58TNF signaling pathway_Homo sapiens_hsa046680.91750798
59Proteasome_Homo sapiens_hsa030500.91269329
60Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.89049156
61African trypanosomiasis_Homo sapiens_hsa051430.88771660
62Salmonella infection_Homo sapiens_hsa051320.87964516
63p53 signaling pathway_Homo sapiens_hsa041150.87436492
64Leukocyte transendothelial migration_Homo sapiens_hsa046700.82354174
65Linoleic acid metabolism_Homo sapiens_hsa005910.80551434
66alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.77800087
67Other glycan degradation_Homo sapiens_hsa005110.77031197
68Fanconi anemia pathway_Homo sapiens_hsa034600.74872209
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.71998905
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70677236
71Cell cycle_Homo sapiens_hsa041100.69529049
72Viral carcinogenesis_Homo sapiens_hsa052030.67385565
73Hepatitis C_Homo sapiens_hsa051600.66770239
74Phototransduction_Homo sapiens_hsa047440.64907942
75Protein export_Homo sapiens_hsa030600.61935278
76HTLV-I infection_Homo sapiens_hsa051660.60231588
77Nitrogen metabolism_Homo sapiens_hsa009100.59604308
78Rheumatoid arthritis_Homo sapiens_hsa053230.58044031
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.56661952
80RNA transport_Homo sapiens_hsa030130.56588844
81Caffeine metabolism_Homo sapiens_hsa002320.55876278
82N-Glycan biosynthesis_Homo sapiens_hsa005100.51272672
83Thyroid cancer_Homo sapiens_hsa052160.50724294
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49855495
85Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48143783
86AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.47155180
87Basal transcription factors_Homo sapiens_hsa030220.46402098
88Systemic lupus erythematosus_Homo sapiens_hsa053220.43732381
89Chronic myeloid leukemia_Homo sapiens_hsa052200.43392573
90Staphylococcus aureus infection_Homo sapiens_hsa051500.42062533
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41364159
92Purine metabolism_Homo sapiens_hsa002300.40552747
93One carbon pool by folate_Homo sapiens_hsa006700.40411630
94Alzheimers disease_Homo sapiens_hsa050100.40147611
95Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39447574
96Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.38698699
97Prolactin signaling pathway_Homo sapiens_hsa049170.37975465
98Small cell lung cancer_Homo sapiens_hsa052220.37916470
99Pancreatic cancer_Homo sapiens_hsa052120.36652056
100Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.35843997
101Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.35423040
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.34956993
103Huntingtons disease_Homo sapiens_hsa050160.32941080
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.28903672
105mRNA surveillance pathway_Homo sapiens_hsa030150.28700011
106Regulation of autophagy_Homo sapiens_hsa041400.27579419
107Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.26858154
108Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26652099
109Ether lipid metabolism_Homo sapiens_hsa005650.25259681
110Fatty acid biosynthesis_Homo sapiens_hsa000610.24766823
111Colorectal cancer_Homo sapiens_hsa052100.24737477
112Non-small cell lung cancer_Homo sapiens_hsa052230.23383676
113Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.20860313
114Peroxisome_Homo sapiens_hsa041460.18522211
115Olfactory transduction_Homo sapiens_hsa047400.18443268
116Arachidonic acid metabolism_Homo sapiens_hsa005900.17795987
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.17398091
118Circadian rhythm_Homo sapiens_hsa047100.17264597
119FoxO signaling pathway_Homo sapiens_hsa040680.17110539
120Collecting duct acid secretion_Homo sapiens_hsa049660.10643992
121Endocytosis_Homo sapiens_hsa041440.09829723
122MAPK signaling pathway_Homo sapiens_hsa040100.09561235
123Vascular smooth muscle contraction_Homo sapiens_hsa042700.06190649
124Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.05527511
125Drug metabolism - other enzymes_Homo sapiens_hsa009830.05041512
126ABC transporters_Homo sapiens_hsa020100.03841450
127Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.02791860

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